## Wed Jul 10 16:19:48 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_934841635.1/GCA_934841635.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934841635.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934841635.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NIGDIANH_00001	411469.EUBHAL_02435	8.45e-88	261.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
NIGDIANH_00002	411469.EUBHAL_02435	3.94e-55	177.0	2C83V@1|root,2Z99X@2|Bacteria,1TQYC@1239|Firmicutes,24E4W@186801|Clostridia,25WKJ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990,HTH_3
NIGDIANH_00003	411469.EUBHAL_02436	2.66e-107	310.0	29H8K@1|root,30465@2|Bacteria,1V42R@1239|Firmicutes,24H9W@186801|Clostridia,25YFS@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00004	411469.EUBHAL_02437	1.96e-86	256.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,25X4A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00005	411469.EUBHAL_02438	2.78e-152	429.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,25VQ7@186806|Eubacteriaceae	186801|Clostridia	I	1-acyl-sn-glycerol-3-phosphate acyltransferase	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NIGDIANH_00006	411469.EUBHAL_02439	0.0	1053.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,25UZT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NIGDIANH_00007	411469.EUBHAL_02441	1.53e-245	674.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25X36@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NIGDIANH_00008	411469.EUBHAL_02442	0.0	979.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,25UY7@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
NIGDIANH_00009	411469.EUBHAL_02443	3.45e-202	559.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NIGDIANH_00010	411469.EUBHAL_02444	1.08e-218	603.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NIGDIANH_00011	411469.EUBHAL_02445	0.0	988.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NIGDIANH_00012	411469.EUBHAL_02446	3.13e-231	638.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25XEF@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439,ko:K17202	ko02010,ko02030,map02010,map02030	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	Peripla_BP_4
NIGDIANH_00013	411469.EUBHAL_02447	1.39e-147	417.0	COG5618@1|root,COG5618@2|Bacteria,1V221@1239|Firmicutes,24G1Q@186801|Clostridia	186801|Clostridia	S	Predicted periplasmic lipoprotein (DUF2291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2291
NIGDIANH_00014	411469.EUBHAL_02448	0.0	998.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25ZMX@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K17204	ko02010,map02010	M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
NIGDIANH_00015	411469.EUBHAL_02449	7.16e-236	650.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,25WRW@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
NIGDIANH_00016	411469.EUBHAL_02450	0.0	1307.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,25V55@186806|Eubacteriaceae	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NIGDIANH_00017	411469.EUBHAL_02451	5.75e-93	272.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,25WIG@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NIGDIANH_00018	411469.EUBHAL_02452	3.83e-312	852.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,25VE8@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NIGDIANH_00019	411469.EUBHAL_02453	1.86e-157	447.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia,25WJ7@186806|Eubacteriaceae	186801|Clostridia	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NIGDIANH_00020	411469.EUBHAL_02454	1.69e-18	77.4	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,25ZK7@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NIGDIANH_00021	411469.EUBHAL_02455	3.43e-139	395.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes	1239|Firmicutes	P	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
NIGDIANH_00022	411469.EUBHAL_02456	2.24e-303	826.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,25V85@186806|Eubacteriaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
NIGDIANH_00023	411469.EUBHAL_02457	3.4e-164	459.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,25W1I@186806|Eubacteriaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
NIGDIANH_00024	411469.EUBHAL_02458	2.77e-292	797.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,25UWS@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10830	DHBP_synthase,GTP_cyclohydro2
NIGDIANH_00025	411469.EUBHAL_02459	2.26e-109	315.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,25W25@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
NIGDIANH_00026	411469.EUBHAL_02462	3.36e-42	138.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,25X8I@186806|Eubacteriaceae	186801|Clostridia	D	Hydrid cluster protein-associated redox disulfide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NIGDIANH_00027	411469.EUBHAL_02463	4.59e-199	554.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia,25WD2@186806|Eubacteriaceae	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
NIGDIANH_00028	411469.EUBHAL_02464	1.17e-38	134.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,25WGE@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NIGDIANH_00029	411469.EUBHAL_02465	1.09e-251	691.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,25UZS@186806|Eubacteriaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NIGDIANH_00031	658088.HMPREF0987_01956	3.31e-05	45.1	2DR0U@1|root,339Q9@2|Bacteria	2|Bacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	atpZ	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
NIGDIANH_00032	411469.EUBHAL_02468	5.27e-91	266.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia,25XZ4@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
NIGDIANH_00033	411469.EUBHAL_02469	2.59e-161	452.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NIGDIANH_00034	411469.EUBHAL_02470	4e-49	157.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NIGDIANH_00035	411469.EUBHAL_02471	8.91e-85	254.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia,25ZJA@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NIGDIANH_00036	411469.EUBHAL_02472	5.1e-121	347.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia,25WJZ@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NIGDIANH_00037	411469.EUBHAL_02473	0.0	964.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NIGDIANH_00038	411469.EUBHAL_02474	8.63e-192	533.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NIGDIANH_00039	411469.EUBHAL_02475	0.0	905.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NIGDIANH_00040	411469.EUBHAL_02476	3.09e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,25WYB@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
NIGDIANH_00041	411469.EUBHAL_02478	3.26e-117	335.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia,25WX0@186806|Eubacteriaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
NIGDIANH_00043	411469.EUBHAL_02480	1.75e-35	122.0	COG4932@1|root,COG4932@2|Bacteria,1VQ5U@1239|Firmicutes	1239|Firmicutes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00044	411469.EUBHAL_02480	4.58e-06	52.0	COG4932@1|root,COG4932@2|Bacteria,1VQ5U@1239|Firmicutes	1239|Firmicutes	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00045	411469.EUBHAL_02482	2.14e-147	415.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,25WYY@186806|Eubacteriaceae	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NIGDIANH_00047	411469.EUBHAL_02484	5.12e-286	781.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,25VBV@186806|Eubacteriaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
NIGDIANH_00048	411469.EUBHAL_02485	0.0	1637.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,25VUN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NIGDIANH_00050	411469.EUBHAL_02317	9.04e-280	765.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NIGDIANH_00051	411469.EUBHAL_02316	3.24e-307	838.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,25URW@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NIGDIANH_00052	411469.EUBHAL_02315	2.46e-139	393.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25W2D@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NIGDIANH_00053	411469.EUBHAL_02314	4.57e-97	282.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,25WUY@186806|Eubacteriaceae	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NIGDIANH_00054	411469.EUBHAL_02313	6.84e-270	748.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NIGDIANH_00055	411469.EUBHAL_02313	1.85e-184	527.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NIGDIANH_00056	411469.EUBHAL_02311	0.0	1221.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NIGDIANH_00057	411469.EUBHAL_02310	1.47e-212	587.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,25VK7@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NIGDIANH_00058	411469.EUBHAL_02309	0.0	885.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,24DGD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NIGDIANH_00059	411469.EUBHAL_02308	1.05e-152	429.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,25ZQZ@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
NIGDIANH_00060	411469.EUBHAL_02307	0.0	868.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,25XET@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3,dCache_1
NIGDIANH_00061	411469.EUBHAL_02306	1.65e-223	617.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NIGDIANH_00063	411469.EUBHAL_02304	1.7e-54	170.0	COG1925@1|root,COG1925@2|Bacteria,1TTT4@1239|Firmicutes,25N1G@186801|Clostridia,25XST@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11184	-	-	-	-	ko00000	-	-	-	PTS-HPr
NIGDIANH_00064	411469.EUBHAL_02303	1.74e-223	616.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,25VF1@186806|Eubacteriaceae	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NIGDIANH_00065	411469.EUBHAL_02302	3.88e-207	573.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,25UUB@186806|Eubacteriaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NIGDIANH_00066	411469.EUBHAL_02301	5.23e-214	594.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,25UUJ@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NIGDIANH_00067	411469.EUBHAL_02299	6.55e-223	618.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,25UYM@186806|Eubacteriaceae	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NIGDIANH_00068	411469.EUBHAL_02297	0.0	1238.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,25VJV@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NIGDIANH_00069	411469.EUBHAL_02296	0.0	1190.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UYJ@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NIGDIANH_00070	411469.EUBHAL_02295	2.32e-196	544.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,25VN4@186806|Eubacteriaceae	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NIGDIANH_00071	411469.EUBHAL_02294	1.78e-154	436.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,25W6C@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NIGDIANH_00072	411469.EUBHAL_02293	2.62e-261	716.0	COG1454@1|root,COG1454@2|Bacteria,1UGWW@1239|Firmicutes,24A5G@186801|Clostridia,25VNW@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NIGDIANH_00073	411469.EUBHAL_02292	7.49e-236	649.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,25USZ@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NIGDIANH_00074	411469.EUBHAL_02291	0.0	2277.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,25V2U@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NIGDIANH_00075	411469.EUBHAL_02290	5.61e-277	757.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,25V17@186806|Eubacteriaceae	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	yjiM	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NIGDIANH_00076	411469.EUBHAL_02289	2.78e-170	476.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NIGDIANH_00077	411469.EUBHAL_02288	5.41e-87	256.0	COG0657@1|root,COG0657@2|Bacteria,1TT1M@1239|Firmicutes,24FY3@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NIGDIANH_00078	411469.EUBHAL_02287	0.0	1338.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NIGDIANH_00079	411469.EUBHAL_02286	3.44e-122	348.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NIGDIANH_00080	411469.EUBHAL_00059	9.96e-141	397.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,25WCD@186806|Eubacteriaceae	186801|Clostridia	F	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_00081	411469.EUBHAL_00060	0.0	1192.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,25V8P@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NIGDIANH_00082	411469.EUBHAL_00061	4.64e-169	472.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia,25WC1@186806|Eubacteriaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
NIGDIANH_00083	411469.EUBHAL_00063	1.97e-314	861.0	2E2WU@1|root,32XY0@2|Bacteria,1VDG4@1239|Firmicutes,24NB8@186801|Clostridia,25ZB6@186806|Eubacteriaceae	186801|Clostridia	S	LytR cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
NIGDIANH_00084	411469.EUBHAL_00064	4.31e-195	541.0	COG1922@1|root,COG1922@2|Bacteria,1V3QV@1239|Firmicutes,24AQ3@186801|Clostridia,25XW7@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase WecB/TagA/CpsF family	tagA	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
NIGDIANH_00085	411469.EUBHAL_00066	2.48e-170	476.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V1F@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NIGDIANH_00086	411469.EUBHAL_02341	6.77e-255	700.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25V2S@186806|Eubacteriaceae	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NIGDIANH_00087	411469.EUBHAL_02343	8.59e-290	793.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,25VR7@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
NIGDIANH_00088	411469.EUBHAL_02344	2.07e-111	320.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,25X7Z@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00089	411469.EUBHAL_02345	1.04e-234	649.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,25VMC@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NIGDIANH_00090	411469.EUBHAL_02345	1.35e-64	207.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,25VMC@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NIGDIANH_00091	411469.EUBHAL_02346	0.0	956.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,25VU1@186806|Eubacteriaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
NIGDIANH_00092	411469.EUBHAL_02347	3.69e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25VVW@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NIGDIANH_00093	411469.EUBHAL_02348	0.0	995.0	COG0144@1|root,COG0144@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,25V2B@186806|Eubacteriaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NIGDIANH_00094	411469.EUBHAL_02350	3.93e-162	455.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,25W6P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NIGDIANH_00095	411469.EUBHAL_02352	0.0	1348.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,25VRA@186806|Eubacteriaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NIGDIANH_00096	411469.EUBHAL_02353	1.74e-175	489.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	sdh	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NIGDIANH_00097	411469.EUBHAL_02354	1.47e-270	744.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,25VUW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RluA family	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NIGDIANH_00098	411469.EUBHAL_02355	1.1e-131	373.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,25W2C@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
NIGDIANH_00099	411469.EUBHAL_02356	1.69e-196	546.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,25VXT@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NIGDIANH_00100	411469.EUBHAL_02357	5.85e-56	174.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,25X81@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF370)	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NIGDIANH_00101	411469.EUBHAL_02358	3.4e-145	410.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,25WGB@186806|Eubacteriaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NIGDIANH_00102	411469.EUBHAL_02359	3.43e-61	188.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,25Q91@186801|Clostridia,25X3H@186806|Eubacteriaceae	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	-	-	-	-	-	-	-	-	-	-	RNA_pol_Rpb6
NIGDIANH_00103	411469.EUBHAL_02360	1.57e-177	496.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	VanZ
NIGDIANH_00104	411469.EUBHAL_02361	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,25VGR@186806|Eubacteriaceae	186801|Clostridia	M	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NIGDIANH_00105	411469.EUBHAL_02362	0.0	1466.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,25V1S@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NIGDIANH_00106	411469.EUBHAL_02363	5.02e-110	316.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,25WDW@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NIGDIANH_00107	411469.EUBHAL_02364	8.96e-223	614.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,25UWW@186806|Eubacteriaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NIGDIANH_00108	411469.EUBHAL_02365	0.0	885.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,25VS9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NIGDIANH_00109	411469.EUBHAL_02366	8.32e-254	696.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,25UW3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NIGDIANH_00110	411469.EUBHAL_02367	8.67e-171	477.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,25W72@186806|Eubacteriaceae	186801|Clostridia	T	phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NIGDIANH_00111	411469.EUBHAL_02368	4.77e-211	599.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NIGDIANH_00112	411469.EUBHAL_02368	4.21e-229	647.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,25VI6@186806|Eubacteriaceae	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NIGDIANH_00113	411469.EUBHAL_00005	4.26e-222	612.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,25USA@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, pyridine binding domain protein	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NIGDIANH_00114	411469.EUBHAL_00004	9.91e-204	563.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain protein	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NIGDIANH_00115	411469.EUBHAL_00003	7.45e-150	422.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NIGDIANH_00116	411469.EUBHAL_00298	1.9e-99	288.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,25WT1@186806|Eubacteriaceae	186801|Clostridia	C	Fe-S iron-sulfur cluster assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NIGDIANH_00117	411469.EUBHAL_00297	1.71e-283	775.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NIGDIANH_00118	411469.EUBHAL_00295	1.65e-93	273.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NIGDIANH_00120	411469.EUBHAL_03046	4.15e-298	815.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00121	411469.EUBHAL_03045	1.5e-96	281.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NIGDIANH_00122	411469.EUBHAL_03044	1.7e-140	397.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,25WJA@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
NIGDIANH_00123	411469.EUBHAL_03043	0.0	1330.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,25UW5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
NIGDIANH_00124	411469.EUBHAL_03042	3.21e-61	189.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,25X8R@186806|Eubacteriaceae	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00125	411469.EUBHAL_03041	3.19e-37	125.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,25X97@186806|Eubacteriaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NIGDIANH_00126	411469.EUBHAL_03040	1.56e-294	805.0	COG1649@1|root,COG1649@2|Bacteria,1TRTG@1239|Firmicutes,24B2F@186801|Clostridia,25W6I@186806|Eubacteriaceae	186801|Clostridia	S	lipoprotein YddW precursor K01189	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,GHL10,SLH
NIGDIANH_00127	411469.EUBHAL_03038	1.47e-181	505.0	COG2197@1|root,COG2203@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,1V0Q0@1239|Firmicutes,2495W@186801|Clostridia,25Z4B@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
NIGDIANH_00128	411469.EUBHAL_03037	9.28e-267	735.0	COG0463@1|root,COG0463@2|Bacteria,1VVRP@1239|Firmicutes,24GDS@186801|Clostridia,25ZK9@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PS_pyruv_trans
NIGDIANH_00129	411469.EUBHAL_03036	9.15e-201	582.0	29ZI5@1|root,30MI8@2|Bacteria,1V4FB@1239|Firmicutes,25FNW@186801|Clostridia,25ZQI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00130	272562.CA_C3042	2.69e-20	96.3	COG3594@1|root,COG3594@2|Bacteria,1VCBH@1239|Firmicutes,25DT8@186801|Clostridia	186801|Clostridia	M	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NIGDIANH_00131	411469.EUBHAL_03034	3.63e-187	532.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_00132	411469.EUBHAL_03033	2.73e-198	552.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,25ZUQ@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_00133	411469.EUBHAL_03032	8.65e-275	751.0	COG1216@1|root,COG1216@2|Bacteria,1UZWY@1239|Firmicutes,24A9S@186801|Clostridia,25ZP8@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_00134	411469.EUBHAL_03031	3.68e-272	744.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,25UYR@186806|Eubacteriaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NIGDIANH_00135	411469.EUBHAL_03030	5.03e-296	808.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,25VF9@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
NIGDIANH_00136	411469.EUBHAL_03196	0.0	872.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,25VTI@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NIGDIANH_00137	411469.EUBHAL_03195	2.48e-175	489.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,25WXU@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NIGDIANH_00138	411469.EUBHAL_03194	7.36e-94	274.0	COG3610@1|root,COG3610@2|Bacteria	2|Bacteria	H	response to peptide	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NIGDIANH_00139	411469.EUBHAL_00006	6.66e-233	641.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,25V13@186806|Eubacteriaceae	186801|Clostridia	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS15750	ALAD
NIGDIANH_00140	411469.EUBHAL_00007	1.33e-100	291.0	COG0454@1|root,COG0454@2|Bacteria,1VD9I@1239|Firmicutes,24MT9@186801|Clostridia,25X3U@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
NIGDIANH_00141	411469.EUBHAL_00008	2.69e-194	540.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,25X6M@186806|Eubacteriaceae	186801|Clostridia	H	Putative NAD(P)-binding	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
NIGDIANH_00142	411469.EUBHAL_00009	0.0	1343.0	COG1492@1|root,COG2109@1|root,COG1492@2|Bacteria,COG2109@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,25VJ2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
NIGDIANH_00143	411469.EUBHAL_00010	5.06e-259	709.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,25UXQ@186806|Eubacteriaceae	186801|Clostridia	E	Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NIGDIANH_00144	411469.EUBHAL_00011	2.14e-233	643.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,25UVZ@186806|Eubacteriaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
NIGDIANH_00145	411469.EUBHAL_00012	0.0	933.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,25UZ5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
NIGDIANH_00146	411469.EUBHAL_00013	1.49e-164	461.0	COG2099@1|root,COG2099@2|Bacteria,1UHWY@1239|Firmicutes,24GIQ@186801|Clostridia,25W9J@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-6x reductase CbiJ/CobK	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
NIGDIANH_00147	411469.EUBHAL_00014	1.09e-158	445.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,25W9U@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NIGDIANH_00148	411469.EUBHAL_00015	1.83e-185	515.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,25W2F@186806|Eubacteriaceae	186801|Clostridia	H	Cobalt chelatase (CbiK)	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
NIGDIANH_00149	411469.EUBHAL_00016	3.72e-301	821.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,25W2I@186806|Eubacteriaceae	186801|Clostridia	H	precorrin-6y C5,15-methyltransferase	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NIGDIANH_00150	411469.EUBHAL_00017	1.75e-255	701.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,25UST@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NIGDIANH_00151	411469.EUBHAL_00018	7.22e-149	419.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,25W34@186806|Eubacteriaceae	186801|Clostridia	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
NIGDIANH_00152	411469.EUBHAL_00019	6.84e-255	699.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,25VHG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NIGDIANH_00153	411469.EUBHAL_00020	1.35e-166	468.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NIGDIANH_00154	411469.EUBHAL_00021	0.0	1618.0	COG0007@1|root,COG0181@1|root,COG0007@2|Bacteria,COG0181@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,25V51@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
NIGDIANH_00155	411469.EUBHAL_00022	6.35e-177	493.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,25V3N@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NIGDIANH_00156	411469.EUBHAL_00023	1.06e-280	767.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,25VG7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
NIGDIANH_00157	411469.EUBHAL_00024	1.62e-174	487.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,25V19@186806|Eubacteriaceae	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NIGDIANH_00158	411469.EUBHAL_00025	2.11e-310	845.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,25VID@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NIGDIANH_00159	411469.EUBHAL_00026	0.0	1313.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NIGDIANH_00160	411469.EUBHAL_00027	0.0	1359.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,25KHW@186801|Clostridia,25USX@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NIGDIANH_00161	411469.EUBHAL_00028	1.42e-215	594.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,25VXD@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NIGDIANH_00162	411469.EUBHAL_00029	1.05e-219	605.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NIGDIANH_00163	411469.EUBHAL_00030	4.49e-262	716.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,25VJ0@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NIGDIANH_00164	411469.EUBHAL_00708	9.54e-150	422.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,25WT5@186806|Eubacteriaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
NIGDIANH_00165	411469.EUBHAL_00709	9.9e-203	560.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,25VQW@186806|Eubacteriaceae	186801|Clostridia	I	phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NIGDIANH_00166	411469.EUBHAL_00710	3.63e-159	447.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,25WGS@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NIGDIANH_00167	411469.EUBHAL_00711	3.56e-239	659.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,25VXA@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NIGDIANH_00168	411469.EUBHAL_00713	4.64e-156	440.0	2AYHW@1|root,2Z7XM@2|Bacteria,1UPEA@1239|Firmicutes,25BDY@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NIGDIANH_00169	411469.EUBHAL_00714	6.91e-281	767.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25V28@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NIGDIANH_00170	411469.EUBHAL_00715	1.61e-69	211.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,25WHU@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NIGDIANH_00171	411469.EUBHAL_00716	3.86e-114	328.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,25W5X@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NIGDIANH_00172	411469.EUBHAL_00718	0.0	918.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,25UX6@186806|Eubacteriaceae	186801|Clostridia	O	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NIGDIANH_00173	411469.EUBHAL_00719	0.0	944.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,25ZX3@186806|Eubacteriaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
NIGDIANH_00174	411469.EUBHAL_00720	2.09e-305	834.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WDT@186806|Eubacteriaceae	186801|Clostridia	K	function transcriptional attenuator common domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NIGDIANH_00175	411469.EUBHAL_00721	0.0	1944.0	COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00176	411469.EUBHAL_00722	9.53e-207	572.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,25VVK@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
NIGDIANH_00177	411469.EUBHAL_02084	5.45e-51	189.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
NIGDIANH_00178	411469.EUBHAL_00725	2.73e-266	728.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,25VKX@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NIGDIANH_00179	411469.EUBHAL_00726	2.05e-153	431.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,25WCR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
NIGDIANH_00180	411469.EUBHAL_00655	1.88e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00181	411469.EUBHAL_00656	6.72e-78	231.0	COG0640@1|root,COG0640@2|Bacteria,1VINN@1239|Firmicutes,24S2F@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
NIGDIANH_00183	411469.EUBHAL_00512	1.37e-104	305.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_00184	411469.EUBHAL_00513	0.0	888.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25URU@186806|Eubacteriaceae	186801|Clostridia	C	RnfC Barrel sandwich hybrid domain	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
NIGDIANH_00185	411469.EUBHAL_00514	0.0	913.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,25UXF@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde dehydrogenase (NAD) family protein	pduP	-	1.2.1.87	ko:K13922	ko00640,map00640	-	R09097	RC00004,RC00184	ko00000,ko00001,ko01000	-	-	-	Aldedh
NIGDIANH_00186	411469.EUBHAL_00515	7.47e-235	647.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,25VCA@186806|Eubacteriaceae	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans,Haem_degrading
NIGDIANH_00187	411469.EUBHAL_00516	7.91e-55	171.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,25WU3@186806|Eubacteriaceae	186801|Clostridia	CQ	Ethanolamine utilisation protein EutN/carboxysome	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
NIGDIANH_00188	411469.EUBHAL_00517	1.34e-201	559.0	COG0452@1|root,COG0452@2|Bacteria,1V24V@1239|Firmicutes,24F67@186801|Clostridia,25W9C@186806|Eubacteriaceae	186801|Clostridia	H	Flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Flavoprotein
NIGDIANH_00189	411469.EUBHAL_00518	4.13e-188	523.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,25VHK@186806|Eubacteriaceae	186801|Clostridia	E	Type IV pilus assembly protein PilM;	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,MreB_Mbl,PilM_2
NIGDIANH_00190	411469.EUBHAL_00519	2.67e-102	305.0	COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_00191	411469.EUBHAL_00520	3.8e-80	238.0	2EB43@1|root,3354T@2|Bacteria,1VC2J@1239|Firmicutes,24R33@186801|Clostridia,25X32@186806|Eubacteriaceae	186801|Clostridia	S	Dehydratase medium subunit	-	-	-	-	-	-	-	-	-	-	-	-	Dehydratase_MU
NIGDIANH_00192	411469.EUBHAL_00521	0.0	1150.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
NIGDIANH_00193	411469.EUBHAL_00522	3.92e-110	317.0	COG4910@1|root,COG4910@2|Bacteria,1V5ZV@1239|Firmicutes,24KHN@186801|Clostridia,25W9N@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase small subunit	pduE	-	4.2.1.28,4.2.1.30	ko:K06122,ko:K13920	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_SU
NIGDIANH_00194	411469.EUBHAL_00523	3.16e-152	428.0	COG4909@1|root,COG4909@2|Bacteria,1UT3J@1239|Firmicutes,24GDN@186801|Clostridia,25VQS@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase medium subunit	pduD	-	4.2.1.28,4.2.1.30	ko:K06121,ko:K13919	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_MU
NIGDIANH_00195	411469.EUBHAL_00524	0.0	1092.0	COG4909@1|root,COG4909@2|Bacteria,1TPU7@1239|Firmicutes,24AFR@186801|Clostridia,25V3Z@186806|Eubacteriaceae	186801|Clostridia	Q	Dehydratase large subunit	dhaB	-	4.2.1.28,4.2.1.30	ko:K01699,ko:K06120	ko00561,ko00640,map00561,map00640	-	R01047,R02376	RC00429,RC00707	ko00000,ko00001,ko01000	-	-	-	Dehydratase_LU
NIGDIANH_00196	411469.EUBHAL_00525	2.39e-186	518.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduB	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_00197	411469.EUBHAL_00526	1.01e-52	166.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_00198	411469.EUBHAL_00527	8.3e-274	749.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25US3@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K13921	ko00640,map00640	-	R02377	RC00087	ko00000,ko00001	-	-	-	Fe-ADH
NIGDIANH_00199	411469.EUBHAL_00528	2.26e-245	675.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia,25V1K@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NIGDIANH_00200	411469.EUBHAL_00529	1.09e-293	802.0	COG2972@1|root,COG4936@1|root,COG2972@2|Bacteria,COG4936@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25VDS@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HATPase_c,His_kinase,PocR,dCache_1
NIGDIANH_00201	411469.EUBHAL_00530	1.24e-154	434.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,25WHI@186806|Eubacteriaceae	186801|Clostridia	S	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
NIGDIANH_00202	411469.EUBHAL_00532	0.0	1635.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NIGDIANH_00203	411469.EUBHAL_00533	1.56e-66	223.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,25UTF@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
NIGDIANH_00204	411469.EUBHAL_02205	1.18e-225	622.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,25UU4@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
NIGDIANH_00205	411469.EUBHAL_02206	1.81e-41	136.0	COG0236@1|root,COG0236@2|Bacteria,1TU8C@1239|Firmicutes,25P5Z@186801|Clostridia,25XX1@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NIGDIANH_00206	411469.EUBHAL_02207	1.11e-213	591.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia,25USN@186806|Eubacteriaceae	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
NIGDIANH_00207	411469.EUBHAL_02208	1.87e-218	603.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,25VUM@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NIGDIANH_00208	411469.EUBHAL_02209	8.39e-155	437.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NIGDIANH_00209	411469.EUBHAL_02210	7.99e-293	800.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,25UYT@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NIGDIANH_00210	411469.EUBHAL_02211	6.35e-97	284.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,25XAJ@186806|Eubacteriaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
NIGDIANH_00211	411469.EUBHAL_02212	1.1e-98	286.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,25WHY@186806|Eubacteriaceae	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NIGDIANH_00212	411469.EUBHAL_02213	0.0	892.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,25V5Q@186806|Eubacteriaceae	186801|Clostridia	I	Acetyl-CoA carboxylase, biotin carboxylase subunit	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NIGDIANH_00213	411469.EUBHAL_02214	0.0	1155.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,25V1B@186806|Eubacteriaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
NIGDIANH_00214	1280698.AUJS01000022_gene1305	6.71e-159	456.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NIGDIANH_00215	411469.EUBHAL_02217	1.1e-102	297.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,25WME@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NIGDIANH_00216	411469.EUBHAL_02218	1.4e-231	640.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23,Peptidase_M56
NIGDIANH_00217	411469.EUBHAL_02219	2.3e-94	276.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NIGDIANH_00219	411469.EUBHAL_02221	0.0	1114.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,25UY3@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NIGDIANH_00220	411469.EUBHAL_02223	1.99e-151	426.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,25VIM@186806|Eubacteriaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NIGDIANH_00221	411469.EUBHAL_02225	0.0	979.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,25UYP@186806|Eubacteriaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NIGDIANH_00222	411469.EUBHAL_02226	9.89e-76	226.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,25WS1@186806|Eubacteriaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NIGDIANH_00223	411469.EUBHAL_02227	4.05e-288	786.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,2491B@186801|Clostridia,25USW@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class I and II	dapL2	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_00224	411469.EUBHAL_02228	4.27e-169	473.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,25V1H@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NIGDIANH_00225	411469.EUBHAL_01748	7.17e-82	243.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,25W8Y@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NIGDIANH_00226	411469.EUBHAL_01749	1.32e-121	348.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,25UZ9@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NIGDIANH_00227	411469.EUBHAL_01750	4.07e-76	228.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,25WB4@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NIGDIANH_00228	411469.EUBHAL_01751	3.15e-109	315.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,25WCN@186806|Eubacteriaceae	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NIGDIANH_00229	411469.EUBHAL_01752	1.24e-35	120.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,25X9Q@186806|Eubacteriaceae	186801|Clostridia	J	COG1841 Ribosomal protein L30 L7E	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NIGDIANH_00230	411469.EUBHAL_01753	1.12e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,25WJV@186806|Eubacteriaceae	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NIGDIANH_00231	411469.EUBHAL_01754	7.96e-308	840.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,25USD@186806|Eubacteriaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NIGDIANH_00232	411469.EUBHAL_01755	0.0	968.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae	186801|Clostridia	P	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
NIGDIANH_00233	411469.EUBHAL_01756	3.35e-307	837.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VR2@186806|Eubacteriaceae	186801|Clostridia	C	Pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
NIGDIANH_00234	411469.EUBHAL_01757	2.37e-79	236.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,25WVW@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
NIGDIANH_00236	411469.EUBHAL_00631	1.77e-155	436.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,25UWE@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NIGDIANH_00237	411469.EUBHAL_00632	6.52e-60	185.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,25XNX@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NIGDIANH_00238	411469.EUBHAL_00633	7.06e-93	271.0	COG1669@1|root,COG1669@2|Bacteria,1V7CK@1239|Firmicutes,25DJI@186801|Clostridia,25X02@186806|Eubacteriaceae	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
NIGDIANH_00239	411469.EUBHAL_00634	4.17e-191	530.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25V68@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NIGDIANH_00240	411469.EUBHAL_00635	6.08e-63	192.0	2A0AP@1|root,30NE4@2|Bacteria,1UHB1@1239|Firmicutes,25Q15@186801|Clostridia,25Y02@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00241	411469.EUBHAL_00636	3.42e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,25WYK@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NIGDIANH_00242	411469.EUBHAL_00637	7.32e-79	234.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25WK3@186806|Eubacteriaceae	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NIGDIANH_00243	411469.EUBHAL_00638	2.85e-69	211.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,25W9E@186806|Eubacteriaceae	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NIGDIANH_00244	411469.EUBHAL_00639	1.72e-136	386.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,25VYW@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NIGDIANH_00245	411469.EUBHAL_00640	8.86e-218	602.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,25UT6@186806|Eubacteriaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NIGDIANH_00246	411469.EUBHAL_00641	5.2e-115	330.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,25W4B@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NIGDIANH_00247	411469.EUBHAL_00642	0.0	1357.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25URB@186806|Eubacteriaceae	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NIGDIANH_00248	411469.EUBHAL_00643	4.24e-180	503.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,25UR8@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NIGDIANH_00249	411469.EUBHAL_00644	4.83e-185	514.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,25US1@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NIGDIANH_00250	411469.EUBHAL_00645	7.13e-100	289.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,25WEH@186806|Eubacteriaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NIGDIANH_00251	411469.EUBHAL_00566	0.0	956.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25VVU@186806|Eubacteriaceae	186801|Clostridia	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
NIGDIANH_00252	411469.EUBHAL_00567	0.0	999.0	COG0554@1|root,COG0554@2|Bacteria,1V02F@1239|Firmicutes,24C5X@186801|Clostridia,25UZV@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NIGDIANH_00253	411469.EUBHAL_00568	2.41e-150	423.0	COG1461@1|root,COG1461@2|Bacteria,1V1ZG@1239|Firmicutes,24CF0@186801|Clostridia,25VWQ@186806|Eubacteriaceae	186801|Clostridia	S	Dak2	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
NIGDIANH_00254	411469.EUBHAL_00569	1.42e-244	671.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25V93@186806|Eubacteriaceae	186801|Clostridia	G	Dak1 domain	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
