## Wed Jul 10 19:09:57 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_934860535.1/GCA_934860535.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934860535.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934860535.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NMLHFLOH_00001	1121115.AXVN01000010_gene2773	5.6e-81	239.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3Y05X@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
NMLHFLOH_00002	1121115.AXVN01000010_gene2774	4.03e-216	598.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00003	1121115.AXVN01000010_gene2775	1.61e-88	259.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3Y06A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NMLHFLOH_00004	1121115.AXVN01000010_gene2776	1.86e-187	523.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NMLHFLOH_00005	457412.RSAG_01431	2.03e-190	530.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3WGFX@541000|Ruminococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NMLHFLOH_00006	1121115.AXVN01000010_gene2778	1.26e-192	537.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3XYWM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NMLHFLOH_00007	1121115.AXVN01000010_gene2779	8.69e-180	500.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NMLHFLOH_00008	457412.RSAG_01428	1.05e-153	432.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3WIXN@541000|Ruminococcaceae	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NMLHFLOH_00009	1121115.AXVN01000010_gene2781	0.0	1041.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
NMLHFLOH_00010	457412.RSAG_01426	0.0	1035.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3WPDP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NMLHFLOH_00011	457412.RSAG_01425	0.0	1104.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,24CTB@186801|Clostridia,3WJZ8@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NMLHFLOH_00012	1121115.AXVN01000010_gene2784	0.0	968.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
NMLHFLOH_00013	457412.RSAG_01423	4.95e-215	593.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,3WGA3@541000|Ruminococcaceae	186801|Clostridia	U	ABC-type polysaccharide transport system permease component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NMLHFLOH_00014	1121115.AXVN01000010_gene2786	2.5e-201	558.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,3Y1FV@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_00015	457412.RSAG_01421	0.0	1835.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_00016	457412.RSAG_01420	3.13e-133	377.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,3WJEZ@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_00017	1121115.AXVN01000010_gene2789	1.64e-123	353.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NMLHFLOH_00018	457412.RSAG_01418	0.0	938.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	atsB	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NMLHFLOH_00019	1121115.AXVN01000010_gene2791	0.0	1061.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3Y1DA@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_00020	1121115.AXVN01000010_gene2792	0.0	913.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3Y10H@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
NMLHFLOH_00021	1121115.AXVN01000010_gene2793	4.22e-244	671.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
NMLHFLOH_00022	457412.RSAG_01414	0.0	980.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	araG_1	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NMLHFLOH_00023	1121115.AXVN01000010_gene2795	7.39e-233	643.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia,3Y10U@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NMLHFLOH_00024	1121115.AXVN01000010_gene2796	1.6e-226	626.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia,3Y1F9@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NMLHFLOH_00025	457412.RSAG_01411	4.8e-223	612.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NMLHFLOH_00026	457412.RSAG_01410	5.51e-205	567.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,3WGRW@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NMLHFLOH_00027	457412.RSAG_04514	1.43e-39	130.0	2CA4K@1|root,347XV@2|Bacteria,1VZ7Z@1239|Firmicutes,253MY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00028	1121115.AXVN01000010_gene2800	2.83e-210	582.0	2DS3C@1|root,33EBY@2|Bacteria,1U8VV@1239|Firmicutes,24EGD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
NMLHFLOH_00029	457412.RSAG_01408	9.37e-295	807.0	COG4632@1|root,COG5263@1|root,COG4632@2|Bacteria,COG5263@2|Bacteria,1TR6Z@1239|Firmicutes,25B3H@186801|Clostridia,3WJIW@541000|Ruminococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
NMLHFLOH_00030	1121115.AXVN01000010_gene2802	7.51e-23	87.8	2CA4N@1|root,2ZQ5H@2|Bacteria,1W5T5@1239|Firmicutes,256DT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00031	1121115.AXVN01000010_gene2804	9.69e-317	861.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3XZB7@572511|Blautia	186801|Clostridia	EK	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NMLHFLOH_00032	457412.RSAG_01405	0.0	912.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WIPN@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NMLHFLOH_00033	457412.RSAG_01404	2.87e-251	689.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NMLHFLOH_00034	457412.RSAG_01403	0.0	907.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NMLHFLOH_00035	457412.RSAG_01402	1.85e-136	386.0	2BCDS@1|root,325Z7@2|Bacteria,1URYW@1239|Firmicutes,259WP@186801|Clostridia,3WQU2@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00036	457412.RSAG_01401	2.09e-63	193.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3WKW0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00037	457412.RSAG_01400	0.0	1500.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae	186801|Clostridia	C	aconitate hydratase	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NMLHFLOH_00038	457412.RSAG_01390	5.46e-169	471.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NMLHFLOH_00039	1121115.AXVN01000037_gene3264	1.06e-257	707.0	COG1879@1|root,COG1879@2|Bacteria,1UZFA@1239|Firmicutes,249QV@186801|Clostridia,3XYTX@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	rbsB_4	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NMLHFLOH_00040	1121115.AXVN01000037_gene3263	2.9e-56	175.0	2EC1A@1|root,3360H@2|Bacteria,1VHMT@1239|Firmicutes,24S6Y@186801|Clostridia,3Y1SK@572511|Blautia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
NMLHFLOH_00041	1121115.AXVN01000037_gene3262	7.79e-93	271.0	2BAXA@1|root,324CZ@2|Bacteria,1UQP9@1239|Firmicutes,258FM@186801|Clostridia,3Y1K7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00042	457412.RSAG_04512	1.27e-172	482.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NMLHFLOH_00043	1121115.AXVN01000037_gene3260	1.25e-56	176.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y1RW@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NMLHFLOH_00044	1121115.AXVN01000037_gene3259	1.94e-91	270.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
NMLHFLOH_00045	457412.RSAG_01381	1.82e-120	344.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NMLHFLOH_00046	1121115.AXVN01000037_gene3257	0.0	978.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3Y1A3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NMLHFLOH_00047	1121115.AXVN01000037_gene3256	2.69e-195	542.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3Y0ZD@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NMLHFLOH_00048	1121115.AXVN01000037_gene3255	0.0	909.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3Y1D7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NMLHFLOH_00049	1121115.AXVN01000037_gene3254	1.73e-89	262.0	COG0355@1|root,COG0355@2|Bacteria,1TTR7@1239|Firmicutes,25MVC@186801|Clostridia,3Y1KM@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_DE,ATP-synt_DE_N
NMLHFLOH_00050	457412.RSAG_02207	8.83e-286	780.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3WH96@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NMLHFLOH_00051	1121115.AXVN01000037_gene3252	0.0	879.0	COG1070@1|root,COG1070@2|Bacteria,1TSEJ@1239|Firmicutes,24AT3@186801|Clostridia,3Y1CK@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NMLHFLOH_00053	1121115.AXVN01000037_gene3251	0.0	1132.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3Y19R@572511|Blautia	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NMLHFLOH_00054	1121115.AXVN01000037_gene3250	2.28e-53	167.0	2DWC0@1|root,33ZIT@2|Bacteria,1VY40@1239|Firmicutes,252ED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00055	457412.RSAG_02211	3.32e-239	657.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
NMLHFLOH_00056	457412.RSAG_02212	3.95e-273	747.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WICI@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NMLHFLOH_00057	1121115.AXVN01000037_gene3247	0.0	1065.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NMLHFLOH_00058	1121115.AXVN01000037_gene3246	2.88e-17	75.9	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NMLHFLOH_00059	1121115.AXVN01000037_gene3245	3.23e-80	239.0	2CFUE@1|root,33V7A@2|Bacteria,1VUR9@1239|Firmicutes,250BS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00060	1121115.AXVN01000037_gene3244	7.82e-118	337.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3Y2CS@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NMLHFLOH_00061	457412.RSAG_02216	1.08e-247	681.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3WHMJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NMLHFLOH_00062	1121115.AXVN01000037_gene3242	0.0	1057.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3Y0X8@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NMLHFLOH_00063	457412.RSAG_02218	4.83e-255	700.0	COG3347@1|root,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,25BHR@186801|Clostridia	186801|Clostridia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NMLHFLOH_00064	1121115.AXVN01000037_gene3240	0.0	1731.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
NMLHFLOH_00065	1121115.AXVN01000037_gene3239	0.0	1178.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3XYY0@572511|Blautia	186801|Clostridia	T	GTP-binding protein TypA BipA homolog	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
NMLHFLOH_00066	1121115.AXVN01000037_gene3238	1.25e-148	418.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
NMLHFLOH_00067	457412.RSAG_02222	4.24e-109	314.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NMLHFLOH_00068	1121115.AXVN01000125_gene3805	1.52e-207	574.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NMLHFLOH_00069	457412.RSAG_02224	1.49e-176	492.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3WH3Y@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NMLHFLOH_00070	457412.RSAG_02225	5.62e-292	798.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00071	1121115.AXVN01000125_gene3808	2.93e-26	105.0	2EYMV@1|root,33RVF@2|Bacteria,1VSPB@1239|Firmicutes,24XPM@186801|Clostridia,3Y0UE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00072	1121115.AXVN01000125_gene3809	2.81e-182	507.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,3XYK1@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisA	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
NMLHFLOH_00073	1121115.AXVN01000125_gene3810	6.26e-118	338.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NMLHFLOH_00074	1121115.AXVN01000125_gene3811	0.0	1018.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NMLHFLOH_00075	457412.RSAG_02231	0.0	1656.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WGPN@541000|Ruminococcaceae	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NMLHFLOH_00076	457412.RSAG_02232	0.0	961.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NMLHFLOH_00077	457412.RSAG_02233	1.46e-204	566.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3WJQB@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_00078	1121115.AXVN01000028_gene195	7.79e-203	561.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia,3XZ57@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NMLHFLOH_00079	1121115.AXVN01000028_gene197	3.29e-234	644.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NMLHFLOH_00080	1121115.AXVN01000028_gene198	3.59e-102	296.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NMLHFLOH_00081	1121115.AXVN01000028_gene199	2.27e-288	788.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XYWS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NMLHFLOH_00082	1121115.AXVN01000028_gene200	1.63e-280	768.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NMLHFLOH_00083	457412.RSAG_02239	4.17e-206	574.0	COG5523@1|root,COG5523@2|Bacteria,1TTE0@1239|Firmicutes,25M7C@186801|Clostridia,3WMQF@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NMLHFLOH_00084	457412.RSAG_02240	1.01e-309	843.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NMLHFLOH_00085	457412.RSAG_02241	0.0	1370.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
NMLHFLOH_00086	1121115.AXVN01000028_gene204	2.01e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_00087	457412.RSAG_02243	3.56e-47	151.0	COG1925@1|root,COG1925@2|Bacteria,1VWWX@1239|Firmicutes,252H5@186801|Clostridia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00088	457412.RSAG_02244	2.02e-62	191.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3WKTD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
NMLHFLOH_00089	457412.RSAG_02245	1.76e-196	545.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WHGA@541000|Ruminococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
NMLHFLOH_00090	457412.RSAG_02246	0.0	1068.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
NMLHFLOH_00091	1121115.AXVN01000028_gene209	2.15e-207	575.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1
NMLHFLOH_00092	457412.RSAG_02248	5.22e-184	515.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WJDM@541000|Ruminococcaceae	186801|Clostridia	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1,OppC_N
NMLHFLOH_00093	457412.RSAG_02249	2.42e-236	650.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NMLHFLOH_00094	457412.RSAG_04635	1.99e-237	652.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NMLHFLOH_00095	457412.RSAG_02250	5.09e-172	481.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NMLHFLOH_00096	457412.RSAG_02251	2.91e-176	491.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
NMLHFLOH_00097	1121115.AXVN01000028_gene215	0.0	1649.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3Y18M@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_00098	1121115.AXVN01000028_gene216	0.0	942.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,3XYWJ@572511|Blautia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
NMLHFLOH_00099	1121115.AXVN01000028_gene217	1.46e-118	339.0	COG0614@1|root,COG0614@2|Bacteria,1V6JK@1239|Firmicutes,24KN9@186801|Clostridia,3Y12K@572511|Blautia	186801|Clostridia	P	abc-type fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00100	457412.RSAG_02255	1.49e-156	440.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3WIU3@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-2 C20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NMLHFLOH_00101	457412.RSAG_02256	4.31e-194	539.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WJGT@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NMLHFLOH_00102	457412.RSAG_02257	4.48e-173	483.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WMU4@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
NMLHFLOH_00104	126957.SMAR004755-PA	2.03e-08	65.5	KOG0032@1|root,KOG0032@2759|Eukaryota,38GFU@33154|Opisthokonta,3BAQ1@33208|Metazoa,3CY7G@33213|Bilateria,41VIP@6656|Arthropoda	33208|Metazoa	T	Death domain	DAPK1	GO:0000149,GO:0000166,GO:0001952,GO:0002376,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004683,GO:0005488,GO:0005515,GO:0005516,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005856,GO:0005884,GO:0005886,GO:0006355,GO:0006417,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006937,GO:0006940,GO:0006950,GO:0006952,GO:0006955,GO:0006979,GO:0007088,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007346,GO:0007399,GO:0008022,GO:0008134,GO:0008140,GO:0008144,GO:0008150,GO:0008152,GO:0008219,GO:0008360,GO:0008625,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010469,GO:0010506,GO:0010508,GO:0010556,GO:0010558,GO:0010564,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010810,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0015629,GO:0016020,GO:0016301,GO:0016310,GO:0016604,GO:0016605,GO:0016740,GO:0016772,GO:0016773,GO:0017016,GO:0017048,GO:0017075,GO:0017076,GO:0017148,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0019904,GO:0019905,GO:0022008,GO:0022603,GO:0022604,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030111,GO:0030154,GO:0030155,GO:0030162,GO:0030177,GO:0030182,GO:0030275,GO:0030334,GO:0030335,GO:0030554,GO:0031267,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031329,GO:0031331,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032270,GO:0032409,GO:0032412,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032956,GO:0032970,GO:0033043,GO:0033194,GO:0033554,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034599,GO:0034762,GO:0034765,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0040012,GO:0040017,GO:0042221,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043269,GO:0043280,GO:0043281,GO:0043412,GO:0043519,GO:0043522,GO:0044057,GO:0044087,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0045087,GO:0045121,GO:0045862,GO:0046777,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051020,GO:0051049,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051239,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051270,GO:0051272,GO:0051336,GO:0051345,GO:0051493,GO:0051716,GO:0051726,GO:0051783,GO:0051893,GO:0052547,GO:0052548,GO:0060255,GO:0060548,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070887,GO:0071310,GO:0071345,GO:0071346,GO:0071447,GO:0071704,GO:0071944,GO:0080090,GO:0090109,GO:0090257,GO:0090263,GO:0097159,GO:0097190,GO:0097191,GO:0097367,GO:0098589,GO:0098805,GO:0098857,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0099601,GO:0140096,GO:1900449,GO:1901265,GO:1901363,GO:1901564,GO:1901700,GO:1901701,GO:1901888,GO:1902041,GO:1902042,GO:1903391,GO:1903506,GO:1904062,GO:2000112,GO:2000113,GO:2000116,GO:2000145,GO:2000147,GO:2000249,GO:2000310,GO:2001056,GO:2001141,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238,GO:2001239,GO:2001241,GO:2001257	2.7.11.1	ko:K08803	ko04140,ko05200,ko05219,map04140,map05200,map05219	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Ank_2,Ank_4,Ank_5,Death,Pkinase
NMLHFLOH_00106	1121115.AXVN01000028_gene221	0.0	1801.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg
NMLHFLOH_00107	457412.RSAG_02260	1.71e-209	579.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,3WRR9@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_00108	457412.RSAG_02261	1.11e-284	777.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NMLHFLOH_00109	457412.RSAG_02262	1.94e-91	267.0	COG1943@1|root,COG1943@2|Bacteria,1V5MU@1239|Firmicutes,24HFH@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NMLHFLOH_00110	457412.RSAG_02263	8.68e-278	759.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,24CV7@186801|Clostridia,3WR4V@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_00111	1121115.AXVN01000028_gene224	4.62e-252	692.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3Y10Q@572511|Blautia	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
NMLHFLOH_00112	457412.RSAG_02265	3.42e-41	135.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NMLHFLOH_00113	1121115.AXVN01000028_gene226	3.46e-53	166.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NMLHFLOH_00114	1232452.BAIB02000020_gene2685	2.32e-25	103.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24ET5@186801|Clostridia	186801|Clostridia	K	cog cog2390	-	-	-	-	-	-	-	-	-	-	-	-	Sugar-bind
NMLHFLOH_00115	742733.HMPREF9469_02841	9.93e-121	355.0	COG0679@1|root,COG0679@2|Bacteria,1V0ZS@1239|Firmicutes,24CQ0@186801|Clostridia,21ZFT@1506553|Lachnoclostridium	186801|Clostridia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NMLHFLOH_00117	1437608.BBIA_1899	5.91e-96	293.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4D06I@85004|Bifidobacteriales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NMLHFLOH_00118	457421.CBFG_02152	5.34e-172	497.0	COG0531@1|root,COG0531@2|Bacteria,1V0MG@1239|Firmicutes,25P28@186801|Clostridia,26ABY@186813|unclassified Clostridiales	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NMLHFLOH_00119	457412.RSAG_02267	1.25e-91	279.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3WGRZ@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NMLHFLOH_00120	1437608.BBIA_1899	6.75e-86	267.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4D06I@85004|Bifidobacteriales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NMLHFLOH_00121	411459.RUMOBE_04079	1.92e-201	563.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3Y1DP@572511|Blautia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
NMLHFLOH_00122	608534.GCWU000341_02211	1.37e-22	91.3	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NMLHFLOH_00123	411467.BACCAP_03149	4.69e-15	72.8	2FKMI@1|root,34C8H@2|Bacteria,1W1PW@1239|Firmicutes,24PI6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3232
NMLHFLOH_00124	457412.RSAG_02272	1.07e-93	274.0	2DNMV@1|root,32Y6A@2|Bacteria,1VFC4@1239|Firmicutes,24QMI@186801|Clostridia,3WMGA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00127	457412.RSAG_02275	4.39e-133	377.0	2EJGK@1|root,33D7H@2|Bacteria,1VMPJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00128	457412.RSAG_02276	1.1e-139	395.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NMLHFLOH_00129	1121115.AXVN01000038_gene3315	1.94e-60	186.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,3Y1WZ@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NMLHFLOH_00130	1121115.AXVN01000038_gene3316	1.33e-91	267.0	COG1669@1|root,COG1669@2|Bacteria,1U3WZ@1239|Firmicutes,25933@186801|Clostridia,3Y22N@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
NMLHFLOH_00131	457412.RSAG_02279	3.31e-142	401.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3WRQY@541000|Ruminococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NMLHFLOH_00132	457412.RSAG_02280	0.0	1609.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_00133	1121115.AXVN01000038_gene3319	1.01e-32	113.0	2FJZK@1|root,34BMY@2|Bacteria,1VZAP@1239|Firmicutes,2533H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00134	1121115.AXVN01000038_gene3321	1.47e-303	830.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00135	457412.RSAG_02284	3.89e-265	726.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WH5F@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NMLHFLOH_00136	457412.RSAG_02285	2.29e-252	691.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3WI2M@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NMLHFLOH_00137	457412.RSAG_02286	0.0	904.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WHVA@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	gph	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
NMLHFLOH_00138	457412.RSAG_02287	6.66e-298	814.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00139	457412.RSAG_02288	1.78e-123	351.0	COG0350@1|root,COG0350@2|Bacteria,1VA03@1239|Firmicutes,24JAA@186801|Clostridia,3WS5T@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567,ko:K13531	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
NMLHFLOH_00140	457412.RSAG_02289	2.22e-192	534.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3WGSS@541000|Ruminococcaceae	186801|Clostridia	J	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
NMLHFLOH_00141	457412.RSAG_02290	6.21e-68	206.0	COG0784@1|root,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
NMLHFLOH_00142	457412.RSAG_02291	4.92e-91	265.0	2E2GC@1|root,32XKF@2|Bacteria,1VCKF@1239|Firmicutes,24QFN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00143	1121115.AXVN01000038_gene3346	4.79e-104	300.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3Y0WP@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NMLHFLOH_00144	457412.RSAG_02293	4.26e-118	337.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,3WJJI@541000|Ruminococcaceae	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_00146	457412.RSAG_02294	2.57e-124	356.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00147	457412.RSAG_02295	3.78e-293	798.0	COG0673@1|root,COG0673@2|Bacteria,1V0MQ@1239|Firmicutes,24CZ7@186801|Clostridia,3WMEG@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NMLHFLOH_00148	1121115.AXVN01000038_gene3330	7.88e-305	831.0	COG2182@1|root,COG2182@2|Bacteria,1V961@1239|Firmicutes,24MCD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00149	1121115.AXVN01000038_gene3331	5.64e-201	558.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_00150	1121115.AXVN01000038_gene3332	1.1e-191	533.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3XZGR@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_00151	1121115.AXVN01000038_gene3333	0.0	1091.0	COG2972@1|root,COG2972@2|Bacteria,1UZWA@1239|Firmicutes,24EGG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NMLHFLOH_00152	1121115.AXVN01000038_gene3334	0.0	963.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V2J2@1239|Firmicutes,24CQK@186801|Clostridia,3Y1VC@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NMLHFLOH_00153	1121115.AXVN01000038_gene3335	1.35e-127	363.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3Y025@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
NMLHFLOH_00154	1121115.AXVN01000038_gene3336	4.15e-94	273.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,24ZZZ@186801|Clostridia	186801|Clostridia	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
NMLHFLOH_00155	457412.RSAG_02303	5.17e-176	491.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3WG7F@541000|Ruminococcaceae	186801|Clostridia	P	Metal cation transporter, ZIP family	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NMLHFLOH_00156	457412.RSAG_02304	1.17e-104	301.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3WMN1@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NMLHFLOH_00157	457412.RSAG_02305	4.29e-119	341.0	COG1595@1|root,COG1595@2|Bacteria,1VGKP@1239|Firmicutes,24RUX@186801|Clostridia,3WKQD@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_00158	1121115.AXVN01000131_gene738	1.09e-179	501.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00159	457412.RSAG_02307	3.38e-56	176.0	2BQ4H@1|root,32IYV@2|Bacteria,1US27@1239|Firmicutes,25A0K@186801|Clostridia,3WQZK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00161	1121115.AXVN01000006_gene2181	0.0	868.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3XZ02@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NMLHFLOH_00162	411459.RUMOBE_02489	0.0	1944.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,3Y1AM@572511|Blautia	186801|Clostridia	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00163	411459.RUMOBE_02490	2.94e-71	214.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3Y1M3@572511|Blautia	186801|Clostridia	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NMLHFLOH_00164	411459.RUMOBE_02491	3.42e-84	248.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,3Y1IN@572511|Blautia	186801|Clostridia	S	COG NOG13239 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NMLHFLOH_00165	931276.Cspa_c21230	9.91e-56	186.0	COG0716@1|root,COG1149@1|root,COG0716@2|Bacteria,COG1149@2|Bacteria,1V767@1239|Firmicutes,24C3D@186801|Clostridia,36EWY@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Flavodoxin_5
NMLHFLOH_00166	411459.RUMOBE_02492	0.0	916.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3Y1AZ@572511|Blautia	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
NMLHFLOH_00167	411459.RUMOBE_02493	1.34e-299	816.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3Y18K@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Rep_trans
NMLHFLOH_00168	471875.RUMLAC_01426	1.66e-22	86.7	2DZ2V@1|root,34C88@2|Bacteria,1W361@1239|Firmicutes,254XY@186801|Clostridia,3WQT4@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
NMLHFLOH_00169	411459.RUMOBE_02495	1.69e-41	136.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y0EY@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00170	411461.DORFOR_02736	5.59e-114	327.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NMLHFLOH_00171	411459.RUMOBE_02497	2.03e-96	280.0	COG4734@1|root,COG4734@2|Bacteria,1V1UX@1239|Firmicutes,24GIR@186801|Clostridia	186801|Clostridia	S	COG NOG09588 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00172	457412.RSAG_00818	2.75e-116	333.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,3WRS5@541000|Ruminococcaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NMLHFLOH_00173	457412.RSAG_00816	7.42e-89	260.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,3WIZ3@541000|Ruminococcaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
NMLHFLOH_00174	457412.RSAG_00815	0.0	1560.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,3WHEW@541000|Ruminococcaceae	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NMLHFLOH_00175	411459.RUMOBE_02502	0.0	1229.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,3XYX2@572511|Blautia	186801|Clostridia	M	COG NOG05967 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00176	457412.RSAG_00813	4.38e-242	665.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3WHJ0@541000|Ruminococcaceae	186801|Clostridia	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
NMLHFLOH_00177	471875.RUMLAC_01436	8.72e-204	565.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3WI6V@541000|Ruminococcaceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NMLHFLOH_00178	457412.RSAG_00811	1.45e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WIJ0@541000|Ruminococcaceae	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_00179	457412.RSAG_00810	0.0	866.0	COG0642@1|root,COG2205@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3WIVN@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_00180	457412.RSAG_00809	2.84e-115	330.0	29UU9@1|root,30G6R@2|Bacteria,1UFAI@1239|Firmicutes,24D25@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00181	457412.RSAG_00808	4.27e-37	124.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,3WKJD@541000|Ruminococcaceae	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
NMLHFLOH_00182	457412.RSAG_00807	1.23e-75	226.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,24HFJ@186801|Clostridia,3WJZF@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_00183	457412.RSAG_00806	2.06e-93	273.0	COG1191@1|root,COG1191@2|Bacteria,1UJ7B@1239|Firmicutes,24KND@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
NMLHFLOH_00184	457412.RSAG_00805	1.48e-49	157.0	2AJW5@1|root,32RUV@2|Bacteria,1UHK2@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NMLHFLOH_00185	457412.RSAG_00804	9.12e-28	100.0	2EJDE@1|root,33D4F@2|Bacteria,1VMA3@1239|Firmicutes,24X75@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00186	457412.RSAG_00803	0.0	1035.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WGP9@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_00187	457412.RSAG_00802	3.11e-84	248.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3WHS3@541000|Ruminococcaceae	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NMLHFLOH_00188	457412.RSAG_00801	0.0	908.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WIPD@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_00189	1121115.AXVN01000006_gene2178	1.45e-131	372.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24G9A@186801|Clostridia,3Y058@572511|Blautia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_00191	457412.RSAG_00798	4.85e-102	296.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,3WQH6@541000|Ruminococcaceae	186801|Clostridia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
NMLHFLOH_00192	1121115.AXVN01000006_gene2175	2.73e-50	159.0	arCOG06833@1|root,32SGF@2|Bacteria,1U5WJ@1239|Firmicutes,25K3K@186801|Clostridia,3Y0UZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00193	457412.RSAG_00796	1.16e-72	218.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24T0M@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
NMLHFLOH_00194	1121115.AXVN01000006_gene2173	1.13e-56	181.0	COG1396@1|root,COG1396@2|Bacteria,1UVI3@1239|Firmicutes,24SEF@186801|Clostridia,3Y1RY@572511|Blautia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00195	1229751.R9QLK3_9CAUD	1.2e-15	71.6	4QB0K@10239|Viruses,4QV7M@35237|dsDNA viruses  no RNA stage,4QREE@28883|Caudovirales,4QM85@10699|Siphoviridae	10699|Siphoviridae	S	Protein of unknown function (DUF739)	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00198	1121115.AXVN01000006_gene2172	9.81e-27	97.8	2FGK7@1|root,348FZ@2|Bacteria,1W09F@1239|Firmicutes,25375@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00202	1235792.C808_03084	3.13e-36	135.0	2APHD@1|root,31EKC@2|Bacteria,1V7GX@1239|Firmicutes,24GBC@186801|Clostridia,27PAK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00203	1385420.FRA_31c04710	1.56e-13	70.5	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,1S3YC@1236|Gammaproteobacteria,460RH@72273|Thiotrichales	72273|Thiotrichales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
NMLHFLOH_00204	411459.RUMOBE_00951	1.19e-79	240.0	2F1A0@1|root,33UB0@2|Bacteria,1VUUK@1239|Firmicutes,24Q4U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00205	999413.HMPREF1094_04705	1.7e-176	523.0	28KSN@1|root,2Z9PR@2|Bacteria,1TSZJ@1239|Firmicutes,3VS4J@526524|Erysipelotrichia	526524|Erysipelotrichia	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
NMLHFLOH_00206	411459.RUMOBE_00949	6.19e-92	292.0	COG1475@1|root,COG1475@2|Bacteria,1TPT0@1239|Firmicutes,259Z7@186801|Clostridia,3Y0Y1@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	DUF3850,ParBc
NMLHFLOH_00207	1235798.C817_05493	1.85e-21	87.0	2EJY1@1|root,33DNP@2|Bacteria,1VKTV@1239|Firmicutes,24VPW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00208	693746.OBV_24070	6.9e-15	72.4	2CEPU@1|root,30FWJ@2|Bacteria,1UESN@1239|Firmicutes,25PBZ@186801|Clostridia,2N8HU@216572|Oscillospiraceae	693746.OBV_24070|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00213	1235792.C808_05326	5.9e-57	181.0	2DS3B@1|root,33EBS@2|Bacteria,1VM4J@1239|Firmicutes,24N4N@186801|Clostridia,27QBE@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00217	1304866.K413DRAFT_1217	8.52e-41	139.0	29X9K@1|root,30IZ3@2|Bacteria,1UJW6@1239|Firmicutes,24PGD@186801|Clostridia,36SY0@31979|Clostridiaceae	186801|Clostridia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
NMLHFLOH_00218	397288.C806_00077	1.85e-51	171.0	29979@1|root,2ZWAK@2|Bacteria,1W5BZ@1239|Firmicutes,24X6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00219	1414720.CBYM010000002_gene575	4.23e-274	765.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,36E5Y@31979|Clostridiaceae	186801|Clostridia	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_1
NMLHFLOH_00220	1414720.CBYM010000001_gene697	1.28e-131	391.0	COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,36H1A@31979|Clostridiaceae	186801|Clostridia	S	Phage portal protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
NMLHFLOH_00221	397288.C806_00074	2.84e-27	105.0	COG3740@1|root,COG3740@2|Bacteria,1VUUG@1239|Firmicutes,24HV8@186801|Clostridia	186801|Clostridia	S	Phage prohead protease, HK97 family	-	-	-	ko:K06904	-	-	-	-	ko00000	-	-	-	Peptidase_S78
NMLHFLOH_00222	397288.C806_00073	2.32e-143	419.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia	186801|Clostridia	S	phage major capsid protein, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
NMLHFLOH_00223	1304866.K413DRAFT_1227	3.13e-24	95.1	2C51R@1|root,2ZHBZ@2|Bacteria,1W22Q@1239|Firmicutes,24UFX@186801|Clostridia,36N4W@31979|Clostridiaceae	186801|Clostridia	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
NMLHFLOH_00224	500633.CLOHIR_00369	1.72e-14	71.2	COG5614@1|root,COG5614@2|Bacteria	2|Bacteria	S	Phage head-tail joining protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
NMLHFLOH_00225	397288.C806_00070	0.000433	46.2	2BT3X@1|root,32N8G@2|Bacteria,1U4T0@1239|Firmicutes,25PZE@186801|Clostridia,27SKB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
NMLHFLOH_00227	1408324.JNJK01000006_gene1387	9.33e-104	316.0	28ISD@1|root,2Z8RJ@2|Bacteria,1TQJ7@1239|Firmicutes,2499A@186801|Clostridia,27MUV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage tail sheath C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C
NMLHFLOH_00228	1408324.JNJK01000006_gene1388	1.65e-45	151.0	2DKUN@1|root,30DF7@2|Bacteria,1VAF1@1239|Firmicutes,24GEC@186801|Clostridia	186801|Clostridia	S	Phage tail tube protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2001
NMLHFLOH_00229	665950.HMPREF1025_01345	2.58e-10	62.4	2ECG1@1|root,336EB@2|Bacteria,1VF5A@1239|Firmicutes,24G0K@186801|Clostridia	186801|Clostridia	S	PFAM Phage XkdN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
NMLHFLOH_00230	398512.JQKC01000009_gene461	2.69e-83	284.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes,25EEJ@186801|Clostridia,3WGX8@541000|Ruminococcaceae	186801|Clostridia	S	tail tape measure protein, TP901	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
NMLHFLOH_00231	290402.Cbei_3394	7.05e-19	86.7	COG1652@1|root,COG1652@2|Bacteria,1VE0Z@1239|Firmicutes,25DK5@186801|Clostridia,36UCJ@31979|Clostridiaceae	186801|Clostridia	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00232	1408324.JNJK01000006_gene1393	1.22e-73	246.0	COG0791@1|root,COG0791@2|Bacteria,1V42E@1239|Firmicutes,24FF0@186801|Clostridia,27NC7@186928|unclassified Lachnospiraceae	186801|Clostridia	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase,NLPC_P60
NMLHFLOH_00234	1095750.HMPREF9970_2281	8.73e-32	117.0	COG3628@1|root,COG3628@2|Bacteria,1UJW5@1239|Firmicutes,25FBV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
NMLHFLOH_00235	397288.C806_00059	1.84e-95	295.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,27K7C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
NMLHFLOH_00236	357809.Cphy_0794	2.01e-11	67.0	COG4385@1|root,COG4385@2|Bacteria,1V7MM@1239|Firmicutes,24IV9@186801|Clostridia,223HU@1506553|Lachnoclostridium	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
NMLHFLOH_00238	1499689.CCNN01000007_gene1877	2.57e-40	136.0	2DMQX@1|root,32T39@2|Bacteria,1VCAV@1239|Firmicutes,24NI5@186801|Clostridia	186801|Clostridia	S	PFAM S23 ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
NMLHFLOH_00239	1499689.CCNN01000007_gene1878	1.77e-140	410.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24BRP@186801|Clostridia,36FNF@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NMLHFLOH_00243	665950.HMPREF1025_02516	4.17e-13	63.2	2DR0T@1|root,339Q5@2|Bacteria,1VQ5C@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00244	397288.C806_00056	3.27e-50	161.0	2DMRF@1|root,32T6H@2|Bacteria,1VDD8@1239|Firmicutes,24P5Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00245	1121115.AXVN01000006_gene2171	1.4e-58	181.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,3Y0FM@572511|Blautia	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
NMLHFLOH_00246	411459.RUMOBE_01085	1.9e-84	275.0	2DN8Y@1|root,32W5U@2|Bacteria,1VBWS@1239|Firmicutes,24PRC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00247	411459.RUMOBE_00968	1.17e-17	73.9	COG3546@1|root,COG3546@2|Bacteria,1UF7I@1239|Firmicutes,25K8A@186801|Clostridia,3Y21Y@572511|Blautia	186801|Clostridia	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
NMLHFLOH_00248	1121115.AXVN01000006_gene2169	1.35e-64	196.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
NMLHFLOH_00249	1121115.AXVN01000006_gene2168	9.8e-52	165.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
NMLHFLOH_00250	457412.RSAG_00787	7.83e-199	550.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3WIQB@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NMLHFLOH_00251	1121115.AXVN01000006_gene2166	4.17e-157	440.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_00252	1121115.AXVN01000006_gene2165	0.0	1303.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NMLHFLOH_00253	1121115.AXVN01000006_gene2164	2.85e-275	802.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3XYKM@572511|Blautia	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NMLHFLOH_00254	457412.RSAG_00783	1.53e-267	734.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NMLHFLOH_00255	1121115.AXVN01000006_gene2162	1.02e-46	150.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3Y0HG@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NMLHFLOH_00256	457412.RSAG_00781	2.44e-213	590.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae	186801|Clostridia	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NMLHFLOH_00257	457412.RSAG_00780	4.09e-166	465.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NMLHFLOH_00258	457412.RSAG_00779	6.9e-298	812.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NMLHFLOH_00259	1121115.AXVN01000006_gene2158	3.29e-99	288.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
NMLHFLOH_00260	1121115.AXVN01000006_gene2157	1.23e-96	281.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NMLHFLOH_00261	1121115.AXVN01000006_gene2156	0.0	887.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NMLHFLOH_00262	457412.RSAG_00775	0.0	1117.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3WGZ8@541000|Ruminococcaceae	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
NMLHFLOH_00263	1121115.AXVN01000006_gene2154	0.0	976.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NMLHFLOH_00264	457412.RSAG_00773	0.0	1160.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3WGMT@541000|Ruminococcaceae	186801|Clostridia	L	helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NMLHFLOH_00265	1121115.AXVN01000006_gene2152	2.8e-135	382.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NMLHFLOH_00266	1121115.AXVN01000006_gene2151	1.28e-265	727.0	COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,24K83@186801|Clostridia,3Y0X1@572511|Blautia	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00267	457412.RSAG_00770	4.03e-240	659.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
NMLHFLOH_00268	1121115.AXVN01000006_gene2149	1.77e-119	341.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
NMLHFLOH_00269	457412.RSAG_00768	9.49e-35	119.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NMLHFLOH_00270	1121115.AXVN01000006_gene2147	1.25e-80	240.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NMLHFLOH_00271	457412.RSAG_00766	2.53e-267	735.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WITJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
NMLHFLOH_00272	457412.RSAG_00765	9.6e-125	356.0	29TPZ@1|root,30EY4@2|Bacteria,1UD4F@1239|Firmicutes,2591T@186801|Clostridia,3WMKP@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AF
NMLHFLOH_00273	1121115.AXVN01000006_gene2144	2.93e-64	197.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
NMLHFLOH_00274	457412.RSAG_00763	4.89e-160	450.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
NMLHFLOH_00275	457412.RSAG_00762	0.0	1055.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NMLHFLOH_00276	1121115.AXVN01000006_gene2141	8.03e-79	235.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
NMLHFLOH_00277	1121115.AXVN01000006_gene2140	5.6e-73	219.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NMLHFLOH_00278	1121115.AXVN01000006_gene2139	5.45e-278	762.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3XZS9@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NMLHFLOH_00279	457412.RSAG_00758	2.03e-47	152.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3WMSQ@541000|Ruminococcaceae	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NMLHFLOH_00280	457412.RSAG_00757	4.17e-204	565.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NMLHFLOH_00281	1121115.AXVN01000006_gene2136	0.0	1233.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NMLHFLOH_00282	457412.RSAG_00755	5.27e-194	538.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NMLHFLOH_00283	1121115.AXVN01000006_gene2134	2.08e-204	565.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NMLHFLOH_00284	457412.RSAG_00753	6.17e-99	288.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NMLHFLOH_00285	457412.RSAG_00752	0.0	1010.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NMLHFLOH_00286	1121115.AXVN01000006_gene2131	1.54e-291	796.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
NMLHFLOH_00287	1121115.AXVN01000006_gene2130	1.23e-187	521.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3XYUD@572511|Blautia	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
NMLHFLOH_00288	1121115.AXVN01000006_gene2129	0.0	1001.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NMLHFLOH_00289	1121115.AXVN01000006_gene2128	3.38e-251	689.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NMLHFLOH_00290	457412.RSAG_00747	1.85e-130	371.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3WM72@541000|Ruminococcaceae	186801|Clostridia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
NMLHFLOH_00291	457412.RSAG_00746	2.79e-299	825.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NMLHFLOH_00292	457412.RSAG_00744	6.99e-136	385.0	2DUTP@1|root,33S73@2|Bacteria,1US3V@1239|Firmicutes,25A29@186801|Clostridia,3WR2A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00293	457412.RSAG_00743	7.57e-211	582.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NMLHFLOH_00294	1121115.AXVN01000006_gene2123	2.12e-253	694.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NMLHFLOH_00295	457412.RSAG_00741	1.04e-306	837.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NMLHFLOH_00296	1121115.AXVN01000006_gene2121	1.09e-104	303.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NMLHFLOH_00297	1121115.AXVN01000006_gene2120	3.19e-283	774.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NMLHFLOH_00298	1121115.AXVN01000006_gene2119	6.48e-104	300.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NMLHFLOH_00299	457412.RSAG_00737	0.0	1587.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHCP@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NMLHFLOH_00300	457412.RSAG_04756	0.0	1293.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NMLHFLOH_00301	457412.RSAG_00734	4.73e-203	561.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NMLHFLOH_00302	1121115.AXVN01000006_gene2115	2.84e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
NMLHFLOH_00303	457412.RSAG_00732	4.58e-289	789.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
NMLHFLOH_00304	1121115.AXVN01000006_gene2113	9.02e-176	490.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
NMLHFLOH_00305	1121115.AXVN01000006_gene2112	3.11e-291	794.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZS4@572511|Blautia	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NMLHFLOH_00306	1121115.AXVN01000006_gene2111	1.83e-116	332.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3Y06X@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_00307	1121115.AXVN01000006_gene2110	0.0	918.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
NMLHFLOH_00308	457412.RSAG_00727	1.15e-39	131.0	COG3655@1|root,COG3655@2|Bacteria,1TU95@1239|Firmicutes,25804@186801|Clostridia,3WQZ7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NMLHFLOH_00309	457412.RSAG_00726	3.32e-56	174.0	2C1AP@1|root,33ZCD@2|Bacteria,1VYDT@1239|Firmicutes,2529X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00310	457412.RSAG_00725	1.22e-308	841.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGKB@541000|Ruminococcaceae	186801|Clostridia	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NMLHFLOH_00311	457412.RSAG_00723	0.0	1030.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
NMLHFLOH_00312	457412.RSAG_00722	2.09e-303	829.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00313	457412.RSAG_00721	0.0	1040.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NMLHFLOH_00314	1121115.AXVN01000006_gene2103	5.84e-43	141.0	2DWAP@1|root,33ZBJ@2|Bacteria,1VWWH@1239|Firmicutes,25203@186801|Clostridia,3Y23P@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NMLHFLOH_00315	457412.RSAG_00719	2.69e-256	702.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NMLHFLOH_00316	457412.RSAG_00718	3.34e-243	668.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3WSRI@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NMLHFLOH_00317	457412.RSAG_00717	2.92e-161	451.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NMLHFLOH_00318	457412.RSAG_00716	4.14e-154	433.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3WRPD@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_00319	1121115.AXVN01000061_gene488	0.0	1457.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYQH@572511|Blautia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
NMLHFLOH_00320	1121115.AXVN01000061_gene489	7.23e-85	250.0	2DRY9@1|root,33DNC@2|Bacteria,1VJXZ@1239|Firmicutes,25NY6@186801|Clostridia,3Y0SG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00321	1121115.AXVN01000061_gene490	6.17e-165	460.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia,3XZVI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NMLHFLOH_00322	457412.RSAG_00712	8.73e-191	529.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia,3WJ5M@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NMLHFLOH_00323	1121115.AXVN01000061_gene492	0.0	1597.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
NMLHFLOH_00324	457412.RSAG_00710	0.0	1827.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia,3WH9Q@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
NMLHFLOH_00325	457412.RSAG_00709	0.0	917.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NMLHFLOH_00326	1121115.AXVN01000061_gene495	2.78e-102	303.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_00327	1280698.AUJS01000060_gene919	9.82e-45	144.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24SFQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00328	1280698.AUJS01000060_gene918	1.58e-49	157.0	2E5UB@1|root,30W42@2|Bacteria,1TUDK@1239|Firmicutes,25N6K@186801|Clostridia,27X5C@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00329	272563.CD630_33460	1.87e-68	207.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia	186801|Clostridia	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NMLHFLOH_00330	272563.CD630_33450	9.51e-81	239.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,25RF1@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NMLHFLOH_00331	1121115.AXVN01000067_gene3475	0.0	900.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3Y17H@572511|Blautia	186801|Clostridia	D	Domain of unknown function DUF87	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
NMLHFLOH_00332	1121115.AXVN01000067_gene3476	0.0	932.0	COG3620@1|root,COG3620@2|Bacteria,1VR14@1239|Firmicutes,24YNP@186801|Clostridia,3Y1CW@572511|Blautia	186801|Clostridia	K	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
NMLHFLOH_00333	1121115.AXVN01000067_gene3477	1.44e-42	139.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y0EY@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00334	936375.HMPREF1152_1623	8.35e-35	125.0	2AMQT@1|root,31CM1@2|Bacteria	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00335	411902.CLOBOL_01205	3.92e-110	317.0	COG4734@1|root,COG4734@2|Bacteria,1VHFX@1239|Firmicutes,24QQM@186801|Clostridia,221Q5@1506553|Lachnoclostridium	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NMLHFLOH_00336	272563.CD630_33400	3.35e-116	332.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25QZD@186804|Peptostreptococcaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NMLHFLOH_00337	272563.CD630_33390	1.38e-89	262.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,25RAZ@186804|Peptostreptococcaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
NMLHFLOH_00338	1121115.AXVN01000067_gene3481	0.0	1575.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,3Y19W@572511|Blautia	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NMLHFLOH_00339	411459.RUMOBE_00894	0.0	1229.0	COG5602@1|root,COG5602@2|Bacteria,1UJ7A@1239|Firmicutes,25EXP@186801|Clostridia,3Y18X@572511|Blautia	186801|Clostridia	B	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00340	658086.HMPREF0994_05170	2.03e-226	625.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27M4A@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Lysozyme-like	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
