LOCUS       c00052_gnlPro..        10817 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GMEFPFMP_52.
ACCESSION   c00052_gnlPro..
VERSION     c00052_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 02:40:31
            Original ID  :: gnl|Prokka|GMEFPFMP_52
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10817
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..465
                     /locus_tag="ctg52_1"
                     /transl_table=11
                     /translation="RLLRIQLKDGSYENIATNLPRDEFKTEDFEMLYHLRWSEENSFRD
                     LKYSLCLKAFHSKKYAYIVQEVWARVILYNFSSSIIINVTIKREDCAYEYQANYSSALK
                     TCRDFLRIHDGTTKINVESLIAQNIEPIRPGRTFARQHRFKLPMSFCYRH"
     protocluster    1..10817
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[687:3631]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      688..3631
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10817
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10817
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(688..2367)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_2"
                     /sec_met_domain="HGD-D (E-value: 1.1e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 7.4e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(2360..3631)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg52_3"
                     /sec_met_domain="HGD-D (E-value: 2.3e-56, bitscore: 180.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERTFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             3875..5689
                     /locus_tag="ctg52_4"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNGYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDVNQIQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             5686..7452
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.7; E-value: 1.8e-86)"
                     /gene_kind="resistance"
                     /locus_tag="ctg52_5"
                     /transl_table=11
                     /translation="MSRLTIKDPAKSKSSETFLKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGTFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNFGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(7540..9327)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_6"
                     /sec_met_domain="Peptidase_M24 (E-value: 4.3e-43, bitscore:
                     136.5, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDGIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGENFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSARERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(9324..10172)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg52_7"
                     /sec_met_domain="ATP_bind_3 (E-value: 6.8e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLCEAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             complement(10659..10802)
                     /locus_tag="ctg52_8"
                     /transl_table=11
                     /translation="MHAIVWKIRVILLQTFVWIVDLKVREHLTEYLKKDIKYHRVTTGV
                     HV"
ORIGIN
        1 cgtttattgc gtatacagct taaggatggt tcttatgaaa atattgccac taatcttcca
       61 agggatgaat ttaaaacaga agatttcgaa atgctttatc atttgagatg gtctgaggaa
      121 aattctttcc gggatctgaa atattccctg tgtctgaaag catttcattc aaaaaaatat
      181 gcttatattg tacaggaagt atgggccaga gttattttat ataacttcag ttccagcata