NIGDIANH_00255	411469.EUBHAL_00570	2.87e-83	246.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25X2F@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, phosphotransfer subunit	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
NIGDIANH_00256	411469.EUBHAL_00571	1.19e-184	513.0	COG0149@1|root,COG0149@2|Bacteria,1UYUE@1239|Firmicutes,248TQ@186801|Clostridia,25WD9@186806|Eubacteriaceae	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1,5.3.1.33	ko:K01803,ko:K21910	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
NIGDIANH_00257	411469.EUBHAL_00572	7.88e-247	679.0	COG0544@1|root,COG0544@2|Bacteria,1V21F@1239|Firmicutes,24G64@186801|Clostridia,25YV8@186806|Eubacteriaceae	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C
NIGDIANH_00258	411469.EUBHAL_02574	4.7e-12	61.6	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia,25Z6G@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00259	411469.EUBHAL_00574	0.0	1108.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,25URY@186806|Eubacteriaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
NIGDIANH_00260	411469.EUBHAL_00575	0.0	1058.0	COG4990@1|root,COG4990@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,Lysozyme_like,Peptidase_C39_2,SH3_3
NIGDIANH_00261	411469.EUBHAL_00576	0.0	1354.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,25VB6@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
NIGDIANH_00262	411469.EUBHAL_00577	1.67e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25X9W@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
NIGDIANH_00263	411469.EUBHAL_00578	1.34e-176	492.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W8W@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
NIGDIANH_00264	411469.EUBHAL_00579	2.45e-223	617.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,25XCS@186806|Eubacteriaceae	186801|Clostridia	P	Substrate binding domain of ABC-type glycine betaine transport system	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2,Phosphonate-bd
NIGDIANH_00265	411469.EUBHAL_00580	1.6e-247	679.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,25WAY@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NIGDIANH_00266	411469.EUBHAL_00581	0.0	898.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NIGDIANH_00267	411469.EUBHAL_01204	6.56e-135	382.0	COG0860@1|root,COG0860@2|Bacteria,1V0RH@1239|Firmicutes,24DWG@186801|Clostridia	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NIGDIANH_00268	411469.EUBHAL_02890	6.11e-106	306.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,25W1A@186806|Eubacteriaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NIGDIANH_00269	411469.EUBHAL_02889	0.0	1561.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,25URR@186806|Eubacteriaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NIGDIANH_00270	411469.EUBHAL_02888	3.46e-40	133.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,24QMG@186801|Clostridia,25X7Y@186806|Eubacteriaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
NIGDIANH_00271	411469.EUBHAL_02887	1.24e-298	815.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NIGDIANH_00272	411469.EUBHAL_02886	8.8e-217	600.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,25WA2@186806|Eubacteriaceae	186801|Clostridia	U	Branched-chain amino acid transport system / permease component	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NIGDIANH_00273	411469.EUBHAL_02885	6.15e-259	710.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,25W0W@186806|Eubacteriaceae	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NIGDIANH_00274	411469.EUBHAL_02884	0.0	981.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,25UYU@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NIGDIANH_00275	411469.EUBHAL_02882	1.39e-266	731.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NIGDIANH_00276	411469.EUBHAL_02881	9.08e-181	511.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NIGDIANH_00277	411469.EUBHAL_02881	3.71e-52	176.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NIGDIANH_00278	411469.EUBHAL_02880	6.71e-147	413.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,25WQM@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_00279	411469.EUBHAL_02879	3.24e-158	444.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,25VVG@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
NIGDIANH_00280	411469.EUBHAL_02878	5.63e-176	491.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,25VQJ@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
NIGDIANH_00281	411469.EUBHAL_02877	2.6e-238	657.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,25WAG@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NIGDIANH_00282	411469.EUBHAL_02876	6.9e-187	522.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,25VFQ@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NIGDIANH_00283	411469.EUBHAL_02875	6.74e-267	732.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae	186801|Clostridia	E	Periplasmic binding protein	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
NIGDIANH_00284	411469.EUBHAL_02873	7.85e-205	566.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,25VYS@186806|Eubacteriaceae	186801|Clostridia	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
NIGDIANH_00285	626939.HMPREF9443_00891	7.92e-47	154.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,4H9ET@909932|Negativicutes	909932|Negativicutes	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NIGDIANH_00286	411469.EUBHAL_01700	2.81e-117	337.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NIGDIANH_00287	411469.EUBHAL_01701	9.5e-247	681.0	2DBN5@1|root,2ZA1Y@2|Bacteria,1UZYG@1239|Firmicutes,249F5@186801|Clostridia,25Z5P@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NIGDIANH_00288	411469.EUBHAL_01702	2.35e-138	391.0	COG1595@1|root,COG1595@2|Bacteria,1V55A@1239|Firmicutes,24GME@186801|Clostridia,25X6S@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NIGDIANH_00289	411469.EUBHAL_01703	0.0	1222.0	COG0122@1|root,COG0561@1|root,COG0122@2|Bacteria,COG0561@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,25WET@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
NIGDIANH_00290	411469.EUBHAL_01704	4.11e-222	611.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,25B4M@186801|Clostridia,25VYJ@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NIGDIANH_00291	411469.EUBHAL_01705	0.0	1075.0	COG2340@1|root,COG2340@2|Bacteria,1VQ1W@1239|Firmicutes,24W63@186801|Clostridia	186801|Clostridia	S	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
NIGDIANH_00292	411469.EUBHAL_01706	0.0	2048.0	2DB7E@1|root,2Z7KT@2|Bacteria,1V0PC@1239|Firmicutes,24D3B@186801|Clostridia,25VZ1@186806|Eubacteriaceae	186801|Clostridia	S	Penicillin-binding protein Tp47 domain a	-	-	-	-	-	-	-	-	-	-	-	-	DUF1533,PBP-Tp47_a,PBP-Tp47_c
NIGDIANH_00293	411469.EUBHAL_01707	6.36e-257	706.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NIGDIANH_00294	411469.EUBHAL_01708	6.62e-255	713.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,25WV2@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
NIGDIANH_00295	411469.EUBHAL_01708	8.85e-33	125.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,25WV2@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
NIGDIANH_00296	411469.EUBHAL_01709	1.21e-99	290.0	COG3976@1|root,COG3976@2|Bacteria,1VENM@1239|Firmicutes,24RRX@186801|Clostridia,25YW3@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
NIGDIANH_00297	411469.EUBHAL_01710	5.34e-183	511.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25WT0@186806|Eubacteriaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
NIGDIANH_00298	411469.EUBHAL_01711	4.56e-216	598.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,25UR5@186806|Eubacteriaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NIGDIANH_00299	411469.EUBHAL_01036	9.9e-245	673.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,25WAM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00300	411469.EUBHAL_01037	2.6e-193	536.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,25X9K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NIGDIANH_00301	411469.EUBHAL_01038	0.0	1516.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25UXK@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NIGDIANH_00302	411469.EUBHAL_01038	2.35e-62	212.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,25UXK@186806|Eubacteriaceae	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NIGDIANH_00303	411469.EUBHAL_01039	1.87e-294	805.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NIGDIANH_00305	411469.EUBHAL_01041	0.0	922.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia,25VCT@186806|Eubacteriaceae	186801|Clostridia	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
NIGDIANH_00306	411469.EUBHAL_01042	8e-75	225.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,25XEZ@186806|Eubacteriaceae	186801|Clostridia	T	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NIGDIANH_00307	411469.EUBHAL_01043	8.76e-104	300.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,25WSM@186806|Eubacteriaceae	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NIGDIANH_00308	411469.EUBHAL_01044	1.2e-159	449.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,25W1Y@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03090,ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NIGDIANH_00309	411469.EUBHAL_01045	1.34e-155	437.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,25WBQ@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AA	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
NIGDIANH_00310	411469.EUBHAL_01046	2.11e-88	261.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,25WZR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
NIGDIANH_00311	411469.EUBHAL_01048	4.05e-303	827.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,25V8Z@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NIGDIANH_00312	411469.EUBHAL_01049	1.71e-176	494.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia,25XMF@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00313	411469.EUBHAL_01050	9.69e-158	443.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,25V9M@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NIGDIANH_00314	411469.EUBHAL_01051	4.56e-78	233.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,25WY8@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NIGDIANH_00315	411469.EUBHAL_00402	4.52e-51	162.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	eamA	-	-	-	-	-	-	-	-	-	-	-	EamA
NIGDIANH_00316	411469.EUBHAL_00404	0.0	1019.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,25V72@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NIGDIANH_00317	471875.RUMLAC_01414	5.12e-101	293.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,3WJ68@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NIGDIANH_00319	411469.EUBHAL_00823	0.0	869.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,25VHT@186806|Eubacteriaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NIGDIANH_00320	411469.EUBHAL_00824	1.77e-282	771.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia,25X00@186806|Eubacteriaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NIGDIANH_00321	411469.EUBHAL_00826	2.49e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,25V06@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NIGDIANH_00323	411469.EUBHAL_00828	8.88e-296	804.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia,25VYX@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
NIGDIANH_00324	411469.EUBHAL_00328	1.25e-187	520.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NIGDIANH_00325	411469.EUBHAL_00329	9.37e-129	365.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,25WAI@186806|Eubacteriaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NIGDIANH_00326	411469.EUBHAL_00330	1.73e-256	703.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,25VJ9@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NIGDIANH_00327	411469.EUBHAL_00331	4.44e-55	171.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,25XED@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NIGDIANH_00328	411469.EUBHAL_00332	1.26e-162	456.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,25W3M@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NIGDIANH_00329	411469.EUBHAL_00333	4.11e-150	423.0	2EICA@1|root,334KH@2|Bacteria,1VIYE@1239|Firmicutes,24T0X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00330	411469.EUBHAL_00334	3.12e-190	529.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,25VJ8@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NIGDIANH_00331	411469.EUBHAL_00336	8.9e-131	371.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,25WMT@186806|Eubacteriaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NIGDIANH_00332	411469.EUBHAL_00337	1.74e-61	188.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,25X8P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00333	411469.EUBHAL_00338	3.84e-264	723.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,25VKP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NIGDIANH_00334	411469.EUBHAL_00339	1.05e-132	376.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,25XK5@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
NIGDIANH_00335	411469.EUBHAL_01137	2.92e-183	525.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,25V6C@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
NIGDIANH_00337	411469.EUBHAL_01136	0.0	882.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia,25VPP@186806|Eubacteriaceae	186801|Clostridia	V	VanW like protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
NIGDIANH_00338	411469.EUBHAL_01135	5.43e-231	639.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25UTJ@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NIGDIANH_00339	411469.EUBHAL_01134	3.51e-111	320.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,25WGY@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
NIGDIANH_00340	411469.EUBHAL_01133	1.52e-284	777.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,25VAD@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_00341	411469.EUBHAL_01132	1.17e-115	331.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,25W60@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NIGDIANH_00342	411469.EUBHAL_01130	0.0	1393.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,25UUQ@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NIGDIANH_00343	411469.EUBHAL_01129	1.17e-65	199.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,25XUI@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NIGDIANH_00344	411469.EUBHAL_01128	6.36e-48	162.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,25VNH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NIGDIANH_00345	411469.EUBHAL_01128	3.09e-150	426.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,25VNH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NIGDIANH_00346	411469.EUBHAL_01127	0.0	944.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UR4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NIGDIANH_00347	411469.EUBHAL_01126	0.0	942.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UVHK@1239|Firmicutes,24DE9@186801|Clostridia,25YAP@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
NIGDIANH_00348	33035.JPJF01000008_gene1220	1.08e-09	60.5	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3XZQG@572511|Blautia	186801|Clostridia	KL	Psort location Cytoplasmic, score 8.87	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
NIGDIANH_00350	411469.EUBHAL_01123	1.36e-268	737.0	COG0477@1|root,COG2814@2|Bacteria,1TQXU@1239|Firmicutes,24MJI@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K08159,ko:K08164	-	-	-	-	ko00000,ko02000	2.A.1.2,2.A.1.2.15,2.A.1.2.18	-	-	MFS_1,Sugar_tr
NIGDIANH_00351	411469.EUBHAL_00802	1.19e-192	535.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia,25ZHR@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_00352	411469.EUBHAL_00800	1.7e-154	433.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,25VT0@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NIGDIANH_00353	411469.EUBHAL_00799	0.0	873.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB_3	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PBP5_C,Peptidase_S11
NIGDIANH_00354	411469.EUBHAL_00349	1.13e-307	838.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,25VBF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NIGDIANH_00355	411469.EUBHAL_02549	1.26e-212	587.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,25VM6@186806|Eubacteriaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	2.7.1.107	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_cat
NIGDIANH_00356	411469.EUBHAL_02551	6.38e-159	445.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,25W40@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00357	411469.EUBHAL_02552	0.0	891.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,25EVD@186801|Clostridia,25ZUN@186806|Eubacteriaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_00358	411469.EUBHAL_02553	2.34e-286	781.0	COG1874@1|root,COG1874@2|Bacteria,1V23M@1239|Firmicutes,24GDA@186801|Clostridia,25Y5E@186806|Eubacteriaceae	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00359	411469.EUBHAL_02554	1.97e-97	283.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NIGDIANH_00360	411469.EUBHAL_02555	1.71e-105	304.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,25WH5@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NIGDIANH_00361	411469.EUBHAL_02557	0.0	934.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,25WG6@186806|Eubacteriaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c_5,HisKA
NIGDIANH_00362	411469.EUBHAL_02558	1.26e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VZY@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00363	411469.EUBHAL_02559	1.83e-140	404.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,25XA1@186806|Eubacteriaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
NIGDIANH_00364	411469.EUBHAL_02559	1.5e-125	365.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,25XA1@186806|Eubacteriaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
NIGDIANH_00365	411469.EUBHAL_02560	3.74e-59	183.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,25YZG@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NIGDIANH_00366	411469.EUBHAL_02576	1.29e-129	367.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
NIGDIANH_00367	411469.EUBHAL_02575	4.94e-75	224.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,25WP7@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
NIGDIANH_00368	411469.EUBHAL_02573	0.0	1023.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,25UZX@186806|Eubacteriaceae	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NIGDIANH_00369	411469.EUBHAL_02572	2.61e-235	647.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NIGDIANH_00370	411469.EUBHAL_02571	5.05e-146	412.0	2C11U@1|root,33VPV@2|Bacteria,1VVR2@1239|Firmicutes,250UF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00371	411469.EUBHAL_02569	0.0	1090.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25WPE@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NIGDIANH_00372	411469.EUBHAL_02568	0.0	1055.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25XBG@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NIGDIANH_00373	411469.EUBHAL_02567	0.0	880.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia,25ZNV@186806|Eubacteriaceae	186801|Clostridia	G	Vacuole effluxer Atg22 like	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
NIGDIANH_00374	411469.EUBHAL_02566	2.45e-146	411.0	COG4123@1|root,COG4123@2|Bacteria,1UK35@1239|Firmicutes,25FHR@186801|Clostridia,25XJC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
NIGDIANH_00375	411469.EUBHAL_02565	1.85e-97	289.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,25XDV@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NIGDIANH_00376	411469.EUBHAL_02564	1.05e-84	251.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,Lant_dehydr_N,MarR,MarR_2
NIGDIANH_00377	411469.EUBHAL_02563	5.28e-139	393.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_00378	411469.EUBHAL_02562	0.0	1508.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25VTE@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NIGDIANH_00380	411469.EUBHAL_03276	2.26e-286	782.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,25VFC@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	ftsI	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
NIGDIANH_00381	411469.EUBHAL_03275	0.0	1006.0	COG0772@1|root,COG0772@2|Bacteria,1UISM@1239|Firmicutes,250R6@186801|Clostridia	186801|Clostridia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
NIGDIANH_00382	411469.EUBHAL_03274	2.59e-184	516.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NIGDIANH_00383	411469.EUBHAL_03273	0.0	1048.0	2CSF7@1|root,32SR4@2|Bacteria,1VBPZ@1239|Firmicutes,24NZR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00385	411469.EUBHAL_03271	0.0	947.0	2DU4N@1|root,33NXD@2|Bacteria,1VNU8@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00387	411469.EUBHAL_03269	3.46e-188	525.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,25XXS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NIGDIANH_00388	411469.EUBHAL_03268	1.62e-227	625.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,25VAK@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NIGDIANH_00389	411469.EUBHAL_03267	9.55e-170	476.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,25XKS@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NIGDIANH_00390	411469.EUBHAL_03265	0.0	1084.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,25VE5@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NIGDIANH_00393	411469.EUBHAL_00900	2.1e-192	536.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,25W3K@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NIGDIANH_00394	411469.EUBHAL_00901	0.0	1774.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia,25V75@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
NIGDIANH_00395	411469.EUBHAL_00902	9.42e-174	484.0	COG1216@1|root,COG1216@2|Bacteria,1V3IY@1239|Firmicutes,24GIC@186801|Clostridia,25WHC@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_00397	357809.Cphy_3422	6.59e-13	64.3	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,221FT@1506553|Lachnoclostridium	186801|Clostridia	S	Small, acid-soluble spore proteins, alpha/beta type	-	-	-	-	-	-	-	-	-	-	-	-	SASP
NIGDIANH_00398	411469.EUBHAL_00905	0.0	868.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,25VCM@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NIGDIANH_00400	411469.EUBHAL_00907	0.0	1194.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia,25VGD@186806|Eubacteriaceae	186801|Clostridia	E	oligoendopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
NIGDIANH_00401	411469.EUBHAL_00908	0.0	1181.0	COG5279@1|root,COG5492@1|root,COG5279@2|Bacteria,COG5492@2|Bacteria,1VQT7@1239|Firmicutes	1239|Firmicutes	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NIGDIANH_00403	411469.EUBHAL_00910	5.49e-102	295.0	COG0369@1|root,COG1151@2|Bacteria,1VM38@1239|Firmicutes,24WM1@186801|Clostridia	186801|Clostridia	P	hydroxylamine reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00404	411469.EUBHAL_00911	0.0	1352.0	COG0073@1|root,COG1384@1|root,COG0073@2|Bacteria,COG1384@2|Bacteria,1TR1T@1239|Firmicutes,24DBQ@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04566	ko00970,map00970	M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1f,tRNA_bind
NIGDIANH_00405	411469.EUBHAL_02407	4.64e-139	394.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,25WIU@186806|Eubacteriaceae	186801|Clostridia	S	stage II sporulation protein R	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
NIGDIANH_00406	411469.EUBHAL_00872	0.0	1194.0	COG0531@1|root,COG0531@2|Bacteria,1TZQ6@1239|Firmicutes,24EQ1@186801|Clostridia	186801|Clostridia	E	TIGRFAM Spore germination	-	-	-	ko:K06296,ko:K06311	-	-	-	-	ko00000,ko02000	2.A.3.9.3,2.A.3.9.4	-	-	Spore_permease
NIGDIANH_00407	411469.EUBHAL_00873	0.0	999.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,25V1Z@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310,ko:K06408	-	-	-	-	ko00000	-	-	-	GerA
NIGDIANH_00408	411469.EUBHAL_00874	2.31e-232	639.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,25VAB@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NIGDIANH_00409	411469.EUBHAL_00875	3.13e-149	421.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,25V16@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ydfH_4	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NIGDIANH_00410	411469.EUBHAL_00876	2.91e-201	559.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,25WDG@186806|Eubacteriaceae	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NIGDIANH_00411	411469.EUBHAL_00877	3.14e-74	223.0	2DDNB@1|root,2ZING@2|Bacteria	2|Bacteria	S	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NIGDIANH_00412	411469.EUBHAL_00880	0.0	1012.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,25VZU@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NIGDIANH_00413	411469.EUBHAL_00881	5.21e-62	193.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,25X54@186806|Eubacteriaceae	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
NIGDIANH_00414	411469.EUBHAL_00882	0.0	887.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,25VGZ@186806|Eubacteriaceae	186801|Clostridia	H	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NIGDIANH_00415	411469.EUBHAL_00883	1.85e-85	263.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,25W8P@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat protein	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
NIGDIANH_00416	411469.EUBHAL_03135	0.0	1133.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,25VGI@186806|Eubacteriaceae	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NIGDIANH_00418	411469.EUBHAL_03133	1.62e-168	471.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,25W3T@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
NIGDIANH_00419	411469.EUBHAL_03132	0.0	1231.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,25UR2@186806|Eubacteriaceae	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NIGDIANH_00420	411469.EUBHAL_03131	0.0	888.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,25URZ@186806|Eubacteriaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NIGDIANH_00421	411469.EUBHAL_03130	2.14e-141	400.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,25UVE@186806|Eubacteriaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NIGDIANH_00422	411469.EUBHAL_03129	1.35e-299	818.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,25VNJ@186806|Eubacteriaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NIGDIANH_00423	411469.EUBHAL_03128	2.09e-45	146.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,25XH9@186806|Eubacteriaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NIGDIANH_00424	411469.EUBHAL_03127	1.57e-77	231.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,25X1N@186806|Eubacteriaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NIGDIANH_00425	411469.EUBHAL_03126	7.96e-21	82.4	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,25XP8@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NIGDIANH_00426	411469.EUBHAL_03125	0.0	876.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,25UYE@186806|Eubacteriaceae	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NIGDIANH_00427	411469.EUBHAL_03124	2.07e-260	714.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,25UUV@186806|Eubacteriaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NIGDIANH_00428	411469.EUBHAL_03123	7.4e-41	134.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,25XAF@186806|Eubacteriaceae	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NIGDIANH_00429	411469.EUBHAL_03122	1.45e-258	709.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,25V7R@186806|Eubacteriaceae	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NIGDIANH_00430	411469.EUBHAL_01777	1.02e-163	459.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W3X@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
NIGDIANH_00431	411469.EUBHAL_01776	9.53e-241	662.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,25V7T@186806|Eubacteriaceae	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NIGDIANH_00432	411469.EUBHAL_01775	2.95e-207	573.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,25VP6@186806|Eubacteriaceae	186801|Clostridia	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NIGDIANH_00433	411469.EUBHAL_01774	9.13e-52	162.0	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia,25XPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00434	411469.EUBHAL_01773	1.13e-97	284.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,25XAS@186806|Eubacteriaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
NIGDIANH_00435	411469.EUBHAL_01772	1.01e-164	461.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,25UTC@186806|Eubacteriaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NIGDIANH_00436	411469.EUBHAL_01771	1.09e-99	289.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,25WM6@186806|Eubacteriaceae	186801|Clostridia	S	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NIGDIANH_00437	411469.EUBHAL_01770	6.07e-165	462.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia,25XQM@186806|Eubacteriaceae	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
NIGDIANH_00438	411469.EUBHAL_01769	0.0	1341.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,25VB8@186806|Eubacteriaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
NIGDIANH_00439	411469.EUBHAL_01768	3.09e-267	731.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,25V7Q@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NIGDIANH_00440	411469.EUBHAL_01766	0.0	1692.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,25VEZ@186806|Eubacteriaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NIGDIANH_00441	411469.EUBHAL_01764	4.68e-121	345.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,25W4P@186806|Eubacteriaceae	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NIGDIANH_00442	411469.EUBHAL_01763	8.18e-132	375.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia,25XZM@186806|Eubacteriaceae	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NIGDIANH_00443	411469.EUBHAL_01762	2.49e-181	504.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,25W47@186806|Eubacteriaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NIGDIANH_00444	411469.EUBHAL_01761	1.42e-175	491.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,25ZIP@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NIGDIANH_00445	411469.EUBHAL_02086	1.6e-221	613.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,25W1K@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
NIGDIANH_00446	411469.EUBHAL_02085	4.36e-280	765.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25VYN@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NIGDIANH_00447	411469.EUBHAL_02084	0.0	1031.0	COG1376@1|root,COG4733@1|root,COG1376@2|Bacteria,COG4733@2|Bacteria,1V6QN@1239|Firmicutes,24IAP@186801|Clostridia,25XWN@186806|Eubacteriaceae	186801|Clostridia	G	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,SH3_3,YkuD
NIGDIANH_00448	411469.EUBHAL_02083	0.0	1581.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,25WP9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NIGDIANH_00449	411469.EUBHAL_02083	7.68e-221	641.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,25WP9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NIGDIANH_00450	411469.EUBHAL_02082	1.1e-81	242.0	COG3682@1|root,COG3682@2|Bacteria,1VHDV@1239|Firmicutes,25HPH@186801|Clostridia,25Z8X@186806|Eubacteriaceae	1239|Firmicutes	K	Transcriptional regulator, BlaI MecI CopY family	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NIGDIANH_00451	411469.EUBHAL_02080	1.93e-214	592.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NIGDIANH_00452	411469.EUBHAL_02079	3.53e-231	638.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,25VZ9@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NIGDIANH_00453	411469.EUBHAL_02078	6.04e-201	559.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,25WB6@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NIGDIANH_00454	411469.EUBHAL_02077	2.39e-180	502.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,25V8K@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NIGDIANH_00456	411469.EUBHAL_01091	1.21e-267	731.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
NIGDIANH_00457	411469.EUBHAL_01090	1.11e-194	539.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,25WID@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
NIGDIANH_00458	411469.EUBHAL_01089	8.83e-315	859.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,25VJ6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NIGDIANH_00459	411469.EUBHAL_01088	2.58e-310	847.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00460	411469.EUBHAL_01087	2.14e-258	708.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,25W1D@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
NIGDIANH_00461	411469.EUBHAL_01086	2.36e-131	373.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,25WAX@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
NIGDIANH_00462	411469.EUBHAL_01085	3.04e-201	558.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,25VF3@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
NIGDIANH_00463	411469.EUBHAL_01083	8.89e-305	832.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UT2@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
NIGDIANH_00464	411469.EUBHAL_01082	5.67e-157	440.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,25V2E@186806|Eubacteriaceae	186801|Clostridia	K	Response regulator receiver domain	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00465	411469.EUBHAL_01081	0.0	1083.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NIGDIANH_00466	411469.EUBHAL_01080	1.01e-141	401.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,25WEB@186806|Eubacteriaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NIGDIANH_00467	411469.EUBHAL_00933	2.82e-314	856.0	2DBS2@1|root,2ZAP4@2|Bacteria,1V6HV@1239|Firmicutes,24K80@186801|Clostridia,25WP5@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00468	411469.EUBHAL_00934	0.0	1090.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,25VDG@186806|Eubacteriaceae	186801|Clostridia	H	Formyltetrahydrofolate synthetase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NIGDIANH_00471	411469.EUBHAL_00552	0.0	981.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,25UWV@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NIGDIANH_00472	411469.EUBHAL_00553	4.29e-144	408.0	2E6QY@1|root,331B3@2|Bacteria,1VGA3@1239|Firmicutes,24QJZ@186801|Clostridia,25ZD3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
NIGDIANH_00473	411469.EUBHAL_00555	6.18e-130	368.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,25W8H@186806|Eubacteriaceae	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NIGDIANH_00474	411469.EUBHAL_00556	0.0	1449.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,25UVA@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NIGDIANH_00475	411469.EUBHAL_00557	7.1e-243	671.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,25XJU@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
NIGDIANH_00476	411469.EUBHAL_00558	1.42e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1V2HA@1239|Firmicutes,24G2X@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00477	411469.EUBHAL_00058	5.43e-294	804.0	COG2710@1|root,COG2710@2|Bacteria,1TRSJ@1239|Firmicutes,24AEW@186801|Clostridia,25VUX@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
NIGDIANH_00478	411469.EUBHAL_00057	1.72e-210	588.0	COG2710@1|root,COG2710@2|Bacteria,1TS4H@1239|Firmicutes,24BC1@186801|Clostridia,25VYK@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
NIGDIANH_00479	411469.EUBHAL_00057	2.93e-62	202.0	COG2710@1|root,COG2710@2|Bacteria,1TS4H@1239|Firmicutes,24BC1@186801|Clostridia,25VYK@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
NIGDIANH_00480	411469.EUBHAL_00056	1.67e-172	482.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25VIN@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	nifH1	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
NIGDIANH_00481	411469.EUBHAL_00055	5.27e-49	156.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,25XEG@186806|Eubacteriaceae	186801|Clostridia	K	iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00482	411469.EUBHAL_00054	1.3e-240	661.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,25VSI@186806|Eubacteriaceae	186801|Clostridia	O	AIR synthase related protein, N-terminal domain	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NIGDIANH_00483	411469.EUBHAL_00053	7.77e-260	711.0	COG0409@1|root,COG0409@2|Bacteria,1TPM7@1239|Firmicutes,248EX@186801|Clostridia,25UTZ@186806|Eubacteriaceae	186801|Clostridia	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
NIGDIANH_00484	411469.EUBHAL_00052	4.29e-40	132.0	COG0298@1|root,COG0298@2|Bacteria,1VEMQ@1239|Firmicutes,24RN2@186801|Clostridia	186801|Clostridia	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS11355	HupF_HypC
NIGDIANH_00485	411469.EUBHAL_00051	0.0	1108.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,25VWK@186806|Eubacteriaceae	186801|Clostridia	O	HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
NIGDIANH_00486	411469.EUBHAL_00051	5.5e-142	425.0	COG0068@1|root,COG0068@2|Bacteria,1TQM7@1239|Firmicutes,2494A@186801|Clostridia,25VWK@186806|Eubacteriaceae	186801|Clostridia	O	HypF finger	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
NIGDIANH_00487	411469.EUBHAL_00050	7.43e-256	701.0	COG2710@1|root,COG2710@2|Bacteria,1TSY8@1239|Firmicutes,24BHA@186801|Clostridia,25VXY@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_nitro
NIGDIANH_00488	411469.EUBHAL_00049	0.0	876.0	COG2710@1|root,COG2710@2|Bacteria,1U1IK@1239|Firmicutes,25DHB@186801|Clostridia,25VXR@186806|Eubacteriaceae	186801|Clostridia	C	Nitrogenase component 1 type Oxidoreductase	-	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
NIGDIANH_00489	411469.EUBHAL_00048	1.62e-183	510.0	COG1348@1|root,COG1348@2|Bacteria,1TPXR@1239|Firmicutes,247KJ@186801|Clostridia,25W01@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the NifH BchL ChlL family	-	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
NIGDIANH_00490	411469.EUBHAL_00047	3.85e-218	607.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,25VUF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NIGDIANH_00491	411469.EUBHAL_00270	1.04e-148	429.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25VM4@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NIGDIANH_00492	411469.EUBHAL_00269	6.36e-54	168.0	2E9QS@1|root,333X3@2|Bacteria,1VHZY@1239|Firmicutes,24S7Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00493	411469.EUBHAL_00267	0.0	875.0	COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,2493B@186801|Clostridia,25VD2@186806|Eubacteriaceae	186801|Clostridia	M	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NIGDIANH_00494	411469.EUBHAL_00266	1.31e-220	609.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NIGDIANH_00495	411469.EUBHAL_00123	9.32e-252	690.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,25UV7@186806|Eubacteriaceae	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
NIGDIANH_00496	411469.EUBHAL_00122	0.0	1612.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NIGDIANH_00497	411469.EUBHAL_00121	1.37e-247	679.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25VAC@186806|Eubacteriaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NIGDIANH_00498	411469.EUBHAL_00120	1.94e-145	410.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NIGDIANH_00499	411469.EUBHAL_00119	2.97e-219	606.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,25WIZ@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0761 family	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
NIGDIANH_00500	411469.EUBHAL_00118	1.63e-146	412.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,25WD5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00501	411469.EUBHAL_00116	1.38e-54	179.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,25VN8@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
NIGDIANH_00502	411469.EUBHAL_00395	1.22e-127	364.0	COG2816@1|root,COG2816@2|Bacteria,1VAYJ@1239|Firmicutes,24JR2@186801|Clostridia,25ZFN@186806|Eubacteriaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NIGDIANH_00503	411469.EUBHAL_00394	0.0	941.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,25VHC@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NIGDIANH_00504	411469.EUBHAL_00393	0.0	956.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,25V2X@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NIGDIANH_00505	411469.EUBHAL_00392	1.17e-61	189.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,25X2Y@186806|Eubacteriaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NIGDIANH_00506	411469.EUBHAL_00391	0.0	2646.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,25WTM@186806|Eubacteriaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00507	411469.EUBHAL_00390	7.12e-170	474.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,25YDD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00508	411469.EUBHAL_00389	0.0	1019.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,25XIF@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00509	411469.EUBHAL_00388	1.91e-236	650.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,25XMN@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
NIGDIANH_00511	411469.EUBHAL_00250	1.46e-261	723.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25WQW@186806|Eubacteriaceae	186801|Clostridia	N	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NIGDIANH_00512	411469.EUBHAL_00251	5.7e-114	328.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,25WG3@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NIGDIANH_00513	411469.EUBHAL_00252	1.82e-186	518.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25VA9@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
NIGDIANH_00514	411469.EUBHAL_00253	9.85e-99	287.0	COG4578@1|root,COG4578@2|Bacteria,1VHYU@1239|Firmicutes,24P6V@186801|Clostridia	186801|Clostridia	K	Glucitol operon activator	-	-	-	ko:K02466	-	-	-	-	ko00000	-	-	-	GutM
NIGDIANH_00515	411469.EUBHAL_00254	6.32e-128	363.0	COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,24DNG@186801|Clostridia,25W6B@186806|Eubacteriaceae	186801|Clostridia	G	PTS system enzyme II sorbitol-specific factor	srlA	-	-	ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.4.1	-	-	EII-GUT