NMLHFLOH_00341	658086.HMPREF0994_05171	2.14e-205	569.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27KG9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NMLHFLOH_00342	1121115.AXVN01000173_gene3957	1.92e-131	373.0	COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,24QCN@186801|Clostridia,3Y0RR@572511|Blautia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
NMLHFLOH_00343	272563.CD630_33310	7.76e-168	468.0	28IFW@1|root,2Z8HG@2|Bacteria,1UNS6@1239|Firmicutes,24AB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CBAH
NMLHFLOH_00344	411459.RUMOBE_00902	1.51e-69	211.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,24I1Y@186801|Clostridia,3Y1T1@572511|Blautia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_00345	1121115.AXVN01000141_gene2379	1.9e-96	280.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,3XZY1@572511|Blautia	186801|Clostridia	K	COG NOG16920 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NMLHFLOH_00346	1121115.AXVN01000141_gene2380	2.56e-50	159.0	2AJW5@1|root,32RUV@2|Bacteria,1VA55@1239|Firmicutes,24NMK@186801|Clostridia,3Y1TF@572511|Blautia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NMLHFLOH_00347	1121115.AXVN01000141_gene2384	2.06e-38	128.0	2ARET@1|root,31GQW@2|Bacteria,1TUXE@1239|Firmicutes,25NXF@186801|Clostridia,3Y0Q5@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
NMLHFLOH_00348	272563.CD630_33260	5.51e-284	776.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NMLHFLOH_00349	457412.RSAG_01615	0.0	1054.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NMLHFLOH_00350	457412.RSAG_01616	0.0	1671.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NMLHFLOH_00351	457412.RSAG_01617	0.0	911.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3WHXK@541000|Ruminococcaceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NMLHFLOH_00353	457412.RSAG_01618	3.05e-160	448.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3WIGB@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NMLHFLOH_00354	1121115.AXVN01000018_gene63	5.1e-43	142.0	2EC7P@1|root,33668@2|Bacteria,1VHK0@1239|Firmicutes,24R0C@186801|Clostridia,3Y0UW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00355	457412.RSAG_01620	1.01e-253	695.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3WGJ9@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
NMLHFLOH_00356	1121115.AXVN01000018_gene61	0.0	1269.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
NMLHFLOH_00357	1121115.AXVN01000018_gene60	1.37e-84	251.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
NMLHFLOH_00358	1121115.AXVN01000018_gene59	5.62e-69	208.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
NMLHFLOH_00359	1121115.AXVN01000018_gene58	2.16e-129	368.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
NMLHFLOH_00360	457412.RSAG_01625	0.0	1171.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
NMLHFLOH_00361	1121115.AXVN01000018_gene56	0.0	911.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
NMLHFLOH_00362	1121115.AXVN01000018_gene55	3.03e-134	381.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
NMLHFLOH_00363	457412.RSAG_01628	4.47e-145	411.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WRJN@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
NMLHFLOH_00364	1121115.AXVN01000018_gene53	0.0	1160.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NMLHFLOH_00365	1121115.AXVN01000018_gene52	1.45e-176	493.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,3Y1I1@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
NMLHFLOH_00366	1121115.AXVN01000018_gene51	0.0	1603.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
NMLHFLOH_00367	1121115.AXVN01000018_gene50	1.78e-145	409.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
NMLHFLOH_00368	457412.RSAG_01633	3.1e-137	388.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3WI1I@541000|Ruminococcaceae	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NMLHFLOH_00369	1121115.AXVN01000018_gene48	5.73e-136	385.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y15Q@572511|Blautia	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
NMLHFLOH_00370	1121115.AXVN01000018_gene47	1.02e-258	711.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NMLHFLOH_00371	1121115.AXVN01000018_gene46	0.0	1529.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
NMLHFLOH_00372	1121115.AXVN01000018_gene45	3.16e-232	639.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3Y1G9@572511|Blautia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
NMLHFLOH_00373	457412.RSAG_01638	1.56e-254	697.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
NMLHFLOH_00374	457412.RSAG_01639	1.11e-263	722.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3WJ42@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
NMLHFLOH_00375	1121115.AXVN01000018_gene42	8.76e-96	280.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NMLHFLOH_00376	457412.RSAG_01641	0.0	910.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NMLHFLOH_00377	1121115.AXVN01000018_gene40	6.89e-185	514.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NMLHFLOH_00378	457412.RSAG_01643	1.82e-102	296.0	COG2258@1|root,COG2258@2|Bacteria,1UIYW@1239|Firmicutes,25FCC@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
NMLHFLOH_00379	457412.RSAG_01644	1.95e-109	315.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NMLHFLOH_00380	457412.RSAG_01645	1.44e-109	315.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3WJ9J@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
NMLHFLOH_00381	457412.RSAG_01646	0.0	1318.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NMLHFLOH_00382	457412.RSAG_01648	7.82e-97	281.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3WKYJ@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NMLHFLOH_00383	457412.RSAG_01649	8.68e-129	365.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NMLHFLOH_00384	1121115.AXVN01000018_gene19	7.39e-53	168.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes,250D1@186801|Clostridia,3Y0U5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00385	457412.RSAG_01651	3.07e-240	660.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NMLHFLOH_00386	1121115.AXVN01000018_gene17	3.53e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NMLHFLOH_00387	1121115.AXVN01000018_gene16	3.14e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NMLHFLOH_00388	1121115.AXVN01000018_gene15	3.32e-119	340.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NMLHFLOH_00389	1121115.AXVN01000018_gene14	1.44e-38	129.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NMLHFLOH_00390	1121115.AXVN01000018_gene13	3.62e-35	120.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3Y0JI@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
NMLHFLOH_00391	469617.FUAG_01756	3.74e-43	172.0	COG2199@1|root,COG2199@2|Bacteria,37B22@32066|Fusobacteria	32066|Fusobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NMLHFLOH_00394	1121115.AXVN01000121_gene2849	2.41e-178	496.0	COG1028@1|root,COG1028@2|Bacteria,1V2KA@1239|Firmicutes,24GZZ@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NMLHFLOH_00395	1121115.AXVN01000121_gene2848	0.0	1149.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NMLHFLOH_00396	457412.RSAG_01659	1.63e-281	769.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	licD	-	-	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	3.A.1.10	-	-	LicD
NMLHFLOH_00397	457412.RSAG_01660	0.0	1548.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKER@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NMLHFLOH_00398	457412.RSAG_01661	1.91e-316	861.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,1V3KY@1239|Firmicutes,24BKY@186801|Clostridia,3WIHC@541000|Ruminococcaceae	186801|Clostridia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GFO_IDH_MocA
NMLHFLOH_00399	457412.RSAG_03495	0.0	867.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	ko:K13663	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NMLHFLOH_00400	1121115.AXVN01000147_gene3491	1.76e-185	515.0	COG0463@1|root,COG0463@2|Bacteria,1TSPS@1239|Firmicutes,25FHJ@186801|Clostridia,3Y1C1@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NMLHFLOH_00401	1121115.AXVN01000147_gene3490	0.0	924.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3XZJ0@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NMLHFLOH_00402	457412.RSAG_01664	5.79e-251	691.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NMLHFLOH_00403	457412.RSAG_01665	2.08e-265	727.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NMLHFLOH_00404	457412.RSAG_01666	3.7e-127	363.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WJUS@541000|Ruminococcaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NMLHFLOH_00405	457412.RSAG_01667	0.0	1004.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NMLHFLOH_00406	1121115.AXVN01000164_gene904	1.39e-142	403.0	COG5012@1|root,COG5012@2|Bacteria,1VSJU@1239|Firmicutes,24XK2@186801|Clostridia,3Y145@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NMLHFLOH_00407	457412.RSAG_01670	2.61e-133	377.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NMLHFLOH_00408	1121115.AXVN01000014_gene1248	0.0	1112.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NMLHFLOH_00409	1121115.AXVN01000014_gene1247	5.21e-138	391.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NMLHFLOH_00410	1121115.AXVN01000014_gene1246	2.32e-194	539.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3Y0ZA@572511|Blautia	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NMLHFLOH_00411	1121115.AXVN01000014_gene1245	2.4e-268	732.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NMLHFLOH_00412	1121115.AXVN01000014_gene1244	1.35e-211	585.0	COG2367@1|root,COG2367@2|Bacteria,1VSGY@1239|Firmicutes,24XQF@186801|Clostridia,3XZU7@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
NMLHFLOH_00413	1121115.AXVN01000014_gene1243	4.43e-224	618.0	2BADS@1|root,323U8@2|Bacteria,1VTZ8@1239|Firmicutes,24ZP1@186801|Clostridia,3Y1JU@572511|Blautia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00414	457412.RSAG_01677	5.04e-20	83.6	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
NMLHFLOH_00415	1121115.AXVN01000014_gene1241	6.39e-283	771.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
NMLHFLOH_00416	1122915.AUGY01000096_gene3683	5.74e-205	598.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,4HARI@91061|Bacilli,26SRJ@186822|Paenibacillaceae	91061|Bacilli	G	beta-galactosidase	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NMLHFLOH_00417	1345697.M493_09710	5.38e-226	653.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli,1WEKS@129337|Geobacillus	91061|Bacilli	G	Fibronectin type III-like domain	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_00418	1321778.HMPREF1982_00900	4.06e-143	415.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,267VT@186813|unclassified Clostridiales	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
NMLHFLOH_00419	1391647.AVSV01000003_gene1453	1.15e-225	637.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
NMLHFLOH_00420	941824.TCEL_02096	5.78e-89	278.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,36DIE@31979|Clostridiaceae	186801|Clostridia	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NMLHFLOH_00421	1235800.C819_00746	1.73e-30	131.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,27IA2@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NMLHFLOH_00422	553973.CLOHYLEM_05759	1.08e-103	315.0	COG2972@1|root,COG2972@2|Bacteria,1TRKI@1239|Firmicutes,24B7C@186801|Clostridia,21XPV@1506553|Lachnoclostridium	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
NMLHFLOH_00423	1195236.CTER_4128	1.97e-112	351.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TV2J@1239|Firmicutes,249HW@186801|Clostridia,3WHT0@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_00424	457412.RSAG_01679	4.19e-202	559.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3WHMV@541000|Ruminococcaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
NMLHFLOH_00425	457412.RSAG_01680	6.62e-232	643.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,3WI4B@541000|Ruminococcaceae	186801|Clostridia	O	DnaJ molecular chaperone homology domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
NMLHFLOH_00426	457412.RSAG_01681	1.34e-108	312.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NMLHFLOH_00427	457412.RSAG_01682	3.04e-105	304.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NMLHFLOH_00428	518637.EUBIFOR_00452	5.84e-261	718.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,3VQ1Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14
NMLHFLOH_00429	1121115.AXVN01000014_gene1222	5.55e-211	583.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3Y0D3@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
NMLHFLOH_00430	1121115.AXVN01000014_gene1221	6.21e-147	413.0	COG0572@1|root,COG0572@2|Bacteria,1V1DZ@1239|Firmicutes,24FY8@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PRK
NMLHFLOH_00431	1121115.AXVN01000014_gene1220	2.04e-85	256.0	298ZI@1|root,2ZW3A@2|Bacteria,1V7FU@1239|Firmicutes,24ID8@186801|Clostridia,3Y0E1@572511|Blautia	186801|Clostridia	S	ECF transporter, substrate-specific component	-	-	-	ko:K16788	-	-	-	-	ko00000,ko02000	2.A.88.5	-	-	ECF_trnsprt
NMLHFLOH_00432	1121115.AXVN01000014_gene1219	0.0	1021.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,3XYNS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
NMLHFLOH_00433	1121115.AXVN01000014_gene1218	3.69e-197	548.0	COG0149@1|root,COG0149@2|Bacteria,1UY0I@1239|Firmicutes,248YC@186801|Clostridia,3XZDR@572511|Blautia	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
NMLHFLOH_00434	1121115.AXVN01000014_gene1217	5.13e-147	417.0	COG0730@1|root,COG0730@2|Bacteria,1VBCY@1239|Firmicutes,24Q6R@186801|Clostridia	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
NMLHFLOH_00435	1121115.AXVN01000014_gene1216	4.41e-269	737.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZJA@572511|Blautia	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NMLHFLOH_00436	1121115.AXVN01000014_gene1215	1.21e-265	728.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3Y04K@572511|Blautia	186801|Clostridia	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NMLHFLOH_00437	1121115.AXVN01000014_gene1214	1.64e-199	552.0	COG0363@1|root,COG0363@2|Bacteria,1TQK7@1239|Firmicutes,24CQ8@186801|Clostridia,3Y0DM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	-
NMLHFLOH_00438	1121115.AXVN01000014_gene1213	2.87e-160	455.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NMLHFLOH_00439	1121115.AXVN01000014_gene1212	3.94e-249	684.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_00440	1121115.AXVN01000014_gene1211	1.62e-253	695.0	COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,24BTJ@186801|Clostridia,3Y0PU@572511|Blautia	186801|Clostridia	M	SIS domain	agaS	-	2.6.1.16	ko:K00820,ko:K02082	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
NMLHFLOH_00441	1121115.AXVN01000014_gene1210	1.08e-209	578.0	COG0191@1|root,COG0191@2|Bacteria,1U8WS@1239|Firmicutes,24DIF@186801|Clostridia,3Y2BP@572511|Blautia	186801|Clostridia	H	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
NMLHFLOH_00442	1121115.AXVN01000014_gene1209	1.42e-225	624.0	COG1609@1|root,COG1609@2|Bacteria,1V4TW@1239|Firmicutes,24HIR@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_00443	1121115.AXVN01000014_gene1208	1.51e-236	651.0	COG0715@1|root,COG0715@2|Bacteria,1TRET@1239|Firmicutes,25M8E@186801|Clostridia,3Y0VW@572511|Blautia	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
NMLHFLOH_00444	1121115.AXVN01000014_gene1207	4.15e-188	522.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3Y02Z@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NMLHFLOH_00445	1121115.AXVN01000014_gene1206	1.22e-174	488.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3Y0M7@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NMLHFLOH_00446	1121115.AXVN01000014_gene1205	1.78e-280	766.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZ4D@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NMLHFLOH_00447	1121115.AXVN01000014_gene1204	1.84e-118	340.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3XZUW@572511|Blautia	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NMLHFLOH_00448	1121115.AXVN01000014_gene1203	4.39e-127	362.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,3XZU9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NMLHFLOH_00449	1121115.AXVN01000014_gene1202	8.97e-252	690.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_00450	457412.RSAG_01683	0.0	2013.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WSRP@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NMLHFLOH_00451	457412.RSAG_01684	5.9e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3WJKJ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
NMLHFLOH_00452	457412.RSAG_01685	8.79e-208	575.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
NMLHFLOH_00453	457412.RSAG_01686	3.88e-316	860.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3WMKQ@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_00454	457412.RSAG_01687	5.17e-129	367.0	2BXQ3@1|root,2ZCWE@2|Bacteria,1V3E8@1239|Firmicutes,24GTI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00455	457412.RSAG_01688	5.06e-209	579.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3WM59@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_00456	1121115.AXVN01000014_gene1195	2.13e-205	569.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3XZBQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NMLHFLOH_00457	1121115.AXVN01000014_gene1194	4.47e-31	108.0	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00458	457412.RSAG_01691	1.78e-283	775.0	COG0526@1|root,COG0526@2|Bacteria,1TSFN@1239|Firmicutes,24DAS@186801|Clostridia	186801|Clostridia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NMLHFLOH_00459	457412.RSAG_01176	1.19e-256	739.0	COG0419@1|root,COG0420@1|root,COG0419@2|Bacteria,COG0420@2|Bacteria,1TP6S@1239|Firmicutes,24BY3@186801|Clostridia	186801|Clostridia	L	Calcineurin-like phosphoesterase	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Metallophos
NMLHFLOH_00460	457412.RSAG_04664	8.02e-89	269.0	28JTW@1|root,2Z9J1@2|Bacteria,1UIV9@1239|Firmicutes,25FDE@186801|Clostridia	186801|Clostridia	S	Phage replisome organizer, N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
NMLHFLOH_00461	457412.RSAG_04666	2.94e-184	511.0	COG0286@1|root,COG0286@2|Bacteria,1V4NI@1239|Firmicutes,24HNX@186801|Clostridia,3WIWS@541000|Ruminococcaceae	186801|Clostridia	V	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
NMLHFLOH_00462	457412.RSAG_01173	2.24e-162	456.0	28KDZ@1|root,32WQ4@2|Bacteria,1VB19@1239|Firmicutes,24PQV@186801|Clostridia	186801|Clostridia	S	PcfK-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfK
NMLHFLOH_00463	457412.RSAG_01172	0.0	1460.0	28KSN@1|root,2ZA9Z@2|Bacteria,1V06Q@1239|Firmicutes,24GKD@186801|Clostridia	186801|Clostridia	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
NMLHFLOH_00464	457412.RSAG_01171	8.1e-36	121.0	2EH1D@1|root,33ATD@2|Bacteria,1VPT3@1239|Firmicutes,24VW3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00465	457412.RSAG_01170	4.23e-49	155.0	2E5XQ@1|root,330MJ@2|Bacteria,1VJNW@1239|Firmicutes,24T4D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00466	457412.RSAG_01169	2.29e-49	157.0	2E55R@1|root,32ZYM@2|Bacteria,1VGWX@1239|Firmicutes,24S5V@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00467	457412.RSAG_01168	5.39e-71	217.0	COG3331@1|root,COG3331@2|Bacteria,1V3KI@1239|Firmicutes,24N80@186801|Clostridia,3WJ5C@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	-	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
NMLHFLOH_00468	1235793.C809_02201	2.05e-91	284.0	COG0592@1|root,COG0592@2|Bacteria,1VSYS@1239|Firmicutes,24XGN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol3_beta_3
NMLHFLOH_00474	457412.RSAG_01163	1.3e-65	199.0	2CPH5@1|root,32SJ4@2|Bacteria,1VCE2@1239|Firmicutes,24NY8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00475	457412.RSAG_01162	2.56e-111	320.0	2EGZP@1|root,33ART@2|Bacteria,1VKPB@1239|Firmicutes,24VDH@186801|Clostridia	186801|Clostridia	S	YopX protein	-	-	-	-	-	-	-	-	-	-	-	-	YopX
NMLHFLOH_00478	476272.RUMHYD_03348	4.45e-08	56.6	2DF89@1|root,2ZQW8@2|Bacteria,1W214@1239|Firmicutes,254S1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00479	1280692.AUJL01000009_gene2996	5.83e-14	66.2	2BB9Y@1|root,324SP@2|Bacteria,1UQZ4@1239|Firmicutes,24VBZ@186801|Clostridia,36PCV@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00483	457412.RSAG_01155	4.22e-45	145.0	2EU67@1|root,33MNT@2|Bacteria,1VFUR@1239|Firmicutes,24SZQ@186801|Clostridia,3WSBT@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00485	457412.RSAG_01153	2.24e-120	345.0	2EIUX@1|root,33CK8@2|Bacteria,1VM47@1239|Firmicutes,24QI2@186801|Clostridia,3WMIV@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00486	457412.RSAG_01152	2.1e-305	835.0	COG0591@1|root,COG0591@2|Bacteria,1UZR7@1239|Firmicutes,24DMN@186801|Clostridia,3WN41@541000|Ruminococcaceae	186801|Clostridia	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
NMLHFLOH_00487	457412.RSAG_01151	6.17e-192	531.0	COG0175@1|root,COG0175@2|Bacteria,1TSCZ@1239|Firmicutes,24B7H@186801|Clostridia	186801|Clostridia	EH	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
NMLHFLOH_00488	457412.RSAG_01150	3.74e-134	382.0	COG1475@1|root,COG1475@2|Bacteria,1V4GC@1239|Firmicutes,24I91@186801|Clostridia,3WJGU@541000|Ruminococcaceae	186801|Clostridia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
NMLHFLOH_00489	457412.RSAG_01149	1.56e-94	284.0	COG3969@1|root,COG3969@2|Bacteria,1TPCD@1239|Firmicutes,24DNV@186801|Clostridia,3WJMS@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoadenosine phosphosulfate reductase family	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
NMLHFLOH_00490	457412.RSAG_04668	3.92e-140	399.0	COG5484@1|root,COG5484@2|Bacteria,1V58P@1239|Firmicutes,25CX0@186801|Clostridia,3WMPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_terminase
NMLHFLOH_00491	457412.RSAG_04669	0.0	978.0	COG0507@1|root,COG0507@2|Bacteria,1TQWH@1239|Firmicutes,24A8I@186801|Clostridia	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00492	457412.RSAG_01145	0.0	902.0	COG4383@1|root,COG4383@2|Bacteria,1TS7T@1239|Firmicutes,24CCB@186801|Clostridia,3WNCM@541000|Ruminococcaceae	186801|Clostridia	S	Mu-like prophage protein gp29	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00493	457412.RSAG_01144	5.76e-215	594.0	2DKDU@1|root,3098H@2|Bacteria,1V5QM@1239|Firmicutes,24I5X@186801|Clostridia,3WPW6@541000|Ruminococcaceae	186801|Clostridia	S	Phage Mu protein F like protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Mu_F
NMLHFLOH_00494	457412.RSAG_01143	1.04e-93	275.0	2BWN7@1|root,32QZT@2|Bacteria,1V8V6@1239|Firmicutes,24KHY@186801|Clostridia,3WPZ5@541000|Ruminococcaceae	186801|Clostridia	S	Putative phage serine protease XkdF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S78_2
NMLHFLOH_00495	457412.RSAG_01142	1.33e-257	711.0	28IAC@1|root,2Z8CY@2|Bacteria,1TT1K@1239|Firmicutes,24D6R@186801|Clostridia,3WPRD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00496	457412.RSAG_01141	4.12e-90	265.0	2BAIK@1|root,323Z8@2|Bacteria,1V6P4@1239|Firmicutes,24M0G@186801|Clostridia,3WR0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00497	457412.RSAG_01140	3.37e-249	683.0	28HVH@1|root,2Z81R@2|Bacteria,1UZ5D@1239|Firmicutes,2499J@186801|Clostridia,3WP25@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00498	457412.RSAG_01139	3e-93	273.0	2F5XU@1|root,33YGH@2|Bacteria,1VYCB@1239|Firmicutes,252C4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00499	457412.RSAG_01138	1.67e-99	288.0	2DZM7@1|root,32VDP@2|Bacteria,1VCFC@1239|Firmicutes,24PP9@186801|Clostridia,3WQAZ@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00500	457412.RSAG_01137	3.12e-79	235.0	2EVRV@1|root,33P5T@2|Bacteria,1VKSV@1239|Firmicutes,24V2N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00501	457412.RSAG_01136	3.52e-71	215.0	2EVMB@1|root,33P1C@2|Bacteria,1VNEE@1239|Firmicutes,24UP8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00502	457412.RSAG_01135	1.51e-39	133.0	2EF2C@1|root,338VE@2|Bacteria,1VET9@1239|Firmicutes,24SX4@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5026)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5026
NMLHFLOH_00503	457412.RSAG_01134	3.84e-181	507.0	29E2B@1|root,30109@2|Bacteria,1V4I5@1239|Firmicutes,24I6Y@186801|Clostridia,3WQ4G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00505	457412.RSAG_01132	3.63e-251	699.0	28IGV@1|root,2Z8I6@2|Bacteria,1TP1Y@1239|Firmicutes,24AS0@186801|Clostridia,3WNDK@541000|Ruminococcaceae	186801|Clostridia	S	Phage tail sheath protein subtilisin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_sheath_1,Phage_sheath_1C,Phage_sheath_1N
NMLHFLOH_00506	457412.RSAG_01131	1.43e-83	249.0	2AEG2@1|root,314B5@2|Bacteria,1VGQ1@1239|Firmicutes,24SIG@186801|Clostridia,3WQM9@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00507	457412.RSAG_01130	1.19e-84	254.0	2CG00@1|root,32S2V@2|Bacteria,1VCP2@1239|Firmicutes,24Q0X@186801|Clostridia,3WQYB@541000|Ruminococcaceae	186801|Clostridia	S	Phage XkdN-like tail assembly chaperone protein, TAC	-	-	-	-	-	-	-	-	-	-	-	-	Phage_TAC_5
NMLHFLOH_00508	457412.RSAG_01128	0.0	2395.0	COG3064@1|root,COG5283@1|root,COG3064@2|Bacteria,COG5283@2|Bacteria,1UHQM@1239|Firmicutes,25E9Q@186801|Clostridia,3WSPK@541000|Ruminococcaceae	186801|Clostridia	M	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,PhageMin_Tail
NMLHFLOH_00509	457412.RSAG_01127	3.61e-151	426.0	COG1652@1|root,COG1652@2|Bacteria,1V1BA@1239|Firmicutes,24REC@186801|Clostridia,3WQJD@541000|Ruminococcaceae	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NMLHFLOH_00510	457412.RSAG_01126	3.81e-293	801.0	COG3500@1|root,COG3500@2|Bacteria,1U3ZB@1239|Firmicutes,2595N@186801|Clostridia,3WPNW@541000|Ruminococcaceae	186801|Clostridia	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00511	457412.RSAG_01125	2.14e-68	207.0	2EM0X@1|root,32612@2|Bacteria,1US0A@1239|Firmicutes,259Y2@186801|Clostridia,3WQW6@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00512	457412.RSAG_04670	1.47e-105	304.0	2CDGF@1|root,31F2E@2|Bacteria,1V9UN@1239|Firmicutes,24N4Q@186801|Clostridia,3WQ56@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2634
NMLHFLOH_00513	457412.RSAG_01122	8.83e-265	726.0	COG3299@1|root,COG3299@2|Bacteria,1TQZU@1239|Firmicutes,249WP@186801|Clostridia,3WKEW@541000|Ruminococcaceae	186801|Clostridia	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
NMLHFLOH_00514	457412.RSAG_01121	4.94e-138	395.0	COG4385@1|root,COG4385@2|Bacteria,1VDJ6@1239|Firmicutes,24P8H@186801|Clostridia,3WQ4A@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2313
NMLHFLOH_00515	457412.RSAG_01120	3.07e-67	205.0	2EAW6@1|root,334XF@2|Bacteria,1VINA@1239|Firmicutes	1239|Firmicutes	S	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3751
NMLHFLOH_00520	457412.RSAG_01114	0.0	871.0	COG0641@1|root,COG0641@2|Bacteria,1TRN3@1239|Firmicutes,24BV6@186801|Clostridia,3WN4F@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
NMLHFLOH_00521	457412.RSAG_01113	4.71e-153	432.0	2DDPW@1|root,2ZIUM@2|Bacteria,1W588@1239|Firmicutes,255Q6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00522	457412.RSAG_01112	6.02e-61	212.0	2DKX6@1|root,30QMZ@2|Bacteria,1V66W@1239|Firmicutes,24HHF@186801|Clostridia,3WQKA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00525	1160721.RBI_I01568	3.6e-65	216.0	COG3344@1|root,COG3344@2|Bacteria,1UZGP@1239|Firmicutes,24BRP@186801|Clostridia,3WIKU@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NMLHFLOH_00528	457412.RSAG_04673	3.73e-33	114.0	2CEZI@1|root,2ZUS5@2|Bacteria,1W2NQ@1239|Firmicutes,255GR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00529	411459.RUMOBE_01081	1.48e-39	134.0	2C59M@1|root,32WN6@2|Bacteria,1VBWI@1239|Firmicutes,24W9I@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00530	457412.RSAG_01108	6.46e-52	165.0	2E9QN@1|root,333X0@2|Bacteria,1VJYI@1239|Firmicutes,24S7V@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00531	457412.RSAG_01106	5.59e-61	188.0	2E88Y@1|root,332MW@2|Bacteria,1VGHP@1239|Firmicutes,24RF1@186801|Clostridia,3WMTA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00532	411459.RUMOBE_01085	1.31e-84	275.0	2DN8Y@1|root,32W5U@2|Bacteria,1VBWS@1239|Firmicutes,24PRC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00534	608534.GCWU000341_01782	1.4e-05	52.8	COG2944@1|root,COG2944@2|Bacteria,1VKXX@1239|Firmicutes,24V85@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NMLHFLOH_00535	411470.RUMGNA_03785	8.4e-14	71.2	2DCC6@1|root,2ZDN5@2|Bacteria,1W4KE@1239|Firmicutes,254IB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00536	888727.HMPREF9092_0491	8.17e-11	61.2	COG2944@1|root,COG2944@2|Bacteria,1VKXX@1239|Firmicutes,24V85@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NMLHFLOH_00537	457412.RSAG_01104	2.35e-47	152.0	COG3655@1|root,COG3655@2|Bacteria,1VHK7@1239|Firmicutes,24R05@186801|Clostridia,3WM36@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
NMLHFLOH_00538	457412.RSAG_01102	8.13e-181	508.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia,3WGKY@541000|Ruminococcaceae	186801|Clostridia	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
NMLHFLOH_00540	457412.RSAG_01100	5.59e-37	124.0	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,HTH_26,HTH_3
NMLHFLOH_00541	457412.RSAG_04674	0.0	1122.0	COG0515@1|root,COG5263@1|root,COG0515@2|Bacteria,COG5263@2|Bacteria,1V47G@1239|Firmicutes,25FXW@186801|Clostridia,3WKMM@541000|Ruminococcaceae	186801|Clostridia	KLT	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
NMLHFLOH_00542	457412.RSAG_01097	5.25e-313	854.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3WIX2@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NMLHFLOH_00543	457412.RSAG_01096	1.3e-200	555.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NMLHFLOH_00544	1121115.AXVN01000001_gene1074	1.28e-131	373.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,3Y053@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_00545	457412.RSAG_01094	6.8e-42	141.0	2F54G@1|root,33XRK@2|Bacteria,1VVDU@1239|Firmicutes,250QM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00546	1121115.AXVN01000001_gene1072	4.01e-235	647.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
NMLHFLOH_00547	457412.RSAG_01092	2.95e-301	822.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NMLHFLOH_00548	1121115.AXVN01000001_gene1070	5.93e-261	715.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
NMLHFLOH_00549	1121115.AXVN01000001_gene1069	0.0	1375.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia	186801|Clostridia	J	translation elongation factor G	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NMLHFLOH_00550	457412.RSAG_01089	0.0	1649.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NMLHFLOH_00551	1121115.AXVN01000001_gene1067	8.05e-312	851.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00552	1121115.AXVN01000001_gene1066	0.0	1027.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
NMLHFLOH_00553	457412.RSAG_01086	0.0	1149.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3WG7T@541000|Ruminococcaceae	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NMLHFLOH_00554	457412.RSAG_01085	4.66e-200	555.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NMLHFLOH_00555	457412.RSAG_01084	7.36e-55	171.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NMLHFLOH_00556	457412.RSAG_01083	8.08e-140	395.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NMLHFLOH_00557	1121115.AXVN01000001_gene1061	1.63e-47	155.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
NMLHFLOH_00558	1121115.AXVN01000001_gene1060	0.0	878.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NMLHFLOH_00559	1121115.AXVN01000001_gene1059	7.41e-120	343.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NMLHFLOH_00560	1121115.AXVN01000001_gene1058	1.84e-98	288.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NMLHFLOH_00561	1121115.AXVN01000001_gene1057	5.18e-55	172.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00562	1121115.AXVN01000001_gene1056	5.64e-79	235.0	2BB22@1|root,324I6@2|Bacteria,1UQT3@1239|Firmicutes,258J6@186801|Clostridia,3Y0Q8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00563	457412.RSAG_01076	3.69e-33	114.0	2FGS5@1|root,348MK@2|Bacteria,1W0U5@1239|Firmicutes,2540A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00564	1121115.AXVN01000001_gene1054	1.1e-29	109.0	2F3CT@1|root,33W6S@2|Bacteria,1VVCN@1239|Firmicutes,250TA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00565	457412.RSAG_01073	4.11e-204	579.0	COG5263@1|root,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3WQ86@541000|Ruminococcaceae	186801|Clostridia	M	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
NMLHFLOH_00566	1121115.AXVN01000001_gene1052	9.11e-302	822.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NMLHFLOH_00567	457412.RSAG_01071	0.0	1625.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NMLHFLOH_00568	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NMLHFLOH_00569	1121115.AXVN01000001_gene1049	0.0	1053.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NMLHFLOH_00570	457412.RSAG_01068	9.92e-285	778.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00571	457412.RSAG_01067	3.12e-251	689.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
NMLHFLOH_00572	457412.RSAG_01066	4.47e-199	551.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJK2@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NMLHFLOH_00573	457412.RSAG_01065	1.89e-184	513.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJM6@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
NMLHFLOH_00574	457412.RSAG_01064	1.94e-129	368.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
NMLHFLOH_00575	1121115.AXVN01000001_gene1043	1.63e-190	528.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NMLHFLOH_00576	1121115.AXVN01000001_gene1042	4.9e-303	825.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZ3I@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00577	457412.RSAG_01060	1.14e-180	503.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
NMLHFLOH_00578	457412.RSAG_01059	3.87e-208	576.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia,3WJ83@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_00579	457412.RSAG_01058	1.36e-206	570.0	COG1082@1|root,COG1082@2|Bacteria,1TT50@1239|Firmicutes,248RM@186801|Clostridia,3WN3B@541000|Ruminococcaceae	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NMLHFLOH_00580	457412.RSAG_01057	0.0	1268.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae	186801|Clostridia	C	NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NMLHFLOH_00581	457412.RSAG_01056	5.72e-206	570.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WI65@541000|Ruminococcaceae	186801|Clostridia	C	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NMLHFLOH_00582	457412.RSAG_01055	7.66e-273	748.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia,3WKIP@541000|Ruminococcaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NMLHFLOH_00583	457412.RSAG_01054	0.0	873.0	COG0659@1|root,COG0659@2|Bacteria,1TT9Y@1239|Firmicutes,249RX@186801|Clostridia,3WSRN@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	BenE
NMLHFLOH_00584	1121115.AXVN01000019_gene172	1.95e-172	482.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3XZNE@572511|Blautia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
NMLHFLOH_00585	457412.RSAG_01041	5.33e-210	580.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NMLHFLOH_00586	457412.RSAG_01040	0.0	1330.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WJT6@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NMLHFLOH_00587	457412.RSAG_01038	0.0	920.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NMLHFLOH_00588	457412.RSAG_01037	2.8e-133	382.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia,3WJXG@541000|Ruminococcaceae	186801|Clostridia	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
NMLHFLOH_00589	1121115.AXVN01000019_gene167	7.37e-54	171.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NMLHFLOH_00590	1121115.AXVN01000019_gene166	3.46e-265	727.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
NMLHFLOH_00591	457412.RSAG_01034	0.0	924.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NMLHFLOH_00592	457412.RSAG_01033	0.0	867.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NMLHFLOH_00593	1121115.AXVN01000019_gene163	3.11e-145	410.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3XZMG@572511|Blautia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NMLHFLOH_00594	1121115.AXVN01000019_gene162	1.86e-210	581.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3XYNX@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
NMLHFLOH_00595	1121115.AXVN01000019_gene161	4.23e-247	679.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
NMLHFLOH_00596	1121115.AXVN01000019_gene160	7.27e-104	308.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3XZY8@572511|Blautia	186801|Clostridia	GM	Psort location Cytoplasmic, score 8.87	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NMLHFLOH_00597	478749.BRYFOR_09281	7.07e-76	235.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24G4J@186801|Clostridia	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	Wzz
NMLHFLOH_00598	478749.BRYFOR_09282	3.61e-86	265.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia	186801|Clostridia	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,CbiA
NMLHFLOH_00599	478749.BRYFOR_09283	7.15e-119	353.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NMLHFLOH_00602	1121115.AXVN01000044_gene2027	3.4e-73	223.0	COG0250@1|root,COG0250@2|Bacteria,1V3BF@1239|Firmicutes,24G49@186801|Clostridia	186801|Clostridia	K	Transcription termination	-	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NMLHFLOH_00603	457412.RSAG_00021	5.03e-276	762.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
NMLHFLOH_00604	457412.RSAG_00022	1.86e-197	552.0	COG0614@1|root,COG5386@1|root,COG0614@2|Bacteria,COG5386@2|Bacteria,1UYC0@1239|Firmicutes,24D7G@186801|Clostridia,3WSRF@541000|Ruminococcaceae	186801|Clostridia	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00605	457412.RSAG_00023	2.96e-285	779.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NMLHFLOH_00606	1121115.AXVN01000002_gene1388	6.03e-226	624.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3Y151@572511|Blautia	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NMLHFLOH_00607	457412.RSAG_00025	6.32e-274	749.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHJY@541000|Ruminococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
NMLHFLOH_00608	1121115.AXVN01000002_gene1390	3.21e-178	496.0	COG0463@1|root,COG0463@2|Bacteria,1TRRK@1239|Firmicutes,24CHM@186801|Clostridia,3Y03K@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NMLHFLOH_00609	1121115.AXVN01000002_gene1391	2.51e-56	175.0	2F99N@1|root,340RC@2|Bacteria,1VX34@1239|Firmicutes,257JQ@186801|Clostridia,3Y26Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00610	457412.RSAG_00028	0.0	1016.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V1JE@1239|Firmicutes,24GTB@186801|Clostridia,3WK9S@541000|Ruminococcaceae	186801|Clostridia	D	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00611	1121115.AXVN01000002_gene1393	0.0	1202.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
NMLHFLOH_00612	1121115.AXVN01000002_gene1394	7e-272	741.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,3XZ06@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
NMLHFLOH_00613	457412.RSAG_00031	2.31e-26	105.0	COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia	186801|Clostridia	Q	PFAM Collagen triple helix	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
NMLHFLOH_00614	1121115.AXVN01000002_gene1396	0.0	1038.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_00615	457412.RSAG_00033	4.17e-194	538.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3WHDE@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
NMLHFLOH_00616	1121115.AXVN01000002_gene1398	3.56e-314	856.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
NMLHFLOH_00617	1121115.AXVN01000002_gene1399	5.76e-217	600.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NMLHFLOH_00618	457412.RSAG_00036	5.29e-196	542.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3WHKS@541000|Ruminococcaceae	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
NMLHFLOH_00619	1121115.AXVN01000002_gene1401	1.89e-91	267.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
NMLHFLOH_00620	1121115.AXVN01000002_gene1402	0.0	1292.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
NMLHFLOH_00621	1121115.AXVN01000002_gene1403	5.15e-109	313.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
NMLHFLOH_00622	1121115.AXVN01000002_gene1404	9.19e-243	665.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
NMLHFLOH_00623	1121115.AXVN01000002_gene1405	8.38e-260	710.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
NMLHFLOH_00624	1121115.AXVN01000002_gene1406	1.87e-215	593.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NMLHFLOH_00625	1121115.AXVN01000002_gene1407	3.15e-163	456.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
NMLHFLOH_00626	457412.RSAG_00043	0.0	1068.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
NMLHFLOH_00627	457412.RSAG_00044	2.35e-207	572.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NMLHFLOH_00628	1121115.AXVN01000002_gene1410	7.64e-131	371.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NMLHFLOH_00629	457412.RSAG_00046	1.06e-166	466.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
NMLHFLOH_00630	1121115.AXVN01000002_gene1412	4.82e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NMLHFLOH_00631	457412.RSAG_00048	0.0	1226.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NMLHFLOH_00632	457412.RSAG_00049	0.0	1147.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WGMQ@541000|Ruminococcaceae	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
NMLHFLOH_00633	457412.RSAG_00050	0.0	901.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,3WSIQ@541000|Ruminococcaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
NMLHFLOH_00634	457412.RSAG_00051	2.54e-84	248.0	COG5341@1|root,COG5341@2|Bacteria,1UQFQ@1239|Firmicutes,25873@186801|Clostridia,3WM3Y@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
NMLHFLOH_00635	1121115.AXVN01000002_gene1417	0.0	1008.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3XZ0V@572511|Blautia	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NMLHFLOH_00636	1121115.AXVN01000002_gene1418	3.5e-218	600.0	COG0152@1|root,COG0152@2|Bacteria,1UF8J@1239|Firmicutes,25K96@186801|Clostridia,3XZ70@572511|Blautia	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NMLHFLOH_00637	457412.RSAG_00054	1.03e-240	660.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_00638	1121115.AXVN01000002_gene1420	1.11e-46	150.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3Y0MU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00639	457412.RSAG_00056	6.64e-260	711.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3WGPF@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NMLHFLOH_00640	457412.RSAG_00057	0.0	944.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3WGAN@541000|Ruminococcaceae	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydG	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NMLHFLOH_00641	1121115.AXVN01000002_gene1423	7.06e-291	794.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
NMLHFLOH_00642	1121115.AXVN01000002_gene1424	4.54e-63	192.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
NMLHFLOH_00643	457412.RSAG_00060	7.14e-39	129.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NMLHFLOH_00644	457412.RSAG_00061	3.97e-43	141.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3WKEJ@541000|Ruminococcaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NMLHFLOH_00645	457412.RSAG_00063	0.0	1421.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NMLHFLOH_00646	1410632.JHWW01000021_gene418	3.44e-11	58.5	2DRWB@1|root,33DDT@2|Bacteria,1VKGH@1239|Firmicutes,24VWG@186801|Clostridia,27PQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
NMLHFLOH_00647	457412.RSAG_00065	6.61e-110	316.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,3WM1R@541000|Ruminococcaceae	186801|Clostridia	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NMLHFLOH_00648	1121115.AXVN01000002_gene1429	2.52e-49	159.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3Y0EI@572511|Blautia	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00649	1121115.AXVN01000002_gene1430	0.0	1313.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3XYS4@572511|Blautia	186801|Clostridia	P	COG COG2217 Cation transport ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
NMLHFLOH_00650	1121115.AXVN01000002_gene1431	8.98e-86	253.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3Y0AY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NMLHFLOH_00651	457412.RSAG_00069	8.38e-46	147.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NMLHFLOH_00652	457412.RSAG_00070	0.0	1174.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NMLHFLOH_00653	1121115.AXVN01000002_gene1434	3.01e-77	230.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NMLHFLOH_00654	457412.RSAG_00072	1.47e-94	277.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3WJDB@541000|Ruminococcaceae	186801|Clostridia	S	heptaprenyl diphosphate synthase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
NMLHFLOH_00655	457412.RSAG_00073	0.0	1130.0	COG5492@1|root,COG5492@2|Bacteria,1UKHW@1239|Firmicutes,25FXE@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NMLHFLOH_00656	1121115.AXVN01000002_gene1437	1.48e-94	280.0	COG3976@1|root,COG3976@2|Bacteria,1VT26@1239|Firmicutes,25BMN@186801|Clostridia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
NMLHFLOH_00657	457412.RSAG_00075	1.15e-187	521.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
NMLHFLOH_00658	1121115.AXVN01000002_gene1439	4.56e-244	671.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3XZKQ@572511|Blautia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NMLHFLOH_00659	457412.RSAG_00077	0.0	1101.0	COG5492@1|root,COG5492@2|Bacteria,1UK32@1239|Firmicutes,25FHP@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,PBP-Tp47_a,PBP-Tp47_c
NMLHFLOH_00660	1121115.AXVN01000002_gene1441	2.2e-263	733.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3Y15H@572511|Blautia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
NMLHFLOH_00661	457412.RSAG_00079	1.35e-55	173.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia,3WKXC@541000|Ruminococcaceae	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NMLHFLOH_00662	457412.RSAG_00081	1.24e-82	244.0	2FAVS@1|root,3432X@2|Bacteria,1VXAQ@1239|Firmicutes,2520G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00663	457412.RSAG_00082	2.26e-265	732.0	COG4219@1|root,COG4219@2|Bacteria,1V0EY@1239|Firmicutes,24EI3@186801|Clostridia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NMLHFLOH_00664	1121115.AXVN01000002_gene1445	3.51e-309	843.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYZA@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NMLHFLOH_00665	1121115.AXVN01000002_gene1446	0.0	1243.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	2|Bacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NMLHFLOH_00666	1121115.AXVN01000002_gene1447	0.0	896.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XZ69@572511|Blautia	186801|Clostridia	H	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NMLHFLOH_00667	1121115.AXVN01000002_gene1448	7.15e-122	348.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
NMLHFLOH_00668	457412.RSAG_00087	5.05e-259	711.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NMLHFLOH_00669	1121115.AXVN01000002_gene1450	3.64e-47	158.0	29V65@1|root,30GJT@2|Bacteria,1UG71@1239|Firmicutes,25NFM@186801|Clostridia,3Y24B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00670	1121115.AXVN01000002_gene1451	0.0	1148.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
NMLHFLOH_00671	1121115.AXVN01000002_gene1452	3.2e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NMLHFLOH_00672	457412.RSAG_00093	0.0	926.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,3WPCY@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
NMLHFLOH_00673	457412.RSAG_00094	0.0	1254.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NMLHFLOH_00674	457412.RSAG_00095	4.13e-165	462.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3WJDP@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
NMLHFLOH_00675	457412.RSAG_00096	9.24e-288	786.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3WICU@541000|Ruminococcaceae	186801|Clostridia	J	TIGRFAM ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
NMLHFLOH_00676	1121115.AXVN01000020_gene129	3.99e-64	196.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NMLHFLOH_00677	1121115.AXVN01000020_gene128	1.58e-70	212.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
NMLHFLOH_00678	1121115.AXVN01000020_gene127	3.52e-62	190.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NMLHFLOH_00679	1121115.AXVN01000020_gene126	6.85e-315	857.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3XYJQ@572511|Blautia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
NMLHFLOH_00680	1121115.AXVN01000020_gene125	6e-60	185.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3Y0BI@572511|Blautia	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
NMLHFLOH_00681	1121115.AXVN01000020_gene124	3.59e-154	432.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3XZHC@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NMLHFLOH_00682	1121115.AXVN01000020_gene123	3.1e-143	403.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
NMLHFLOH_00683	1121115.AXVN01000020_gene122	1.23e-80	239.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NMLHFLOH_00684	1121115.AXVN01000020_gene121	4.19e-146	411.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
NMLHFLOH_00685	457412.RSAG_00105	0.0	919.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3WIPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00686	1121115.AXVN01000020_gene119	8.01e-162	453.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NMLHFLOH_00687	1121115.AXVN01000020_gene118	2.8e-107	314.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3XZSZ@572511|Blautia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NMLHFLOH_00688	457412.RSAG_00109	3.69e-180	501.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
NMLHFLOH_00689	457412.RSAG_00110	6.92e-260	712.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NMLHFLOH_00690	1121115.AXVN01000020_gene115	2.06e-119	341.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3Y0CB@572511|Blautia	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NMLHFLOH_00691	457412.RSAG_00112	8.26e-220	606.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NMLHFLOH_00692	1121115.AXVN01000020_gene113	1.58e-153	431.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
NMLHFLOH_00693	1121115.AXVN01000020_gene112	0.0	939.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NMLHFLOH_00694	1121115.AXVN01000020_gene111	3.49e-233	657.0	COG4942@1|root,COG5263@1|root,COG4942@2|Bacteria,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
NMLHFLOH_00695	1121115.AXVN01000020_gene110	6.36e-98	284.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
NMLHFLOH_00696	1121115.AXVN01000020_gene108	1.29e-258	709.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NMLHFLOH_00697	1121115.AXVN01000020_gene107	2.17e-56	175.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,3Y20U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00698	1121115.AXVN01000020_gene106	1.7e-92	270.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00699	457412.RSAG_00121	1.9e-161	452.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
