LOCUS       c00054_gnlPro..         9263 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NIGDIANH_54.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:53:29
            Original ID  :: gnl|Prokka|NIGDIANH_54
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9263
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9263
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1333:7451]"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1334..7451
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /neighbourhood="10000"
                     /product="acetate2butyrate"
                     /protocluster_number="1"
     cand_cluster    1..9263
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (POR or POR_N or PFOR_II) and
                     minimum(4, [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF,
                     ETF_alpha, HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and
                     minimum(1, [EC1_2-faecali, ECH1_Enoyl_CoA_DH1,
                     ECH1_Enoyl_CoA_DH2, ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4,
                     Thiolase_C]))"
                     /kind="single"
                     /product="acetate2butyrate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9263
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="acetate2butyrate"
                     /region_number="1"
                     /rules="(not (POR or POR_N or PFOR_II) and minimum(4,
                     [Acyl-CoA_dh_1, Acyl-CoA_dh_2, ECH_2, ETF, ETF_alpha,
                     HCDH_N, Thiolase_N, ketoacyl-synt]) and HCDH and minimum(1,
                     [EC1_2-faecali, ECH1_Enoyl_CoA_DH1, ECH1_Enoyl_CoA_DH2,
                     ECH1_Enoyl_CoA_DH3, ECH1_Enoyl_CoA_DH4, Thiolase_C]))"
                     /tool="gutsmash"
     CDS             1334..2515
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Thiolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_1"
                     /sec_met_domain="Thiolase_N (E-value: 2.8e-104, bitscore:
                     337.3, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 5.6e-51, bitscore:
                     160.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKKVVLAGACRTAIGTMGGGLSTVPAADLGSIVIKEALKRTNVP
                     ADQVDEVLMGCVIQAGLGQNVARQASINAGLPIEVPAVTINVVCGSGLNCVNLAATKIL
                     AGEADIVIAGGMENMSLAPFCLDKARFGYRMNNGVLKDCMVNDALTDAFNQYHMGITAE
                     NVAEQWHLTREELDEFSANSQQKATAAIEAGKFKDEIVPVEVKLKKKTVVVDTDEGPRP
                     GTTAESISKLRPAFKKDGIVTAANSSGINDGAACVVVMSEEKAKELGVTPMATWIAGAL
                     GGVDPSIMGVGPVASTKKVLAKTGMSIDDFDLIEANEAFAAQSLAVGRELGINPEKLNV
                     NGGAIALGHPVGASGCRILVTLLHEMQKRDAKKGLATLCIGGGMGCSTIVERD"
     CDS             2646..3431
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: EC1_2-faecali"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_2"
                     /sec_met_domain="EC1_2-faecali (E-value: 8.7e-92, bitscore:
                     296.2, seeds: 67, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFIDYEVDGQVGIITINRPKALNALNSEVLKDLDATIDAVDLDA
                     IRCLIITGAGEKSFVAGADIGEMSTLTKAEGEAFGKAGNDVFRKIETLPIPVIAAINGF
