LOCUS       c00057_gnlPro..        10455 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NODMDCJF_57.
ACCESSION   c00057_gnlPro..
VERSION     c00057_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:09:53
            Original ID  :: gnl|Prokka|NODMDCJF_57
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10455
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10455
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:10455]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..10455
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10455
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10455
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             3..2618
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_1"
                     /sec_met_domain="HGD-D (E-value: 5.2e-16, bitscore: 48.1,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 1.6e-39, bitscore:
                     124.8, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FLTNGTEVRMNGSCAGGTGAFIDQMATLLKMSAEEMNKAAEQAQR
                     TYTIASRCGVFAKSDVQPLINQGARTEDIAASIYKAVVNQTIAGLAQGRPIKGNILYLG
                     GPLTFSTVLRKSFDEALNVTGTCPENSLLYVALGAALYADKEFVLTEVAAALDKYAATA
                     TYASEPPLFASKEEYEAFHARHMSHSVPRVAFSAHCGPVHIGIDSGSTTVKLVVVDEKS
                     QILYTNYQPNLGNPLPLIREQLLKIYKEHPGLQVASVTTTGYGEELVKNAFRCDYGLVE
                     TVAHFTAAKYFMPDVDFIIDIGGQDMKCFKIEDGAISNIFLNEACSSGCGSFLQTFAQA
                     LGYDVKEFAALGLFADRPVDLGSRCTVFMNSSVKQAQKDGASIENISAGLSISVVKNAL
                     YKVIRASSPEELGRKIVVQGGTFYNEAVLRAFEKEMGVEVIRPDIAGLMGAYGAALYGL
                     RQSHKNNQTTSAMMDEQELEKFAQQVVSVKCGGCGNHCQLTVNTFADGRKFISGNRCDK
                     PVTGKSEDNSLNLYAYKQQLLASYKPVPGKRGSIGIPLCLGFYELLPFWYAFWTSLGFA
                     VHTSPVSTRGLYLAGQATIPSDTACFPAKLSHGHIKALSQMQLDAIFYPCLTYNVDEGL
                     GDNHYNCPVVAYYPEVLAGNCPELEGKKFIYDYVGIHRPKDFVHKMAKEVLPKYFGGIS
                     EREVQAAADAAYAEYEAHMAKIRVKGSEIIDEARRQGKRIIVLAGRPYHVDPEVNHGID
                     HLITRHGAAVVTEDSISNRVQKFPTSVLNQWTYHSRLYAAAKYCTTQKDMDLVQLVSFG
                     CGVDAITTDETREILQRGNKLYTQLKIDEITNLGAVNIRLRSLFAALDERDEAAAEKSE
                     "
     CDS             2710..4026
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_2"
                     /sec_met_domain="HGD-D (E-value: 2e-22, bitscore: 69.2,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYHYPKFTPEMKKTHTILIPNMAVTQFRLMEYALRCEGYKCELL
                     GNCGSAVAQLGLKYVHNDTCYPALLVIGQFLDALNSGKYDLEHTALLITQTGGGCRASN
                     YIHLLRKALVKAGYPQIPVASLNFSGLEKDSGFQMTLPLARKCIACIFYGDMLCALRNQ
                     VAPYENEKGAADRMVDRWIARLGRALLAGKGFTSREMKHTFPLIAKDFAAIPVTRVPKV
                     KVGVVGEIYVKYSPLGNNDLQKFLESQDCEVNFPGLMGFVQYCAFNMGEDHVLYGGKLA
                     VKVGTDQFLNWLDSVERVMLKAETDAGFYAPGPFKELVEKPKGVISLGAKMGEGWLLTA
