Select genomic region:
Overview
1.1
1.2
3.1
4.1
4.2
5.1
13.1
17.1
19.1
52.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 176,857 | 214,506 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 1.2 | PFOR_II_pathway | SCFA | 218,898 | 242,434 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%

c00003_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_3)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 3.1 | Rnf_complex | E-MGC | 84,071 | 105,392 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%

c00004_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_4)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 4.1 | Rnf_complex | E-MGC | 24,159 | 49,170 | Rnf complex C. sporogenes | RNF | 100%
Region 4.2 | succinate2propionate | SCFA | 62,803 | 88,122 | Succinate to propionate B. theta | PRO | 33%

c00005_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_5)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 5.1 | GR_eut-pdu-related | Putative | 1 | 20,403 | Propanediol degradation S. enterica | PDU | 33%

c00013_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_13)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 13.1 | TPP_AA_metabolism | Putative | 13,694 | 42,410 |

c00017_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_17)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 17.1 | Acetyl-CoA_pathway | SCFA | 28,002 | 56,986 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%

c00019_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_19)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 19.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 23,062 | 54,510 |

c00052_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_52)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 52.1 | Others_HGD_unassigned | Putative | 1 | 10,817 |

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | GR_AA_metabolism,Pyruvate2acetate-formate | SCFA | 176,857 | 214,506 | Pyruvate to acetate and formate C. acetobutylicum | PFL_acetate | 100%
Region 1.2 | PFOR_II_pathway | SCFA | 218,898 | 242,434 | PFOR II pathway B. thetaiotaomicron | PFORII | 100%
Region 3.1 | Rnf_complex | E-MGC | 84,071 | 105,392 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 14%
Region 4.1 | Rnf_complex | E-MGC | 24,159 | 49,170 | Rnf complex C. sporogenes | RNF | 100%
Region 4.2 | succinate2propionate | SCFA | 62,803 | 88,122 | Succinate to propionate B. theta | PRO | 33%
Region 5.1 | GR_eut-pdu-related | Putative | 1 | 20,403 | Propanediol degradation S. enterica | PDU | 33%
Region 13.1 | TPP_AA_metabolism | Putative | 13,694 | 42,410 |
Region 17.1 | Acetyl-CoA_pathway | SCFA | 28,002 | 56,986 | Acetyl-CoA pathway B. hydrogenotrophica | Acetate | 61%
Region 19.1 | Others_HGD_unassigned,TPP_AA_metabolism | Putative | 23,062 | 54,510 |
Region 52.1 | Others_HGD_unassigned | Putative | 1 | 10,817 |

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_2)
  c00006_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_12)
  c00014_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_16)
  c00018_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_18)
  c00020_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_32)
  c00033_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_33)
  c00034_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_51)
  c00053_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_77)
  c00078_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_83)
  c00084_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_84)
  c00085_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_85)
  c00086_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_86)
  c00087_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_87)
  c00088_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_88)
  c00089_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_89)
  c00090_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_90)
  c00091_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_91)
  c00092_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_92)
  c00093_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_93)
  c00094_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_94)
  c00095_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_95)
  c00096_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_96)
  c00097_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_97)
  c00098_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_98)
  c00099_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_99)
  c00100_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_100)
  c00101_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_101)
  c00102_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_102)
  c00103_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_103)
  c00104_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_104)
  c00105_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_105)
  c00106_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_106)
  c00107_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_107)
  c00108_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_108)
  c00109_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_109)
  c00110_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_110)
  c00111_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_111)
  c00112_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_112)
  c00113_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_113)
  c00114_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_114)
  c00115_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_115)
  c00116_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_116)
  c00117_gnlPro.. (original name was: gnl|Prokka|GMEFPFMP_117)

Compact view
c00001_gnlPro.. - Region 1 - GR_AA_metabolism,Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 176,857 - 214,506 nt. (total: 37,650 nt) Show pHMM detection rules used
GR_AA_metabolism: (minimum(1, [Gly_430_pcre, Gly_8-9_TMA, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and not NRDD and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00001_gnlPro.. - Region 2 - PFOR_II_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 218,898 - 242,434 nt. (total: 23,537 nt) Show pHMM detection rules used
PFOR_II_pathway: cds(POR and POR_N and PFOR_II and EKR and Fer4_16 and TPP_enzyme_C)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00003_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 84,071 - 105,392 nt. (total: 21,322 nt) Show pHMM detection rules used
Region on contig edge.
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00004_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 24,159 - 49,170 nt. (total: 25,012 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00004_gnlPro.. - Region 2 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 62,803 - 88,122 nt. (total: 25,320 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00005_gnlPro.. - Region 1 - GR_eut-pdu-related
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 20,403 nt. (total: 20,403 nt) Show pHMM detection rules used
Region on contig edge.
GR_eut-pdu-related: (minimum(1, [Gly_430_pcre, Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1, PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2, [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not EutC and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00013_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 13,694 - 42,410 nt. (total: 28,717 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00017_gnlPro.. - Region 1 - Acetyl-CoA_pathway
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 28,002 - 56,986 nt. (total: 28,985 nt) Show pHMM detection rules used
Region on contig edge.
Acetyl-CoA_pathway: (CdhC and CdhD and minimum(8, [CbiA, FTCD_C, FTHFS, FeS, Fer2, GCV_H, MTHFR, MTHFR_C, Prismane, Pterin_bind, Pyr_redox_2, Pyr_redox_dim, RACo_C_ter, THF_DHG_CYH, THF_DHG_CYH_C]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00019_gnlPro.. - Region 1 - Others_HGD_unassigned,TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 23,062 - 54,510 nt. (total: 31,449 nt) Show pHMM detection rules used
Region on contig edge.
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00052_gnlPro.. - Region 1 - Others_HGD_unassigned
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 10,817 nt. (total: 10,817 nt) Show pHMM detection rules used
Region on contig edge.
Others_HGD_unassigned: (minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans, CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III, ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C, BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C, Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.