NMLHFLOH_00700	1121115.AXVN01000020_gene104	4.08e-117	335.0	2C2F1@1|root,33RFH@2|Bacteria,1VSIV@1239|Firmicutes,24ZQ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00701	457412.RSAG_00123	1.35e-155	436.0	2CX3M@1|root,32T12@2|Bacteria,1VTDD@1239|Firmicutes,24Z9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00702	457412.RSAG_00124	9.76e-64	194.0	2DZYH@1|root,32VN8@2|Bacteria,1VB55@1239|Firmicutes,24P04@186801|Clostridia,3WQXJ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NMLHFLOH_00703	457412.RSAG_00125	4.54e-63	192.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3WJV4@541000|Ruminococcaceae	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
NMLHFLOH_00704	1121115.AXVN01000020_gene100	2.39e-55	172.0	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
NMLHFLOH_00705	457412.RSAG_00127	4.22e-45	145.0	2EPN8@1|root,33H8W@2|Bacteria,1VM4B@1239|Firmicutes,24VJ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00706	457412.RSAG_00129	1.69e-75	225.0	2F70J@1|root,33ZG8@2|Bacteria,1VX30@1239|Firmicutes,251WZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00707	1121115.AXVN01000020_gene97	8.37e-126	358.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia,3Y0IJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
NMLHFLOH_00708	457412.RSAG_00131	9.92e-285	778.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00709	457412.RSAG_00132	1.51e-245	678.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
NMLHFLOH_00710	457412.RSAG_00133	1.38e-59	184.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,3WJJQ@541000|Ruminococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
NMLHFLOH_00711	1121115.AXVN01000020_gene93	3.12e-178	497.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
NMLHFLOH_00712	457412.RSAG_00135	0.0	1875.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NMLHFLOH_00713	457412.RSAG_00136	8.38e-120	342.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3WJYV@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NMLHFLOH_00714	457412.RSAG_00137	5.94e-208	576.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NMLHFLOH_00715	1121115.AXVN01000020_gene89	2.96e-241	663.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NMLHFLOH_00716	1121115.AXVN01000020_gene88	2.22e-171	478.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NMLHFLOH_00717	457412.RSAG_02180	0.0	1019.0	COG1520@1|root,COG1520@2|Bacteria,1UKI6@1239|Firmicutes,25FXQ@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00718	457412.RSAG_02178	3.65e-94	275.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,3WJGS@541000|Ruminococcaceae	186801|Clostridia	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
NMLHFLOH_00719	457412.RSAG_02177	6.23e-189	527.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WM12@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
NMLHFLOH_00720	1121115.AXVN01000024_gene314	9.41e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3XYMR@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_00721	1121115.AXVN01000024_gene315	3.66e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NMLHFLOH_00722	1121115.AXVN01000024_gene316	0.0	1222.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NMLHFLOH_00723	1121115.AXVN01000024_gene317	0.0	1859.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3XYRD@572511|Blautia	186801|Clostridia	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
NMLHFLOH_00724	457412.RSAG_02171	0.0	1127.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,24YQ5@186801|Clostridia,3WGXS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,PAS
NMLHFLOH_00725	457412.RSAG_02170	5.4e-294	801.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3WGNY@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
NMLHFLOH_00726	457412.RSAG_02169	2.2e-104	301.0	COG2258@1|root,COG2258@2|Bacteria,1W5YX@1239|Firmicutes,255UB@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00727	1121115.AXVN01000022_gene1765	4.74e-305	831.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3Y0HF@572511|Blautia	186801|Clostridia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
NMLHFLOH_00728	457412.RSAG_02167	3.59e-118	338.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
NMLHFLOH_00729	1121115.AXVN01000022_gene1763	3.58e-198	548.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
NMLHFLOH_00730	457412.RSAG_02165	1.25e-240	660.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
NMLHFLOH_00731	457412.RSAG_02163	2.63e-149	419.0	COG0746@1|root,COG0746@2|Bacteria,1VA6T@1239|Firmicutes,24JG6@186801|Clostridia,3WMHP@541000|Ruminococcaceae	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NMLHFLOH_00732	457412.RSAG_02162	1.33e-143	405.0	2CKNK@1|root,306D0@2|Bacteria,1TZJW@1239|Firmicutes,2513T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00733	1121115.AXVN01000022_gene1759	2.77e-116	338.0	2F19F@1|root,33UAG@2|Bacteria,1VUX8@1239|Firmicutes,250KD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00735	457412.RSAG_02160	5.61e-98	285.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3WRW2@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NMLHFLOH_00736	457412.RSAG_02159	4.65e-180	501.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SPOR
NMLHFLOH_00737	1121115.AXVN01000022_gene1756	0.0	945.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_00738	457412.RSAG_02157	1.53e-215	596.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3WJJR@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
NMLHFLOH_00739	457412.RSAG_02156	0.0	1500.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NMLHFLOH_00740	1121115.AXVN01000022_gene1753	0.0	865.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NMLHFLOH_00741	1121115.AXVN01000022_gene1752	7.72e-194	538.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NMLHFLOH_00742	1121115.AXVN01000022_gene1751	5.26e-123	351.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3Y067@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NMLHFLOH_00743	457412.RSAG_02152	1.18e-224	618.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
NMLHFLOH_00744	457412.RSAG_02151	3.98e-230	634.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3WH6N@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NMLHFLOH_00745	457412.RSAG_02150	6.44e-18	78.2	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NMLHFLOH_00746	457412.RSAG_02149	1.16e-210	583.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3WGVA@541000|Ruminococcaceae	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
NMLHFLOH_00747	457412.RSAG_02148	1.85e-284	780.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3WGV1@541000|Ruminococcaceae	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NMLHFLOH_00748	1121115.AXVN01000022_gene1745	0.0	1183.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
NMLHFLOH_00749	1121115.AXVN01000022_gene1744	1.43e-51	165.0	2CAIE@1|root,33XMU@2|Bacteria,1VVJ5@1239|Firmicutes,2511G@186801|Clostridia,3Y25M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00750	457412.RSAG_02145	1.49e-274	751.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NMLHFLOH_00751	1121115.AXVN01000022_gene1742	0.0	1867.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NMLHFLOH_00752	1121115.AXVN01000022_gene1741	1.13e-225	623.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NMLHFLOH_00753	1121115.AXVN01000022_gene1740	0.0	1456.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3XYVD@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NMLHFLOH_00754	457412.RSAG_02139	4.02e-176	489.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3WKFF@541000|Ruminococcaceae	186801|Clostridia	S	Phosphoribosyl transferase domain	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NMLHFLOH_00755	1121115.AXVN01000022_gene1738	7.07e-92	269.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00756	457412.RSAG_02137	2.55e-247	681.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3WIZQ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00757	1121115.AXVN01000022_gene1736	1.14e-197	549.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3XZJU@572511|Blautia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NMLHFLOH_00758	1121115.AXVN01000022_gene1735	1.78e-301	824.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24IXJ@186801|Clostridia,3Y2B7@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NMLHFLOH_00759	1121115.AXVN01000022_gene1734	4.33e-57	177.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3Y0CN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NMLHFLOH_00760	1121115.AXVN01000022_gene1733	0.0	1649.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
NMLHFLOH_00761	1121115.AXVN01000022_gene1732	0.0	983.0	COG3757@1|root,COG5263@1|root,COG3757@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3Y010@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25
NMLHFLOH_00762	457412.RSAG_02130	1.73e-70	213.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NMLHFLOH_00763	1121115.AXVN01000022_gene1730	1.84e-76	228.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NMLHFLOH_00764	1121115.AXVN01000022_gene1729	3.35e-218	602.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3XZM2@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
NMLHFLOH_00765	1121115.AXVN01000022_gene1728	5.3e-240	658.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00766	457412.RSAG_02126	0.0	875.0	COG0027@1|root,COG0027@2|Bacteria,1UKI5@1239|Firmicutes,25FXP@186801|Clostridia,3WIMW@541000|Ruminococcaceae	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NMLHFLOH_00767	457412.RSAG_02125	2.71e-284	775.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3WI1W@541000|Ruminococcaceae	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NMLHFLOH_00768	457412.RSAG_02124	6.95e-300	819.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00769	1121115.AXVN01000022_gene1724	1.89e-138	390.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
NMLHFLOH_00770	457412.RSAG_02122	7.18e-193	535.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
NMLHFLOH_00771	1121115.AXVN01000072_gene3917	3.01e-311	847.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
NMLHFLOH_00772	457412.RSAG_02120	0.0	1456.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,3WN5Y@541000|Ruminococcaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
NMLHFLOH_00773	457412.RSAG_02119	0.0	1654.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2,Methyltransf_23
NMLHFLOH_00774	457412.RSAG_02118	0.0	1642.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NMLHFLOH_00775	457412.RSAG_02117	0.0	988.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3WK06@541000|Ruminococcaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
NMLHFLOH_00776	1121115.AXVN01000072_gene3912	5.33e-290	795.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZGM@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_00777	1121115.AXVN01000072_gene3911	0.0	1291.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYRF@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NMLHFLOH_00778	1121115.AXVN01000072_gene3910	1.85e-239	657.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
NMLHFLOH_00779	457412.RSAG_02113	0.0	909.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WRHZ@541000|Ruminococcaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
NMLHFLOH_00780	457412.RSAG_02112	5.49e-272	752.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3WGW9@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NMLHFLOH_00781	1121115.AXVN01000072_gene3907	5.28e-237	650.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3XZN2@572511|Blautia	186801|Clostridia	S	LPS side chain defect rhamnosyl transferase	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NMLHFLOH_00782	1121115.AXVN01000072_gene3906	0.0	875.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XZRU@572511|Blautia	186801|Clostridia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NMLHFLOH_00783	1121115.AXVN01000063_gene700	0.0	907.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NMLHFLOH_00784	1121115.AXVN01000063_gene701	5.57e-100	294.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24JQJ@186801|Clostridia,3Y0KF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
NMLHFLOH_00785	1121115.AXVN01000063_gene702	0.0	888.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VRK1@1239|Firmicutes,25KN7@186801|Clostridia,3Y1XU@572511|Blautia	186801|Clostridia	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00786	457412.RSAG_02106	3.1e-269	737.0	COG4733@1|root,COG4733@2|Bacteria,1VDWT@1239|Firmicutes,24ZKB@186801|Clostridia,3WMCI@541000|Ruminococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
NMLHFLOH_00788	1121115.AXVN01000063_gene704	3.2e-267	730.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NMLHFLOH_00789	457412.RSAG_02104	0.0	2089.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NMLHFLOH_00790	457412.RSAG_02103	2.16e-239	658.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NMLHFLOH_00791	457412.RSAG_02102	9.95e-216	596.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,3WHAS@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM DNA binding domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
NMLHFLOH_00792	1121115.AXVN01000063_gene708	2.67e-39	130.0	COG3585@1|root,COG3585@2|Bacteria,1VEPR@1239|Firmicutes,24QTI@186801|Clostridia	186801|Clostridia	H	pfam tobe	mopI	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
NMLHFLOH_00793	1121115.AXVN01000063_gene709	5.22e-184	515.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NMLHFLOH_00794	457412.RSAG_04589	3e-156	439.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3WIYG@541000|Ruminococcaceae	186801|Clostridia	P	Molybdate ABC transporter	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NMLHFLOH_00795	457412.RSAG_04588	7.5e-263	719.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NMLHFLOH_00796	1121115.AXVN01000063_gene712	1.44e-256	704.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,25N06@186801|Clostridia,3XYXQ@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NMLHFLOH_00797	1121115.AXVN01000063_gene713	3.33e-266	729.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NMLHFLOH_00798	457412.RSAG_02096	1.52e-239	659.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3WHSG@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NMLHFLOH_00799	457412.RSAG_02095	3.02e-44	143.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NMLHFLOH_00800	1121115.AXVN01000063_gene716	1.11e-106	307.0	2DZF8@1|root,32V97@2|Bacteria,1VK00@1239|Firmicutes,24NVD@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00801	457412.RSAG_02093	4.16e-233	640.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24BWK@186801|Clostridia,3WRSH@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NMLHFLOH_00802	457412.RSAG_02092	5.56e-246	675.0	COG1192@1|root,COG1192@2|Bacteria,1VHM0@1239|Firmicutes,24FNK@186801|Clostridia	186801|Clostridia	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NMLHFLOH_00803	457412.RSAG_03513	6.61e-57	176.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3WHSG@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NMLHFLOH_00804	457412.RSAG_04591	0.0	888.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NMLHFLOH_00805	1121115.AXVN01000079_gene2744	1.59e-241	663.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,3Y2EI@572511|Blautia	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
NMLHFLOH_00806	1121115.AXVN01000079_gene2743	5.17e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,25BAU@186801|Clostridia,3Y2E5@572511|Blautia	186801|Clostridia	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
NMLHFLOH_00807	457412.RSAG_02088	2.07e-160	448.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NMLHFLOH_00808	457412.RSAG_02087	1.77e-314	858.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3WHQP@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_00809	1121115.AXVN01000079_gene2739	5.29e-145	409.0	2C0W2@1|root,306ZY@2|Bacteria,1V5YY@1239|Firmicutes,24I0Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_7,MqsA_antitoxin
NMLHFLOH_00810	1121115.AXVN01000079_gene2738	2.62e-88	265.0	2BYUU@1|root,2Z7P3@2|Bacteria,1UYDK@1239|Firmicutes,249UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00811	483218.BACPEC_03145	5e-73	221.0	2CTWT@1|root,32SU8@2|Bacteria,1VAM2@1239|Firmicutes,24NXF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00812	1410674.JNKU01000036_gene431	7.58e-210	579.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes	1239|Firmicutes	L	Integrase core domain protein	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
NMLHFLOH_00813	457412.RSAG_02534	4.04e-154	432.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3WIMM@541000|Ruminococcaceae	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NMLHFLOH_00814	1121115.AXVN01000008_gene2663	3.01e-192	535.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3XZSJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
NMLHFLOH_00815	1121115.AXVN01000008_gene2662	2.13e-40	133.0	COG4608@1|root,COG4608@2|Bacteria,1W0U9@1239|Firmicutes,252YQ@186801|Clostridia	186801|Clostridia	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00816	457412.RSAG_02531	0.0	2197.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WHQM@541000|Ruminococcaceae	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3
NMLHFLOH_00817	457412.RSAG_02530	4.25e-250	684.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
NMLHFLOH_00818	1121115.AXVN01000008_gene2659	0.0	954.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
NMLHFLOH_00819	1121115.AXVN01000008_gene2658	8.84e-43	140.0	2DP4E@1|root,330GX@2|Bacteria,1VEZ7@1239|Firmicutes,24SE1@186801|Clostridia,3Y0WR@572511|Blautia	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NMLHFLOH_00820	457412.RSAG_02527	0.0	1000.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3WI3M@541000|Ruminococcaceae	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NMLHFLOH_00821	457412.RSAG_02526	2.02e-137	388.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,24G4C@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NMLHFLOH_00822	1121115.AXVN01000163_gene910	5.98e-55	172.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,3Y0DI@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_00823	1121115.AXVN01000163_gene909	7.78e-284	774.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,3Y049@572511|Blautia	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
NMLHFLOH_00824	457412.RSAG_02523	2.91e-109	314.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24HI8@186801|Clostridia,3WIP1@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_00825	457412.RSAG_02522	1.47e-131	374.0	COG1102@1|root,COG1102@2|Bacteria,1UXGP@1239|Firmicutes,259Y0@186801|Clostridia,3WQJG@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_00826	457412.RSAG_02521	1.77e-174	489.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia,3WNCH@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
NMLHFLOH_00827	411470.RUMGNA_02829	2.76e-171	518.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3Y0EJ@572511|Blautia	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH
NMLHFLOH_00828	411470.RUMGNA_02828	1.86e-133	394.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3Y0R0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Sortase,YibE_F
NMLHFLOH_00829	518637.EUBIFOR_00794	7.2e-149	423.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
NMLHFLOH_00830	457412.RSAG_02518	0.0	1577.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,3WH2C@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
NMLHFLOH_00831	457412.RSAG_02517	3.05e-280	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V48A@1239|Firmicutes,24GUP@186801|Clostridia,3WRJR@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_00832	1121115.AXVN01000060_gene481	0.0	1158.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KCW@186801|Clostridia,3Y11X@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NMLHFLOH_00833	457412.RSAG_02515	0.0	890.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_8,TAT_signal
NMLHFLOH_00834	457412.RSAG_02514	4.47e-198	550.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NMLHFLOH_00835	1121115.AXVN01000060_gene478	6.33e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
NMLHFLOH_00836	457412.RSAG_02512	0.0	1001.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,247VJ@186801|Clostridia,3WNXK@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,F5_F8_type_C,FIVAR,Gram_pos_anchor
NMLHFLOH_00838	1121115.AXVN01000060_gene474	1.24e-235	649.0	COG1609@1|root,COG1609@2|Bacteria,1TSU0@1239|Firmicutes,24C3S@186801|Clostridia,3XZBF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NMLHFLOH_00839	457412.RSAG_02509	4.41e-219	605.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NMLHFLOH_00840	1121115.AXVN01000060_gene471	3.2e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NMLHFLOH_00841	1121115.AXVN01000060_gene470	0.0	1139.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
NMLHFLOH_00842	457412.RSAG_02506	0.0	1023.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WHUY@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NMLHFLOH_00843	457412.RSAG_02505	7.93e-59	181.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	sacC5	-	2.7.1.4,3.2.1.80	ko:K00847,ko:K03332	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R00879,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N,PfkB
NMLHFLOH_00844	457412.RSAG_02504	0.0	1627.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,3WHDT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
NMLHFLOH_00845	1121115.AXVN01000034_gene3862	1.24e-311	851.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYNC@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00846	1121115.AXVN01000034_gene3863	1.26e-137	389.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_00847	457412.RSAG_02495	0.0	1082.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_5,Glycos_transf_1
NMLHFLOH_00848	1121115.AXVN01000034_gene3865	2.16e-156	438.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,25B9E@186801|Clostridia,3Y2DZ@572511|Blautia	186801|Clostridia	Q	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NMLHFLOH_00849	411461.DORFOR_02199	3.51e-176	492.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00850	1121115.AXVN01000034_gene3867	1.75e-186	518.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,3Y152@572511|Blautia	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
NMLHFLOH_00851	1121115.AXVN01000034_gene3868	1.7e-239	656.0	COG1073@1|root,COG1073@2|Bacteria,1TTB0@1239|Firmicutes,24ATA@186801|Clostridia,3Y186@572511|Blautia	186801|Clostridia	S	BAAT / Acyl-CoA thioester hydrolase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	BAAT_C
NMLHFLOH_00852	1256908.HMPREF0373_01304	2.8e-185	515.0	COG1073@1|root,COG1073@2|Bacteria,1TQ63@1239|Firmicutes,24A0A@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00853	1121115.AXVN01000034_gene3870	5.42e-254	696.0	COG4977@1|root,COG4977@2|Bacteria,1UK39@1239|Firmicutes,25FHZ@186801|Clostridia,3Y1JI@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NMLHFLOH_00854	1121115.AXVN01000034_gene3871	1.96e-170	476.0	COG2138@1|root,COG2138@2|Bacteria,1V7F7@1239|Firmicutes,24JKU@186801|Clostridia	186801|Clostridia	S	Cobalamin (vitamin B12) biosynthesis CbiX protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00855	1121115.AXVN01000034_gene3872	1.2e-151	426.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3XZTU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_00856	1121115.AXVN01000034_gene3873	0.0	1111.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,3XZ4W@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_00857	1121115.AXVN01000034_gene3874	0.0	1084.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3XZSV@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_00858	457412.RSAG_02489	9.28e-71	227.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00859	457412.RSAG_02488	5.08e-262	717.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_00860	457412.RSAG_02487	3.24e-40	133.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NMLHFLOH_00861	457412.RSAG_02486	4.34e-99	288.0	2DZF8@1|root,33ZUF@2|Bacteria,1VYFM@1239|Firmicutes,25E2Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00862	457412.RSAG_02485	2.75e-209	577.0	COG2267@1|root,COG2267@2|Bacteria,1TR25@1239|Firmicutes,24APA@186801|Clostridia,3WKUN@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NMLHFLOH_00864	457412.RSAG_02483	1.14e-48	155.0	2DN0F@1|root,32UQJ@2|Bacteria,1VBR6@1239|Firmicutes,24NWZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NMLHFLOH_00865	457412.RSAG_02482	1.06e-110	318.0	28IR3@1|root,2Z8QN@2|Bacteria,1UKI8@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791,DUF3990
NMLHFLOH_00866	457412.RSAG_02481	8.17e-52	163.0	2EC32@1|root,33621@2|Bacteria,1VIVU@1239|Firmicutes,24Q0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
NMLHFLOH_00867	457412.RSAG_00820	1.07e-26	103.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NMLHFLOH_00868	457412.RSAG_02479	0.0	1644.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NMLHFLOH_00869	1121115.AXVN01000101_gene821	1.44e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NMLHFLOH_00870	457412.RSAG_02477	0.0	1013.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
NMLHFLOH_00871	457412.RSAG_02476	1.25e-240	661.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_00872	457412.RSAG_02475	0.0	884.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NMLHFLOH_00873	1121115.AXVN01000101_gene817	5.25e-208	575.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3Y0AZ@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_00874	457412.RSAG_02473	2.61e-102	296.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3WRVD@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NMLHFLOH_00875	1121115.AXVN01000101_gene815	0.0	1321.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_00876	1121115.AXVN01000101_gene814	0.0	1169.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZ2D@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_00877	457412.RSAG_02470	0.0	1333.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,3WHDZ@541000|Ruminococcaceae	186801|Clostridia	L	Superfamily I DNA and RNA	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
NMLHFLOH_00878	1121115.AXVN01000051_gene793	3.69e-195	549.0	2EWK9@1|root,33PYD@2|Bacteria,1VTXK@1239|Firmicutes,24ZC9@186801|Clostridia,3Y0MZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00879	457412.RSAG_02468	1.52e-198	549.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3WSIZ@541000|Ruminococcaceae	186801|Clostridia	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NMLHFLOH_00880	1121115.AXVN01000051_gene795	1.35e-203	564.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NMLHFLOH_00881	457412.RSAG_02465	0.0	1291.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3WH2R@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NMLHFLOH_00882	457412.RSAG_02464	1.48e-89	263.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3WK5R@541000|Ruminococcaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00883	1121115.AXVN01000051_gene798	0.0	2192.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
NMLHFLOH_00884	1121115.AXVN01000051_gene799	0.0	2400.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NMLHFLOH_00885	457412.RSAG_02461	0.0	943.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NMLHFLOH_00886	1121115.AXVN01000051_gene801	2.25e-70	212.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NMLHFLOH_00887	457412.RSAG_02459	1.22e-118	344.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NMLHFLOH_00888	1121115.AXVN01000051_gene803	4.03e-140	405.0	2DN7I@1|root,32VZ1@2|Bacteria,1UJVJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NMLHFLOH_00889	1121115.AXVN01000051_gene804	6.14e-39	129.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,3Y0IZ@572511|Blautia	186801|Clostridia	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
NMLHFLOH_00890	1121115.AXVN01000051_gene805	9.68e-36	121.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
NMLHFLOH_00891	457412.RSAG_02455	4.82e-228	628.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3WI38@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NMLHFLOH_00892	457412.RSAG_02454	7.07e-97	282.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
NMLHFLOH_00893	1121115.AXVN01000057_gene2514	6.65e-217	606.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NMLHFLOH_00894	457412.RSAG_02452	0.0	1142.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00895	1121115.AXVN01000051_gene807	1.92e-37	140.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4384,TonB_dep_Rec
NMLHFLOH_00896	457412.RSAG_02450	0.0	1098.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	4.2.2.5	ko:K19049	-	-	-	-	ko00000,ko01000	-	PL8	-	Beta_helix,Big_2,Big_5,LRR_5,Lyase_8,SLH,VWA
NMLHFLOH_00897	457412.RSAG_02449	1.47e-60	188.0	COG3385@1|root,COG3385@2|Bacteria,1VPWS@1239|Firmicutes,24V8I@186801|Clostridia	186801|Clostridia	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00898	457412.RSAG_02448	0.0	1058.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NMLHFLOH_00899	457412.RSAG_02723	2.62e-158	443.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3WGWR@541000|Ruminococcaceae	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NMLHFLOH_00900	1121115.AXVN01000054_gene1871	6.37e-299	814.0	29WP9@1|root,30IA6@2|Bacteria,1V4GZ@1239|Firmicutes,24HWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00901	457412.RSAG_02721	0.0	1496.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NMLHFLOH_00902	1121115.AXVN01000054_gene1873	1.21e-212	587.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_00903	457412.RSAG_02719	4.24e-183	511.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_00904	457412.RSAG_02718	6.43e-211	584.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00905	457412.RSAG_02717	1.62e-169	473.0	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,24PSE@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_00906	457412.RSAG_02716	0.0	1063.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_00907	1121115.AXVN01000054_gene1879	3.75e-63	193.0	COG2026@1|root,COG2026@2|Bacteria,1V7AZ@1239|Firmicutes,24KDM@186801|Clostridia	186801|Clostridia	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE-like_toxin
NMLHFLOH_00908	1121115.AXVN01000054_gene1880	1.19e-80	239.0	COG2002@1|root,COG2002@2|Bacteria,1V8G8@1239|Firmicutes,24JVE@186801|Clostridia	186801|Clostridia	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00909	1121115.AXVN01000054_gene1881	1.34e-232	640.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,3Y13M@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
NMLHFLOH_00910	457412.RSAG_02712	2.69e-186	518.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3WKDD@541000|Ruminococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
NMLHFLOH_00911	457412.RSAG_02711	4.06e-134	380.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WK2K@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NMLHFLOH_00912	457412.RSAG_02710	1.59e-308	839.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
NMLHFLOH_00913	457412.RSAG_02709	5.72e-113	323.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3WJE3@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NMLHFLOH_00914	457412.RSAG_02708	6.08e-106	305.0	2DV0M@1|root,32UY9@2|Bacteria,1VC55@1239|Firmicutes,24TS3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00915	457412.RSAG_02707	5.25e-106	306.0	2BZUE@1|root,31TAF@2|Bacteria,1URY6@1239|Firmicutes,24XVK@186801|Clostridia,3WQSR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00916	457412.RSAG_02706	6.5e-73	219.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
NMLHFLOH_00917	457412.RSAG_02705	8.21e-133	380.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
NMLHFLOH_00918	1121115.AXVN01000054_gene1891	5.88e-31	110.0	2C1K5@1|root,3415T@2|Bacteria,1VY97@1239|Firmicutes,2522U@186801|Clostridia,3Y25V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00919	457412.RSAG_02702	1.68e-228	629.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NMLHFLOH_00920	1121115.AXVN01000054_gene1893	5.43e-165	463.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3Y1P9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00921	457412.RSAG_02700	2.18e-107	310.0	2BWHH@1|root,33G8D@2|Bacteria,1VM1X@1239|Firmicutes,24W5T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00922	1121115.AXVN01000054_gene1895	3.36e-117	335.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3Y1N5@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_00923	457412.RSAG_02698	1.02e-278	761.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NMLHFLOH_00924	457412.RSAG_02697	6.76e-213	587.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NMLHFLOH_00925	1121115.AXVN01000054_gene1898	8.22e-269	737.0	COG3103@1|root,COG3103@2|Bacteria,1UG5Z@1239|Firmicutes,25NDX@186801|Clostridia,3Y048@572511|Blautia	186801|Clostridia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00926	457412.RSAG_02693	7.92e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UJ12@1239|Firmicutes,24Q7D@186801|Clostridia,3WKDP@541000|Ruminococcaceae	186801|Clostridia	T	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
NMLHFLOH_00927	457412.RSAG_02692	5.51e-195	539.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,24IZQ@186801|Clostridia,3WNI3@541000|Ruminococcaceae	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_00928	1121115.AXVN01000124_gene3954	6.35e-163	456.0	COG2755@1|root,COG2755@2|Bacteria,1VT0W@1239|Firmicutes,25BMQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NMLHFLOH_00929	1121115.AXVN01000124_gene3953	1.97e-151	426.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NMLHFLOH_00930	1121115.AXVN01000124_gene3952	3.21e-32	113.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NMLHFLOH_00931	457412.RSAG_02688	1.16e-87	260.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NMLHFLOH_00932	1121115.AXVN01000124_gene3950	3.6e-112	322.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3Y09Z@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NMLHFLOH_00933	457412.RSAG_02686	0.0	957.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NMLHFLOH_00934	457412.RSAG_02685	1.64e-206	572.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NMLHFLOH_00935	1121115.AXVN01000124_gene3947	0.0	911.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NMLHFLOH_00936	1121115.AXVN01000124_gene3946	6.42e-87	256.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NMLHFLOH_00937	457412.RSAG_02682	0.0	971.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NMLHFLOH_00938	457412.RSAG_02681	1.9e-231	637.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3WGEJ@541000|Ruminococcaceae	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
NMLHFLOH_00939	457412.RSAG_02679	0.0	1607.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
NMLHFLOH_00940	457412.RSAG_02678	1.17e-124	355.0	COG1989@1|root,COG1989@2|Bacteria,1VF54@1239|Firmicutes,24RX8@186801|Clostridia,3WKQB@541000|Ruminococcaceae	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
NMLHFLOH_00941	1121115.AXVN01000023_gene1770	7.93e-248	680.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia,3XZ68@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NMLHFLOH_00942	1121115.AXVN01000023_gene1771	1.33e-276	757.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NMLHFLOH_00943	457412.RSAG_02675	5.83e-176	491.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3WJUZ@541000|Ruminococcaceae	186801|Clostridia	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NMLHFLOH_00944	457412.RSAG_02674	6.38e-235	647.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3WJSN@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NMLHFLOH_00945	1121115.AXVN01000023_gene1774	1.49e-32	113.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
NMLHFLOH_00946	1121115.AXVN01000023_gene1775	0.0	933.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,3XZFX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00947	1121115.AXVN01000023_gene1776	5.5e-201	556.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3Y0C5@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NMLHFLOH_00948	1121115.AXVN01000023_gene1777	2.57e-97	283.0	COG1989@1|root,COG1989@2|Bacteria,1VMFT@1239|Firmicutes	1239|Firmicutes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
NMLHFLOH_00949	1121115.AXVN01000023_gene1778	1.77e-103	299.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NMLHFLOH_00950	457412.RSAG_02668	0.0	955.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3WRV5@541000|Ruminococcaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NMLHFLOH_00951	457412.RSAG_02667	3.08e-134	380.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3WJRW@541000|Ruminococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
NMLHFLOH_00952	1121115.AXVN01000023_gene1781	1.83e-164	459.0	COG3852@1|root,COG3852@2|Bacteria,1VA7P@1239|Firmicutes,24J8F@186801|Clostridia,3Y29E@572511|Blautia	186801|Clostridia	H	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NMLHFLOH_00953	1121115.AXVN01000023_gene1782	5.29e-95	276.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3Y034@572511|Blautia	186801|Clostridia	FG	Psort location Cytoplasmic, score 8.87	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NMLHFLOH_00954	1121115.AXVN01000023_gene1783	1.15e-122	350.0	2DUBI@1|root,33PTJ@2|Bacteria,1VRWC@1239|Firmicutes,24Y88@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
NMLHFLOH_00955	1121115.AXVN01000023_gene1784	5.23e-256	702.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NMLHFLOH_00956	1121115.AXVN01000023_gene1785	9.21e-89	261.0	2EXFY@1|root,33QS9@2|Bacteria,1VU5K@1239|Firmicutes,24YDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00957	1121115.AXVN01000023_gene1786	0.0	1099.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
NMLHFLOH_00958	1121115.AXVN01000023_gene1787	9.1e-54	168.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NMLHFLOH_00959	1121115.AXVN01000023_gene1788	7.42e-162	453.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NMLHFLOH_00960	1121115.AXVN01000023_gene1789	5.84e-86	253.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00961	457412.RSAG_02657	1.45e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3WSRX@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
NMLHFLOH_00962	1121115.AXVN01000023_gene1791	0.0	1579.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3XYUK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NMLHFLOH_00963	1121115.AXVN01000023_gene1792	0.0	993.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NMLHFLOH_00964	457412.RSAG_02654	0.0	1501.0	COG2247@1|root,COG2755@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,1UKIA@1239|Firmicutes,25FXT@186801|Clostridia,3WMKI@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00965	1121115.AXVN01000023_gene1794	0.0	940.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NMLHFLOH_00966	1121115.AXVN01000023_gene1795	1.06e-261	716.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
NMLHFLOH_00967	1121115.AXVN01000023_gene1796	4.86e-298	816.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3XZEZ@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
NMLHFLOH_00968	1121115.AXVN01000023_gene1797	1.17e-290	793.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3XYUR@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
NMLHFLOH_00969	457412.RSAG_02649	5.45e-232	639.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NMLHFLOH_00970	457412.RSAG_02648	3.54e-267	733.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
NMLHFLOH_00971	457412.RSAG_02647	0.0	922.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NMLHFLOH_00972	1121115.AXVN01000023_gene1801	5.33e-304	829.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NMLHFLOH_00973	1121115.AXVN01000023_gene1802	6.35e-256	703.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NMLHFLOH_00974	1121115.AXVN01000023_gene1803	3.27e-58	180.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
NMLHFLOH_00975	1121115.AXVN01000023_gene1804	1.22e-187	536.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
NMLHFLOH_00976	1121115.AXVN01000023_gene1805	6.92e-171	476.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NMLHFLOH_00977	1121115.AXVN01000023_gene1806	2.48e-254	697.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00979	457412.RSAG_02640	3.1e-112	322.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3WJHQ@541000|Ruminococcaceae	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NMLHFLOH_00980	457412.RSAG_02639	0.0	895.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_00981	1121115.AXVN01000023_gene1809	1.1e-258	709.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NMLHFLOH_00982	457412.RSAG_02637	0.0	1045.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NMLHFLOH_00983	1121115.AXVN01000122_gene2850	3.98e-72	217.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NMLHFLOH_00984	1121115.AXVN01000122_gene2851	2.17e-140	396.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
NMLHFLOH_00985	457412.RSAG_02634	1.1e-258	709.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3WIXJ@541000|Ruminococcaceae	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NMLHFLOH_00986	1121115.AXVN01000122_gene2853	1.24e-148	419.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NMLHFLOH_00987	1121115.AXVN01000122_gene2854	9.51e-202	558.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NMLHFLOH_00988	1121115.AXVN01000122_gene2855	1.38e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NMLHFLOH_00989	1121115.AXVN01000122_gene2856	4.45e-128	364.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3Y027@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
NMLHFLOH_00990	1121115.AXVN01000122_gene2857	9.37e-284	780.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NMLHFLOH_00991	1121115.AXVN01000122_gene2858	6.56e-280	768.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_00992	457412.RSAG_02627	4.61e-156	439.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,257PM@186801|Clostridia,3WK8E@541000|Ruminococcaceae	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
NMLHFLOH_00993	457412.RSAG_00602	0.0	966.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,3WJ03@541000|Ruminococcaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NMLHFLOH_00994	457412.RSAG_00603	2.27e-130	376.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia,3WH98@541000|Ruminococcaceae	186801|Clostridia	KT	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
NMLHFLOH_00995	1121115.AXVN01000003_gene1585	2.09e-136	386.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NMLHFLOH_00996	1121115.AXVN01000003_gene1586	7.09e-180	501.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
NMLHFLOH_00997	457412.RSAG_00606	2.29e-227	627.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
NMLHFLOH_00998	457412.RSAG_00607	8.1e-200	553.0	COG4733@1|root,COG4733@2|Bacteria,1UICW@1239|Firmicutes,25EHW@186801|Clostridia	186801|Clostridia	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
NMLHFLOH_00999	1121115.AXVN01000003_gene1589	2.32e-200	555.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NMLHFLOH_01000	457412.RSAG_00609	1.56e-138	392.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
NMLHFLOH_01001	457412.RSAG_00610	3.57e-164	458.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3WP7T@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NMLHFLOH_01002	457412.RSAG_00611	0.0	1287.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3WI2J@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NMLHFLOH_01003	457412.RSAG_00612	2.8e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3WNXA@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NMLHFLOH_01004	1121115.AXVN01000003_gene1594	0.0	881.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
NMLHFLOH_01005	457412.RSAG_00614	6.72e-215	594.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3WNH3@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
NMLHFLOH_01006	457412.RSAG_00615	0.0	1407.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
NMLHFLOH_01007	457412.RSAG_00616	4.82e-178	496.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3WNTV@541000|Ruminococcaceae	186801|Clostridia	D	Anion-transporting ATPase	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NMLHFLOH_01008	1121115.AXVN01000003_gene1599	0.0	1263.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NMLHFLOH_01009	1121115.AXVN01000003_gene1600	1.83e-183	510.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NMLHFLOH_01010	1121115.AXVN01000003_gene1601	1.02e-34	118.0	2FK7C@1|root,34BV3@2|Bacteria,1W6KA@1239|Firmicutes,254TZ@186801|Clostridia,3Y0MF@572511|Blautia	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
NMLHFLOH_01011	457412.RSAG_00620	1.16e-68	209.0	2CEVS@1|root,30HAB@2|Bacteria,1UHCU@1239|Firmicutes,25Q3B@186801|Clostridia,3WR1K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01012	457412.RSAG_00621	1.03e-203	563.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3WHB2@541000|Ruminococcaceae	186801|Clostridia	S	Aldo keto reductases, related to diketogulonate reductase	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NMLHFLOH_01013	457412.RSAG_00622	3.31e-239	658.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NMLHFLOH_01014	457412.RSAG_00623	9.81e-149	419.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3WJ4W@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NMLHFLOH_01015	457412.RSAG_00624	2.91e-312	851.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NMLHFLOH_01016	1121115.AXVN01000003_gene1607	0.0	917.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3XYRJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NMLHFLOH_01017	457412.RSAG_00626	2.16e-283	774.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NMLHFLOH_01018	1121115.AXVN01000003_gene1609	1.12e-211	583.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NMLHFLOH_01019	457412.RSAG_00628	1.6e-86	254.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3WMJ4@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NMLHFLOH_01020	1121115.AXVN01000003_gene1611	3.38e-172	481.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NMLHFLOH_01021	1121115.AXVN01000003_gene1612	1.46e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
NMLHFLOH_01022	457412.RSAG_00631	4.9e-138	390.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3WRVN@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NMLHFLOH_01023	1121115.AXVN01000003_gene1614	1.64e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NMLHFLOH_01024	1121115.AXVN01000003_gene1615	5.65e-220	606.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
NMLHFLOH_01025	1121115.AXVN01000003_gene1616	1.32e-187	525.0	COG2885@1|root,COG2885@2|Bacteria,1V6HB@1239|Firmicutes,24ARV@186801|Clostridia,3Y17K@572511|Blautia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
NMLHFLOH_01026	1121115.AXVN01000003_gene1617	0.0	1017.0	COG0497@1|root,COG0497@2|Bacteria,1UJV8@1239|Firmicutes,25FAU@186801|Clostridia	186801|Clostridia	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
NMLHFLOH_01027	1121115.AXVN01000003_gene1618	2.26e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,3Y2AD@572511|Blautia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NMLHFLOH_01028	457412.RSAG_00637	0.0	1565.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NMLHFLOH_01029	457412.RSAG_00638	5.78e-225	622.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NMLHFLOH_01030	1121115.AXVN01000003_gene1622	0.0	899.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
NMLHFLOH_01031	1121115.AXVN01000003_gene1623	9.66e-219	602.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NMLHFLOH_01032	1121115.AXVN01000003_gene1624	5.56e-166	465.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3XZDI@572511|Blautia	186801|Clostridia	OU	Psort location Cytoplasmic, score 8.87	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NMLHFLOH_01033	1121115.AXVN01000003_gene1625	1.38e-167	469.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NMLHFLOH_01034	1121115.AXVN01000003_gene1626	2.38e-309	843.0	COG1253@1|root,COG1253@2|Bacteria,1U77R@1239|Firmicutes,25CBE@186801|Clostridia,3XZ2E@572511|Blautia	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NMLHFLOH_01035	457412.RSAG_00644	1.2e-76	228.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NMLHFLOH_01036	1121115.AXVN01000003_gene1628	1.68e-276	756.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NMLHFLOH_01037	1121115.AXVN01000003_gene1629	0.0	981.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3XZEG@572511|Blautia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NMLHFLOH_01038	457412.RSAG_00647	1.83e-149	421.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3WHYJ@541000|Ruminococcaceae	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NMLHFLOH_01039	1121115.AXVN01000003_gene1631	0.0	1171.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NMLHFLOH_01040	1121115.AXVN01000003_gene1632	6.59e-296	806.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NMLHFLOH_01041	1121115.AXVN01000003_gene1633	2.43e-205	567.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3XYHC@572511|Blautia	186801|Clostridia	O	Psort location Extracellular, score	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
NMLHFLOH_01042	1121115.AXVN01000003_gene1635	1.14e-175	489.0	COG0500@1|root,COG0500@2|Bacteria,1UKI1@1239|Firmicutes,25FXJ@186801|Clostridia	186801|Clostridia	Q	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
NMLHFLOH_01043	1121115.AXVN01000003_gene1636	0.0	1000.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
NMLHFLOH_01044	1121115.AXVN01000003_gene1638	4.76e-159	445.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
NMLHFLOH_01046	457412.RSAG_04751	4.56e-255	699.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,3WRJU@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_01047	1256908.HMPREF0373_00285	1.17e-251	706.0	COG1672@1|root,COG1672@2|Bacteria,1TPQR@1239|Firmicutes,24AIK@186801|Clostridia,25YER@186806|Eubacteriaceae	186801|Clostridia	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_35,PDDEXK_3
NMLHFLOH_01048	457412.RSAG_00674	5.8e-242	665.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia,3WPQY@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
NMLHFLOH_01049	457412.RSAG_00675	0.0	872.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NMLHFLOH_01050	411459.RUMOBE_00755	1.21e-95	285.0	COG1309@1|root,COG1309@2|Bacteria,1TYNZ@1239|Firmicutes,24IV3@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_01051	742765.HMPREF9457_02207	2.88e-274	763.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,27W7Y@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01053	1121115.AXVN01000043_gene3384	3.06e-267	739.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01054	1121115.AXVN01000043_gene3382	1.45e-84	249.0	COG2461@1|root,COG2461@2|Bacteria,1V9ZF@1239|Firmicutes,24F8Y@186801|Clostridia	186801|Clostridia	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01055	1243664.CAVL020000039_gene618	3.85e-28	116.0	2FDGH@1|root,345I3@2|Bacteria,1VZV3@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01056	1280698.AUJS01000086_gene943	1.88e-183	516.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01057	658655.HMPREF0988_01124	6.74e-86	254.0	2BFEN@1|root,32988@2|Bacteria,1V24H@1239|Firmicutes,24GVS@186801|Clostridia,27TR5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NMLHFLOH_01059	585394.RHOM_04385	1.07e-90	267.0	2AYH2@1|root,31QKF@2|Bacteria,1V93C@1239|Firmicutes,24GEA@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NMLHFLOH_01060	1423321.AS29_00720	1.11e-232	669.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1TUJU@1239|Firmicutes,4IF20@91061|Bacilli,1ZPEI@1386|Bacillus	91061|Bacilli	S	conserved protein (DUF2081)	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01061	1121115.AXVN01000043_gene3381	3.59e-108	312.0	2E53T@1|root,32ZWT@2|Bacteria,1VJS8@1239|Firmicutes,24S8H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01062	1121115.AXVN01000043_gene3384	9.71e-154	444.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01063	887325.HMPREF0381_0056	2.2e-28	105.0	2DQV8@1|root,338W7@2|Bacteria,1VJXI@1239|Firmicutes,25DTD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NMLHFLOH_01064	596323.HMPREF0554_0754	2.06e-30	108.0	2E3EN@1|root,32YDN@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