                     ALGGGCEISMSCDIRLCSENAVFGQPEVGLGITPGFGGTQRLARIVGPGKAKQLIYTAR
                     NIKAAEAYRIGLVNEVYPLEELMPQAKKMAKGIAKNAPIAVRACKKAINEGLEVGMDEA
                     IVIEEKLFGSCFETEDQKYGMAFFLDKNKEKVKEPFKNC"
     CDS             3500..4339
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: HCDH_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_3"
                     /sec_met_domain="HCDH (E-value: 5.7e-39, bitscore: 122.1,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 4.9e-62, bitscore: 198.3,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGVIGAGTMGSGIAQAFAQTEGYEVYLCDINDEFAANGKKKIA
                     KGFEKRVARGKMDQAKADAILAKITTGTKDICTDADLVVEAALEVMEVKQQTFKELQDI
                     VPATCMFATNTSSLSITQIGAGLDRPVIGMHFFNPAPVMKLIEVIAGLNTPDEMVEKIK
                     AISVEIGKTPVQVEEAAGFVVNRILIPMINEAVGIYADGVASVEGIDTAMKLGANHPMG
                     PLALGDLVGLDICLAIMEVLYNETGDPKYRPHPLLRKMVRGGKLGQKTGIGFYDYSK"
     CDS             4440..5594
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_4"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.8e-53, bitscore:
                     168.4, seeds: 49, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.5e-31, bitscore:
                     97.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-41, bitscore:
                     131.3, seeds: 796, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLSKKHEMARQLFKEFAENEVKPLAQEVDETEHFPEETVAKM
                     QKLGFMGIPVPKEYGGQGCDPLTYIMCVEELSKVCGTTGVIVSAHTSLCADPILTYGTE
                     EQKQKYLVPLAKGEKLGAFGLTEPGAGTDAQGVQTKAVLDGDEWVLNGSKCFITNGSYA
                     DYYIIIAITSVDTDARGRKKKKFSAFIVEKGTPGFTFGTKEKKMGIRGSSTYELIFEDC
                     RIPAENLLGKKGKGFNIAMHTLDGGRIGIAAQALGIAEGALDATIAYVKERKQFGRAIA
                     AQQNTQFQLANMATQVEAAKLLVYKAAMAKATQRVYSVEAAKAKLFAAETAMDVTTKCV
                     QLLGGYGYIREYDVERMMRDAKITEIYEGTSEVQRMVISGNLLK"
     CDS             5609..6394
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 163.8;
                     E-value: 1.3e-50)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_5"
                     /sec_met_domain="ETF (E-value: 1.8e-51, bitscore: 163.8,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIVVCVKQVPDTKGGVKFKPDGTLDRAAMLTIMNPDDKAGLEAA
                     LRIKDETGAEVTVVTMGLPKAEEVLREAMAMGADKGILVTDRVLGGADTWATSTTIAGA
                     LRNIDYDLIITGRQAIDGDTAQVGPQIAEHLDLPLISYAQDIKVEGDSVIVQRQYDDRY
                     HVLKAKMPCVITALSELNEPRYMTPGGIFDAYDAEITTWGRKDLKDVDDSNLGLAGSPT
                     QIAKASDKVRKGKGVMMTAETAEEGVEYIMDKLLTKHVI"
     CDS             6411..7451
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     acetate2butyrate: ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 167.1;
                     E-value: 1.2e-51)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_6"
                     /sec_met_domain="ETF (E-value: 1.8e-52, bitscore: 167.1,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 5.2e-39, bitscore:
                     121.6, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNRMNLEQYKGVFIYAQQVDNKIDAIALELLGKANDLAADLGTDV
                     TAVLIGSDVKGLVDELAEYGADKVIVVDDPELKEYRTEPYTHALASVINEYKPDILLVG
                     ATAIGRDLGPRVSARVATGLTADCTVLEIGEFKARGDKEPRQGQLLMTRPAFGGNTIAT