                     EMIELVQGGYGNIVCAQPFGCLPNHIVGKGMVNKIRALYPSANITPIDYDPSATRVNQE
                     NRIKLMLAVAKERLNAPVETQPLTAEQLAGGAPQVGATV"
     CDS             4301..5206
                     /locus_tag="ctg57_3"
                     /transl_table=11
                     /translation="MEKPAAACYHLPGLFEFYELYRRFLPLYREHREYFYDWCAIGSIY
                     GAPAGCIWGGGRISCGGAAAREVLALLREYGISGRLTFSNSLLRAEHLADPQCNALCEK
                     FAKAGSVPNGVIVHSDLLADYLQQRWPELYLVSSTTKVLTDFAQLRQELEKPQFRYVVP
                     DFRLNPALEQLRTLPSEQKAKVEFLCNECCWFGCTERKRCYETVSRQNLGEDCPDHRCA
                     APDAAGGYRFSKAMRSPGFIGVEDIRQRYLPAGFSHFKIEGRGLGSALVLEFLLYYMTK
                     PEYQLQVRETIYLDNMLDLF"
     CDS             5364..7946
                     /locus_tag="ctg57_4"
                     /transl_table=11
                     /translation="METTQKQIVLGILAHVDSGKTTLSEAMLYRAGAIRKLGRVDHGDA
                     FLDTDSLEKARGITIFSKQALLTAGNTAITLLDTPGHVDFSTETERTLQVLDYAVLVVS
                     GTDGVQSHTETLWRLLRRYHVPTFVFVNKMDLPGMTREQLLTQLNHRLGEGFVDFGAEP
                     AARNEALALCDEQLMEKMLDAGTLTDADIIPAVARRHVFPCWFGAALRLDGVDALLDGL
                     DRCTRAAPALHAFGARVFKVSQDEQGTRLTWLRVTGGELKVKALLSGEADGESWAEKAN
                     QLRLYSGAKYTLTEVIGPGQVCAVTGLTHAKPGTGLGAERDSDVPVLEPVLSYQVLLPE
                     GADVHAALGKLHRLEEEEPQLHVVWNESLGEIHVQLMGEVQLEVLRSLLAERFGLEVSF
                     GPGGILYKETITEPMEGVGHYEPLRHYAEVHLLLEPLPRGSGMQFAADCREEVLDKNWQ
                     RLVLTHLEEKQHLGVLIGAPLTDIKITLLTGKAHLKHTEGGDFRQATYRAVRQGLMLAK
                     SQLLEPWYAFRLEVPVENIGRAMSDIQRMEGSFDPPESGAETATLTGFAPVSTMRSYPM
                     EVVSYTRGRGRLSLTMDGYRPCHNAQEVIAEIGYQPEHDLENPADSVFCAHGAGFVVPW
                     SEVRSHMHVESGWGKAKPARPETQAVPQRRAMAYRATLEEDAEPLKIFERTYGPIKRDP
                     LAAFRPVQKTERPDFAAEQWEIAPEYLLVDGYNIIFAWDELNALAKESLDTARHRLMDI
                     LCNYQGYQKCVLILVFDAYRVPGSPGAIEQYHNIHVVYTKEAETADMFIERVTHEIGKS
                     RRVRVATSDGMEQVIILGHGALRVSARMFHEEVQNVEKQIRALVQGQA"
     CDS             8071..8958
                     /locus_tag="ctg57_5"
                     /transl_table=11
                     /translation="MAVEITEEFVWQSIPPRARDSHKGTFGSVLAVAGSAFYRGAALLA
                     AEGALRTGAGIVTLASVEPVVSAAVTRLPECCLCPCKEGAQGGIAPENVPLLRRQKATV
                     LLLGPGLGGTAQSAARAAETRTLVQQLLPGFAGAAVLDADGLNAAAQLLAEGKPFPHPA
                     GELVVTPHPGEMARLTGFSAAELAADREGIALHYAKAWNAVVVLKGAHTVVASPDGRVC
                     VNPTGNPGLARGGSGDVLAGMLAALLACGLPAYEAAACAVYLHGAAADRAAAKRGEYGM
                     LPHDILPELGELFA"
     CDS             complement(9252..9986)
                     /locus_tag="ctg57_6"
                     /transl_table=11
                     /translation="MTERNPILQSLFDRKSVRVYEEKPIPAEMKQAILEAAAQAPSAGC