NIGDIANH_00516	411469.EUBHAL_00255	5.92e-236	649.0	COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,2491P@186801|Clostridia,25VDV@186806|Eubacteriaceae	186801|Clostridia	G	Sorbitol phosphotransferase enzyme II N-terminus	srlE	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0090563	2.7.1.198	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	EIIBC-GUT_C,EIIBC-GUT_N
NIGDIANH_00517	411469.EUBHAL_00256	1.65e-82	244.0	COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,24QUT@186801|Clostridia,25XAW@186806|Eubacteriaceae	186801|Clostridia	G	PTS system glucitol/sorbitol-specific IIA component	-	-	2.7.1.198	ko:K02781	ko00051,ko02060,map00051,map02060	M00280	R05820	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.4.1	-	-	PTSIIA_gutA
NIGDIANH_00518	411469.EUBHAL_00257	0.0	1192.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,249R8@186801|Clostridia,25XAI@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
NIGDIANH_00520	411469.EUBHAL_02166	2.56e-49	177.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NIGDIANH_00521	411469.EUBHAL_00260	3.56e-153	430.0	COG3773@1|root,COG3773@2|Bacteria,1VN9A@1239|Firmicutes,25PXG@186801|Clostridia,25XWP@186806|Eubacteriaceae	186801|Clostridia	M	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5,Hydrolase_2
NIGDIANH_00522	411469.EUBHAL_01367	1.47e-199	560.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,25Y6V@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
NIGDIANH_00523	411469.EUBHAL_01366	2.14e-198	550.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_01366|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00524	411469.EUBHAL_01365	1.95e-227	628.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NIGDIANH_00525	411469.EUBHAL_01364	9.72e-183	509.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,25ZIZ@186806|Eubacteriaceae	186801|Clostridia	S	RelA SpoT domain protein	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NIGDIANH_00526	411469.EUBHAL_01363	2.28e-314	854.0	2DCT9@1|root,2ZF90@2|Bacteria,1W3HQ@1239|Firmicutes,2577Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00528	411469.EUBHAL_01361	2.12e-291	796.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,25VEY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NIGDIANH_00529	411469.EUBHAL_01360	2.58e-179	499.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,25W15@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NIGDIANH_00530	411469.EUBHAL_01359	1.13e-168	472.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,25VT5@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	glnQ1	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NIGDIANH_00531	411469.EUBHAL_01358	1.31e-141	401.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,24BKA@186801|Clostridia,25ZFK@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029,ko:K02030,ko:K10009	ko02010,map02010	M00234,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.10,3.A.1.3.14	-	-	BPD_transp_1
NIGDIANH_00532	411469.EUBHAL_01357	2.12e-181	505.0	COG0834@1|root,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,248UZ@186801|Clostridia,25ZFJ@186806|Eubacteriaceae	186801|Clostridia	ET	ABC transporter, substrate-binding protein, family 3	glnH1	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NIGDIANH_00533	411469.EUBHAL_02857	2.38e-76	227.0	2BW9N@1|root,32QZ7@2|Bacteria,1V8SR@1239|Firmicutes,24KPI@186801|Clostridia,25Z72@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00534	411469.EUBHAL_01616	2.67e-140	395.0	COG5423@1|root,COG5423@2|Bacteria,1V8BX@1239|Firmicutes,24JN8@186801|Clostridia,25WSV@186806|Eubacteriaceae	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NIGDIANH_00535	411469.EUBHAL_01617	2.44e-288	789.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,25VX1@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NIGDIANH_00536	411469.EUBHAL_01618	2.83e-151	425.0	COG2755@1|root,COG2755@2|Bacteria,1U5WX@1239|Firmicutes,25BIZ@186801|Clostridia,25WE4@186806|Eubacteriaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NIGDIANH_00539	411469.EUBHAL_01620	2.73e-205	568.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1VK50@1239|Firmicutes,25BJ0@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
NIGDIANH_00541	411469.EUBHAL_01622	0.0	866.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NIGDIANH_00542	411469.EUBHAL_01623	6e-235	647.0	COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,24C0T@186801|Clostridia,25ZAN@186806|Eubacteriaceae	186801|Clostridia	NU	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,Amidase_3,CW_7,CW_binding_1,Cu_amine_oxidN1,Glucosaminidase,PG_binding_1
NIGDIANH_00543	411469.EUBHAL_01624	3.3e-80	239.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia,25YVK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00544	411469.EUBHAL_01626	1.14e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00545	411469.EUBHAL_01627	0.0	986.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UVP@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_00546	411469.EUBHAL_00549	1.71e-96	290.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,25W97@186806|Eubacteriaceae	186801|Clostridia	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NIGDIANH_00548	411469.EUBHAL_00547	2.16e-100	293.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,25W8Q@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
NIGDIANH_00549	411469.EUBHAL_00546	0.0	2969.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,25VFS@186806|Eubacteriaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
NIGDIANH_00550	411469.EUBHAL_00545	9.77e-86	254.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,25X5Z@186806|Eubacteriaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00551	411469.EUBHAL_00544	0.0	1288.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,25UU5@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NIGDIANH_00552	411469.EUBHAL_00543	1.26e-248	684.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,25URK@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NIGDIANH_00553	411469.EUBHAL_00542	1.09e-62	192.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NIGDIANH_00554	411469.EUBHAL_02328	7.03e-32	121.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,25V3D@186806|Eubacteriaceae	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
NIGDIANH_00555	411469.EUBHAL_02161	0.0	903.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00556	411469.EUBHAL_02162	5.2e-224	617.0	2BHVM@1|root,32BZG@2|Bacteria,1UK71@1239|Firmicutes,25FNR@186801|Clostridia,25Z6A@186806|Eubacteriaceae	411469.EUBHAL_02162|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00557	411469.EUBHAL_02163	0.0	1145.0	COG0849@1|root,COG0849@2|Bacteria,1TQMU@1239|Firmicutes,24840@186801|Clostridia,25UW8@186806|Eubacteriaceae	186801|Clostridia	D	Diol dehydratase reactivase ATPase-like domain	dhaB4	-	-	-	-	-	-	-	-	-	-	-	DDR
NIGDIANH_00558	411469.EUBHAL_02164	2.73e-206	570.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,25YT5@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NIGDIANH_00559	411469.EUBHAL_02165	5.72e-157	439.0	COG2755@1|root,COG2755@2|Bacteria,1VEMX@1239|Firmicutes,24R36@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_lke
NIGDIANH_00560	411469.EUBHAL_02166	0.0	880.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NIGDIANH_00561	411469.EUBHAL_02167	1.29e-260	712.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,25V2T@186806|Eubacteriaceae	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NIGDIANH_00562	411469.EUBHAL_02168	0.0	1352.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,25V82@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NIGDIANH_00563	1280681.AUJZ01000017_gene456	1.54e-08	58.9	COG2340@1|root,COG4886@1|root,COG2340@2|Bacteria,COG4886@2|Bacteria,1V9HJ@1239|Firmicutes,24M7J@186801|Clostridia,4BXER@830|Butyrivibrio	186801|Clostridia	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,fn3
NIGDIANH_00564	411469.EUBHAL_01421	5.07e-125	355.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NIGDIANH_00566	411469.EUBHAL_01423	7.96e-163	457.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NIGDIANH_00568	411469.EUBHAL_01425	1.1e-157	459.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,25VCF@186806|Eubacteriaceae	186801|Clostridia	H	Cytoplasmic, score	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
NIGDIANH_00569	411469.EUBHAL_01425	1.66e-190	543.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1TPYV@1239|Firmicutes,248XC@186801|Clostridia,25VCF@186806|Eubacteriaceae	186801|Clostridia	H	Cytoplasmic, score	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
NIGDIANH_00570	411469.EUBHAL_01426	0.0	1566.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,25VQ1@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NIGDIANH_00571	411469.EUBHAL_01427	1.39e-228	628.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,25XA3@186806|Eubacteriaceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NIGDIANH_00572	411469.EUBHAL_01429	5.41e-254	698.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,25WXJ@186806|Eubacteriaceae	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NIGDIANH_00573	411469.EUBHAL_01430	4.98e-105	304.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,25WE8@186806|Eubacteriaceae	186801|Clostridia	E	acetolactate synthase, small	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NIGDIANH_00574	411469.EUBHAL_01065	7.42e-101	303.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VJ5@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00575	411469.EUBHAL_01065	7.05e-170	485.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VJ5@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00576	411469.EUBHAL_01064	1.36e-215	595.0	COG3965@1|root,COG3965@2|Bacteria,1UZ78@1239|Firmicutes,24BM7@186801|Clostridia,25WR8@186806|Eubacteriaceae	186801|Clostridia	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
NIGDIANH_00578	411469.EUBHAL_01061	7.63e-271	743.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,25V8Y@186806|Eubacteriaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
NIGDIANH_00579	411469.EUBHAL_01060	9.43e-225	620.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,25VC0@186806|Eubacteriaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
NIGDIANH_00580	411469.EUBHAL_01059	0.0	972.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VH2@186806|Eubacteriaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
NIGDIANH_00581	411469.EUBHAL_01058	6.49e-290	790.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,25VQH@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
NIGDIANH_00582	411469.EUBHAL_01057	5.41e-84	247.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,25WZB@186806|Eubacteriaceae	186801|Clostridia	C	superoxide reductase	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
NIGDIANH_00583	411469.EUBHAL_01054	9.75e-25	95.5	COG1846@1|root,COG1846@2|Bacteria,1VBT5@1239|Firmicutes,24MVP@186801|Clostridia,25XI2@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_27,MarR,MarR_2
NIGDIANH_00584	411469.EUBHAL_01053	8.09e-301	823.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25V6E@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00585	411469.EUBHAL_00865	3.68e-97	282.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,25XHZ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NIGDIANH_00586	411469.EUBHAL_00864	1.06e-149	421.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,25V2P@186806|Eubacteriaceae	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NIGDIANH_00587	411469.EUBHAL_00862	6.03e-177	494.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,25XH8@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator, DeoR family	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NIGDIANH_00588	411469.EUBHAL_00860	5.9e-313	854.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,25VSJ@186806|Eubacteriaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	uraA	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
NIGDIANH_00589	411469.EUBHAL_00858	2.71e-95	278.0	COG1671@1|root,COG1671@2|Bacteria,1V9Z0@1239|Firmicutes,24HPW@186801|Clostridia,25WGU@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0178 family	-	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
NIGDIANH_00590	411469.EUBHAL_02754	1.8e-219	605.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,25VAS@186806|Eubacteriaceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NIGDIANH_00591	411469.EUBHAL_02753	1.28e-255	700.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,25UZ7@186806|Eubacteriaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
NIGDIANH_00592	411469.EUBHAL_02752	2.06e-38	128.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,25XUP@186806|Eubacteriaceae	186801|Clostridia	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
NIGDIANH_00593	411469.EUBHAL_02751	0.0	995.0	COG1686@1|root,COG1686@2|Bacteria,1V50I@1239|Firmicutes,24I5G@186801|Clostridia,25YWM@186806|Eubacteriaceae	186801|Clostridia	M	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
NIGDIANH_00594	411469.EUBHAL_02750	1.92e-199	551.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,25XC0@186806|Eubacteriaceae	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NIGDIANH_00595	411469.EUBHAL_02749	4.84e-230	637.0	COG4198@1|root,COG4198@2|Bacteria,1TQ52@1239|Firmicutes,24985@186801|Clostridia,25VHP@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NIGDIANH_00596	411469.EUBHAL_00815	9.96e-141	397.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_00597	411469.EUBHAL_00814	1.78e-126	360.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia,25XES@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NIGDIANH_00598	411469.EUBHAL_00813	1.18e-72	218.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,25WWK@186806|Eubacteriaceae	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
NIGDIANH_00599	411460.RUMTOR_00305	1.22e-118	345.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,3XYU1@572511|Blautia	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
NIGDIANH_00600	411469.EUBHAL_00810	2.94e-200	554.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,25VQP@186806|Eubacteriaceae	186801|Clostridia	P	Part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NIGDIANH_00601	411469.EUBHAL_00809	1.61e-184	514.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,24A4J@186801|Clostridia,25VX4@186806|Eubacteriaceae	186801|Clostridia	P	Cobalt transport protein	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NIGDIANH_00602	411469.EUBHAL_00808	0.0	1494.0	COG1595@1|root,COG1595@2|Bacteria,1V8Z0@1239|Firmicutes,24KTC@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,WG_beta_rep,zinc_ribbon_2
NIGDIANH_00603	411469.EUBHAL_00807	2.83e-175	487.0	COG1011@1|root,COG1011@2|Bacteria,1V3WC@1239|Firmicutes,24J13@186801|Clostridia,25XR4@186806|Eubacteriaceae	186801|Clostridia	S	HAD hydrolase, family IA, variant 1	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
NIGDIANH_00604	1280681.AUJZ01000012_gene1099	2.14e-05	53.1	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4091,DUF5057,FIVAR
NIGDIANH_00605	1280671.AUJH01000004_gene3009	4.47e-08	63.5	COG4886@1|root,COG4886@2|Bacteria,1W0QU@1239|Firmicutes,253ET@186801|Clostridia,4C1TS@830|Butyrivibrio	186801|Clostridia	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
NIGDIANH_00608	411459.RUMOBE_03533	6.84e-112	333.0	2F80K@1|root,340E6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00611	363253.LIB024	1.03e-85	262.0	COG1192@1|root,COG1192@2|Bacteria,1Q9Y2@1224|Proteobacteria,430A0@68525|delta/epsilon subdivisions,2WVJJ@28221|Deltaproteobacteria,2MFX1@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NIGDIANH_00617	1408323.JQKK01000038_gene2569	4.33e-97	289.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia,27MDN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NIGDIANH_00618	411469.EUBHAL_02433	0.0	978.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,25ZUM@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NIGDIANH_00619	411469.EUBHAL_02432	4.2e-139	393.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_00620	411469.EUBHAL_02431	1.33e-301	822.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,25YEH@186806|Eubacteriaceae	186801|Clostridia	H	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NIGDIANH_00621	411469.EUBHAL_02430	7.89e-268	733.0	COG1454@1|root,COG1454@2|Bacteria,1UY3E@1239|Firmicutes,25E9A@186801|Clostridia,25W00@186806|Eubacteriaceae	186801|Clostridia	C	Cytoplasmic, score 9.98	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NIGDIANH_00622	411469.EUBHAL_02428	1.66e-290	792.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,25X5H@186806|Eubacteriaceae	186801|Clostridia	QT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NIGDIANH_00623	411469.EUBHAL_02427	4.48e-98	285.0	COG4506@1|root,COG4506@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NIGDIANH_00624	411469.EUBHAL_02426	8.01e-254	696.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,25V8G@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NIGDIANH_00625	411469.EUBHAL_02425	2.5e-230	633.0	COG0613@1|root,COG0613@2|Bacteria,1UH35@1239|Firmicutes,248HV@186801|Clostridia,25V59@186806|Eubacteriaceae	186801|Clostridia	G	DNA polymerase alpha chain like domain	-	-	3.1.3.97,4.1.2.13	ko:K01624,ko:K07053	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R00188,R01068,R01070,R01829,R02568,R11188	RC00078,RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
NIGDIANH_00626	411469.EUBHAL_02424	2.69e-193	537.0	COG0191@1|root,COG0191@2|Bacteria,1V28V@1239|Firmicutes,24GYP@186801|Clostridia,25WBM@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NIGDIANH_00627	411469.EUBHAL_01549	8.67e-143	404.0	COG1802@1|root,COG1802@2|Bacteria,1TS3S@1239|Firmicutes,24DBG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NIGDIANH_00628	411469.EUBHAL_01548	3.55e-139	394.0	COG1802@1|root,COG1802@2|Bacteria,1VH73@1239|Firmicutes,24SWG@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NIGDIANH_00629	411469.EUBHAL_03197	1.3e-95	278.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,25X1S@186806|Eubacteriaceae	186801|Clostridia	S	metal-dependent protease of the PAD1 JAB1 superfamily	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
NIGDIANH_00630	411469.EUBHAL_03198	7e-126	361.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
NIGDIANH_00631	411469.EUBHAL_03198	5.05e-14	70.5	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,25V2C@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
NIGDIANH_00632	411469.EUBHAL_03199	2.49e-39	130.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,25XIY@186806|Eubacteriaceae	186801|Clostridia	H	THIamine biosynthesis	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NIGDIANH_00633	411469.EUBHAL_03200	1.27e-66	202.0	COG0526@1|root,COG0526@2|Bacteria,1TTVH@1239|Firmicutes,25N66@186801|Clostridia,25Z55@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NIGDIANH_00634	411469.EUBHAL_03201	1.61e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,25XMJ@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NIGDIANH_00635	411469.EUBHAL_03202	3.67e-194	540.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,25UZE@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
NIGDIANH_00636	411469.EUBHAL_03203	3.49e-290	793.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,25VC2@186806|Eubacteriaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NIGDIANH_00637	411469.EUBHAL_03204	0.0	1027.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,25VWU@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NIGDIANH_00638	411469.EUBHAL_03205	1.81e-221	610.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NIGDIANH_00639	411469.EUBHAL_03206	6.23e-76	226.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
NIGDIANH_00640	411469.EUBHAL_03207	0.0	1139.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,25VSD@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NIGDIANH_00641	411469.EUBHAL_01231	1.33e-181	505.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,25W0K@186806|Eubacteriaceae	186801|Clostridia	J	RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
NIGDIANH_00642	411469.EUBHAL_01230	4.87e-123	350.0	COG1309@1|root,COG1309@2|Bacteria,1V890@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NIGDIANH_00643	411469.EUBHAL_01229	7.24e-283	774.0	COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia,25W2Z@186806|Eubacteriaceae	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NIGDIANH_00644	411469.EUBHAL_01228	6.14e-204	565.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,25V6R@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NIGDIANH_00645	411469.EUBHAL_01227	1.42e-223	618.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,25WDJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00646	1410632.JHWW01000006_gene694	2.03e-11	64.7	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00647	411469.EUBHAL_01225	2.76e-99	289.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,25W38@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NIGDIANH_00648	411469.EUBHAL_01224	1.82e-229	631.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,25VHB@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NIGDIANH_00649	411469.EUBHAL_01223	3.99e-183	509.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,25VB2@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NIGDIANH_00650	411469.EUBHAL_01222	7.86e-77	229.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,25WWT@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00651	411469.EUBHAL_01221	2.05e-231	637.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,25W5K@186806|Eubacteriaceae	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NIGDIANH_00652	411469.EUBHAL_01220	2.72e-237	652.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,25UXW@186806|Eubacteriaceae	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12430	OTCace,OTCace_N
NIGDIANH_00653	411469.EUBHAL_01029	2.78e-43	153.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,25UY0@186806|Eubacteriaceae	186801|Clostridia	E	dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NIGDIANH_00654	411469.EUBHAL_01029	1.88e-267	737.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,25UY0@186806|Eubacteriaceae	186801|Clostridia	E	dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NIGDIANH_00655	411469.EUBHAL_01030	1.26e-135	390.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,25V74@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NIGDIANH_00656	411469.EUBHAL_01030	1.7e-79	243.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,25V74@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NIGDIANH_00657	411469.EUBHAL_01031	0.0	1291.0	COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,24CD5@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	-	-	-	ko:K13274,ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Big_2,CW_binding_2,ChW,Peptidase_S8,SLH
NIGDIANH_00658	411469.EUBHAL_01032	2.07e-149	420.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,25W41@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
NIGDIANH_00659	411469.EUBHAL_01034	0.0	913.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia,25VHN@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
NIGDIANH_00660	411469.EUBHAL_01035	0.0	1300.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,25VE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00661	1095750.HMPREF9970_0730	1.33e-43	142.0	2DMVX@1|root,32U0C@2|Bacteria,1VBJ1@1239|Firmicutes,25PPR@186801|Clostridia,1HWFN@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00662	610130.Closa_3692	4.21e-94	276.0	2DMYF@1|root,32UDM@2|Bacteria,1V0JJ@1239|Firmicutes,24DJ4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
NIGDIANH_00663	411469.EUBHAL_02192	9.53e-20	84.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NIGDIANH_00664	411469.EUBHAL_02830	8.09e-96	284.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,Response_reg,dCache_1
NIGDIANH_00666	411469.EUBHAL_02840	3.87e-237	652.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,25ZUP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
NIGDIANH_00667	411469.EUBHAL_02841	0.0	1001.0	COG1620@1|root,COG1620@2|Bacteria,1TQNM@1239|Firmicutes,2482V@186801|Clostridia,25VC4@186806|Eubacteriaceae	186801|Clostridia	C	L-lactate permease	-	-	-	ko:K03303	-	-	-	-	ko00000,ko02000	2.A.14	-	-	Lactate_perm
NIGDIANH_00668	411469.EUBHAL_02842	8.46e-205	566.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,25WJF@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
NIGDIANH_00669	411469.EUBHAL_02843	6.7e-124	352.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NIGDIANH_00670	411469.EUBHAL_02844	1.45e-85	252.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,25ZJH@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NIGDIANH_00671	411469.EUBHAL_02845	8.55e-214	589.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,25VP5@186806|Eubacteriaceae	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NIGDIANH_00672	411469.EUBHAL_01513	3.5e-179	506.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,25V91@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NIGDIANH_00673	411469.EUBHAL_01514	0.0	1394.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,25V9J@186806|Eubacteriaceae	186801|Clostridia	S	Glutamate--ammonia ligase, catalytic domain protein	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NIGDIANH_00674	411469.EUBHAL_01515	1.06e-61	201.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NIGDIANH_00675	411469.EUBHAL_01515	2.45e-224	623.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,25V6Z@186806|Eubacteriaceae	186801|Clostridia	H	Folylpolyglutamate synthase	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NIGDIANH_00676	411469.EUBHAL_01516	3.56e-192	533.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,25V52@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
NIGDIANH_00677	411469.EUBHAL_01517	8.43e-198	548.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,25W0A@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
NIGDIANH_00678	411469.EUBHAL_01518	1.23e-273	748.0	COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,25VRD@186806|Eubacteriaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NIGDIANH_00679	411469.EUBHAL_01519	4e-203	585.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25VK6@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NIGDIANH_00680	411469.EUBHAL_00889	2.15e-237	654.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,25X44@186806|Eubacteriaceae	186801|Clostridia	S	Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
NIGDIANH_00681	411469.EUBHAL_00890	0.0	1043.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K08777	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FHA
NIGDIANH_00683	411469.EUBHAL_00892	2.94e-221	610.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,25XBZ@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NIGDIANH_00684	411469.EUBHAL_00893	0.0	964.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,25WG5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00685	658086.HMPREF0994_06764	2.59e-11	60.5	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
NIGDIANH_00686	411469.EUBHAL_00895	1.45e-298	817.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,25WIH@186806|Eubacteriaceae	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NIGDIANH_00687	411469.EUBHAL_00896	6.98e-111	323.0	COG4965@1|root,COG4965@2|Bacteria	2|Bacteria	U	Type ii secretion system	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NIGDIANH_00688	411469.EUBHAL_00897	1.01e-248	685.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,25US5@186806|Eubacteriaceae	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NIGDIANH_00689	411469.EUBHAL_01414	0.0	1170.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NIGDIANH_00690	411469.EUBHAL_01413	5.5e-161	450.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
NIGDIANH_00691	411469.EUBHAL_01412	6.65e-153	429.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia,25W9Z@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
NIGDIANH_00692	411469.EUBHAL_01410	4.04e-263	721.0	2DBS4@1|root,2ZAPG@2|Bacteria,1V2EV@1239|Firmicutes,24F58@186801|Clostridia,25W4K@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00693	411469.EUBHAL_01409	1.32e-205	572.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	iap	-	-	-	-	-	-	-	-	-	-	-	LysM,NLPC_P60,SH3_3
NIGDIANH_00694	411469.EUBHAL_01408	9.86e-210	581.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NIGDIANH_00695	411469.EUBHAL_01407	3.88e-123	350.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NIGDIANH_00696	411469.EUBHAL_01406	2.37e-60	189.0	COG0494@1|root,COG0494@2|Bacteria,1V42T@1239|Firmicutes,24ICB@186801|Clostridia	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NIGDIANH_00697	411469.EUBHAL_03049	0.0	919.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,25V5J@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NIGDIANH_00698	411469.EUBHAL_03051	8.01e-202	560.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,25V4F@186806|Eubacteriaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NIGDIANH_00699	411469.EUBHAL_03053	4.4e-180	507.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,25XYB@186806|Eubacteriaceae	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NIGDIANH_00700	411469.EUBHAL_03054	6.08e-129	368.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NIGDIANH_00701	411469.EUBHAL_03055	2.49e-73	219.0	COG1695@1|root,COG1695@2|Bacteria,1VA8W@1239|Firmicutes,24NE2@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NIGDIANH_00702	411469.EUBHAL_03056	2.75e-79	236.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,25X79@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NIGDIANH_00703	411469.EUBHAL_03057	4.54e-210	581.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,25VUY@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase component	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NIGDIANH_00704	411469.EUBHAL_03058	0.0	1231.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
NIGDIANH_00705	411469.EUBHAL_01585	5.19e-144	407.0	COG3911@1|root,COG3911@2|Bacteria	2|Bacteria	K	COG3911 Predicted ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
NIGDIANH_00706	411469.EUBHAL_01586	1.33e-193	538.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
NIGDIANH_00708	411469.EUBHAL_01588	1.18e-72	218.0	2DSE8@1|root,33FSA@2|Bacteria,1UK72@1239|Firmicutes,25FNS@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NIGDIANH_00709	411469.EUBHAL_01589	2.88e-272	747.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,25UR9@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NIGDIANH_00710	411469.EUBHAL_01590	7.07e-219	602.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,25W43@186806|Eubacteriaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
NIGDIANH_00711	411469.EUBHAL_01591	0.0	2083.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia,25V9F@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NIGDIANH_00712	411469.EUBHAL_02276	6.63e-186	518.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,25V2Z@186806|Eubacteriaceae	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
NIGDIANH_00713	411469.EUBHAL_02277	4.39e-139	393.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NIGDIANH_00714	411469.EUBHAL_02278	6.45e-144	405.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NIGDIANH_00715	411469.EUBHAL_02279	1.01e-173	485.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,25VNF@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NIGDIANH_00716	411469.EUBHAL_02280	3.69e-81	240.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,25X8A@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NIGDIANH_00717	411469.EUBHAL_02281	6.15e-203	561.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,25VJY@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NIGDIANH_00718	411469.EUBHAL_02282	0.0	890.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,25VHQ@186806|Eubacteriaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NIGDIANH_00719	411469.EUBHAL_02283	5.03e-314	856.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,25VCW@186806|Eubacteriaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NIGDIANH_00720	411469.EUBHAL_02284	2.51e-145	410.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,25WH3@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NIGDIANH_00721	411469.EUBHAL_02285	0.0	951.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,25V5V@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
NIGDIANH_00722	411469.EUBHAL_01784	0.0	2107.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_3,Cna_B,Collagen_bind,DUF5011,Gram_pos_anchor,MucBP,SdrD_B
NIGDIANH_00724	411469.EUBHAL_01786	2.71e-190	528.0	COG1028@1|root,COG1028@2|Bacteria,1TRYD@1239|Firmicutes,248RG@186801|Clostridia,25UQZ@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NIGDIANH_00725	411469.EUBHAL_01788	4.67e-127	361.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NIGDIANH_00726	411469.EUBHAL_01789	1.63e-194	540.0	29Q1W@1|root,30B0G@2|Bacteria,1W3VE@1239|Firmicutes,2551C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00727	411469.EUBHAL_01790	0.0	1033.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NIGDIANH_00728	411469.EUBHAL_03021	3.39e-169	477.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,25V5Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NIGDIANH_00729	411469.EUBHAL_03022	1.04e-189	528.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,25W19@186806|Eubacteriaceae	186801|Clostridia	M	Small conductance mechanosensitive ion channel, MscS family	mscS	-	-	ko:K03442,ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.2,1.A.23.3	-	-	MS_channel,TM_helix
NIGDIANH_00730	411469.EUBHAL_03023	6.97e-301	823.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,25VNG@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_00731	411469.EUBHAL_03024	7.41e-254	696.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,25VWE@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NIGDIANH_00732	411469.EUBHAL_03025	0.0	874.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NIGDIANH_00733	411469.EUBHAL_03026	0.0	904.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,25VGK@186806|Eubacteriaceae	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NIGDIANH_00734	411469.EUBHAL_03028	2.12e-226	624.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,25WBA@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NIGDIANH_00735	411469.EUBHAL_03029	8.56e-178	496.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,25W31@186806|Eubacteriaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NIGDIANH_00736	411469.EUBHAL_02327	0.0	1036.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,25VM7@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NIGDIANH_00737	411469.EUBHAL_02326	1.1e-170	476.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,25WSE@186806|Eubacteriaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NIGDIANH_00738	411469.EUBHAL_02325	9.03e-174	484.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,25VEM@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_00739	411469.EUBHAL_02323	5.92e-280	766.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,25USF@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
NIGDIANH_00740	411469.EUBHAL_02322	8.56e-90	263.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,25W85@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
NIGDIANH_00741	411469.EUBHAL_02321	1.15e-198	550.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,25URM@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
NIGDIANH_00742	411469.EUBHAL_02319	1.69e-193	537.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,25V3K@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
NIGDIANH_00743	411469.EUBHAL_02318	4.36e-204	564.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,25W39@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
NIGDIANH_00746	478749.BRYFOR_08557	4.53e-86	299.0	2DKX6@1|root,30QMZ@2|Bacteria,1V66W@1239|Firmicutes,24HHF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00747	478749.BRYFOR_08556	1.23e-87	278.0	COG3344@1|root,COG3344@2|Bacteria,1V9Q7@1239|Firmicutes,25C60@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NIGDIANH_00749	411461.DORFOR_00727	1.46e-18	78.2	2EBRI@1|root,335RF@2|Bacteria,1VG54@1239|Firmicutes,24TJY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00752	1151292.QEW_0990	8.32e-41	140.0	COG4824@1|root,COG4824@2|Bacteria,1VE24@1239|Firmicutes,24MY4@186801|Clostridia	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NIGDIANH_00757	411469.EUBHAL_00070	7.43e-277	758.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
NIGDIANH_00758	411469.EUBHAL_00071	9.39e-184	511.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
NIGDIANH_00759	411469.EUBHAL_00072	7.19e-197	546.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,25V6P@186806|Eubacteriaceae	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
NIGDIANH_00760	411469.EUBHAL_00073	1.85e-266	731.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
NIGDIANH_00761	411469.EUBHAL_00074	9.78e-186	516.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03521,ko:K22431	-	-	-	-	ko00000,ko01000	-	-	-	ETF
NIGDIANH_00762	411469.EUBHAL_00075	1.57e-245	675.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
NIGDIANH_00764	411469.EUBHAL_00351	9.23e-65	197.0	COG4842@1|root,COG4842@2|Bacteria,1VGZJ@1239|Firmicutes,24SEZ@186801|Clostridia,25XDQ@186806|Eubacteriaceae	186801|Clostridia	S	Proteins of 100 residues with WXG	-	-	-	-	-	-	-	-	-	-	-	-	WXG100
NIGDIANH_00765	411469.EUBHAL_01140	0.0	894.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,25VWZ@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NIGDIANH_00766	411469.EUBHAL_00221	5.31e-55	172.0	COG2002@1|root,COG2002@2|Bacteria,1VA3H@1239|Firmicutes,24MN7@186801|Clostridia,25XG6@186806|Eubacteriaceae	186801|Clostridia	K	SpoVT / AbrB like domain	abrB	-	-	ko:K06284	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin
NIGDIANH_00767	411469.EUBHAL_00222	2.97e-208	575.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,25UUW@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NIGDIANH_00768	411469.EUBHAL_00223	0.0	1103.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
NIGDIANH_00769	411469.EUBHAL_00224	5.01e-58	194.0	COG0768@1|root,COG0768@2|Bacteria,1UJPW@1239|Firmicutes,25F83@186801|Clostridia,25XIT@186806|Eubacteriaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
NIGDIANH_00770	411469.EUBHAL_00224	1.6e-253	706.0	COG0768@1|root,COG0768@2|Bacteria,1UJPW@1239|Firmicutes,25F83@186801|Clostridia,25XIT@186806|Eubacteriaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
NIGDIANH_00771	411469.EUBHAL_00225	1.1e-165	463.0	COG1694@1|root,COG3956@2|Bacteria,1TPK1@1239|Firmicutes,247XM@186801|Clostridia,25VUV@186806|Eubacteriaceae	186801|Clostridia	S	MazG family	mazG	-	3.6.1.66	ko:K02428,ko:K02499	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG,TP_methylase
NIGDIANH_00772	411469.EUBHAL_00227	9.68e-110	316.0	COG1846@1|root,COG1846@2|Bacteria,1V8EW@1239|Firmicutes,24RW7@186801|Clostridia,25XTG@186806|Eubacteriaceae	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NIGDIANH_00773	411469.EUBHAL_00228	7.41e-197	553.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NIGDIANH_00774	411469.EUBHAL_02335	3.84e-232	637.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,25VBU@186806|Eubacteriaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
NIGDIANH_00775	411469.EUBHAL_02336	0.0	1265.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,25UXA@186806|Eubacteriaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NIGDIANH_00776	411469.EUBHAL_02337	5.7e-192	533.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,25W0T@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NIGDIANH_00777	411469.EUBHAL_02338	1.28e-85	252.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,25WV6@186806|Eubacteriaceae	186801|Clostridia	S	THIoesterase	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
NIGDIANH_00778	411469.EUBHAL_02984	3.25e-308	843.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NIGDIANH_00779	411469.EUBHAL_02983	2.37e-249	684.0	COG1063@1|root,COG1063@2|Bacteria,1TQSR@1239|Firmicutes,248KM@186801|Clostridia,25VBS@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate	-	-	1.1.1.405	ko:K05352	ko00040,ko01100,map00040,map01100	-	R01525	RC00089	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N,Glu_dehyd_C
NIGDIANH_00780	411469.EUBHAL_02982	4.52e-12	64.3	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
NIGDIANH_00781	411469.EUBHAL_02982	9.7e-134	382.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.40,2.7.7.60	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	M00096	R02921,R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
NIGDIANH_00782	411469.EUBHAL_01121	3.27e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25VN3@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NIGDIANH_00783	411469.EUBHAL_01120	3.98e-92	270.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,25WDI@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NIGDIANH_00784	411469.EUBHAL_01119	2.15e-121	346.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,25VW0@186806|Eubacteriaceae	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NIGDIANH_00785	411469.EUBHAL_01118	1.23e-35	121.0	COG0690@1|root,COG0690@2|Bacteria,1U4FZ@1239|Firmicutes,25NAF@186801|Clostridia,25XZS@186806|Eubacteriaceae	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NIGDIANH_00786	411469.EUBHAL_01115	2.37e-104	301.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
NIGDIANH_00787	411469.EUBHAL_01114	1.4e-203	562.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,25WN6@186806|Eubacteriaceae	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NIGDIANH_00788	411469.EUBHAL_01113	0.0	1444.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,25UUZ@186806|Eubacteriaceae	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NIGDIANH_00789	411469.EUBHAL_01112	4.41e-222	613.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,25UZP@186806|Eubacteriaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NIGDIANH_00790	411469.EUBHAL_01111	8.1e-44	142.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,25XFQ@186806|Eubacteriaceae	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NIGDIANH_00791	411469.EUBHAL_01110	2.68e-115	330.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,25X07@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NIGDIANH_00792	411469.EUBHAL_00142	2.1e-238	657.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,25VAU@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NIGDIANH_00793	411469.EUBHAL_00143	9.02e-163	456.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,25UYS@186806|Eubacteriaceae	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NIGDIANH_00794	411469.EUBHAL_00144	0.0	1695.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,25V6U@186806|Eubacteriaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
