LOCUS       c00067_gnlPro..        10904 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDHHLGGG_67.
ACCESSION   c00067_gnlPro..
VERSION     c00067_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:22:33
            Original ID  :: gnl|Prokka|IDHHLGGG_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10904
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10904
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1037:7950]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1038..7950
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..10904
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10904
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(115..798)
                     /locus_tag="ctg67_1"
                     /transl_table=11
                     /translation="VITYTYDAKDRLTGTRNSRDGVTETTTSDYVYDGKTVTYTEKTWA
                     GETLWNSQKFKRTYLDDALEKVLEERITDKDDHIIQRICNEYDQQERLVHSLEYSRGNS
                     KVSETKYTYDGKLVICDKYWLKNTGEVSAVSKYIITYSDDELTKPLIHGCLASEETAER
                     PWDWVRHYSYDYRGRLNGITYEAEGKLVWETRNYVYGNKSLTCENREVHYGTDIITISE
                     TTYKH"
     CDS             complement(1038..2162)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: MeaB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_2"
                     /sec_met_domain="MeaB (E-value: 1.6e-101, bitscore: 328.5,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFTRIDHYEKEYADTHHDTALNVTQGVEEQPIVSPYFKRRKKRA
                     LSTGEYVEGILAGNITTLSQAITLVESSNPDHYAQAQEIIEACLPHAGKSVRIGITGVP
                     GAGKSTFIEAIGNMVAGLRHKLAVLAIDPSSERSGGSILGDKTRMESICNNPSVFVRPS
                     PSAGSLGGVARKTRETIVLCEAAGFDVIFIETVGVGQSETAVHSMVDLFMLLQISGAGD
                     ELQGIKRGIMEMADLMVITKADGENIHKAELAQTQFQGALRLFPVPESGWRPKVYTSSA
                     VARTGLEEVWKGVEEYLDHIQKNGYFQHNRNRQNKYWMYESINEALRGSFYRDPAVEAC
                     IGAYEKRVLEDKISSFIAAKELLEIYFKDARTLE"
     CDS             complement(2169..2633)
                     /locus_tag="ctg67_3"
                     /transl_table=11
                     /translation="MKKVLLIWLLAAGFASAGATAQNIALGERVPELKIQTWLDNRQPE
                     PAPTTYIEFFHSTNPACKTSLERLKEITGKSGTKLRVIVVTKEDPAKIAPLLRPYLSER
                     ISVGLNAEKSFTAFGVSYLPFGVLTDAKNRTLWMGNSLQINEKLIEQSTR"
     CDS             2705..3694
                     /locus_tag="ctg67_4"
                     /transl_table=11
                     /translation="MKIGLDTAPAALRGTYFQHLASVLARYAPEHEYIIGAEVNDGVDL
                     YHGFRSSLPLSVHLRRVPSVMTVPNLNFLRYPHLYTFAERLFVLTLYRRALRRAGRVIT
                     VSAPAREELSERLNIDPSKIEVMVSLAVPAPRGNPSQAKLEHVRRKYALPEHFILMIGT