                     QQLYTILDITDPALKEALAESCDHQPFIAKAPLVLVFCADCKKWYDAYLEAGCTPRTPG
                     VGDLMLAVTDAAIAAQNAVVAAESFGIGSCYIGDIMENCDTQRSLLHLPDYVFPAVMLV
                     FGWPTQQQKDRVKPQRCAMEHIVHENGYRTMDGAELRDTFGYKAGNAPFDQWCTAFCNR
                     KYNSDFSKEMTRSVEEYLSQFR"
     CDS             complement(10009..10455)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: Peptidase_M22"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg57_7"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.3e-30, bitscore:
                     95.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KTGDPKAYRLPVPHVEGKYNVSFSGLKTAVLNEVNKAQMKGEEVN
                     VPDLAASFQERIAGILAEKLLLAAADTGAKQVCLAGGVAANGRLRQLVNDGAQKLGAKV
                     YLPELKFCGDNGAMIAAQGYYQYIAGHTAGLELNGLPTLPIDYE"
ORIGIN
        1 tgtttctgac caacggcacc gaggtgcgca tgaacggcag ctgtgccggc ggcaccggtg
       61 ctttcatcga ccagatggcc actctgctga agatgagcgc cgaggaaatg aacaaggctg
      121 ccgagcaggc gcagcgcacc tataccatcg cttcccgctg cggcgtgttt gcaaaaagtg
      181 acgtgcagcc gctgatcaat cagggcgccc gcaccgagga tatcgccgcc agcatctata
      241 aggcagtggt caaccagacc attgccggtc tggcacaggg tcgccccatc aagggcaata
      301 tcctttatct gggcggcccg ctcaccttca gcaccgtgct gcgcaagagc tttgacgaag
      361 cgctgaacgt gaccggcacc tgcccggaaa acagcctgct gtatgtggcg ctgggcgctg
      421 cgttgtatgc cgacaaggag tttgtgctca ccgaggtggc cgctgcgctg gacaagtacg
      481 ccgccaccgc aacctatgcc agcgagccgc cgctgttcgc cagcaaggag gagtacgagg
      541 ctttccacgc acggcacatg tcccacagtg tgccccgcgt ggcttttagt gcccactgcg
      601 ggccggtgca tatcggcatc gactccggtt ctaccaccgt caagctggtg gtggtggacg
      661 aaaagagcca gattttgtac accaactatc agcccaacct tggtaacccg ctgcccctca
      721 tccgagagca gctgctcaag atttacaagg agcacccggg gctgcaggtg gccagcgtca
      781 ccaccaccgg ctacggcgag gagctggtaa agaacgcttt ccgctgtgat tacggtctgg
      841 tggaaacggt ggcgcatttt accgctgcca agtactttat gccggacgtg gacttcatca
      901 ttgatatcgg cgggcaggac atgaagtgct tcaagatcga ggacggcgcc atcagcaaca
      961 tcttcctgaa cgaggcctgc tcctccggct gcggcagctt tttgcagacc tttgcgcagg
     1021 cgctgggcta cgacgtcaag gagtttgccg cgctgggtct gttcgcagac cgcccggtgg
     1081 acttgggcag ccgctgcact gtgttcatga acagctcggt caagcaggcg caaaaggacg
     1141 gtgccagcat cgagaatatc tccgcaggcc tgtccatcag cgtggtcaag aacgcgctgt
     1201 acaaggtgat ccgcgcttcc agcccggaag agctgggccg caagatcgtg gtgcagggcg
     1261 gtaccttcta taatgaagcc gtgctccgcg cctttgaaaa agagatgggc gtggaggtca
     1321 tccggccgga cattgccgga ttgatgggcg cttacggcgc tgccttgtac ggcctgcgcc
     1381 agagccataa aaacaaccag accacctctg ccatgatgga cgagcaggaa ctggaaaaat
     1441 ttgcacagca ggtggtcagc gtcaagtgcg gcggctgcgg caaccattgc cagctgaccg
     1501 tcaacacctt tgccgatggc cgcaagttca tctccggcaa ccgctgcgat aagcccgtta