      241 atcataaatg taacgatcaa gcgtgaagac tgtgcctatg aatatcaggc gaattattca
      301 tccgcactca aaacatgcag ggatttctta aggattcatg atgggacaac aaagataaat
      361 gtagaaagtc tgatcgctca aaatattgag ccgatcagac ctggaagaac ctttgcccgc
      421 cagcataggt ttaaacttcc gatgagtttt tgttatagac attaacattt agctcataca
      481 ttaactatat ttcattttca ggcaaatttc aatgttaaat attgattttg cctttttgtt
      541 gtacctaaaa ttcaataaga catcctatct tgttcgcatc ctacgctttt ttatcacatc
      601 caaatctttt tattaatatt tttcatcaaa gcaatgttgc caaatagctt aagttaatga
      661 cattggtagt gaacagtaac taaaaattta cacatcagcc atatcagccg caaacagtgc
      721 tgcgccaagt gcaccgcaaa gctgagcctt gtcactgatc accagctttg ttccaagctt
      781 ctcttccagt gtctttacca gacccttatt cttagaaaca ccaccggtca tcatatattt
      841 ctcctcaccg cccacacgtc tggtaagggc ggcagtcttt acggcaaccg ccttattcag
      901 gccatggaca atatcatctg ttgccttatt ctgggcgatc agtgatacaa cttctgattc
      961 tgcaaatact gtacacatac tggaaattgt aatatcttct ttgaattcca gcccacattc
     1021 gctcatctga tctagattca tttccatggt acgtgccatc atttccagaa atcgtccggt
     1081 tcctgccgca catttgtcat tcataacaaa gtttgcaact gcaccgttct catccagtcg
     1141 gatcaccttg ctgtcctgtc cgccaatatc aataacagta cggacttccg gattcaggaa
     1201 atgcgcaccc cttgcatgac aggtgatctc tgtgatactc ttatcaccat ttttaatagc
     1261 tgtacgtccg tatccggtag taaccagcgc atcaatatct tctctctgca atccggcctc
     1321 cttcaatgct tctgcaaggg cacggtctgc tccgatagca gctcctgctc ctgtaggcag
     1381 gataatgctg gtcacaatct catgatcttt atttaaaatc accacatctg tactggtgga
     1441 accactgtca atccctgcga aataaccttt tcccattttt ctctctcctt ttgtgtctcc
     1501 atctatggtc tgctccagtg tttcaggctg aatgctctct gcaaaagctt ccagtctggt
     1561 aagaagctga ccgctgctct gaatagtata atctgattca atttttaaaa gaggtacatc
     1621 tgtatggttc ttgatctcag catattcgaa gctgtaaaaa tcacaaaact tcactgtatg
     1681 ataaataatc cccgcaacag acggatcatt ataaagcttc ttacgacctg tcgggtccat
     1741 catacgcata catggaatct gccccagaat ctcacctgca taccagtcca tcagctcatc
     1801 aaaagaagca ccctccggtg gaagtatatt tcccacagaa cggttatgca cgcaggtatc
     1861 attctctaca ggaagaggca tagccttgct ggtcatttca aataattcct gccccattct
     1921 ggcgccaagc actgcaatat gggactttgt gattttctcc tgtgcatgga aagcagcccg
     1981 gaattttccg gcatcaaact ctgtgccttt gtactgtgca taagccttcg ccagcccttt
     2041 taactgtaca gccatacgct ctctgctaca ggcactgtca cagtgaagca catccaaaat
     2101 atagagaaaa tccagcttgc cgctttcaag cagaatgtca tagacactcc ggatagtatc
     2161 acagcagctc accaggacaa gttccttgat tttcccctcc atgactcctt ccagaagtgt
     2221 ttttccaaaa ccgcagatat tgggatgtga aacctgatcg gccaggtcaa atccctccgg
     2281 catatgatta aagttctcac attccccgcc aagagattcc agaagttcaa ttggggtata
     2341 tttacagaca tagtaagttt tattcattct cagcacctcc cagcatttcc agaaaagctc
     2401 ccagcctggt ggaagtctgt ccttctcctc catggcttcg atcacacccg tcaccgtcca
     2461 ggattaaaag gggcagaccg gcttcctcga acttcttctt tgcaagctgt gccgcaccaa
     2521 gcgtatgttt acatccccaa tgtccaaacc acacagcacc gtctgctcct gcctgtttcg
     2581 catggcggat accggcttca atccttctaa gggcacttcc gttcagtgaa tgatatacca
     2641 ttctttctgc cattgcttca aaggggttct caggatcaaa atccggctca caggtttctg
     2701 caagttcaca tcctacgatc tgggctttct cactgaagca aagctcctgg cgcactgcat
     2761 ccgaccagaa tggaatggta tgcatccagt aaatgtgttt ccctttcgct gccggtgctt
     2821 tcttaatatc ttcaagaagc atctgtgtat acttctcttc ttctgctgtt cccagaagga