                     IACPNHRPQMATVRPGVMQKKEPVAGAKAEVIEYNPGFTPNDKYVEILDIVKSVTETVD
                     IQAAKILVSGGRGVGSAENFALLDDLAEALGGTVSCSRAVVDNGWKPKDLQVGQTGKTV
                     RPNVYFAIGISGAIQHVAGMEESDIIIAINKDPDAPIFDVADYGIVGDALKIVPKLTEA
                     IKAQVK"
     CDS             8242..8532
                     /locus_tag="ctg54_7"
                     /transl_table=11
                     /translation="MAQIIASTKEISNKRESLIVLSNSLKNKISLLETLGNSLNSMWEG
                     AAKEKYVKQLKTDISKMRNLLKTILEFILILEKIIAIYNKAEKKNEATAVS"
     CDS             8544..8861
                     /locus_tag="ctg54_8"
                     /transl_table=11
                     /translation="MADLINVTPEKLKATASSFQQAGKDVKKTTSDMLQLVRGISSSIW
                     SGEASSIYLGKFNGLDADIAKMCKMIEEESQHLTTIAQEYQLAEEQNKQVAATLKNNVI
                     A"
     CDS             8886..9263
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MLSVMIFCHDKREGDLIGKICNQCVALIDKEFLRNFIISDEEYHQ
                     VNIEGIQPPDLLVVEITGIEDLCRAKRIRGIFPRGRLLVVSTNQISAESYLIPEVSPDM
                     LLLKPYVYAKACRIIYRSLTWC"
ORIGIN
        1 aagcacagcg atgtgtggag ttgactgtta ctaatcggtc gaaagcttga ccttaaaaag
       61 tacttgcaaa gttcaaagag atatgatata atgtgtgtgg ttttcagggt atgacacctg
      121 acaatattcc tcgatagctc agtcggtaga gcacgcggct gttaaccgcg ctgtcgtagg
      181 ttcaagtcct actcggggag tctggctcct tggtcaagtg gttaagacac cgccctttca
      241 cggcggtaac atgggttcaa atcccgtagg agtcacttgt ggcgtcgtag ccaagtggta
      301 aggcagaggt ctgcaacacc ttcatcacca gttcaaatct ggtcgacgcc tcttaaaaga
      361 gactaagtga ttagtctctt tttagtattt ctttttaatt taatatcgcg gggtagagca
      421 gtctggtagc tcgtcgggct cataacccgg aggtcgttgg ttcaaatcct tcccccgcaa
      481 tttgaggaac atcggtacat tggtatcggt gtttttttat ttgtttaaac tgacgcaata
      541 gtaaaacccg ctataagtct atctgtgact ttagtcgcgg cgtgttgaat gttcgcttag
      601 acgctcgtat ccaacacttg ctccgaggcc acagatagac ttatagcgag ctttactatt
      661 gctggctttg aaggaaacaa agtaaaaatt cttagatgtg caacgattcg atgttgggga
      721 gagtgtgtga atttaaaata tagatttttt ggtattgatt ttgttaatat aattacaatg
      781 ataaaaacaa attgcaatac aaaatataca taatttcatc tacagctatc cgggcaattt
      841 tcaaatccct ccatatagac attctaaact aaatccttcc aacagataga aaagccagag
      901 atactttatg taccatatgc tttatttcac tgtgcaaaat gccataaaac tcactccaaa
      961 gccacatctg gcaggtaaag tatctctggt ttttcgtcta ttagccaact cagaatgtct
     1021 atttcttcac atatttaggc agttttttgt attttgtttc cttttttcac aaaatcagaa
     1081 aattaatcaa tagagaatgt ccatagatat aagaagaaat aaaggtaaaa ttaattaaaa
     1141 caacgatgga ttttgtattc aaaagtgacg aaactgtgaa tctttcataa atgaaaatat
     1201 taattaaaaa tttttttata atcttgttgc aaagcaaaga agattgtgat aagattaaca
     1261 catatcgtac tagaaatgct ctagcaaagc aactatcaaa taatattgat aacttaaatg
     1321 gaggaatgaa actatggcaa agaaagttgt attagcaggt gcttgtcgta ccgcaatcgg
     1381 aacaatgggt ggtggattaa gcacagtacc agctgcagat ttaggaagca tcgtaattaa
     1441 agaagcgtta aagagaacta acgtacctgc tgatcaggta gacgaagtat taatgggatg
     1501 tgttatccag gctggtcttg gacagaacgt tgctcgtcag gcttctatta atgcaggctt
     1561 accaatcgaa gtacctgctg taacaattaa cgtagtttgt ggttccggtc ttaactgtgt