NIGDIANH_00795	411469.EUBHAL_00145	1.08e-215	596.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,25USB@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NIGDIANH_00796	411469.EUBHAL_00146	4.87e-286	783.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,25UV8@186806|Eubacteriaceae	186801|Clostridia	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NIGDIANH_00797	411469.EUBHAL_02805	5.03e-40	134.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,25X2B@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NIGDIANH_00798	411469.EUBHAL_02807	2.76e-286	783.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,25UQG@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
NIGDIANH_00799	411469.EUBHAL_02808	3.15e-277	758.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25V3Y@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NIGDIANH_00800	500632.CLONEX_02563	0.0	1134.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia	186801|Clostridia	V	ATPase family associated with various cellular activities (AAA)	mcrB	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5,EVE,Mrr_N
NIGDIANH_00801	500632.CLONEX_02562	2.52e-208	580.0	COG4268@1|root,COG4268@2|Bacteria,1TQJI@1239|Firmicutes,24AAV@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	mcrC	-	-	ko:K19147	-	-	-	-	ko00000,ko02048	-	-	-	McrBC
NIGDIANH_00803	411469.EUBHAL_02628	7.06e-36	121.0	COG1724@1|root,COG1724@2|Bacteria,1VGR5@1239|Firmicutes,24QWD@186801|Clostridia	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
NIGDIANH_00804	411469.EUBHAL_02629	3.82e-91	266.0	COG1598@1|root,COG1598@2|Bacteria,1VAKM@1239|Firmicutes,24K5X@186801|Clostridia,25XVW@186806|Eubacteriaceae	186801|Clostridia	S	Toxin-antitoxin system, antitoxin component, HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
NIGDIANH_00805	411469.EUBHAL_02630	0.0	927.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,25V0R@186806|Eubacteriaceae	186801|Clostridia	C	Conserved carboxylase domain	pycB	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NIGDIANH_00806	1232447.BAHW02000027_gene1809	1.63e-60	190.0	COG2893@1|root,COG2893@2|Bacteria,1VBC1@1239|Firmicutes,24PAX@186801|Clostridia	186801|Clostridia	G	PTS system fructose IIA component	-	-	-	ko:K02744	ko00052,ko02060,map00052,map02060	M00277,M00287	R08366,R08367	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1.4,4.A.6.1.5	-	-	EIIA-man
NIGDIANH_00807	1232447.BAHW02000027_gene1810	3.26e-168	487.0	COG1653@1|root,COG1653@2|Bacteria,1TPX9@1239|Firmicutes,24DGD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NIGDIANH_00808	1232447.BAHW02000027_gene1811	9e-99	293.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,269AP@186813|unclassified Clostridiales	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
NIGDIANH_00809	1232447.BAHW02000027_gene1812	5.29e-136	404.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,dCache_1
NIGDIANH_00810	1232447.BAHW02000027_gene1813	1.49e-120	357.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,249ZI@186801|Clostridia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NIGDIANH_00812	411469.EUBHAL_02825	1.12e-292	797.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,25WKM@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
NIGDIANH_00813	411469.EUBHAL_02827	8.18e-215	594.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,25VYY@186806|Eubacteriaceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NIGDIANH_00814	411469.EUBHAL_02828	2.85e-103	298.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25WC5@186806|Eubacteriaceae	186801|Clostridia	P	Psort location Cytoplasmic, score	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NIGDIANH_00815	411469.EUBHAL_01728	2.98e-20	89.4	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NIGDIANH_00816	411469.EUBHAL_01940	4.52e-112	322.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,25WPU@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NIGDIANH_00817	411469.EUBHAL_01939	1.82e-225	620.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,25VM9@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NIGDIANH_00818	411469.EUBHAL_01938	1.22e-308	840.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,25VA4@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NIGDIANH_00819	411469.EUBHAL_01937	0.0	1407.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,25UZY@186806|Eubacteriaceae	186801|Clostridia	E	Leucyl aminopeptidase (Aminopeptidase T)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
NIGDIANH_00821	411469.EUBHAL_01935	8.64e-112	321.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,25XKJ@186806|Eubacteriaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NIGDIANH_00822	1235798.C817_02915	6.38e-08	50.8	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,27VXW@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00823	411469.EUBHAL_01932	2.47e-159	447.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,25V0N@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NIGDIANH_00824	411469.EUBHAL_01931	4.09e-218	601.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,25USG@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NIGDIANH_00825	411469.EUBHAL_01930	8.91e-42	143.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,25V0Z@186806|Eubacteriaceae	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NIGDIANH_00826	411469.EUBHAL_01802	4.7e-194	537.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia,25ZHT@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_00827	411469.EUBHAL_01803	5.1e-285	781.0	COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	mglB	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NIGDIANH_00828	411469.EUBHAL_01804	8.03e-218	610.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25VXF@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	mglA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
NIGDIANH_00829	411469.EUBHAL_01804	2.44e-120	356.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,25VXF@186806|Eubacteriaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	mglA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
NIGDIANH_00830	411469.EUBHAL_01805	0.0	1030.0	COG3064@1|root,COG4211@1|root,COG3064@2|Bacteria,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,25VS7@186806|Eubacteriaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
NIGDIANH_00831	411469.EUBHAL_01806	0.0	1040.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,25V1U@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NIGDIANH_00833	411469.EUBHAL_00584	1.11e-179	499.0	2A0UZ@1|root,30NZW@2|Bacteria,1V4U0@1239|Firmicutes,24F0B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00834	411469.EUBHAL_00585	2.01e-109	316.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,25WAH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
NIGDIANH_00835	411469.EUBHAL_00586	9.25e-144	406.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,25W3R@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
NIGDIANH_00836	411469.EUBHAL_00588	1.99e-273	748.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,25VRF@186806|Eubacteriaceae	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NIGDIANH_00837	411469.EUBHAL_00589	0.0	1259.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
NIGDIANH_00838	411469.EUBHAL_00590	6.12e-30	114.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,LRR_5
NIGDIANH_00839	411469.EUBHAL_00590	5.53e-161	456.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,LRR_5
NIGDIANH_00840	411469.EUBHAL_00591	1.83e-195	542.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,25V9Q@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NIGDIANH_00841	411469.EUBHAL_00592	3.12e-89	266.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,25UWI@186806|Eubacteriaceae	186801|Clostridia	S	Methyltransferase small domain	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NIGDIANH_00842	411469.EUBHAL_00110	2.08e-152	428.0	COG1309@1|root,COG1309@2|Bacteria,1UR73@1239|Firmicutes,25BIY@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_00843	411469.EUBHAL_00108	1.11e-52	166.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,25X7H@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NIGDIANH_00844	411469.EUBHAL_00107	0.0	870.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25V7V@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NIGDIANH_00845	411469.EUBHAL_02658	6.32e-169	472.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,25ZHW@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NIGDIANH_00846	411469.EUBHAL_02657	6.1e-255	698.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,25V0S@186806|Eubacteriaceae	186801|Clostridia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
NIGDIANH_00847	411469.EUBHAL_02656	8.24e-146	414.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,25WH8@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NIGDIANH_00848	411469.EUBHAL_02655	1.86e-63	194.0	COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,24MY3@186801|Clostridia,25XHN@186806|Eubacteriaceae	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
NIGDIANH_00849	411469.EUBHAL_02654	0.0	890.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25UUS@186806|Eubacteriaceae	186801|Clostridia	E	amino acid carrier protein	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NIGDIANH_00850	411469.EUBHAL_03168	0.0	1299.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,25VAX@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NIGDIANH_00851	411469.EUBHAL_03167	7.9e-141	403.0	COG4509@1|root,COG4509@2|Bacteria,1V7UG@1239|Firmicutes,24KBR@186801|Clostridia,25WQP@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NIGDIANH_00852	411469.EUBHAL_03166	2.99e-122	349.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,25WWS@186806|Eubacteriaceae	186801|Clostridia	H	Adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NIGDIANH_00853	411469.EUBHAL_03165	4.4e-177	494.0	2E4FW@1|root,32ZB1@2|Bacteria,1VES0@1239|Firmicutes,24TIF@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1189
NIGDIANH_00854	411469.EUBHAL_03164	1.01e-123	353.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,25WM7@186806|Eubacteriaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NIGDIANH_00855	411469.EUBHAL_03163	1.94e-109	315.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,25WPY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
NIGDIANH_00856	411469.EUBHAL_03162	0.0	882.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,25VRN@186806|Eubacteriaceae	186801|Clostridia	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NIGDIANH_00857	411469.EUBHAL_03082	0.0	1446.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,25UZD@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NIGDIANH_00858	411469.EUBHAL_03081	0.0	1263.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,25UT9@186806|Eubacteriaceae	186801|Clostridia	L	DNA gyrase	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NIGDIANH_00859	411469.EUBHAL_03080	8.11e-166	462.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24GJJ@186801|Clostridia,25W8M@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NIGDIANH_00860	411469.EUBHAL_03079	0.0	907.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,25VJN@186806|Eubacteriaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NIGDIANH_00861	411469.EUBHAL_03078	4.9e-303	825.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NIGDIANH_00862	411469.EUBHAL_02496	9.52e-62	189.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,25WUP@186806|Eubacteriaceae	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
NIGDIANH_00863	411469.EUBHAL_02498	0.0	1374.0	COG0193@1|root,COG1887@1|root,COG0193@2|Bacteria,COG1887@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,25W6U@186806|Eubacteriaceae	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NIGDIANH_00864	411469.EUBHAL_02499	0.0	2263.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,25V0T@186806|Eubacteriaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NIGDIANH_00865	411469.EUBHAL_02500	2.68e-221	617.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,25WBW@186806|Eubacteriaceae	186801|Clostridia	O	Parvulin-like peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NIGDIANH_00866	180332.JTGN01000005_gene2952	4.68e-07	64.3	COG2382@1|root,COG3325@1|root,COG3387@1|root,COG5492@1|root,COG2382@2|Bacteria,COG3325@2|Bacteria,COG3387@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.40,3.2.1.55	ko:K05989,ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N,Big_2,DUF4849
NIGDIANH_00867	1395513.P343_11555	3.46e-17	90.9	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4IQDH@91061|Bacilli	91061|Bacilli	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
NIGDIANH_00868	411469.EUBHAL_01977	6.4e-281	768.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,25VIZ@186806|Eubacteriaceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
NIGDIANH_00869	411469.EUBHAL_01976	1.97e-159	447.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,25WH6@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NIGDIANH_00870	411469.EUBHAL_01975	1.05e-180	503.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,25UVS@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NIGDIANH_00871	411469.EUBHAL_01974	2.37e-134	380.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,25VZ2@186806|Eubacteriaceae	186801|Clostridia	EH	Peptidase C26	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NIGDIANH_00872	411469.EUBHAL_01973	0.0	923.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,25VN2@186806|Eubacteriaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NIGDIANH_00873	411469.EUBHAL_01971	1.57e-234	644.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes,25EPT@186801|Clostridia,25VNC@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase,PMI_typeI
NIGDIANH_00874	411469.EUBHAL_01970	8.65e-81	239.0	COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes,24IA4@186801|Clostridia	186801|Clostridia	S	hmm pf06115	manO	-	-	-	-	-	-	-	-	-	-	-	DUF956
NIGDIANH_00875	411469.EUBHAL_01969	6e-68	213.0	COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,24A0K@186801|Clostridia,25WYQ@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor,EIID-AGA
NIGDIANH_00876	411469.EUBHAL_02029	5.88e-51	165.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,25WKC@186806|Eubacteriaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
NIGDIANH_00877	411469.EUBHAL_02028	0.0	1239.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
NIGDIANH_00878	411469.EUBHAL_02027	0.0	1196.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,25VMH@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	hydC	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
NIGDIANH_00879	411469.EUBHAL_02026	1.13e-175	493.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,25V2V@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00880	411469.EUBHAL_02025	3.07e-148	418.0	COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,24GK6@186801|Clostridia,25W2G@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	ppaX	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NIGDIANH_00881	411469.EUBHAL_02024	0.0	865.0	COG0176@1|root,COG0176@2|Bacteria,1UYMX@1239|Firmicutes,249D1@186801|Clostridia,25V8E@186806|Eubacteriaceae	186801|Clostridia	G	Pfam:Transaldolase	-	-	-	-	-	-	-	-	-	-	-	-	TAL_FSA
NIGDIANH_00882	411469.EUBHAL_00541	2.53e-99	288.0	296XG@1|root,2ZU65@2|Bacteria,1V0MN@1239|Firmicutes,24GI1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
NIGDIANH_00883	411469.EUBHAL_00540	5.05e-104	301.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,25CWU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00884	411469.EUBHAL_00539	2.53e-164	458.0	COG4845@1|root,COG4845@2|Bacteria,1UY81@1239|Firmicutes,24853@186801|Clostridia,25WWG@186806|Eubacteriaceae	186801|Clostridia	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
NIGDIANH_00885	411469.EUBHAL_00536	0.0	941.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
NIGDIANH_00887	411469.EUBHAL_01779	6.62e-68	222.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,25VED@186806|Eubacteriaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
NIGDIANH_00889	411469.EUBHAL_01781	0.0	1509.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,25UU8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NIGDIANH_00890	411469.EUBHAL_01782	0.0	1157.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VT3@186806|Eubacteriaceae	186801|Clostridia	H	Thiamine pyrophosphate enzyme, central domain	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NIGDIANH_00891	411469.EUBHAL_01783	1.64e-115	331.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,25W3D@186806|Eubacteriaceae	186801|Clostridia	E	ACT domain	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NIGDIANH_00892	411469.EUBHAL_01968	7.3e-155	438.0	COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,25M5N@186801|Clostridia,25XYY@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
NIGDIANH_00893	411469.EUBHAL_01967	2.49e-229	632.0	COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,24GRK@186801|Clostridia,25XKT@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.191	ko:K02745,ko:K02793,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	M00276,M00277	R02630,R08366	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1,4.A.6.1.4	-	-	PTSIIB_sorb
NIGDIANH_00894	411469.EUBHAL_01966	0.0	1229.0	COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia	186801|Clostridia	GKT	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02538	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
NIGDIANH_00895	411469.EUBHAL_01965	4.69e-219	617.0	COG1299@1|root,COG1299@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,25VG4@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	2.7.1.191	ko:K02793,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NIGDIANH_00896	411469.EUBHAL_01963	2.36e-102	296.0	COG1762@1|root,COG1762@2|Bacteria,1UVGM@1239|Firmicutes,25NTI@186801|Clostridia,25Z34@186806|Eubacteriaceae	186801|Clostridia	H	PTS system, fructose-specific IIA component K02768	-	-	-	-	-	-	-	-	-	-	-	-	PTS_EIIA_2
NIGDIANH_00897	411469.EUBHAL_01960	9.17e-54	168.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NIGDIANH_00898	411469.EUBHAL_01959	5.8e-71	219.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25VX8@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NIGDIANH_00899	411469.EUBHAL_01202	4.65e-187	520.0	COG1512@1|root,COG1512@2|Bacteria,1VB4Q@1239|Firmicutes,24PER@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
NIGDIANH_00900	411469.EUBHAL_01203	3.89e-241	662.0	COG1198@1|root,COG1198@2|Bacteria,1UI22@1239|Firmicutes,25EJI@186801|Clostridia,25ZK0@186806|Eubacteriaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00901	411469.EUBHAL_01461	3.01e-273	749.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,25VQM@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NIGDIANH_00902	411469.EUBHAL_01462	1.28e-273	749.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,25UXS@186806|Eubacteriaceae	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
NIGDIANH_00903	411469.EUBHAL_01464	1.62e-84	248.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,25WYC@186806|Eubacteriaceae	186801|Clostridia	P	Transcriptional regulator, Spx MgsR family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
NIGDIANH_00904	411469.EUBHAL_01465	2.72e-169	471.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,25VRH@186806|Eubacteriaceae	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NIGDIANH_00905	411469.EUBHAL_01466	4.02e-288	788.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,25VW1@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NIGDIANH_00906	1280664.AUIX01000048_gene2868	8.44e-36	145.0	COG0582@1|root,COG0582@2|Bacteria,1TTQ7@1239|Firmicutes,24AD3@186801|Clostridia,4C0EW@830|Butyrivibrio	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NIGDIANH_00908	397290.C810_01709	1.46e-123	361.0	COG4227@1|root,COG4227@2|Bacteria,1UY3K@1239|Firmicutes,24HPV@186801|Clostridia,27Q00@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738
NIGDIANH_00914	397291.C804_03852	5.87e-107	314.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia,27MDN@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NIGDIANH_00916	411469.EUBHAL_02816	2.7e-296	808.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,25V43@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NIGDIANH_00917	411469.EUBHAL_02817	2.03e-117	336.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,25WXD@186806|Eubacteriaceae	186801|Clostridia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NIGDIANH_00918	411469.EUBHAL_02818	1.21e-212	587.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,25VPY@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NIGDIANH_00919	411469.EUBHAL_02819	3.02e-176	491.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,25VBP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NIGDIANH_00920	411469.EUBHAL_00084	2.48e-85	269.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae	186801|Clostridia	C	Carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NIGDIANH_00921	411469.EUBHAL_00085	0.0	870.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,25E8M@186801|Clostridia,25ZQA@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer4,Rubrerythrin
NIGDIANH_00922	411469.EUBHAL_00087	0.0	1749.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae	186801|Clostridia	H	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NIGDIANH_00923	411469.EUBHAL_00088	5.84e-220	607.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae	186801|Clostridia	C	glycyl-radical enzyme activating protein family	pflC	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NIGDIANH_00924	411469.EUBHAL_00089	4.21e-285	779.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	-	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NIGDIANH_00925	411469.EUBHAL_00090	1.78e-82	243.0	COG0662@1|root,COG0662@2|Bacteria,1UI0P@1239|Firmicutes,24SCP@186801|Clostridia,25XPF@186806|Eubacteriaceae	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NIGDIANH_00926	411469.EUBHAL_01903	1.29e-108	323.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,25UWK@186806|Eubacteriaceae	186801|Clostridia	P	Aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
NIGDIANH_00927	411469.EUBHAL_01904	9.13e-163	456.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,25WDH@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NIGDIANH_00928	411469.EUBHAL_01905	6.9e-242	665.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,25VAP@186806|Eubacteriaceae	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NIGDIANH_00929	411469.EUBHAL_01906	2.65e-188	525.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,25WBY@186806|Eubacteriaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NIGDIANH_00930	411469.EUBHAL_01907	2.52e-114	328.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,25W90@186806|Eubacteriaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NIGDIANH_00931	411469.EUBHAL_01908	0.0	1879.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,25VGU@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NIGDIANH_00932	411469.EUBHAL_01909	4.93e-164	460.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia,25WSB@186806|Eubacteriaceae	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
NIGDIANH_00933	411469.EUBHAL_02488	3.09e-291	795.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,25V08@186806|Eubacteriaceae	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NIGDIANH_00934	411469.EUBHAL_02489	1.29e-233	643.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,25V61@186806|Eubacteriaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NIGDIANH_00935	411469.EUBHAL_02490	1.63e-240	667.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,25VMK@186806|Eubacteriaceae	186801|Clostridia	L	Replication initiation and membrane attachment	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
NIGDIANH_00936	411469.EUBHAL_02493	0.0	890.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,25UQR@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NIGDIANH_00937	411469.EUBHAL_02494	2.73e-283	776.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,25UUP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NIGDIANH_00938	411469.EUBHAL_02401	3.81e-253	695.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,25VIF@186806|Eubacteriaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NIGDIANH_00939	411469.EUBHAL_02399	3.03e-256	702.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NIGDIANH_00940	411469.EUBHAL_02398	1.04e-110	318.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,25W6D@186806|Eubacteriaceae	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NIGDIANH_00941	411469.EUBHAL_02397	1.13e-272	745.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,25UV9@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NIGDIANH_00942	411469.EUBHAL_02396	3.09e-174	488.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,25VEB@186806|Eubacteriaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	potC	-	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
NIGDIANH_00943	411469.EUBHAL_02395	9.79e-191	530.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,25VTT@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NIGDIANH_00944	411469.EUBHAL_02394	5.23e-257	704.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25V7Z@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.30,3.6.3.31	ko:K02010,ko:K11072	ko02010,map02010	M00190,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11.1	-	-	ABC_tran,TOBE_2
NIGDIANH_00945	411469.EUBHAL_02393	5.65e-119	340.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25WE3@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
NIGDIANH_00946	411469.EUBHAL_02792	2.85e-249	687.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,25WI5@186806|Eubacteriaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
NIGDIANH_00947	411469.EUBHAL_02793	6.33e-133	376.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,25UWQ@186806|Eubacteriaceae	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NIGDIANH_00948	411469.EUBHAL_02794	9.56e-121	345.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,25WAD@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NIGDIANH_00949	411469.EUBHAL_02795	4.86e-142	401.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,25WCT@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NIGDIANH_00950	411469.EUBHAL_02796	6.79e-74	232.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25V88@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NIGDIANH_00951	411469.EUBHAL_02796	3.64e-176	496.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,25V88@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NIGDIANH_00952	411469.EUBHAL_02797	6.39e-150	422.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,25VZD@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
NIGDIANH_00954	411474.COPEUT_02945	3.95e-08	55.5	2ERJI@1|root,33J51@2|Bacteria,1VMP2@1239|Firmicutes	1239|Firmicutes	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NIGDIANH_00955	411469.EUBHAL_02800	0.0	1001.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,25V02@186806|Eubacteriaceae	186801|Clostridia	J	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NIGDIANH_00956	411469.EUBHAL_02065	0.0	941.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,25VSC@186806|Eubacteriaceae	186801|Clostridia	KT	Serine phosphatase RsbU, regulator of sigma subunit	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NIGDIANH_00957	411469.EUBHAL_02064	0.0	1007.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,25VVD@186806|Eubacteriaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NIGDIANH_00958	411469.EUBHAL_02063	3.15e-135	383.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,25WMX@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NIGDIANH_00959	411469.EUBHAL_02062	0.0	1180.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,25UZC@186806|Eubacteriaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NIGDIANH_00960	411469.EUBHAL_02060	4.07e-215	594.0	2EG7Q@1|root,339ZJ@2|Bacteria,1VJ82@1239|Firmicutes,24SZS@186801|Clostridia,25WVV@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NIGDIANH_00962	411469.EUBHAL_03105	7.07e-222	612.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,25V5X@186806|Eubacteriaceae	186801|Clostridia	K	sugar-binding domain protein	sorC1	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_Crp_2,Sigma70_r4,Sugar-bind
NIGDIANH_00963	411469.EUBHAL_03104	2.16e-289	790.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia,25VAJ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2,Hydrolase_6,Hydrolase_like
NIGDIANH_00964	411469.EUBHAL_02938	9.14e-197	544.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25USK@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.41	ko:K01101,ko:K02566	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
NIGDIANH_00965	411469.EUBHAL_02937	5.17e-99	287.0	COG0698@1|root,COG0698@2|Bacteria,1V2VV@1239|Firmicutes,24GCM@186801|Clostridia,25W2Y@186806|Eubacteriaceae	186801|Clostridia	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NIGDIANH_00966	411469.EUBHAL_02936	0.0	1068.0	COG1069@1|root,COG1069@2|Bacteria,1UHVR@1239|Firmicutes,25E4P@186801|Clostridia,25V3I@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NIGDIANH_00967	411469.EUBHAL_02935	5.47e-103	298.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,25WQ2@186806|Eubacteriaceae	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NIGDIANH_00968	411469.EUBHAL_02934	6.28e-94	274.0	2DQ52@1|root,334SU@2|Bacteria,1VFI1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NIGDIANH_00969	411469.EUBHAL_00132	1.98e-302	825.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
NIGDIANH_00970	411469.EUBHAL_00131	2.35e-98	289.0	COG0664@1|root,COG0664@2|Bacteria,1UXDW@1239|Firmicutes	1239|Firmicutes	K	crp fnr family	rcfB	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
NIGDIANH_00971	1120746.CCNL01000016_gene2337	1.1e-06	52.0	COG2723@1|root,COG2723@2|Bacteria,2NPRZ@2323|unclassified Bacteria	2|Bacteria	G	Glycosyl hydrolase family 1	bglA	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
NIGDIANH_00972	411469.EUBHAL_00129	0.0	1249.0	COG1744@1|root,COG1744@2|Bacteria,1VJR1@1239|Firmicutes,25C7B@186801|Clostridia,25UT5@186806|Eubacteriaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
NIGDIANH_00973	411469.EUBHAL_00128	1.79e-160	447.0	COG2129@1|root,COG2129@2|Bacteria,1V0W0@1239|Firmicutes,24A73@186801|Clostridia,25W5S@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
NIGDIANH_00974	411469.EUBHAL_00127	1.13e-40	134.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	yliE	GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111	-	-	-	-	-	-	-	-	-	-	CHASE9,EAL,GGDEF,PAS_3,PAS_9
NIGDIANH_00975	411469.EUBHAL_00126	8.03e-229	630.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,25UQH@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NIGDIANH_00976	411469.EUBHAL_00125	3.48e-132	379.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,25WP4@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NIGDIANH_00977	411469.EUBHAL_00844	6.71e-102	295.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,25WC9@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NIGDIANH_00978	411469.EUBHAL_00843	9.75e-144	408.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,25VGF@186806|Eubacteriaceae	186801|Clostridia	S	neutral zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NIGDIANH_00979	411469.EUBHAL_00842	8.17e-124	352.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,25WPF@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NIGDIANH_00980	411469.EUBHAL_00841	1.27e-248	683.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25VZZ@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NIGDIANH_00981	411469.EUBHAL_00840	1.83e-123	361.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_00982	411469.EUBHAL_00840	1.85e-116	342.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_00983	411469.EUBHAL_00839	0.0	1343.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25ZN2@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg,SBP_bac_3
NIGDIANH_00984	411469.EUBHAL_00839	9.09e-36	135.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,25ZN2@186806|Eubacteriaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg,SBP_bac_3
NIGDIANH_00985	411469.EUBHAL_02724	0.0	1354.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,25V6M@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NIGDIANH_00986	411469.EUBHAL_02725	2.38e-127	362.0	COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,24MVX@186801|Clostridia,25X2U@186806|Eubacteriaceae	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
NIGDIANH_00987	411469.EUBHAL_02727	6.75e-96	280.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,25X4F@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NIGDIANH_00988	411469.EUBHAL_02728	4.05e-285	779.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NIGDIANH_00989	411469.EUBHAL_02729	1.4e-281	770.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,25V9Z@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NIGDIANH_00990	411469.EUBHAL_01290	5.47e-76	228.0	COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,25WYV@186806|Eubacteriaceae	186801|Clostridia	H	PTS system fructose IIA component	-	-	2.7.1.121	ko:K05881	ko00561,map00561	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000,ko02000	-	-	-	EIIA-man
NIGDIANH_00991	411469.EUBHAL_01289	2.37e-134	383.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,25VQY@186806|Eubacteriaceae	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	dhaL	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
NIGDIANH_00992	411469.EUBHAL_01288	8.62e-233	641.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,25VWW@186806|Eubacteriaceae	186801|Clostridia	H	Dihydroxyacetone kinase, DhaK subunit	dhaK	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
NIGDIANH_00993	411469.EUBHAL_01287	9.42e-28	100.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,25XHW@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NIGDIANH_00994	411469.EUBHAL_01286	2.58e-226	624.0	COG1619@1|root,COG1619@2|Bacteria,1TRBB@1239|Firmicutes,24ABA@186801|Clostridia,25W50@186806|Eubacteriaceae	186801|Clostridia	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
NIGDIANH_00995	411469.EUBHAL_01284	1.68e-177	494.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,25UY6@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NIGDIANH_00996	411469.EUBHAL_01283	3.2e-143	404.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,25V5D@186806|Eubacteriaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NIGDIANH_00997	411469.EUBHAL_01282	2.87e-43	140.0	2EIFH@1|root,33C6V@2|Bacteria,1VNPG@1239|Firmicutes,24V5E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_00998	411469.EUBHAL_01232	0.0	1025.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NIGDIANH_00999	411469.EUBHAL_02039	6.13e-128	363.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
NIGDIANH_01000	411469.EUBHAL_02040	2.24e-238	654.0	COG2755@1|root,COG2755@2|Bacteria,1V254@1239|Firmicutes,24J71@186801|Clostridia	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01001	411469.EUBHAL_02041	0.0	1005.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,25V5N@186806|Eubacteriaceae	186801|Clostridia	M	membrane protein involved in D-alanine export	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
NIGDIANH_01002	411469.EUBHAL_02042	2.25e-45	146.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia,25X76@186806|Eubacteriaceae	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NIGDIANH_01003	411469.EUBHAL_02043	0.0	1038.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,25V6D@186806|Eubacteriaceae	186801|Clostridia	Q	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
NIGDIANH_01004	411469.EUBHAL_00923	1.04e-231	645.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,25VG1@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
NIGDIANH_01007	411469.EUBHAL_00927	3.6e-272	745.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,25UZN@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NIGDIANH_01009	411469.EUBHAL_00932	1.86e-213	590.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,25X4Z@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NIGDIANH_01010	411469.EUBHAL_02274	4.71e-74	222.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,25WN4@186806|Eubacteriaceae	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NIGDIANH_01011	411469.EUBHAL_02273	1.57e-180	502.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,25V0M@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NIGDIANH_01012	411469.EUBHAL_02272	5.75e-119	340.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,25X91@186806|Eubacteriaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
NIGDIANH_01013	411469.EUBHAL_02271	6.22e-43	140.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,25X88@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NIGDIANH_01014	411469.EUBHAL_02270	5.2e-52	164.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,25X5P@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NIGDIANH_01015	411469.EUBHAL_02269	7.42e-311	848.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,25V24@186806|Eubacteriaceae	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NIGDIANH_01016	411469.EUBHAL_02268	1.56e-78	233.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,25X21@186806|Eubacteriaceae	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NIGDIANH_01017	411469.EUBHAL_02267	6.88e-130	368.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,25W6N@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NIGDIANH_01019	1235790.C805_01371	1.01e-05	46.2	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia,25XYD@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01020	411469.EUBHAL_02264	1.61e-310	847.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,25V48@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NIGDIANH_01021	411469.EUBHAL_02263	6.21e-147	413.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,25WVH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NIGDIANH_01022	411469.EUBHAL_01068	4.95e-225	622.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,25VF4@186806|Eubacteriaceae	186801|Clostridia	S	Bile acid transporter	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
NIGDIANH_01023	411469.EUBHAL_01069	2.35e-56	175.0	2DQ38@1|root,334JJ@2|Bacteria,1VJ5Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01024	411469.EUBHAL_00648	1.67e-199	555.0	COG0679@1|root,COG0679@2|Bacteria,1V28G@1239|Firmicutes,24H5F@186801|Clostridia	186801|Clostridia	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NIGDIANH_01025	411469.EUBHAL_00649	1.81e-157	442.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,25VX8@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NIGDIANH_01026	411469.EUBHAL_00650	3.11e-217	597.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,24B9K@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NIGDIANH_01027	411469.EUBHAL_00651	1.86e-211	582.0	COG0726@1|root,COG0726@2|Bacteria,1VA2Q@1239|Firmicutes,24FN0@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NIGDIANH_01028	411469.EUBHAL_00652	0.0	937.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,25VM4@186806|Eubacteriaceae	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NIGDIANH_01029	411469.EUBHAL_01308	1.12e-51	171.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,25VIX@186806|Eubacteriaceae	186801|Clostridia	J	DHHA1 domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NIGDIANH_01030	411469.EUBHAL_01309	5.67e-243	668.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,25VJZ@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
NIGDIANH_01031	411469.EUBHAL_01310	6.3e-222	612.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,25VWI@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NIGDIANH_01032	411469.EUBHAL_01311	3.59e-147	414.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,25W68@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
NIGDIANH_01033	411469.EUBHAL_01312	5.25e-175	487.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,25WIS@186806|Eubacteriaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NIGDIANH_01034	411469.EUBHAL_01313	2.6e-184	512.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_01035	411469.EUBHAL_03222	1.72e-58	181.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,25XAB@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
NIGDIANH_01036	411469.EUBHAL_03223	7.12e-227	625.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,25V8W@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NIGDIANH_01037	411469.EUBHAL_03224	0.0	875.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_01038	411469.EUBHAL_03226	7.46e-85	249.0	2E8UY@1|root,3335C@2|Bacteria,1VI3A@1239|Firmicutes,24RP2@186801|Clostridia	186801|Clostridia	S	TerY-C metal binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TerY_C
NIGDIANH_01039	411469.EUBHAL_03227	4.62e-192	533.0	COG0631@1|root,COG0631@2|Bacteria,1V75W@1239|Firmicutes,24KMZ@186801|Clostridia	186801|Clostridia	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
NIGDIANH_01040	411469.EUBHAL_03228	5.89e-186	517.0	COG4245@1|root,COG4245@2|Bacteria,1V3ER@1239|Firmicutes,24GIK@186801|Clostridia	186801|Clostridia	S	Von Willebrand factor	-	-	-	-	-	-	-	-	-	-	-	-	VWA