     1561 ccggcaaaag cgaggataac agcctgaacc tgtacgccta caagcagcag ctgctggcca
     1621 gctacaagcc tgtgcccggc aagcgcggct ctatcggcat cccgctgtgt ctgggcttct
     1681 acgagctgct gcccttctgg tacgccttct ggacgagcct tggctttgcg gtgcacacca
     1741 gcccggtgtc cacccgcggg ttgtatctgg ccggacaggc caccatcccc agcgataccg
     1801 cctgcttccc ggcaaagctg agccacggcc acatcaaggc gctgagccag atgcagctgg
     1861 acgccatctt ctacccctgc ctgacctaca atgtggacga gggcttgggc gacaaccact
     1921 ataactgccc ggtggtggcc tactacccgg aggttctggc aggcaactgc ccggagctgg
     1981 aaggtaaaaa gttcatctat gattatgtgg gcatccaccg tcccaaggat tttgtgcaca
     2041 agatggcaaa ggaggtgctg cccaagtact ttggcggcat ctccgagcgg gaggtgcagg
     2101 ccgcagccga tgccgcctac gcggagtacg aagcgcacat ggcaaagatc cgggtaaagg
     2161 gcagtgagat cattgacgag gcgcgccgtc agggtaagcg cattattgtg ctggcaggcc
     2221 gcccctacca tgtagacccg gaggtcaacc acggcatcga ccacctgatc acccgccacg
     2281 gggctgcggt ggttaccgag gacagcatct ccaaccgggt gcagaagttc cccaccagtg
     2341 tgctgaacca gtggacctac cacagccgcc tgtatgctgc cgccaagtac tgcaccaccc
     2401 aaaaggatat ggatctggtg cagctggtgt ccttcggctg tggcgtggat gccattacca
     2461 ccgacgagac ccgcgagatt ttgcagcggg gcaacaagct gtacacccag ttgaagatcg
     2521 acgagatcac gaacctcggt gccgtgaaca tccgtctgcg cagcctgttt gccgcactgg
     2581 acgagcggga cgaggccgcc gcagaaaagt cagaataaaa gaaaccctga gataggctga
     2641 agggcttccc cccggcgagg ggaagctttt gcggggacta tcttgtttag agcaacatag
     2701 gaggaaccta tggaatatca ttatcccaaa tttaccccgg agatgaaaaa gacccacacc
     2761 atcctcatcc ccaacatggc cgttacccag ttccggctta tggagtacgc actgcgctgc
     2821 gagggctaca agtgtgagct gctgggcaac tgcggcagtg ccgtggcaca gctggggctg
     2881 aagtatgtcc acaacgatac ctgctacccg gcgctgctgg tcatcggcca gtttctggat
     2941 gcgctgaaca gcggcaagta tgatctggaa cataccgcgc tgctgatcac ccagaccggc
     3001 ggcggctgcc gtgcctccaa ctacatccat ctgctgcgca aggcgctggt caaggccggt
     3061 tacccgcaga tcccagtggc aagcctgaac ttttccggtc tggaaaagga cagcggcttc
     3121 cagatgaccc tcccgttggc acgcaagtgc attgcctgca tcttctacgg cgatatgctg
     3181 tgtgcgctgc gcaatcaggt ggccccctac gagaacgaaa agggcgctgc tgaccgcatg
     3241 gtggatcgct ggatcgcccg tcttggccgt gccttgctgg ccggaaaagg ctttacttcc
     3301 cgggaaatga agcacacctt cccgctcatt gccaaggact ttgccgccat cccggtcacc
     3361 cgggtgccca aggtcaaggt gggcgttgtg ggcgagatct acgtcaagta cagcccgctg
     3421 ggcaacaacg acctgcaaaa gtttttggaa agtcaggact gcgaggtgaa cttccccggc
     3481 ctgatgggct ttgtgcagta ctgcgccttc aacatgggcg aggatcatgt gctgtacggc
     3541 ggcaagctgg ctgtaaaggt gggcacggat cagttcctta attggctgga cagcgtggag
     3601 cgcgtcatgc tcaaggccga gacggacgcc gggttctatg cgccgggccc cttcaaggag
     3661 ctggtggaaa agcccaaggg agtcatctcg ctgggcgcaa aaatgggtga gggctggctg
     3721 ctgaccgccg agatgatcga gctggtgcag ggcggctacg gcaacattgt gtgtgcgcag