     1621 taaccttgct gctacaaaga ttttagcagg tgaggctgat atcgttatcg ctggtggtat
     1681 ggaaaacatg tcattagctc cattctgctt agacaaagct cgttttggat acagaatgaa
     1741 caatggcgta ttaaaagact gtatggttaa cgatgcatta acagatgctt tcaatcagta
     1801 ccatatgggt attacagctg aaaacgttgc agaacagtgg catttaacaa gagaagagtt
     1861 agatgagttc tccgctaatt cacagcagaa agctacagca gctatcgaag ctggtaagtt
     1921 caaagatgag attgttcctg tagaagttaa acttaaaaag aaaacagttg ttgtagatac
     1981 agatgaggga ccacgtcctg gaacaacagc agaaagtatt tctaaattac gtcctgcttt
     2041 caagaaagat ggtatcgtaa cagctgccaa ctcttcaggt attaacgatg gtgctgcttg
     2101 tgttgttgtt atgagcgaag aaaaagctaa agaattaggt gtaactccaa tggctacatg
     2161 gatagcagga gcattaggcg gagttgatcc ttctatcatg ggtgttggac cagttgcttc
     2221 tactaagaaa gttcttgcaa aaacaggcat gagcattgat gactttgact taatcgaagc
     2281 taacgaagct ttcgcagctc agtcattagc agtaggaaga gaattaggaa tcaacccaga
     2341 gaagttaaat gttaatggtg gagctattgc tcttggacat ccagtaggag catcaggatg
     2401 ccgtatcctc gttacattat tacatgagat gcagaaacgt gatgctaaga aaggtcttgc
     2461 tacactgtgt atcggtggtg gtatgggctg ctcaacaatc gttgaaagag actaatcacg
     2521 tatagaatga ttacatatat ccgggttcag ttttcgaatc cggttatatc aattacatag
     2581 tttgtaacta tttaattatc tagattgaat agttagctaa tgtaatctga aaggagatac
     2641 atacaatggg atttatcgat tatgaagtag atggccaggt tggtattatc accatcaatc
     2701 gtccaaaggc tttaaatgct ttaaacagtg aagtattaaa agatttagat gcaactattg
     2761 atgcagtaga tttagacgca atcagatgtc ttatcattac tggtgctgga gagaaatctt
     2821 tcgtagcagg tgctgatatc ggagagatga gtacacttac aaaagcagaa ggcgaagctt
     2881 tcggtaaagc tggtaatgat gtattcagaa agattgaaac acttccaatc cctgttatcg
     2941 cagcaatcaa cggattcgct ttaggcggtg gctgtgagat ttctatgagc tgtgacatca
     3001 gactttgctc tgagaatgca gtgtttggac agccagaagt tggtcttgga atcacacctg
     3061 gttttggtgg aacacagaga cttgctcgta tcgtaggacc tggaaaagca aaacagttaa
     3121 tctatactgc tcgcaatatt aaagcagcag aagcttacag aatcggtctg gttaacgaag
     3181 tttatccact cgaagagtta atgcctcagg ctaagaagat ggcaaagggt attgcaaaga
     3241 acgcacctat cgcagttcgt gcatgtaaga aagctatcaa cgaaggttta gaagtaggaa
     3301 tggatgaagc tatcgtaatc gaagagaagt tatttggcag ctgcttcgag acagaagacc
     3361 agaaatacgg aatggcattc ttccttgaca aaaacaaaga aaaagtaaaa gagccattta
     3421 aaaactgcta attaatcaat tatacatatt gtattattaa ttatcggaat acattacatt
     3481 ttataggagg tttcaaacaa tgaaagttgg agttattggc gcaggtacaa tgggatcagg
     3541 tattgctcag gcattcgcac agacagaagg atacgaagta tatttatgtg atatcaacga
     3601 tgaatttgct gcaaatggta aaaagaaaat cgctaaagga tttgaaaaga gagtagcaag
     3661 aggaaaaatg gatcaggcta aagctgatgc aatccttgct aagattacta ctggtacaaa
     3721 agatatctgt acagatgctg atttagtagt agaagcagct cttgaagtta tggaagttaa
     3781 acagcagaca tttaaagaat tacaggatat cgttcctgca acatgtatgt ttgcaacaaa
     3841 tacatcttct ttatctatta cacagattgg tgcaggactt gacagaccag ttatcggaat
     3901 gcatttcttc aacccagctc cagttatgaa attaattgaa gttatcgctg gtcttaatac
     3961 accagatgaa atggttgaaa agattaaagc tatctccgta gaaatcggca aaacacctgt
     4021 acaggtagaa gaagctgcag gattcgtagt taacagaatt ttaatcccaa tgattaacga
     4081 agcagttggc atttatgctg atggtgttgc ttctgttgaa ggtatcgaca cagctatgaa
     4141 gttaggtgct aaccatccaa tgggacctct cgctttagga gatttagttg gtcttgatat