NMLHFLOH_01070	1235802.C823_02104	9.7e-166	489.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25UXT@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01071	1235802.C823_02103	1.12e-162	475.0	COG0641@1|root,COG0641@2|Bacteria,1V5NX@1239|Firmicutes,24GI8@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NMLHFLOH_01072	1235802.C823_02101	1.05e-90	275.0	COG3279@1|root,COG3279@2|Bacteria,1V1GQ@1239|Firmicutes,24H3F@186801|Clostridia,25YUG@186806|Eubacteriaceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NMLHFLOH_01073	1235802.C823_02102	6.35e-87	278.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia,25YP8@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_01075	1121115.AXVN01000043_gene3384	8.05e-26	105.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01076	1121115.AXVN01000043_gene3383	7.95e-163	459.0	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
NMLHFLOH_01077	1094508.Tsac_2454	8.4e-174	518.0	COG0323@1|root,COG0323@2|Bacteria,1VSSE@1239|Firmicutes,24ZJR@186801|Clostridia	186801|Clostridia	L	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_3
NMLHFLOH_01078	936574.HMPREF1508_0649	3e-151	444.0	COG0210@1|root,COG0210@2|Bacteria,1W75Q@1239|Firmicutes,24SIM@186801|Clostridia	186801|Clostridia	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase
NMLHFLOH_01079	1121115.AXVN01000155_gene552	1.03e-175	492.0	COG4377@1|root,COG4377@2|Bacteria,1V3UF@1239|Firmicutes,24JI9@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2324
NMLHFLOH_01080	457412.RSAG_01589	2.33e-58	181.0	2C1NT@1|root,32JUU@2|Bacteria,1V7IC@1239|Firmicutes,24JFE@186801|Clostridia,3WPC1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01081	411463.EUBVEN_01785	1.91e-38	128.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,25XDD@186806|Eubacteriaceae	186801|Clostridia	K	adenine-specific DNA methyltransferase K06223	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NMLHFLOH_01082	471875.RUMLAC_00937	5.24e-66	201.0	292IX@1|root,2ZQ2Y@2|Bacteria,1TV0U@1239|Firmicutes,258A6@186801|Clostridia,3WMAJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01084	457412.RSAG_01585	8.49e-210	580.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3WJ1R@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NMLHFLOH_01085	457412.RSAG_01583	5.03e-67	203.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NMLHFLOH_01086	1280698.AUJS01000017_gene1830	0.0	1109.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,27UU4@189330|Dorea	186801|Clostridia	C	Rhodanese Homology Domain	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NMLHFLOH_01087	411469.EUBHAL_00731	5.45e-153	430.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,25WMM@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
NMLHFLOH_01088	457412.RSAG_01580	6.61e-182	506.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3WHEN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function  DUF134	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
NMLHFLOH_01089	457412.RSAG_01579	4.72e-72	216.0	COG2865@1|root,COG2865@2|Bacteria,1VWB8@1239|Firmicutes,2513F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01090	457412.RSAG_01578	1.33e-73	220.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K10001	ko02010,ko02020,map02010,map02020	M00230	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.19,3.A.1.3.4	-	-	GGDEF,SBP_bac_3
NMLHFLOH_01091	1121115.AXVN01000048_gene1275	2.42e-60	205.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
NMLHFLOH_01092	1121115.AXVN01000048_gene1276	1.32e-61	188.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24KYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01093	1121115.AXVN01000048_gene1277	2.41e-205	569.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NMLHFLOH_01094	457412.RSAG_01574	5.21e-195	542.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3WHZF@541000|Ruminococcaceae	186801|Clostridia	C	PFAM nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
NMLHFLOH_01095	1121115.AXVN01000048_gene1279	1.23e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3Y205@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
NMLHFLOH_01096	457412.RSAG_01572	1.72e-69	209.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NMLHFLOH_01097	457412.RSAG_01571	3.42e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NMLHFLOH_01098	1121115.AXVN01000048_gene1282	5.7e-198	548.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3Y0YS@572511|Blautia	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
NMLHFLOH_01099	457412.RSAG_01569	1.68e-103	298.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
NMLHFLOH_01101	457412.RSAG_01568	0.0	1142.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WH9N@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,Response_reg,SBP_bac_3
NMLHFLOH_01102	457412.RSAG_01567	0.0	1030.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NMLHFLOH_01103	457412.RSAG_01566	6.5e-124	352.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,3WIG7@541000|Ruminococcaceae	186801|Clostridia	I	Belongs to the Nudix hydrolase family	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NMLHFLOH_01104	457412.RSAG_01565	4.05e-141	398.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3WH3X@541000|Ruminococcaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
NMLHFLOH_01105	457412.RSAG_01564	1.33e-128	365.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,3WSDX@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NMLHFLOH_01106	457412.RSAG_01563	0.0	1081.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3WGE4@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01107	457412.RSAG_01562	0.0	1156.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WHGV@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01108	457412.RSAG_01561	2.46e-248	681.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3WG9A@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NMLHFLOH_01109	457412.RSAG_01560	0.0	2157.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
NMLHFLOH_01110	457412.RSAG_01559	7.62e-120	343.0	COG3090@1|root,COG3090@2|Bacteria,1VD6X@1239|Firmicutes,24QCX@186801|Clostridia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NMLHFLOH_01111	1121115.AXVN01000108_gene621	2.03e-100	291.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NMLHFLOH_01112	457412.RSAG_01557	0.0	1160.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24I15@186801|Clostridia,3WP5T@541000|Ruminococcaceae	186801|Clostridia	T	Cache domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NMLHFLOH_01113	1121115.AXVN01000108_gene623	0.0	1067.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia,3Y2A1@572511|Blautia	186801|Clostridia	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NMLHFLOH_01114	1121115.AXVN01000108_gene624	0.0	876.0	COG1653@1|root,COG1653@2|Bacteria,1UUUK@1239|Firmicutes,25MFP@186801|Clostridia,3Y1WB@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NMLHFLOH_01115	1121115.AXVN01000108_gene625	5.48e-204	565.0	COG1175@1|root,COG1175@2|Bacteria,1UXJE@1239|Firmicutes,25MIM@186801|Clostridia,3Y1QD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_01116	1121115.AXVN01000108_gene626	1.33e-192	535.0	COG0395@1|root,COG0395@2|Bacteria,1UXJD@1239|Firmicutes,25M52@186801|Clostridia,3Y1KD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_01117	457412.RSAG_01552	0.0	984.0	COG1621@1|root,COG1621@2|Bacteria,1U0EK@1239|Firmicutes,24AM9@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 32 N-terminal domain	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	DUF4975,Glyco_hydro_32N
NMLHFLOH_01118	457412.RSAG_01551	4.98e-273	749.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,3WISY@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NMLHFLOH_01119	457412.RSAG_01549	8.73e-87	255.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,3WM8E@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
NMLHFLOH_01120	457412.RSAG_01548	3.87e-262	719.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
NMLHFLOH_01121	457412.RSAG_01547	1.08e-218	603.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3WGJW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_01122	457412.RSAG_01546	6.32e-169	472.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NMLHFLOH_01123	457412.RSAG_01545	0.0	1166.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NMLHFLOH_01124	457412.RSAG_01544	4.93e-270	737.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NMLHFLOH_01125	457412.RSAG_01543	2.71e-150	422.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3WHMB@541000|Ruminococcaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
NMLHFLOH_01126	457412.RSAG_01542	0.0	1143.0	COG2972@1|root,COG2972@2|Bacteria,1TW41@1239|Firmicutes,24AHF@186801|Clostridia,3WJ2Z@541000|Ruminococcaceae	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NMLHFLOH_01127	457412.RSAG_01541	7.7e-168	469.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,3WJP7@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_01128	457412.RSAG_01540	4.31e-298	812.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3WH7S@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NMLHFLOH_01129	457412.RSAG_01539	3.7e-204	566.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WN1Y@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_01130	457412.RSAG_01538	1.44e-191	532.0	COG0395@1|root,COG0395@2|Bacteria,1UN1I@1239|Firmicutes,249S1@186801|Clostridia,3WI7U@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_01131	457412.RSAG_01537	0.0	1403.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3WRXQ@541000|Ruminococcaceae	186801|Clostridia	G	family 31 of glycosyl	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
NMLHFLOH_01132	457412.RSAG_01536	7.6e-307	836.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,249SA@186801|Clostridia,3WP6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NMLHFLOH_01133	457412.RSAG_01535	0.0	1427.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NMLHFLOH_01134	457412.RSAG_01534	0.0	870.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3WJP9@541000|Ruminococcaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_01135	457412.RSAG_01533	3.45e-206	570.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_01136	457412.RSAG_01532	7.99e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WIS9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_01137	457412.RSAG_01531	5.24e-193	536.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V27N@1239|Firmicutes,24EUU@186801|Clostridia,3WPI2@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_01138	457412.RSAG_01530	0.0	1152.0	COG2972@1|root,COG2972@2|Bacteria,1V4G9@1239|Firmicutes,24IA9@186801|Clostridia,3WP6J@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NMLHFLOH_01139	457412.RSAG_01529	0.0	1442.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NMLHFLOH_01140	457412.RSAG_01528	8.95e-221	608.0	COG2207@1|root,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,3WJXM@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NMLHFLOH_01141	457412.RSAG_01527	5.25e-298	813.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NMLHFLOH_01142	457412.RSAG_01526	0.0	1154.0	COG2972@1|root,COG2972@2|Bacteria,1UQDY@1239|Firmicutes,249HG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NMLHFLOH_01143	457412.RSAG_01525	0.0	1043.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NMLHFLOH_01144	457412.RSAG_01524	5.58e-270	739.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	GntR,Peripla_BP_3,Peripla_BP_4
NMLHFLOH_01145	457412.RSAG_01523	1.11e-212	588.0	COG1172@1|root,COG1172@2|Bacteria,1UVPQ@1239|Firmicutes,25MGQ@186801|Clostridia,3WPXD@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
NMLHFLOH_01146	457412.RSAG_01522	0.0	974.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WGJM@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NMLHFLOH_01147	457412.RSAG_01521	7.78e-212	587.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24B5S@186801|Clostridia,3WPSA@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NMLHFLOH_01148	457412.RSAG_01520	2.07e-201	557.0	COG5464@1|root,COG5464@2|Bacteria,1TYDT@1239|Firmicutes,24EGK@186801|Clostridia,3WKU9@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,HTH_7,PDDEXK_2
NMLHFLOH_01149	1121115.AXVN01000123_gene2860	4.28e-164	459.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,3XZIA@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_01150	1121115.AXVN01000104_gene854	9.66e-110	316.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NMLHFLOH_01151	411483.FAEPRAA2165_00092	2e-272	750.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24D0V@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NMLHFLOH_01152	411483.FAEPRAA2165_00091	6.83e-50	158.0	2C79Z@1|root,32USV@2|Bacteria,1VBYW@1239|Firmicutes,24P5N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01153	272563.CD630_10921	1.27e-46	150.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia	186801|Clostridia	S	COG NOG21981 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NMLHFLOH_01154	97139.C824_03283	2.26e-89	263.0	COG1595@1|root,COG1595@2|Bacteria,1TSH2@1239|Firmicutes,24B5P@186801|Clostridia,36RPD@31979|Clostridiaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NMLHFLOH_01155	1235792.C808_01386	2.25e-50	163.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,27PJ6@186928|unclassified Lachnospiraceae	186801|Clostridia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
NMLHFLOH_01156	1235792.C808_01385	2.98e-209	582.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,27J6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
NMLHFLOH_01157	1235792.C808_01384	2.87e-46	150.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,27NGT@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
NMLHFLOH_01158	478749.BRYFOR_08924	5.25e-72	217.0	COG1396@1|root,COG1396@2|Bacteria,1V58U@1239|Firmicutes,24HKI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_01159	457412.RSAG_01320	0.0	946.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,3WGK6@541000|Ruminococcaceae	186801|Clostridia	L	DNA-damage repair protein (DNA polymerase IV) K00961	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NMLHFLOH_01160	457412.RSAG_01319	3.06e-94	275.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,3WJTA@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01161	457412.RSAG_01318	1.03e-106	307.0	2BFEN@1|root,32988@2|Bacteria,1V9U5@1239|Firmicutes,24JWC@186801|Clostridia,3WJIN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
NMLHFLOH_01162	457412.RSAG_01317	1.07e-238	655.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia,3WHKG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01163	457412.RSAG_01316	5e-130	369.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3WIA5@541000|Ruminococcaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
NMLHFLOH_01164	457412.RSAG_01315	1.48e-119	341.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3WJVP@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NMLHFLOH_01165	457412.RSAG_01314	3.18e-195	541.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WHB5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
NMLHFLOH_01166	457412.RSAG_01313	1.16e-204	566.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3WI4F@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
NMLHFLOH_01167	1121115.AXVN01000114_gene1675	1.45e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,3Y09F@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NMLHFLOH_01168	457412.RSAG_01311	6.04e-309	841.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3WH7R@541000|Ruminococcaceae	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NMLHFLOH_01169	457412.RSAG_01310	1.25e-201	557.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia,3WKHA@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NMLHFLOH_01170	457412.RSAG_01309	7.01e-217	599.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WI18@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NMLHFLOH_01171	457412.RSAG_04656	4.65e-256	701.0	COG2365@1|root,COG2365@2|Bacteria,1V639@1239|Firmicutes,25CGQ@186801|Clostridia	186801|Clostridia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
NMLHFLOH_01172	1121115.AXVN01000170_gene503	5.14e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NMLHFLOH_01173	1121115.AXVN01000170_gene502	9.63e-248	679.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NMLHFLOH_01174	457412.RSAG_01304	1.99e-122	349.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01175	1121115.AXVN01000001_gene1176	5.14e-42	137.0	2FI33@1|root,349VV@2|Bacteria,1VYV4@1239|Firmicutes,253ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01176	457412.RSAG_01302	5.89e-171	477.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_01177	457412.RSAG_01301	2.07e-300	820.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_01178	457412.RSAG_01300	1.07e-150	423.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3WM7H@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NMLHFLOH_01179	1121115.AXVN01000001_gene1172	0.0	909.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
NMLHFLOH_01180	457412.RSAG_01298	4.71e-142	401.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3WJCH@541000|Ruminococcaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NMLHFLOH_01181	457412.RSAG_01297	6.32e-274	751.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NMLHFLOH_01182	457412.RSAG_01296	9.18e-242	664.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NMLHFLOH_01183	457412.RSAG_01295	6.24e-83	249.0	COG3103@1|root,COG3103@2|Bacteria,1VQZ3@1239|Firmicutes,24XYH@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NMLHFLOH_01184	1121115.AXVN01000001_gene1167	1.03e-115	331.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NMLHFLOH_01185	457412.RSAG_01292	2.14e-158	448.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3WS4C@541000|Ruminococcaceae	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
NMLHFLOH_01186	457412.RSAG_01291	6.57e-136	384.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,3WIXW@541000|Ruminococcaceae	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
NMLHFLOH_01187	457412.RSAG_04657	2.12e-53	167.0	2DFIK@1|root,2ZRZQ@2|Bacteria,1W5NZ@1239|Firmicutes,255S4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01188	457412.RSAG_01290	1.12e-287	786.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3WGXA@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
NMLHFLOH_01189	457412.RSAG_01289	2.2e-174	487.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NMLHFLOH_01190	457412.RSAG_01288	6.54e-219	603.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NMLHFLOH_01191	457412.RSAG_01287	4.98e-307	838.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01192	1121115.AXVN01000001_gene1160	6.55e-272	744.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NMLHFLOH_01193	457412.RSAG_01285	1.5e-183	510.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NMLHFLOH_01194	457412.RSAG_01284	6.69e-263	721.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NMLHFLOH_01195	457412.RSAG_01283	2.31e-175	488.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NMLHFLOH_01196	1121115.AXVN01000001_gene1156	0.0	1333.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3XYK0@572511|Blautia	186801|Clostridia	H	precorrin-6B methylase decarboxylase cbiT cbiE	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NMLHFLOH_01197	457412.RSAG_01281	0.0	929.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
NMLHFLOH_01199	1121115.AXVN01000001_gene1153	4.12e-253	694.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3XYPR@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NMLHFLOH_01200	1121115.AXVN01000001_gene1152	0.0	968.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3XYMB@572511|Blautia	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
NMLHFLOH_01201	1121115.AXVN01000001_gene1151	2.31e-147	415.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
NMLHFLOH_01202	1121115.AXVN01000001_gene1150	2.05e-312	852.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3XYXZ@572511|Blautia	186801|Clostridia	K	COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
NMLHFLOH_01203	1121115.AXVN01000001_gene1149	5.75e-208	575.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3XZZQ@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
NMLHFLOH_01204	457412.RSAG_01274	1.49e-114	329.0	COG4720@1|root,COG4720@2|Bacteria,1V8B5@1239|Firmicutes,24J8T@186801|Clostridia,3WJ8C@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NMLHFLOH_01205	1121115.AXVN01000001_gene1147	3.47e-147	414.0	COG0731@1|root,COG0731@2|Bacteria,1UJ6S@1239|Firmicutes,25EWY@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
NMLHFLOH_01206	1121115.AXVN01000001_gene1146	5.03e-67	203.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,3Y0CY@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	czrA	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
NMLHFLOH_01207	1121115.AXVN01000001_gene1145	6.2e-241	662.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,3Y01C@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
NMLHFLOH_01208	457412.RSAG_01252	1.09e-309	845.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NMLHFLOH_01209	457412.RSAG_01251	4.01e-153	430.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3WGAG@541000|Ruminococcaceae	186801|Clostridia	C	system potassium uptake protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NMLHFLOH_01210	457412.RSAG_01250	0.0	991.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3WG8P@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
NMLHFLOH_01211	457412.RSAG_01249	1.33e-165	463.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3WHY5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulatory protein KdpE	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_01212	457412.RSAG_01247	1.96e-187	521.0	2DEAV@1|root,2ZM6Y@2|Bacteria,1V2HI@1239|Firmicutes,24GNN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01213	457412.RSAG_01246	0.0	1122.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3WGP1@541000|Ruminococcaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01214	1121115.AXVN01000001_gene1138	9.23e-293	800.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3XZQJ@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
NMLHFLOH_01215	1121115.AXVN01000001_gene1137	3.62e-111	320.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
NMLHFLOH_01216	1121115.AXVN01000001_gene1136	4.04e-212	586.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3XYIS@572511|Blautia	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
NMLHFLOH_01217	1121115.AXVN01000001_gene1135	0.0	969.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
NMLHFLOH_01218	457412.RSAG_01241	1.03e-236	650.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
NMLHFLOH_01219	1121115.AXVN01000001_gene1133	1.54e-308	840.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NMLHFLOH_01220	1121115.AXVN01000001_gene1132	2.96e-266	728.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NMLHFLOH_01221	457412.RSAG_01238	9.11e-261	714.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NMLHFLOH_01222	457412.RSAG_04660	5.06e-182	511.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NMLHFLOH_01223	1121115.AXVN01000001_gene1129	2.17e-209	578.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3XYV8@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NMLHFLOH_01224	1121115.AXVN01000001_gene1128	0.0	880.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NMLHFLOH_01225	1121115.AXVN01000001_gene1127	1.23e-51	162.0	2FADH@1|root,342MV@2|Bacteria,1VXR1@1239|Firmicutes,252AC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01226	1121115.AXVN01000001_gene1126	0.0	909.0	COG0584@1|root,COG0584@2|Bacteria,1UVUW@1239|Firmicutes,25KN4@186801|Clostridia,3Y249@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
NMLHFLOH_01227	457412.RSAG_01231	3.51e-198	555.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
NMLHFLOH_01229	457412.RSAG_01230	0.0	1224.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG9V@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NMLHFLOH_01230	457412.RSAG_01229	1.64e-74	223.0	2BRJK@1|root,32KIR@2|Bacteria,1US6R@1239|Firmicutes,25A5N@186801|Clostridia,3WR7G@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01231	457412.RSAG_01228	0.0	1736.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NMLHFLOH_01232	457412.RSAG_01227	3.33e-140	396.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3WJC8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NMLHFLOH_01233	1121115.AXVN01000001_gene1120	3.06e-195	540.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NMLHFLOH_01234	1121115.AXVN01000001_gene1119	3.78e-57	177.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
NMLHFLOH_01235	457412.RSAG_01224	0.0	870.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NMLHFLOH_01236	457412.RSAG_01223	3.89e-266	728.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NMLHFLOH_01237	1121115.AXVN01000001_gene1116	3.29e-235	648.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NMLHFLOH_01238	457412.RSAG_01221	2.57e-200	557.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NMLHFLOH_01239	457412.RSAG_01220	3.16e-188	523.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NMLHFLOH_01240	457412.RSAG_01219	1.86e-304	830.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
NMLHFLOH_01241	457412.RSAG_01218	1.17e-100	293.0	2CJ2H@1|root,33QUA@2|Bacteria,1VSMM@1239|Firmicutes,24Z9D@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NMLHFLOH_01242	1121115.AXVN01000052_gene882	2.11e-133	378.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NMLHFLOH_01243	1121115.AXVN01000052_gene881	1.94e-120	343.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NMLHFLOH_01244	1121115.AXVN01000052_gene880	8.46e-133	377.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NMLHFLOH_01245	1121115.AXVN01000052_gene879	2.09e-10	55.5	28U02@1|root,2ZG6F@2|Bacteria,1W5KD@1239|Firmicutes,2551S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01246	1121115.AXVN01000052_gene878	0.0	1120.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
NMLHFLOH_01247	1121115.AXVN01000052_gene877	2.71e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0HD@572511|Blautia	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NMLHFLOH_01248	457412.RSAG_01838	1.64e-209	580.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
NMLHFLOH_01249	1121115.AXVN01000052_gene875	1.29e-298	814.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NMLHFLOH_01250	457412.RSAG_01840	2.01e-244	672.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01251	457412.RSAG_01841	0.0	1415.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WGZR@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_01252	457412.RSAG_01842	0.0	1003.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3WN9A@541000|Ruminococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_01253	457412.RSAG_01843	0.0	1058.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3WI7T@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NMLHFLOH_01254	457412.RSAG_01844	1.68e-192	535.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3WNYS@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_01255	457412.RSAG_01845	1.71e-210	582.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_01256	457412.RSAG_01846	0.0	897.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_01257	1121115.AXVN01000052_gene867	8.28e-295	803.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NMLHFLOH_01259	1121115.AXVN01000177_gene3486	0.0	863.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XZIV@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NMLHFLOH_01260	1121115.AXVN01000177_gene3485	1.65e-266	730.0	COG3584@1|root,COG3584@2|Bacteria,1UVF9@1239|Firmicutes,25AFQ@186801|Clostridia,3XZV0@572511|Blautia	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
NMLHFLOH_01261	1121115.AXVN01000047_gene1270	1.1e-48	155.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24TZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01263	1121115.AXVN01000047_gene1269	1.13e-292	798.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NMLHFLOH_01264	1121115.AXVN01000047_gene1268	6.91e-174	484.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
NMLHFLOH_01265	457412.RSAG_01854	6.5e-183	510.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3WIZ0@541000|Ruminococcaceae	186801|Clostridia	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NMLHFLOH_01266	1121115.AXVN01000047_gene1266	0.0	932.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
NMLHFLOH_01267	1121115.AXVN01000047_gene1265	5.98e-111	319.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01268	1121115.AXVN01000047_gene1264	0.0	984.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NMLHFLOH_01269	1121115.AXVN01000047_gene1263	7.18e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NMLHFLOH_01270	1121115.AXVN01000047_gene1262	1.67e-177	495.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
NMLHFLOH_01271	457412.RSAG_01860	0.0	1331.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
NMLHFLOH_01272	1121115.AXVN01000047_gene1260	6.55e-222	611.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
NMLHFLOH_01273	457412.RSAG_01862	0.0	1004.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NMLHFLOH_01274	1121115.AXVN01000047_gene1258	1.52e-43	141.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3Y0RB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NMLHFLOH_01275	1121115.AXVN01000047_gene1257	4.91e-94	279.0	COG1033@1|root,COG1033@2|Bacteria,1VTBG@1239|Firmicutes,24YPV@186801|Clostridia,3Y1R8@572511|Blautia	186801|Clostridia	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01276	1121115.AXVN01000047_gene1256	0.0	964.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
NMLHFLOH_01277	457412.RSAG_01867	0.0	1318.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
NMLHFLOH_01278	457412.RSAG_01868	0.0	2950.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
NMLHFLOH_01279	1121115.AXVN01000047_gene1253	6.51e-247	678.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
NMLHFLOH_01280	457412.RSAG_01870	6.32e-255	701.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NMLHFLOH_01281	1121115.AXVN01000047_gene1251	2.87e-265	732.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NMLHFLOH_01282	1121115.AXVN01000047_gene1250	6.59e-256	700.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NMLHFLOH_01283	457412.RSAG_01873	1.95e-114	328.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3WJ8H@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
NMLHFLOH_01284	457412.RSAG_01874	8.89e-213	586.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3WHH9@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
NMLHFLOH_01285	457412.RSAG_01875	1.46e-234	645.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NMLHFLOH_01286	457412.RSAG_01882	0.0	1164.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NMLHFLOH_01287	457412.RSAG_01883	7.99e-253	693.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_01288	457412.RSAG_01884	0.0	1172.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NMLHFLOH_01289	457412.RSAG_01885	1.29e-231	636.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UVPR@1239|Firmicutes,25KKF@186801|Clostridia,3WPZY@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_01290	457412.RSAG_01886	1.57e-234	652.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_01291	1121115.AXVN01000085_gene2194	2.94e-289	787.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3XYWH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
NMLHFLOH_01292	1121115.AXVN01000085_gene2193	1.14e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia,3Y1FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_01293	457412.RSAG_01889	1.4e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,1UXJV@1239|Firmicutes,25MIZ@186801|Clostridia,3WQ0J@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_01294	457412.RSAG_01890	1.77e-300	819.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NMLHFLOH_01295	457412.RSAG_01891	0.0	1001.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NMLHFLOH_01296	457412.RSAG_01892	0.0	991.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia,3WJ1J@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NMLHFLOH_01297	457412.RSAG_01893	6.74e-176	492.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK,TP_methylase
NMLHFLOH_01298	457412.RSAG_01894	1.46e-112	323.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NMLHFLOH_01299	1121115.AXVN01000156_gene546	1.47e-94	277.0	2979U@1|root,2ZUHG@2|Bacteria,1W35F@1239|Firmicutes,256C8@186801|Clostridia,3Y0TR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01300	457412.RSAG_04591	0.0	891.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NMLHFLOH_01301	457412.RSAG_01897	2.59e-229	630.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NMLHFLOH_01302	1121115.AXVN01000004_gene1928	6.16e-225	630.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NMLHFLOH_01303	457412.RSAG_00355	0.0	1110.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NMLHFLOH_01304	1121115.AXVN01000004_gene1926	1.4e-262	719.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NMLHFLOH_01305	457412.RSAG_00353	5.66e-278	760.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NMLHFLOH_01306	457412.RSAG_03051	0.0	1441.0	COG5263@1|root,COG5492@1|root,COG5263@2|Bacteria,COG5492@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01307	457412.RSAG_00351	2.36e-245	674.0	COG2197@1|root,COG2197@2|Bacteria,1V1FA@1239|Firmicutes,25FR5@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
NMLHFLOH_01308	1121115.AXVN01000009_gene1456	4.69e-236	649.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NMLHFLOH_01309	457412.RSAG_00349	0.0	1515.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NMLHFLOH_01311	457412.RSAG_04775	0.0	901.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
NMLHFLOH_01312	457412.RSAG_00348	1.63e-280	768.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NMLHFLOH_01313	1121115.AXVN01000009_gene1460	1.14e-197	548.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NMLHFLOH_01314	457412.RSAG_00346	6.25e-171	478.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3WI6W@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10670	BPD_transp_1
NMLHFLOH_01315	457412.RSAG_00345	7.08e-250	686.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NMLHFLOH_01316	457412.RSAG_00344	2.03e-183	511.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3WHJ9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NMLHFLOH_01317	457412.RSAG_00343	0.0	1157.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WHCV@541000|Ruminococcaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NMLHFLOH_01318	457412.RSAG_00342	7.05e-248	680.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WIDW@541000|Ruminococcaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NMLHFLOH_01319	457412.RSAG_00341	0.0	1053.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NMLHFLOH_01320	457412.RSAG_04735	1.08e-266	731.0	COG1146@1|root,COG2006@1|root,COG1146@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,3WHJ8@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
NMLHFLOH_01321	457412.RSAG_00338	1.15e-203	564.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3WH5Y@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NMLHFLOH_01322	457412.RSAG_00337	2.79e-225	619.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3WK1R@541000|Ruminococcaceae	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
NMLHFLOH_01323	1121115.AXVN01000009_gene1470	1.11e-302	825.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NMLHFLOH_01324	457412.RSAG_00335	0.0	1744.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
NMLHFLOH_01325	457412.RSAG_00274	4.31e-177	493.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia,3WKX0@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
NMLHFLOH_01326	457412.RSAG_00273	0.0	1572.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia,3WNZQ@541000|Ruminococcaceae	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
NMLHFLOH_01327	457412.RSAG_00272	6.81e-86	253.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia,3WQNQ@541000|Ruminococcaceae	186801|Clostridia	L	Pfam:DUF310	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
NMLHFLOH_01328	457412.RSAG_00271	2.78e-147	416.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia,3WPKV@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NMLHFLOH_01329	457412.RSAG_00270	2.47e-222	612.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia,3WPNR@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NMLHFLOH_01330	457412.RSAG_00269	6.98e-265	725.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia,3WPY4@541000|Ruminococcaceae	186801|Clostridia	L	RAMP superfamily	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NMLHFLOH_01331	457412.RSAG_00268	8.22e-246	674.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,3WG8Q@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
NMLHFLOH_01332	457412.RSAG_04730	9.69e-72	216.0	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NMLHFLOH_01333	457412.RSAG_00265	0.0	869.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
NMLHFLOH_01335	457412.RSAG_00263	3.16e-162	454.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3WJDW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NMLHFLOH_01336	457412.RSAG_00262	3.96e-253	694.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WG95@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NMLHFLOH_01337	457412.RSAG_00261	0.0	986.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,3WHZ9@541000|Ruminococcaceae	186801|Clostridia	L	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NMLHFLOH_01338	545694.TREPR_0820	9.03e-152	439.0	COG0732@1|root,COG0732@2|Bacteria,2J8T9@203691|Spirochaetes	203691|Spirochaetes	V	Type I R-M system	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NMLHFLOH_01339	483218.BACPEC_01348	6.1e-137	391.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,26AXC@186813|unclassified Clostridiales	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NMLHFLOH_01340	457412.RSAG_00258	2.15e-104	301.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,25CWU@186801|Clostridia,3WS04@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01341	457412.RSAG_00256	0.0	2178.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,3WGBZ@541000|Ruminococcaceae	186801|Clostridia	L	EcoEI R protein C-terminal	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
NMLHFLOH_01342	457412.RSAG_00255	1.17e-146	412.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,3WI1J@541000|Ruminococcaceae	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
NMLHFLOH_01343	457412.RSAG_00254	1.1e-158	444.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,3WKV5@541000|Ruminococcaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
NMLHFLOH_01344	457412.RSAG_00253	2.03e-166	466.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NMLHFLOH_01345	457412.RSAG_00252	0.0	922.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WHMF@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NMLHFLOH_01346	457412.RSAG_00251	2.69e-295	806.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NMLHFLOH_01347	1121115.AXVN01000017_gene266	3.99e-166	464.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_01348	457412.RSAG_00249	0.0	1513.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3WH6Z@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NMLHFLOH_01349	1121115.AXVN01000017_gene264	5.86e-70	214.0	2BBFY@1|root,324Z7@2|Bacteria,1UR44@1239|Firmicutes,258XU@186801|Clostridia,3Y266@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01350	457412.RSAG_00247	0.0	867.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01351	1121115.AXVN01000017_gene262	6.62e-128	363.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NMLHFLOH_01352	1121115.AXVN01000017_gene261	7.69e-279	760.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
NMLHFLOH_01353	457412.RSAG_00243	4.22e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJWK@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_01354	457412.RSAG_00242	7.76e-193	535.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3WIEX@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NMLHFLOH_01355	1121115.AXVN01000017_gene258	1.7e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NMLHFLOH_01356	1121115.AXVN01000017_gene257	0.0	1598.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYHY@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NMLHFLOH_01357	1121115.AXVN01000017_gene256	9.67e-251	689.0	2BDSU@1|root,327GK@2|Bacteria,1UTCR@1239|Firmicutes,258AQ@186801|Clostridia,3Y1YM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01358	1121115.AXVN01000017_gene255	1.85e-205	568.0	2A5RW@1|root,30UGW@2|Bacteria,1US7T@1239|Firmicutes,25A6N@186801|Clostridia,3Y26D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01359	457412.RSAG_00237	0.0	1011.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NMLHFLOH_01360	1121115.AXVN01000008_gene2665	1.07e-299	818.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NMLHFLOH_01361	1121115.AXVN01000008_gene2666	1.48e-200	558.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,3Y2CN@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NMLHFLOH_01362	1121115.AXVN01000008_gene2667	4.82e-121	346.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NMLHFLOH_01363	457412.RSAG_02540	6.15e-161	450.0	COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,25B0D@186801|Clostridia,3WJR6@541000|Ruminococcaceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NMLHFLOH_01364	1121115.AXVN01000008_gene2669	2.91e-189	526.0	COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes,25D5P@186801|Clostridia,3Y1C8@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NMLHFLOH_01365	457412.RSAG_02542	1.49e-228	630.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,3WHIW@541000|Ruminococcaceae	186801|Clostridia	P	PFAM cobalamin (vitamin B12) biosynthesis CbiM protein	-	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
NMLHFLOH_01366	1121115.AXVN01000008_gene2671	1.05e-176	493.0	COG4608@1|root,COG4608@2|Bacteria,1UV6D@1239|Firmicutes,25BCP@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NMLHFLOH_01367	1121115.AXVN01000008_gene2672	4.82e-183	509.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia,3XZCY@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NMLHFLOH_01368	1121115.AXVN01000008_gene2673	0.0	1030.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NMLHFLOH_01369	1121115.AXVN01000008_gene2674	1.18e-195	543.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZRV@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NMLHFLOH_01370	1121115.AXVN01000008_gene2675	5.66e-207	574.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NMLHFLOH_01371	1121115.AXVN01000008_gene2676	3.04e-217	600.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
NMLHFLOH_01372	1121115.AXVN01000008_gene2678	1.05e-296	814.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3XZ1B@572511|Blautia	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
NMLHFLOH_01373	1121115.AXVN01000008_gene2679	5.47e-159	445.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
NMLHFLOH_01374	1121115.AXVN01000008_gene2680	5.67e-199	552.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
NMLHFLOH_01375	457412.RSAG_02553	2.15e-146	412.0	COG2364@1|root,COG2364@2|Bacteria,1V1ZQ@1239|Firmicutes,24GEW@186801|Clostridia,3WRWZ@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
NMLHFLOH_01376	1121115.AXVN01000008_gene2682	1.75e-253	696.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NMLHFLOH_01377	1121115.AXVN01000008_gene2683	1.84e-155	436.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
NMLHFLOH_01378	1121115.AXVN01000008_gene2684	2.46e-271	744.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NMLHFLOH_01379	457412.RSAG_02563	0.0	982.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,3WHIY@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NMLHFLOH_01380	457412.RSAG_02564	3.86e-142	401.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_01381	457412.RSAG_02565	7.77e-301	819.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NMLHFLOH_01382	457412.RSAG_02566	6.85e-132	374.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WKCT@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
NMLHFLOH_01383	1121115.AXVN01000008_gene2688	0.0	1127.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NMLHFLOH_01384	457412.RSAG_02568	9.88e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3WJE7@541000|Ruminococcaceae	186801|Clostridia	E	Small subunit of acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NMLHFLOH_01385	457412.RSAG_02569	1.16e-304	830.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NMLHFLOH_01386	457412.RSAG_02570	3.03e-168	470.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NMLHFLOH_01387	1121115.AXVN01000008_gene2689	3.58e-57	180.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3XZ1J@572511|Blautia	186801|Clostridia	E	COG COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NMLHFLOH_01388	1121115.AXVN01000008_gene2712	8.49e-128	365.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3XZCZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NMLHFLOH_01389	457412.RSAG_02573	1.23e-225	622.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,3WGD5@541000|Ruminococcaceae	186801|Clostridia	EQ	peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
NMLHFLOH_01390	1121115.AXVN01000008_gene2715	7.7e-275	753.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NMLHFLOH_01391	457412.RSAG_02578	4.82e-178	496.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3WG8S@541000|Ruminococcaceae	186801|Clostridia	H	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NMLHFLOH_01392	1121115.AXVN01000008_gene2717	3.7e-16	72.0	2FAZC@1|root,34364@2|Bacteria,1VXA9@1239|Firmicutes,252GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01393	1121115.AXVN01000008_gene2719	0.0	924.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3XZ4X@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NMLHFLOH_01394	1121115.AXVN01000008_gene2720	1.2e-128	365.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3Y0MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
NMLHFLOH_01395	457412.RSAG_02584	0.0	1071.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NMLHFLOH_01396	457412.RSAG_02585	0.0	1659.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,3WI73@541000|Ruminococcaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
NMLHFLOH_01397	457412.RSAG_02586	5.98e-211	583.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_01398	1121115.AXVN01000157_gene539	0.0	1160.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
NMLHFLOH_01399	33035.JPJF01000009_gene1487	3.69e-144	424.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01400	457412.RSAG_02597	0.0	1211.0	COG0426@1|root,COG1773@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1773@2|Bacteria,COG1853@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NMLHFLOH_01401	457412.RSAG_02598	1.45e-281	769.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_01402	457412.RSAG_02599	0.0	1246.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3WHAU@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NMLHFLOH_01403	1121115.AXVN01000089_gene2818	3.76e-206	571.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3Y072@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NMLHFLOH_01404	457412.RSAG_04618	0.0	1873.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,SBP_bac_3
NMLHFLOH_01405	457412.RSAG_02602	0.0	1235.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3WNTR@541000|Ruminococcaceae	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_01406	1121115.AXVN01000089_gene2815	0.0	1382.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3Y1FS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NMLHFLOH_01407	457412.RSAG_02604	1.84e-195	541.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NMLHFLOH_01408	457412.RSAG_02605	4.27e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WH49@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01409	457412.RSAG_02607	1.15e-103	300.0	COG1522@1|root,COG1522@2|Bacteria,1V2P9@1239|Firmicutes,24HFY@186801|Clostridia,3WIU4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
NMLHFLOH_01410	1123313.ATUT01000016_gene633	1.27e-27	105.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,3VRW4@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NMLHFLOH_01411	457412.RSAG_04622	1.03e-37	126.0	COG0534@1|root,COG0534@2|Bacteria,1VZAY@1239|Firmicutes,253UZ@186801|Clostridia	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01412	457412.RSAG_04623	3.68e-212	590.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WHF6@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01413	457412.RSAG_02610	2.63e-36	122.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,24K97@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01414	411902.CLOBOL_05506	1.69e-183	517.0	2CIG8@1|root,2Z7UI@2|Bacteria,1TRB9@1239|Firmicutes,24CHU@186801|Clostridia,2208F@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01415	411902.CLOBOL_05507	2.5e-126	359.0	2CS32@1|root,303NF@2|Bacteria,1TUWZ@1239|Firmicutes,25M7G@186801|Clostridia,220Y6@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01416	411902.CLOBOL_05508	4.92e-90	264.0	2AY78@1|root,31Q9C@2|Bacteria,1V75X@1239|Firmicutes,24I58@186801|Clostridia,2232W@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01417	411902.CLOBOL_05509	1.33e-166	466.0	28HST@1|root,2Z7ZU@2|Bacteria,1TPCE@1239|Firmicutes,24AG2@186801|Clostridia,220SZ@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01418	411902.CLOBOL_05510	1.62e-201	560.0	2DBP9@1|root,2ZA85@2|Bacteria,1UXYH@1239|Firmicutes,24B1P@186801|Clostridia,221X7@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01419	411902.CLOBOL_05511	1.12e-268	736.0	COG0791@1|root,COG0791@2|Bacteria,1UYV9@1239|Firmicutes	1239|Firmicutes	M	NlpC P60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NMLHFLOH_01420	411902.CLOBOL_05512	0.0	1911.0	COG3451@1|root,COG3451@2|Bacteria,1TQGE@1239|Firmicutes,24ACY@186801|Clostridia,21Y2H@1506553|Lachnoclostridium	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NMLHFLOH_01422	411902.CLOBOL_05514	1.85e-110	320.0	28IFT@1|root,2Z8HE@2|Bacteria,1US7D@1239|Firmicutes,25A69@186801|Clostridia,2218G@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01423	411902.CLOBOL_05515	2.95e-266	729.0	28IDZ@1|root,2Z8G4@2|Bacteria,1V015@1239|Firmicutes,249QY@186801|Clostridia,220WE@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01424	411902.CLOBOL_05517	0.0	1114.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,21ZE2@1506553|Lachnoclostridium	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
NMLHFLOH_01425	411902.CLOBOL_05518	1.62e-230	635.0	COG0539@1|root,COG0539@2|Bacteria,1UY0Q@1239|Firmicutes,24B4G@186801|Clostridia,21Y5T@1506553|Lachnoclostridium	186801|Clostridia	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NMLHFLOH_01426	411902.CLOBOL_05519	2.64e-143	405.0	COG5340@1|root,COG5340@2|Bacteria,1V3P6@1239|Firmicutes,24HEC@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01427	411902.CLOBOL_05520	1.43e-220	608.0	COG2253@1|root,COG2253@2|Bacteria,1U5S2@1239|Firmicutes,25M66@186801|Clostridia,223FU@1506553|Lachnoclostridium	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
NMLHFLOH_01428	411902.CLOBOL_05521	5.8e-162	454.0	2BE4W@1|root,327VK@2|Bacteria,1UTSS@1239|Firmicutes,25468@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01429	411902.CLOBOL_05522	2.68e-67	204.0	COG1813@1|root,COG1813@2|Bacteria,1UIB5@1239|Firmicutes	1239|Firmicutes	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
NMLHFLOH_01430	411902.CLOBOL_05523	6.49e-90	263.0	2C3VQ@1|root,2ZCBB@2|Bacteria,1V2NF@1239|Firmicutes,25DGE@186801|Clostridia,2231A@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4320)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4320
NMLHFLOH_01431	411902.CLOBOL_05524	1.6e-113	325.0	28K3M@1|root,2Z9SR@2|Bacteria,1UZ3W@1239|Firmicutes,24D5R@186801|Clostridia,2234E@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01432	411902.CLOBOL_05525	7.24e-121	346.0	2DJUN@1|root,307E0@2|Bacteria,1U1I2@1239|Firmicutes,25AM1@186801|Clostridia,223H9@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01433	411902.CLOBOL_05526	0.0	1096.0	COG1572@1|root,COG1572@2|Bacteria,1TR48@1239|Firmicutes,24ADC@186801|Clostridia,2225D@1506553|Lachnoclostridium	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01434	411902.CLOBOL_05527	8.01e-102	295.0	COG1989@1|root,COG1989@2|Bacteria,1TTIN@1239|Firmicutes,25NJK@186801|Clostridia,223EU@1506553|Lachnoclostridium	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