     3781 ccctttggct gcctgcccaa ccatatcgtg ggcaagggca tggtgaacaa gatccgtgcg
     3841 ctgtacccca gcgccaacat cacccccatc gactacgacc ccagcgccac ccgggtcaat
     3901 caggaaaacc gcatcaagct gatgctggcg gtcgcaaagg agcggctgaa cgcccctgtg
     3961 gaaactcagc cgcttacggc agagcagctt gccggcggcg ctccgcaggt cggcgctacc
     4021 gtgtaacagc ggttgctgta tgcggtgagc gtcctcgccc tctccgtcac ctacggtgac
     4081 acctctccca aggggagagg ccttggcaaa aagatgaagt ttgcgtggac tgccaagggc
     4141 tcccactttg ggggagctgg cgaacgtatg tgagcctgag agggcgagcc cgttaagagc
     4201 aagagcatct gcaacaatac tcgctgattt tcgacgacca gaagtgagtt gtgcaggtgc
     4261 tttcttgttt tacgtacaat tttacaggaa aggaaccgcc atggaaaagc ccgcagctgc
     4321 ctgttatcat ctgcccggcc tgttcgagtt ttacgagttg taccgccgtt ttttgccgct
     4381 gtaccgggaa caccgggaat atttttacga ctggtgcgcc atcggctcta tctacggcgc
     4441 accggcgggc tgcatctggg gcgggggacg catctcctgc ggcggggcag ctgcgcgcga
     4501 ggtgctggcg ctgctgcggg aatacggcat ctccgggcgg ctgaccttca gcaactccct
     4561 gctgcgggct gagcaccttg ccgacccgca gtgcaacgcc ttgtgcgaga agtttgccaa
     4621 ggcgggcagt gtgccaaacg gcgtgatcgt ccattcggat ttgctggcgg actatctgca
     4681 acagcgctgg ccggagctgt atctggtttc ctctaccacc aaggtgctca ccgattttgc
     4741 gcagctgcgg caggaactgg aaaagccgca gttccggtat gtggtgccgg atttccggtt
     4801 aaacccggca ctggaacagc tgcgcaccct gccgtcggag caaaaagcca aggtagagtt
     4861 tttgtgcaac gagtgctgct ggttcggctg caccgagcgc aagcgctgct acgagacggt
     4921 cagccgtcag aatctgggcg aggactgccc ggaccaccgc tgcgccgccc cggatgctgc
     4981 cgggggctat cgcttttcca aggcgatgcg cagccccgga tttatcgggg tggaggatat
     5041 ccggcagcgg tatctgcccg caggtttttc ccactttaaa atagagggca ggggacttgg
     5101 cagcgcactg gtgctggaat ttctgctcta ctacatgaca aagccggaat accagctgca
     5161 ggtgcgggag acaatttatc tggacaatat gctggatctt ttttaagaaa atcgcaccgg
     5221 gcagaccgtt ttctgtccgg tgcggttttt tgcctgcggg atttgcgccc gaaaactttc
     5281 ttttccctcc aaagcgtgtt acaataaata agatattatt tttagaagct gcttacgaaa
     5341 gcagcttcct gtaggagcag tgcatggaaa caacgcaaaa acagatcgta ctgggcattc
     5401 tggcccatgt ggactccggc aagaccaccc tctccgaggc catgctctac cgcgccggtg
     5461 ccatccgcaa gctggggcgg gtggatcacg gagacgcctt tctggatacc gacagcttgg
     5521 aaaaagcacg cggcatcacc atcttttcca agcaggcgct gcttacggcg ggcaatactg
     5581 ccatcaccct gctggacacc cccggccatg tggatttttc caccgagact gagcgcacct
     5641 tgcaggtgct ggattacgcc gtgctggtgg tcagcggaac ggacggcgtg cagagccata
     5701 ccgaaacgct gtggcggctg ctgcggcgct accatgtgcc cacctttgta tttgtgaata
     5761 aaatggactt gcccggcatg acccgggaac agctgcttac ccagctgaat caccgccttg
     5821 gcgagggctt tgtggatttt ggcgcagaac ctgccgcccg caacgaagca ctggcgctgt
     5881 gcgatgagca gctgatggaa aaaatgctgg acgcgggaac cttgaccgat gcggacatca
     5941 tccccgcagt tgcccggcgg cacgtttttc cgtgctggtt cggggcggca ctgcgtctgg