     4201 ctgccttgca atcatggaag tattatataa tgaaacagga gatcctaagt atcgtccaca
     4261 tccattatta agaaagatgg ttcgtggtgg aaaattaggt cagaagactg gtattggatt
     4321 ctacgattac agcaaataat taaaaaagtg aatacggccg tggggactat gctctgcgtc
     4381 tccacggctt ttaaggtggt tctccacccc aataaccaat ttattatgga ggaatgaaaa
     4441 tggatttcac attaagcaaa aagcatgaaa tggctagaca gctctttaaa gagttcgctg
     4501 aaaacgaagt taaacctctt gctcaggagg ttgacgagac agaacatttt ccagaagaaa
     4561 ccgttgcaaa aatgcaaaaa ttaggtttca tgggaattcc tgtgccaaaa gaatatggcg
     4621 gacagggttg tgatccttta acatacatta tgtgtgttga agagttatct aaagtttgtg
     4681 gtacaacagg tgttattgta tccgcacata catcattgtg tgcagatcca attcttactt
     4741 acggtactga agaacagaaa cagaaatatc ttgttccact tgcaaagggt gaaaagttag
     4801 gtgctttcgg tcttacagag ccaggtgctg gtactgacgc tcagggtgtt cagacaaagg
     4861 ctgttttaga tggtgacgag tgggtattaa acggatctaa atgtttcatc actaacggtt
     4921 cttatgctga ttactatatt atcatcgcta tcacaagtgt tgatacagat gcaagaggaa
     4981 gaaagaaaaa gaaattctcc gcatttatcg tagaaaaagg aactccagga tttacatttg
     5041 gtacaaaaga aaagaaaatg ggtatccgtg gatcatctac atatgaatta atctttgaag
     5101 attgtcgtat cccggctgaa aacttacttg gtaagaaggg taaaggtttc aacatcgcta
     5161 tgcacacact tgatggtgga cgtatcggta ttgcagctca ggctcttggt atcgcagaag
     5221 gtgctttaga tgctacaatt gcttatgtta aagaaagaaa acagtttggc agagcaattg
     5281 ctgcacagca gaatacacag ttccagcttg ctaatatggc tacacaggta gaagctgcta
     5341 agttacttgt ttataaagca gcaatggcaa aagcaacaca gagagtatac tccgtagaag
     5401 cagcaaaagc taaattattt gcagcagaaa cagctatgga tgtaacaact aagtgtgttc
     5461 agttacttgg tggttatggt tacatcagag agtacgacgt agaacgtatg atgcgtgacg
     5521 ctaagatcac agaaatctac gaaggaactt cagaagttca gcgtatggtt atttctggta
     5581 acttattgaa ataaggaggg aaaatactgt gaaaatcgta gtatgtgtta aacaggtacc
     5641 tgatacaaaa ggtggagtta agtttaaacc agacggaact cttgatagag cagctatgct
     5701 tactatcatg aatccagatg ataaggcagg tcttgaagct gcccttagaa taaaagatga
     5761 aacaggcgca gaagtaacag tagttactat gggtcttcca aaagcagaag aagttctgcg
     5821 tgaagctatg gcaatgggtg ctgacaaggg tatccttgta acagaccgtg ttttaggtgg
     5881 agctgataca tgggcaacat ctacaacaat cgctggagca cttagaaata ttgattatga
     5941 tttaatcatc acaggtcgtc aggctatcga tggtgatact gctcaggtag gacctcagat
     6001 tgctgaacac ttagatcttc ctttaatttc ctatgctcag gatatcaaag ttgaaggtga
     6061 cagtgtaatc gttcagagac agtatgacga cagatatcat gttttaaaag ctaaaatgcc
     6121 atgtgttatc acagcacttt ccgaattaaa tgagccacgt tatatgactc caggcggaat
     6181 ctttgatgca tatgatgcag aaattactac atggggaaga aaagacctta aagatgttga
     6241 tgacagcaac ttaggtcttg caggttctcc aactcagatc gcaaaagctt ctgataaggt
     6301 acgtaaaggt aaaggtgtca tgatgacagc tgaaacagca gaagaaggcg ttgagtacat
     6361 catggacaaa ctgttaacaa agcatgttat ctaattgtaa aggaaatgtg gtgaatagaa
     6421 tgaatttaga acaatataaa ggtgtattta tctatgctca gcaggttgac aataagattg
     6481 atgccattgc tttagaatta cttggaaaag caaatgacct tgctgcagat ttaggaacag
     6541 acgtaacagc agttttaatc ggttctgacg taaaaggctt agttgatgaa cttgctgaat
     6601 acggcgcaga taaagttatc gtagttgatg accctgaatt aaaagaatac agaacagagc
     6661 catatacaca tgcactggca tctgttatca acgaatacaa accggacatt cttctggttg