NIGDIANH_01041	411469.EUBHAL_03229	9.36e-298	811.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01042	411469.EUBHAL_03230	1.02e-187	528.0	COG4248@1|root,COG4248@2|Bacteria,1UZ2E@1239|Firmicutes,24E7G@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NIGDIANH_01043	411469.EUBHAL_02160	0.0	1325.0	2DGTK@1|root,2ZX8T@2|Bacteria,1V4M1@1239|Firmicutes,24HP5@186801|Clostridia,25ZQH@186806|Eubacteriaceae	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01044	411469.EUBHAL_02159	1.48e-226	624.0	COG0463@1|root,COG0463@2|Bacteria,1UI8D@1239|Firmicutes,247P4@186801|Clostridia,25V3J@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_01045	411469.EUBHAL_02157	7.21e-236	648.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,25V7X@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NIGDIANH_01046	411469.EUBHAL_02156	1.57e-219	612.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,25VUJ@186806|Eubacteriaceae	186801|Clostridia	S	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NIGDIANH_01047	411469.EUBHAL_02154	2.13e-40	133.0	2EHCX@1|root,31TEV@2|Bacteria,1TUTI@1239|Firmicutes,258C7@186801|Clostridia,25XS1@186806|Eubacteriaceae	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
NIGDIANH_01048	411469.EUBHAL_02153	8.37e-57	178.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,25XSD@186806|Eubacteriaceae	186801|Clostridia	S	CotJB protein	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
NIGDIANH_01049	411469.EUBHAL_02152	1.69e-45	146.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,25X7P@186806|Eubacteriaceae	186801|Clostridia	P	Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NIGDIANH_01050	411469.EUBHAL_01736	8.14e-63	192.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,25WX7@186806|Eubacteriaceae	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
NIGDIANH_01051	411469.EUBHAL_01735	1.26e-127	364.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,25VEH@186806|Eubacteriaceae	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NIGDIANH_01052	411469.EUBHAL_01734	8.75e-145	408.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,25VIA@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NIGDIANH_01053	411469.EUBHAL_01733	2.75e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,25WIW@186806|Eubacteriaceae	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NIGDIANH_01054	411469.EUBHAL_01732	1.34e-260	720.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,25WF5@186806|Eubacteriaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NIGDIANH_01055	411469.EUBHAL_01731	1.9e-108	312.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NIGDIANH_01057	411469.EUBHAL_01729	4.59e-150	421.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,25WG0@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NIGDIANH_01058	411469.EUBHAL_01888	0.0	890.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,25UVU@186806|Eubacteriaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NIGDIANH_01059	411469.EUBHAL_01887	2.12e-88	261.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,25X56@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01060	411469.EUBHAL_01886	0.0	1253.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
NIGDIANH_01061	411469.EUBHAL_01884	5.13e-83	246.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,25WXV@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NIGDIANH_01062	411469.EUBHAL_02717	9.54e-113	324.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,25VBH@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NIGDIANH_01063	411469.EUBHAL_02716	2.1e-124	355.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,25W8B@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NIGDIANH_01064	411469.EUBHAL_02715	1.41e-168	480.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,25UQB@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NIGDIANH_01065	742740.HMPREF9474_02676	3.18e-144	437.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,24819@186801|Clostridia,21ZS7@1506553|Lachnoclostridium	186801|Clostridia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB2	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
NIGDIANH_01066	742741.HMPREF9475_02015	1.09e-96	290.0	29ZAH@1|root,30M8W@2|Bacteria,1V4K9@1239|Firmicutes,24FB4@186801|Clostridia,21ZE3@1506553|Lachnoclostridium	186801|Clostridia	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
NIGDIANH_01067	411459.RUMOBE_00751	7.13e-107	311.0	COG4123@1|root,COG4123@2|Bacteria,1UK35@1239|Firmicutes,25FHR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
NIGDIANH_01068	742740.HMPREF9474_03913	1.69e-221	617.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,220XW@1506553|Lachnoclostridium	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NIGDIANH_01069	742740.HMPREF9474_03914	4.24e-189	533.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,25CBV@186801|Clostridia	186801|Clostridia	M	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS
NIGDIANH_01070	411469.EUBHAL_02019	1.08e-244	672.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,25WGG@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NIGDIANH_01071	411469.EUBHAL_02020	6.61e-192	533.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,25UYF@186806|Eubacteriaceae	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NIGDIANH_01072	411469.EUBHAL_02021	7.77e-197	546.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,25UYX@186806|Eubacteriaceae	186801|Clostridia	P	permease	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NIGDIANH_01073	411469.EUBHAL_02022	0.0	894.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
NIGDIANH_01074	411469.EUBHAL_00762	2.77e-270	740.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	mtlD	-	1.1.1.17	ko:K00009	ko00051,map00051	-	R02703	RC00085	ko00000,ko00001,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NIGDIANH_01075	411469.EUBHAL_00761	0.0	1165.0	COG2213@1|root,COG4668@1|root,COG2213@2|Bacteria,COG4668@2|Bacteria,1TPE3@1239|Firmicutes,24A04@186801|Clostridia,25UWX@186806|Eubacteriaceae	186801|Clostridia	G	PTS system, Lactose/Cellobiose specific IIB subunit	mtlA	-	2.7.1.197	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	M00274	R02704	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1.12,4.A.2.1.2,4.A.2.1.24,4.A.2.1.5	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NIGDIANH_01076	411469.EUBHAL_00759	0.0	1377.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,248PT@186801|Clostridia,25WY5@186806|Eubacteriaceae	186801|Clostridia	GKT	Psort location Cytoplasmic, score	-	-	-	ko:K03483	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB
NIGDIANH_01077	411469.EUBHAL_00763	0.0	939.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NIGDIANH_01078	411469.EUBHAL_00764	6.81e-174	486.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NIGDIANH_01079	411469.EUBHAL_00765	8.76e-238	655.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25VYA@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K19081	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c
NIGDIANH_01080	411469.EUBHAL_00766	4.31e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01081	411469.EUBHAL_00767	4.95e-216	596.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,25X2I@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01082	411469.EUBHAL_00768	3.21e-243	668.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,25VSG@186806|Eubacteriaceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NIGDIANH_01083	411469.EUBHAL_02384	3.66e-96	290.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,25VQI@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NIGDIANH_01084	411469.EUBHAL_02385	1.68e-180	503.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,25WR4@186806|Eubacteriaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
NIGDIANH_01085	411469.EUBHAL_02386	1.65e-263	723.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,25UZZ@186806|Eubacteriaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NIGDIANH_01087	411469.EUBHAL_02388	1.48e-164	461.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,25UXX@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NIGDIANH_01088	411469.EUBHAL_02389	2.46e-178	498.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,25VP9@186806|Eubacteriaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NIGDIANH_01089	411469.EUBHAL_02391	1.44e-184	513.0	COG1058@1|root,COG1058@2|Bacteria,1UHPB@1239|Firmicutes,25FNU@186801|Clostridia	186801|Clostridia	S	Probable molybdopterin binding domain	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NIGDIANH_01090	411469.EUBHAL_02915	2.25e-99	293.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia,25WGR@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
NIGDIANH_01091	411902.CLOBOL_00012	1.45e-10	62.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24VHG@186801|Clostridia,2241W@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01092	411469.EUBHAL_02917	3.13e-226	623.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NIGDIANH_01093	411469.EUBHAL_02918	0.0	1043.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,25VWZ@186806|Eubacteriaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NIGDIANH_01094	411469.EUBHAL_02919	0.0	927.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,25V57@186806|Eubacteriaceae	186801|Clostridia	G	Pyruvate kinase	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NIGDIANH_01095	411469.EUBHAL_02920	7.3e-305	832.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,25VIR@186806|Eubacteriaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NIGDIANH_01097	411469.EUBHAL_01292	1.48e-279	766.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,25W4V@186806|Eubacteriaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NIGDIANH_01098	411469.EUBHAL_01293	5.08e-237	652.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,25V1W@186806|Eubacteriaceae	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NIGDIANH_01099	411469.EUBHAL_01294	3.33e-118	338.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,25WKQ@186806|Eubacteriaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NIGDIANH_01100	411469.EUBHAL_01295	0.0	1030.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,25VNR@186806|Eubacteriaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NIGDIANH_01101	411469.EUBHAL_01296	0.0	1112.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,25UTR@186806|Eubacteriaceae	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NIGDIANH_01102	411469.EUBHAL_01297	3.8e-43	140.0	COG4224@1|root,COG4224@2|Bacteria,1UQR0@1239|Firmicutes,258HB@186801|Clostridia,25XM2@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF896)	-	-	-	-	-	-	-	-	-	-	-	-	DUF896
NIGDIANH_01103	411469.EUBHAL_01717	2.65e-216	597.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,25VY5@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01104	411469.EUBHAL_01718	9.72e-156	437.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NIGDIANH_01105	411469.EUBHAL_01719	5.78e-30	107.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25X8S@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NIGDIANH_01106	411469.EUBHAL_01720	4.7e-50	162.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NIGDIANH_01107	411469.EUBHAL_01720	1.13e-07	52.8	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NIGDIANH_01108	411469.EUBHAL_01721	4.18e-118	338.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,25XIU@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NIGDIANH_01109	411469.EUBHAL_01722	0.0	961.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,25V5E@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NIGDIANH_01110	411469.EUBHAL_01723	2.23e-204	566.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,25VH1@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NIGDIANH_01111	411469.EUBHAL_01902	4.87e-74	229.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25UWA@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NIGDIANH_01112	411469.EUBHAL_01902	2.14e-117	342.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,25UWA@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NIGDIANH_01113	411469.EUBHAL_01901	6.65e-202	578.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25VTD@186806|Eubacteriaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NIGDIANH_01114	411469.EUBHAL_01901	1.41e-255	717.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,25VTD@186806|Eubacteriaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NIGDIANH_01115	411469.EUBHAL_01900	0.0	1705.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,25V4T@186806|Eubacteriaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NIGDIANH_01116	411469.EUBHAL_02700	2.23e-105	320.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,25VK9@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NIGDIANH_01117	411469.EUBHAL_02700	3.85e-60	200.0	COG1961@1|root,COG1961@2|Bacteria,1TRVQ@1239|Firmicutes,249AZ@186801|Clostridia,25VK9@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NIGDIANH_01118	411469.EUBHAL_02701	2.97e-142	401.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25VVN@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NIGDIANH_01119	411469.EUBHAL_02702	3.32e-265	725.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,25V65@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NIGDIANH_01120	411469.EUBHAL_02703	0.0	2113.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,25UTY@186806|Eubacteriaceae	186801|Clostridia	F	carbamoylphosphate synthase large subunit	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NIGDIANH_01121	411469.EUBHAL_02992	0.0	1294.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia,25XJQ@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	Sulfatase
NIGDIANH_01122	411469.EUBHAL_02991	3.12e-151	434.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,25VEF@186806|Eubacteriaceae	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NIGDIANH_01123	411469.EUBHAL_02990	4.29e-89	262.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,25XIA@186806|Eubacteriaceae	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NIGDIANH_01124	411469.EUBHAL_02989	0.0	1274.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,25V92@186806|Eubacteriaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
NIGDIANH_01125	411469.EUBHAL_02988	1.83e-49	157.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,25XJX@186806|Eubacteriaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NIGDIANH_01126	411469.EUBHAL_01943	5.31e-142	409.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,25V1T@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NIGDIANH_01127	411469.EUBHAL_01944	5.81e-155	436.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,25W54@186806|Eubacteriaceae	186801|Clostridia	E	AzlC protein	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
NIGDIANH_01128	411469.EUBHAL_01945	3.34e-58	181.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,25ZWZ@186806|Eubacteriaceae	186801|Clostridia	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
NIGDIANH_01129	411469.EUBHAL_01947	0.0	2934.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
NIGDIANH_01130	411469.EUBHAL_01376	1.21e-93	274.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,25WRI@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NIGDIANH_01131	1410632.JHWW01000001_gene1355	3.15e-34	117.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,27PS5@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NIGDIANH_01132	411469.EUBHAL_01379	5.23e-77	229.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,25WQ4@186806|Eubacteriaceae	186801|Clostridia	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
NIGDIANH_01133	411469.EUBHAL_01380	0.0	1075.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,25VT6@186806|Eubacteriaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
NIGDIANH_01134	411469.EUBHAL_01381	0.0	1338.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,25VDR@186806|Eubacteriaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NIGDIANH_01135	411469.EUBHAL_01382	8.72e-174	484.0	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,24GVA@186801|Clostridia,25XEM@186806|Eubacteriaceae	186801|Clostridia	T	Tyrosine phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	Y_phosphatase3
NIGDIANH_01136	411469.EUBHAL_02195	2.07e-154	437.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,25WQJ@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NIGDIANH_01138	411469.EUBHAL_02197	2.75e-216	597.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,25V49@186806|Eubacteriaceae	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NIGDIANH_01139	411469.EUBHAL_02198	1.03e-202	561.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,25VW9@186806|Eubacteriaceae	186801|Clostridia	S	esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
NIGDIANH_01140	411469.EUBHAL_02200	0.0	890.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,25V00@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NIGDIANH_01141	411469.EUBHAL_02201	6.9e-298	812.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,25V8H@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NIGDIANH_01142	411469.EUBHAL_03262	3.86e-302	823.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
NIGDIANH_01143	411469.EUBHAL_03261	9.22e-309	840.0	COG4857@1|root,COG4857@2|Bacteria,1TPHY@1239|Firmicutes,249RB@186801|Clostridia,25VMG@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	mtnK	-	2.7.1.100	ko:K00899	ko00270,ko01100,map00270,map01100	M00034	R04143	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
NIGDIANH_01144	411469.EUBHAL_03260	1.33e-112	323.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24SP8@186801|Clostridia,25YNZ@186806|Eubacteriaceae	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NIGDIANH_01145	411469.EUBHAL_03259	1.64e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1VB54@1239|Firmicutes,24JK9@186801|Clostridia,25WUX@186806|Eubacteriaceae	186801|Clostridia	E	BMC	pduU	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NIGDIANH_01146	411469.EUBHAL_03258	3.68e-241	666.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,25WP6@186806|Eubacteriaceae	186801|Clostridia	D	Stage II sporulation protein	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NIGDIANH_01147	411469.EUBHAL_03257	3.85e-44	154.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,25WHT@186806|Eubacteriaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NIGDIANH_01148	1232453.BAIF02000102_gene3650	4.54e-179	509.0	COG2304@1|root,COG2304@2|Bacteria,1VSJ8@1239|Firmicutes	1239|Firmicutes	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01149	471875.RUMLAC_00871	0.0	1634.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NIGDIANH_01150	471875.RUMLAC_00869	4.5e-103	300.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3WIIU@541000|Ruminococcaceae	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NIGDIANH_01151	411469.EUBHAL_03086	0.0	1724.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,25V1V@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NIGDIANH_01152	411469.EUBHAL_03085	1.69e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,25WU6@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NIGDIANH_01153	411469.EUBHAL_03084	4.14e-235	647.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,25WBE@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
NIGDIANH_01154	411469.EUBHAL_03083	1.12e-162	461.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,25UVY@186806|Eubacteriaceae	186801|Clostridia	H	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
NIGDIANH_01155	411469.EUBHAL_03083	3.23e-79	244.0	COG0469@1|root,COG0469@2|Bacteria,1TQC0@1239|Firmicutes,24CHE@186801|Clostridia,25UVY@186806|Eubacteriaceae	186801|Clostridia	H	HpcH/HpaI aldolase/citrate lyase family	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK
NIGDIANH_01156	585394.RHOM_10870	3.48e-33	114.0	COG3177@1|root,COG3177@2|Bacteria,1VISE@1239|Firmicutes,24R8K@186801|Clostridia	186801|Clostridia	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01157	585394.RHOM_10875	0.0	946.0	28HPA@1|root,2Z7XB@2|Bacteria,1TRBX@1239|Firmicutes,24AUG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NIGDIANH_01159	585394.RHOM_10885	6.45e-70	211.0	28ZZK@1|root,2ZMPX@2|Bacteria,1VHF7@1239|Firmicutes,24NQM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01160	585394.RHOM_10890	3.12e-213	589.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NIGDIANH_01161	411469.EUBHAL_01836	1.5e-229	632.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,25UZW@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NIGDIANH_01162	411469.EUBHAL_01835	0.0	1574.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,25VY4@186806|Eubacteriaceae	186801|Clostridia	S	DNA internalization competence protein ComEC Rec2-like protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NIGDIANH_01163	411469.EUBHAL_01834	4.88e-217	601.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,25W13@186806|Eubacteriaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
NIGDIANH_01164	411469.EUBHAL_01833	0.0	882.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,25UZG@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_01165	411469.EUBHAL_01832	1.24e-77	235.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,25VA8@186806|Eubacteriaceae	186801|Clostridia	T	response regulator	yycF	-	-	ko:K07668	ko02020,map02020	M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01166	411469.EUBHAL_02969	0.0	1661.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,25ZU7@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NIGDIANH_01167	411469.EUBHAL_02967	0.0	1684.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25USQ@186806|Eubacteriaceae	186801|Clostridia	C	Pyruvate formate lyase-like	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NIGDIANH_01168	411469.EUBHAL_00274	1.31e-16	76.6	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25Z5N@186806|Eubacteriaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NIGDIANH_01169	411470.RUMGNA_01788	2.84e-158	468.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
NIGDIANH_01171	457412.RSAG_03473	1.57e-286	795.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
NIGDIANH_01172	411469.EUBHAL_01866	1.19e-214	595.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24DHE@186801|Clostridia	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sigma70_r4,Sigma70_r4_2,Sugar-bind
NIGDIANH_01173	411469.EUBHAL_01865	0.0	1339.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,FIST,FIST_C,HATPase_c,HisKA,Response_reg,dCache_1
NIGDIANH_01174	1305737.JAFX01000001_gene313	1.28e-08	58.2	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,4NDXU@976|Bacteroidetes,47JK3@768503|Cytophagia	976|Bacteroidetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,AAA_16,GAF,GAF_2,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Pkinase,Response_reg,SpoIIE,Y_Y_Y
NIGDIANH_01175	411469.EUBHAL_02785	0.0	985.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,25V1N@186806|Eubacteriaceae	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NIGDIANH_01176	411469.EUBHAL_02786	1.43e-52	166.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25X0R@186806|Eubacteriaceae	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NIGDIANH_01178	411469.EUBHAL_02788	1.86e-252	696.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,25VWV@186806|Eubacteriaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M23,Peptidase_M56,Transpeptidase
NIGDIANH_01179	411469.EUBHAL_02789	1.21e-82	244.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NIGDIANH_01180	411469.EUBHAL_02791	6.7e-191	531.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,25UV5@186806|Eubacteriaceae	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NIGDIANH_01181	97139.C824_00038	1.48e-63	219.0	2EAE3@1|root,334HP@2|Bacteria,1VHM2@1239|Firmicutes,24K95@186801|Clostridia,36TDJ@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01182	999413.HMPREF1094_04705	4.25e-172	512.0	28KSN@1|root,2Z9PR@2|Bacteria,1TSZJ@1239|Firmicutes,3VS4J@526524|Erysipelotrichia	526524|Erysipelotrichia	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
NIGDIANH_01183	1235792.C808_00065	1.82e-65	204.0	2F1A0@1|root,33UB0@2|Bacteria,1VUUK@1239|Firmicutes,24Q4U@186801|Clostridia,27RY5@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01184	1121877.JQKF01000001_gene1334	3.74e-06	51.2	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4CN63@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
NIGDIANH_01185	97139.C824_06117	9.79e-83	254.0	2APHD@1|root,31EKC@2|Bacteria,1V7GX@1239|Firmicutes,24GBC@186801|Clostridia,36NFD@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01189	411469.EUBHAL_02954	2.8e-230	634.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,25W78@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
NIGDIANH_01190	411469.EUBHAL_02953	8.51e-137	387.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,25VE4@186806|Eubacteriaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
NIGDIANH_01191	411469.EUBHAL_02952	0.0	1456.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,25VQG@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NIGDIANH_01192	411469.EUBHAL_02951	2.67e-308	840.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,25VCR@186806|Eubacteriaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NIGDIANH_01193	411469.EUBHAL_02950	4.11e-30	110.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,25VNY@186806|Eubacteriaceae	186801|Clostridia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NIGDIANH_01194	622312.ROSEINA2194_02066	2.98e-78	233.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NIGDIANH_01195	622312.ROSEINA2194_02067	5.95e-112	322.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NIGDIANH_01196	622312.ROSEINA2194_02068	3.49e-33	115.0	COG1841@1|root,COG1841@2|Bacteria	2|Bacteria	J	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	rpmD	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NIGDIANH_01197	622312.ROSEINA2194_02069	2.55e-95	278.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NIGDIANH_01198	622312.ROSEINA2194_02070	7.35e-307	838.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NIGDIANH_01199	622312.ROSEINA2194_02071	1.11e-154	434.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NIGDIANH_01200	622312.ROSEINA2194_02072	5.93e-191	529.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NIGDIANH_01201	397290.C810_00319	2.07e-20	84.7	COG2163@1|root,COG2163@2|Bacteria,1VEPA@1239|Firmicutes,24UP0@186801|Clostridia,27QCW@186928|unclassified Lachnospiraceae	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01202	622312.ROSEINA2194_02074	1.4e-44	144.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NIGDIANH_01203	622312.ROSEINA2194_02077	2.13e-83	246.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NIGDIANH_01204	411469.EUBHAL_01525	0.0	1019.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,25VCU@186806|Eubacteriaceae	186801|Clostridia	S	Membrane protein involved in the export of O-antigen and teichoic acid	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NIGDIANH_01205	411469.EUBHAL_01524	0.0	932.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,25V1Q@186806|Eubacteriaceae	186801|Clostridia	F	adenylosuccinate lyase	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NIGDIANH_01206	411469.EUBHAL_01523	0.0	922.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,25VI2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NIGDIANH_01207	411469.EUBHAL_01522	3.59e-78	243.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,25W9X@186806|Eubacteriaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
NIGDIANH_01208	411469.EUBHAL_00672	5.54e-93	289.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,25VG3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NIGDIANH_01209	411469.EUBHAL_00671	3.88e-207	573.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,25UXV@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI,Shikimate_DH,Shikimate_dh_N
NIGDIANH_01210	411469.EUBHAL_00670	3.84e-296	810.0	COG0477@1|root,COG2814@2|Bacteria,1UNUP@1239|Firmicutes,25FJG@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NIGDIANH_01211	411469.EUBHAL_00669	5.14e-111	319.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NIGDIANH_01212	411469.EUBHAL_00668	8.81e-285	781.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,25VRS@186806|Eubacteriaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
NIGDIANH_01213	411469.EUBHAL_00667	1.59e-244	672.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,25XCE@186806|Eubacteriaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
NIGDIANH_01214	411469.EUBHAL_00376	0.0	1062.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,25V32@186806|Eubacteriaceae	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NIGDIANH_01215	411469.EUBHAL_00377	2.84e-162	453.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,25WHB@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NIGDIANH_01216	411469.EUBHAL_00378	0.0	975.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,25V7K@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NIGDIANH_01217	411469.EUBHAL_00379	1.16e-139	394.0	COG3437@1|root,COG3437@2|Bacteria,1UHZZ@1239|Firmicutes,25E8P@186801|Clostridia,25ZUA@186806|Eubacteriaceae	186801|Clostridia	KT	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
NIGDIANH_01218	411469.EUBHAL_00158	2.87e-88	259.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,25XA6@186806|Eubacteriaceae	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NIGDIANH_01219	411469.EUBHAL_00159	2.02e-290	793.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,25V6S@186806|Eubacteriaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NIGDIANH_01220	553973.CLOHYLEM_06735	2.19e-06	48.1	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,221F7@1506553|Lachnoclostridium	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NIGDIANH_01221	411469.EUBHAL_00161	8.4e-203	562.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,25VS6@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NIGDIANH_01222	411469.EUBHAL_00162	0.0	1236.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,25UUI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NIGDIANH_01223	411469.EUBHAL_00163	1.57e-193	537.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,25VEW@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NIGDIANH_01224	411469.EUBHAL_01305	8.74e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,25XF8@186806|Eubacteriaceae	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
NIGDIANH_01225	411469.EUBHAL_01304	2.01e-57	178.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,25X7A@186806|Eubacteriaceae	186801|Clostridia	K	nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
NIGDIANH_01226	411469.EUBHAL_01303	4.53e-268	737.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,25URA@186806|Eubacteriaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NIGDIANH_01227	411469.EUBHAL_01302	1.15e-101	295.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,25WA4@186806|Eubacteriaceae	186801|Clostridia	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
NIGDIANH_01228	411469.EUBHAL_01301	6.21e-273	783.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,25VC5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NIGDIANH_01229	411469.EUBHAL_01300	9.95e-86	271.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NIGDIANH_01230	411469.EUBHAL_00769	1.8e-89	266.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NIGDIANH_01231	411469.EUBHAL_00770	4.25e-49	156.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NIGDIANH_01232	411469.EUBHAL_00771	2.69e-181	504.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,25WB2@186806|Eubacteriaceae	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
NIGDIANH_01233	411469.EUBHAL_00772	3.29e-60	186.0	2EEV1@1|root,338NH@2|Bacteria,1VHUX@1239|Firmicutes,24TNK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NIGDIANH_01234	411469.EUBHAL_00773	9.43e-316	860.0	28K19@1|root,2Z9R2@2|Bacteria,1TT42@1239|Firmicutes,249G4@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	zf-ribbon_3
NIGDIANH_01235	411469.EUBHAL_00774	5.87e-194	539.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,25ZSI@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NIGDIANH_01236	411469.EUBHAL_00775	1.5e-83	247.0	2D04F@1|root,32T7R@2|Bacteria,1VBXI@1239|Firmicutes,24N5C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NIGDIANH_01237	411469.EUBHAL_00790	9.5e-183	514.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25V5M@186806|Eubacteriaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NIGDIANH_01238	1235788.C802_03542	2.46e-60	223.0	COG1409@1|root,COG5635@1|root,COG1409@2|Bacteria,COG5635@2|Bacteria,4P02I@976|Bacteroidetes,2FWIQ@200643|Bacteroidia	976|Bacteroidetes	T	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
NIGDIANH_01239	1226325.HMPREF1548_03500	6.24e-138	395.0	2CJZW@1|root,2ZC29@2|Bacteria,1V2Z2@1239|Firmicutes,24H6F@186801|Clostridia,36S8N@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01243	411469.EUBHAL_01250	0.0	2183.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,25V6H@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase deoxyribonuclease subunit B	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
NIGDIANH_01245	411469.EUBHAL_03236	1.06e-187	521.0	2EAC2@1|root,334G5@2|Bacteria,1UK4Q@1239|Firmicutes,24R61@186801|Clostridia,25ZJJ@186806|Eubacteriaceae	186801|Clostridia	S	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,NLPC_P60
NIGDIANH_01246	411469.EUBHAL_03235	4.39e-226	624.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia,25WSP@186806|Eubacteriaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NIGDIANH_01247	411469.EUBHAL_03234	8.24e-43	139.0	2E7X8@1|root,332BT@2|Bacteria,1VG5Y@1239|Firmicutes,24RJD@186801|Clostridia,25ZBZ@186806|Eubacteriaceae	186801|Clostridia	S	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
NIGDIANH_01249	411469.EUBHAL_03232	0.0	925.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,25V9C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NIGDIANH_01250	411469.EUBHAL_01958	4.79e-309	842.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,25V9P@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
NIGDIANH_01251	411469.EUBHAL_01957	1.17e-271	743.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
NIGDIANH_01252	411469.EUBHAL_01956	1.16e-241	664.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfA	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
NIGDIANH_01253	411469.EUBHAL_01955	1.62e-187	521.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
NIGDIANH_01254	411469.EUBHAL_01954	1.87e-148	428.0	COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia,25VPQ@186806|Eubacteriaceae	186801|Clostridia	C	glycolate oxidase, subunit GlcD	glcD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
NIGDIANH_01255	742740.HMPREF9474_03509	7.87e-58	182.0	2CEQV@1|root,32S0A@2|Bacteria,1VBZ1@1239|Firmicutes,25D42@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01256	585501.HMPREF6123_0830	3.19e-24	97.4	2EAWI@1|root,334XS@2|Bacteria,1VHTN@1239|Firmicutes,24HT9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01257	33035.JPJF01000093_gene2246	1.2e-61	193.0	2CPV6@1|root,32SJY@2|Bacteria,1VCAK@1239|Firmicutes,24HJI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01259	1294142.CINTURNW_1037	1.69e-18	80.5	2EFFA@1|root,33983@2|Bacteria,1VJ6U@1239|Firmicutes,24MSJ@186801|Clostridia,36M60@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Gp15
NIGDIANH_01260	33035.JPJF01000093_gene2243	0.0	909.0	COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,249I0@186801|Clostridia,3Y0ZQ@572511|Blautia	186801|Clostridia	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01261	33035.JPJF01000093_gene2242	7.18e-50	161.0	2DTNS@1|root,33M3M@2|Bacteria,1VM94@1239|Firmicutes,24VR3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01262	411469.EUBHAL_02486	9.74e-178	495.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,25WUH@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NIGDIANH_01263	411469.EUBHAL_02487	0.0	1312.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia,25UUN@186806|Eubacteriaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NIGDIANH_01264	1120998.AUFC01000012_gene468	2.99e-28	103.0	COG3655@1|root,COG3655@2|Bacteria,1VGZ2@1239|Firmicutes,24TD9@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
NIGDIANH_01265	877414.ATWA01000150_gene1	4.88e-86	260.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,26AYY@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NIGDIANH_01269	411469.EUBHAL_03067	7.28e-250	690.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,25UTX@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NIGDIANH_01271	411469.EUBHAL_03069	1.88e-222	613.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VIC@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NIGDIANH_01272	411469.EUBHAL_03071	3.9e-38	127.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,25XS9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01273	411469.EUBHAL_03073	1.36e-34	118.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,25XSW@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4250)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NIGDIANH_01274	411469.EUBHAL_03075	2.49e-110	317.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,25W2J@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NIGDIANH_01275	411469.EUBHAL_03076	9.2e-306	833.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,25ZMR@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NIGDIANH_01276	411469.EUBHAL_00299	2.45e-53	167.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,25XFR@186806|Eubacteriaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NIGDIANH_01277	411469.EUBHAL_00300	1.5e-174	487.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,25XZV@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NIGDIANH_01278	411469.EUBHAL_00301	0.0	945.0	COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,248UV@186801|Clostridia,25VIB@186806|Eubacteriaceae	186801|Clostridia	O	MreB/Mbl protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
NIGDIANH_01279	411469.EUBHAL_00301	7.97e-37	136.0	COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,248UV@186801|Clostridia,25VIB@186806|Eubacteriaceae	186801|Clostridia	O	MreB/Mbl protein	-	-	-	ko:K04045	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
NIGDIANH_01280	411469.EUBHAL_00302	0.0	1268.0	COG2214@1|root,COG2214@2|Bacteria,1UJW2@1239|Firmicutes,25FBS@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_7,TPR_8
NIGDIANH_01281	411469.EUBHAL_00303	4.78e-96	283.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,25V15@186806|Eubacteriaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NIGDIANH_01282	411469.EUBHAL_02741	3.94e-41	135.0	2C4UR@1|root,33E7U@2|Bacteria,1W1BJ@1239|Firmicutes,24V2B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01283	411469.EUBHAL_02742	4.29e-116	332.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,25WAK@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NIGDIANH_01284	411469.EUBHAL_02743	1.45e-231	637.0	COG3608@1|root,COG3608@2|Bacteria,1TSBT@1239|Firmicutes,24A92@186801|Clostridia,25W37@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
NIGDIANH_01285	411469.EUBHAL_02744	3.15e-229	630.0	COG3608@1|root,COG3608@2|Bacteria,1UXZC@1239|Firmicutes,24BEB@186801|Clostridia,25W4G@186806|Eubacteriaceae	186801|Clostridia	S	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
NIGDIANH_01286	411461.DORFOR_02976	4.32e-87	264.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,27W3R@189330|Dorea	186801|Clostridia	S	Conserved hypothetical protein 698	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
NIGDIANH_01287	411461.DORFOR_02974	2.65e-247	678.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,27VG0@189330|Dorea	186801|Clostridia	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
NIGDIANH_01288	411461.DORFOR_02972	9.51e-215	597.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,27VVU@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NIGDIANH_01289	411461.DORFOR_02969	8.86e-116	332.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NIGDIANH_01290	411461.DORFOR_02967	2.35e-158	457.0	2E9EV@1|root,333N6@2|Bacteria,1VJBN@1239|Firmicutes,24WPB@186801|Clostridia,27WBD@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01291	411461.DORFOR_02967	3.04e-154	446.0	2E9EV@1|root,333N6@2|Bacteria,1VJBN@1239|Firmicutes,24WPB@186801|Clostridia,27WBD@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01292	411469.EUBHAL_00747	5.3e-294	805.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,25UT7@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
NIGDIANH_01293	411469.EUBHAL_00748	8.89e-143	402.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,25VZA@186806|Eubacteriaceae	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NIGDIANH_01294	411469.EUBHAL_00749	1.05e-75	226.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,25VEX@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
NIGDIANH_01295	411469.EUBHAL_00750	1.19e-191	532.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,25V64@186806|Eubacteriaceae	186801|Clostridia	S	TIGR00268 family	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
NIGDIANH_01297	411461.DORFOR_01547	2.82e-233	641.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,27UZD@189330|Dorea	186801|Clostridia	S	Radical_SAM C-terminal domain	-	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
NIGDIANH_01298	411461.DORFOR_01548	0.0	867.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,27XDK@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01299	411461.DORFOR_01549	9.79e-159	446.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,27UYD@189330|Dorea	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NIGDIANH_01300	411461.DORFOR_01551	7.76e-175	495.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,27V5I@189330|Dorea	186801|Clostridia	S	S4 RNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	S4
NIGDIANH_01301	411461.DORFOR_01552	8.24e-62	192.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,27VME@189330|Dorea	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NIGDIANH_01302	411469.EUBHAL_01171	0.0	1071.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	2.4.1.10,3.5.1.28	ko:K00692,ko:K01448,ko:K13730	ko00500,ko01100,ko01503,ko02020,ko05100,map00500,map01100,map01503,map02020,map05100	M00727	R04112,R05140	RC00064,RC00077,RC00141	ko00000,ko00001,ko00002,ko01000,ko01003,ko01011,ko03036	-	GH68	-	Big_2,CW_binding_2,ChW,LRR_4,LRR_5,fn3
NIGDIANH_01303	411469.EUBHAL_01170	0.0	1142.0	2DBD7@1|root,2Z8II@2|Bacteria,1UZG0@1239|Firmicutes,249JD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NIGDIANH_01304	411469.EUBHAL_01169	9.35e-312	849.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,25VPD@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
NIGDIANH_01305	411469.EUBHAL_01168	3.78e-132	375.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,25VMY@186806|Eubacteriaceae	186801|Clostridia	C	indolepyruvate ferredoxin oxidoreductase, beta subunit	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