                     VEPRHNHQAVFAALADVASPAGVVVCGRRTAWSDYLLGYARARRIAARVDFIYELTPSD
                     LPALFRLARVFAYLPDADAEASVVPVVEALRAGLPMVLSDTQVNREAAGEAAAYVRPEA
                     RGEVLAALENALEDVSWRRTMQERERRRAELFSEYAVAERLMQIYTSL"
     CDS             3905..4315
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.4e-27, bitscore:
                     84.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVSHIEHLGVAVKSLDEAIPYWENVLGLKCYAIEEVADQKVRTA
                     FFMLGQTKIELLEPTSEDSTIAKYIENRGVGIHHMALACENIEEQLADAEAKGIRLIDK
                     TPRKGAEGMTIAFLHPKSTQGILTELCENKNK"
     CDS             4320..5885
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_6"
                     /sec_met_domain="CT_Btheta (E-value: 2.7e-286, bitscore:
                     939.4, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQIQEKINKLIENRETARLGGGQKAIDKQHDKGKYTARERIQML
                     LDEGSFEEFDMFVTHRCYDFGMDRKHTFGDGVVTGYGTIDGRLVYVFAQDFTVTAGSLS
                     LSMSDKICKVMDMAMRNGAPCIGMNDSGGARIQEGVNALAGYANIFQRNVMSSGVIPQI
                     SAIFGPCAGGAVYSPALTDFIIMKKETSNMFLTGPKVVKTVTGEDVTQEQLGGATMHTT
                     KSGVAQFAVDTEEEGIALIRKLISYMPQNNMEDAPLAVCTDKITRLEDSLNEIVPDSAN
                     KPYDMSEVIKAIVDNGEYLESAPGYAKNVITCFARFNGQSVGIVANQPKFMAGVLDINA
                     SRKAARFIRFCDAFNIPIVTLVDVPGFLPGTTQEYGGVITHGAKLLFAYCEATVPKVTV
                     TLRKAYGGAYIVMSSKHIRGDINYAWPTAEIAVMGASGAVEVLYGKELKELADKPEEKA
                     KFIAEKEQEYNDKFSNPYNAARYGYIDDVIEPRNTRFRVIRALQSLATKRLQNPAKKHS
                     NIPL"
     CDS             5916..6236
                     /locus_tag="ctg67_7"
                     /transl_table=11
                     /translation="MNWGWSEILWVSLIGFSLVFILLVALIFIMKAFGACFRVRPASGR
                     KVDAQPMISEEEIAAIATALKIYKGALHDRESEVLTILNIKRAYSPWNSKIHGLTQLPD
                     RR"
     CDS             6273..6734
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 71.2; E-value:
                     1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_8"
                     /sec_met_domain="Biotin_lipoyl (E-value: 3.3e-23, bitscore:
                     71.2, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYSLKINGHNYNVQIDDVNEASTVAHVVVNGVDYEVEIEGAKA
                     STVSKPQVSPAPKSANSAMITPSTATPSPRIAPAPSTSGSSVKCPLPGTVLSVKVAVGD
                     TVAAGQTLVVLEAMKMENNIDADRAGVVKQILVQQGATVMEGDVLIVIG"
     CDS             6739..7950
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_9"
                     /sec_met_domain="OAD_beta (E-value: 3.2e-169, bitscore:
                     552.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWNALTSSSNFVLESLETFAESTGVSGLIANMGWGSLIMICVAFF