     6001 acggagtgga tgcacttctg gatgggcttg accgctgcac ccgcgccgcc ccggcactgc
     6061 acgcctttgg cgcaagggta ttcaaggtat cgcaggacga gcagggcacc cgcctgacat
     6121 ggctgcgggt caccggcggg gaactgaagg taaaggctct gctttccggc gaagcggacg
     6181 gtgagtcgtg ggcagaaaag gcaaaccagc tgcggctgta ttccggcgca aagtataccc
     6241 tgactgaggt catcggcccg ggacaggtat gcgccgtgac cggcctgacc catgcaaagc
     6301 ccggcaccgg gcttggggca gagcgggaca gcgatgtgcc ggtgctggaa ccggtgctca
     6361 gctatcaggt gctgctgccg gagggcgcgg atgtgcacgc cgcactgggc aagctgcacc
     6421 ggctggagga ggaagagccc cagctccatg tggtgtggaa cgaaagcttg ggcgagatcc
     6481 atgtgcagct gatgggcgag gtgcagctgg aggtgctgcg cagcctgctg gcagagcggt
     6541 tcgggctgga agtatccttt ggcccgggtg gcattttgta taaggagacc atcaccgagc
     6601 ccatggaggg cgtaggccac tacgagccgc tgcgccacta tgccgaggtg catctgctgc
     6661 tggaaccgct gccccggggc agcgggatgc agtttgccgc cgactgccgg gaagaggttc
     6721 tggacaaaaa ctggcagcgg ctggtgctga cccatctgga agaaaagcag caccttggcg
     6781 ttttgatcgg tgcaccgctg accgatataa aaatcaccct gctcaccggc aaagcgcacc
     6841 ttaagcacac cgagggcggc gatttccggc aggctaccta ccgtgccgtg cggcaggggc
     6901 tgatgctggc aaaaagccag ctgttagagc cgtggtatgc ctttcggctg gaagtgccgg
     6961 tggagaacat tggccgcgcc atgagtgata tccagcgcat ggagggcagc tttgacccgc
     7021 cggaaagcgg cgcggagacc gccaccctga ccggctttgc gccggtatcc accatgcgta
     7081 gctaccccat ggaggtggtc agctacaccc ggggcagggg acgtctgagc ctgacgatgg
     7141 acggctaccg cccctgtcac aatgcacagg aggtcattgc agagatcggc taccagccgg
     7201 agcatgatct ggaaaacccc gcagattccg tgttctgcgc ccatggtgcc ggttttgtgg
     7261 tgccgtggag cgaggtgcgc agccacatgc acgtggaaag cggctggggc aaggcaaagc
     7321 ccgcccgccc ggagacgcag gctgtgcccc agcgccgcgc catggcctac cgcgccacgc
     7381 tggaggagga tgccgagccg ctcaagattt ttgaacgcac ctacggcccc atcaagcggg
     7441 acccgctggc ggctttccgt ccggtgcaaa agaccgaacg cccggatttt gccgccgaac
     7501 agtgggaaat tgccccggag tatctgctgg tggacggcta caacatcatc tttgcgtggg
     7561 acgagctgaa tgcgctggca aaggaaagct tagacactgc ccgccatcgg ctgatggaca
     7621 ttctgtgcaa ctatcagggc taccagaagt gcgtgctcat tctggtgttc gatgcctacc
     7681 gcgtgcccgg cagcccgggt gccattgagc agtaccacaa catccatgtg gtctatacca
     7741 aggaggccga gaccgccgat atgttcatcg agcgggtcac ccacgagatc ggcaaaagcc
     7801 gccgcgtccg ggtggcgacc tcggacggta tggagcaggt catcatcctt ggtcacggcg
     7861 cactgcgcgt gtccgcccgg atgtttcacg aggaagtgca gaacgtggaa aagcagatcc
     7921 gcgcccttgt gcagggacag gcgtaaaggc tgacccctgt gaaaatggga tatcggaatg
     7981 cctgcgggcg ttccgatatc ccgagtacaa ataaaatttt ctttcttgtg aaaaagtcga
     8041 tttggaaaat cgttctctgg aggtgcaccc atggctgtgg aaattaccga agaatttgtc
     8101 tggcagagca tcccgccccg tgcccgagac agccataagg gtacctttgg cagcgtgctg
     8161 gcggtggcgg gcagtgcctt ttaccggggc gctgcgctgc tggcagccga gggtgcactg