NMLHFLOH_01435	411902.CLOBOL_05529	1.65e-186	520.0	COG3745@1|root,COG3745@2|Bacteria,1TQRH@1239|Firmicutes,24BZT@186801|Clostridia,221S5@1506553|Lachnoclostridium	186801|Clostridia	U	Flp pilus assembly protein RcpC/CpaB	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
NMLHFLOH_01436	411902.CLOBOL_05530	4.85e-186	517.0	COG0455@1|root,COG0455@2|Bacteria,1TPJA@1239|Firmicutes,24A7K@186801|Clostridia,21Z2K@1506553|Lachnoclostridium	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01437	411902.CLOBOL_05531	0.0	890.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,21ZQ7@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG4962 Flp pilus assembly protein, ATPase CpaF	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NMLHFLOH_01438	411902.CLOBOL_05532	2.44e-213	590.0	COG4965@1|root,COG4965@2|Bacteria,1TS4U@1239|Firmicutes,248K2@186801|Clostridia,221ZT@1506553|Lachnoclostridium	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01439	411902.CLOBOL_05533	1.61e-195	543.0	COG2064@1|root,COG2064@2|Bacteria,1TUMZ@1239|Firmicutes,2495N@186801|Clostridia,222BW@1506553|Lachnoclostridium	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	-
NMLHFLOH_01440	411902.CLOBOL_05534	1.33e-75	226.0	2E4MF@1|root,32ZGD@2|Bacteria,1VEIK@1239|Firmicutes,24QUQ@186801|Clostridia,221E2@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01441	411902.CLOBOL_05536	2.41e-85	250.0	29V85@1|root,30GN2@2|Bacteria,1UGB8@1239|Firmicutes,25NQ3@186801|Clostridia,223N6@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01442	411902.CLOBOL_05538	7.58e-98	283.0	2C7AV@1|root,32S15@2|Bacteria,1VDFV@1239|Firmicutes,25HQ3@186801|Clostridia,2216S@1506553|Lachnoclostridium	186801|Clostridia	S	zinc-finger-containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3268
NMLHFLOH_01443	411902.CLOBOL_05540	4.1e-130	369.0	2BYWM@1|root,30J2M@2|Bacteria,1US29@1239|Firmicutes,25A0M@186801|Clostridia,223M1@1506553|Lachnoclostridium	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01444	411902.CLOBOL_05541	1.59e-136	386.0	28J1V@1|root,30GG9@2|Bacteria,1UFZB@1239|Firmicutes,25N1H@186801|Clostridia,223JT@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01445	411902.CLOBOL_05542	2.5e-259	709.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	CP_0264	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox,TIR_2
NMLHFLOH_01446	411902.CLOBOL_05543	4.08e-98	285.0	2BXGH@1|root,32R1A@2|Bacteria,1V8FX@1239|Firmicutes,24JT8@186801|Clostridia	186801|Clostridia	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
NMLHFLOH_01447	411902.CLOBOL_05544	1.45e-198	550.0	2CKKE@1|root,2ZC1Q@2|Bacteria,1V2EX@1239|Firmicutes,25MZG@186801|Clostridia,2238G@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01448	411902.CLOBOL_05545	0.0	1184.0	COG0714@1|root,COG0714@2|Bacteria,1UZ11@1239|Firmicutes,25M2K@186801|Clostridia,222HX@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01450	411902.CLOBOL_05547	0.0	1352.0	COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,24ASV@186801|Clostridia,222B1@1506553|Lachnoclostridium	186801|Clostridia	P	Cobalamin biosynthesis protein CobT VWA domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NMLHFLOH_01451	411902.CLOBOL_05548	6.14e-155	435.0	28MBF@1|root,2ZAPY@2|Bacteria,1UZPT@1239|Firmicutes,24DCB@186801|Clostridia,22332@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01452	411902.CLOBOL_05549	9.43e-118	338.0	COG2002@1|root,COG2002@2|Bacteria	2|Bacteria	K	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin,SpoVT_C
NMLHFLOH_01454	411902.CLOBOL_05551	8.83e-112	321.0	2A951@1|root,30GKP@2|Bacteria,1UG8X@1239|Firmicutes,25NJ1@186801|Clostridia,221I2@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01455	411902.CLOBOL_05552	0.0	1350.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,21YNR@1506553|Lachnoclostridium	186801|Clostridia	H	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NMLHFLOH_01456	411902.CLOBOL_05553	0.0	907.0	COG1373@1|root,COG1373@2|Bacteria,1UZD0@1239|Firmicutes,25EI0@186801|Clostridia,21ZMF@1506553|Lachnoclostridium	186801|Clostridia	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NMLHFLOH_01458	1235792.C808_02592	1.19e-21	86.7	2CDC9@1|root,32RXG@2|Bacteria,1VA39@1239|Firmicutes,24MYY@186801|Clostridia,27SAC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NMLHFLOH_01459	411902.CLOBOL_05556	2.07e-148	417.0	COG1961@1|root,COG1961@2|Bacteria,1TQAX@1239|Firmicutes,24B05@186801|Clostridia,220QB@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
NMLHFLOH_01460	411902.CLOBOL_05557	2.78e-37	125.0	2DKB2@1|root,3092J@2|Bacteria,1U4C4@1239|Firmicutes,25PCH@186801|Clostridia,221G9@1506553|Lachnoclostridium	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NMLHFLOH_01461	411902.CLOBOL_05558	8.31e-98	286.0	2989M@1|root,2ZVF6@2|Bacteria,1V5JI@1239|Firmicutes,24IVT@186801|Clostridia,223G9@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NMLHFLOH_01462	411902.CLOBOL_05559	8.56e-59	182.0	COG1476@1|root,COG1476@2|Bacteria,1V4DH@1239|Firmicutes,24HSN@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_01463	411902.CLOBOL_05560	7.16e-118	338.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,21XPZ@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG3344 Retron-type reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NMLHFLOH_01464	411902.CLOBOL_05561	2.18e-170	477.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,21Y17@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NMLHFLOH_01465	411902.CLOBOL_05562	6.36e-39	131.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	-	-	3.6.3.25	ko:K06020,ko:K06147	-	-	-	-	ko00000,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01466	411902.CLOBOL_05564	3.16e-125	356.0	2EGV8@1|root,33AME@2|Bacteria,1VMWS@1239|Firmicutes,24XFC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
NMLHFLOH_01467	411902.CLOBOL_05566	8.47e-207	572.0	2DVQ8@1|root,32UZY@2|Bacteria,1VD4W@1239|Firmicutes,24NJS@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3137)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3137
NMLHFLOH_01468	411902.CLOBOL_05567	6.54e-222	612.0	2EKJR@1|root,33E9K@2|Bacteria,1VMT6@1239|Firmicutes,24WZX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01469	411902.CLOBOL_05568	0.0	912.0	2DF9D@1|root,2ZQZS@2|Bacteria,1V5NP@1239|Firmicutes,24IRE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01471	411902.CLOBOL_05570	7.44e-220	606.0	29VTM@1|root,3411D@2|Bacteria,1VY0M@1239|Firmicutes,251RY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01472	411902.CLOBOL_05572	2.42e-238	653.0	2C38K@1|root,33R6C@2|Bacteria,1VS79@1239|Firmicutes,24Y9W@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01473	411902.CLOBOL_05574	5.79e-181	504.0	2FCGB@1|root,344JS@2|Bacteria,1VYKK@1239|Firmicutes,253KC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01474	411902.CLOBOL_05575	3.1e-51	161.0	2E7M2@1|root,33230@2|Bacteria,1VIM8@1239|Firmicutes,24RAV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NMLHFLOH_01475	411902.CLOBOL_05576	0.0	1638.0	COG2909@1|root,COG2909@2|Bacteria,1TT0M@1239|Firmicutes,24BMZ@186801|Clostridia,21XR1@1506553|Lachnoclostridium	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_22,GerE
NMLHFLOH_01476	411902.CLOBOL_05577	4.47e-260	714.0	COG5433@1|root,COG5433@2|Bacteria,1UZWV@1239|Firmicutes,24DPT@186801|Clostridia,222BK@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
NMLHFLOH_01477	411902.CLOBOL_05578	1.32e-137	390.0	2B876@1|root,321FR@2|Bacteria,1UEHH@1239|Firmicutes,25JEK@186801|Clostridia,222GW@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01478	411902.CLOBOL_05579	1.15e-192	534.0	COG3279@1|root,COG3279@2|Bacteria,1VASG@1239|Firmicutes,24N4B@186801|Clostridia,221E0@1506553|Lachnoclostridium	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,SnoaL_3
NMLHFLOH_01479	411902.CLOBOL_05580	1.81e-256	704.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,21YEK@1506553|Lachnoclostridium	186801|Clostridia	L	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_01480	411902.CLOBOL_05584	0.0	1103.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,21XNM@1506553|Lachnoclostridium	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01481	411902.CLOBOL_05585	0.0	1144.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,21YRP@1506553|Lachnoclostridium	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01482	411902.CLOBOL_05586	2.7e-147	414.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,220QI@1506553|Lachnoclostridium	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_01483	1121115.AXVN01000081_gene3050	2.99e-177	500.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NMLHFLOH_01484	1121115.AXVN01000081_gene3051	0.0	944.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NMLHFLOH_01485	1121115.AXVN01000081_gene3052	6.52e-292	796.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3XYS6@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
NMLHFLOH_01487	1121115.AXVN01000081_gene3053	1.13e-171	480.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3XZ2M@572511|Blautia	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
NMLHFLOH_01488	1121115.AXVN01000081_gene3054	3.23e-279	768.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NMLHFLOH_01489	1121115.AXVN01000081_gene3055	1.98e-109	318.0	COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_01490	1121115.AXVN01000206_gene3748	6.68e-203	568.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes,24KBY@186801|Clostridia,3Y1U0@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_01491	1121115.AXVN01000116_gene2324	0.0	1462.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
NMLHFLOH_01493	457412.RSAG_01750	0.0	1335.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
NMLHFLOH_01494	1121115.AXVN01000116_gene2327	0.0	874.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NMLHFLOH_01495	1121115.AXVN01000071_gene3935	7.49e-176	490.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NMLHFLOH_01496	457412.RSAG_01747	0.0	865.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NMLHFLOH_01497	457412.RSAG_01746	0.0	1588.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NMLHFLOH_01498	457412.RSAG_01745	0.0	874.0	COG2367@1|root,COG2367@2|Bacteria,1VCFX@1239|Firmicutes,24D4X@186801|Clostridia,3WKRB@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NMLHFLOH_01499	457412.RSAG_01744	1.86e-304	830.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia,3WI4U@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
NMLHFLOH_01500	457412.RSAG_01743	1.05e-112	323.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
NMLHFLOH_01501	457412.RSAG_01742	0.0	926.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3WHD2@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
NMLHFLOH_01502	457412.RSAG_01741	5.2e-108	311.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
NMLHFLOH_01503	457412.RSAG_01740	5.22e-173	483.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3WGPU@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
NMLHFLOH_01504	457412.RSAG_01738	3.32e-135	383.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3WJVB@541000|Ruminococcaceae	186801|Clostridia	K	RNA polymerase sigma factor, sigma-70 family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
NMLHFLOH_01506	457412.RSAG_01737	7.57e-124	352.0	COG4636@1|root,COG4636@2|Bacteria,1TT9W@1239|Firmicutes,24ANM@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_01507	457412.RSAG_01736	0.0	1137.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NMLHFLOH_01508	1121115.AXVN01000042_gene3008	9.51e-39	134.0	2F1AC@1|root,33UBB@2|Bacteria,1VUR2@1239|Firmicutes,2503K@186801|Clostridia,3Y24T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01509	457412.RSAG_01734	2.97e-137	388.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NMLHFLOH_01510	1121115.AXVN01000042_gene3010	5.49e-163	455.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NMLHFLOH_01511	1121115.AXVN01000042_gene3011	9.4e-192	532.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NMLHFLOH_01512	457412.RSAG_01731	2.36e-51	162.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3WKYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01513	457412.RSAG_01730	0.0	1528.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
NMLHFLOH_01514	457412.RSAG_01729	0.0	1361.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
NMLHFLOH_01515	1121115.AXVN01000042_gene3015	7.42e-75	223.0	COG0745@1|root,COG0745@2|Bacteria,1UK3F@1239|Firmicutes,25FI6@186801|Clostridia,3Y0KY@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NMLHFLOH_01516	1121115.AXVN01000042_gene3016	2.76e-120	343.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01517	457412.RSAG_01726	1.51e-198	550.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3WI03@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NMLHFLOH_01518	1121115.AXVN01000042_gene3018	7.64e-61	192.0	2DUBB@1|root,33PT0@2|Bacteria,1VSM4@1239|Firmicutes,24YVT@186801|Clostridia,3Y0NE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01519	1121115.AXVN01000042_gene3019	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NMLHFLOH_01520	1121115.AXVN01000042_gene3020	0.0	864.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NMLHFLOH_01521	1121115.AXVN01000042_gene3021	4.46e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NMLHFLOH_01522	1121115.AXVN01000042_gene3022	2.94e-192	533.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NMLHFLOH_01523	457412.RSAG_01720	2.17e-213	589.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3WGC5@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NMLHFLOH_01524	457412.RSAG_01719	2.7e-161	451.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3WGS1@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NMLHFLOH_01525	1121115.AXVN01000042_gene3025	6.09e-24	90.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01526	457412.RSAG_01717	3.03e-106	306.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3WK49@541000|Ruminococcaceae	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NMLHFLOH_01527	1121115.AXVN01000042_gene3027	4.05e-64	196.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01528	1121115.AXVN01000042_gene3028	0.0	1356.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
NMLHFLOH_01529	1121115.AXVN01000042_gene3029	1.31e-109	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NMLHFLOH_01530	1121115.AXVN01000042_gene3030	4.78e-249	683.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NMLHFLOH_01531	457412.RSAG_01712	6.4e-149	419.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3WIAG@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
NMLHFLOH_01532	457412.RSAG_01711	2.84e-315	857.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3WGPD@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NMLHFLOH_01533	457412.RSAG_01710	9.73e-179	498.0	28NW4@1|root,32MWE@2|Bacteria,1TUAZ@1239|Firmicutes,259BP@186801|Clostridia,3WPWQ@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
NMLHFLOH_01534	457412.RSAG_01709	9.51e-81	239.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3WJKW@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NMLHFLOH_01535	457412.RSAG_01708	0.0	1556.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WGYI@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the ClpA ClpB family	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
NMLHFLOH_01536	1121115.AXVN01000042_gene3037	1.4e-90	265.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01537	457412.RSAG_01706	0.0	889.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3WG8G@541000|Ruminococcaceae	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NMLHFLOH_01538	457412.RSAG_01705	1.02e-158	444.0	COG0637@1|root,COG0637@2|Bacteria,1V1IW@1239|Firmicutes,24FZZ@186801|Clostridia,3WRQ7@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	CpXC,HAD_2
NMLHFLOH_01539	457412.RSAG_01704	0.0	871.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WH3J@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NMLHFLOH_01540	1121115.AXVN01000042_gene3041	2.75e-210	580.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3Y06U@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_01541	1121115.AXVN01000046_gene2959	2.1e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NMLHFLOH_01542	1262449.CP6013_0673	6.39e-10	65.9	COG1388@1|root,COG2866@1|root,COG3409@1|root,COG1388@2|Bacteria,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,36H9C@31979|Clostridiaceae	186801|Clostridia	EM	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
NMLHFLOH_01543	1151292.QEW_0802	6.74e-42	160.0	COG4219@1|root,COG4219@2|Bacteria,1TQ0K@1239|Firmicutes,24AVI@186801|Clostridia,25S0H@186804|Peptostreptococcaceae	186801|Clostridia	KT	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NMLHFLOH_01544	1449050.JNLE01000003_gene1371	6.6e-46	151.0	COG3682@1|root,COG3682@2|Bacteria,1V7DH@1239|Firmicutes,24JAQ@186801|Clostridia,36MEY@31979|Clostridiaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NMLHFLOH_01545	1121115.AXVN01000046_gene2961	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NMLHFLOH_01546	1121115.AXVN01000046_gene2962	3.05e-184	511.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NMLHFLOH_01547	1121115.AXVN01000046_gene2963	4.7e-156	437.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NMLHFLOH_01548	457412.RSAG_02864	1.31e-302	827.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NMLHFLOH_01549	1121115.AXVN01000046_gene2965	2.1e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NMLHFLOH_01550	1121115.AXVN01000046_gene2966	1.2e-33	115.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NMLHFLOH_01551	1121115.AXVN01000046_gene2967	1.46e-112	323.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NMLHFLOH_01552	1121115.AXVN01000046_gene2968	1.22e-77	231.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NMLHFLOH_01553	457412.RSAG_02859	4.24e-110	318.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3WIFT@541000|Ruminococcaceae	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NMLHFLOH_01554	1121115.AXVN01000046_gene2970	8.56e-90	263.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NMLHFLOH_01555	1121115.AXVN01000046_gene2971	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NMLHFLOH_01556	457412.RSAG_02856	9.39e-123	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NMLHFLOH_01557	1121115.AXVN01000046_gene2973	2.29e-64	196.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NMLHFLOH_01558	1121115.AXVN01000046_gene2974	1.8e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3XZZG@572511|Blautia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NMLHFLOH_01559	457412.RSAG_02853	4.6e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NMLHFLOH_01560	457412.RSAG_02852	3.99e-36	122.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NMLHFLOH_01561	1121115.AXVN01000046_gene2977	1.88e-101	293.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NMLHFLOH_01562	1121115.AXVN01000046_gene2978	3.41e-151	425.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NMLHFLOH_01563	1121115.AXVN01000046_gene2979	5.64e-84	248.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NMLHFLOH_01564	1121115.AXVN01000046_gene2980	1.77e-61	188.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NMLHFLOH_01565	457412.RSAG_02847	3.72e-200	554.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NMLHFLOH_01566	1121115.AXVN01000046_gene2982	7.84e-61	187.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3Y06M@572511|Blautia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
NMLHFLOH_01567	1121115.AXVN01000046_gene2983	3.27e-134	381.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NMLHFLOH_01568	1121115.AXVN01000046_gene2984	1.77e-149	420.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NMLHFLOH_01569	1121115.AXVN01000046_gene2985	3.91e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NMLHFLOH_01570	1121115.AXVN01000046_gene2986	3.88e-234	649.0	COG0681@1|root,COG0681@2|Bacteria,1VGJ6@1239|Firmicutes,24SUY@186801|Clostridia,3Y28M@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01571	1121115.AXVN01000046_gene2987	1.27e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3Y2CC@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NMLHFLOH_01572	1121115.AXVN01000046_gene2988	3.83e-232	640.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NMLHFLOH_01573	1121115.AXVN01000046_gene2989	2.01e-211	584.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3XZM6@572511|Blautia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NMLHFLOH_01574	457412.RSAG_02838	3.2e-212	587.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NMLHFLOH_01575	1121115.AXVN01000057_gene2532	8.08e-100	289.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,3Y0C4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
NMLHFLOH_01576	457412.RSAG_02836	2.93e-107	309.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3WJNA@541000|Ruminococcaceae	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NMLHFLOH_01577	457412.RSAG_02835	1.59e-268	734.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NMLHFLOH_01578	457412.RSAG_02834	2.69e-79	235.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NMLHFLOH_01579	1121115.AXVN01000057_gene2528	1.2e-144	407.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,3XZTN@572511|Blautia	186801|Clostridia	S	Psort location	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
NMLHFLOH_01580	1121115.AXVN01000057_gene2527	3.47e-109	315.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3Y02K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
NMLHFLOH_01582	1121115.AXVN01000057_gene2526	4.08e-157	442.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NMLHFLOH_01583	1121115.AXVN01000057_gene2525	1.5e-96	281.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NMLHFLOH_01584	1121115.AXVN01000057_gene2524	2.76e-70	211.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NMLHFLOH_01585	457412.RSAG_02828	1.92e-264	731.0	COG0457@1|root,COG0457@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
NMLHFLOH_01586	1121115.AXVN01000057_gene2522	3.2e-27	99.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01587	457412.RSAG_02826	5.2e-315	857.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGW8@541000|Ruminococcaceae	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NMLHFLOH_01588	457412.RSAG_02825	0.0	1355.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NMLHFLOH_01589	1121115.AXVN01000057_gene2519	0.0	1807.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NMLHFLOH_01590	457412.RSAG_02822	1.36e-287	784.0	COG2159@1|root,COG2159@2|Bacteria,1UZI6@1239|Firmicutes,24EHD@186801|Clostridia,3WKR9@541000|Ruminococcaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
NMLHFLOH_01591	1121115.AXVN01000057_gene2517	0.0	1611.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3XYHV@572511|Blautia	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NMLHFLOH_01592	457412.RSAG_02820	9e-166	464.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_01593	1121115.AXVN01000057_gene2515	8.59e-313	863.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01594	457412.RSAG_02818	0.0	1373.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Polysacc_lyase,SLH
NMLHFLOH_01595	457412.RSAG_02817	4.38e-43	140.0	2E98V@1|root,333H5@2|Bacteria,1VI8K@1239|Firmicutes,24RMD@186801|Clostridia	186801|Clostridia	S	BhlA holin family	-	-	-	-	-	-	-	-	-	-	-	-	Holin_BhlA
NMLHFLOH_01596	457412.RSAG_02816	5.47e-125	355.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01597	457412.RSAG_02815	0.0	1781.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3WIW0@541000|Ruminococcaceae	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
NMLHFLOH_01599	457412.RSAG_02814	0.0	948.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,24JUC@186801|Clostridia,3WJ4K@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_01600	457412.RSAG_02813	8.64e-163	456.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,25KED@186801|Clostridia,3WM6U@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_01601	1121115.AXVN01000051_gene811	2.11e-76	234.0	2EHNM@1|root,33BEE@2|Bacteria,1VNIH@1239|Firmicutes,24PUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01602	457412.RSAG_02811	5.61e-71	214.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NMLHFLOH_01603	457412.RSAG_02810	1.95e-221	610.0	COG0791@1|root,COG0791@2|Bacteria,1V9RT@1239|Firmicutes,24EYR@186801|Clostridia,3WJFG@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,NLPC_P60,PG_binding_1
NMLHFLOH_01605	457412.RSAG_02808	0.0	1140.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Flg_new,LRR_5,TcdB_toxin_midN
NMLHFLOH_01606	457412.RSAG_04775	0.0	901.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
NMLHFLOH_01607	457412.RSAG_01324	3.52e-56	185.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_01608	1121115.AXVN01000016_gene3669	2.78e-167	468.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3Y05M@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
NMLHFLOH_01609	457412.RSAG_02380	8.05e-157	440.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NMLHFLOH_01610	457412.RSAG_02379	3.21e-211	583.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
NMLHFLOH_01611	1121115.AXVN01000016_gene3672	0.0	1287.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NMLHFLOH_01612	457412.RSAG_02377	1.33e-172	482.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NMLHFLOH_01613	1121115.AXVN01000016_gene3674	8.97e-252	690.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NMLHFLOH_01614	457412.RSAG_02375	0.0	899.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NMLHFLOH_01615	1121115.AXVN01000016_gene3676	1.08e-149	422.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3XZPM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.26	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NMLHFLOH_01616	457412.RSAG_02373	3.27e-227	625.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NMLHFLOH_01617	1121115.AXVN01000016_gene3678	1.18e-108	313.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NMLHFLOH_01618	457412.RSAG_02371	0.0	1441.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NMLHFLOH_01619	457412.RSAG_02370	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3WHE3@541000|Ruminococcaceae	186801|Clostridia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NMLHFLOH_01620	1121115.AXVN01000016_gene3681	0.0	1038.0	2EX8G@1|root,33QJ9@2|Bacteria,1VTVN@1239|Firmicutes,25FHM@186801|Clostridia,3Y0FY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01621	457412.RSAG_02368	1.72e-215	595.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3WHV4@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NMLHFLOH_01622	1121115.AXVN01000016_gene3683	0.0	1450.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NMLHFLOH_01623	457412.RSAG_02366	2.37e-195	546.0	2EYFJ@1|root,33RPG@2|Bacteria,1VSB2@1239|Firmicutes,24ZFW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01624	1121115.AXVN01000016_gene3686	1.94e-245	673.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
NMLHFLOH_01625	457412.RSAG_02364	9.04e-98	284.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3WKBA@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
NMLHFLOH_01626	457412.RSAG_02363	1.04e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WND9@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
NMLHFLOH_01627	457412.RSAG_02362	1.62e-172	481.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NMLHFLOH_01628	457412.RSAG_04630	2.46e-157	442.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3WHWM@541000|Ruminococcaceae	186801|Clostridia	P	acid ABC transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
NMLHFLOH_01629	457412.RSAG_04631	3.25e-180	502.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NMLHFLOH_01630	1121115.AXVN01000016_gene3692	1.94e-204	565.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NMLHFLOH_01631	1121115.AXVN01000016_gene3693	1.17e-58	182.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,3Y0E3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
NMLHFLOH_01632	457412.RSAG_02358	1.17e-158	446.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3WIDD@541000|Ruminococcaceae	186801|Clostridia	E	AzlC protein	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
NMLHFLOH_01633	457412.RSAG_02357	2.47e-211	587.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NMLHFLOH_01634	1121115.AXVN01000016_gene3696	3.69e-101	292.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,25MW0@186801|Clostridia,3Y26V@572511|Blautia	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
NMLHFLOH_01635	457412.RSAG_02355	9.32e-191	531.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
NMLHFLOH_01636	1121115.AXVN01000036_gene2404	7.8e-315	857.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NMLHFLOH_01637	1121115.AXVN01000036_gene2405	3.9e-269	735.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NMLHFLOH_01638	457412.RSAG_02352	7.05e-219	604.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NMLHFLOH_01639	1121115.AXVN01000036_gene2407	4.8e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NMLHFLOH_01640	1121115.AXVN01000036_gene2408	1.97e-96	281.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01641	457412.RSAG_02349	0.0	1610.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WGUQ@541000|Ruminococcaceae	186801|Clostridia	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
NMLHFLOH_01642	1121115.AXVN01000036_gene2410	1.25e-284	779.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NMLHFLOH_01643	1121115.AXVN01000036_gene2411	2.56e-248	682.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia,3XYS1@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
NMLHFLOH_01644	1121115.AXVN01000036_gene2412	0.0	886.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NMLHFLOH_01645	1121115.AXVN01000036_gene2413	8.93e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYIA@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NMLHFLOH_01646	1121115.AXVN01000036_gene2414	1.09e-249	686.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NMLHFLOH_01647	1121115.AXVN01000036_gene2415	8.39e-233	640.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NMLHFLOH_01648	1121115.AXVN01000036_gene2416	4.95e-221	610.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NMLHFLOH_01649	1121115.AXVN01000036_gene2417	1.02e-46	149.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NMLHFLOH_01650	457412.RSAG_02341	0.0	898.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3WGZQ@541000|Ruminococcaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
NMLHFLOH_01651	457412.RSAG_02340	3.75e-109	315.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3WJEQ@541000|Ruminococcaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
NMLHFLOH_01652	1121115.AXVN01000036_gene2428	2.32e-261	715.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NMLHFLOH_01653	1121115.AXVN01000036_gene2429	0.0	1300.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NMLHFLOH_01654	1121115.AXVN01000036_gene2430	0.0	1705.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
NMLHFLOH_01655	1121115.AXVN01000036_gene2431	1.47e-241	664.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NMLHFLOH_01656	1121115.AXVN01000036_gene2432	0.0	890.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3Y0CH@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_01657	1121115.AXVN01000036_gene2433	2.44e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_01658	1121115.AXVN01000036_gene2434	3.53e-200	555.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_01659	1121115.AXVN01000011_gene3447	2.85e-60	192.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NMLHFLOH_01660	457412.RSAG_00533	3.4e-117	334.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NMLHFLOH_01661	457412.RSAG_00532	8.41e-235	645.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,3WJVS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01662	1121115.AXVN01000029_gene653	2.56e-178	498.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3XZ9G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
NMLHFLOH_01663	457412.RSAG_00530	2.82e-207	574.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGJI@541000|Ruminococcaceae	186801|Clostridia	S	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
NMLHFLOH_01664	1121115.AXVN01000029_gene651	1.05e-225	623.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
NMLHFLOH_01665	1121115.AXVN01000029_gene650	7.41e-157	442.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
NMLHFLOH_01666	457412.RSAG_00527	2.54e-144	406.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3WITP@541000|Ruminococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NMLHFLOH_01667	1121115.AXVN01000029_gene648	2.26e-286	785.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XZS0@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NMLHFLOH_01668	1121115.AXVN01000029_gene647	3.98e-253	706.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01669	1121115.AXVN01000029_gene646	8.43e-73	219.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
NMLHFLOH_01670	1121115.AXVN01000029_gene645	1.83e-20	81.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
NMLHFLOH_01671	1121115.AXVN01000029_gene644	0.0	943.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NMLHFLOH_01672	1121115.AXVN01000029_gene643	0.0	1439.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
NMLHFLOH_01673	1121115.AXVN01000029_gene642	0.0	1112.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NMLHFLOH_01674	1121115.AXVN01000029_gene641	4.17e-119	340.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NMLHFLOH_01675	1121115.AXVN01000029_gene640	0.0	1501.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NMLHFLOH_01676	1121115.AXVN01000029_gene639	1.59e-156	438.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3Y04N@572511|Blautia	186801|Clostridia	S	COG COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NMLHFLOH_01677	457412.RSAG_00516	0.0	994.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NMLHFLOH_01678	457412.RSAG_00515	8.1e-160	447.0	COG2206@1|root,COG2206@2|Bacteria,1V54U@1239|Firmicutes,24HUA@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
NMLHFLOH_01679	1121115.AXVN01000029_gene636	3.94e-291	795.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NMLHFLOH_01680	1121115.AXVN01000029_gene635	0.0	1170.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NMLHFLOH_01681	1121115.AXVN01000029_gene634	4.97e-170	476.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3XZD6@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
NMLHFLOH_01682	1121115.AXVN01000029_gene633	3.13e-274	752.0	2F32Z@1|root,33VY0@2|Bacteria,1VRWP@1239|Firmicutes,25PV9@186801|Clostridia,3XZBM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01683	457412.RSAG_00510	9.91e-307	842.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3WI4Z@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NMLHFLOH_01684	457412.RSAG_00509	7.73e-155	435.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_01685	1121115.AXVN01000029_gene630	0.0	1242.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3XYTA@572511|Blautia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
NMLHFLOH_01686	1121115.AXVN01000026_gene983	1.88e-290	794.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NMLHFLOH_01687	1121115.AXVN01000026_gene984	2.97e-54	169.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NMLHFLOH_01688	1121115.AXVN01000026_gene985	0.0	1016.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NMLHFLOH_01689	457412.RSAG_00504	7.78e-202	559.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3WGV0@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NMLHFLOH_01690	1121115.AXVN01000026_gene987	0.0	1166.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NMLHFLOH_01691	457412.RSAG_00502	9.54e-304	828.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
NMLHFLOH_01692	457412.RSAG_00501	2.28e-148	428.0	2CAM6@1|root,33TP6@2|Bacteria,1VTBW@1239|Firmicutes,24Z6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01693	457412.RSAG_00500	1.91e-151	426.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3WITI@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NMLHFLOH_01694	457412.RSAG_00499	4.47e-146	412.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	blpY	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NMLHFLOH_01695	457412.RSAG_00498	2.17e-81	241.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,3WKGG@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NMLHFLOH_01696	457412.RSAG_00497	8.25e-218	600.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3WI0G@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_01697	457412.RSAG_00496	0.0	1323.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
NMLHFLOH_01698	457412.RSAG_00495	2.89e-175	489.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3WHTI@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NMLHFLOH_01699	457412.RSAG_00494	3.53e-172	481.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NMLHFLOH_01700	457412.RSAG_00493	1.02e-192	538.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NMLHFLOH_01701	457412.RSAG_00491	4.34e-126	358.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,3WH35@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768,Macro
NMLHFLOH_01702	457412.RSAG_00490	6.85e-132	374.0	COG2755@1|root,COG2755@2|Bacteria,1V18W@1239|Firmicutes,24DIM@186801|Clostridia,3WP3Z@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NMLHFLOH_01703	457412.RSAG_00488	5.95e-202	559.0	2FCDN@1|root,344H7@2|Bacteria,1W31R@1239|Firmicutes,256SW@186801|Clostridia	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01704	457412.RSAG_00487	8.67e-124	353.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WJQH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_01705	457412.RSAG_00486	2.66e-271	741.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24NF4@186801|Clostridia,3WJZP@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NMLHFLOH_01706	457412.RSAG_00485	1.48e-80	238.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia	186801|Clostridia	G	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
NMLHFLOH_01707	457412.RSAG_00484	7.22e-119	340.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3WJXC@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_01708	457412.RSAG_00483	0.0	932.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3WM85@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NMLHFLOH_01709	457412.RSAG_00482	0.0	1001.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NMLHFLOH_01710	457412.RSAG_00481	4.8e-109	314.0	2A2TB@1|root,30R6U@2|Bacteria,1V47K@1239|Firmicutes,24IKY@186801|Clostridia,3WPJ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01711	457412.RSAG_00480	1.53e-47	152.0	2CAM5@1|root,3441D@2|Bacteria,1VZ09@1239|Firmicutes,252SV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01712	457412.RSAG_00479	2.48e-135	384.0	2DPKP@1|root,332J8@2|Bacteria,1VU7P@1239|Firmicutes,24YII@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01713	457412.RSAG_00478	4.6e-113	324.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3WJXC@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_01714	1121115.AXVN01000004_gene2002	6.88e-19	85.1	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01715	457412.RSAG_00997	7.71e-183	509.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WIVB@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
NMLHFLOH_01716	457412.RSAG_00995	4.8e-313	851.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WH66@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
NMLHFLOH_01717	1121115.AXVN01000002_gene1336	3.36e-124	354.0	COG4767@1|root,COG4767@2|Bacteria,1V852@1239|Firmicutes,25BHY@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NMLHFLOH_01718	457412.RSAG_00951	2.35e-206	570.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NMLHFLOH_01719	1121115.AXVN01000002_gene1338	7.62e-86	253.0	2CJZW@1|root,30J0V@2|Bacteria,1UVFN@1239|Firmicutes,2596T@186801|Clostridia,3Y21H@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01720	457412.RSAG_00949	0.0	1214.0	COG1520@1|root,COG1520@2|Bacteria,1TQ7F@1239|Firmicutes,249BV@186801|Clostridia,3WHZZ@541000|Ruminococcaceae	186801|Clostridia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
NMLHFLOH_01721	1121115.AXVN01000002_gene1340	0.0	1092.0	COG0534@1|root,COG0534@2|Bacteria,1V10K@1239|Firmicutes,24CIC@186801|Clostridia	186801|Clostridia	TV	MatE	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MatE
NMLHFLOH_01722	1121115.AXVN01000002_gene1341	0.0	5913.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
NMLHFLOH_01723	1121115.AXVN01000002_gene1342	2.15e-63	194.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NMLHFLOH_01724	1121115.AXVN01000002_gene1343	6.93e-154	432.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,25D1G@186801|Clostridia	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
NMLHFLOH_01725	457412.RSAG_00944	3.4e-258	706.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3WPXI@541000|Ruminococcaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
NMLHFLOH_01726	1121115.AXVN01000002_gene1345	0.0	874.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XYXE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
NMLHFLOH_01727	1121115.AXVN01000002_gene1346	4.29e-228	629.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3XYSH@572511|Blautia	186801|Clostridia	C	Electron transport complex	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NMLHFLOH_01728	1121115.AXVN01000002_gene1347	4.29e-128	365.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NMLHFLOH_01729	457412.RSAG_00940	1.43e-161	453.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3WHAI@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
NMLHFLOH_01730	1121115.AXVN01000002_gene1349	9.51e-122	348.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NMLHFLOH_01731	1121115.AXVN01000002_gene1350	5.72e-195	540.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3XZFG@572511|Blautia	186801|Clostridia	C	F420-non-reducing hydrogenase	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NMLHFLOH_01732	457412.RSAG_00937	9.43e-132	375.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NMLHFLOH_01733	1121115.AXVN01000002_gene1352	3.72e-238	655.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NMLHFLOH_01734	1121115.AXVN01000002_gene1353	2.16e-84	249.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NMLHFLOH_01735	1121115.AXVN01000002_gene1354	0.0	1467.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3XYUZ@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NMLHFLOH_01736	1121115.AXVN01000002_gene1355	1.68e-310	848.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
NMLHFLOH_01737	1121115.AXVN01000002_gene1356	0.0	942.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3XYMX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
NMLHFLOH_01738	1121115.AXVN01000002_gene1357	3.45e-109	313.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NMLHFLOH_01739	1121115.AXVN01000002_gene1358	1.01e-67	205.0	2CSSR@1|root,32SRT@2|Bacteria,1VKAJ@1239|Firmicutes,24UWA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01740	1121115.AXVN01000002_gene1359	5.72e-221	612.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3Y0BT@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
NMLHFLOH_01741	1121115.AXVN01000002_gene1360	2.15e-81	241.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NMLHFLOH_01742	457412.RSAG_00926	6.24e-39	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NMLHFLOH_01743	1121115.AXVN01000002_gene1361	2.47e-77	231.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
NMLHFLOH_01744	457412.RSAG_00924	0.0	1044.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
NMLHFLOH_01745	457412.RSAG_00923	0.0	1317.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NMLHFLOH_01746	1121115.AXVN01000002_gene1364	1.79e-57	188.0	2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01747	457412.RSAG_00921	0.0	1485.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
NMLHFLOH_01748	457412.RSAG_00920	1.73e-248	681.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,24E6T@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NMLHFLOH_01749	457412.RSAG_00919	8.42e-102	295.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
NMLHFLOH_01751	457412.RSAG_00917	4.64e-227	624.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
NMLHFLOH_01752	457412.RSAG_00916	3.92e-214	590.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WSCK@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NMLHFLOH_01753	457412.RSAG_04704	7.53e-189	522.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia,3WIG0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01754	457412.RSAG_00913	6.29e-141	397.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3WK2W@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
NMLHFLOH_01755	457412.RSAG_00912	5.54e-88	258.0	COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,3WHGZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186,DUF5131
NMLHFLOH_01756	457412.RSAG_00911	2.92e-38	127.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia,3WQQT@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
NMLHFLOH_01757	457412.RSAG_00910	0.0	885.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01758	457412.RSAG_00909	3.68e-171	478.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_01759	457412.RSAG_00908	2.17e-214	593.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3WI1Q@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NMLHFLOH_01760	457412.RSAG_00907	1.28e-205	570.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia,3WPNA@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NMLHFLOH_01763	457412.RSAG_00904	0.0	893.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_01764	457412.RSAG_03270	0.0	864.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NMLHFLOH_01765	1121115.AXVN01000135_gene969	0.0	989.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NMLHFLOH_01766	457412.RSAG_03268	3.12e-120	342.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WRVA@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NMLHFLOH_01767	1121115.AXVN01000135_gene972	9.72e-103	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NMLHFLOH_01768	457412.RSAG_03266	5.35e-246	676.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3WGIY@541000|Ruminococcaceae	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NMLHFLOH_01769	457412.RSAG_03265	1.41e-265	727.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NMLHFLOH_01770	457412.RSAG_03264	0.0	1478.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3WHM2@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
NMLHFLOH_01771	457412.RSAG_04579	0.0	1315.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3WHFN@541000|Ruminococcaceae	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01772	457412.RSAG_03261	1.05e-156	440.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NMLHFLOH_01773	1121115.AXVN01000058_gene2553	0.0	1064.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3XZGJ@572511|Blautia	186801|Clostridia	S	Glyco_18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
NMLHFLOH_01774	1121115.AXVN01000058_gene2552	1.72e-40	133.0	2EHIK@1|root,3498W@2|Bacteria,1VYKX@1239|Firmicutes,252YA@186801|Clostridia,3Y0QM@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01775	457412.RSAG_03258	2.2e-171	479.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
NMLHFLOH_01776	1121115.AXVN01000058_gene2550	1.42e-39	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NMLHFLOH_01777	457412.RSAG_03256	1.17e-221	612.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WIJ5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NMLHFLOH_01778	457412.RSAG_03255	9.39e-256	701.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHQZ@541000|Ruminococcaceae	186801|Clostridia	S	transport system permease	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NMLHFLOH_01779	457412.RSAG_03254	0.0	983.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NMLHFLOH_01780	1121115.AXVN01000058_gene2546	1.21e-286	782.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3Y2EG@572511|Blautia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NMLHFLOH_01781	1121115.AXVN01000058_gene2545	3.78e-20	81.6	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NMLHFLOH_01782	457412.RSAG_03250	1.01e-99	290.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24VXI@186801|Clostridia,3WRY4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NMLHFLOH_01783	1121115.AXVN01000058_gene2543	2.12e-310	847.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NMLHFLOH_01784	1121115.AXVN01000058_gene2542	2.09e-95	278.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NMLHFLOH_01785	1121115.AXVN01000058_gene2541	0.0	1300.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NMLHFLOH_01786	1121115.AXVN01000058_gene2540	3.05e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
NMLHFLOH_01787	457412.RSAG_03244	3.43e-101	293.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJ32@541000|Ruminococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
NMLHFLOH_01788	1121115.AXVN01000058_gene2538	1.39e-62	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
NMLHFLOH_01789	1121115.AXVN01000058_gene2537	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
NMLHFLOH_01790	457412.RSAG_03241	6.65e-178	494.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3WGSY@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NMLHFLOH_01791	1121115.AXVN01000058_gene2535	7.12e-199	550.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NMLHFLOH_01792	457412.RSAG_03239	0.0	999.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NMLHFLOH_01793	1121115.AXVN01000039_gene3304	1.22e-312	850.0	COG3864@1|root,COG3864@2|Bacteria,1VS2U@1239|Firmicutes,24ZZ3@186801|Clostridia,3XZT4@572511|Blautia	186801|Clostridia	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NMLHFLOH_01794	1121115.AXVN01000039_gene3303	8.7e-65	198.0	2F5U3@1|root,33YD0@2|Bacteria,1VVXV@1239|Firmicutes,250VV@186801|Clostridia,3Y21G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01795	457412.RSAG_03236	0.0	1115.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_01796	1121115.AXVN01000039_gene3301	7.24e-304	827.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XYJB@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NMLHFLOH_01797	1121115.AXVN01000039_gene3300	5.53e-303	830.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	xanP	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
NMLHFLOH_01798	457412.RSAG_03233	0.0	1155.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3WI3C@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NMLHFLOH_01799	457412.RSAG_03232	1.3e-194	538.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3WSCN@541000|Ruminococcaceae	186801|Clostridia	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NMLHFLOH_01800	1121115.AXVN01000039_gene3297	2.01e-207	572.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NMLHFLOH_01801	457412.RSAG_03230	1.88e-191	533.0	COG3247@1|root,COG3247@2|Bacteria,1VAQW@1239|Firmicutes,24QIF@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NMLHFLOH_01802	457412.RSAG_03229	3.73e-185	515.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NMLHFLOH_01803	457412.RSAG_03228	1.41e-120	344.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24NJ3@186801|Clostridia,3WMNS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NMLHFLOH_01804	457412.RSAG_03227	0.0	905.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
NMLHFLOH_01805	457412.RSAG_03226	4.91e-284	776.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