NIGDIANH_01306	411469.EUBHAL_01095	3.26e-163	457.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,25VGE@186806|Eubacteriaceae	186801|Clostridia	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
NIGDIANH_01307	411469.EUBHAL_01094	0.0	1744.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,25UXM@186806|Eubacteriaceae	186801|Clostridia	J	Elongation factor G, domain IV	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NIGDIANH_01309	411469.EUBHAL_01092	1.66e-249	691.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25Y2B@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NIGDIANH_01310	411469.EUBHAL_01794	3.31e-195	540.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,24B3M@186801|Clostridia,25XGP@186806|Eubacteriaceae	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_01311	411469.EUBHAL_01793	6.9e-135	383.0	COG2197@1|root,COG2197@2|Bacteria,1UQ9Y@1239|Firmicutes,24EZU@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
NIGDIANH_01312	411469.EUBHAL_03110	0.0	1242.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25UR7@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HisKA,Hpt,MASE3,Response_reg
NIGDIANH_01314	411462.DORLON_00608	9.91e-42	151.0	COG0577@1|root,COG0577@2|Bacteria,1VU92@1239|Firmicutes,24YFJ@186801|Clostridia	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01315	411462.DORLON_00607	3.14e-178	496.0	COG1136@1|root,COG1136@2|Bacteria,1VQTV@1239|Firmicutes,24Y9N@186801|Clostridia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NIGDIANH_01317	411462.DORLON_00605	1.34e-279	764.0	COG4219@1|root,COG4219@2|Bacteria,1VCEX@1239|Firmicutes,24NT6@186801|Clostridia,27WUM@189330|Dorea	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NIGDIANH_01318	411462.DORLON_00604	6.37e-85	250.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24SJ3@186801|Clostridia,27WYK@189330|Dorea	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NIGDIANH_01319	1280698.AUJS01000075_gene2140	1.78e-38	129.0	290MC@1|root,2ZN9S@2|Bacteria,1W365@1239|Firmicutes,254RM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01320	411462.DORLON_00602	5.02e-227	626.0	COG1266@1|root,COG1266@2|Bacteria,1UZFC@1239|Firmicutes,24H55@186801|Clostridia,27VWG@189330|Dorea	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NIGDIANH_01321	411462.DORLON_00601	1.79e-77	230.0	COG0655@1|root,COG0655@2|Bacteria,1VBCI@1239|Firmicutes,25CJG@186801|Clostridia,27X6B@189330|Dorea	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NIGDIANH_01322	411462.DORLON_00600	9.47e-79	234.0	COG3587@1|root,COG3587@2|Bacteria,1TPRR@1239|Firmicutes,2488I@186801|Clostridia	186801|Clostridia	L	Type III restriction	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
NIGDIANH_01323	411469.EUBHAL_01544	0.0	1345.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
NIGDIANH_01324	411469.EUBHAL_01546	0.0	891.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,25VM5@186806|Eubacteriaceae	186801|Clostridia	M	Sulfatase	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
NIGDIANH_01325	411469.EUBHAL_01547	2.99e-160	452.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
NIGDIANH_01326	411469.EUBHAL_02846	3.81e-244	671.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,25V8X@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NIGDIANH_01327	411469.EUBHAL_01538	0.0	1880.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,25USS@186806|Eubacteriaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NIGDIANH_01328	411469.EUBHAL_01539	1.78e-253	708.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,25VKD@186806|Eubacteriaceae	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NIGDIANH_01329	411469.EUBHAL_01281	2.45e-290	791.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,25VKE@186806|Eubacteriaceae	186801|Clostridia	F	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NIGDIANH_01330	411469.EUBHAL_01280	2.31e-172	480.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,25V2N@186806|Eubacteriaceae	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
NIGDIANH_01332	1094980.Mpsy_1641	3.61e-27	108.0	COG1437@1|root,arCOG01723@2157|Archaea,2XYQS@28890|Euryarchaeota,2N9TV@224756|Methanomicrobia	224756|Methanomicrobia	F	adenylyl cyclase CyaB	cyaB	-	4.6.1.1	ko:K05873	ko00230,map00230	-	R00089,R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	CYTH
NIGDIANH_01333	411469.EUBHAL_01278	4.43e-217	600.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,25VJC@186806|Eubacteriaceae	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NIGDIANH_01334	411469.EUBHAL_01267	0.0	1041.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,25VZ3@186806|Eubacteriaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NIGDIANH_01335	411469.EUBHAL_01266	1.31e-184	514.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,25WAU@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NIGDIANH_01336	411469.EUBHAL_01265	7.84e-214	592.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,25VK1@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NIGDIANH_01337	411461.DORFOR_01093	4.31e-260	718.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,27V8F@189330|Dorea	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
NIGDIANH_01338	411461.DORFOR_01094	2.21e-275	753.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,27V4F@189330|Dorea	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NIGDIANH_01339	411461.DORFOR_01095	5.01e-256	730.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,27VEQ@189330|Dorea	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NIGDIANH_01340	411461.DORFOR_01095	8.56e-228	651.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,27VEQ@189330|Dorea	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NIGDIANH_01341	411469.EUBHAL_02960	1.61e-33	122.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,25VZK@186806|Eubacteriaceae	186801|Clostridia	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NIGDIANH_01343	411469.EUBHAL_02962	3.86e-188	521.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,25V81@186806|Eubacteriaceae	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NIGDIANH_01344	411469.EUBHAL_02963	9.11e-220	608.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,25ZU6@186806|Eubacteriaceae	186801|Clostridia	I	Stage V sporulation protein AD (SpoVAD)	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NIGDIANH_01345	411469.EUBHAL_02964	3.41e-73	220.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,25WI2@186806|Eubacteriaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NIGDIANH_01346	411469.EUBHAL_02965	1.39e-232	640.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRD9@1239|Firmicutes,24CDE@186801|Clostridia,25YMQ@186806|Eubacteriaceae	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NIGDIANH_01347	411469.EUBHAL_02966	1.4e-166	474.0	COG2972@1|root,COG4936@1|root,COG2972@2|Bacteria,COG4936@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25YR9@186806|Eubacteriaceae	186801|Clostridia	T	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,PocR
NIGDIANH_01348	411469.EUBHAL_02653	3.44e-190	536.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,25VSM@186806|Eubacteriaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_01349	411469.EUBHAL_02651	2.08e-152	427.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,25VHV@186806|Eubacteriaceae	186801|Clostridia	H	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
NIGDIANH_01350	411469.EUBHAL_02650	8.6e-292	796.0	COG1879@1|root,COG2199@1|root,COG1879@2|Bacteria,COG3706@2|Bacteria,1UK20@1239|Firmicutes,25FNV@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NIGDIANH_01351	411469.EUBHAL_02649	6.92e-155	434.0	COG2304@1|root,COG2304@2|Bacteria,1TRPP@1239|Firmicutes,249HV@186801|Clostridia,25VGG@186806|Eubacteriaceae	186801|Clostridia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01352	411469.EUBHAL_02993	2.25e-241	663.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,25UV0@186806|Eubacteriaceae	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
NIGDIANH_01353	411469.EUBHAL_02091	1.31e-76	235.0	2CA85@1|root,343NM@2|Bacteria,1VPNT@1239|Firmicutes,24V7K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01354	411469.EUBHAL_02090	0.0	881.0	COG1541@1|root,COG1541@2|Bacteria,1TUII@1239|Firmicutes,25876@186801|Clostridia,25Z2B@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	-
NIGDIANH_01355	411469.EUBHAL_02089	0.0	922.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,25WI4@186806|Eubacteriaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
NIGDIANH_01356	411469.EUBHAL_02087	6.75e-289	788.0	COG0151@1|root,COG0151@2|Bacteria,1UINU@1239|Firmicutes,25EPG@186801|Clostridia,25ZUJ@186806|Eubacteriaceae	186801|Clostridia	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NIGDIANH_01357	411469.EUBHAL_01245	4.16e-177	493.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,25VD6@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NIGDIANH_01358	411469.EUBHAL_01246	8.48e-175	489.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,25W3G@186806|Eubacteriaceae	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NIGDIANH_01359	411469.EUBHAL_01247	2.43e-263	722.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,25UXN@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NIGDIANH_01360	411469.EUBHAL_01248	9.79e-235	647.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,25VUG@186806|Eubacteriaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NIGDIANH_01361	658655.HMPREF0988_02765	0.0	916.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,27IFR@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
NIGDIANH_01362	1226325.HMPREF1548_01187	2.1e-187	546.0	COG3507@1|root,COG3507@2|Bacteria,1UIN7@1239|Firmicutes,24CH5@186801|Clostridia,36VM2@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NIGDIANH_01363	411469.EUBHAL_02925	7.83e-127	362.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,25YJ5@186806|Eubacteriaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NIGDIANH_01364	411469.EUBHAL_02924	6.34e-156	438.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,25WQ1@186806|Eubacteriaceae	186801|Clostridia	K	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NIGDIANH_01365	411469.EUBHAL_02923	3.51e-74	222.0	COG1917@1|root,COG1917@2|Bacteria,1V6IB@1239|Firmicutes,24JTU@186801|Clostridia,25WYX@186806|Eubacteriaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NIGDIANH_01366	411469.EUBHAL_02922	0.0	1080.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,25V33@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	DUF1858,Prismane
NIGDIANH_01367	411469.EUBHAL_01122	3.8e-304	833.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,25VDE@186806|Eubacteriaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NIGDIANH_01368	411469.EUBHAL_03139	0.0	1922.0	COG2340@1|root,COG3867@1|root,COG2340@2|Bacteria,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia,25YHG@186806|Eubacteriaceae	186801|Clostridia	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CW_binding_1,Glyco_hydro_53
NIGDIANH_01369	411469.EUBHAL_00559	2.68e-252	691.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,25V2I@186806|Eubacteriaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NIGDIANH_01370	411469.EUBHAL_00560	0.0	1111.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_2
NIGDIANH_01372	411469.EUBHAL_00561	5.59e-90	263.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia,25ZDY@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01374	411469.EUBHAL_00563	2.1e-134	380.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24I8Z@186801|Clostridia,25WCP@186806|Eubacteriaceae	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	-	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
NIGDIANH_01375	411469.EUBHAL_02262	8.19e-46	147.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,25X8C@186806|Eubacteriaceae	186801|Clostridia	K	'Cold-shock' DNA-binding domain	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NIGDIANH_01376	411469.EUBHAL_02261	8.14e-264	724.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,25WGC@186806|Eubacteriaceae	186801|Clostridia	S	AI-2E family transporter	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NIGDIANH_01377	411469.EUBHAL_02260	3.89e-212	587.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,25W92@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01378	411469.EUBHAL_02258	4.62e-107	309.0	2E62H@1|root,330RM@2|Bacteria,1VEY2@1239|Firmicutes,24T93@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01379	411469.EUBHAL_02257	1.21e-40	134.0	COG2155@1|root,COG2155@2|Bacteria,1VEQJ@1239|Firmicutes,24QKW@186801|Clostridia,25X9C@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NIGDIANH_01380	411469.EUBHAL_02255	2.84e-137	389.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia,25XJR@186806|Eubacteriaceae	186801|Clostridia	F	ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
NIGDIANH_01381	411469.EUBHAL_01072	5.1e-302	824.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,25VN6@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NIGDIANH_01382	411469.EUBHAL_01073	0.0	1030.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,25VII@186806|Eubacteriaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NIGDIANH_01383	411469.EUBHAL_01074	5.32e-167	467.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,25UYN@186806|Eubacteriaceae	186801|Clostridia	E	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_01384	411469.EUBHAL_02038	0.0	1002.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NIGDIANH_01385	411469.EUBHAL_02037	3.29e-259	710.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,25UYK@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_01386	411469.EUBHAL_02036	2.65e-246	677.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,25V56@186806|Eubacteriaceae	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NIGDIANH_01387	411469.EUBHAL_02035	3.48e-213	588.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,25W1H@186806|Eubacteriaceae	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NIGDIANH_01388	411469.EUBHAL_02034	1.3e-58	189.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,25URQ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1385)	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NIGDIANH_01389	411470.RUMGNA_02829	2.94e-196	575.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3Y0EJ@572511|Blautia	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH
NIGDIANH_01391	411470.RUMGNA_02828	1.37e-109	330.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3Y0R0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Sortase,YibE_F
NIGDIANH_01392	411469.EUBHAL_02823	7.85e-242	665.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,25VBJ@186806|Eubacteriaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
NIGDIANH_01393	411469.EUBHAL_02971	1.59e-202	564.0	COG1376@1|root,COG1376@2|Bacteria,1UK0I@1239|Firmicutes,249X8@186801|Clostridia,25W21@186806|Eubacteriaceae	186801|Clostridia	V	L,D-transpeptidase catalytic domain	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	DUF5011,YkuD
NIGDIANH_01394	411469.EUBHAL_02972	0.0	1681.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,25V0K@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NIGDIANH_01395	411469.EUBHAL_02973	4.3e-44	142.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NIGDIANH_01396	411469.EUBHAL_03289	0.0	952.0	COG1142@1|root,COG4624@1|root,COG1142@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,25VE9@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NIGDIANH_01397	411469.EUBHAL_03288	2.85e-316	861.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,25URH@186806|Eubacteriaceae	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NIGDIANH_01399	411469.EUBHAL_03283	1.17e-125	358.0	2EACE@1|root,334GC@2|Bacteria,1VJGH@1239|Firmicutes,24T7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01400	411469.EUBHAL_01274	5.79e-37	133.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,25UX8@186806|Eubacteriaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	dhaD	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NIGDIANH_01401	411469.EUBHAL_01275	8.83e-99	315.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NIGDIANH_01402	411469.EUBHAL_01275	1.59e-91	296.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NIGDIANH_01403	411469.EUBHAL_01275	0.0	1201.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NIGDIANH_01404	411469.EUBHAL_01276	8.63e-295	803.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NIGDIANH_01405	537007.BLAHAN_05246	2.61e-112	367.0	2DP05@1|root,33004@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01410	411469.EUBHAL_03015	1.52e-291	799.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,25UQN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
NIGDIANH_01411	411469.EUBHAL_03016	1.15e-185	515.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,25W7P@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NIGDIANH_01412	411469.EUBHAL_03017	5.87e-255	699.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,25VC9@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NIGDIANH_01413	411469.EUBHAL_03018	0.0	1105.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,25VFE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NIGDIANH_01414	478749.BRYFOR_09005	6.03e-75	227.0	COG1396@1|root,COG1396@2|Bacteria,1UYE6@1239|Firmicutes,24CI9@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NIGDIANH_01416	1304866.K413DRAFT_4958	0.0	907.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,36EFK@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NIGDIANH_01417	742740.HMPREF9474_03103	3.65e-81	264.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,21Z5N@1506553|Lachnoclostridium	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NIGDIANH_01418	411469.EUBHAL_03063	3.08e-41	154.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,25W6W@186806|Eubacteriaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NIGDIANH_01419	411469.EUBHAL_03063	1.09e-166	489.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,25W6W@186806|Eubacteriaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NIGDIANH_01420	411469.EUBHAL_03064	1.01e-178	498.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,25VJW@186806|Eubacteriaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,FtsX
NIGDIANH_01421	411469.EUBHAL_01392	2.61e-81	249.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,25V4G@186806|Eubacteriaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
NIGDIANH_01422	411469.EUBHAL_01393	2.97e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1UQJ3@1239|Firmicutes,258AR@186801|Clostridia,25XPZ@186806|Eubacteriaceae	186801|Clostridia	H	ThiS family	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
NIGDIANH_01423	411469.EUBHAL_01394	1.14e-177	495.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,25VDI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NIGDIANH_01424	411469.EUBHAL_01395	2.64e-305	832.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,25VR3@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NIGDIANH_01425	411469.EUBHAL_01396	1.97e-100	295.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,25WPB@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
NIGDIANH_01426	411469.EUBHAL_01397	3.49e-173	484.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,25WFN@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
NIGDIANH_01427	411469.EUBHAL_01554	4.3e-185	514.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,25WIY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
NIGDIANH_01428	411469.EUBHAL_01553	2.16e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,25Y2G@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NIGDIANH_01429	411469.EUBHAL_01552	1.32e-218	602.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,25Y9K@186806|Eubacteriaceae	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NIGDIANH_01430	411469.EUBHAL_01551	2.43e-221	615.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,25W6E@186806|Eubacteriaceae	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
NIGDIANH_01431	411469.EUBHAL_02233	4e-183	510.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,25W82@186806|Eubacteriaceae	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NIGDIANH_01432	411469.EUBHAL_02234	2.97e-125	355.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NIGDIANH_01433	411469.EUBHAL_02235	6.41e-197	545.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,25W20@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the pyridoxine kinase family	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
NIGDIANH_01434	411469.EUBHAL_02236	1.02e-163	457.0	COG0535@1|root,COG0535@2|Bacteria,1V3MC@1239|Firmicutes,24I1P@186801|Clostridia,25ZK5@186806|Eubacteriaceae	186801|Clostridia	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
NIGDIANH_01435	903814.ELI_0053	8.14e-158	456.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	5.1.3.38	ko:K21909	-	-	-	-	ko00000,ko01000	-	-	-	AP_endonuc_2
NIGDIANH_01436	903814.ELI_0054	4.72e-200	560.0	COG1063@1|root,COG1063@2|Bacteria,1U9ZD@1239|Firmicutes,24EJR@186801|Clostridia,25YI6@186806|Eubacteriaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NIGDIANH_01437	903814.ELI_0046	2.32e-88	270.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,25VIJ@186806|Eubacteriaceae	186801|Clostridia	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NIGDIANH_01438	411469.EUBHAL_00231	3.5e-81	240.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,25VIJ@186806|Eubacteriaceae	186801|Clostridia	E	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NIGDIANH_01439	411469.EUBHAL_00232	4.15e-185	514.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,25VPM@186806|Eubacteriaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
NIGDIANH_01440	411469.EUBHAL_03241	1.03e-243	670.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,25VDT@186806|Eubacteriaceae	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NIGDIANH_01441	411469.EUBHAL_03242	0.0	1040.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,25V23@186806|Eubacteriaceae	186801|Clostridia	P	Na Pi-cotransporter II-like protein	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NIGDIANH_01442	411469.EUBHAL_03243	1.26e-215	595.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,25W73@186806|Eubacteriaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NIGDIANH_01443	411469.EUBHAL_03244	1.97e-113	326.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,25X3Y@186806|Eubacteriaceae	186801|Clostridia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NIGDIANH_01444	411469.EUBHAL_00375	8.38e-98	284.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,25W8D@186806|Eubacteriaceae	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NIGDIANH_01445	411469.EUBHAL_00374	1.48e-220	608.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,25V8D@186806|Eubacteriaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NIGDIANH_01446	411469.EUBHAL_00373	1.22e-221	610.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,25WE6@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	Acetyltransf_3,DUF2156
NIGDIANH_01447	411469.EUBHAL_00372	3.38e-296	808.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,25VFN@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NIGDIANH_01448	411469.EUBHAL_00371	1.28e-99	289.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,25WGK@186806|Eubacteriaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NIGDIANH_01449	411469.EUBHAL_02667	2.25e-232	645.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NIGDIANH_01450	411469.EUBHAL_02667	4.86e-108	323.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NIGDIANH_01451	411469.EUBHAL_02669	0.0	1145.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,25V20@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NIGDIANH_01452	411469.EUBHAL_02670	4.08e-95	278.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia,25XEW@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
NIGDIANH_01454	411469.EUBHAL_03118	3.14e-127	362.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,25W16@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NIGDIANH_01455	411469.EUBHAL_03119	1.03e-201	558.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,25VS3@186806|Eubacteriaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2,4.2.1.32	ko:K01677,ko:K03779	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NIGDIANH_01456	411469.EUBHAL_03120	0.0	1556.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,25UZ0@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NIGDIANH_01457	411469.EUBHAL_03121	3.37e-77	246.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,25VFV@186806|Eubacteriaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NIGDIANH_01458	411469.EUBHAL_00593	3.58e-207	573.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,25VAY@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NIGDIANH_01459	411469.EUBHAL_00594	7.87e-243	667.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,25VT1@186806|Eubacteriaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NIGDIANH_01460	411469.EUBHAL_00595	1.06e-145	410.0	COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,24HHC@186801|Clostridia,25WNR@186806|Eubacteriaceae	186801|Clostridia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
NIGDIANH_01461	411469.EUBHAL_00596	0.0	1016.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,25VF6@186806|Eubacteriaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NIGDIANH_01462	411469.EUBHAL_01837	7.93e-47	151.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25XFI@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NIGDIANH_01463	411469.EUBHAL_01838	5.6e-222	612.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,25V3S@186806|Eubacteriaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
NIGDIANH_01464	411469.EUBHAL_01839	1.38e-213	594.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,25UTM@186806|Eubacteriaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NIGDIANH_01465	411469.EUBHAL_01839	3.63e-63	203.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,25UTM@186806|Eubacteriaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NIGDIANH_01466	411469.EUBHAL_01840	1.34e-232	641.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,25V4D@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
NIGDIANH_01467	411469.EUBHAL_00846	2.45e-288	787.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,25URE@186806|Eubacteriaceae	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NIGDIANH_01469	411469.EUBHAL_00848	4.23e-99	288.0	COG1576@1|root,COG1576@2|Bacteria	2|Bacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	MDMPI_N,SPOUT_MTase
NIGDIANH_01470	411469.EUBHAL_00850	1.9e-109	315.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,25WEA@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score 8.87	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
NIGDIANH_01471	411469.EUBHAL_00852	2.81e-215	600.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,25UY5@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.2,1.4.1.3,1.4.1.4	ko:K00260,ko:K00261,ko:K00262	ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NIGDIANH_01472	1235798.C817_03531	1.46e-26	102.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,27W7S@189330|Dorea	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
NIGDIANH_01473	742765.HMPREF9457_01457	6.28e-69	218.0	COG1464@1|root,COG1464@2|Bacteria,1VASX@1239|Firmicutes,24GXY@186801|Clostridia,27XAD@189330|Dorea	186801|Clostridia	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NIGDIANH_01474	471855.Shel_19570	1.54e-35	128.0	COG1464@1|root,COG1464@2|Bacteria,2GMNI@201174|Actinobacteria,4CXA9@84998|Coriobacteriia	84998|Coriobacteriia	P	NLPA lipoprotein	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NIGDIANH_01475	1449050.JNLE01000003_gene1080	4.48e-81	254.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,25CBA@186801|Clostridia,36WSU@31979|Clostridiaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NIGDIANH_01476	742765.HMPREF9457_01458	4.05e-267	730.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,25NJY@186801|Clostridia,27W9W@189330|Dorea	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NIGDIANH_01477	457421.CBFG_04796	7.5e-130	400.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15,AAA_21
NIGDIANH_01478	913865.DOT_4225	1.56e-132	377.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,262BG@186807|Peptococcaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
NIGDIANH_01479	1069534.LRC_01130	2.45e-196	546.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli,3F4QS@33958|Lactobacillaceae	91061|Bacilli	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NIGDIANH_01480	1256908.HMPREF0373_00136	2.75e-251	689.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,25VJ0@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NIGDIANH_01481	411469.EUBHAL_01317	2.13e-63	194.0	2DQ36@1|root,334JH@2|Bacteria,1VF6I@1239|Firmicutes,24TEH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NIGDIANH_01482	411469.EUBHAL_01316	0.0	895.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,25V89@186806|Eubacteriaceae	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NIGDIANH_01483	411469.EUBHAL_01315	7.39e-312	849.0	COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,248HT@186801|Clostridia,25XFF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
NIGDIANH_01484	411469.EUBHAL_01314	1.06e-287	816.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,25ZK1@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
NIGDIANH_01485	411469.EUBHAL_00921	0.0	1305.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,25VBG@186806|Eubacteriaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NIGDIANH_01486	411469.EUBHAL_00922	0.0	1189.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,25VWB@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NIGDIANH_01487	411469.EUBHAL_01251	2.92e-122	380.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,25VUB@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NIGDIANH_01488	411469.EUBHAL_01252	0.0	1017.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,25UTH@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NIGDIANH_01489	411469.EUBHAL_01253	1.19e-104	306.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,25VX0@186806|Eubacteriaceae	186801|Clostridia	S	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NIGDIANH_01490	411469.EUBHAL_01254	5.96e-207	572.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,25UQP@186806|Eubacteriaceae	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NIGDIANH_01492	411469.EUBHAL_00271	1.86e-93	273.0	COG1989@1|root,COG1989@2|Bacteria,1VEVI@1239|Firmicutes	1239|Firmicutes	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
NIGDIANH_01494	411469.EUBHAL_01501	3.15e-161	451.0	COG2964@1|root,COG2964@2|Bacteria,1V2VD@1239|Firmicutes,24GH7@186801|Clostridia,25WMD@186806|Eubacteriaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NIGDIANH_01495	411469.EUBHAL_01502	7.15e-165	461.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia,25ZK3@186806|Eubacteriaceae	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
NIGDIANH_01496	411469.EUBHAL_01504	2.07e-221	616.0	COG0803@1|root,COG0803@2|Bacteria,1TPG7@1239|Firmicutes,249VZ@186801|Clostridia,25VJF@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, substrate-binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
NIGDIANH_01497	411469.EUBHAL_01505	1.17e-169	474.0	COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,248F1@186801|Clostridia,25W5W@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
NIGDIANH_01498	411469.EUBHAL_02379	1.56e-109	316.0	2E3U8@1|root,32YRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NIGDIANH_01499	411469.EUBHAL_02377	6.76e-218	602.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,25UQQ@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NIGDIANH_01500	411469.EUBHAL_02376	3.38e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,25VYR@186806|Eubacteriaceae	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.40	ko:K09693	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.104	-	-	ABC_tran
NIGDIANH_01501	411469.EUBHAL_02375	3.39e-181	504.0	COG1682@1|root,COG1682@2|Bacteria,1UZ1K@1239|Firmicutes,24DBF@186801|Clostridia,25UVJ@186806|Eubacteriaceae	186801|Clostridia	U	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
NIGDIANH_01502	1280698.AUJS01000084_gene2431	0.0	1438.0	COG2936@1|root,COG2936@2|Bacteria,1TT0H@1239|Firmicutes,25993@186801|Clostridia,27WX4@189330|Dorea	186801|Clostridia	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PepX_C,Peptidase_S15
NIGDIANH_01503	1280698.AUJS01000084_gene2430	3.68e-295	806.0	COG2271@1|root,COG2271@2|Bacteria,1UZ2K@1239|Firmicutes,2493E@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NIGDIANH_01504	1522092.A0A090DBU6_9CAUD	3.17e-122	372.0	4QDE3@10239|Viruses,4QU4B@28883|Caudovirales,4QICQ@10662|Myoviridae	10662|Myoviridae	S	hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01506	448385.sce6698	4.68e-09	63.9	COG0457@1|root,COG0457@2|Bacteria,1R8JA@1224|Proteobacteria,42VM8@68525|delta/epsilon subdivisions,2WY1E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01507	411469.EUBHAL_02099	1.88e-79	237.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,25XUH@186806|Eubacteriaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NIGDIANH_01508	411469.EUBHAL_02100	2.08e-289	789.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,25V1E@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NIGDIANH_01509	411469.EUBHAL_02101	1.75e-131	374.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,25V8Q@186806|Eubacteriaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NIGDIANH_01510	411469.EUBHAL_02102	9.14e-127	360.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,25WR2@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NIGDIANH_01511	411469.EUBHAL_02103	0.0	877.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,25UTK@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NIGDIANH_01513	411461.DORFOR_00988	1.43e-125	356.0	COG0457@1|root,COG0457@2|Bacteria,1VDUM@1239|Firmicutes,24NK8@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01516	411469.EUBHAL_00702	1.63e-114	335.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,25W1E@186806|Eubacteriaceae	186801|Clostridia	P	Helix-turn-helix domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
NIGDIANH_01517	411469.EUBHAL_00703	2.88e-189	527.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,25WJQ@186806|Eubacteriaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NIGDIANH_01518	411469.EUBHAL_00704	8.27e-150	422.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,25WH2@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NIGDIANH_01519	411469.EUBHAL_00705	2.24e-262	719.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,25VJJ@186806|Eubacteriaceae	186801|Clostridia	P	ATPases associated with a variety of cellular activities	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NIGDIANH_01520	411469.EUBHAL_00706	2.39e-228	628.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,25ZQY@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_01521	411469.EUBHAL_01441	6.02e-186	518.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,25VHF@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NIGDIANH_01522	411469.EUBHAL_01440	2.47e-215	600.0	COG0860@1|root,COG0860@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,25X2G@186806|Eubacteriaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
NIGDIANH_01525	411469.EUBHAL_01437	4.72e-138	399.0	COG1033@1|root,COG1033@2|Bacteria,1VHSF@1239|Firmicutes,24R7H@186801|Clostridia,25XTN@186806|Eubacteriaceae	186801|Clostridia	M	YARHG domain	-	-	-	-	-	-	-	-	-	-	-	-	YARHG,zinc_ribbon_2
NIGDIANH_01526	411469.EUBHAL_03265	5.29e-32	122.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,25VE5@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NIGDIANH_01527	411469.EUBHAL_03098	1.62e-238	658.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia,25XU8@186806|Eubacteriaceae	186801|Clostridia	S	CAAX amino terminal protease family	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NIGDIANH_01528	411469.EUBHAL_03097	3.3e-199	552.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,25VSX@186806|Eubacteriaceae	186801|Clostridia	S	S1 domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
NIGDIANH_01529	411469.EUBHAL_03096	7.74e-172	479.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,25WPJ@186806|Eubacteriaceae	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NIGDIANH_01530	411469.EUBHAL_03095	2.35e-67	204.0	2DQFX@1|root,336KU@2|Bacteria,1VP58@1239|Firmicutes,25HKT@186801|Clostridia	186801|Clostridia	S	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_01532	411469.EUBHAL_02055	1.43e-63	201.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,25VC8@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
NIGDIANH_01533	411469.EUBHAL_02054	1.28e-297	811.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,25VP8@186806|Eubacteriaceae	186801|Clostridia	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NIGDIANH_01534	411469.EUBHAL_02053	2.06e-190	530.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,25USE@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NIGDIANH_01535	411469.EUBHAL_02052	1.64e-114	328.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,25WMB@186806|Eubacteriaceae	186801|Clostridia	S	HTH domain protein	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NIGDIANH_01536	411469.EUBHAL_02050	3.29e-192	533.0	COG0789@1|root,COG0789@2|Bacteria,1UFKB@1239|Firmicutes,24NU1@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR
NIGDIANH_01537	411469.EUBHAL_02070	1.3e-58	182.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,25X2A@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
NIGDIANH_01538	411469.EUBHAL_02071	2.36e-56	175.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,25WUG@186806|Eubacteriaceae	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NIGDIANH_01539	411469.EUBHAL_02072	1.18e-46	150.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,25XAD@186806|Eubacteriaceae	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NIGDIANH_01540	411469.EUBHAL_02073	4.82e-121	346.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,25WA1@186806|Eubacteriaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NIGDIANH_01541	411469.EUBHAL_02074	3.45e-265	726.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia,25VCD@186806|Eubacteriaceae	186801|Clostridia	I	Pfam:DUF2424	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
NIGDIANH_01542	411469.EUBHAL_02075	5.46e-185	514.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia,25X3I@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01543	411469.EUBHAL_02076	1.89e-40	144.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,25VYV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NIGDIANH_01544	411469.EUBHAL_01530	1.57e-54	178.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,25V0Y@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NIGDIANH_01545	411469.EUBHAL_01531	2.48e-135	384.0	COG4659@1|root,COG4659@2|Bacteria,1V4CE@1239|Firmicutes,25CQS@186801|Clostridia,25ZJ7@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NIGDIANH_01546	411469.EUBHAL_01532	2.81e-161	453.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25VAT@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
NIGDIANH_01547	411469.EUBHAL_01533	8.37e-116	333.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,25VXE@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NIGDIANH_01548	411469.EUBHAL_01534	2.12e-181	505.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,25VDB@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NIGDIANH_01549	411469.EUBHAL_01535	2.52e-239	656.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,25UU9@186806|Eubacteriaceae	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
NIGDIANH_01550	411469.EUBHAL_01737	1.91e-117	339.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,25UQE@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NIGDIANH_01551	411469.EUBHAL_01738	6.15e-62	189.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,25WMJ@186806|Eubacteriaceae	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NIGDIANH_01552	411469.EUBHAL_01739	7.74e-86	253.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,25WWP@186806|Eubacteriaceae	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NIGDIANH_01553	411469.EUBHAL_01740	2.14e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,25VHR@186806|Eubacteriaceae	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NIGDIANH_01554	411469.EUBHAL_01741	1.22e-102	296.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,25W3Z@186806|Eubacteriaceae	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NIGDIANH_01555	411469.EUBHAL_01742	1.3e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,25XGM@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NIGDIANH_01556	411469.EUBHAL_01743	2.67e-52	164.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25WUN@186806|Eubacteriaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NIGDIANH_01557	411469.EUBHAL_01744	4.41e-80	238.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,25WCX@186806|Eubacteriaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NIGDIANH_01558	411469.EUBHAL_01745	3.67e-65	198.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,25WQ0@186806|Eubacteriaceae	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NIGDIANH_01559	411469.EUBHAL_01746	1.39e-124	355.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,25V67@186806|Eubacteriaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NIGDIANH_01560	411469.EUBHAL_01747	2.83e-28	102.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,25X7N@186806|Eubacteriaceae	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NIGDIANH_01561	411469.EUBHAL_01872	6.77e-35	121.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,25X0I@186806|Eubacteriaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NIGDIANH_01562	411469.EUBHAL_01873	0.0	1543.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,25UXY@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NIGDIANH_01566	411469.EUBHAL_03279	3.06e-303	825.0	COG0515@1|root,COG0515@2|Bacteria,1W0HH@1239|Firmicutes,252VD@186801|Clostridia	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