                     LLYLAIKHKFEPLLLLTIAFGMLLTNLPGANLYHTELFAGGHVHWDIFVAQAGLLDYLY
                     LGVKLGIYPCLIFVGVGAMTDFGPLIANPKSFLLGAAAQLGIFLTFIGAYALGFSPAEA
                     GSIGIIGGADGPTSIYLTAILAPELLGPIAVAAYSYMALVPVIQPPIMRMLTTEKERKI
                     KMRQLRPVSKTEKILFPLIITVIIALLLPSAAPLVGCLMLGNLMKECGVVDRLSKTVQN
                     ELMNIVVIFLGLTVGATATAEAFLNPRTLFILVLGVIAFAMGTAGGVLLAKVMNFFSKG
                     DNKINPLIGSAGVSAVPMAARVSQTEGQKADPSNFLLMHAMGPNVAGVVGSAVAAGILL
                     SFLG"
     CDS             8089..9366
                     /locus_tag="ctg67_10"
                     /transl_table=11
                     /translation="MKRLFMVLFGLASLHAAATAAKTAGEEKTPGKNAGAAASLWPEKM
                     DPSFQGSRPECFKIWVIRNLRFPADRYDVGDEAKVEVVFAIDKNGTLTDLKVTHCEERH
                     FADRLCKTIALSPKWSPGRTKGKPVKTELEMRFVFRLVAPPAGQEELGLCAEECDIHTT
                     ADRMPLFCGGGPDGFRAWVQRQVDSLMGPGALTEPRKLILRFVVGKDGRVTPAPKPKYR
                     DEDALEQTVRQAIAAAPAWTPATIDGERVRFGVSMPVAFGPGAAGAEYSDKDAYRVVEV
                     MPKFFGGGLDKFRSWVMAEVRYPSDMLKRGVQGRVVAAFVVDKEGGLRWWRFSSRRIRN
                     FRKRSLVCLDVRRGGRRAGRTVRSSGWNTRCRSISKFARNCGSRAAPPAGTGVHPVRID
                     TAARLPPACQGRPVTPRSCFGMPQLS"
     CDS             9509..9964
                     /locus_tag="ctg67_11"
                     /transl_table=11
                     /translation="VDSLSYKTISANAATVTKEWVVIDATNEVLGRLASQIAKILRGKN
                     KPSYTPHVDCGDYVIVINAEKVKLTGNKMTEKVYTRHTGYPGGQRFATPADYLAKKPTF
                     IVEKAVKGMLPRTRLGAALLKNLKVYAGSEHPHAAQNPKTIKLNEIK"
     CDS             9970..10356
                     /locus_tag="ctg67_12"
                     /transl_table=11
                     /translation="MEVVNTVGRRKAAVARVYVKPGKGQITINRKALEVYFPLEILQYQ
                     VKQPLLATNTVENYDIAINLDGGGITGQASAARLGIARALCEIDAEMRPVLKKAGFLTR
                     DPREVERKKPGQPGARRKFQFSKR"
     CDS             10540..10902
                     /locus_tag="ctg67_13"
                     /transl_table=11
                     /translation="MSRTDFNTLLEAGAHFGHLKRKWNPKMAPYIFMEKNGIHIIDLHK
                     TVLKIDEAAAAIKQIAKSGRRVLFVATKKQAKDIVAEKVAAVGMPYVTERWAGGMLTNF
                     PTIRKAVKKMSTIDKMA"
ORIGIN
        1 ctaaatcatt acctcataaa aaagcaatgc cgtaactcat tcagttacag cattgctttg
       61 taaatccccg gaaactcccg cgagagggcg gggctgtttt gccggagatc ggtgtcagtg
      121 tttgtaggtt gtttcagata tggttataat atccgtgcca taatgcacct cccgattttc
      181 gcaagtgagg gatttgttcc catatacgta gttgcgggtc tcccagacga gcttaccttc
      241 cgcttcgtac gtaattccgt tgaggcgtcc ccggtaatcg taactgtaat gtcttaccca
      301 atcccatggg cgttcggccg tttcttcgga agccagacag ccgtgaataa gcggtttcgt