NMLHFLOH_01806	1121115.AXVN01000039_gene3291	4.31e-172	481.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_01807	1121115.AXVN01000039_gene3290	8.12e-48	152.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01808	1121115.AXVN01000039_gene3289	1.01e-139	394.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NMLHFLOH_01809	742765.HMPREF9457_02430	1.18e-295	806.0	2CIG8@1|root,2Z7UI@2|Bacteria,1TRB9@1239|Firmicutes,24CHU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01810	1121115.AXVN01000039_gene3287	4.16e-125	356.0	28J10@1|root,2Z8Y3@2|Bacteria,1UYTH@1239|Firmicutes,24FAW@186801|Clostridia,3XZRK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01814	457412.RSAG_00140	0.0	1069.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3WGFA@541000|Ruminococcaceae	186801|Clostridia	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NMLHFLOH_01815	457412.RSAG_00141	1.58e-284	777.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3WHRI@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NMLHFLOH_01816	1121115.AXVN01000020_gene85	1.27e-311	848.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3XZKZ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
NMLHFLOH_01817	457412.RSAG_00143	4.61e-222	612.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NMLHFLOH_01818	457412.RSAG_00144	0.0	1318.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NMLHFLOH_01819	457412.RSAG_00145	0.0	1711.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NMLHFLOH_01820	457412.RSAG_00147	1.79e-121	346.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NMLHFLOH_01821	457412.RSAG_00148	8.36e-296	807.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,3WGCD@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
NMLHFLOH_01822	457412.RSAG_00149	4.62e-255	702.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJIU@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_01823	457412.RSAG_00150	9.1e-163	455.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia,3WNIU@541000|Ruminococcaceae	186801|Clostridia	L	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
NMLHFLOH_01824	457412.RSAG_00151	0.0	2010.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3WMH8@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
NMLHFLOH_01825	457412.RSAG_00152	1.78e-73	220.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01826	457412.RSAG_04723	7.21e-143	403.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
NMLHFLOH_01827	457412.RSAG_00154	1.41e-154	433.0	COG2206@1|root,COG2206@2|Bacteria,1UKHX@1239|Firmicutes,25FXF@186801|Clostridia,3WP2X@541000|Ruminococcaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01828	457412.RSAG_04724	5.34e-72	217.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia,3WMHH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01829	457412.RSAG_04725	3.67e-126	359.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia,3WRUA@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_01830	457412.RSAG_00157	1.27e-249	685.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3WH29@541000|Ruminococcaceae	186801|Clostridia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NMLHFLOH_01831	1121115.AXVN01000032_gene402	0.0	1641.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NMLHFLOH_01832	457412.RSAG_00159	1.36e-66	202.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NMLHFLOH_01833	1121115.AXVN01000032_gene400	2.73e-303	828.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZGF@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_01834	457412.RSAG_00161	0.0	928.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NMLHFLOH_01835	1121115.AXVN01000032_gene398	2.89e-222	612.0	COG2866@1|root,COG2866@2|Bacteria,1UEH5@1239|Firmicutes,25JE5@186801|Clostridia,3Y01R@572511|Blautia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
NMLHFLOH_01836	1121115.AXVN01000032_gene397	1.1e-311	871.0	2DUK2@1|root,33R10@2|Bacteria,1VR47@1239|Firmicutes,24Z5G@186801|Clostridia,3Y0TJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01837	457412.RSAG_00164	1.97e-295	806.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3WH60@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NMLHFLOH_01838	1121115.AXVN01000032_gene395	1.28e-132	375.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,3XZW4@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
NMLHFLOH_01839	1121115.AXVN01000032_gene394	2.05e-42	139.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
NMLHFLOH_01840	457412.RSAG_00167	1.43e-190	530.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NMLHFLOH_01841	457412.RSAG_00169	2.36e-111	320.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NMLHFLOH_01842	1121115.AXVN01000032_gene391	7.09e-228	629.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3XYTC@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NMLHFLOH_01843	457412.RSAG_00172	4.19e-283	773.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3WJNK@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NMLHFLOH_01844	1121115.AXVN01000032_gene389	2.8e-63	193.0	2DVZX@1|root,33XWD@2|Bacteria,1U4E1@1239|Firmicutes,24VHN@186801|Clostridia,3Y0V7@572511|Blautia	186801|Clostridia	S	COG NOG13846 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	YabP
NMLHFLOH_01845	1121115.AXVN01000032_gene388	7.11e-132	374.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NMLHFLOH_01846	1121115.AXVN01000032_gene387	1.05e-107	310.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3XZU3@572511|Blautia	186801|Clostridia	H	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NMLHFLOH_01847	1121115.AXVN01000032_gene386	9.42e-258	707.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia,3XZZR@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
NMLHFLOH_01848	1121115.AXVN01000032_gene385	0.0	1665.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NMLHFLOH_01849	457412.RSAG_00178	2.23e-202	561.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NMLHFLOH_01850	457412.RSAG_00179	3.4e-200	556.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3WJ77@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
NMLHFLOH_01851	457412.RSAG_00180	4.89e-264	722.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3WH61@541000|Ruminococcaceae	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NMLHFLOH_01852	1121115.AXVN01000032_gene381	0.0	973.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
NMLHFLOH_01853	457412.RSAG_00183	4.31e-193	536.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
NMLHFLOH_01854	1121115.AXVN01000032_gene379	0.0	1689.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3XZ0I@572511|Blautia	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
NMLHFLOH_01855	1121115.AXVN01000032_gene378	4.47e-187	518.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NMLHFLOH_01856	1121115.AXVN01000032_gene377	0.0	905.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NMLHFLOH_01857	457412.RSAG_02418	0.0	2185.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NMLHFLOH_01858	1121115.AXVN01000015_gene3729	2.4e-65	199.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NMLHFLOH_01859	1121115.AXVN01000015_gene3728	2.32e-172	481.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3XYKS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NMLHFLOH_01860	457412.RSAG_02415	1.3e-264	726.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,3WGFE@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	xylH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
NMLHFLOH_01861	1121115.AXVN01000015_gene3726	0.0	988.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3Y18A@572511|Blautia	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
NMLHFLOH_01862	1121115.AXVN01000015_gene3725	2.8e-255	700.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
NMLHFLOH_01863	1121115.AXVN01000015_gene3724	6.93e-261	715.0	COG4213@1|root,COG4213@2|Bacteria,1UNTA@1239|Firmicutes	1239|Firmicutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NMLHFLOH_01864	1121115.AXVN01000015_gene3723	0.0	1038.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_01865	1121115.AXVN01000015_gene3722	0.0	930.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3Y15R@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NMLHFLOH_01866	1121115.AXVN01000015_gene3721	1.57e-237	654.0	COG1879@1|root,COG1879@2|Bacteria,1V3FA@1239|Firmicutes,24G5Q@186801|Clostridia,3Y1NU@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NMLHFLOH_01867	1121115.AXVN01000015_gene3720	4.89e-164	460.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NMLHFLOH_01868	457412.RSAG_02406	4.37e-151	426.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NMLHFLOH_01869	1121115.AXVN01000015_gene3718	1.09e-226	624.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
NMLHFLOH_01870	1121115.AXVN01000015_gene3717	2.95e-117	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
NMLHFLOH_01871	457412.RSAG_02403	1.68e-310	847.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NMLHFLOH_01872	457412.RSAG_02402	3.19e-146	412.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,3WITW@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_01873	1121115.AXVN01000015_gene3708	2.38e-160	450.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3XZDH@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
NMLHFLOH_01874	1121115.AXVN01000015_gene3707	8.69e-180	500.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3XZSC@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
NMLHFLOH_01875	1121115.AXVN01000015_gene3706	4.88e-232	641.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3XYTB@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NMLHFLOH_01876	1121115.AXVN01000015_gene3705	3.6e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3XYQM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
NMLHFLOH_01877	1121115.AXVN01000015_gene3704	3.62e-268	735.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3XZ26@572511|Blautia	186801|Clostridia	E	COG COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
NMLHFLOH_01878	457412.RSAG_02398	8.04e-72	216.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3WIYY@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NMLHFLOH_01879	457412.RSAG_02397	6.11e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WMNQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NMLHFLOH_01880	1121115.AXVN01000015_gene3701	1.08e-107	311.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NMLHFLOH_01881	1121115.AXVN01000016_gene3645	1.19e-71	215.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
NMLHFLOH_01882	457412.RSAG_02394	4.37e-266	731.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NMLHFLOH_01883	457412.RSAG_02393	1.37e-204	573.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3WMQV@541000|Ruminococcaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
NMLHFLOH_01884	457412.RSAG_02392	7.99e-312	849.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NMLHFLOH_01885	457412.RSAG_02391	6.82e-252	692.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NMLHFLOH_01886	1121115.AXVN01000016_gene3650	0.0	897.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3XYZG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NMLHFLOH_01887	1121115.AXVN01000016_gene3651	9.56e-217	599.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NMLHFLOH_01888	457412.RSAG_02388	0.0	1169.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NMLHFLOH_01889	457412.RSAG_02387	0.0	1377.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WI1C@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein dimerisation domain	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
NMLHFLOH_01890	1121115.AXVN01000016_gene3654	1.11e-125	358.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NMLHFLOH_01891	1121115.AXVN01000016_gene3655	1.27e-222	613.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NMLHFLOH_01892	457412.RSAG_02384	2.79e-102	295.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
NMLHFLOH_01893	1121115.AXVN01000016_gene3657	1.03e-239	659.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3XYMQ@572511|Blautia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NMLHFLOH_01894	1121115.AXVN01000016_gene3658	5.7e-260	712.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NMLHFLOH_01895	1121115.AXVN01000016_gene3659	1.08e-144	407.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia,3Y0IX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01896	1121115.AXVN01000016_gene3660	0.0	1575.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_01897	1121115.AXVN01000016_gene3661	0.0	1867.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_01898	1121115.AXVN01000016_gene3662	3.06e-288	790.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia,3XZ44@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_01899	1121115.AXVN01000016_gene3663	1.9e-165	462.0	COG3279@1|root,COG3279@2|Bacteria,1UHWR@1239|Firmicutes,25BYP@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_01901	457412.RSAG_03327	1.33e-187	521.0	292MS@1|root,2ZQ5N@2|Bacteria,1VRQ1@1239|Firmicutes,24ZSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01902	1121115.AXVN01000021_gene1680	3.81e-224	617.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
NMLHFLOH_01903	1121115.AXVN01000021_gene1681	2.28e-308	840.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NMLHFLOH_01904	1121115.AXVN01000021_gene1682	1.11e-113	327.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
NMLHFLOH_01905	1121115.AXVN01000021_gene1683	1.77e-215	597.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NMLHFLOH_01906	1121115.AXVN01000021_gene1684	1.32e-176	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NMLHFLOH_01907	1121115.AXVN01000021_gene1685	1.76e-232	639.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NMLHFLOH_01908	1121115.AXVN01000021_gene1686	1.27e-310	862.0	2DN2J@1|root,32V6S@2|Bacteria,1V1QE@1239|Firmicutes,25HR2@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NMLHFLOH_01909	457412.RSAG_03319	0.0	944.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3WIU9@541000|Ruminococcaceae	186801|Clostridia	N	transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
NMLHFLOH_01910	1121115.AXVN01000021_gene1688	1.03e-184	516.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
NMLHFLOH_01911	457412.RSAG_03317	7.9e-247	679.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_01912	457412.RSAG_03316	9.77e-171	476.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
NMLHFLOH_01913	1121115.AXVN01000021_gene1691	0.0	1219.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NMLHFLOH_01914	457412.RSAG_03314	0.0	877.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3WGHG@541000|Ruminococcaceae	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NMLHFLOH_01915	1121115.AXVN01000021_gene1693	7.4e-188	526.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3XZCW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NMLHFLOH_01916	457412.RSAG_03312	7.58e-287	786.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NMLHFLOH_01917	457412.RSAG_03311	1.52e-47	151.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NMLHFLOH_01918	457412.RSAG_03310	6.74e-80	237.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NMLHFLOH_01919	457412.RSAG_03309	1.37e-21	84.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NMLHFLOH_01920	1121115.AXVN01000021_gene1696	0.0	889.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NMLHFLOH_01921	457412.RSAG_03307	4.51e-260	713.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NMLHFLOH_01922	1121115.AXVN01000021_gene1698	4.45e-42	137.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NMLHFLOH_01923	1121115.AXVN01000021_gene1699	2.51e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NMLHFLOH_01924	457412.RSAG_03304	0.0	1450.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3WGDF@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NMLHFLOH_01925	1121115.AXVN01000021_gene1701	3.77e-217	599.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NMLHFLOH_01926	1121115.AXVN01000021_gene1702	3.05e-89	263.0	2EY21@1|root,33RAZ@2|Bacteria,1VSPZ@1239|Firmicutes,24YUD@186801|Clostridia,3Y1ZI@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NMLHFLOH_01927	1121115.AXVN01000021_gene1703	9.78e-156	437.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NMLHFLOH_01928	1121115.AXVN01000021_gene1704	1.14e-200	557.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NMLHFLOH_01929	457412.RSAG_03299	0.0	1090.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
NMLHFLOH_01930	457412.RSAG_03298	9.98e-140	394.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NMLHFLOH_01931	1121115.AXVN01000021_gene1707	6.42e-112	322.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NMLHFLOH_01932	1121115.AXVN01000021_gene1708	1.35e-300	821.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NMLHFLOH_01933	1121115.AXVN01000021_gene1709	1.25e-284	777.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NMLHFLOH_01934	1121115.AXVN01000021_gene1710	4.04e-266	729.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_01935	1121115.AXVN01000021_gene1711	2.92e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_01936	1121115.AXVN01000021_gene1712	0.0	956.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA_1	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NMLHFLOH_01937	1121115.AXVN01000021_gene1713	6.51e-140	395.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NMLHFLOH_01938	457412.RSAG_03291	1.15e-234	645.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WI7S@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NMLHFLOH_01939	457412.RSAG_03290	4.87e-205	568.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3WHA4@541000|Ruminococcaceae	186801|Clostridia	S	PSP1 C-terminal domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NMLHFLOH_01940	1121115.AXVN01000021_gene1716	6.13e-177	493.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NMLHFLOH_01941	1121115.AXVN01000021_gene1717	8.4e-198	548.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NMLHFLOH_01942	1121115.AXVN01000021_gene1718	0.0	1269.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NMLHFLOH_01943	457412.RSAG_03286	0.0	1596.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3WGW0@541000|Ruminococcaceae	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NMLHFLOH_01944	1121115.AXVN01000021_gene1720	4.28e-131	372.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01945	457412.RSAG_03284	1.9e-171	478.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3WIQF@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NMLHFLOH_01947	457412.RSAG_03106	8.12e-91	265.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NMLHFLOH_01948	457412.RSAG_03104	2.6e-111	319.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,3WJ4Z@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NMLHFLOH_01949	457412.RSAG_03103	0.0	995.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,24EGZ@186801|Clostridia,3WI6H@541000|Ruminococcaceae	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
NMLHFLOH_01950	457412.RSAG_03102	3.87e-169	471.0	COG2819@1|root,COG2819@2|Bacteria,1TR41@1239|Firmicutes,24EH0@186801|Clostridia,3WS55@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NMLHFLOH_01951	457412.RSAG_03101	3.04e-36	122.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HTH_34,HxlR
NMLHFLOH_01952	457412.RSAG_03100	5.23e-107	308.0	2DBT4@1|root,2ZAVD@2|Bacteria,1V0AF@1239|Firmicutes,24DH6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
NMLHFLOH_01953	457412.RSAG_03098	7.06e-81	239.0	COG2337@1|root,COG2337@2|Bacteria,1TTJP@1239|Firmicutes,25MHP@186801|Clostridia,3WQFT@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NMLHFLOH_01955	457412.RSAG_03096	0.0	1059.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_01956	457412.RSAG_03095	0.0	1111.0	COG1961@1|root,COG1961@2|Bacteria,1V29C@1239|Firmicutes,24GBE@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_01957	457412.RSAG_03094	0.0	1051.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3WGJ0@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_01958	1121115.AXVN01000073_gene2008	5.2e-181	511.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYIB@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NMLHFLOH_01959	457412.RSAG_03091	1.02e-42	140.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Y@186801|Clostridia,3WM7P@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
NMLHFLOH_01960	457412.RSAG_03090	0.0	1460.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NMLHFLOH_01961	457412.RSAG_03089	1.34e-104	302.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NMLHFLOH_01962	457412.RSAG_03088	1.59e-136	386.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WI5H@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_01963	1121115.AXVN01000073_gene2013	5.74e-175	497.0	2EY3W@1|root,33RCQ@2|Bacteria,1VU3P@1239|Firmicutes,24XPJ@186801|Clostridia,3XZZ1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01964	1121115.AXVN01000073_gene2014	1.62e-160	450.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NMLHFLOH_01965	1121115.AXVN01000073_gene2015	1.12e-116	335.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NMLHFLOH_01966	1121115.AXVN01000073_gene2016	1.9e-170	475.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NMLHFLOH_01967	1121115.AXVN01000073_gene2017	9.99e-176	491.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3XZGP@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NMLHFLOH_01968	457412.RSAG_03082	9.65e-271	741.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NMLHFLOH_01969	457412.RSAG_03081	1.07e-302	826.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NMLHFLOH_01970	1121115.AXVN01000073_gene2020	0.0	956.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,3Y2A9@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
NMLHFLOH_01971	457412.RSAG_03080	5.38e-165	462.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,3WSCZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
NMLHFLOH_01972	457412.RSAG_03079	7.65e-154	433.0	2EX9H@1|root,33QK7@2|Bacteria,1VRP0@1239|Firmicutes,24YQ9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01973	1121115.AXVN01000073_gene2023	0.0	1132.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NMLHFLOH_01974	1469948.JPNB01000001_gene878	4.45e-29	113.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,36GMJ@31979|Clostridiaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
NMLHFLOH_01975	1121115.AXVN01000073_gene2025	1.22e-308	840.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3XZDX@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NMLHFLOH_01977	1121115.AXVN01000005_gene2204	3.45e-239	657.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3XYN7@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NMLHFLOH_01978	1121115.AXVN01000005_gene2205	0.0	1176.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
NMLHFLOH_01979	1121115.AXVN01000005_gene2206	2.44e-234	649.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NMLHFLOH_01980	1121115.AXVN01000005_gene2207	1.23e-166	466.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NMLHFLOH_01981	457412.RSAG_03071	5.46e-187	519.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NMLHFLOH_01982	457412.RSAG_03070	0.0	1103.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
NMLHFLOH_01984	1121115.AXVN01000005_gene2210	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NMLHFLOH_01985	457412.RSAG_03068	2.36e-216	597.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NMLHFLOH_01986	1121115.AXVN01000005_gene2212	1.89e-95	277.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NMLHFLOH_01987	457412.RSAG_03066	5.78e-305	832.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NMLHFLOH_01988	457412.RSAG_03065	1.42e-270	740.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NMLHFLOH_01989	457412.RSAG_03064	0.0	877.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NMLHFLOH_01990	457412.RSAG_03063	0.0	992.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3WI8N@541000|Ruminococcaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NMLHFLOH_01991	457412.RSAG_03062	0.0	1422.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NMLHFLOH_01992	1121115.AXVN01000119_gene3269	2.28e-121	347.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NMLHFLOH_01993	1121115.AXVN01000119_gene3268	0.0	949.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NMLHFLOH_01994	1121115.AXVN01000119_gene3267	2.43e-144	407.0	COG1247@1|root,COG1247@2|Bacteria,1UKI4@1239|Firmicutes,25FXM@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_01995	1121115.AXVN01000136_gene975	2.87e-289	790.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NMLHFLOH_01996	457421.CBFG_01963	1.54e-14	70.1	2DXIG@1|root,3455C@2|Bacteria,1VYKU@1239|Firmicutes,2542Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01997	457412.RSAG_01794	2.64e-124	353.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3WJDN@541000|Ruminococcaceae	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NMLHFLOH_01998	457412.RSAG_01793	1.46e-96	280.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3WKJ0@541000|Ruminococcaceae	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_01999	1121115.AXVN01000136_gene978	9.22e-210	578.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3XZ5E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02000	1121115.AXVN01000136_gene979	1.02e-146	414.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3XZTD@572511|Blautia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
NMLHFLOH_02001	1121115.AXVN01000136_gene980	2.43e-240	660.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
NMLHFLOH_02002	1121115.AXVN01000136_gene981	3.6e-257	716.0	COG5263@1|root,COG5263@2|Bacteria,1UK2Z@1239|Firmicutes,24XW0@186801|Clostridia,3XZWP@572511|Blautia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NMLHFLOH_02003	1121115.AXVN01000126_gene3812	4.56e-205	583.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3XZ4Y@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NMLHFLOH_02004	1121115.AXVN01000126_gene3813	2.46e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,3Y27X@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NMLHFLOH_02005	1121115.AXVN01000126_gene3814	9.74e-98	284.0	COG4810@1|root,COG4810@2|Bacteria,1V5A1@1239|Firmicutes,24IPC@186801|Clostridia,3Y03M@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NMLHFLOH_02006	457412.RSAG_01785	3.45e-121	345.0	COG4917@1|root,COG4917@2|Bacteria,1V54Y@1239|Firmicutes,25DMI@186801|Clostridia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NMLHFLOH_02007	1121115.AXVN01000126_gene3816	3.86e-74	221.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
NMLHFLOH_02008	457412.RSAG_01783	0.0	1495.0	COG4733@1|root,COG4870@1|root,COG4733@2|Bacteria,COG4870@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia,3WRJP@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
NMLHFLOH_02009	1121115.AXVN01000126_gene3818	7.07e-178	502.0	COG3266@1|root,COG3266@2|Bacteria,1VS06@1239|Firmicutes,24YEU@186801|Clostridia,3Y1K6@572511|Blautia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02010	1121115.AXVN01000086_gene3999	4.49e-89	261.0	2EYFK@1|root,33RPH@2|Bacteria,1VT8U@1239|Firmicutes,24XWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02011	457412.RSAG_01780	0.0	1698.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NMLHFLOH_02012	457412.RSAG_01779	1.4e-195	541.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3WIZP@541000|Ruminococcaceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NMLHFLOH_02013	457412.RSAG_01778	5.57e-214	590.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae	186801|Clostridia	G	L-fuculose phosphate aldolase	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NMLHFLOH_02014	1121115.AXVN01000086_gene4003	0.0	910.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia	186801|Clostridia	C	Aldehyde dehydrogenase family	eutE	-	1.2.1.10,1.2.1.87	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00228,R01172,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
NMLHFLOH_02015	457412.RSAG_01776	6.67e-303	825.0	COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae	186801|Clostridia	C	Glucose dehydrogenase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NMLHFLOH_02016	1121115.AXVN01000086_gene4005	2.19e-67	204.0	2CTB7@1|root,32ST1@2|Bacteria,1UPS8@1239|Firmicutes,25HN2@186801|Clostridia	186801|Clostridia	S	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_02017	1121115.AXVN01000086_gene4006	7.33e-51	161.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_02018	1121115.AXVN01000086_gene4007	1.77e-62	191.0	COG4577@1|root,COG4577@2|Bacteria,1V9YU@1239|Firmicutes,24MUN@186801|Clostridia,3Y0DW@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_02019	1121115.AXVN01000086_gene4008	1.22e-69	214.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_02020	457412.RSAG_01771	2.7e-146	412.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
NMLHFLOH_02021	1121115.AXVN01000086_gene4010	9.07e-52	164.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
NMLHFLOH_02022	1121115.AXVN01000086_gene4011	0.0	869.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
NMLHFLOH_02023	1121115.AXVN01000086_gene4012	6.28e-118	338.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,3XZUS@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
NMLHFLOH_02024	1121115.AXVN01000086_gene4013	3.65e-173	484.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3XZ48@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NMLHFLOH_02025	1121115.AXVN01000086_gene4014	2.2e-273	748.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NMLHFLOH_02026	457412.RSAG_01765	2.78e-221	614.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,3WPYX@541000|Ruminococcaceae	186801|Clostridia	S	Haem-degrading	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
NMLHFLOH_02027	1121115.AXVN01000086_gene4016	7.31e-212	584.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V1UE@1239|Firmicutes,24AK4@186801|Clostridia,3XZ87@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NMLHFLOH_02028	457412.RSAG_01763	0.0	1233.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3WHBE@541000|Ruminococcaceae	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
NMLHFLOH_02029	457412.RSAG_03510	2.27e-103	298.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3WJ3H@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
NMLHFLOH_02030	457412.RSAG_01762	0.0	1038.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WJ5A@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NMLHFLOH_02031	1121115.AXVN01000081_gene3045	0.0	1143.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NMLHFLOH_02032	1121115.AXVN01000081_gene3046	1.67e-225	622.0	COG1879@1|root,COG1879@2|Bacteria,1TPWA@1239|Firmicutes,25PX0@186801|Clostridia,3XYI7@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NMLHFLOH_02033	457412.RSAG_01759	2.59e-229	632.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WNJT@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NMLHFLOH_02034	1121115.AXVN01000081_gene3048	0.0	973.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
NMLHFLOH_02035	1121115.AXVN01000081_gene3049	2.02e-222	614.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3XZJF@572511|Blautia	186801|Clostridia	P	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NMLHFLOH_02036	457412.RSAG_03022	7.09e-258	710.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,248DM@186801|Clostridia,3WGJU@541000|Ruminococcaceae	186801|Clostridia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
NMLHFLOH_02037	457412.RSAG_03021	2.93e-177	493.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3WNN6@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
NMLHFLOH_02038	457412.RSAG_03020	1.25e-241	664.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,3WMXD@541000|Ruminococcaceae	186801|Clostridia	E	Pfam:AHS2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
NMLHFLOH_02039	457412.RSAG_03019	1.17e-95	279.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3WJAY@541000|Ruminococcaceae	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
NMLHFLOH_02040	457412.RSAG_03018	5.45e-312	851.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3WHD3@541000|Ruminococcaceae	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NMLHFLOH_02041	457412.RSAG_03017	6.85e-179	498.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,3WNF8@541000|Ruminococcaceae	186801|Clostridia	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
NMLHFLOH_02042	1121115.AXVN01000005_gene2253	3.67e-149	419.0	COG1102@1|root,COG1102@2|Bacteria,1V5TS@1239|Firmicutes,24HRW@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NMLHFLOH_02043	457412.RSAG_03014	4.02e-237	652.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
NMLHFLOH_02044	457412.RSAG_03013	0.0	1212.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WN2E@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
NMLHFLOH_02045	457412.RSAG_03012	7.46e-232	637.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3WGZV@541000|Ruminococcaceae	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NMLHFLOH_02046	457412.RSAG_03011	6.91e-263	718.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NMLHFLOH_02047	457412.RSAG_03010	3.65e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3WGQ3@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NMLHFLOH_02048	1121115.AXVN01000005_gene2259	1.02e-291	796.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
NMLHFLOH_02049	1121115.AXVN01000005_gene2260	1.71e-190	527.0	COG1278@1|root,COG1278@2|Bacteria,1URQI@1239|Firmicutes,259M3@186801|Clostridia,3Y0QB@572511|Blautia	186801|Clostridia	K	Domain of unknown function (DUF3825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3825
NMLHFLOH_02050	457412.RSAG_03006	3.38e-253	693.0	COG1835@1|root,COG1835@2|Bacteria,1VIE2@1239|Firmicutes,24SHJ@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NMLHFLOH_02051	1121115.AXVN01000005_gene2262	1.53e-161	454.0	2DPYM@1|root,333Z5@2|Bacteria,1VFMY@1239|Firmicutes,24SP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02052	457412.RSAG_03004	6.46e-302	825.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3WGJC@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02053	457412.RSAG_03003	0.0	1046.0	29WVX@1|root,30IHI@2|Bacteria,1UPZS@1239|Firmicutes,257M6@186801|Clostridia,3WIT7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02054	457412.RSAG_03002	6.91e-299	815.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3WH3A@541000|Ruminococcaceae	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NMLHFLOH_02055	1121115.AXVN01000005_gene2266	2.45e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NMLHFLOH_02056	457412.RSAG_03000	1.9e-180	502.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WIAB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NMLHFLOH_02057	457412.RSAG_02999	1.69e-234	646.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NMLHFLOH_02058	457412.RSAG_02998	4.85e-136	386.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3WH5G@541000|Ruminococcaceae	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NMLHFLOH_02059	1121115.AXVN01000005_gene2270	2.12e-222	612.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NMLHFLOH_02060	457412.RSAG_02996	9.54e-153	428.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3WGWP@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
NMLHFLOH_02061	1121115.AXVN01000005_gene2272	0.0	911.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NMLHFLOH_02062	1121115.AXVN01000005_gene2273	1.58e-264	724.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NMLHFLOH_02063	1121115.AXVN01000005_gene2274	8e-49	155.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3Y0TN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NMLHFLOH_02064	1121115.AXVN01000005_gene2275	2.65e-249	684.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NMLHFLOH_02065	1121115.AXVN01000005_gene2276	5.22e-176	491.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
NMLHFLOH_02066	457412.RSAG_02990	0.0	1402.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NMLHFLOH_02067	457412.RSAG_02989	2.34e-140	398.0	COG1207@1|root,COG1207@2|Bacteria,1UHDT@1239|Firmicutes,25Q4M@186801|Clostridia,3WH51@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NMLHFLOH_02068	1121115.AXVN01000005_gene2279	2.42e-183	509.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3Y013@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NMLHFLOH_02069	1121115.AXVN01000005_gene2280	6.9e-166	463.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
NMLHFLOH_02070	1121115.AXVN01000005_gene2281	7.85e-241	662.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
NMLHFLOH_02071	665950.HMPREF1025_01927	1.65e-215	604.0	COG0582@1|root,COG0582@2|Bacteria,1TSN5@1239|Firmicutes,248E3@186801|Clostridia,27M3X@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase,zinc_ribbon_2
NMLHFLOH_02072	411460.RUMTOR_02456	1.31e-38	131.0	COG3464@1|root,COG3464@2|Bacteria,1UK3S@1239|Firmicutes,25FIJ@186801|Clostridia	186801|Clostridia	L	COG NOG23522 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02073	742733.HMPREF9469_05094	1.24e-43	142.0	2DRI9@1|root,33BWS@2|Bacteria,1VKIC@1239|Firmicutes,24V1I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02074	411460.RUMTOR_02009	8.87e-60	187.0	2CUTW@1|root,32SW4@2|Bacteria,1VAWF@1239|Firmicutes,24QFC@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02080	411470.RUMGNA_01356	2.11e-31	125.0	2CJ0P@1|root,2ZE6N@2|Bacteria,1V3F7@1239|Firmicutes,24H04@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02085	428125.CLOLEP_01353	8.78e-61	189.0	2BZ9S@1|root,32R4K@2|Bacteria,1V9IB@1239|Firmicutes,24KN5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02089	1121115.AXVN01000035_gene3859	8.5e-91	266.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3XZ52@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NMLHFLOH_02090	1121115.AXVN01000035_gene3858	3.41e-37	125.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	XK27_05700	-	-	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134	-	-	FtsX
NMLHFLOH_02091	1121115.AXVN01000035_gene3857	5.07e-173	485.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,3Y0E5@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NMLHFLOH_02092	1121115.AXVN01000035_gene3856	9.3e-101	296.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia,3Y0AR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NMLHFLOH_02093	1121115.AXVN01000035_gene3855	8.2e-68	205.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,25CR8@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NMLHFLOH_02094	1121115.AXVN01000035_gene3854	2.81e-73	221.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
NMLHFLOH_02095	1121115.AXVN01000035_gene3853	4.58e-215	593.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia,3Y1BG@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_02096	1121115.AXVN01000035_gene3852	7.17e-280	768.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,3XZZY@572511|Blautia	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
NMLHFLOH_02097	457412.RSAG_02928	1.01e-223	615.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WGE0@541000|Ruminococcaceae	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
NMLHFLOH_02098	1121115.AXVN01000035_gene3850	7.83e-153	429.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,3Y19V@572511|Blautia	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NMLHFLOH_02099	457412.RSAG_02930	0.0	1745.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSS0@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
NMLHFLOH_02100	1121115.AXVN01000035_gene3848	0.0	1274.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3XZAR@572511|Blautia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NMLHFLOH_02101	1121115.AXVN01000035_gene3847	3.16e-236	651.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NMLHFLOH_02102	1121115.AXVN01000035_gene3846	8.91e-136	386.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NMLHFLOH_02103	1121115.AXVN01000035_gene3845	0.0	1172.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NMLHFLOH_02104	1121115.AXVN01000035_gene3844	5.15e-269	738.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3XYJ6@572511|Blautia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NMLHFLOH_02105	457412.RSAG_02936	2.15e-177	493.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,3WJNZ@541000|Ruminococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
NMLHFLOH_02106	1121115.AXVN01000035_gene3842	2.47e-223	616.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NMLHFLOH_02107	457412.RSAG_02938	7.68e-172	480.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NMLHFLOH_02108	1121115.AXVN01000035_gene3840	1.75e-275	753.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XYUM@572511|Blautia	186801|Clostridia	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NMLHFLOH_02109	457412.RSAG_02940	7.55e-286	780.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3WGMK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
NMLHFLOH_02110	1121115.AXVN01000035_gene3838	2.29e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3Y0BS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NMLHFLOH_02111	457412.RSAG_02942	0.0	870.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
NMLHFLOH_02112	1121115.AXVN01000035_gene3836	2.28e-58	180.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
NMLHFLOH_02113	457412.RSAG_02944	9.05e-93	271.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
NMLHFLOH_02114	1121115.AXVN01000035_gene3834	4.26e-45	146.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NMLHFLOH_02115	457412.RSAG_02946	0.0	1224.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NMLHFLOH_02116	1121115.AXVN01000035_gene3832	6.22e-74	221.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NMLHFLOH_02117	1121115.AXVN01000035_gene3831	1.86e-89	262.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NMLHFLOH_02118	457412.RSAG_02949	2.41e-149	420.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3WI82@541000|Ruminococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
NMLHFLOH_02119	1121115.AXVN01000035_gene3829	4.02e-304	828.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NMLHFLOH_02120	457412.RSAG_02951	5.91e-143	404.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NMLHFLOH_02121	1280696.ATVY01000009_gene3086	1.24e-252	702.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,25ED1@186801|Clostridia,4BXH2@830|Butyrivibrio	186801|Clostridia	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
NMLHFLOH_02122	457412.RSAG_02953	8.04e-150	422.0	COG1418@1|root,COG1418@2|Bacteria,1UI0F@1239|Firmicutes,24GIY@186801|Clostridia,3WSS1@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
NMLHFLOH_02123	1121115.AXVN01000035_gene3825	1.55e-231	637.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3XZ2T@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NMLHFLOH_02125	457412.RSAG_02955	1.46e-247	681.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WIF6@541000|Ruminococcaceae	186801|Clostridia	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
NMLHFLOH_02126	1121115.AXVN01000035_gene3823	1.64e-166	467.0	COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,24AY1@186801|Clostridia,3Y1HG@572511|Blautia	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
NMLHFLOH_02127	457412.RSAG_02966	0.0	865.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02128	457412.RSAG_02967	2.74e-96	280.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NMLHFLOH_02129	1121115.AXVN01000026_gene1014	1.45e-43	145.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3Y18S@572511|Blautia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_02130	457412.RSAG_02969	1.09e-198	552.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJ00@541000|Ruminococcaceae	186801|Clostridia	L	transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_02131	1280671.AUJH01000028_gene895	8.74e-41	137.0	2CU1H@1|root,32SUI@2|Bacteria,1VB8S@1239|Firmicutes,24PZC@186801|Clostridia,4C0G3@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02132	742765.HMPREF9457_01634	5.05e-216	599.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27X9E@189330|Dorea	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NMLHFLOH_02133	1121115.AXVN01000004_gene1962	8.43e-61	187.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NMLHFLOH_02134	457412.RSAG_00395	2.96e-91	267.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,3WKBK@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
NMLHFLOH_02135	1121115.AXVN01000004_gene1960	9.72e-266	733.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
NMLHFLOH_02136	457412.RSAG_00393	9.23e-270	737.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02137	1121115.AXVN01000004_gene1958	1.93e-181	507.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,257P6@186801|Clostridia,3Y1PM@572511|Blautia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
NMLHFLOH_02138	457412.RSAG_00391	4.62e-178	496.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
NMLHFLOH_02139	1121115.AXVN01000004_gene1956	3.65e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_02140	1121115.AXVN01000004_gene1955	1.71e-265	726.0	COG1835@1|root,COG1835@2|Bacteria,1U1IX@1239|Firmicutes,25J4S@186801|Clostridia,3Y0VP@572511|Blautia	186801|Clostridia	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NMLHFLOH_02141	1121115.AXVN01000004_gene1954	4.89e-266	728.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3Y04U@572511|Blautia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NMLHFLOH_02142	1121115.AXVN01000004_gene1953	6.7e-271	738.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
NMLHFLOH_02143	1121115.AXVN01000004_gene1952	4.96e-316	859.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3Y1R0@572511|Blautia	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NMLHFLOH_02144	1121115.AXVN01000004_gene1951	2.94e-97	282.0	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
NMLHFLOH_02145	457412.RSAG_00384	1.98e-301	822.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NMLHFLOH_02146	1121115.AXVN01000004_gene1949	0.0	1961.0	COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,25KH4@186801|Clostridia,3Y05H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
NMLHFLOH_02147	1121115.AXVN01000004_gene1948	3.37e-176	492.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NMLHFLOH_02148	1121115.AXVN01000004_gene1947	7.57e-61	186.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
NMLHFLOH_02149	1121115.AXVN01000004_gene1946	4.38e-102	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NMLHFLOH_02150	457412.RSAG_00378	0.0	878.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NMLHFLOH_02151	1121115.AXVN01000004_gene1944	0.0	897.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NMLHFLOH_02152	1121115.AXVN01000004_gene1943	7.3e-121	344.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NMLHFLOH_02153	457412.RSAG_00375	4.17e-119	340.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3WJBW@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NMLHFLOH_02154	1121115.AXVN01000004_gene1941	3.66e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NMLHFLOH_02155	1121115.AXVN01000004_gene1940	1.02e-231	639.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
NMLHFLOH_02156	457412.RSAG_00371	5.88e-132	374.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_02159	1121115.AXVN01000004_gene1939	8.87e-162	453.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_02160	457412.RSAG_00367	0.0	1004.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WSQQ@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_02161	457412.RSAG_00365	3.87e-154	432.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NMLHFLOH_02162	1121115.AXVN01000004_gene1936	6.86e-177	493.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3XZ31@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NMLHFLOH_02163	1121115.AXVN01000004_gene1935	4.9e-172	478.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,3XYSN@572511|Blautia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NMLHFLOH_02164	457412.RSAG_00362	0.0	1010.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WH0Z@541000|Ruminococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NMLHFLOH_02165	457412.RSAG_00361	0.0	2804.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
NMLHFLOH_02166	1121115.AXVN01000004_gene1932	2.08e-287	783.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
NMLHFLOH_02167	1121115.AXVN01000004_gene1930	8.14e-63	192.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NMLHFLOH_02168	1121115.AXVN01000004_gene1929	4.82e-254	697.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NMLHFLOH_02169	457412.RSAG_02035	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
NMLHFLOH_02170	1121115.AXVN01000094_gene766	1.05e-101	294.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NMLHFLOH_02171	1121115.AXVN01000094_gene765	3.85e-180	501.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NMLHFLOH_02172	1121115.AXVN01000094_gene764	2.89e-181	505.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NMLHFLOH_02173	1121115.AXVN01000094_gene763	1.54e-249	686.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZ7W@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NMLHFLOH_02174	1121115.AXVN01000094_gene762	8.15e-204	563.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NMLHFLOH_02175	457412.RSAG_02041	2.08e-139	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
NMLHFLOH_02176	457412.RSAG_02042	0.0	1461.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NMLHFLOH_02177	457412.RSAG_02043	6.6e-312	850.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NMLHFLOH_02178	1121115.AXVN01000094_gene758	2.01e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NMLHFLOH_02179	1121115.AXVN01000094_gene757	1.26e-288	790.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NMLHFLOH_02180	1121115.AXVN01000094_gene756	1.17e-124	355.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3Y01K@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NMLHFLOH_02181	1121115.AXVN01000094_gene755	0.0	979.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_02182	457412.RSAG_02051	1.3e-104	302.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
NMLHFLOH_02183	1121115.AXVN01000189_gene1038	3.39e-183	510.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NMLHFLOH_02184	457412.RSAG_02053	9.97e-103	297.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NMLHFLOH_02185	1121115.AXVN01000180_gene2884	0.0	866.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3Y1CE@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02186	1121115.AXVN01000180_gene2885	1.01e-223	615.0	COG2207@1|root,COG2207@2|Bacteria,1VT0T@1239|Firmicutes,24YTA@186801|Clostridia,3Y0YN@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_02187	457412.RSAG_02056	4.89e-146	411.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3WJ59@541000|Ruminococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NMLHFLOH_02188	457412.RSAG_02057	0.0	956.0	2EI9P@1|root,33C11@2|Bacteria,1VNEN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02189	457412.RSAG_02058	1.25e-299	818.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3WJPZ@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_02190	457412.RSAG_02059	1.56e-152	429.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,25M0T@186801|Clostridia,3WP4W@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_02191	457412.RSAG_02060	7.56e-62	189.0	2DZYH@1|root,32XJC@2|Bacteria,1VGUH@1239|Firmicutes,25HRQ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
NMLHFLOH_02192	457412.RSAG_02061	1.02e-59	183.0	2E3EN@1|root,32YDN@2|Bacteria,1VDEB@1239|Firmicutes,25FXN@186801|Clostridia,3WMJY@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
NMLHFLOH_02193	1121115.AXVN01000133_gene741	4.33e-227	631.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NMLHFLOH_02194	457412.RSAG_02063	1.88e-131	373.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia,3WJKF@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
NMLHFLOH_02195	457412.RSAG_02064	8.39e-194	538.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
NMLHFLOH_02196	457412.RSAG_02065	2.87e-305	834.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,25DEX@186801|Clostridia,3WSGH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