NIGDIANH_01567	411469.EUBHAL_03278	4.91e-136	389.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NIGDIANH_01568	411469.EUBHAL_02959	1.64e-203	563.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NIGDIANH_01569	411469.EUBHAL_02957	1.9e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,25W0I@186806|Eubacteriaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01570	411469.EUBHAL_02956	3.31e-263	722.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,25V5C@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_01571	411469.EUBHAL_02955	4.56e-104	300.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,25WKZ@186806|Eubacteriaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NIGDIANH_01572	411469.EUBHAL_01108	1.9e-127	362.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,25VDD@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NIGDIANH_01573	411469.EUBHAL_01106	9.45e-126	357.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,25W1X@186806|Eubacteriaceae	186801|Clostridia	E	ethanolamine utilization protein EutP	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NIGDIANH_01574	411469.EUBHAL_01105	5.32e-159	446.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,25WEE@186806|Eubacteriaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NIGDIANH_01575	411469.EUBHAL_01104	3.62e-217	600.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,25WVD@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NIGDIANH_01576	411469.EUBHAL_01103	3.02e-102	296.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NIGDIANH_01577	411469.EUBHAL_02931	2.17e-306	834.0	COG0665@1|root,COG0665@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia,25WB3@186806|Eubacteriaceae	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
NIGDIANH_01578	411469.EUBHAL_02930	0.0	1107.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia,25VMT@186806|Eubacteriaceae	186801|Clostridia	P	COG0659 Sulfate permease and related transporters (MFS superfamily)	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
NIGDIANH_01579	622312.ROSEINA2194_00353	1.09e-253	702.0	28ISM@1|root,2Z8RR@2|Bacteria,1TQK6@1239|Firmicutes,24AHH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01580	622312.ROSEINA2194_00351	2.27e-119	340.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
NIGDIANH_01581	622312.ROSEINA2194_00352	0.0	1207.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NIGDIANH_01582	411461.DORFOR_02977	8.18e-211	582.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,27W7Q@189330|Dorea	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01583	411461.DORFOR_02978	4.26e-104	305.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,25A4Z@186801|Clostridia,27V6Z@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NIGDIANH_01584	411461.DORFOR_02979	3.09e-56	174.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,27WXS@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01585	411461.DORFOR_02980	3.44e-70	211.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia,27X4P@189330|Dorea	186801|Clostridia	E	Branched-chain amino acid transport protein (AzlD)	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
NIGDIANH_01586	742765.HMPREF9457_02628	3.58e-269	736.0	COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,248U0@186801|Clostridia,27W7I@189330|Dorea	186801|Clostridia	E	COG COG0620 MeTHIonine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
NIGDIANH_01587	411469.EUBHAL_00662	8.73e-114	325.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,25WKI@186806|Eubacteriaceae	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NIGDIANH_01588	411469.EUBHAL_00663	8.21e-198	551.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,25ZPN@186806|Eubacteriaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NIGDIANH_01589	411469.EUBHAL_00664	1.3e-99	290.0	COG4393@1|root,COG4393@2|Bacteria,1V670@1239|Firmicutes,24HZF@186801|Clostridia	186801|Clostridia	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
NIGDIANH_01590	411469.EUBHAL_00665	4.16e-314	859.0	COG2836@1|root,COG4633@1|root,COG2836@2|Bacteria,COG4633@2|Bacteria,1TQ02@1239|Firmicutes,249HC@186801|Clostridia	186801|Clostridia	P	Heavy metal transport detoxification protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
NIGDIANH_01591	1121115.AXVN01000071_gene3938	4.28e-38	141.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3XYUV@572511|Blautia	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
NIGDIANH_01592	138119.DSY3851	8.06e-86	283.0	COG1129@1|root,COG4720@1|root,COG1129@2|Bacteria,COG4720@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,267B9@186807|Peptococcaceae	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
NIGDIANH_01593	357809.Cphy_0955	2.91e-82	259.0	COG1082@1|root,COG1082@2|Bacteria,1U2VB@1239|Firmicutes,24EE7@186801|Clostridia	186801|Clostridia	G	PFAM Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NIGDIANH_01594	411469.EUBHAL_02635	3.07e-156	437.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,25WAA@186806|Eubacteriaceae	186801|Clostridia	F	orotate phosphoribosyltransferase K00762	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NIGDIANH_01595	411469.EUBHAL_00673	7.27e-206	568.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NIGDIANH_01596	411469.EUBHAL_00674	7.77e-218	602.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,25XB8@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01597	411469.EUBHAL_02332	1.61e-262	720.0	COG0642@1|root,COG2205@2|Bacteria,1V129@1239|Firmicutes,25EBE@186801|Clostridia,25ZK6@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_01598	411469.EUBHAL_02333	4.03e-148	418.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,25VMJ@186806|Eubacteriaceae	186801|Clostridia	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01599	411469.EUBHAL_02707	1.12e-196	550.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,25UU2@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_01600	411469.EUBHAL_02707	7.49e-17	78.6	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,25UU2@186806|Eubacteriaceae	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_01601	411469.EUBHAL_02706	4.49e-208	575.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,25VMV@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NIGDIANH_01602	411469.EUBHAL_02705	1.42e-118	340.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,25WNT@186806|Eubacteriaceae	186801|Clostridia	K	ANTAR domain	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
NIGDIANH_01603	411469.EUBHAL_02704	1.46e-257	710.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,25VDK@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NIGDIANH_01604	411461.DORFOR_02615	2.56e-72	217.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,27VP3@189330|Dorea	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NIGDIANH_01605	411461.DORFOR_02614	2.29e-20	81.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,27VX5@189330|Dorea	186801|Clostridia	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NIGDIANH_01606	411461.DORFOR_02612	0.0	909.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,27VGE@189330|Dorea	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NIGDIANH_01607	411461.DORFOR_02610	2.14e-257	706.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,27V5V@189330|Dorea	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NIGDIANH_01608	411461.DORFOR_02609	7.4e-41	134.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,27VVE@189330|Dorea	186801|Clostridia	S	S4 domain	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NIGDIANH_01609	411469.EUBHAL_03250	0.0	1480.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,25UWY@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
NIGDIANH_01610	411469.EUBHAL_03251	0.0	1018.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,25VHD@186806|Eubacteriaceae	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
NIGDIANH_01611	658088.HMPREF0987_01037	0.0	976.0	COG0286@1|root,COG3177@1|root,COG0286@2|Bacteria,COG3177@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,27KD4@186928|unclassified Lachnospiraceae	186801|Clostridia	V	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NIGDIANH_01612	457412.RSAG_00262	5.38e-196	550.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WG95@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NIGDIANH_01613	411461.DORFOR_02208	1.21e-106	308.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia,27WQ0@189330|Dorea	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NIGDIANH_01614	742765.HMPREF9457_02977	7.33e-152	428.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,27WBF@189330|Dorea	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NIGDIANH_01615	411469.EUBHAL_01471	4.22e-174	486.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,25VC1@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
NIGDIANH_01616	411469.EUBHAL_01470	6.27e-240	673.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,25V5P@186806|Eubacteriaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
NIGDIANH_01617	1235802.C823_00056	2.67e-09	59.3	COG0069@1|root,COG0069@2|Bacteria,1TPVM@1239|Firmicutes,2487M@186801|Clostridia,25VQC@186806|Eubacteriaceae	186801|Clostridia	E	Conserved region in glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Glu_synthase,Rubredoxin
NIGDIANH_01618	411469.EUBHAL_00100	0.0	1009.0	COG0457@1|root,COG0457@2|Bacteria,1TTVC@1239|Firmicutes,24ESN@186801|Clostridia,25W86@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4037,DUF4125,TPR_10,TPR_12,TPR_7,TPR_8
NIGDIANH_01619	411469.EUBHAL_00101	1.04e-218	602.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,25W3J@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
NIGDIANH_01620	411489.CLOL250_01550	0.000335	42.4	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,36FEF@31979|Clostridiaceae	186801|Clostridia	P	Zinc transporter	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NIGDIANH_01621	411469.EUBHAL_02663	5.05e-157	444.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,25VP7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NIGDIANH_01622	411469.EUBHAL_02664	3.6e-109	319.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,25VF2@186806|Eubacteriaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NIGDIANH_01623	411469.EUBHAL_02665	0.0	943.0	COG0351@1|root,COG0637@1|root,COG0351@2|Bacteria,COG0637@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,25VDZ@186806|Eubacteriaceae	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NIGDIANH_01624	1232452.BAIB02000006_gene1437	9.13e-84	253.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NIGDIANH_01625	585394.RHOM_07120	1.57e-163	464.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NIGDIANH_01626	1235790.C805_01979	2.9e-62	207.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,25WMI@186806|Eubacteriaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
NIGDIANH_01627	411462.DORLON_02684	0.0	996.0	COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,247ZG@186801|Clostridia	186801|Clostridia	I	Belongs to the 3-oxoacid CoA-transferase family	-	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
NIGDIANH_01628	411469.EUBHAL_01880	4.51e-220	608.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24EXD@186801|Clostridia,25VMS@186806|Eubacteriaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
NIGDIANH_01629	411469.EUBHAL_01878	0.0	885.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,25V2R@186806|Eubacteriaceae	186801|Clostridia	T	Carbon starvation protein	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
NIGDIANH_01630	411469.EUBHAL_01876	1.01e-91	271.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia,25XNY@186806|Eubacteriaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NIGDIANH_01631	411469.EUBHAL_01728	4.42e-133	389.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia,25WKX@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NIGDIANH_01633	411469.EUBHAL_00918	1.21e-61	196.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,25V9W@186806|Eubacteriaceae	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NIGDIANH_01634	411469.EUBHAL_00917	7.28e-242	676.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,25X67@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01635	411469.EUBHAL_00916	3.63e-116	333.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,25W7A@186806|Eubacteriaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NIGDIANH_01637	585394.RHOM_02045	8.23e-87	264.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
NIGDIANH_01638	585394.RHOM_02045	5.53e-107	316.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
NIGDIANH_01640	585394.RHOM_02040	8.67e-09	52.8	2DN55@1|root,32VJQ@2|Bacteria,1VAWK@1239|Firmicutes,24NK4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01641	585394.RHOM_02035	2.67e-91	268.0	COG1396@1|root,COG1396@2|Bacteria,1V0KN@1239|Firmicutes,24FXG@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NIGDIANH_01642	585394.RHOM_02030	5.74e-87	265.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase,zinc_ribbon_2
NIGDIANH_01643	585394.RHOM_02030	1.66e-134	387.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase,zinc_ribbon_2
NIGDIANH_01644	411469.EUBHAL_01483	6.72e-42	137.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,25XIW@186806|Eubacteriaceae	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
NIGDIANH_01645	411469.EUBHAL_01482	9.78e-136	385.0	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia,25ZHS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_01646	478749.BRYFOR_08060	6.07e-24	97.4	2AYII@1|root,31QNA@2|Bacteria,1V7XG@1239|Firmicutes,25DCU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
NIGDIANH_01647	478749.BRYFOR_08061	6.45e-65	206.0	COG1309@1|root,COG1309@2|Bacteria,1VIW0@1239|Firmicutes,24TW4@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_01648	411469.EUBHAL_01479	2.25e-137	390.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,25W14@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
NIGDIANH_01649	411469.EUBHAL_01478	1.26e-113	328.0	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	mtrR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_01650	411469.EUBHAL_00046	1.69e-129	367.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,25W9H@186806|Eubacteriaceae	186801|Clostridia	M	Acetyltransferase (GNAT) family	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NIGDIANH_01651	1410632.JHWW01000005_gene733	5.64e-75	230.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,27MZJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NIGDIANH_01653	411469.EUBHAL_00819	0.0	875.0	COG1874@1|root,COG1874@2|Bacteria,1V23M@1239|Firmicutes,24GDA@186801|Clostridia	2|Bacteria	G	Beta-galactosidase	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Cellulase,DUF4832,GHL6,Glyco_hydro_42,Glyco_hydro_42M
NIGDIANH_01654	411469.EUBHAL_00821	0.0	929.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NIGDIANH_01655	411469.EUBHAL_00275	0.0	1446.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,25UVR@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NIGDIANH_01656	411469.EUBHAL_00276	0.0	1012.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,25V9Y@186806|Eubacteriaceae	186801|Clostridia	E	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NIGDIANH_01657	411469.EUBHAL_01526	1.13e-138	400.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,25V6G@186806|Eubacteriaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NIGDIANH_01658	411469.EUBHAL_01527	5.16e-248	680.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,25V0I@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NIGDIANH_01659	411469.EUBHAL_01528	6.64e-87	256.0	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,25XN3@186806|Eubacteriaceae	186801|Clostridia	S	NusG domain II	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
NIGDIANH_01660	411469.EUBHAL_01529	2.09e-303	828.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25VI9@186806|Eubacteriaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
NIGDIANH_01663	411461.DORFOR_01036	1.97e-37	129.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,27VHA@189330|Dorea	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
NIGDIANH_01665	411469.EUBHAL_02502	4e-128	363.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,25Z5M@186806|Eubacteriaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
NIGDIANH_01667	411469.EUBHAL_02503	4.14e-232	640.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
NIGDIANH_01668	411469.EUBHAL_01174	2.63e-292	797.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,25VQ3@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_01669	411469.EUBHAL_01175	0.0	1124.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,25UTE@186806|Eubacteriaceae	186801|Clostridia	IQ	AMP-binding enzyme C-terminal domain	lcfB	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
NIGDIANH_01670	411469.EUBHAL_01209	1.7e-271	748.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NIGDIANH_01671	411469.EUBHAL_01210	0.0	1141.0	COG0546@1|root,COG0673@1|root,COG0546@2|Bacteria,COG0673@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,25WHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NIGDIANH_01672	411469.EUBHAL_02015	2.88e-167	468.0	COG0760@1|root,COG0760@2|Bacteria,1V5Q2@1239|Firmicutes,248JQ@186801|Clostridia,25WK2@186806|Eubacteriaceae	186801|Clostridia	O	PPIC-type PPIASE domain	prsA2	-	5.2.1.8	ko:K03769,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
NIGDIANH_01673	411469.EUBHAL_02014	0.0	1108.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,25UZH@186806|Eubacteriaceae	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NIGDIANH_01674	411469.EUBHAL_00034	2.48e-126	359.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,25W8E@186806|Eubacteriaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NIGDIANH_01675	411469.EUBHAL_00035	2.85e-154	434.0	COG3201@1|root,COG3201@2|Bacteria,1V21G@1239|Firmicutes,24CVF@186801|Clostridia	186801|Clostridia	H	nicotinamide mononucleotide transporter	pnuC	-	-	-	-	-	-	-	-	-	-	-	NMN_transporter
NIGDIANH_01676	411469.EUBHAL_00370	1.61e-115	331.0	COG3760@1|root,COG3760@2|Bacteria,1V29H@1239|Firmicutes,25D4W@186801|Clostridia,25XJ9@186806|Eubacteriaceae	186801|Clostridia	S	YbaK proline--tRNA ligase associated domain protein	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NIGDIANH_01677	411469.EUBHAL_00369	1.3e-282	773.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,25W84@186806|Eubacteriaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NIGDIANH_01678	411459.RUMOBE_00751	8.36e-108	314.0	COG4123@1|root,COG4123@2|Bacteria,1UK35@1239|Firmicutes,25FHR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
NIGDIANH_01679	411462.DORLON_02750	0.0	869.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,27VAE@189330|Dorea	186801|Clostridia	L	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
NIGDIANH_01680	1280698.AUJS01000028_gene2272	1.67e-156	442.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia,27XE1@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4130	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
NIGDIANH_01681	411469.EUBHAL_01319	9.07e-143	403.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,25WR0@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NIGDIANH_01682	411469.EUBHAL_01318	0.0	1678.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,25UTU@186806|Eubacteriaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NIGDIANH_01688	1297617.JPJD01000058_gene1031	1.74e-105	308.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,268HG@186813|unclassified Clostridiales	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NIGDIANH_01689	411469.EUBHAL_00212	4.85e-278	761.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,25VTU@186806|Eubacteriaceae	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
NIGDIANH_01690	411469.EUBHAL_00213	3.67e-65	198.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,25WX1@186806|Eubacteriaceae	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NIGDIANH_01691	411469.EUBHAL_00214	3.39e-28	103.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,24R3H@186801|Clostridia,25XCB@186806|Eubacteriaceae	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
NIGDIANH_01692	411469.EUBHAL_00215	6.15e-62	189.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,25WK4@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NIGDIANH_01693	411461.DORFOR_01852	2.47e-69	215.0	COG0619@1|root,COG0619@2|Bacteria,1UYQQ@1239|Firmicutes	1239|Firmicutes	P	cobalt transport	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NIGDIANH_01694	411461.DORFOR_01853	2.2e-49	164.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02006,ko:K16786,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NIGDIANH_01695	411461.DORFOR_01853	1.05e-33	122.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	ko:K02006,ko:K16786,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NIGDIANH_01696	411461.DORFOR_01854	7.2e-159	447.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,27V52@189330|Dorea	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NIGDIANH_01697	411461.DORFOR_01855	2.6e-54	170.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,27VT3@189330|Dorea	186801|Clostridia	K	Stage III sporulation protein D	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NIGDIANH_01698	411461.DORFOR_01856	1.64e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1VM6R@1239|Firmicutes,24S0H@186801|Clostridia,27VWI@189330|Dorea	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NIGDIANH_01699	411469.EUBHAL_01891	5.94e-154	432.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,25W6X@186806|Eubacteriaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NIGDIANH_01700	411469.EUBHAL_01890	0.0	1177.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,25ZJZ@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C,HATPase_c,HisKA,PilJ,Response_reg,SBP_bac_3
NIGDIANH_01701	411469.EUBHAL_01889	8.34e-46	158.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,25V9H@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NIGDIANH_01702	411469.EUBHAL_01207	6.08e-153	430.0	COG0791@1|root,COG0791@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia,25W7X@186806|Eubacteriaceae	186801|Clostridia	MT	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
NIGDIANH_01703	411469.EUBHAL_01206	7.52e-246	678.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,25V4B@186806|Eubacteriaceae	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NIGDIANH_01704	411469.EUBHAL_01205	8.63e-221	616.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,25W62@186806|Eubacteriaceae	186801|Clostridia	S	5-bromo-4-chloroindolyl phosphate hydrolysis protein	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NIGDIANH_01705	411469.EUBHAL_00818	0.0	1201.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,25ZJY@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
NIGDIANH_01706	411469.EUBHAL_00817	1.27e-221	610.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,25VBR@186806|Eubacteriaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NIGDIANH_01708	411469.EUBHAL_00944	0.0	955.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,25VMR@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13,2.3.3.14	ko:K01649,ko:K02594	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R00271,R01213	RC00004,RC00067,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NIGDIANH_01709	411469.EUBHAL_00941	0.0	885.0	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria,1UK6Z@1239|Firmicutes,25FNP@186801|Clostridia,25WH7@186806|Eubacteriaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NIGDIANH_01710	411469.EUBHAL_00169	3.52e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,25WVQ@186806|Eubacteriaceae	186801|Clostridia	K	Iron dependent repressor DNA binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NIGDIANH_01711	411469.EUBHAL_00170	0.0	1075.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,25V5W@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NIGDIANH_01712	411469.EUBHAL_01078	5.58e-197	548.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,25W6J@186806|Eubacteriaceae	186801|Clostridia	P	permease protein	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NIGDIANH_01713	411469.EUBHAL_01077	6.29e-189	526.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,25VBN@186806|Eubacteriaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NIGDIANH_01714	411469.EUBHAL_01076	4.78e-193	537.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,25W11@186806|Eubacteriaceae	186801|Clostridia	P	COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NIGDIANH_01715	411469.EUBHAL_00193	1.2e-145	411.0	COG1309@1|root,COG1309@2|Bacteria,1V27T@1239|Firmicutes,24G6P@186801|Clostridia,25XV2@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_01716	411469.EUBHAL_00194	4.97e-227	625.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,25WK8@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NIGDIANH_01717	411469.EUBHAL_00195	0.0	1063.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,25WXC@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
NIGDIANH_01718	483218.BACPEC_02687	6.41e-35	120.0	2DN0F@1|root,32UQJ@2|Bacteria,1VBR6@1239|Firmicutes,24NWZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NIGDIANH_01719	411469.EUBHAL_01599	5.86e-168	469.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,25W6G@186806|Eubacteriaceae	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NIGDIANH_01720	1280698.AUJS01000041_gene2527	5.11e-186	523.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NIGDIANH_01721	411469.EUBHAL_01598	4.75e-158	444.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,25WEN@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NIGDIANH_01722	1121115.AXVN01000065_gene686	4.17e-46	152.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
NIGDIANH_01723	411469.EUBHAL_01857	9.18e-317	864.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,25VMW@186806|Eubacteriaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NIGDIANH_01724	411469.EUBHAL_01855	1e-76	234.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,25VC6@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NIGDIANH_01725	411469.EUBHAL_01855	1.69e-104	307.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,25VC6@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NIGDIANH_01726	411469.EUBHAL_01854	1.54e-156	440.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,25VTY@186806|Eubacteriaceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NIGDIANH_01727	411469.EUBHAL_01023	7.24e-212	586.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,25VWY@186806|Eubacteriaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
NIGDIANH_01728	411469.EUBHAL_01022	1.27e-207	582.0	2DISP@1|root,3042D@2|Bacteria,1VKA2@1239|Firmicutes,24W6M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01729	411469.EUBHAL_00178	2e-296	811.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,25VQZ@186806|Eubacteriaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
NIGDIANH_01730	411469.EUBHAL_00177	0.0	1054.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,25UZK@186806|Eubacteriaceae	186801|Clostridia	O	Peptidase, U32 family	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NIGDIANH_01731	411469.EUBHAL_01881	0.0	1212.0	COG2918@1|root,COG3572@1|root,COG2918@2|Bacteria,COG3572@2|Bacteria,1TPGX@1239|Firmicutes,25ER3@186801|Clostridia,25VNV@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the glutamate--cysteine ligase type 1 family	gshF	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase,RimK
NIGDIANH_01732	411469.EUBHAL_01882	1.92e-178	498.0	COG0121@1|root,COG0121@2|Bacteria,1V636@1239|Firmicutes,24IUW@186801|Clostridia,25WI8@186806|Eubacteriaceae	186801|Clostridia	S	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_4
NIGDIANH_01733	411469.EUBHAL_01883	2.69e-178	496.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,25VTH@186806|Eubacteriaceae	186801|Clostridia	H	ThiF family	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NIGDIANH_01734	411469.EUBHAL_01795	3.73e-98	290.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,25X0W@186806|Eubacteriaceae	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_01735	411469.EUBHAL_01796	2.7e-164	459.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,25V4X@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NIGDIANH_01736	411469.EUBHAL_01443	6.06e-58	184.0	COG0120@1|root,COG0120@2|Bacteria,1V22S@1239|Firmicutes,25CNZ@186801|Clostridia	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
NIGDIANH_01737	411469.EUBHAL_01445	3.19e-238	654.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,25VV9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NIGDIANH_01738	1232447.BAHW02000027_gene1797	4.72e-22	92.4	COG0561@1|root,COG0561@2|Bacteria,1TS38@1239|Firmicutes,25BK5@186801|Clostridia	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NIGDIANH_01739	411469.EUBHAL_01449	1.41e-305	835.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_01740	411469.EUBHAL_02980	9.74e-164	458.0	COG2323@1|root,COG2323@2|Bacteria,1TRWQ@1239|Firmicutes,24CFP@186801|Clostridia,25ZH3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
NIGDIANH_01741	411469.EUBHAL_02979	5.27e-117	335.0	COG1014@1|root,COG1014@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia,25V6V@186806|Eubacteriaceae	186801|Clostridia	C	2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family	porC	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
NIGDIANH_01742	411469.EUBHAL_02978	2.96e-88	258.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,25VQ8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
NIGDIANH_01743	411469.EUBHAL_02977	1.49e-136	385.0	COG1013@1|root,COG1013@2|Bacteria,1TPF0@1239|Firmicutes,24BE5@186801|Clostridia,25VQ8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	porB	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
NIGDIANH_01744	411469.EUBHAL_02976	5.79e-92	270.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,25WJB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NIGDIANH_01745	411469.EUBHAL_01759	4.13e-294	803.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,25VPG@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NIGDIANH_01747	411469.EUBHAL_03238	4.62e-135	382.0	COG4186@1|root,COG4186@2|Bacteria,1V40P@1239|Firmicutes,24D6T@186801|Clostridia,25WCV@186806|Eubacteriaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
NIGDIANH_01748	411469.EUBHAL_03239	1.2e-155	436.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,25WSY@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
NIGDIANH_01749	411469.EUBHAL_03240	0.0	895.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
NIGDIANH_01750	411469.EUBHAL_02713	3.75e-241	691.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25UYI@186806|Eubacteriaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NIGDIANH_01751	411469.EUBHAL_02713	8.28e-137	415.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,25UYI@186806|Eubacteriaceae	186801|Clostridia	D	FtsK SpoIIIE family protein	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NIGDIANH_01752	411469.EUBHAL_02714	5.62e-200	554.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,25V5T@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NIGDIANH_01753	411469.EUBHAL_01697	9.76e-298	811.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia,25YHB@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0160)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
NIGDIANH_01754	411469.EUBHAL_01698	2.23e-235	648.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,25V9E@186806|Eubacteriaceae	186801|Clostridia	P	cobalamin biosynthesis protein	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
NIGDIANH_01755	411469.EUBHAL_01699	1.39e-192	535.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia	186801|Clostridia	P	cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NIGDIANH_01756	1121115.AXVN01000024_gene304	9.94e-143	404.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3Y0H7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NIGDIANH_01757	1121115.AXVN01000024_gene303	5.88e-163	456.0	COG5036@1|root,COG5036@2|Bacteria,1V27Y@1239|Firmicutes,25D4R@186801|Clostridia,3Y0DX@572511|Blautia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NIGDIANH_01758	1121115.AXVN01000024_gene302	2.7e-205	568.0	2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,24C2H@186801|Clostridia,3Y1UZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01759	411469.EUBHAL_02382	2.76e-220	608.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,25V83@186806|Eubacteriaceae	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NIGDIANH_01760	411469.EUBHAL_02381	0.0	1104.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NIGDIANH_01761	411469.EUBHAL_02380	1.59e-61	206.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,25V2F@186806|Eubacteriaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
NIGDIANH_01762	478749.BRYFOR_08968	3.39e-167	474.0	COG4823@1|root,COG4823@2|Bacteria,1UZPR@1239|Firmicutes,24B3R@186801|Clostridia	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NIGDIANH_01764	585394.RHOM_04355	1.8e-173	486.0	COG3393@1|root,COG3393@2|Bacteria,1TRN7@1239|Firmicutes,24A2B@186801|Clostridia	186801|Clostridia	S	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NIGDIANH_01765	411469.EUBHAL_03066	1.3e-281	772.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,25VNE@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NIGDIANH_01766	411469.EUBHAL_03065	0.0	928.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,25WXS@186806|Eubacteriaceae	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
NIGDIANH_01767	1123313.ATUT01000032_gene1893	2.88e-148	426.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ1Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
NIGDIANH_01769	411469.EUBHAL_02056	8.93e-153	430.0	2AE9J@1|root,3143R@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01770	411469.EUBHAL_02057	1.3e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,25VM1@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01771	411469.EUBHAL_02058	2.78e-308	842.0	COG5002@1|root,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,25WC3@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NIGDIANH_01772	411469.EUBHAL_03257	1.68e-41	145.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,25WHT@186806|Eubacteriaceae	186801|Clostridia	M	Peptidase, M23 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NIGDIANH_01774	411469.EUBHAL_03255	6.86e-60	184.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,25XBE@186806|Eubacteriaceae	186801|Clostridia	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
NIGDIANH_01775	411469.EUBHAL_03254	6.64e-154	432.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,25W4H@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
NIGDIANH_01776	411469.EUBHAL_03252	1.03e-202	560.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,25VVY@186806|Eubacteriaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
NIGDIANH_01777	411461.DORFOR_00034	1.01e-46	156.0	2E1TI@1|root,32X3C@2|Bacteria,1VJS0@1239|Firmicutes,24T9T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01778	1232453.BAIF02000057_gene1120	4.85e-113	332.0	COG2337@1|root,COG2337@2|Bacteria,1VBM6@1239|Firmicutes,24P9S@186801|Clostridia	186801|Clostridia	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NIGDIANH_01779	411461.DORFOR_00037	1.61e-245	685.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,24CXI@186801|Clostridia,27WA6@189330|Dorea	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NIGDIANH_01780	411462.DORLON_01191	1.13e-72	229.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01782	411469.EUBHAL_01860	3.08e-128	365.0	COG1961@1|root,COG1961@2|Bacteria,1V51N@1239|Firmicutes,24D8I@186801|Clostridia,25XGG@186806|Eubacteriaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_7,Resolvase
NIGDIANH_01783	411461.DORFOR_01507	7.03e-44	142.0	2CCVX@1|root,33G73@2|Bacteria,1VN7A@1239|Firmicutes,24W0K@186801|Clostridia,27X5F@189330|Dorea	186801|Clostridia	S	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
NIGDIANH_01784	411461.DORFOR_01506	1.9e-194	540.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,27W51@189330|Dorea	186801|Clostridia	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NIGDIANH_01785	411461.DORFOR_01505	1.62e-242	669.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,27VQT@189330|Dorea	186801|Clostridia	H	FAD binding domain	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NIGDIANH_01786	411469.EUBHAL_00972	0.0	1308.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NIGDIANH_01787	471875.RUMLAC_00564	0.0	873.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NIGDIANH_01788	471875.RUMLAC_00562	1.34e-91	272.0	COG1309@1|root,COG1309@2|Bacteria,1V44I@1239|Firmicutes,24I73@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_01789	478749.BRYFOR_07602	3.01e-61	191.0	COG1598@1|root,COG1598@2|Bacteria,1V1WA@1239|Firmicutes,25D5F@186801|Clostridia	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
NIGDIANH_01790	397287.C807_02609	2.92e-26	97.4	COG1724@1|root,COG1724@2|Bacteria,1VGR5@1239|Firmicutes,24QWD@186801|Clostridia,27PY5@186928|unclassified Lachnospiraceae	186801|Clostridia	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
NIGDIANH_01792	411469.EUBHAL_03187	5.18e-166	467.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,25XE5@186806|Eubacteriaceae	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NIGDIANH_01793	411469.EUBHAL_03186	2.58e-65	199.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25WU9@186806|Eubacteriaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NIGDIANH_01794	411469.EUBHAL_02243	2.26e-22	88.6	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24RPR@186801|Clostridia,25XFV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01795	411469.EUBHAL_02242	0.0	1425.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,25VCX@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NIGDIANH_01796	742765.HMPREF9457_02572	1.02e-126	369.0	COG0715@1|root,COG0715@2|Bacteria,1V0DX@1239|Firmicutes,257M1@186801|Clostridia,27WFM@189330|Dorea	186801|Clostridia	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
NIGDIANH_01797	742765.HMPREF9457_02573	3.39e-181	504.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,27WC2@189330|Dorea	186801|Clostridia	P	ATPases associated with a variety of cellular activities	tauB	-	3.6.3.36	ko:K02049,ko:K10831	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
NIGDIANH_01798	742765.HMPREF9457_02574	1.18e-296	807.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,27V4M@189330|Dorea	186801|Clostridia	E	Aminotransferase class I and II	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NIGDIANH_01799	411469.EUBHAL_03212	3.42e-97	282.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,25WZC@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NIGDIANH_01800	411469.EUBHAL_03213	9.56e-211	582.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NIGDIANH_01801	411469.EUBHAL_03214	9.43e-139	393.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,25WRC@186806|Eubacteriaceae	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NIGDIANH_01802	411469.EUBHAL_03215	4.44e-123	352.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,25WPT@186806|Eubacteriaceae	186801|Clostridia	P	CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NIGDIANH_01804	411462.DORLON_00330	8.39e-115	335.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,27VGX@189330|Dorea	186801|Clostridia	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE_1	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NIGDIANH_01805	397287.C807_01420	1.32e-34	131.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,27KBB@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Domain of unknown function (DUF4118)	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
NIGDIANH_01806	1298920.KI911353_gene5077	7.1e-49	161.0	COG1959@1|root,COG1959@2|Bacteria,1V9YG@1239|Firmicutes,24JFX@186801|Clostridia,220EE@1506553|Lachnoclostridium	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NIGDIANH_01807	411462.DORLON_01183	5.79e-44	145.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,27VRK@189330|Dorea	186801|Clostridia	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NIGDIANH_01808	1410633.JHWR01000008_gene1692	1.3e-19	88.2	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,27JJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NIGDIANH_01810	1235800.C819_00236	1.25e-191	541.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,27JIF@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NIGDIANH_01813	411467.BACCAP_00421	1.74e-10	62.4	2C2T8@1|root,32RB0@2|Bacteria,1V8YX@1239|Firmicutes,24M80@186801|Clostridia,26B0Z@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01820	1280663.ATVR01000009_gene2143	1.8e-14	74.3	2CHE7@1|root,33YAK@2|Bacteria,1VVZG@1239|Firmicutes,250V4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01822	411469.EUBHAL_01845	7.09e-206	573.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,25VFR@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NIGDIANH_01823	411469.EUBHAL_01846	4.54e-242	666.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,25VB3@186806|Eubacteriaceae	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NIGDIANH_01824	411469.EUBHAL_01847	1.21e-29	112.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,25W35@186806|Eubacteriaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NIGDIANH_01825	411469.EUBHAL_01847	2.34e-38	132.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,25W35@186806|Eubacteriaceae	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NIGDIANH_01826	411469.EUBHAL_00263	0.0	916.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NIGDIANH_01827	411469.EUBHAL_00262	5.73e-202	558.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,25US8@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	nfnA	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NIGDIANH_01828	411469.EUBHAL_00261	1.33e-164	473.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,25V0C@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NIGDIANH_01829	994573.T472_0205070	1.42e-52	197.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,248C6@186801|Clostridia,36GGX@31979|Clostridiaceae	186801|Clostridia	M	TIGRFAM RHS repeat-associated core	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