      361 cagttcatcg tcggagtatg tgattatgta tttgcttaca gccgatactt cgcctgtatt
      421 cttgagccaa tatttgtcac agattaccag ttttccgtcg taggtgtatt ttgtttcgga
      481 tactttacta ttccctctgg aatattccaa actgtggacc agccgttcct gctggtcgta
      541 ttcgttgcaa atccgttgga tgatatggtc gtccttgtcc gttatccgtt cttccaaaac
      601 cttttcgaga gcgtcatcca gataagtgcg tttgaatttt tgcgaattcc acagggtttc
      661 accggcccat gttttttccg tgtatgtcac cgttttgccg tcatatacgt agtccgaagt
      721 tgtcgtttcc gtaacgccgt ctctcgagtt ccgggttccg gtcagccgat cttttgcgtc
      781 gtaggtgtac gttatcacat atgtactcta ctctcctccg ggatcggttc tgtgaagggt
      841 cgttgtcagc gggtgtgtcc atttagagtc gcctgtgttc tctccgtcct ctttttcaca
      901 acctgaagcg agcagcaata tcgccgcagc caggtaaaag cgtccttgtt tcatggctcg
      961 aaattttaac gattataagg gctgtattat gggcatatcc acctgccggc aacccgcctg
     1021 ccggaccgtg acacgggtca ttccagcgtc cgggcgtcct tgaaatagat ctccagcaac
     1081 tccttggcgg cgatgaacga cgagattttg tcctccagca cgcgtttctc gtacgctccg
     1141 atgcacgcct ccacggccgg gtcgcggtag aaacttccgc gcagcgcctc gttgatcgac
     1201 tcgtacatcc agtatttgtt ctgccggttg cggttgtgct ggaaatagcc gtttttctga
     1261 atgtggtcga ggtactcctc cacgcctttc cagacctcct ccagccccgt ccgggccacc
     1321 gccgacgagg tgtagacctt gggccgccat cccgattcgg gcacggggaa aagtcgcaag
     1381 gccccctgaa actgggtctg tgccagttcg gccttgtgta tgttctctcc gtcggccttg
     1441 gtgatgacca tcaggtcggc catctccatg atgccgcgct tgatgccttg cagttcgtct
     1501 cccgcaccgg aaatctgcaa cagcatgaag aggtccacca tcgagtgcac ggcggtttcc
     1561 gactgtccga cgcccaccgt ttcgatgaag atgacgtcga atcccgcggc ctcgcacagc
     1621 acgatcgtct cgcgcgtctt tcgggccact ccgccgagcg atcccgccga gggcgagggc
     1681 ctcacgaaga ccgaaggatt gttgcagatg ctctccatgc gggttttgtc gccgagaatc
     1741 gagccgccgc tgcgctccga cgaagggtct atggccagca ccgccagctt gtggcgcagc
     1801 cccgcgacca tgttgccgat ggcctcgatg aaggtcgatt tgccggctcc cgggacgccc
     1861 gtgatgccta tgcggaccga tttcccggcg tgcgggaggc acgcttcgat gatctcctgc
     1921 gcctgtgcat agtggtcggg gttcgacgat tcgacgagcg tgatggcctg cgagagggtg
     1981 gtgatgttgc ccgcgagaat gccctcgacg tactctccgg tggagagcgc gcgcttcttg
     2041 cgccgcttga agtaagggct tactatcggt tgttcttcaa cgccttgcgt gacgttgagg
     2101 gctgtgtcgt gatgcgtgtc tgcgtactct ttttcgtaat ggtctatcct ggtgaacgac
     2161 atggtgtgtc agcgtgttga ttgttcgatc agtttttcgt tgatttgcag ggaattgccc
     2221 atccagaggg tgcggttctt ggcgtcggtc agcacgccga acggcaggta gctgacgccg
     2281 aacgccgtga aactcttttc ggcgttgagg cccacggaga tccgttccga gaggtagggg
     2341 cgcagcagcg gggctatttt cgcggggtcc tccttcgtca cgacgatcac gcgcagtttg
     2401 gtacccgatt tgcccgtgat ttccttcagg cgttcgagcg aggttttgca cgcgggattc