NMLHFLOH_02197	457412.RSAG_02066	3.83e-68	206.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3WJM5@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NMLHFLOH_02198	1121115.AXVN01000079_gene2735	4.6e-219	603.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,3Y1A4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02199	457412.RSAG_02082	3.23e-36	123.0	2C4UK@1|root,346TK@2|Bacteria,1W0FK@1239|Firmicutes,2530T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02200	457412.RSAG_02083	1.01e-35	120.0	2E7J1@1|root,33DKE@2|Bacteria,1VM3N@1239|Firmicutes,24VIG@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02201	1121115.AXVN01000183_gene2442	3.76e-39	138.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,3Y0U3@572511|Blautia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NMLHFLOH_02202	742735.HMPREF9467_01906	9.31e-56	188.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,221ZR@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NMLHFLOH_02203	428125.CLOLEP_01969	3.2e-101	304.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3WJJZ@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	amyC	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_02204	1235802.C823_01802	7.27e-132	383.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,25UYX@186806|Eubacteriaceae	186801|Clostridia	P	permease	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_02205	1235802.C823_01801	6.41e-167	488.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NMLHFLOH_02206	697284.ERIC2_c33400	6.41e-76	243.0	COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,4HD7B@91061|Bacilli,274HM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03435	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NMLHFLOH_02207	1437610.BREU_2246	2.52e-186	536.0	COG1621@1|root,COG1621@2|Bacteria,2H3S0@201174|Actinobacteria,4D05M@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NMLHFLOH_02208	1256908.HMPREF0373_01253	4.65e-58	192.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25ZV2@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NMLHFLOH_02209	457412.RSAG_02446	7.71e-255	698.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_02210	1121115.AXVN01000001_gene1077	9.06e-182	505.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NMLHFLOH_02211	457412.RSAG_01192	1.08e-113	326.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
NMLHFLOH_02212	1121115.AXVN01000001_gene1079	3.47e-40	133.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NMLHFLOH_02213	1121115.AXVN01000001_gene1080	1.77e-51	162.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NMLHFLOH_02214	1121115.AXVN01000001_gene1081	4.29e-310	847.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NMLHFLOH_02215	1121115.AXVN01000001_gene1082	1.92e-67	204.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NMLHFLOH_02216	891391.LAC30SC_01360	5.28e-54	191.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	int7	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NMLHFLOH_02220	887325.HMPREF0381_1082	1.54e-50	165.0	2ET36@1|root,33KMC@2|Bacteria,1VKQN@1239|Firmicutes,24UID@186801|Clostridia,1HW30@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
NMLHFLOH_02221	97138.C820_01991	1.47e-19	81.6	28ZUF@1|root,2ZMJ3@2|Bacteria,1W3ZG@1239|Firmicutes,256RM@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02223	1232453.BAIF02000002_gene1280	1.02e-56	191.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,267PJ@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NMLHFLOH_02224	397291.C804_01604	8.67e-84	257.0	COG1484@1|root,COG1484@2|Bacteria,1V8DQ@1239|Firmicutes,24M56@186801|Clostridia,27NQC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
NMLHFLOH_02225	1507.HMPREF0262_00303	8.28e-73	229.0	COG3935@1|root,COG3935@2|Bacteria,1TQT6@1239|Firmicutes,24I78@186801|Clostridia,36JE7@31979|Clostridiaceae	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02227	1235798.C817_05064	3.2e-13	64.7	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24US2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02228	500632.CLONEX_03572	2.52e-14	67.8	2DE0W@1|root,2ZK1Y@2|Bacteria,1W4QD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02229	1121115.AXVN01000006_gene2173	3.76e-09	61.6	COG1396@1|root,COG1396@2|Bacteria,1UVI3@1239|Firmicutes,24SEF@186801|Clostridia,3Y1RY@572511|Blautia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02230	1235799.C818_02250	1.36e-284	779.0	COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,248VD@186801|Clostridia,27KR8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NMLHFLOH_02231	1121115.AXVN01000001_gene1093	1.99e-285	780.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NMLHFLOH_02232	1121115.AXVN01000001_gene1094	3.89e-216	598.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NMLHFLOH_02233	457412.RSAG_04662	0.0	1937.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WH4V@541000|Ruminococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
NMLHFLOH_02234	1121115.AXVN01000001_gene1096	8.03e-159	445.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NMLHFLOH_02235	1121115.AXVN01000001_gene1097	6.78e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NMLHFLOH_02236	1121115.AXVN01000001_gene1098	6.17e-238	655.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NMLHFLOH_02237	457412.RSAG_01204	0.0	1160.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3WGT9@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NMLHFLOH_02238	457412.RSAG_01205	3.57e-176	494.0	2ESCZ@1|root,33JXR@2|Bacteria,1VRFX@1239|Firmicutes,24YXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02239	457412.RSAG_01206	2.58e-166	465.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,3WRJJ@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_02240	1121115.AXVN01000001_gene1102	0.0	1230.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_02241	1121115.AXVN01000001_gene1103	0.0	1370.0	2E7W1@1|root,332AT@2|Bacteria,1UYG9@1239|Firmicutes,24B0R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02242	1121115.AXVN01000001_gene1104	1.12e-306	838.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYPG@572511|Blautia	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02243	1121115.AXVN01000001_gene1105	3.15e-38	127.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NMLHFLOH_02244	457412.RSAG_01211	2.07e-124	354.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NMLHFLOH_02245	457412.RSAG_01212	4.23e-306	834.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NMLHFLOH_02246	457412.RSAG_01213	1.34e-232	641.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NMLHFLOH_02247	457412.RSAG_04661	1.94e-313	856.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NMLHFLOH_02248	1121115.AXVN01000001_gene1110	2.67e-179	500.0	COG2865@1|root,COG2865@2|Bacteria,1TQXE@1239|Firmicutes,249ND@186801|Clostridia,3XZUK@572511|Blautia	186801|Clostridia	K	COG NOG11764 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02249	1121115.AXVN01000001_gene1111	1.51e-85	253.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
NMLHFLOH_02250	1121115.AXVN01000187_gene1812	7.03e-289	788.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,3XZIJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
NMLHFLOH_02251	1121115.AXVN01000187_gene1813	9.77e-34	115.0	2EI8P@1|root,332BW@2|Bacteria,1VFSF@1239|Firmicutes,24RRY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02252	457412.RSAG_01339	3.87e-305	830.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3WGFU@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NMLHFLOH_02253	457412.RSAG_01340	0.0	952.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3WGCT@541000|Ruminococcaceae	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NMLHFLOH_02254	1121115.AXVN01000041_gene2599	0.0	961.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NMLHFLOH_02255	1121115.AXVN01000041_gene2598	3.23e-59	183.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NMLHFLOH_02256	457412.RSAG_01343	0.0	894.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3WRU0@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
NMLHFLOH_02257	457412.RSAG_01344	1.6e-121	347.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3WK4K@541000|Ruminococcaceae	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
NMLHFLOH_02258	1121115.AXVN01000041_gene2595	0.0	893.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NMLHFLOH_02259	1121115.AXVN01000041_gene2594	1.38e-82	244.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,24I04@186801|Clostridia	186801|Clostridia	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
NMLHFLOH_02260	457412.RSAG_01347	2.17e-56	175.0	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,24Q65@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
NMLHFLOH_02261	457412.RSAG_01348	2.51e-262	721.0	2F0KS@1|root,33TPE@2|Bacteria,1VTU9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02262	457412.RSAG_04651	7.29e-77	229.0	COG4175@1|root,COG4175@2|Bacteria	2|Bacteria	E	quaternary-ammonium-compound-transporting ATPase activity	proV	-	3.6.3.32	ko:K02000	ko02010,map02010	M00208	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	-	ABC_tran,CBS
NMLHFLOH_02263	457412.RSAG_04650	8.74e-57	176.0	COG1131@1|root,COG1131@2|Bacteria,1V4NG@1239|Firmicutes	1239|Firmicutes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NMLHFLOH_02264	457412.RSAG_01350	3.01e-190	529.0	COG0789@1|root,COG0789@2|Bacteria,1UZ91@1239|Firmicutes,249BQ@186801|Clostridia,3WS79@541000|Ruminococcaceae	186801|Clostridia	K	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,MerR_1,RDD
NMLHFLOH_02265	457412.RSAG_01351	1.13e-21	84.3	2C5R4@1|root,2ZP19@2|Bacteria,1W6F9@1239|Firmicutes,255YP@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NMLHFLOH_02266	457412.RSAG_01352	1.25e-51	162.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NMLHFLOH_02267	457412.RSAG_01354	0.0	993.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3WGBX@541000|Ruminococcaceae	186801|Clostridia	C	glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NMLHFLOH_02268	457412.RSAG_01355	0.0	2990.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3WHE2@541000|Ruminococcaceae	186801|Clostridia	E	glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NMLHFLOH_02269	457412.RSAG_01356	0.0	1082.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NMLHFLOH_02270	1121115.AXVN01000041_gene2584	2.26e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NMLHFLOH_02271	457412.RSAG_01358	0.0	939.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NMLHFLOH_02272	1121115.AXVN01000041_gene2582	0.0	1387.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZ1H@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NMLHFLOH_02273	1121115.AXVN01000041_gene2581	0.0	1110.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3XYYP@572511|Blautia	186801|Clostridia	P	COG COG0004 Ammonia permease	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
NMLHFLOH_02274	1121115.AXVN01000041_gene2580	1.33e-27	100.0	2FHG3@1|root,349A5@2|Bacteria,1W08H@1239|Firmicutes,2530C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02276	457412.RSAG_04649	1.4e-69	210.0	2EQXM@1|root,33IHB@2|Bacteria,1VXES@1239|Firmicutes,251R2@186801|Clostridia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NMLHFLOH_02277	457412.RSAG_01363	1.1e-80	239.0	2F0TM@1|root,33TVK@2|Bacteria,1VV0H@1239|Firmicutes,250FJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02278	457412.RSAG_01364	2.38e-109	317.0	COG4512@1|root,COG4512@2|Bacteria,1V7Q2@1239|Firmicutes,24KC5@186801|Clostridia	186801|Clostridia	KOT	Accessory gene regulator B	-	-	-	-	-	-	-	-	-	-	-	-	AgrB
NMLHFLOH_02279	1121115.AXVN01000041_gene2577	7.08e-26	95.5	2CCVY@1|root,33DUW@2|Bacteria,1VP6Q@1239|Firmicutes,24TVP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02280	1235802.C823_04404	9.72e-54	170.0	COG1396@1|root,COG1396@2|Bacteria,1VGTD@1239|Firmicutes,25P5X@186801|Clostridia,25ZCJ@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_02281	1121115.AXVN01000041_gene2576	8.69e-167	466.0	COG3279@1|root,COG3279@2|Bacteria,1V140@1239|Firmicutes,24C89@186801|Clostridia,3Y0PE@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NMLHFLOH_02282	457412.RSAG_01368	4.73e-302	825.0	COG0642@1|root,COG0642@2|Bacteria,1UICJ@1239|Firmicutes,24NYC@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_02283	457412.RSAG_01370	1.06e-106	308.0	COG1853@1|root,COG1853@2|Bacteria,1UYJS@1239|Firmicutes,24DWF@186801|Clostridia,3WRH6@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NMLHFLOH_02284	1121115.AXVN01000041_gene2574	3.54e-148	417.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
NMLHFLOH_02285	1519439.JPJG01000022_gene552	2.77e-42	144.0	COG1396@1|root,COG1396@2|Bacteria,1UM3W@1239|Firmicutes,25GA1@186801|Clostridia	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_02286	1235799.C818_03007	1.23e-21	86.7	2DCK0@1|root,2ZEG2@2|Bacteria,1W2D4@1239|Firmicutes,255S2@186801|Clostridia,27SV0@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02288	665950.HMPREF1025_00892	4.99e-228	629.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_02289	457412.RSAG_00859	1.79e-88	259.0	2DH0B@1|root,2ZXXZ@2|Bacteria,1W4MJ@1239|Firmicutes,257EH@186801|Clostridia	457412.RSAG_00859|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02290	545696.HOLDEFILI_01786	6.86e-17	78.2	28IR3@1|root,2Z8QN@2|Bacteria,1UKI8@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791,DUF3990
NMLHFLOH_02291	622312.ROSEINA2194_00607	7.62e-39	130.0	2E7JW@1|root,33220@2|Bacteria,1VFQV@1239|Firmicutes,24WME@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02292	1121115.AXVN01000045_gene2050	4.14e-162	454.0	COG0664@1|root,COG0664@2|Bacteria,1V39R@1239|Firmicutes,24C2I@186801|Clostridia,3XZTI@572511|Blautia	186801|Clostridia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NMLHFLOH_02293	1121115.AXVN01000045_gene2051	5.86e-259	707.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3XZSA@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
NMLHFLOH_02294	1121115.AXVN01000045_gene2052	1.02e-192	534.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3XYPT@572511|Blautia	186801|Clostridia	C	Oxidoreductase NAD-binding domain	asrB	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NMLHFLOH_02295	1121115.AXVN01000045_gene2053	1.19e-232	640.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3XZCG@572511|Blautia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	asrC	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_10,Fer4_21,Fer4_4,Fer4_6,NIR_SIR,NIR_SIR_ferr
NMLHFLOH_02296	1121115.AXVN01000045_gene2056	0.0	1048.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3XZ89@572511|Blautia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
NMLHFLOH_02297	1121115.AXVN01000045_gene2057	2.63e-155	438.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3XZ8P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NMLHFLOH_02298	457412.RSAG_00854	1.56e-162	455.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NMLHFLOH_02299	457412.RSAG_00853	0.0	1707.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WN7G@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
NMLHFLOH_02300	457412.RSAG_00852	0.0	1323.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,dCache_1
NMLHFLOH_02301	457412.RSAG_00851	7.03e-246	676.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NMLHFLOH_02302	1121115.AXVN01000045_gene2063	9.68e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYPM@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02303	1121115.AXVN01000045_gene2064	4.74e-176	492.0	2DM3M@1|root,31JZR@2|Bacteria,1V8CM@1239|Firmicutes,24KFB@186801|Clostridia	186801|Clostridia	M	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_02304	457412.RSAG_00848	0.0	2373.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3WH59@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02305	457412.RSAG_00847	7.33e-311	845.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3WK5B@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02306	1121115.AXVN01000045_gene2067	3.25e-181	505.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia,3Y2D0@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02307	1121115.AXVN01000045_gene2068	1.93e-190	531.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3XYR5@572511|Blautia	186801|Clostridia	ET	cystine-binding periplasmic protein precursor	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NMLHFLOH_02308	1121115.AXVN01000045_gene2069	2.44e-134	382.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3XYV9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
NMLHFLOH_02309	1121115.AXVN01000045_gene2070	2.04e-157	442.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZJ5@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NMLHFLOH_02310	1121115.AXVN01000045_gene2071	0.0	930.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NMLHFLOH_02311	457412.RSAG_00842	0.0	872.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3WGUF@541000|Ruminococcaceae	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NMLHFLOH_02312	1121115.AXVN01000045_gene2073	1.35e-199	552.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
NMLHFLOH_02313	1121115.AXVN01000006_gene2188	1.52e-124	354.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
NMLHFLOH_02314	457412.RSAG_00839	3.28e-122	348.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NMLHFLOH_02315	1121115.AXVN01000006_gene2186	8.31e-209	577.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NMLHFLOH_02316	1121115.AXVN01000006_gene2185	4.58e-204	565.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
NMLHFLOH_02317	1121115.AXVN01000006_gene2184	5.6e-159	446.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NMLHFLOH_02318	457412.RSAG_00835	1.85e-266	728.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3WHUE@541000|Ruminococcaceae	186801|Clostridia	C	pyruvate formate lyase activating	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NMLHFLOH_02319	1121115.AXVN01000098_gene2878	1.06e-299	816.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3XZP1@572511|Blautia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
NMLHFLOH_02320	1121115.AXVN01000098_gene2879	6.36e-222	615.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NMLHFLOH_02321	1121115.AXVN01000098_gene2880	4.43e-191	532.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
NMLHFLOH_02322	1121115.AXVN01000098_gene2881	1.24e-79	236.0	2DYSA@1|root,34AWR@2|Bacteria,1VZ6D@1239|Firmicutes,250AC@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NMLHFLOH_02323	457412.RSAG_01930	7.97e-98	284.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NMLHFLOH_02324	457412.RSAG_01929	1.17e-206	574.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02325	457412.RSAG_01928	5.5e-284	775.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
NMLHFLOH_02326	457412.RSAG_01927	1.41e-114	328.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,3WJN7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD
NMLHFLOH_02327	457412.RSAG_01925	1.78e-134	381.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WK21@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_02328	1121115.AXVN01000078_gene2825	0.0	1126.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NMLHFLOH_02329	1121115.AXVN01000078_gene2826	4.83e-276	755.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
NMLHFLOH_02330	457412.RSAG_01922	3.99e-134	381.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3WKAY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NMLHFLOH_02331	457412.RSAG_01921	7.4e-292	798.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
NMLHFLOH_02332	457412.RSAG_01920	1.18e-233	645.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3WJ50@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_02333	1121115.AXVN01000078_gene2830	1.5e-197	548.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3Y0BN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NMLHFLOH_02334	1121115.AXVN01000078_gene2831	0.0	900.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZQF@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02335	180332.JTGN01000016_gene1038	0.0	985.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NMLHFLOH_02337	1499684.CCNP01000018_gene1285	4.33e-67	223.0	COG2972@1|root,COG2972@2|Bacteria,1UZ6F@1239|Firmicutes,24C2W@186801|Clostridia,36IQD@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NMLHFLOH_02338	1499684.CCNP01000018_gene1286	7.94e-55	195.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UZCE@1239|Firmicutes,24C9H@186801|Clostridia,36IKC@31979|Clostridiaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NMLHFLOH_02339	1123300.AUIN01000019_gene1104	9.51e-12	74.7	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,4HEMB@91061|Bacilli	91061|Bacilli	G	Bacterial extracellular solute-binding protein	msmE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02340	358681.BBR47_17110	2.17e-126	379.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,4HA29@91061|Bacilli,274K4@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02341	1304866.K413DRAFT_2105	1.99e-106	318.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,36HHS@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_02342	796945.HMPREF1145_1566	3.05e-113	334.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,2PQWV@265975|Oribacterium	186801|Clostridia	P	ABC transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_02343	592026.GCWU0000282_000246	1.13e-233	649.0	COG0673@1|root,COG0673@2|Bacteria,1V0JH@1239|Firmicutes,249FB@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NMLHFLOH_02344	411459.RUMOBE_02645	2.4e-283	805.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,3XZ09@572511|Blautia	186801|Clostridia	G	COG NOG04001 non supervised orthologous group	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
NMLHFLOH_02345	471875.RUMLAC_01888	1.91e-173	489.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WSRR@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NMLHFLOH_02346	471875.RUMLAC_01889	6.85e-209	585.0	COG2334@1|root,COG2334@2|Bacteria,1VRV5@1239|Firmicutes,25EGP@186801|Clostridia,3WHGG@541000|Ruminococcaceae	186801|Clostridia	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
NMLHFLOH_02347	1121115.AXVN01000078_gene2832	1.47e-216	599.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3XYZZ@572511|Blautia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NMLHFLOH_02350	1121115.AXVN01000078_gene2834	2.74e-195	544.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3XYRQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NMLHFLOH_02352	1121115.AXVN01000032_gene376	0.0	1110.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NMLHFLOH_02354	1121115.AXVN01000032_gene374	4.58e-38	132.0	28SNZ@1|root,2ZEZ7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02355	1121115.AXVN01000134_gene415	5.37e-312	848.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3XZ64@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NMLHFLOH_02356	1121115.AXVN01000134_gene414	3.32e-304	828.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3XZ80@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
NMLHFLOH_02357	1121115.AXVN01000134_gene413	0.0	900.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_02358	1121115.AXVN01000134_gene412	7.38e-295	803.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
NMLHFLOH_02359	1121115.AXVN01000134_gene411	2.38e-224	618.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NMLHFLOH_02360	457412.RSAG_04726	4.3e-159	446.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NMLHFLOH_02361	457412.RSAG_00195	2.58e-165	462.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02362	457412.RSAG_00196	2.75e-212	586.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
NMLHFLOH_02363	1121115.AXVN01000025_gene963	4.4e-117	335.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3XZZI@572511|Blautia	186801|Clostridia	C	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NMLHFLOH_02364	1121115.AXVN01000025_gene962	4.7e-205	568.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
NMLHFLOH_02365	457412.RSAG_00199	0.0	1512.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NMLHFLOH_02366	457412.RSAG_00200	3.71e-94	276.0	COG1148@1|root,COG1148@2|Bacteria,1V4P9@1239|Firmicutes,24IV2@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NMLHFLOH_02367	1121115.AXVN01000025_gene959	0.0	1754.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NMLHFLOH_02368	457412.RSAG_00202	0.0	1974.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3WRQE@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NMLHFLOH_02369	1121115.AXVN01000025_gene957	0.0	915.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NMLHFLOH_02370	1121115.AXVN01000025_gene956	4.4e-149	418.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3XZUY@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NMLHFLOH_02371	1121115.AXVN01000025_gene955	4.69e-86	253.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
NMLHFLOH_02372	1121115.AXVN01000025_gene954	8.69e-183	508.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NMLHFLOH_02373	1121115.AXVN01000025_gene953	8.67e-124	353.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NMLHFLOH_02374	1121115.AXVN01000025_gene952	1.26e-244	672.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NMLHFLOH_02375	1121115.AXVN01000025_gene951	1.24e-89	263.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,257NM@186801|Clostridia,3Y0BG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
NMLHFLOH_02376	1121115.AXVN01000025_gene950	2.09e-220	608.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
NMLHFLOH_02377	1121115.AXVN01000025_gene949	0.0	1775.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NMLHFLOH_02378	457412.RSAG_00212	0.0	2337.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
NMLHFLOH_02379	457412.RSAG_02724	9.65e-65	197.0	2E7YJ@1|root,332CZ@2|Bacteria,1VF30@1239|Firmicutes,24SCF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02380	457412.RSAG_02725	5.51e-200	553.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3WGHY@541000|Ruminococcaceae	186801|Clostridia	L	8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
NMLHFLOH_02381	1121115.AXVN01000090_gene2560	2.83e-62	190.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,2586D@186801|Clostridia,3Y0CI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
NMLHFLOH_02383	1121115.AXVN01000090_gene2570	0.0	873.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
NMLHFLOH_02384	1121115.AXVN01000090_gene2571	2.93e-138	390.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
NMLHFLOH_02385	1121115.AXVN01000090_gene2572	9.16e-304	827.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NMLHFLOH_02386	1121115.AXVN01000012_gene3090	1.05e-179	501.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NMLHFLOH_02387	1121115.AXVN01000012_gene3091	7.54e-40	132.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NMLHFLOH_02388	1121115.AXVN01000012_gene3092	3.45e-273	756.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NMLHFLOH_02389	457412.RSAG_02735	1.51e-180	501.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,3WI6A@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NMLHFLOH_02390	1121115.AXVN01000012_gene3103	2.04e-160	450.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NMLHFLOH_02391	457412.RSAG_02744	8.82e-265	725.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3WH26@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NMLHFLOH_02392	457412.RSAG_02745	5.44e-176	490.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3WH3N@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
NMLHFLOH_02393	1121115.AXVN01000012_gene3106	8.74e-196	543.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,3XZRH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NMLHFLOH_02394	1121115.AXVN01000012_gene3107	0.0	1037.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NMLHFLOH_02395	1121115.AXVN01000012_gene3108	1.25e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NMLHFLOH_02396	1121115.AXVN01000012_gene3109	1.52e-208	578.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NMLHFLOH_02397	1121115.AXVN01000012_gene3110	0.0	938.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia,3Y14C@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02398	1121115.AXVN01000012_gene3111	6.84e-225	619.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3Y1E9@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NMLHFLOH_02399	1121115.AXVN01000012_gene3112	0.0	1078.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia	186801|Clostridia	G	family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
NMLHFLOH_02400	1121115.AXVN01000012_gene3113	1.86e-248	679.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NMLHFLOH_02401	457412.RSAG_02749	9.42e-232	636.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3WN40@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
NMLHFLOH_02402	1121115.AXVN01000012_gene3115	0.0	1287.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y14N@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NMLHFLOH_02403	1121115.AXVN01000012_gene3116	2.87e-61	187.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24QSZ@186801|Clostridia,3Y27B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02404	1121115.AXVN01000012_gene3117	0.0	1057.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NMLHFLOH_02405	457412.RSAG_02755	2.18e-211	582.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WJRY@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
NMLHFLOH_02406	1235802.C823_05668	1.87e-43	142.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NMLHFLOH_02407	1121115.AXVN01000012_gene3142	6.01e-270	741.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3XZFH@572511|Blautia	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
NMLHFLOH_02408	457412.RSAG_02776	0.0	1232.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia,3WH1R@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NMLHFLOH_02409	457412.RSAG_02777	0.0	1078.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3WJUQ@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
NMLHFLOH_02410	457412.RSAG_02778	2.24e-148	417.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,3WJCI@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NMLHFLOH_02411	1121115.AXVN01000012_gene3146	8.96e-145	415.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y03X@572511|Blautia	186801|Clostridia	C	COG COG1454 Alcohol dehydrogenase, class IV	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NMLHFLOH_02412	457412.RSAG_03051	1.63e-90	293.0	COG5263@1|root,COG5492@1|root,COG5263@2|Bacteria,COG5492@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02413	457412.RSAG_03050	0.0	1337.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3WIA4@541000|Ruminococcaceae	186801|Clostridia	L	TopoisomeraseII	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NMLHFLOH_02414	457412.RSAG_03049	0.0	1452.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3WGU9@541000|Ruminococcaceae	186801|Clostridia	L	DNA Topoisomerase IV	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NMLHFLOH_02415	1121115.AXVN01000005_gene2220	9.83e-106	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
NMLHFLOH_02416	457412.RSAG_03047	1.78e-254	702.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NMLHFLOH_02417	1121115.AXVN01000005_gene2222	4.94e-58	179.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
NMLHFLOH_02418	457412.RSAG_03045	4.9e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3WM5W@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
NMLHFLOH_02419	457412.RSAG_03044	0.0	1601.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NMLHFLOH_02420	1121115.AXVN01000005_gene2225	4.61e-84	248.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NMLHFLOH_02421	457412.RSAG_03042	4.01e-235	646.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NMLHFLOH_02422	457412.RSAG_03041	1.86e-211	584.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
NMLHFLOH_02423	1121115.AXVN01000005_gene2228	4.24e-217	598.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3XZMT@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NMLHFLOH_02424	1121115.AXVN01000005_gene2229	8.72e-53	166.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NMLHFLOH_02425	457412.RSAG_03038	0.0	1358.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NMLHFLOH_02426	1121115.AXVN01000005_gene2231	5.93e-115	328.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3XZW3@572511|Blautia	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NMLHFLOH_02427	1121115.AXVN01000005_gene2232	9.99e-120	342.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24GHG@186801|Clostridia,3XZTE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
NMLHFLOH_02428	1121115.AXVN01000005_gene2233	1.26e-289	790.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3XZSQ@572511|Blautia	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
NMLHFLOH_02429	1121115.AXVN01000005_gene2234	6.1e-189	524.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3XZCT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02430	1121115.AXVN01000005_gene2235	0.0	1721.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NMLHFLOH_02431	1121115.AXVN01000005_gene2236	1.03e-84	249.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NMLHFLOH_02432	1121115.AXVN01000005_gene2237	5.95e-191	528.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3XYR4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NMLHFLOH_02433	1121115.AXVN01000005_gene2238	0.0	1301.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase
NMLHFLOH_02434	1121115.AXVN01000005_gene2239	1.68e-141	398.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02435	457412.RSAG_03029	0.0	932.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NMLHFLOH_02436	1121115.AXVN01000005_gene2241	3.55e-282	769.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3XZ23@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NMLHFLOH_02437	457412.RSAG_03027	3.22e-135	383.0	2C0IG@1|root,324G4@2|Bacteria,1UQRN@1239|Firmicutes,258HV@186801|Clostridia,3WMTD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02438	457412.RSAG_03026	0.0	1938.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
NMLHFLOH_02439	457412.RSAG_03025	2.37e-218	602.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NMLHFLOH_02440	457412.RSAG_03024	3.03e-179	499.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3WJ6A@541000|Ruminococcaceae	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NMLHFLOH_02441	1121115.AXVN01000005_gene2246	0.0	967.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NMLHFLOH_02442	1121115.AXVN01000030_gene3615	2.71e-240	662.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NMLHFLOH_02443	457412.RSAG_03363	3.3e-174	484.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
NMLHFLOH_02444	457412.RSAG_03362	3.06e-120	343.0	COG0454@1|root,COG0454@2|Bacteria,1V9X4@1239|Firmicutes,24G56@186801|Clostridia,3WSS2@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NMLHFLOH_02445	1121115.AXVN01000030_gene3618	1.67e-50	159.0	2DDM6@1|root,32U1S@2|Bacteria,1URV4@1239|Firmicutes,259SN@186801|Clostridia,3Y1XH@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02446	1121115.AXVN01000030_gene3619	4.1e-251	688.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NMLHFLOH_02447	1121115.AXVN01000030_gene3620	1.62e-186	517.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,3Y0AU@572511|Blautia	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02448	457412.RSAG_03358	3.95e-295	804.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WS0T@541000|Ruminococcaceae	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
NMLHFLOH_02449	457412.RSAG_03357	0.0	933.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,3WJ5T@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NMLHFLOH_02450	1121115.AXVN01000030_gene3623	1.68e-103	298.0	2E4P6@1|root,32ZHX@2|Bacteria,1VCAE@1239|Firmicutes,24PE5@186801|Clostridia,3Y172@572511|Blautia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NMLHFLOH_02451	1121115.AXVN01000030_gene3624	1.29e-128	365.0	COG0500@1|root,COG2226@2|Bacteria,1UDBU@1239|Firmicutes,25I0S@186801|Clostridia,3Y12S@572511|Blautia	186801|Clostridia	H	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NMLHFLOH_02452	1121115.AXVN01000030_gene3625	2.77e-49	156.0	2EGAW@1|root,33A2R@2|Bacteria,1VMAM@1239|Firmicutes,24WIE@186801|Clostridia,3Y1R7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02453	457412.RSAG_03353	0.0	1541.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WNTW@541000|Ruminococcaceae	186801|Clostridia	CE	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,Pyr_redox_2
NMLHFLOH_02454	1121115.AXVN01000030_gene3627	0.0	1865.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3Y192@572511|Blautia	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	1.2.99.7	ko:K07469	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NMLHFLOH_02455	1121115.AXVN01000030_gene3628	1.64e-56	175.0	2E80U@1|root,3094H@2|Bacteria,1U4EU@1239|Firmicutes,2520R@186801|Clostridia,3Y1V4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02456	1121115.AXVN01000030_gene3629	2.39e-226	623.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1V2BH@1239|Firmicutes,25CV9@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,NTP_transf_3
NMLHFLOH_02457	1121115.AXVN01000030_gene3630	3.32e-264	723.0	COG0406@1|root,COG1418@1|root,COG0406@2|Bacteria,COG1418@2|Bacteria,1TTYI@1239|Firmicutes,25KH7@186801|Clostridia,3Y1F0@572511|Blautia	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NMLHFLOH_02458	1121115.AXVN01000030_gene3631	6.79e-249	682.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3Y1BH@572511|Blautia	186801|Clostridia	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NMLHFLOH_02459	1121115.AXVN01000030_gene3632	4.06e-211	582.0	COG4122@1|root,COG4122@2|Bacteria,1VKRG@1239|Firmicutes,24HG7@186801|Clostridia,3Y11Q@572511|Blautia	186801|Clostridia	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
NMLHFLOH_02461	1121115.AXVN01000030_gene3637	4.57e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NMLHFLOH_02462	457412.RSAG_03345	6.29e-288	804.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3WJXH@541000|Ruminococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NMLHFLOH_02463	1121115.AXVN01000030_gene3639	4.29e-171	478.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_02464	1121115.AXVN01000030_gene3640	0.0	892.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NMLHFLOH_02465	457412.RSAG_03342	0.0	1128.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3WHYM@541000|Ruminococcaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
NMLHFLOH_02466	1121115.AXVN01000030_gene3642	5.61e-168	470.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3XZX5@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NMLHFLOH_02467	1121115.AXVN01000030_gene3643	2.2e-61	188.0	2CA4P@1|root,33W70@2|Bacteria,1VVK6@1239|Firmicutes,251F5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02468	457412.RSAG_04607	5.12e-38	127.0	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02469	457412.RSAG_03339	2.06e-38	128.0	2EMF6@1|root,33F40@2|Bacteria,1VPJF@1239|Firmicutes,24VFH@186801|Clostridia,3WQWU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02470	457412.RSAG_03338	3.48e-44	143.0	2CCVX@1|root,33G73@2|Bacteria,1VN7A@1239|Firmicutes,24W0K@186801|Clostridia,3WRAX@541000|Ruminococcaceae	186801|Clostridia	S	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
NMLHFLOH_02471	457412.RSAG_04608	0.0	883.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
NMLHFLOH_02472	457412.RSAG_03335	3.06e-67	203.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NMLHFLOH_02473	457412.RSAG_03502	0.0	902.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NMLHFLOH_02475	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02476	457412.RSAG_01469	2.59e-152	428.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,3WKZB@541000|Ruminococcaceae	186801|Clostridia	S	Thiamine transporter protein (Thia_YuaJ)	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
NMLHFLOH_02477	457412.RSAG_01468	3.57e-112	321.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NMLHFLOH_02478	1121115.AXVN01000065_gene686	5.59e-78	232.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
NMLHFLOH_02479	457412.RSAG_01466	3.6e-241	662.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,3WHAM@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
NMLHFLOH_02480	457412.RSAG_01465	4.34e-209	579.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NMLHFLOH_02481	457412.RSAG_01464	6.72e-152	426.0	2BC4V@1|root,325PN@2|Bacteria,1URQ2@1239|Firmicutes,24ZYA@186801|Clostridia,3WQB6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NMLHFLOH_02482	457412.RSAG_01463	0.0	1041.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,3WREU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02483	457412.RSAG_01462	1.05e-168	472.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,3WMED@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02484	457412.RSAG_01461	0.0	2677.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,3WJQR@541000|Ruminococcaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02486	1121115.AXVN01000069_gene2315	1.16e-118	339.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3Y0D0@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_02487	1121115.AXVN01000069_gene2316	3.69e-150	422.0	29XH4@1|root,30J7T@2|Bacteria,1UVPT@1239|Firmicutes,2503Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02488	1121115.AXVN01000069_gene2317	4.73e-193	537.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3XZ72@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NMLHFLOH_02489	1121115.AXVN01000069_gene2318	9.09e-298	814.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3XZ6V@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NMLHFLOH_02490	1121115.AXVN01000069_gene2319	6.07e-138	391.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3Y2B8@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NMLHFLOH_02491	1121115.AXVN01000069_gene2320	1.61e-64	197.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NMLHFLOH_02492	457412.RSAG_01453	4.46e-94	275.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia,3WJPG@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
NMLHFLOH_02493	457412.RSAG_01452	3.84e-315	860.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02494	457412.RSAG_01451	2.83e-104	301.0	COG1633@1|root,COG1633@2|Bacteria,1V72Y@1239|Firmicutes,24JY4@186801|Clostridia,3WKP1@541000|Ruminococcaceae	186801|Clostridia	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F,Rubrerythrin
NMLHFLOH_02495	457412.RSAG_01450	0.0	1153.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WGUV@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
NMLHFLOH_02496	457412.RSAG_01449	3.65e-316	862.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02497	457412.RSAG_01448	0.0	1425.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3WH88@541000|Ruminococcaceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NMLHFLOH_02499	457412.RSAG_01447	3.01e-297	809.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3WN9Q@541000|Ruminococcaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
NMLHFLOH_02500	1121115.AXVN01000010_gene2761	1.77e-62	191.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
NMLHFLOH_02501	1121115.AXVN01000010_gene2762	3.91e-82	243.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
NMLHFLOH_02502	457412.RSAG_01445	0.0	1146.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
NMLHFLOH_02503	1121115.AXVN01000010_gene2764	3.75e-119	340.0	2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,25HPJ@186801|Clostridia	186801|Clostridia	S	AmiS/UreI family transporter	-	-	-	ko:K03191	ko05120,map05120	-	-	-	ko00000,ko00001,ko02000	1.A.29.1.3,1.A.29.1.4,1.A.29.1.5	-	-	AmiS_UreI
NMLHFLOH_02504	1121115.AXVN01000010_gene2765	4.47e-113	324.0	COG2371@1|root,COG2371@2|Bacteria,1V7SB@1239|Firmicutes,25DT7@186801|Clostridia	186801|Clostridia	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
NMLHFLOH_02505	1121115.AXVN01000010_gene2766	3.83e-163	456.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
NMLHFLOH_02506	1121115.AXVN01000010_gene2767	6.7e-141	398.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
NMLHFLOH_02507	1121115.AXVN01000010_gene2768	2.24e-204	565.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,24D1J@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
NMLHFLOH_02508	457412.RSAG_02779	3.02e-71	224.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NMLHFLOH_02509	457412.RSAG_02780	1e-137	389.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia,3WRWC@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NMLHFLOH_02510	457412.RSAG_02781	1.86e-89	262.0	COG1895@1|root,COG1895@2|Bacteria,1VG5F@1239|Firmicutes,24RT7@186801|Clostridia,3WMCM@541000|Ruminococcaceae	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NMLHFLOH_02511	457412.RSAG_02782	8.61e-75	223.0	COG1708@1|root,COG1708@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07076	-	-	-	-	ko00000	-	-	-	NTP_transf_2
NMLHFLOH_02512	1121115.AXVN01000103_gene855	4.58e-119	340.0	COG5423@1|root,COG5423@2|Bacteria,1VBHK@1239|Firmicutes,24XGW@186801|Clostridia,3Y0MP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NMLHFLOH_02513	457412.RSAG_02784	9.83e-260	712.0	COG3608@1|root,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3WJ0E@541000|Ruminococcaceae	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA
NMLHFLOH_02514	457412.RSAG_02785	1.55e-79	236.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3WK18@541000|Ruminococcaceae	186801|Clostridia	K	regulatory protein, arsR	czrA	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NMLHFLOH_02515	457412.RSAG_02786	0.0	1174.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NMLHFLOH_02516	457412.RSAG_02787	4.15e-46	148.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3WKYW@541000|Ruminococcaceae	186801|Clostridia	C	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
NMLHFLOH_02517	457412.RSAG_02788	1.63e-314	858.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02518	457412.RSAG_04541	1.7e-233	642.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN6I@541000|Ruminococcaceae	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NMLHFLOH_02519	457412.RSAG_04542	2.05e-182	508.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WNXH@541000|Ruminococcaceae	186801|Clostridia	EP	ATPases associated with a variety of cellular activities	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NMLHFLOH_02520	457412.RSAG_02790	5.2e-188	523.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WIZI@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15586	ko02010,map02010	M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NMLHFLOH_02521	457412.RSAG_02791	1.72e-216	598.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WN70@541000|Ruminococcaceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NMLHFLOH_02522	457412.RSAG_02792	0.0	1040.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NMLHFLOH_02523	457412.RSAG_02793	7.57e-286	781.0	COG1609@1|root,COG1609@2|Bacteria,1UZFZ@1239|Firmicutes,24H13@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02524	457412.RSAG_02794	8.26e-274	748.0	COG3385@1|root,COG3385@2|Bacteria,1UNGW@1239|Firmicutes,24BMP@186801|Clostridia,3WK14@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
NMLHFLOH_02525	457412.RSAG_02795	0.0	941.0	COG1874@1|root,COG1874@2|Bacteria,1TRPS@1239|Firmicutes,24AH9@186801|Clostridia,3WIPR@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_42
NMLHFLOH_02526	457412.RSAG_02796	2.78e-148	418.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3WHWK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NMLHFLOH_02527	457412.RSAG_02797	6.38e-181	503.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NMLHFLOH_02528	457412.RSAG_02798	0.0	1199.0	COG5337@1|root,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia,3WI9H@541000|Ruminococcaceae	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
NMLHFLOH_02529	457412.RSAG_02799	0.0	938.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia,3WKMX@541000|Ruminococcaceae	186801|Clostridia	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
NMLHFLOH_02530	457412.RSAG_02800	0.0	987.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,3WGGZ@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
NMLHFLOH_02531	457412.RSAG_02801	0.0	1233.0	COG4878@1|root,COG4878@2|Bacteria,1TT2Y@1239|Firmicutes,24A4C@186801|Clostridia,3WIQH@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
NMLHFLOH_02532	457412.RSAG_02802	4.17e-205	568.0	28H6W@1|root,2Z7J7@2|Bacteria,1TPV9@1239|Firmicutes,24CD2@186801|Clostridia,3WMQ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02533	457412.RSAG_02803	0.0	1382.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,3WKD2@541000|Ruminococcaceae	186801|Clostridia	GM	Domain of unknown function (DUF4118)	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
NMLHFLOH_02534	457412.RSAG_02804	0.0	1403.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,3WI61@541000|Ruminococcaceae	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
NMLHFLOH_02535	457412.RSAG_02805	1.92e-159	446.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia,3WIY4@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NMLHFLOH_02536	1121115.AXVN01000103_gene865	5.31e-82	243.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes	1239|Firmicutes	K	repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NMLHFLOH_02537	457412.RSAG_02807	4.67e-52	164.0	COG1879@1|root,COG1879@2|Bacteria,1VX4B@1239|Firmicutes,251P0@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02538	457412.RSAG_03107	1.2e-96	281.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3WKMB@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NMLHFLOH_02539	457412.RSAG_03108	6.44e-122	347.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3WJCA@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NMLHFLOH_02540	457412.RSAG_03109	6.03e-290	791.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,3WGJY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NMLHFLOH_02541	1121115.AXVN01000076_gene2620	5.29e-197	545.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NMLHFLOH_02542	1121115.AXVN01000076_gene2621	1.45e-260	719.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3Y03A@572511|Blautia	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NMLHFLOH_02543	457412.RSAG_03112	0.0	2155.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NMLHFLOH_02544	1121115.AXVN01000076_gene2623	1.32e-138	391.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NMLHFLOH_02545	457412.RSAG_03114	9.1e-235	645.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NMLHFLOH_02546	1121115.AXVN01000076_gene2625	3.66e-209	586.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NMLHFLOH_02547	457412.RSAG_03117	6.13e-48	153.0	2E6AD@1|root,330Y9@2|Bacteria,1VFG8@1239|Firmicutes,24RI6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02548	1121115.AXVN01000076_gene2628	0.0	1323.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3XYYD@572511|Blautia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NMLHFLOH_02549	1121115.AXVN01000076_gene2629	2.84e-287	789.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia,3XYJW@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NMLHFLOH_02550	457412.RSAG_03120	9.25e-274	753.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3WKE4@541000|Ruminococcaceae	186801|Clostridia	M	Bacterial trigger factor protein (TF) C-terminus	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
NMLHFLOH_02551	457412.RSAG_03121	0.0	913.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NMLHFLOH_02552	457412.RSAG_03122	0.0	1000.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NMLHFLOH_02553	1121115.AXVN01000091_gene2603	7.73e-72	219.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02554	1121115.AXVN01000091_gene2604	5.7e-105	303.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NMLHFLOH_02555	1121115.AXVN01000091_gene2605	2.61e-196	544.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NMLHFLOH_02556	1121115.AXVN01000091_gene2606	2.19e-52	165.0	2C5NI@1|root,33W5Y@2|Bacteria,1VWK5@1239|Firmicutes,2519Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02557	1121115.AXVN01000091_gene2607	0.0	1098.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
NMLHFLOH_02558	1121115.AXVN01000091_gene2608	0.0	954.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3XZAJ@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
NMLHFLOH_02559	1121115.AXVN01000091_gene2609	4.75e-157	442.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NMLHFLOH_02560	1121115.AXVN01000091_gene2610	1.15e-204	566.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NMLHFLOH_02561	457412.RSAG_03131	0.0	998.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHGK@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NMLHFLOH_02562	1121115.AXVN01000091_gene2612	3.16e-93	272.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