NIGDIANH_01831	1216932.CM240_0570	9.31e-72	227.0	2CJFU@1|root,30ZR8@2|Bacteria,1V5NS@1239|Firmicutes,24JAT@186801|Clostridia,36RH3@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01832	411463.EUBVEN_02104	1.37e-182	523.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,25VTI@186806|Eubacteriaceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NIGDIANH_01833	97139.C824_03594	7.52e-157	448.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia,36U0E@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01834	1280698.AUJS01000004_gene2882	7.97e-74	224.0	2BFEN@1|root,32IZG@2|Bacteria,1UQ3H@1239|Firmicutes,257RM@186801|Clostridia,27X8E@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NIGDIANH_01835	411468.CLOSCI_00122	1.46e-146	448.0	COG1621@1|root,COG3408@1|root,COG1621@2|Bacteria,COG3408@2|Bacteria,1US47@1239|Firmicutes,24YE5@186801|Clostridia	186801|Clostridia	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01836	693746.OBV_37290	3.61e-77	246.0	COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,25KRI@186801|Clostridia,2N6I3@216572|Oscillospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1
NIGDIANH_01837	411459.RUMOBE_03913	2.7e-12	65.9	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3XZ5Z@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NIGDIANH_01838	411469.EUBHAL_03019	0.0	960.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,25VJ7@186806|Eubacteriaceae	186801|Clostridia	H	Acetolactate synthase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NIGDIANH_01839	411469.EUBHAL_03020	2.14e-278	761.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,25VFK@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NIGDIANH_01840	411469.EUBHAL_01261	5.44e-132	375.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,25WSX@186806|Eubacteriaceae	186801|Clostridia	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
NIGDIANH_01841	411469.EUBHAL_01260	1.36e-266	731.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,25UYG@186806|Eubacteriaceae	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NIGDIANH_01842	411469.EUBHAL_01259	1.73e-122	348.0	COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,24BYP@186801|Clostridia,25VJQ@186806|Eubacteriaceae	186801|Clostridia	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
NIGDIANH_01844	411469.EUBHAL_02947	7.43e-113	326.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,25WBF@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NIGDIANH_01845	411469.EUBHAL_02948	1.69e-41	136.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,25XFP@186806|Eubacteriaceae	186801|Clostridia	S	NOG16862 non supervised orthologous group	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
NIGDIANH_01846	411469.EUBHAL_02949	3.55e-296	810.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,25VD0@186806|Eubacteriaceae	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NIGDIANH_01847	411469.EUBHAL_02330	7.72e-206	570.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NIGDIANH_01848	411469.EUBHAL_02329	7.21e-203	562.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
NIGDIANH_01849	742765.HMPREF9457_03792	4.58e-93	277.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,27WP9@189330|Dorea	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NIGDIANH_01850	742765.HMPREF9457_03791	3.38e-302	821.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,27WFI@189330|Dorea	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
NIGDIANH_01851	397291.C804_01804	8.78e-94	296.0	COG0840@1|root,COG0840@2|Bacteria,1V13D@1239|Firmicutes,24AVS@186801|Clostridia,27KTS@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
NIGDIANH_01852	1123309.AQYB01000030_gene1825	4.06e-190	545.0	2BVE2@1|root,32QTW@2|Bacteria,1VD6K@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01854	411461.DORFOR_00302	1.49e-251	691.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,27VBR@189330|Dorea	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
NIGDIANH_01855	411461.DORFOR_00303	5.12e-38	127.0	COG0425@1|root,COG0425@2|Bacteria,1VFJ3@1239|Firmicutes,24QUZ@186801|Clostridia,27VW7@189330|Dorea	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NIGDIANH_01856	411461.DORFOR_00304	1.96e-71	215.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,27VT5@189330|Dorea	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NIGDIANH_01857	411469.EUBHAL_00112	6.68e-164	457.0	COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,2497A@186801|Clostridia,25VE2@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
NIGDIANH_01858	411469.EUBHAL_00113	2.17e-134	381.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,25W67@186806|Eubacteriaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
NIGDIANH_01859	411469.EUBHAL_00114	5.49e-163	455.0	COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,2499R@186801|Clostridia,25W1R@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NIGDIANH_01860	411469.EUBHAL_00115	5.33e-100	290.0	COG0720@1|root,COG0720@2|Bacteria,1VAJX@1239|Firmicutes,24JS9@186801|Clostridia,25WPS@186806|Eubacteriaceae	186801|Clostridia	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
NIGDIANH_01861	411469.EUBHAL_00174	6.02e-151	426.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,25W9F@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NIGDIANH_01862	411469.EUBHAL_00175	9.8e-234	644.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,25VC7@186806|Eubacteriaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NIGDIANH_01863	411469.EUBHAL_00176	4.08e-83	246.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,25XHG@186806|Eubacteriaceae	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NIGDIANH_01864	411469.EUBHAL_01917	0.0	880.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,25VX9@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01865	411469.EUBHAL_01918	1.1e-162	455.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,25VJK@186806|Eubacteriaceae	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NIGDIANH_01866	411469.EUBHAL_01919	3.86e-105	305.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,25WZ4@186806|Eubacteriaceae	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NIGDIANH_01867	411469.EUBHAL_03100	9.28e-62	194.0	29XBC@1|root,30J12@2|Bacteria,1UGNA@1239|Firmicutes,24WPR@186801|Clostridia,25Z9G@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NIGDIANH_01868	411469.EUBHAL_03100	1.61e-86	259.0	29XBC@1|root,30J12@2|Bacteria,1UGNA@1239|Firmicutes,24WPR@186801|Clostridia,25Z9G@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NIGDIANH_01869	1304880.JAGB01000002_gene2395	1.34e-18	87.0	COG0745@1|root,COG0745@2|Bacteria,1TPF7@1239|Firmicutes,24916@186801|Clostridia	186801|Clostridia	KT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Spo0A_C
NIGDIANH_01870	411469.EUBHAL_00971	4.23e-269	759.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,25VNK@186806|Eubacteriaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NIGDIANH_01871	411469.EUBHAL_01981	0.0	985.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25VMN@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NIGDIANH_01872	411469.EUBHAL_01663	8.98e-225	619.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1VFW6@1239|Firmicutes,24QTV@186801|Clostridia,25XEN@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,NTP_transf_3
NIGDIANH_01875	411469.EUBHAL_01373	1.69e-191	531.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,25VBB@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NIGDIANH_01876	411469.EUBHAL_01371	1.58e-212	588.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,25VH3@186806|Eubacteriaceae	186801|Clostridia	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NIGDIANH_01879	398720.MED217_12959	0.00062	44.3	COG1476@1|root,COG1476@2|Bacteria,4NVQ6@976|Bacteroidetes,1I51D@117743|Flavobacteriia	976|Bacteroidetes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NIGDIANH_01881	445974.CLORAM_02962	9.95e-46	159.0	2AHFH@1|root,317ST@2|Bacteria,1V7CC@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
NIGDIANH_01884	411461.DORFOR_02503	1.15e-216	598.0	COG3835@1|root,COG3835@2|Bacteria,1V0D7@1239|Firmicutes,247VQ@186801|Clostridia	186801|Clostridia	KT	COG COG3835 Sugar diacid utilization regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NIGDIANH_01885	742765.HMPREF9457_00533	4.83e-156	444.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27V29@189330|Dorea	186801|Clostridia	P	COG COG3839 ABC-type sugar transport systems, ATPase components	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NIGDIANH_01886	411461.DORFOR_02502	1.19e-94	285.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27V29@189330|Dorea	186801|Clostridia	P	COG COG3839 ABC-type sugar transport systems, ATPase components	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NIGDIANH_01887	411469.EUBHAL_00289	2.57e-170	476.0	COG1349@1|root,COG1349@2|Bacteria,1TNYH@1239|Firmicutes,24BT5@186801|Clostridia,25ZNQ@186806|Eubacteriaceae	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NIGDIANH_01888	411469.EUBHAL_00206	5.68e-21	86.3	COG1672@1|root,COG1672@2|Bacteria,1W4XZ@1239|Firmicutes,2551K@186801|Clostridia,25Z7T@186806|Eubacteriaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like
NIGDIANH_01889	411469.EUBHAL_01509	4.11e-234	669.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25NQ9@186801|Clostridia,25UTS@186806|Eubacteriaceae	186801|Clostridia	S	Peptidase M16 inactive domain	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
NIGDIANH_01890	411469.EUBHAL_01510	6.74e-213	588.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,25VJE@186806|Eubacteriaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NIGDIANH_01891	411469.EUBHAL_01511	1.9e-175	489.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,25WGP@186806|Eubacteriaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NIGDIANH_01892	411469.EUBHAL_03137	0.0	1530.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NIGDIANH_01893	411469.EUBHAL_00197	3.17e-150	422.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,25WUR@186806|Eubacteriaceae	186801|Clostridia	T	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
NIGDIANH_01894	411469.EUBHAL_00196	2.87e-256	706.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,25XK7@186806|Eubacteriaceae	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01895	411469.EUBHAL_02031	2.04e-61	210.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,1VMHH@1239|Firmicutes,25KIJ@186801|Clostridia,25YV0@186806|Eubacteriaceae	186801|Clostridia	D	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01896	411469.EUBHAL_02031	6.17e-46	164.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria,1VMHH@1239|Firmicutes,25KIJ@186801|Clostridia,25YV0@186806|Eubacteriaceae	186801|Clostridia	D	Immunoglobulin	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01897	411469.EUBHAL_02032	4.77e-155	436.0	2DMUC@1|root,32TQR@2|Bacteria,1V9Y3@1239|Firmicutes,24QZE@186801|Clostridia,25X8E@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
NIGDIANH_01898	411469.EUBHAL_02033	8.41e-46	147.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,25X15@186806|Eubacteriaceae	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NIGDIANH_01899	411469.EUBHAL_02733	8.04e-72	216.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,25WAZ@186806|Eubacteriaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NIGDIANH_01900	411469.EUBHAL_02732	1.19e-33	116.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,25X8W@186806|Eubacteriaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NIGDIANH_01901	411469.EUBHAL_02731	4.22e-105	304.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,25WSI@186806|Eubacteriaceae	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NIGDIANH_01902	411469.EUBHAL_02730	7.41e-117	333.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,25W7R@186806|Eubacteriaceae	186801|Clostridia	F	Psort location Cytoplasmic, score	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NIGDIANH_01903	411469.EUBHAL_01848	3.15e-84	265.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NIGDIANH_01904	411469.EUBHAL_01849	2.84e-214	600.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,25UX4@186806|Eubacteriaceae	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NIGDIANH_01905	411469.EUBHAL_01850	4.13e-229	631.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,25UY1@186806|Eubacteriaceae	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NIGDIANH_01906	411469.EUBHAL_02894	2.31e-180	502.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,25WAS@186806|Eubacteriaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NIGDIANH_01907	411469.EUBHAL_02895	6.46e-109	313.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,25WB9@186806|Eubacteriaceae	186801|Clostridia	C	[2Fe-2S] binding domain	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NIGDIANH_01908	411461.DORFOR_00885	8.39e-196	543.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,27VG6@189330|Dorea	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NIGDIANH_01909	411461.DORFOR_00886	2.4e-258	710.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,27VG4@189330|Dorea	186801|Clostridia	D	Cell cycle protein	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NIGDIANH_01911	411469.EUBHAL_02851	1.99e-301	821.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,25URF@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NIGDIANH_01912	903814.ELI_3903	8.62e-72	225.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,24F29@186801|Clostridia,25WVP@186806|Eubacteriaceae	186801|Clostridia	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
NIGDIANH_01913	931626.Awo_c30600	2.97e-118	350.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,25WAW@186806|Eubacteriaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NIGDIANH_01914	411459.RUMOBE_02354	7.08e-113	327.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,25B1X@186801|Clostridia,3XZYD@572511|Blautia	186801|Clostridia	T	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
NIGDIANH_01915	411459.RUMOBE_02355	4.5e-126	373.0	COG4585@1|root,COG4585@2|Bacteria,1UUZ9@1239|Firmicutes,248T2@186801|Clostridia,3Y033@572511|Blautia	186801|Clostridia	T	COG COG4585 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
NIGDIANH_01916	903814.ELI_0048	5.48e-155	449.0	COG1070@1|root,COG1070@2|Bacteria,1U0HE@1239|Firmicutes,24EBF@186801|Clostridia,25UW2@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NIGDIANH_01917	411469.EUBHAL_00230	4.33e-153	430.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,25W3V@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
NIGDIANH_01918	903814.ELI_1422	9.71e-84	262.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24EXD@186801|Clostridia,25VMS@186806|Eubacteriaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	Sugar-bind
NIGDIANH_01919	411469.EUBHAL_01307	3.41e-80	238.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,25WPN@186806|Eubacteriaceae	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NIGDIANH_01920	411469.EUBHAL_01306	0.0	1182.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,25V39@186806|Eubacteriaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NIGDIANH_01921	411461.DORFOR_00706	0.0	1182.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,27V33@189330|Dorea	186801|Clostridia	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
NIGDIANH_01922	411469.EUBHAL_02855	2.87e-218	602.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,25UVD@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NIGDIANH_01923	411469.EUBHAL_02854	2.78e-311	848.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,25UVC@186806|Eubacteriaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NIGDIANH_01924	411469.EUBHAL_01238	1.06e-61	198.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,25ZF8@186806|Eubacteriaceae	186801|Clostridia	S	CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NIGDIANH_01925	411469.EUBHAL_01454	0.0	905.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,25V3H@186806|Eubacteriaceae	186801|Clostridia	P	Potassium transporter peripheral membrane component	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NIGDIANH_01926	411469.EUBHAL_01453	1.94e-161	454.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,25VB0@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NIGDIANH_01927	411469.EUBHAL_01927	1.51e-111	338.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,25UV4@186806|Eubacteriaceae	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NIGDIANH_01928	411469.EUBHAL_01928	1.74e-185	516.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NIGDIANH_01929	411469.EUBHAL_01929	1.14e-120	345.0	COG2263@1|root,COG2263@2|Bacteria,1UK73@1239|Firmicutes,25FNT@186801|Clostridia,25ZK4@186806|Eubacteriaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,rRNA_methylase
NIGDIANH_01930	411490.ANACAC_02953	1.51e-230	641.0	COG0493@1|root,COG0493@2|Bacteria,1TR18@1239|Firmicutes,24A8Q@186801|Clostridia	186801|Clostridia	E	'oxidoreductase	-	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NIGDIANH_01931	411490.ANACAC_02952	1.35e-90	266.0	28NYX@1|root,2ZBVY@2|Bacteria,1V67E@1239|Firmicutes,24KRB@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1097
NIGDIANH_01932	1449050.JNLE01000003_gene3896	1.17e-11	70.9	COG5484@1|root,COG5484@2|Bacteria,1V6XI@1239|Firmicutes,24HPQ@186801|Clostridia,36JA4@31979|Clostridiaceae	186801|Clostridia	L	DNA packaging	-	-	-	-	-	-	-	-	-	-	-	-	Phage_terminase,Sigma70_r4_2,Terminase_5
NIGDIANH_01934	1313421.JHBV01000043_gene3075	5.92e-06	50.1	COG4974@1|root,COG4974@2|Bacteria,4NE0E@976|Bacteroidetes,1IP1B@117747|Sphingobacteriia	976|Bacteroidetes	L	Tyrosine recombinase XerC	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NIGDIANH_01935	411461.DORFOR_01744	1.49e-176	492.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,27VHH@189330|Dorea	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
NIGDIANH_01936	411461.DORFOR_01745	3.98e-205	569.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,27W2Y@189330|Dorea	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NIGDIANH_01937	411461.DORFOR_01746	3.35e-190	529.0	COG4636@1|root,COG4636@2|Bacteria,1V0MZ@1239|Firmicutes,25DP0@186801|Clostridia,27XBT@189330|Dorea	186801|Clostridia	K	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Uma2
NIGDIANH_01938	411469.EUBHAL_02759	2.07e-146	416.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,25VRZ@186806|Eubacteriaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NIGDIANH_01939	411469.EUBHAL_02758	2.93e-174	485.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia,25WSF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
NIGDIANH_01940	411469.EUBHAL_02757	2.61e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,25WVB@186806|Eubacteriaceae	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NIGDIANH_01941	411469.EUBHAL_02756	1.49e-53	167.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NIGDIANH_01942	411469.EUBHAL_02755	4.96e-57	178.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NIGDIANH_01943	411461.DORFOR_01500	7.01e-123	358.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,27VJV@189330|Dorea	186801|Clostridia	G	Glycerate kinase family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
NIGDIANH_01944	411461.DORFOR_01499	2.43e-80	238.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,27VRY@189330|Dorea	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NIGDIANH_01945	411461.DORFOR_01498	3.57e-65	197.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,24QHV@186801|Clostridia,27WXF@189330|Dorea	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
NIGDIANH_01946	411461.DORFOR_01497	1.43e-105	305.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,27W5E@189330|Dorea	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NIGDIANH_01947	411461.DORFOR_01496	2.08e-75	231.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,27VFM@189330|Dorea	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NIGDIANH_01948	411461.DORFOR_01496	5.95e-66	206.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,27VFM@189330|Dorea	186801|Clostridia	P	ZIP Zinc transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NIGDIANH_01949	411469.EUBHAL_01673	1.27e-170	477.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,25VA3@186806|Eubacteriaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NIGDIANH_01950	411469.EUBHAL_01674	3.95e-253	696.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,25URP@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NIGDIANH_01951	1293054.HSACCH_01054	1.71e-167	492.0	2906S@1|root,2ZMWJ@2|Bacteria,1W4MG@1239|Firmicutes,255KP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01952	411469.EUBHAL_02708	3.66e-117	354.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NIGDIANH_01953	411469.EUBHAL_02708	0.0	929.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,25V7M@186806|Eubacteriaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NIGDIANH_01954	411469.EUBHAL_02638	4.68e-196	543.0	COG5564@1|root,COG5564@2|Bacteria,1TS71@1239|Firmicutes,24AYD@186801|Clostridia,25VQT@186806|Eubacteriaceae	186801|Clostridia	S	Phosphoenolpyruvate hydrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	PEP_hydrolase
NIGDIANH_01955	411469.EUBHAL_02639	3.41e-287	786.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia,25W0H@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
NIGDIANH_01956	411469.EUBHAL_02640	1.35e-118	348.0	COG2207@1|root,COG5564@1|root,COG2207@2|Bacteria,COG5564@2|Bacteria,1U9WW@1239|Firmicutes,24CZJ@186801|Clostridia,25Y96@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PEP_hydrolase
NIGDIANH_01957	411469.EUBHAL_01167	1.17e-18	84.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,25UZ3@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
NIGDIANH_01958	411469.EUBHAL_01167	0.0	958.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,25UZ3@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
NIGDIANH_01959	411469.EUBHAL_01166	1.36e-66	202.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24S4A@186801|Clostridia	186801|Clostridia	S	Trp repressor protein	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NIGDIANH_01960	1298920.KI911353_gene2058	1.01e-21	85.5	2DU1T@1|root,33NJT@2|Bacteria,1VNPT@1239|Firmicutes,24W2B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01961	1226325.HMPREF1548_05267	8.08e-252	696.0	COG3547@1|root,COG3547@2|Bacteria,1TRSB@1239|Firmicutes,249AC@186801|Clostridia,36GX8@31979|Clostridiaceae	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NIGDIANH_01962	411469.EUBHAL_01270	4.23e-293	799.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25X6Z@186806|Eubacteriaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
NIGDIANH_01963	411469.EUBHAL_01269	1.44e-227	627.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,25VRJ@186806|Eubacteriaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NIGDIANH_01964	411469.EUBHAL_00658	1.69e-252	695.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,25VHJ@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NIGDIANH_01965	411469.EUBHAL_00659	8.22e-217	598.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,25VWS@186806|Eubacteriaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NIGDIANH_01966	411469.EUBHAL_00660	1.58e-70	212.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,25Z86@186806|Eubacteriaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NIGDIANH_01967	411469.EUBHAL_01520	7.31e-165	472.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,25VUP@186806|Eubacteriaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NIGDIANH_01968	1280698.AUJS01000030_gene1909	2.64e-181	508.0	2D2TB@1|root,32TDJ@2|Bacteria,1VB0C@1239|Firmicutes,24M7R@186801|Clostridia,27VQE@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
NIGDIANH_01969	1280698.AUJS01000030_gene1908	5.19e-98	286.0	2DVQP@1|root,33WTN@2|Bacteria,1VVAJ@1239|Firmicutes,25DDH@186801|Clostridia,27XD8@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01970	1280698.AUJS01000030_gene1907	5.69e-53	167.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,27VUV@189330|Dorea	186801|Clostridia	S	TSCPD domain	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NIGDIANH_01971	411469.EUBHAL_01450	1.43e-307	838.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,25URS@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NIGDIANH_01972	411469.EUBHAL_01452	3.96e-97	283.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,25WX5@186806|Eubacteriaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
NIGDIANH_01973	1121115.AXVN01000117_gene3359	1.4e-86	255.0	COG1848@1|root,COG1848@2|Bacteria,1VFQN@1239|Firmicutes,24NXI@186801|Clostridia	186801|Clostridia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN,PIN_3
NIGDIANH_01975	1121115.AXVN01000117_gene3357	5.92e-97	281.0	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01977	1121115.AXVN01000117_gene3355	8.76e-126	357.0	2EWQA@1|root,33Q24@2|Bacteria,1VRMX@1239|Firmicutes,24NS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01978	411469.EUBHAL_01807	5.87e-96	296.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,25V5G@186806|Eubacteriaceae	186801|Clostridia	T	K07718 two-component system, sensor histidine kinase YesM	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NIGDIANH_01979	411469.EUBHAL_01813	3.8e-226	624.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia,25W6Y@186806|Eubacteriaceae	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NIGDIANH_01980	411469.EUBHAL_00279	5.39e-290	791.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,25V3G@186806|Eubacteriaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
NIGDIANH_01981	411469.EUBHAL_00281	3.39e-128	365.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,25WJI@186806|Eubacteriaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NIGDIANH_01982	411469.EUBHAL_01468	4.08e-41	147.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,25URN@186806|Eubacteriaceae	186801|Clostridia	O	Mg chelatase-like protein	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NIGDIANH_01983	411469.EUBHAL_01469	2.54e-267	732.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,25VKT@186806|Eubacteriaceae	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
NIGDIANH_01984	411469.EUBHAL_02860	1.88e-37	137.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,25V1G@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NIGDIANH_01985	411469.EUBHAL_02859	2.11e-290	795.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,25V0E@186806|Eubacteriaceae	186801|Clostridia	P	Potassium uptake protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NIGDIANH_01986	411469.EUBHAL_02858	4.46e-148	417.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,25WED@186806|Eubacteriaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NIGDIANH_01987	411469.EUBHAL_01370	9.2e-87	254.0	COG1388@1|root,COG1388@2|Bacteria,1VKXM@1239|Firmicutes,24VM6@186801|Clostridia,25XS7@186806|Eubacteriaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NIGDIANH_01988	411469.EUBHAL_01369	6.56e-88	288.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,25VEA@186806|Eubacteriaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
NIGDIANH_01989	411469.EUBHAL_00229	0.0	966.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,25Y17@186806|Eubacteriaceae	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
NIGDIANH_01990	411469.EUBHAL_03061	1.13e-150	424.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,25V9I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NIGDIANH_01991	411469.EUBHAL_03060	3.28e-298	817.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,25UX9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NIGDIANH_01992	411469.EUBHAL_01345	6.06e-230	638.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,25UXB@186806|Eubacteriaceae	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
NIGDIANH_01993	411469.EUBHAL_01542	0.0	1013.0	COG0155@1|root,COG0155@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia,25UXE@186806|Eubacteriaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
NIGDIANH_01994	411469.EUBHAL_00382	4.22e-52	164.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NIGDIANH_01995	65393.PCC7424_0332	1.42e-53	189.0	COG0438@1|root,COG0438@2|Bacteria,1G9G3@1117|Cyanobacteria,3KKPR@43988|Cyanothece	1117|Cyanobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
NIGDIANH_01997	411459.RUMOBE_02163	6.06e-132	374.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01998	755731.Clo1100_2368	1.44e-20	84.3	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia,36NNW@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_01999	411459.RUMOBE_03465	2.06e-160	456.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3XYYM@572511|Blautia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NIGDIANH_02000	411469.EUBHAL_01322	0.0	875.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,25V7Y@186806|Eubacteriaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NIGDIANH_02001	411469.EUBHAL_01321	1.62e-58	181.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,25X1Y@186806|Eubacteriaceae	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
NIGDIANH_02002	411469.EUBHAL_01320	2.57e-107	313.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,25VQ5@186806|Eubacteriaceae	186801|Clostridia	S	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NIGDIANH_02003	411461.DORFOR_00658	0.0	924.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,27V0W@189330|Dorea	186801|Clostridia	F	Adenylosuccinate lyase C-terminus	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NIGDIANH_02004	411469.EUBHAL_00305	3.74e-250	705.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,25VNQ@186806|Eubacteriaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NIGDIANH_02005	411469.EUBHAL_00304	3.24e-94	282.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,25WHZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
NIGDIANH_02006	411469.EUBHAL_00304	2.82e-82	250.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,25WHZ@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
NIGDIANH_02008	411469.EUBHAL_03172	1.23e-44	144.0	2DQDV@1|root,33675@2|Bacteria,1VITX@1239|Firmicutes,24S3U@186801|Clostridia,25Z8I@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NIGDIANH_02009	411469.EUBHAL_03171	3.74e-167	469.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,25V1Y@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NIGDIANH_02010	411469.EUBHAL_00166	2.62e-246	687.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,25VF8@186806|Eubacteriaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NIGDIANH_02011	411469.EUBHAL_00165	3.72e-100	291.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,25WB7@186806|Eubacteriaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NIGDIANH_02012	411469.EUBHAL_00164	3.61e-82	249.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,25WA9@186806|Eubacteriaceae	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NIGDIANH_02013	742765.HMPREF9457_02807	1.46e-137	407.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,27VAI@189330|Dorea	186801|Clostridia	GM	RmlD substrate binding domain	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
NIGDIANH_02014	478749.BRYFOR_09353	1.89e-262	723.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
NIGDIANH_02015	411469.EUBHAL_00039	5.19e-59	182.0	2E3UX@1|root,32YS7@2|Bacteria,1VIM3@1239|Firmicutes,24THX@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF997)	-	-	-	-	-	-	-	-	-	-	-	-	DUF997
NIGDIANH_02016	411469.EUBHAL_00038	7.26e-133	389.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia,25VC3@186806|Eubacteriaceae	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	panF	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
NIGDIANH_02017	515620.EUBELI_20197	5.41e-89	274.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,25VG0@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NIGDIANH_02021	411469.EUBHAL_00094	1.44e-83	246.0	arCOG10654@1|root,32SVP@2|Bacteria,1VCYZ@1239|Firmicutes,24PR9@186801|Clostridia,25XGK@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02023	411469.EUBHAL_00097	1.58e-138	392.0	2DM2Z@1|root,31HGC@2|Bacteria,1VAI4@1239|Firmicutes,24N79@186801|Clostridia,25YUX@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF4125)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4125
NIGDIANH_02024	411469.EUBHAL_01990	4.28e-176	491.0	COG1028@1|root,COG1028@2|Bacteria,1TRND@1239|Firmicutes,2490V@186801|Clostridia,25VTF@186806|Eubacteriaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NIGDIANH_02025	411469.EUBHAL_01991	1.79e-285	780.0	COG5441@1|root,COG5441@2|Bacteria,1TQ3W@1239|Firmicutes,24A9D@186801|Clostridia,25W0H@186806|Eubacteriaceae	186801|Clostridia	S	Uncharacterised protein family (UPF0261)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0261
NIGDIANH_02026	411469.EUBHAL_03184	7.97e-209	578.0	COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,24AMC@186801|Clostridia,25WT9@186806|Eubacteriaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NIGDIANH_02028	411469.EUBHAL_00752	1.44e-44	160.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,25V3M@186806|Eubacteriaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NIGDIANH_02029	411469.EUBHAL_00753	6.71e-93	271.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,25WFJ@186806|Eubacteriaceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NIGDIANH_02031	411469.EUBHAL_02871	0.0	1036.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,25V4A@186806|Eubacteriaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
NIGDIANH_02032	411469.EUBHAL_02748	0.0	1154.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,25V5B@186806|Eubacteriaceae	186801|Clostridia	S	of ABC transporters with duplicated ATPase	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NIGDIANH_02033	411469.EUBHAL_02673	2.12e-214	593.0	28HEE@1|root,2Z7QU@2|Bacteria,1TVQR@1239|Firmicutes,248QB@186801|Clostridia,25Y88@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
NIGDIANH_02034	411469.EUBHAL_02672	1.01e-153	432.0	COG1961@1|root,COG1961@2|Bacteria,1U31Z@1239|Firmicutes,249GR@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NIGDIANH_02035	742765.HMPREF9457_01099	7.11e-85	252.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,27VH8@189330|Dorea	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NIGDIANH_02036	411461.DORFOR_01074	6.71e-93	271.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,27X9S@189330|Dorea	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NIGDIANH_02037	411461.DORFOR_01064	1.13e-87	257.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24NZ2@186801|Clostridia,27VRJ@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02038	1280698.AUJS01000065_gene671	2.6e-258	714.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
NIGDIANH_02039	1280698.AUJS01000033_gene2068	7.78e-87	257.0	COG0454@1|root,COG0456@2|Bacteria,1V1VV@1239|Firmicutes,25CUX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NIGDIANH_02040	622312.ROSEINA2194_03680	2.73e-201	557.0	COG2207@1|root,COG2207@2|Bacteria,1UZ0Q@1239|Firmicutes,24YIV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NIGDIANH_02041	622312.ROSEINA2194_03681	9.01e-257	702.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
NIGDIANH_02042	411469.EUBHAL_01592	0.0	903.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,25VBX@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NIGDIANH_02043	1293054.HSACCH_00252	3.13e-10	60.5	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia	186801|Clostridia	CQ	Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NIGDIANH_02044	411469.EUBHAL_00172	1.46e-283	774.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,25V9U@186806|Eubacteriaceae	186801|Clostridia	C	Metallo-beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NIGDIANH_02045	411469.EUBHAL_00171	6.59e-91	281.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NIGDIANH_02047	411469.EUBHAL_01826	4.84e-70	219.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,25V2D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NIGDIANH_02048	411469.EUBHAL_01827	1.6e-290	793.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,25V9D@186806|Eubacteriaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NIGDIANH_02049	411469.EUBHAL_02372	3.62e-68	215.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,25V14@186806|Eubacteriaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NIGDIANH_02050	411469.EUBHAL_00832	0.0	1031.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,25UT1@186806|Eubacteriaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NIGDIANH_02051	411459.RUMOBE_01673	4.45e-37	132.0	2DJJ8@1|root,306CG@2|Bacteria,1TZJ0@1239|Firmicutes,25N4G@186801|Clostridia,3Y1ZT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02054	397291.C804_02095	1.35e-13	68.6	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,27JUZ@186928|unclassified Lachnospiraceae	186801|Clostridia	OU	Clp protease	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NIGDIANH_02055	397291.C804_02095	9.71e-81	245.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,27JUZ@186928|unclassified Lachnospiraceae	186801|Clostridia	OU	Clp protease	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NIGDIANH_02056	397291.C804_02094	6.44e-18	83.2	2BQXJ@1|root,32JUS@2|Bacteria,1UR62@1239|Firmicutes,258ZV@186801|Clostridia,27S39@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02057	411460.RUMTOR_02561	3.77e-207	578.0	COG4924@1|root,COG4924@2|Bacteria,1V0BQ@1239|Firmicutes,24DRK@186801|Clostridia,3Y1YU@572511|Blautia	186801|Clostridia	S	COG NOG13188 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
NIGDIANH_02058	471875.RUMLAC_00317	1.18e-98	286.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WIWI@541000|Ruminococcaceae	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NIGDIANH_02059	411469.EUBHAL_00549	1.77e-59	193.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,25W97@186806|Eubacteriaceae	186801|Clostridia	J	Threonyl and Alanyl tRNA synthetase second additional domain	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NIGDIANH_02061	411469.EUBHAL_02383	0.0	884.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,25V78@186806|Eubacteriaceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NIGDIANH_02062	411469.EUBHAL_00564	3.03e-64	197.0	COG3862@1|root,COG3862@2|Bacteria,1VHQB@1239|Firmicutes,24T0T@186801|Clostridia,25XGU@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
NIGDIANH_02063	411469.EUBHAL_00565	3.83e-295	808.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,25VE0@186806|Eubacteriaceae	186801|Clostridia	C	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
NIGDIANH_02064	742765.HMPREF9457_01507	8.38e-98	284.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,27VN5@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02065	411469.EUBHAL_01298	2.17e-65	202.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,25WW2@186806|Eubacteriaceae	186801|Clostridia	H	5-formyltetrahydrofolate cyclo-ligase	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
NIGDIANH_02066	411469.EUBHAL_01299	4.54e-144	406.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,25WHX@186806|Eubacteriaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NIGDIANH_02067	742765.HMPREF9457_01187	0.0	1165.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,27V21@189330|Dorea	186801|Clostridia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NIGDIANH_02068	411469.EUBHAL_01216	2.39e-187	521.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,25WR5@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NIGDIANH_02069	411469.EUBHAL_01217	2e-205	568.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,25VDW@186806|Eubacteriaceae	186801|Clostridia	E	histidinol phosphate phosphatase, HisJ family	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NIGDIANH_02070	411469.EUBHAL_02898	3.82e-141	399.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,25W3I@186806|Eubacteriaceae	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NIGDIANH_02071	411469.EUBHAL_02897	4.6e-123	352.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,25XFM@186806|Eubacteriaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NIGDIANH_02072	411469.EUBHAL_02896	3.21e-92	290.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,25VMN@186806|Eubacteriaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NIGDIANH_02073	411469.EUBHAL_01950	1.31e-282	774.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NIGDIANH_02074	411469.EUBHAL_02171	0.0	1055.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,249NB@186801|Clostridia,25UX7@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NIGDIANH_02075	411469.EUBHAL_01925	3.56e-56	174.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,25XB7@186806|Eubacteriaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NIGDIANH_02076	37659.JNLN01000001_gene1274	1.36e-74	243.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,36FW7@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NIGDIANH_02077	411463.EUBVEN_02569	1.72e-40	133.0	COG1476@1|root,COG1476@2|Bacteria,1VCCB@1239|Firmicutes,25BIG@186801|Clostridia,25X3K@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulators	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NIGDIANH_02078	411469.EUBHAL_01988	5.41e-34	127.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25W0C@186806|Eubacteriaceae	186801|Clostridia	H	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.53	ko:K00880	ko00040,ko00053,map00040,map00053	-	R01901,R07127	RC00002,RC00017,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NIGDIANH_02079	411469.EUBHAL_01989	4.2e-208	575.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,25C7M@186801|Clostridia,25Y7Z@186806|Eubacteriaceae	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
NIGDIANH_02080	411469.EUBHAL_01684	8.72e-198	550.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,25V47@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NIGDIANH_02081	411469.EUBHAL_01682	1.01e-88	262.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,25W4A@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NIGDIANH_02082	411469.EUBHAL_02939	1.26e-122	349.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,25WM3@186806|Eubacteriaceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NIGDIANH_02083	411469.EUBHAL_02981	0.0	931.0	COG0169@1|root,COG1418@1|root,COG0169@2|Bacteria,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,25WKW@186806|Eubacteriaceae	186801|Clostridia	E	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NIGDIANH_02084	411469.EUBHAL_01242	2.05e-166	465.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,25VEN@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
## 1900 queries scanned
## Total time (seconds): 244.36064958572388
## Rate: 7.78 q/s