     2461 gtcgaatgga aaaattcgat gtaggtcgtc ggggccggtt cgggctggcg gttgtcgagc
     2521 cacgtctgga ttttgagttc gggaacgcgt tcgccgaggg cgatgttctg ggccgtggct
     2581 cccgcggatg cgaaacccgc ggccaacagc catataagca gcactttctt cataagagag
     2641 ccttgtttta ttcgataaag ataacaatta tttggcatat ggaccaattt tttagaatca
     2701 agttatgaaa ataggactcg acacggctcc cgccgcactc cgcgggactt acttccagca
     2761 cctcgccagc gtgctggcgc gctacgctcc ggagcatgaa tatatcattg gcgcagaggt
     2821 gaatgatggt gttgacctct accacggctt taggtcgtcg ctgccgttgt ccgtgcatct
     2881 gcggcgcgtg ccttcggtga tgacggtccc gaatctcaat ttcctgcgct atccgcatct
     2941 ctatacgttt gccgaacggc ttttcgtcct gacgctctac cgccgtgcgc tccggcgggc
     3001 gggccgggtc atcacggtca gcgctccggc ccgcgaggag ctgtcggaac gcctcaatat
     3061 cgacccttcg aagatcgagg tcatggtgtc gctggcggtt ccggctccgc gcggaaatcc
     3121 atctcaagcg aaacttgaac atgtgcgccg caagtatgct cttccagagc attttatatt
     3181 gatgataggg accgtcgagc cgcggcacaa ccaccaggcg gttttcgcgg ctctggccga
     3241 cgttgcgtcc ccggccgggg tggtcgtctg cggccgccgc acggcctggt ccgactatct
     3301 gctgggctat gcccgcgccc gccgcatcgc cgcacgggtg gatttcatct acgaactgac
     3361 cccttcggac cttccggcgc tgttccgtct ggcgcgggtc ttcgcctatc tgcccgacgc
     3421 cgatgccgag gcgtcggtcg tccccgtggt cgaggccctg cgggcgggtc tgccgatggt
     3481 cttgagcgac acgcaggtca accgcgaagc cgccggagaa gccgccgcct atgtgcgtcc
     3541 ggaggcgcgg ggcgaggttc tcgcggcgct cgaaaacgcg ttggaagacg tgtcgtggcg
     3601 ccgcacgatg caggagcgcg aacgccgccg cgccgaacta ttctccgaat acgccgtggc
     3661 ggaacggctg atgcagattt acacgtcgct gtaaccccgg ctttcgaacc gcaggccgcc
     3721 ggaggctccg ccggaacgaa tcgcctttcc ggacatttcc tgcgaattcc gaacccgaag
     3781 ttattgccaa aaaaagtact ccgaattttg gcggttctga aagattcgtc tatctttgtg
     3841 ttcgcaaaat aacaacgaac gaaacaacat acgaatatcc actaacttaa atttaaattt
     3901 tgctatgaaa gtttctcata tcgagcatct tggcgttgcc gtgaagagtc tcgacgaggc
     3961 gattccctac tgggagaacg tattgggtct gaagtgctat gccatcgagg aggtcgccga
     4021 ccagaaggtc cgcacggcgt tcttcatgct ggggcagacc aagatcgaat tgctggagcc
     4081 gacttcggag gattcgacga tcgcaaagta catcgagaac cgcggcgtcg gcattcacca
     4141 catggcgctg gcctgcgaaa acatcgagga gcagctcgcc gacgcggagg ccaagggcat
     4201 ccgtctgatc gacaagaccc cccgcaaggg cgccgagggc atgaccatcg ccttcctgca
     4261 cccgaaatcg acccagggca ttctgacgga gctttgcgaa aacaaaaaca aataggatta
     4321 tgagccagat acaggaaaag atcaacaaac tgatcgagaa ccgcgaaacc gcgcgtctcg
     4381 gcggcggcca gaaggcgatc gacaaacagc acgataaggg caagtacacg gcccgcgagc
     4441 gtattcagat gctcctcgac gaaggttcgt tcgaggagtt cgatatgttt gtgacccacc
     4501 gctgctacga tttcggcatg gatcgcaagc acaccttcgg cgacggcgtg gtgacgggtt