     2881 tattgtttgt cattcctgca tacaagggtg tgaccagatc agagggcaca tatctgtctg
     2941 cacgcatctg ctgatatttt ttgtaattct ccagagtccg cttactgcag gcaagacgtt
     3001 cctttaatct gtcctcagag attgtttttc ctgtattttt ttccagaaat atttttaaat
     3061 cctttaactg atctgccaca tactgtacat tctctgtggt ctgattccat ggtacatcaa
     3121 tggcaaatac aggtacctgg taaaaatctg ccagggtacg gaaagtgagc aggttagcat
     3181 cgcaggtcag gttggtataa acaatacatt taggctttgg cagaagtcct ttctgcgctg
     3241 caccaagaaa tgtcttgtga taactgcaca gtgtctctgc aattccctga ttctctgcct
     3301 gctgcagaaa cgtcctctct gctttgcttg cagaaagata gcaggaaaat ccctctacat
     3361 tatagggatg taatcccacc tcctgcatca tttcgcaggg tgtaaaaata cttacaataa
     3421 cagaatcttc cggtttctga aggggccgca gcatggtatc catcatcaga tttgcaagat
     3481 gcctgtctgc aggcatcagt ctcttgtcct gcatgtaacg gaacttcaga ttctgcgcct
     3541 cccagccggt ttttaacagc cgtcgggctg actgaggctt tttatccgtc agattttcca
     3601 cataatgacc aaatgtctca ataatctcca tagtctgtct cttcctcatt atggtaataa
     3661 taatttatca gttgccagcg tacaaatagc gctacggaat attttagtaa tatctttttt
     3721 tgaagtcaag ctgaattttc tccaaagttc atctgttttt gcacattctt cttgacaaaa
     3781 aagtcttaaa tgatacactt ttgaatgtat tatttttcaa aaaaaggaag gaataatata
     3841 ggaaagattt ttacgaaagg aaggaatttt taaaatgcgt tcattgacgg tttatttaaa
     3901 aaactacaaa aaagaaagca tccttgcgcc attttttaaa tttctggagg ttgtatttga
     3961 cctgatcgta cctatcgtca ttgcacagat catagatgta ggtattgcaa accacgacaa
     4021 cggatacatt gtccagagat tttctattct tatactaatg gcggctcttg gtcttgccag
     4081 taccatcaca gctcagttct ttgccgctaa agccagcgtg ggctttgcca cagaattaag
     4141 acaggcagtt tatgaccatg tacagcatct gtcctataca gagttggata cactgggaac
     4201 agatactctt atcacaagac tcaccgatga tgtcaatcag attcagaacg gattaaatat
     4261 gggacttcgt cttcttcttc gaagtccgtt tatcgtactt gggtccatgg tcatggcatt
     4321 taccattgac tttaaatgtg ccctggtttt tgctgttgcg atcccgtttc tgtttctggt
     4381 tgtctttgtc attatgtttc tcagtattcc tctgtttaaa aaagtacagg gaaaactgga
     4441 cacagtaacc ggactgacca gagaaaacct tacaggcgtc cgcgttatcc gtgcattctg
     4501 ccgcgaaaaa gaggcagttg cagaatttga tacccgcaat caggagctga caaagttaaa
     4561 tctctttgta ggaaagcttt ccgctttgtt aaatccggtc acttacgtac tgatcaatat
     4621 tgctactgtt attctgatcc agaaagcagg agtagaagta aatcttggcg gtatgcagca
     4681 gggacaggtt gttgcccttt ataactatat ggctcagatg atcgtggaac tgatcaagct
     4741 tgcctccctg atcatcaccc tgaacaaatc tgcagcctgc gcaggacgtg tggcagatat
     4801 cctgaaagtg aaatctacta tggattaccc ctcttcctcc acatattctg ctcagatatc
     4861 gaaggacctt gcaacagcaa ctgctgatgc atcactttct gaaaatgcca tcgtattcaa
     4921 tgacgtaacc tttgagtaca gcaaagccgg tgcccccagt ctttcccata tcagtttttc
     4981 tgtaaaaaag ggacagaccg taggtattat cggtggtaca ggaagcggaa agaccactct
     5041 ggtaaatctg atttccagat tctatgatgc cagcaaagga actgttctgc tggatggtca
     5101 gaatattgaa aattacacca gaagtgatct ccgctccaga atcggcgttg ttccacagaa
     5161 ggcagctctt ttcaaaggct ctatccggga caatctgaaa tggggccggg aagatgcctc
     5221 tgacgaggat ctgtggcagg cacttaccac agcacaggga aaagaggtag tagagggtaa
     5281 accgggacag cttgatttta tgctggaaca gaacggtaaa aacctttccg gcggccagaa
     5341 acaaagactt accattgccc gtgccctggt aaaaaaacct gaaatcctga tcctggatga
     5401 cagtgccagt gccctggact ttgccactga tgcagcactg cgtaagtctc tcaacagact
     5461 tgactggaaa gtaactacat ttctggtatc ccagcgttcc tccagcattc agcaggcaga