     6721 gagcaacagc aatcggtcgt gacttaggac ctcgtgtttc tgcaagagtt gcaacaggtc
     6781 ttacagcaga ctgtactgtt cttgaaattg gtgaattcaa agctcgtgga gataaagaac
     6841 ctcgtcaggg tcagttatta atgactcgtc ctgcattcgg tggtaacaca atcgctacaa
     6901 tcgcttgtcc taaccatcgt ccacagatgg ctacagttcg tcctggtgtt atgcagaaga
     6961 aagagcctgt tgcaggtgca aaggcagaag ttattgagta caatccagga tttactccaa
     7021 atgacaaata tgttgagatt cttgacattg taaaatctgt tacagaaaca gttgatatcc
     7081 aggctgctaa gattcttgta tctggcggac gtggagttgg ctctgctgag aactttgcat
     7141 tattagacga tttagcagag gcacttggcg gaacagtttc ctgctcacgt gcagttgttg
     7201 ataatggttg gaaaccaaaa gatttacagg ttggccagac tggtaagaca gttcgtccta
     7261 atgtttattt tgcaatcggt atttccggag caatccagca cgtagctggt atggaagaat
     7321 ctgatatcat cattgctatc aataaagacc cagatgcacc tatctttgat gtagctgatt
     7381 acggtattgt tggcgatgca ttaaagattg ttcctaagtt aacagaggca atcaaagctc
     7441 aggttaaata atttcaaatc atatcagact cattagatta tgtgagttac tgattgagga
     7501 ttgaaactta gattttttgt ggaagtctag tatatgcatt ctcagatgtt ttgtgtattg
     7561 acgattcatt attaaaagaa gcatatagga gatttgtgct gaactctata aaatgtattt
     7621 atgcagggaa tctttttgaa gattccctgt taaagtgaga tagtaggact acagtttata
     7681 actgtggtct tttttacttt cattcagttg gcatagcccg ctacgccgtc ttcattcagg
     7741 aaaaattccc cacaaattgt aacgcacatc ttgcaaaagc atttttcaaa ctcgttctag
     7801 tatagcatcc attcagtgtt tatgaataat tatttgatag ttcacaataa aagatgcacg
     7861 aagtaaatta gaaaaactat atccaataat attttagaaa ttagatagat gctatactag
     7921 agcgtgtttg aaaaatcatt cctacaatct gcacgcccca atttgcggta tattttgcct
     7981 tcattcagtt gacgtagccc gctacgccgc cctcattcag gtaaaatctc ccacaaattg
     8041 taacgcacat cttgcagaaa gcatttttca aacacgctct agtaaaatac gtcattttta
     8101 ttttatatat aataaaaagt aaacataata aagaagtact tatcacaaaa taaacataat
     8161 ttgtcaaaaa tagtggaaat taattccaaa tatgttataa tactcttgca gcagttaacc
     8221 gagatatgag aggaggcatt tatggcacaa attattgctt caacaaaaga aatatctaat
     8281 aagagagagt cactgatagt attgagtaat tccttaaaga ataagatttc gcttttagaa
     8341 actttgggga acagtcttaa ttctatgtgg gaaggcgctg caaaagagaa gtatgtaaag
     8401 caacttaaga cagacatttc aaagatgcgg aacttactta agacaatttt ggaatttata
     8461 ttgatactag agaagattat tgcaatctat aataaagcag agaagaagaa tgaggcgaca
     8521 gcggtaagct aggaggggga tttatggcag atttaattaa tgtaactcca gagaagttaa
     8581 aggcgacagc aagttctttc caacaggcag gaaaggacgt taagaaaact acttctgata
     8641 tgcttcagtt agtgagggga attagtagtt ccatctggag tggagaggcg agtagtatat
     8701 atcttggtaa gtttaatgga ttggatgccg atatcgccaa gatgtgcaag atgatagaag
     8761 aagaatcaca gcatttgaca acaattgcac aggaatacca gttagcagaa gaacagaata
     8821 aacaggttgc ggcaacatta aagaataatg taattgctta gattgtatag acagatgaat
     8881 agattatgct gtcagttatg attttttgtc atgacaaaag agaaggagat ttaattggaa
     8941 agatatgtaa tcagtgtgtg gcgcttatag ataaagagtt tttacgtaat tttatcataa
     9001 gcgatgaaga gtatcatcag gtgaatatag agggaataca gccgccagat ttacttgtag
     9061 tagaaatcac aggtatagag gatttatgca gagcgaaacg aataaggggg attttcccga
     9121 gaggacgatt gctagttgta agtactaatc agatttcagc agagtcctat ttaattccgg
     9181 aagtttcacc agatatgctt ttactgaaac catatgtata tgcgaaagct tgtaggatta
     9241 tataccgaag tcttacatgg tgt
//