     4561 acggcacgat cgacggacgt ctggtctatg tcttcgcaca ggatttcacc gtgacggccg
     4621 gttcgctgtc gctgtcgatg tccgacaaga tctgcaaggt gatggacatg gccatgcgca
     4681 acggcgcgcc ctgcatcggc atgaacgact cgggcggcgc gcgtatccag gagggcgtca
     4741 acgccctggc cggttacgcc aacatcttcc agcgcaacgt gatgtcgtcg ggcgtcattc
     4801 cgcagatttc ggccatcttc ggcccctgcg caggcggtgc ggtctattcg cccgcgctga
     4861 ccgacttcat cattatgaag aaggagacct cgaacatgtt cctcaccggc ccgaaggtcg
     4921 tgaagaccgt gacgggcgag gacgtgacgc aggagcagct gggcggcgcc acgatgcaca
     4981 ccaccaaatc gggcgtggcg cagttcgccg tagataccga ggaggagggc atcgcgctga
     5041 tccgcaagct catttcctat atgccgcaga acaacatgga ggacgctccg ctggcggtct
     5101 gcaccgacaa gatcacccgt ctggaggatt cgctcaacga gatcgttcct gacagcgcca
     5161 acaagcccta cgacatgtcg gaggtcatca aggcgatcgt cgacaacggc gagtatctgg
     5221 agtcggctcc cggctatgcc aagaacgtca tcacctgctt cgcccgtttc aacggccaga
     5281 gcgtgggcat cgtcgccaac cagcccaagt tcatggccgg cgtgctcgat atcaatgcca
     5341 gccgcaaggc tgcgcgcttc atccgcttct gcgacgcgtt caacattccg atcgtgaccc
     5401 tcgtggatgt tccgggcttc ctgccgggta cgacgcagga gtacggcggc gtcatcaccc
     5461 acggcgcgaa actgctcttc gcatactgcg aggctacggt gcccaaggtt accgttacgc
     5521 tgcgcaaggc ttacggcggc gcctatatcg tgatgtcgtc gaagcatatc cgcggtgaca
     5581 tcaactacgc atggccgacg gccgagatcg ccgtgatggg cgccagcggc gccgtcgagg
     5641 tgctctacgg caaggagctg aaggagctgg ccgacaaacc ggaggagaag gcgaagttca
     5701 tcgccgagaa ggagcaggag tacaacgaca agttctccaa cccctacaac gccgcacgct
     5761 acggctatat cgacgacgtg atcgagccgc gcaacacgcg tttccgtgtg atccgcgcct
     5821 tgcagtcgct ggctacgaag cgtttgcaga accccgcgaa gaaacattcg aacattcctc
     5881 tctaacagac tgaaaagatg acaatactga cagttatgaa ctggggatgg tccgagatac
     5941 tctgggtgtc gctgatcggg ttcagcctgg tgtttatcct gctagtggcg ctgatcttca
     6001 ttatgaaggc cttcggggcc tgcttccggg tccgcccggc gagcggcagg aaggtcgacg
     6061 cccagccgat gatcagcgag gaggagatcg cagccatcgc tacggcgctc aagatctaca
     6121 agggcgccct gcacgaccgc gagtccgagg tgctgaccat tctcaacatc aagcgggcct
     6181 attcgccctg gaattcgaaa attcacggtt taacccagct tcccgaccgg agataggacc
     6241 ctgcgtcgga acaagacaac ccaaaaaaga aaatgaaaga ttactctttg aaaatcaacg
     6301 gacataatta caacgtccag atcgacgacg tgaacgaggc ctcgacggta gcgcacgtcg
     6361 tggtcaacgg cgtggattac gaagtcgaga tcgagggcgc gaaagcctcg acggtctcca
     6421 aaccccaggt gtccccggcc cccaagtcgg ccaacagcgc catgatcact ccctcgacgg
     6481 ccactccttc gccgcgcatc gctcccgcgc cttcgacgtc gggttccagc gtgaaatgcc
     6541 cgctgccggg caccgtgttg agcgtgaagg tggctgtggg cgataccgtc gcggcaggac
     6601 agacgctcgt cgtgctcgaa gccatgaaga tggagaacaa catcgacgcc gaccgcgccg
     6661 gtgtcgtgaa gcagattctc gtgcagcagg gcgctacggt catggaaggc gacgttttaa