     5521 cctgatcctt gtccttgata acggtactct ggcaggtaag ggtactcatg ctgaactgct
     5581 acgtacctgt gatacttacc gggaaatcta cttctctcag tttccggaag aaagagccag
     5641 atactcctct gtatctgcag gtaatataat gaaggaggtg actgtatgag cagattaaca
     5701 ataaaagatc ctgctaaaag caaaagcagc gaaacttttc ttaaagtact gcgtttcatc
     5761 ggaagatacc gttttctgct gatcctcagt atcatactgg cagcagtttc cgttatcctt
     5821 cagctgtatg tcccaatcct attcggaaat gccattgatc aggtcattgc ccaacatcag
     5881 gtaaacttcg aaatgatgtg gtattacctg tcacgtatcc ttgtaatggt catcctctct
     5941 tctgctgcca cgtggcttat gaatgtgatc aataaccgca tgacctacca gacagtaaag
     6001 gatatccgtg ccaaagccat ccgacacatt caggtacttc ccctctctta ccttgacgga
     6061 cacagtaccg gagatatcat cagccgtatt atcgcagata cagatattct atccgatggt
     6121 atgctgcttg gatttaccca gcttttttcc ggaatcgtaa cgatcatcgg aacactgatc
     6181 ttcatgttct ccaaaaattt ctggattaca ttgatggtca ttgtcctgac ccccgtaagc
     6241 tttttggtgg ccaaatttat ttcttcccat accttccaga tgttccggaa gcaaagcgat
     6301 gccagaggac gtcagactgc tctcatcgaa gagatgattg gaaaccagaa ggttgttcag
     6361 gcttttggat atgaggaaaa atcttctgaa cgctttgcaa aggttaacga agaattacag
     6421 gaatgcagtc tgaaggctgt tttttacagc agcctgacaa acccttccac ccgttttgtc
     6481 aataatgtta tttatgcctg tgttgcactg gtgggtacat tcattatccc tggaggcaga
     6541 ctgacagtcg gaggactttc cgtacttctc tcctatgcca accagtatat gaaaccattc
     6601 aatgatatca gttccgttgt tacagaactt cagaatgctc ttgcctgtgc aggcagaatc
     6661 ttcgatctgc tggaggagga accggaagtt gcagaggctt ctgagacact gaaagatgta
     6721 aagggtgaag tagatattaa gaatgtgtgc ttccattatg atgaatcaaa gaaactgatt
     6781 gaggacttta atctccatgt aaaaccaggt atgcgcgttg ccattgtagg acctaccgga
     6841 tgcggtaagt caacctttat caaccttctg atgagattct atgatgtaaa tttcggatct
     6901 atttccgttg acggcaaacc gatcagagac attacccgcc attctctcag aagcagctat
     6961 ggtatggtgc ttcaggaaac atggatcaaa aacggaactg tccgcgacaa tatctcgatt
     7021 ggaaaaccgg aagctacaga tactgaaatc atcgaagcag ccaagcttac ccacagctgg
     7081 gaatttatcc ggaggcttcc taaaggactg gacaccatgc tcaacgaaga cagcttaagc
     7141 cagggacaga aacagctgct gtgtatcaca cgagttatgc tctgtctgcc tccgatgctg
     7201 atcctggatg aagccacttc cagtattgat acacgaacag aattacaaat tcaggaagcg
     7261 tttgaacgaa tgatggaggg aagaacaagc tttatcgtag ctcacaggct ttcaaccatc
     7321 cgaaatgcag atctgattct tgttatgaaa gacggaagta tcattgagca gggtactcat
     7381 gatgagctga ttgcaaaagg tggattttac catactttat ataacagcca gtttgcaaaa
     7441 gtttctgaat aaaacaagcc agataataaa tcaaaaagga acagctgtcc atcacggctg
     7501 ttcctctttt tgattttgta aaatattttt ttatttttat cagattgctc gggtagcatc
     7561 tttcagccat tctttttctt cttcgttcaa atacggagaa atcttctcat atacctgtgc
     7621 atggtaatca ttgagaaggt tacgttcccg ggcactcatc agttccggca ccactccatc
     7681 cagatcaaaa ggtaccatag ttagaaattc aaaacacata aactgaccat actctgtttt
     7741 ttcagctttt ttgcagacca tcagattttc atgacggatt ccaaatccat cctctctgta
     7801 atatcccggc tcatcagagg tgatcattcc ctcctccagc actgcatttc cacccggaac
     7861 aattttccat cggaagctat tgggtccttc atggacattc agaagatatc ctactccatg
     7921 accggttcca tgtttaaaat tctctcccat ttcccatagc ggctgtctcg ccagaatatc
     7981 cagatttaca ccggtacagc catgaagaaa tctggcagct cccagattca gagttccccg
     8041 caaaactgct gtgaagtact ttttctcttc ctcagtagtc ggtcccatga caacagtacg
     8101 ggtaatatca gtagttccct ctttataatg tcctcctgta tctgccagaa gaaagccgga