     8221 cgcaccgggg cgggtatcgt tacccttgcc agtgtggaac cggtggtcag cgccgccgtc
     8281 acccgtctgc cggagtgctg cctgtgcccc tgtaaggagg gcgcacaggg cggcattgcg
     8341 ccggaaaatg tgccgctgct ccggcggcag aaggctaccg tactgctgct gggccccggc
     8401 cttggcggca cagcgcaaag cgccgcccgg gccgccgaga cccgcacgct ggtgcagcag
     8461 cttctgcccg gctttgccgg ggctgcggtg ctggacgcag acggcctgaa cgccgccgcc
     8521 cagctgctgg ccgagggcaa acccttcccg cacccggcgg gggagttggt agtcaccccg
     8581 caccccggcg agatggcgcg gctgaccggg ttttcggcgg cagaacttgc cgccgaccgg
     8641 gagggcatcg ccctgcacta tgccaaggcg tggaacgccg tggtggtgct caaaggggca
     8701 cacaccgtgg tggcaagccc ggacgggcgg gtgtgcgtga accccaccgg caacccgggg
     8761 cttgcccggg gcggcagcgg ggatgtgctg gctgggatgc ttgcggcgct gctggcctgc
     8821 ggtctgcccg cttacgaagc cgctgcctgt gcggtatacc tgcacggtgc cgccgccgac
     8881 cgcgccgccg caaagcgcgg cgagtacggg atgctgccgc acgatatcct gccggagctg
     8941 ggcgaactgt ttgcgtaaaa ccagagataa ccgagaaacg cggcagtttc acaaaacacc
     9001 gtgcagctgc cgctttttgg ggtgaaacga tttggaatgc cctccgcgtt gctctgggca
     9061 tattcagcgg aatgattatt ataatttgtg gttcagaaac gtctgcggac gtttctgaac
     9121 cactttttca cgctaggggg cgtgatggga aacggcagtt acagcgctcg tttcctgcgg
     9181 aaacggttgc gctgtaatag aaccatgcag attcaacccg gtgaaaatgg aatgcagaat
     9241 gtccgccgga tttagcggaa ctggctgagg tattcctcca ccgagcgggt catctccttg
     9301 gaaaaatcgg agttatactt gcggttgcag aaggcggtgc accactggtc aaagggggcg
     9361 tttccggctt tatagccgaa ggtgtcccgc agctctgcgc cgtccatggt gcggtagccg
     9421 ttttcgtgca cgatatgctc catggcgcag cgctggggtt ttacgcggtc cttctgttgc
     9481 tgggtgggcc agccgaacac cagcatcacc gccgggaaca catagtccgg cagatgcagc
     9541 agactgcgct gggtgtcgca gttttccatg atgtccccga tgtagcacga gccgatgcca
     9601 aagctttcgg cggcgaccac ggcgttctgg gcggcaatgg cagcatcggt gactgccagc
     9661 atcaaatcgc ccacacccgg agtgcggggc gtgcagccgg cctctaagta agcgtcgtac
     9721 cactttttgc agtcggcgca gaacaccagc accagcggtg ctttggcaat aaagggctgg
     9781 tggtcacagc tttcggccag cgcttccttc agtgccgggt cggtgatgtc taaaatggta
     9841 tacagctgct gacagcccgc agagggcgcc tgtgcggcag cttccaaaat ggcctgcttc
     9901 atctcagcag gaatgggctt ttcttcatac acccgcaccg acttgcggtc gaacaggctt
     9961 tgcaggatag ggttgcgctc agtcatggga acacctccgg tgttgtgttt attcgtagtc
    10021 gatgggtagg gtgggcaggc cgttcagttc cagcccggcg gtatgcccgg caatgtactg
    10081 gtagtagccc tgcgcggcga tcatcgcgcc gttgtcgccg cagaacttca gttccggcag
    10141 gtaaaccttg gcacccagct tctgggcacc gtcgttcacc agctggcgca gacggccgtt
    10201 ggcggctacg ccgccggcaa ggcacacctg ctttgccccg gtatcggcag cagccagcag
    10261 cagcttttcg gccagaatgc ccgcaatgcg ctcctgaaag ctggcagcaa ggtcgggcac
    10321 attcacttcc tcgcccttca tctgcgcctt gttcacctcg ttgagcacgg cggtctttaa
    10381 gccggaaaag ctcacgttgt acttgccctc cacatggggc accggcaggc ggtaggcctt
    10441 ggggtcgccg gtctt
//