     6721 tcgtaatcgg gtaggactat gtggaatgca ttgacttcca gctccaattt cgtgctggaa
     6781 agccttgaaa cctttgccga atcgacgggc gtgtccggtc tgatagccaa catggggtgg
     6841 ggcagtctga ttatgatctg tgtggccttc tttctgctgt acctggccat caaacataag
     6901 ttcgaaccgc tgctgctgct gaccatcgcg ttcggcatgc tgctgacgaa ccttcccgga
     6961 gcgaacctct accatacgga actttttgcc ggggggcacg tccactggga tattttcgtc
     7021 gcccaggcgg gactcctcga ttacctctat ctgggcgtga agctcggcat ctatccctgc
     7081 cttatcttcg tgggcgtggg cgccatgacc gacttcggcc cgctgatcgc caaccccaag
     7141 agcttcctgc tgggagccgc ggcgcagctt ggtattttcc tcacgttcat cggcgcttat
     7201 gcgctcggat tctcgccagc cgaggccggt tcgatcggca tcatcggcgg cgccgacggt
     7261 cccacgtcga tctacctgac cgcgattctg gctcccgagc tgctcggccc gatcgccgtg
     7321 gccgcctact cctacatggc cctcgtgcct gtgatccagc cgccgatcat gcgcatgctg
     7381 accaccgaga aggagcgtaa gatcaagatg cgccagctgc gtccggtgtc gaagaccgag
     7441 aagatcctct tcccgctgat catcaccgtg atcatcgcgc tgctgctgcc gtcggccgct
     7501 ccgctcgtcg gctgtctcat gctgggcaac ctgatgaagg agtgcggcgt ggtggaccgt
     7561 ctgtcgaaga cggtgcagaa cgaactgatg aacattgtcg tcatcttcct gggtctcacg
     7621 gtgggagcta cggctacggc cgaggcgttc ctcaatccgc ggacgctgtt catcctcgtg
     7681 ctgggcgtga tcgccttcgc gatgggaacc gccggcggcg tgctgctcgc caaggtgatg
     7741 aacttcttct cgaagggcga caacaagatc aatccgctga tcggttcggc cggcgtttcg
     7801 gccgtcccga tggccgcccg cgtgtcgcag accgagggcc agaaggccga tccctcgaac
     7861 ttcctgctga tgcacgccat gggtcccaac gtggccggcg tggtcggttc ggcggtcgcc
     7921 gcgggcattc tgctttcgtt cctcggatag ggaatcgcgt tccgggccgc acggcccgat
     7981 acggttgcaa gagggtttcg gttcgccgga ccctcttttt tgcgcctgtg ccgttgcaag
     8041 tctcgcattt ttcgctatat ttatgaaacc taaaactcct gccttattat gaaacgcttg
     8101 tttatggtgc ttttcggcct tgcgtcgctg catgcggctg cgaccgccgc gaaaaccgcc
     8161 ggagaggaaa agacccccgg aaaaaacgcc ggtgcggcgg ccagcctttg gcccgaaaag
     8221 atggacccct cttttcaggg aagccgtccg gaatgcttca aaatctgggt gatccgcaac
     8281 ctgcggtttc cggccgatcg ctacgatgtc ggggatgagg cgaaggttga agttgtgttc
     8341 gccatcgaca aaaacgggac gctgaccgat ctgaaggtca cgcattgcga ggagcggcat
     8401 tttgccgacc ggctctgcaa gacgatcgcc ctgtcgccga aatggtcgcc cggacggacg
     8461 aaggggaaac ctgtaaaaac ggagctggag atgcgattcg tcttccggct ggtcgcccct
     8521 cctgcgggac aggaggagct ggggctttgc gccgaggagt gcgacatcca tacgacggcc
     8581 gataggatgc ccctgttctg cggcggcggt ccggacgggt ttcgtgcgtg ggtgcagcgg
     8641 caggtcgaca gtctgatggg tccgggtgcg ctcacggagc cgcggaaact gatcctgcgg
     8701 tttgtcgtcg gaaaggacgg gcgggtgact cctgccccca aaccgaaata ccgggacgag
     8761 gatgctttgg aacagacggt gcgtcaggcc attgccgcgg ctcctgcgtg gactccggcg