     8161 tggttccaga ggaatatccg tttcgggtgt tgcaaaataa tgtacaatag cagcatgctt
     8221 tccataggca ataatcggat caaaactgtt atctatgaaa tcctcctgtt ccgaacggaa
     8281 ttcatacagc ttttctgctg cacttaattc tgtgatcgga atccttccaa cattcttctt
     8341 taaccagtat atgaactttg taactgcaac tccgtctctg atatgcgcaa tgcgttcatt
     8401 ttccacctca acaggattct tcgttgcctt gggaagaagt gtaagatttt cttcatccag
     8461 aatccgggtg tctgccggaa tattgctaac cagacgactg ttgactttct ttttgcagag
     8521 aagaactttt ttgtcctttt taaatgtttt cacatactca tagataccgt catagggaaa
     8581 aagggtcaca ccatcttttt ccagcgcttc cagtacgtct gtctgaaagg ctttctcatt
     8641 tgcaaaaagt ctgatctctg tttttgtcat tacaagataa gaaagaacca ccggacaaca
     8701 gtggatatct cccccacgta tatttaacag ccaggcaata tcatccagag aagtcagtac
     8761 aaataaatct gcacccttct tctccattgc tttgcggatt cttgcgcatt tatcagctct
     8821 ggattctcct gcccatttta tatccagctc tgtaaccggt tcacaggaaa gtaccggacg
     8881 gttttcccat atatcgcctg ccagatcgtg atcaacactg agagacacac cgttttcatc
     8941 cagcattttc tccaattctg ctgcctcttt tgcactgaca gtacgtccgt caaatcccag
     9001 acaccttccc tgtgtcagat tttttttcag aaattcatga actgtgggaa cttccggttc
     9061 acccatttta aataaagtaa ttcctgttcc ctccagctga tctgcagcct ggataaaata
     9121 acgtccatcc gtccataatc ctgccatatc ctgcatgatc accgcagtgc ctgcagaacc
     9181 ggtaaatcct gtgatatatt ttctgcattt gaaatattca cctacatatt ctgaaccatg
     9241 aaaatcatct gtaggaatca gatatgcatc aattcctgtt tctttcatgc gtgcacgaag
     9301 tgctgctatt ctctctttta ctgtcattcg tttttaccct taaggctgct atctgcagtc
     9361 gttttatcat tttcgccaag tgtttcgttc atacttccca tacgatatcc cagaatatcc
     9421 atggtcacat aagtgaatcc atactcctta aatttctttg caatatcctc tcggacattt
     9481 ttttccagaa gtttcggaaa ttcctccggc atgatctcaa ttcttgcaag tgaaccgtga
     9541 atacggacac gtacctgatg gaatccatag tcaagtaaaa gctgctctgc tttctcaacc
     9601 attccaagct tttcctcact gatggtctct ccatagacaa acctggagga cagacaggca
     9661 aatgactgtt tgtcccaagt cggaagcccc agttcctttg agtattctct gatctccgct
     9721 ttcgtcagct tcgcctcaca tagcgggctc ttaactccaa gttcttttac ggcgatcaga
     9781 cctggtctgt aatcgccgtt atcatccata tttgatccct ctgcaatata ttcaatccca
     9841 ttcttttttg caatatcgcc aatcttctca aacagttctt ttttacataa ataacatctg
     9901 ttcggaggat tctttgaaaa tccttcaatc tccaattcct cagactggca gatcacatgc
     9961 tgaatcccct ctttctcgca gaatgccttc gcttcattca gctctctttt cgggaaagaa
    10021 caggattgag ccgtaatcgc aatcgcctta tcacccagca catcatgagc tacttttaat
    10081 aagaatgtag aatccactcc acttgagaaa gcaactgcta cactgccaag tcccttcaga
    10141 tattctttta aatgttctag tttattttcc atatcagtct gcctcttgtc cgttttttat
    10201 tgtacctgta gcactcctcg taaataatgt atattgatct ggctcaacaa agcgtgaaag
    10261 ttgaactttc tcaaatgtat tatttaacag ggtgctatag cttcattata atataggcaa
    10321 cgactgttca gcaacctatt tttcgcattg cgaaatgtgt tactgaaaat agaacgaaca
    10381 atattgattt atgtttcttg tatcttttct aacgcttccc cgacttctat tacttcttta
    10441 aatagtttct aaagtaacag cctctcttaa cttctttatt tacagtttgt ctacttcttt
    10501 ttctgaagca gttctccgtt tgtttcttct ccattcatac atgacataat aattaaccac
    10561 taccccatat tataaataac acccagagat acttatttca gactgataat cagattttta
    10621 ttgaatttat taatctatat gttatgacaa catatctttc agacatgtac tccggtagtc
    10681 actcggtgat attttatatc tttctttaaa tactcggtta aatgttctct gactttcaaa
    10741 tccactatcc agacaaatgt ttgtaataga atcactcgta ttttccaaac gatggcatgc
    10801 atagttcagc cttacat
//