     8821 acgattgacg gagagcgggt tcgtttcggg gtctcgatgc cggtagcctt cggtcccggg
     8881 gccgccggag cggaatacag cgataaagac gcttaccggg tggtcgaggt catgccgaag
     8941 ttcttcggag gcgggctgga taaattccgg agttgggtga tggctgaagt gaggtacccg
     9001 tcggacatgc tgaaacgggg tgtgcagggg cgtgtggtcg cggcattcgt cgtcgacaag
     9061 gagggcggat tacgatggtg gagattctcg agtcgccgca tccgcaattt tcggaagcgg
     9121 tcgctcgtgt gcttggacgt gcgccgcggt ggacgccggg caggcaggac ggtgcgctcg
     9181 tccgggtgga atacacgctg ccggtcgatt tcaaaattcg ctcggaactg cggttcccga
     9241 gcggcgccgc cggccggaac cggggttcat cccgttcgta ttgacacagc cgcccgcctg
     9301 ccgcctgcct gccaagggcg cccggtaacg ccgcgctcct gcttcggaat gccgcaactc
     9361 tcctgaatac ggggccgttg cggttttttt gcgcggtttt cgattttgat tttcatttgt
     9421 ttttgcagat cagaaacttt ttcgtacctt tgcgcacccg caatgtgcgg ggaacggatt
     9481 acaataagtt aaattaaacg taaaaacagt ggattcatta agctacaaga ctatctcggc
     9541 gaacgctgcg accgtcacca aggaatgggt ggtgatcgac gctacgaacg aggtattggg
     9601 acgtcttgca tcgcagatcg cgaagatcct ccgaggcaag aacaagccca gctacacgcc
     9661 ccacgtggat tgcggtgact acgtcatcgt catcaatgcg gagaaggtga agctcacggg
     9721 caacaagatg accgagaagg tctacacgcg tcacaccgga tatcccggcg gccagcgttt
     9781 cgctaccccg gccgactatc tggcaaagaa accgacgttc atcgtcgaaa aagcagtcaa
     9841 gggcatgctg ccccgcaccc gtctgggcgc cgccctgctc aaaaacctga aggtatacgc
     9901 cggctcggag catccgcacg ccgcgcagaa cccgaagacc attaaattaa acgagattaa
     9961 gtaagagtta tggaagttgt aaacaccgta ggtcgtcgta aggccgctgt ggctcgcgta
    10021 tacgtgaagc cgggtaaggg tcagattaca atcaaccgca aagcgcttga agtttacttc
    10081 ccgctcgaaa ttctccagta tcaggtgaag cagccgctgc tggctaccaa caccgtggag
    10141 aattacgaca tcgccatcaa cctcgatggc ggaggtatca cgggacaggc ttcggccgct
    10201 cgcttgggca tcgcacgcgc attgtgcgaa atcgacgccg agatgcgtcc ggtactgaag
    10261 aaggccggat tcctcacgcg cgatccccgc gaggttgagc gtaagaagcc cggtcagccc
    10321 ggagcacgcc gcaagttcca gttcagcaag cgttaatccg aacgacctat tttcggcagg
    10381 cacggcgagg gttacaaacc ggaacgacta cctatatatt atatatatcg cgtattacct
    10441 tcaggttgcc ccgccgcgga aaatccgcgg gaccggcaag gccgctaccc gccggattga
    10501 agaaaagaga attaaaatta ttaaacacat tgaattaaaa tgtcacgtac agattttaat
    10561 acattactgg aagccggtgc gcacttcggt cacctgaagc gcaaatggaa ccctaaaatg
    10621 gctccttaca tcttcatgga gaagaacggc atccacatca tcgacctgca caaaaccgtc
    10681 ctgaagatcg atgaggctgc tgcggccatc aagcagatcg ccaagagcgg tcgccgcgtg
    10741 ctgttcgtag cgaccaagaa acaggccaag gacattgttg ccgaaaaggt ggcagccgtc
    10801 ggtatgcctt acgtcaccga gcgttgggcc ggcggtatgc tgacaaactt ccccaccata
    10861 cgtaaagccg tcaagaaaat gtccaccatc gacaagatgg cgac
//