NMLHFLOH_02563	457412.RSAG_03133	2.79e-174	486.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NMLHFLOH_02564	1121115.AXVN01000091_gene2614	2.48e-254	703.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_02565	1121115.AXVN01000049_gene1298	3.32e-147	414.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3XYHQ@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_02566	457412.RSAG_02923	0.0	1249.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NMLHFLOH_02567	457412.RSAG_02922	3.61e-211	583.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3WGR8@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NMLHFLOH_02568	1121115.AXVN01000049_gene1301	3.14e-275	754.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3XZBV@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
NMLHFLOH_02569	457412.RSAG_02920	1.9e-203	564.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3WHNT@541000|Ruminococcaceae	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
NMLHFLOH_02570	457412.RSAG_02919	2.58e-155	436.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3WGK4@541000|Ruminococcaceae	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
NMLHFLOH_02571	1121115.AXVN01000049_gene1304	1.19e-255	701.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NMLHFLOH_02572	457412.RSAG_02917	1.06e-199	554.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NMLHFLOH_02573	1121115.AXVN01000049_gene1306	3.11e-84	248.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
NMLHFLOH_02574	1121115.AXVN01000049_gene1307	0.0	1144.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
NMLHFLOH_02575	457412.RSAG_02914	0.0	1163.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NMLHFLOH_02576	1121115.AXVN01000049_gene1309	7.29e-215	593.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NMLHFLOH_02577	1121115.AXVN01000049_gene1310	0.0	1398.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZDZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NMLHFLOH_02578	457412.RSAG_02911	5.23e-229	630.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NMLHFLOH_02579	1121115.AXVN01000049_gene1312	2.84e-200	553.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia,3Y1CX@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NMLHFLOH_02580	1121115.AXVN01000049_gene1313	2.69e-182	507.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
NMLHFLOH_02581	1121115.AXVN01000049_gene1314	2.09e-288	787.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NMLHFLOH_02582	457412.RSAG_02906	9.83e-148	416.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3WJH1@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NMLHFLOH_02583	457412.RSAG_02905	1.17e-175	491.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NMLHFLOH_02584	1121115.AXVN01000049_gene1317	1.1e-231	639.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
NMLHFLOH_02585	1121115.AXVN01000049_gene1318	3.23e-134	380.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3XZUJ@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NMLHFLOH_02586	457412.RSAG_02902	0.0	972.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WHMI@541000|Ruminococcaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NMLHFLOH_02587	457412.RSAG_02901	0.0	894.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3WGM2@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
NMLHFLOH_02588	457412.RSAG_02900	4.62e-57	180.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02589	457412.RSAG_04591	0.0	893.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NMLHFLOH_02590	457412.RSAG_03502	1.68e-293	803.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NMLHFLOH_02591	1121115.AXVN01000066_gene3237	1.02e-231	636.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYY9@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NMLHFLOH_02592	1121115.AXVN01000066_gene3236	1.95e-272	744.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	APH
NMLHFLOH_02593	457412.RSAG_01985	8.3e-253	692.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
NMLHFLOH_02594	1121115.AXVN01000066_gene3234	1.32e-43	142.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24W8T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02595	411469.EUBHAL_01995	6.97e-34	117.0	COG2026@1|root,COG2026@2|Bacteria,1VCJ7@1239|Firmicutes,24Q49@186801|Clostridia,25XS6@186806|Eubacteriaceae	186801|Clostridia	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NMLHFLOH_02596	457412.RSAG_01984	2.08e-200	554.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3WJDK@541000|Ruminococcaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
NMLHFLOH_02597	1232453.BAIF02000118_gene4522	2.71e-161	489.0	COG5434@1|root,COG5434@2|Bacteria,1TSA5@1239|Firmicutes,24AP9@186801|Clostridia	186801|Clostridia	M	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
NMLHFLOH_02598	411471.SUBVAR_04183	7.67e-80	249.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,3WK1G@541000|Ruminococcaceae	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
NMLHFLOH_02599	411462.DORLON_01003	7.1e-139	407.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27V29@189330|Dorea	186801|Clostridia	P	COG COG3839 ABC-type sugar transport systems, ATPase components	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NMLHFLOH_02600	411902.CLOBOL_04500	4.44e-165	466.0	COG1175@1|root,COG1175@2|Bacteria,1TSIQ@1239|Firmicutes,25C4Z@186801|Clostridia,21Z1S@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
NMLHFLOH_02601	1304866.K413DRAFT_3649	2.38e-155	443.0	COG0395@1|root,COG0395@2|Bacteria,1TR0I@1239|Firmicutes,24AZD@186801|Clostridia,36FB4@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
NMLHFLOH_02602	457421.CBFG_02629	7.04e-237	662.0	COG1653@1|root,COG1653@2|Bacteria,1TS64@1239|Firmicutes,249GC@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
NMLHFLOH_02603	457412.RSAG_01983	9.8e-179	497.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3WIKJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NMLHFLOH_02604	1121115.AXVN01000066_gene3231	0.0	972.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
NMLHFLOH_02605	1121115.AXVN01000066_gene3230	0.0	1252.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYZH@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NMLHFLOH_02606	457412.RSAG_01980	0.0	1207.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NMLHFLOH_02607	1121115.AXVN01000066_gene3228	4.97e-220	607.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NMLHFLOH_02608	1121115.AXVN01000066_gene3227	1.18e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NMLHFLOH_02609	457412.RSAG_01977	0.0	1583.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3WSNS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NMLHFLOH_02610	457412.RSAG_01976	8.73e-154	432.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
NMLHFLOH_02611	1121115.AXVN01000066_gene3224	9.9e-126	357.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NMLHFLOH_02612	1121115.AXVN01000066_gene3223	1.05e-102	296.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NMLHFLOH_02613	457412.RSAG_01973	1.6e-161	453.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NMLHFLOH_02614	457412.RSAG_01972	2.56e-99	288.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
NMLHFLOH_02615	1121115.AXVN01000066_gene3220	1.62e-225	620.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NMLHFLOH_02616	1121115.AXVN01000066_gene3219	1.12e-246	677.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NMLHFLOH_02617	1121115.AXVN01000066_gene3218	8.06e-165	461.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
NMLHFLOH_02618	1121115.AXVN01000146_gene773	2.48e-115	330.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NMLHFLOH_02619	457412.RSAG_02198	1.36e-136	386.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NMLHFLOH_02620	1121115.AXVN01000146_gene771	2.72e-283	773.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NMLHFLOH_02621	1121115.AXVN01000146_gene770	7.16e-132	373.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NMLHFLOH_02622	1121115.AXVN01000198_gene2447	6.29e-71	213.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NMLHFLOH_02623	1121115.AXVN01000198_gene2446	1.69e-33	115.0	2FGU2@1|root,348PD@2|Bacteria,1VZBU@1239|Firmicutes,252UE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02624	457412.RSAG_03402	0.0	1074.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3WH01@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NMLHFLOH_02625	1121115.AXVN01000106_gene671	0.0	1024.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
NMLHFLOH_02626	1121115.AXVN01000106_gene670	9.56e-267	729.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
NMLHFLOH_02627	457412.RSAG_03399	1.28e-198	551.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3WK8B@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
NMLHFLOH_02628	457412.RSAG_03398	0.0	2993.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,1VE3U@1239|Firmicutes,24KU9@186801|Clostridia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02629	457412.RSAG_03397	4.83e-92	270.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3WMFG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NMLHFLOH_02630	1121115.AXVN01000128_gene272	7.64e-219	602.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
NMLHFLOH_02631	457412.RSAG_03395	1.56e-283	772.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia,3WHAA@541000|Ruminococcaceae	186801|Clostridia	E	Porphyromonas-type peptidyl-arginine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
NMLHFLOH_02632	457412.RSAG_03394	2.5e-283	772.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NMLHFLOH_02633	457412.RSAG_03393	5.82e-309	842.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3WGMN@541000|Ruminococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NMLHFLOH_02634	1121115.AXVN01000128_gene276	9.27e-217	597.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3XZ5Q@572511|Blautia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
NMLHFLOH_02635	457412.RSAG_03391	0.0	948.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WGP2@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NMLHFLOH_02636	457412.RSAG_03390	0.0	1102.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NMLHFLOH_02637	1121115.AXVN01000030_gene3606	0.0	930.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,3Y0Z4@572511|Blautia	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
NMLHFLOH_02638	457412.RSAG_03388	4.63e-225	620.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3WKDZ@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_02639	1121115.AXVN01000030_gene3608	0.0	984.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NMLHFLOH_02640	457412.RSAG_03386	0.0	1018.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
NMLHFLOH_02643	97139.C824_00247	1.01e-74	238.0	COG0860@1|root,COG0860@2|Bacteria,1V60F@1239|Firmicutes,24J0F@186801|Clostridia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3
NMLHFLOH_02644	742733.HMPREF9469_05010	1.99e-42	140.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,220T9@1506553|Lachnoclostridium	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
NMLHFLOH_02645	658655.HMPREF0988_02547	6.27e-48	154.0	2E97K@1|root,333G3@2|Bacteria,1VI68@1239|Firmicutes,24QE0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02646	411460.RUMTOR_02099	6.71e-70	221.0	2DPQ8@1|root,332YA@2|Bacteria,1VEXS@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02647	411460.RUMTOR_02097	3.3e-81	253.0	2CA4H@1|root,3342S@2|Bacteria,1VUT9@1239|Firmicutes,250KP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02648	411460.RUMTOR_02096	5.15e-162	462.0	2BPU9@1|root,32IMR@2|Bacteria,1VA5U@1239|Firmicutes,24P81@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_Gp37
NMLHFLOH_02649	411462.DORLON_00776	8.36e-113	332.0	2AN2N@1|root,31D08@2|Bacteria,1V8DI@1239|Firmicutes,24MA8@186801|Clostridia,27WE8@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02650	742765.HMPREF9457_02136	9.23e-106	351.0	COG1511@1|root,COG5412@1|root,COG1511@2|Bacteria,COG5412@2|Bacteria,1TPR1@1239|Firmicutes	1239|Firmicutes	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
NMLHFLOH_02651	658655.HMPREF0988_02553	7.64e-80	243.0	2DJHU@1|root,32UD1@2|Bacteria,1V9ZS@1239|Firmicutes,24ECK@186801|Clostridia,27Q6V@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage Gp15 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Gp15
NMLHFLOH_02652	1235792.C808_05374	5.27e-39	134.0	2DQQR@1|root,3384M@2|Bacteria,1VF7Z@1239|Firmicutes,24U07@186801|Clostridia,27SAE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02653	1235792.C808_05373	6.58e-72	221.0	2DJKE@1|root,30GPD@2|Bacteria,1UGDJ@1239|Firmicutes,25NT7@186801|Clostridia,27RTT@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02654	411470.RUMGNA_02223	1.05e-77	233.0	2D8VZ@1|root,32TS2@2|Bacteria,1VA1V@1239|Firmicutes,24JYY@186801|Clostridia,3Y222@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Minor_capsid_3
NMLHFLOH_02655	658655.HMPREF0988_02557	7.11e-78	233.0	2C38D@1|root,31M9W@2|Bacteria,1V6Q7@1239|Firmicutes,24MA6@186801|Clostridia,27S52@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Minor_capsid_2
NMLHFLOH_02656	411470.RUMGNA_02221	1.32e-60	187.0	2EK0U@1|root,33DRC@2|Bacteria,1VP0F@1239|Firmicutes,24UVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02658	658655.HMPREF0988_02560	3.66e-175	491.0	2CGZW@1|root,2Z7Z5@2|Bacteria,1UVRJ@1239|Firmicutes,24AW4@186801|Clostridia,27RGQ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02659	742765.HMPREF9457_02126	6.15e-71	220.0	2DNUY@1|root,32ZA9@2|Bacteria,1VEH6@1239|Firmicutes,24QP4@186801|Clostridia	186801|Clostridia	S	COG NOG36366 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GP20
NMLHFLOH_02660	469618.FVAG_01307	8.79e-37	125.0	2EI5A@1|root,32Z4A@2|Bacteria,37CGN@32066|Fusobacteria	32066|Fusobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02662	658655.HMPREF0988_02563	9.46e-227	647.0	COG2369@1|root,COG2369@2|Bacteria,1UZ30@1239|Firmicutes,24D0A@186801|Clostridia,27J8I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage minor capsid protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Ntox50,Phage_min_cap2
NMLHFLOH_02663	658655.HMPREF0988_02564	5.59e-260	720.0	2BX0Z@1|root,2Z88Q@2|Bacteria,1UYMH@1239|Firmicutes,249U4@186801|Clostridia,27N4C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
NMLHFLOH_02664	411470.RUMGNA_02211	1.36e-276	761.0	COG1783@1|root,COG1783@2|Bacteria,1TT2C@1239|Firmicutes,24A7T@186801|Clostridia,3XZFV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_3,Terminase_6
NMLHFLOH_02665	742723.HMPREF9477_00912	5.18e-59	187.0	2DXIA@1|root,3454T@2|Bacteria,1VZDV@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	KGG
NMLHFLOH_02669	742765.HMPREF9457_02116	5.79e-52	169.0	2CYQ8@1|root,32T4K@2|Bacteria,1VBA3@1239|Firmicutes,24QBA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02673	742723.HMPREF9477_00922	3.6e-16	72.4	2980J@1|root,2ZV6N@2|Bacteria,1W4XP@1239|Firmicutes,256XZ@186801|Clostridia,27QNV@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02674	469596.HMPREF9488_02297	6.65e-14	71.6	28KZF@1|root,2ZAER@2|Bacteria,1UZ1D@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02675	658655.HMPREF0988_00878	7.11e-183	509.0	COG0863@1|root,COG0863@2|Bacteria,1TS56@1239|Firmicutes,249AU@186801|Clostridia	186801|Clostridia	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
NMLHFLOH_02679	665950.HMPREF1025_02545	1.97e-90	273.0	COG0863@1|root,COG0863@2|Bacteria,1VRVB@1239|Firmicutes,24GNY@186801|Clostridia,27PFY@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
NMLHFLOH_02681	645991.Sgly_0315	3.72e-18	84.0	COG5164@1|root,COG5164@2|Bacteria,1VBJS@1239|Firmicutes,24HVC@186801|Clostridia	186801|Clostridia	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02682	742740.HMPREF9474_03117	1.34e-60	199.0	2DMT9@1|root,32TI5@2|Bacteria,1VCAH@1239|Firmicutes,24N04@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02683	1235790.C805_00029	8.29e-40	136.0	COG4570@1|root,COG4570@2|Bacteria,1VFJ9@1239|Firmicutes,24NSB@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC	-	-	-	-	-	-	-	-	-	-	-	-	RusA
NMLHFLOH_02684	718252.FP2_01040	6.1e-11	65.5	2CBC9@1|root,30TPK@2|Bacteria,1V69K@1239|Firmicutes,24T0Z@186801|Clostridia,3WP4T@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02685	1289595.M1Q0X6_9VIRU	1.64e-42	149.0	4QBFR@10239|Viruses	10239|Viruses	S	ERF superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02697	1121115.AXVN01000084_gene1825	0.0	1812.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1UVF4@1239|Firmicutes,25KH5@186801|Clostridia,3Y235@572511|Blautia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NMLHFLOH_02698	1121115.AXVN01000084_gene1826	9.55e-88	258.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,2502W@186801|Clostridia,3Y24M@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02699	1121115.AXVN01000084_gene1827	0.0	1229.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1V7U3@1239|Firmicutes,24G0F@186801|Clostridia,3Y202@572511|Blautia	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NMLHFLOH_02700	1121115.AXVN01000084_gene1828	1.36e-186	523.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3XZED@572511|Blautia	186801|Clostridia	M	COG COG1464 ABC-type metal ion transport system, periplasmic component surface antigen	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
NMLHFLOH_02701	1121115.AXVN01000084_gene1829	2.63e-135	385.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3XYKJ@572511|Blautia	186801|Clostridia	P	COG COG2011 ABC-type metal ion transport system, permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
NMLHFLOH_02702	1121115.AXVN01000084_gene1830	1.52e-241	665.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3XZSW@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
NMLHFLOH_02703	457412.RSAG_02892	2.19e-56	175.0	2FAAA@1|root,342IX@2|Bacteria,1VY2R@1239|Firmicutes,251XQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02704	1121115.AXVN01000084_gene1832	2.04e-31	110.0	2CJV5@1|root,34BTB@2|Bacteria,1VZ3R@1239|Firmicutes,252Y4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02705	1121115.AXVN01000084_gene1833	2.13e-167	468.0	2EXDX@1|root,33QQG@2|Bacteria,1VTSR@1239|Firmicutes,24YUS@186801|Clostridia,3Y1G7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02706	457412.RSAG_02887	0.0	2499.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
NMLHFLOH_02707	1121115.AXVN01000084_gene1835	2.59e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_02708	1121115.AXVN01000084_gene1836	4.88e-198	548.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NMLHFLOH_02709	1121115.AXVN01000046_gene2947	3.88e-73	219.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NMLHFLOH_02710	1121115.AXVN01000046_gene2948	7.08e-49	155.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02711	1121115.AXVN01000046_gene2949	4.41e-131	372.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NMLHFLOH_02712	1121115.AXVN01000046_gene2950	0.0	886.0	COG4213@1|root,COG4213@2|Bacteria,1VR5M@1239|Firmicutes,24ZY3@186801|Clostridia,3Y037@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NMLHFLOH_02713	1121115.AXVN01000046_gene2951	7.42e-133	378.0	COG2378@1|root,COG2378@2|Bacteria,1UH6Q@1239|Firmicutes,2504G@186801|Clostridia,3Y0EB@572511|Blautia	186801|Clostridia	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02714	457412.RSAG_02878	9.84e-180	499.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WHHU@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
NMLHFLOH_02715	457412.RSAG_02877	0.0	898.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
NMLHFLOH_02716	457412.RSAG_02876	4.99e-221	608.0	COG0584@1|root,COG0584@2|Bacteria,1TUUB@1239|Firmicutes,259V0@186801|Clostridia,3WQRJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02717	1121115.AXVN01000046_gene2955	1.28e-115	332.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NMLHFLOH_02718	457412.RSAG_02873	5.58e-221	610.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NMLHFLOH_02719	457412.RSAG_02872	5.13e-138	390.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NMLHFLOH_02720	1121115.AXVN01000025_gene947	2.17e-93	272.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,3Y09T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NMLHFLOH_02721	1121115.AXVN01000025_gene946	0.0	1071.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
NMLHFLOH_02722	457412.RSAG_00215	4.18e-118	338.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NMLHFLOH_02723	457412.RSAG_00216	6.63e-162	456.0	29XH2@1|root,30J7P@2|Bacteria,1VSYJ@1239|Firmicutes,259SM@186801|Clostridia,3WQM3@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02724	457412.RSAG_00217	1.43e-294	802.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3WRJG@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_02725	457412.RSAG_00218	9.51e-155	434.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
NMLHFLOH_02726	1121115.AXVN01000017_gene232	1.42e-40	151.0	COG5492@1|root,COG5492@2|Bacteria,1TT7E@1239|Firmicutes,24J1K@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF5057)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5057
NMLHFLOH_02728	457412.RSAG_00222	7e-272	741.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3WHS1@541000|Ruminococcaceae	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02729	457412.RSAG_04727	1.41e-114	328.0	2DXFQ@1|root,344TK@2|Bacteria,1TV4T@1239|Firmicutes,259G5@186801|Clostridia,3WQ46@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02730	457412.RSAG_00225	3.71e-198	549.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3WIRH@541000|Ruminococcaceae	186801|Clostridia	K	CAT RNA binding domain	bglG	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
NMLHFLOH_02731	457412.RSAG_00226	0.0	1420.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WGH8@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	ptsG	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NMLHFLOH_02732	457412.RSAG_00227	0.0	1296.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
NMLHFLOH_02733	457412.RSAG_00228	0.0	1047.0	COG0791@1|root,COG0791@2|Bacteria,1UVPP@1239|Firmicutes,25KKC@186801|Clostridia,3WQIY@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
NMLHFLOH_02734	457412.RSAG_00229	6.26e-143	402.0	2ESIJ@1|root,33K39@2|Bacteria,1VP26@1239|Firmicutes,25HRK@186801|Clostridia,3WMIB@541000|Ruminococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NMLHFLOH_02735	457412.RSAG_00230	2.99e-49	156.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes,24R89@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02736	1121115.AXVN01000017_gene248	4.45e-133	377.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_02737	457412.RSAG_00232	4.85e-231	635.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3WGY0@541000|Ruminococcaceae	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
NMLHFLOH_02738	457412.RSAG_04728	0.0	1269.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NMLHFLOH_02739	457412.RSAG_00235	5.53e-246	681.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NMLHFLOH_02740	457412.RSAG_00236	2.63e-210	582.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NMLHFLOH_02742	1121115.AXVN01000088_gene4050	6.34e-297	809.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NMLHFLOH_02743	1121115.AXVN01000088_gene4049	0.0	910.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
NMLHFLOH_02744	457412.RSAG_03463	0.0	1009.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH71@541000|Ruminococcaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
NMLHFLOH_02745	1121115.AXVN01000088_gene4046	4.48e-139	403.0	2ECV2@1|root,336SH@2|Bacteria,1VFTD@1239|Firmicutes,24WJ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02746	457412.RSAG_03465	3.39e-182	507.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24XQ2@186801|Clostridia,3WJKU@541000|Ruminococcaceae	186801|Clostridia	V	Vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,Transglut_core
NMLHFLOH_02747	1121115.AXVN01000088_gene4044	5.88e-154	432.0	2EYGG@1|root,33RQD@2|Bacteria,1VRY6@1239|Firmicutes,24XIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02748	1121115.AXVN01000088_gene4043	1.18e-183	516.0	COG5263@1|root,COG5263@2|Bacteria,1VQWH@1239|Firmicutes,24ZPP@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NMLHFLOH_02749	1121115.AXVN01000088_gene4041	6.65e-153	429.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3Y0DJ@572511|Blautia	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NMLHFLOH_02750	1121115.AXVN01000088_gene4040	4.76e-78	233.0	COG2198@1|root,COG2198@2|Bacteria,1TUB6@1239|Firmicutes,257TB@186801|Clostridia,3Y0UT@572511|Blautia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NMLHFLOH_02751	1121115.AXVN01000088_gene4039	1.97e-295	814.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NMLHFLOH_02752	457412.RSAG_03471	0.0	1590.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
NMLHFLOH_02753	1121115.AXVN01000088_gene4037	4.8e-139	392.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NMLHFLOH_02754	457412.RSAG_03473	0.0	1030.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
NMLHFLOH_02755	1121115.AXVN01000130_gene182	5.09e-302	823.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3Y1H7@572511|Blautia	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NMLHFLOH_02756	457412.RSAG_03475	2.28e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3WIGV@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NMLHFLOH_02757	457412.RSAG_03476	4.04e-304	828.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NMLHFLOH_02758	1121115.AXVN01000130_gene185	7.39e-113	323.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NMLHFLOH_02759	1121115.AXVN01000130_gene186	6.35e-300	816.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
NMLHFLOH_02760	457412.RSAG_03479	1.94e-104	301.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
NMLHFLOH_02761	1121115.AXVN01000130_gene188	2.82e-197	546.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NMLHFLOH_02762	1121115.AXVN01000130_gene189	5.34e-89	261.0	COG5361@1|root,COG5361@2|Bacteria,1U2H3@1239|Firmicutes,24F4F@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
NMLHFLOH_02763	1280698.AUJS01000042_gene3268	6.83e-76	226.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,25NNG@186801|Clostridia,27X9B@189330|Dorea	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NMLHFLOH_02764	411459.RUMOBE_01921	7.18e-79	234.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NMLHFLOH_02765	457412.RSAG_00878	0.0	1938.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia,3WHD4@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
NMLHFLOH_02766	457412.RSAG_00879	1.74e-179	514.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02767	457412.RSAG_00880	0.0	1114.0	COG1961@1|root,COG1961@2|Bacteria,1TWK9@1239|Firmicutes,24C30@186801|Clostridia,3WHD6@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_02769	457412.RSAG_00882	5.05e-184	511.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,3WMNU@541000|Ruminococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
NMLHFLOH_02770	457412.RSAG_00883	0.0	933.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
NMLHFLOH_02771	457412.RSAG_00884	1.63e-52	165.0	2E714@1|root,331JV@2|Bacteria,1VQIV@1239|Firmicutes,251NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02772	457412.RSAG_00885	9.08e-202	559.0	COG1737@1|root,COG1737@2|Bacteria,1VBUB@1239|Firmicutes,24MTV@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NMLHFLOH_02773	457412.RSAG_00886	3.03e-278	760.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
NMLHFLOH_02775	457412.RSAG_00888	2.29e-179	500.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
NMLHFLOH_02776	457412.RSAG_03422	5.89e-220	610.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,3WN05@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NMLHFLOH_02777	457412.RSAG_00891	2.81e-181	504.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
NMLHFLOH_02778	457412.RSAG_00892	4.72e-107	308.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
NMLHFLOH_02779	457412.RSAG_00893	6.87e-24	92.0	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02780	457412.RSAG_00894	8.94e-100	289.0	COG2198@1|root,COG3437@1|root,COG2198@2|Bacteria,COG3437@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NMLHFLOH_02781	457412.RSAG_00895	0.0	1815.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NMLHFLOH_02785	1121115.AXVN01000115_gene2458	1.19e-194	540.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3Y01U@572511|Blautia	186801|Clostridia	D	COG COG2385 Sporulation protein and related proteins	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NMLHFLOH_02786	1121115.AXVN01000115_gene2457	7.73e-201	557.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NMLHFLOH_02787	1121115.AXVN01000115_gene2456	7.18e-234	644.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ29@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NMLHFLOH_02788	457412.RSAG_03206	0.0	1218.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3WG8J@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
NMLHFLOH_02789	457412.RSAG_03205	0.0	1003.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WGUV@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NMLHFLOH_02790	457412.RSAG_03204	1.29e-53	167.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3WKVK@541000|Ruminococcaceae	186801|Clostridia	L	GIY-YIG catalytic domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
NMLHFLOH_02791	457412.RSAG_03203	3.78e-182	512.0	COG5263@1|root,COG5263@2|Bacteria,1UJWN@1239|Firmicutes,25FCE@186801|Clostridia,3WKY6@541000|Ruminococcaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
NMLHFLOH_02792	1121115.AXVN01000115_gene2450	3.1e-154	433.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
NMLHFLOH_02793	457412.RSAG_03201	9.44e-189	524.0	COG1192@1|root,COG1192@2|Bacteria,1UPGE@1239|Firmicutes,24A5R@186801|Clostridia,3WPYK@541000|Ruminococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HTH_3
NMLHFLOH_02794	1121115.AXVN01000031_gene322	1.24e-31	110.0	2CA4Q@1|root,349NE@2|Bacteria,1VYK2@1239|Firmicutes,253VZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02795	457412.RSAG_03199	9.48e-237	651.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia,3WK12@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NMLHFLOH_02796	457412.RSAG_03198	0.0	1402.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NMLHFLOH_02797	457412.RSAG_03197	0.0	2211.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
NMLHFLOH_02798	457412.RSAG_03196	8.3e-123	350.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3WITH@541000|Ruminococcaceae	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NMLHFLOH_02799	1121115.AXVN01000031_gene333	6.73e-293	799.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3XZND@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NMLHFLOH_02800	1121115.AXVN01000031_gene334	0.0	958.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3XZKK@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
NMLHFLOH_02802	457412.RSAG_03156	2.87e-90	266.0	28RTR@1|root,2ZE63@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02803	1121115.AXVN01000055_gene1920	0.0	1642.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3XZEY@572511|Blautia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NMLHFLOH_02804	457412.RSAG_03158	0.0	2165.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
NMLHFLOH_02805	457412.RSAG_03160	3.99e-297	810.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NMLHFLOH_02806	1121115.AXVN01000055_gene1916	3.45e-240	659.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
NMLHFLOH_02807	1121115.AXVN01000055_gene1915	8.81e-264	723.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
NMLHFLOH_02808	1121115.AXVN01000055_gene1914	1.05e-51	163.0	2CDIT@1|root,338T3@2|Bacteria,1VJ1M@1239|Firmicutes,24SF4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NMLHFLOH_02809	1121115.AXVN01000055_gene1913	0.0	1110.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NMLHFLOH_02810	1121115.AXVN01000055_gene1912	4.87e-203	563.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NMLHFLOH_02811	1121115.AXVN01000055_gene1911	6.44e-239	657.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NMLHFLOH_02812	1121115.AXVN01000055_gene1910	1.88e-220	607.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y14P@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NMLHFLOH_02813	1121115.AXVN01000055_gene1909	7.27e-242	664.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NMLHFLOH_02814	457412.RSAG_03169	0.0	1035.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3WJCS@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NMLHFLOH_02815	457412.RSAG_03170	0.0	1318.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
NMLHFLOH_02816	1121115.AXVN01000092_gene78	1.08e-209	582.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02817	1121115.AXVN01000092_gene77	0.0	1805.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3XYMW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NMLHFLOH_02818	411459.RUMOBE_01997	3.19e-139	454.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,3XYNF@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
NMLHFLOH_02819	411459.RUMOBE_01996	4.76e-73	226.0	COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,24JQ7@186801|Clostridia,3Y03H@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NMLHFLOH_02820	1121115.AXVN01000092_gene76	5.11e-107	309.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NMLHFLOH_02821	1121115.AXVN01000092_gene75	0.0	1096.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NMLHFLOH_02822	1121115.AXVN01000092_gene74	7.77e-159	445.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3XYH5@572511|Blautia	186801|Clostridia	T	positive response regulator for pho regulon	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_02823	457412.RSAG_01993	1.86e-316	862.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
NMLHFLOH_02824	1121115.AXVN01000092_gene72	5.81e-313	852.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02825	1121115.AXVN01000092_gene71	5.28e-221	609.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_02826	1121115.AXVN01000092_gene70	3.23e-310	844.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02827	1121115.AXVN01000092_gene69	1.35e-211	586.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_02828	457412.RSAG_01988	1.35e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WN1I@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_02829	457412.RSAG_02180	5.22e-101	312.0	COG1520@1|root,COG1520@2|Bacteria,1UKI6@1239|Firmicutes,25FXQ@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02830	457412.RSAG_02181	8.81e-90	262.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
NMLHFLOH_02831	457412.RSAG_02182	1.56e-166	466.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3WHMG@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_02832	1121115.AXVN01000024_gene293	5.75e-302	825.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3Y0QZ@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_02833	1121115.AXVN01000024_gene292	2.1e-289	790.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NMLHFLOH_02834	1121115.AXVN01000024_gene291	1.86e-213	589.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
NMLHFLOH_02835	457412.RSAG_02186	9.59e-287	784.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NMLHFLOH_02836	457412.RSAG_02187	4.83e-256	701.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NMLHFLOH_02837	1121115.AXVN01000024_gene288	2.07e-302	823.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
NMLHFLOH_02838	1121115.AXVN01000024_gene287	5.34e-81	240.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24WC7@186801|Clostridia	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NMLHFLOH_02839	457412.RSAG_02190	4.8e-240	664.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WH44@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NMLHFLOH_02840	1121115.AXVN01000024_gene284	1.22e-310	846.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NMLHFLOH_02841	457412.RSAG_02192	2.76e-305	835.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NMLHFLOH_02842	457412.RSAG_02193	5.11e-214	592.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NMLHFLOH_02843	457412.RSAG_02194	1.7e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NMLHFLOH_02844	1121115.AXVN01000146_gene775	7.72e-165	461.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3Y00D@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NMLHFLOH_02845	457412.RSAG_02196	1.46e-163	459.0	COG0568@1|root,COG0568@2|Bacteria,1W6ZB@1239|Firmicutes,25MJD@186801|Clostridia,3WQKW@541000|Ruminococcaceae	186801|Clostridia	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02853	1121115.AXVN01000061_gene495	2.89e-101	300.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_02854	1121115.AXVN01000061_gene496	2.71e-177	496.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_02855	1121115.AXVN01000061_gene497	0.0	1649.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3Y07X@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NMLHFLOH_02856	1121115.AXVN01000061_gene498	5.94e-307	834.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
NMLHFLOH_02857	457412.RSAG_00704	6.22e-207	571.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NMLHFLOH_02858	457412.RSAG_00703	0.0	1481.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3WHG2@541000|Ruminococcaceae	186801|Clostridia	S	Lacto-N-biose phosphorylase C-terminal domain	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
NMLHFLOH_02859	457412.RSAG_00702	1.29e-259	711.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
NMLHFLOH_02860	457412.RSAG_00701	0.0	972.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WNM6@541000|Ruminococcaceae	186801|Clostridia	O	PrkA AAA domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
NMLHFLOH_02861	457412.RSAG_00700	6.35e-278	759.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WG7W@541000|Ruminococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
NMLHFLOH_02862	457412.RSAG_00699	1.83e-149	421.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
NMLHFLOH_02863	457412.RSAG_00698	9.66e-292	796.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WGA9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
NMLHFLOH_02864	457412.RSAG_00697	2.6e-106	306.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3WINK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
NMLHFLOH_02865	457412.RSAG_00696	5.39e-250	686.0	COG0564@1|root,COG0564@2|Bacteria,1VS66@1239|Firmicutes,25M7T@186801|Clostridia,3WP3U@541000|Ruminococcaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
NMLHFLOH_02866	457412.RSAG_00695	2.11e-221	610.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,249UK@186801|Clostridia,3WGSB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
NMLHFLOH_02867	1121115.AXVN01000043_gene3367	4.8e-70	225.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3XYJY@572511|Blautia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
NMLHFLOH_02868	1121115.AXVN01000002_gene1383	2.6e-81	240.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
NMLHFLOH_02869	1121115.AXVN01000002_gene1382	3.22e-140	395.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NMLHFLOH_02870	1121115.AXVN01000002_gene1381	6.73e-303	827.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
NMLHFLOH_02871	1121115.AXVN01000002_gene1380	1.76e-147	416.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
NMLHFLOH_02872	1121115.AXVN01000002_gene1379	4.36e-263	721.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
NMLHFLOH_02873	457412.RSAG_00015	2.14e-127	362.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,3WIFA@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
NMLHFLOH_02874	1121115.AXVN01000002_gene1377	6.57e-107	310.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NMLHFLOH_02875	457412.RSAG_00013	1.67e-249	684.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3WH5D@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NMLHFLOH_02876	457412.RSAG_00012	1.83e-150	423.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24KKS@186801|Clostridia,3WM0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02877	457412.RSAG_00011	0.0	1295.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3WGM7@541000|Ruminococcaceae	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NMLHFLOH_02878	457412.RSAG_00010	4.3e-189	525.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3WNY9@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NMLHFLOH_02879	1121115.AXVN01000002_gene1372	0.0	954.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_02880	457412.RSAG_00008	6.8e-221	609.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WIGE@541000|Ruminococcaceae	186801|Clostridia	S	sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
NMLHFLOH_02881	1121115.AXVN01000002_gene1370	2.51e-94	281.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02882	1121115.AXVN01000002_gene1369	1.66e-111	320.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NMLHFLOH_02883	1121115.AXVN01000002_gene1368	4.62e-125	356.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
NMLHFLOH_02884	1121115.AXVN01000002_gene1367	1.27e-90	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NMLHFLOH_02885	457412.RSAG_00003	2.31e-69	209.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
NMLHFLOH_02887	457412.RSAG_03136	2.37e-226	625.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NMLHFLOH_02888	457412.RSAG_04544	4.73e-32	130.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
NMLHFLOH_02889	457412.RSAG_03137	8.34e-229	630.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NMLHFLOH_02890	457412.RSAG_03138	1.63e-197	548.0	COG1047@1|root,COG1433@1|root,COG1047@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Nitro_FeMo-Co
NMLHFLOH_02891	457412.RSAG_03139	0.0	1576.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UK8D@1239|Firmicutes,25FQD@186801|Clostridia,3WJ22@541000|Ruminococcaceae	186801|Clostridia	N	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02893	457412.RSAG_04544	0.0	2684.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
NMLHFLOH_02894	1121115.AXVN01000091_gene2616	4.55e-33	122.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NMLHFLOH_02895	457412.RSAG_03142	1.59e-33	115.0	2E8E4@1|root,332SJ@2|Bacteria,1VHFW@1239|Firmicutes,24QN9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02896	457412.RSAG_03143	2.58e-132	375.0	COG4185@1|root,COG4185@2|Bacteria,1V42Y@1239|Firmicutes,24A28@186801|Clostridia,3WIQX@541000|Ruminococcaceae	186801|Clostridia	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
NMLHFLOH_02897	457412.RSAG_03144	0.0	905.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NMLHFLOH_02899	1121115.AXVN01000107_gene613	7.86e-132	374.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3Y0SC@572511|Blautia	186801|Clostridia	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
NMLHFLOH_02900	1121115.AXVN01000107_gene612	1.11e-144	410.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3XZZP@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NMLHFLOH_02901	457412.RSAG_01700	2.97e-304	833.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WH4B@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NMLHFLOH_02902	33035.JPJF01000035_gene3475	0.0	1121.0	COG3345@1|root,COG3345@2|Bacteria,1TSZB@1239|Firmicutes,247VV@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
NMLHFLOH_02903	742733.HMPREF9469_03114	8.05e-144	412.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,2247R@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NMLHFLOH_02904	33035.JPJF01000035_gene3477	1.72e-178	501.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NMLHFLOH_02905	33035.JPJF01000035_gene3478	3.15e-233	650.0	COG1653@1|root,COG1653@2|Bacteria,1UZFS@1239|Firmicutes	1239|Firmicutes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02906	33035.JPJF01000035_gene3479	5.38e-166	487.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3XZ1E@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NMLHFLOH_02907	33035.JPJF01000035_gene3480	9.39e-182	534.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KCW@186801|Clostridia,3Y11X@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NMLHFLOH_02908	742733.HMPREF9469_03109	1.02e-97	307.0	COG1653@1|root,COG1653@2|Bacteria,1TPBS@1239|Firmicutes,24K16@186801|Clostridia,22139@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NMLHFLOH_02909	478749.BRYFOR_05763	1.69e-107	322.0	COG2207@1|root,COG2207@2|Bacteria,1UYG6@1239|Firmicutes,24JEP@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_02910	478749.BRYFOR_05765	0.0	907.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
NMLHFLOH_02911	457412.RSAG_01701	3.17e-49	167.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3WGU0@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
NMLHFLOH_02912	457412.RSAG_00564	4.39e-66	200.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	xre	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NMLHFLOH_02913	1121115.AXVN01000083_gene2460	1.34e-31	110.0	2FEN0@1|root,346MC@2|Bacteria,1VZFX@1239|Firmicutes,2532H@186801|Clostridia,3Y1ZK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02914	457412.RSAG_00567	2.68e-84	248.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WJVE@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
NMLHFLOH_02915	457412.RSAG_00568	3.35e-73	219.0	296J0@1|root,2ZP02@2|Bacteria,1TTVX@1239|Firmicutes,25MY8@186801|Clostridia,3WM17@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC,RHH_1
NMLHFLOH_02916	457412.RSAG_00569	0.0	906.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3WH5V@541000|Ruminococcaceae	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NMLHFLOH_02917	411459.RUMOBE_00585	1.11e-96	281.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NMLHFLOH_02918	411459.RUMOBE_00586	7.88e-79	234.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
NMLHFLOH_02919	457412.RSAG_00587	0.0	1178.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3WKAT@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
NMLHFLOH_02920	457412.RSAG_00588	3.34e-307	836.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3WKA7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02921	411459.RUMOBE_00589	4.91e-287	783.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3XZZK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02922	411459.RUMOBE_00590	0.0	1383.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3XZ30@572511|Blautia	186801|Clostridia	M	penicillin-binding protein 2'	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
NMLHFLOH_02923	1121115.AXVN01000003_gene1516	3.71e-53	166.0	2E255@1|root,32XC6@2|Bacteria,1VASU@1239|Firmicutes,25PWU@186801|Clostridia,3Y1UH@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
NMLHFLOH_02924	411459.RUMOBE_00600	7.38e-195	572.0	COG1669@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,3XYTM@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF3849,DUF4316,Peptidase_M78,YodL,zf-CHC2
NMLHFLOH_02925	411467.BACCAP_02259	8.63e-29	112.0	2DXV6@1|root,32V45@2|Bacteria,1VBYR@1239|Firmicutes,24P8R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02926	457412.RSAG_00594	6.27e-252	694.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
NMLHFLOH_02927	457412.RSAG_01012	9.18e-56	183.0	COG3385@1|root,COG3385@2|Bacteria,1TRKC@1239|Firmicutes,24EUB@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
NMLHFLOH_02929	411462.DORLON_01361	2.02e-130	372.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia	186801|Clostridia	I	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_02930	1121333.JMLH01000045_gene946	2.5e-122	358.0	COG4099@1|root,COG4099@2|Bacteria,1V5NZ@1239|Firmicutes	1239|Firmicutes	S	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
NMLHFLOH_02931	411463.EUBVEN_00911	2.02e-170	483.0	COG0667@1|root,COG0667@2|Bacteria,1TPIY@1239|Firmicutes,25B3Z@186801|Clostridia,25ZHN@186806|Eubacteriaceae	186801|Clostridia	C	Oxidoreductase, aldo keto reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NMLHFLOH_02932	1504823.CCMM01000013_gene2623	7.35e-27	106.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	mdaB2	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NMLHFLOH_02933	411463.EUBVEN_00912	8.52e-86	262.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,25WZH@186806|Eubacteriaceae	186801|Clostridia	C	COG COG0716 Flavodoxins	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NMLHFLOH_02934	641107.CDLVIII_0885	1.31e-210	588.0	COG1075@1|root,COG1075@2|Bacteria,1UK5W@1239|Firmicutes,24C0J@186801|Clostridia,36M5V@31979|Clostridiaceae	186801|Clostridia	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
NMLHFLOH_02935	641107.CDLVIII_0883	8.21e-74	229.0	COG0716@1|root,COG0716@2|Bacteria,1V7RZ@1239|Firmicutes	1239|Firmicutes	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NMLHFLOH_02936	657322.FPR_27310	1.25e-196	553.0	COG0657@1|root,COG0657@2|Bacteria,1UEU5@1239|Firmicutes,24BRQ@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NMLHFLOH_02937	1235798.C817_02673	1.18e-81	244.0	COG0655@1|root,COG0655@2|Bacteria,1V5J1@1239|Firmicutes,24SP5@186801|Clostridia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_02938	478749.BRYFOR_06737	1.51e-156	446.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,MerR_1
NMLHFLOH_02939	397291.C804_04713	1.1e-79	245.0	2969W@1|root,2ZTJV@2|Bacteria,1V4DZ@1239|Firmicutes,24HW0@186801|Clostridia,27MJM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
NMLHFLOH_02940	397291.C804_04699	1.46e-156	454.0	COG0657@1|root,COG4925@1|root,COG0657@2|Bacteria,COG4925@2|Bacteria,1U1GT@1239|Firmicutes,25KGS@186801|Clostridia,27Q30@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02941	1235798.C817_02670	1.19e-223	623.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27V0U@189330|Dorea	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NMLHFLOH_02942	411462.DORLON_01364	6.21e-151	432.0	COG0583@1|root,COG0583@2|Bacteria,1TQWY@1239|Firmicutes,249N9@186801|Clostridia,27WMV@189330|Dorea	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_02943	1280698.AUJS01000025_gene2242	3.05e-15	73.6	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,27WRQ@189330|Dorea	186801|Clostridia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NMLHFLOH_02944	411459.RUMOBE_00714	1.2e-192	533.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,3XZ96@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
NMLHFLOH_02945	1121115.AXVN01000003_gene1577	3.67e-56	177.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,3Y09P@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NMLHFLOH_02946	457412.RSAG_03283	4.67e-127	361.0	COG0778@1|root,COG0778@2|Bacteria,1V80D@1239|Firmicutes,24I9R@186801|Clostridia,3WRRJ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
NMLHFLOH_02947	457412.RSAG_03282	0.0	921.0	COG1376@1|root,COG1376@2|Bacteria,1W706@1239|Firmicutes,258MI@186801|Clostridia,3WN4E@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NMLHFLOH_02948	1121115.AXVN01000099_gene787	1.41e-207	573.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NMLHFLOH_02950	457412.RSAG_03280	0.0	1472.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3WGCV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain protein	tvaI	-	3.2.1.133,3.2.1.135,3.2.1.20,3.2.1.54	ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R02112,R03122,R06087,R06088,R11262	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH13,GH31	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
NMLHFLOH_02951	457412.RSAG_03279	0.0	1141.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3WG86@541000|Ruminococcaceae	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NMLHFLOH_02952	457412.RSAG_04578	3.04e-122	348.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NMLHFLOH_02953	457412.RSAG_03278	0.0	966.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NMLHFLOH_02954	457412.RSAG_03277	0.0	981.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NMLHFLOH_02955	457412.RSAG_03276	2.36e-47	153.0	COG2919@1|root,COG2919@2|Bacteria,1VX29@1239|Firmicutes,252JU@186801|Clostridia,3WMKM@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NMLHFLOH_02956	457412.RSAG_03275	1.19e-101	295.0	2EFTM@1|root,3095D@2|Bacteria,1U4G7@1239|Firmicutes,25JHX@186801|Clostridia,3WR8N@541000|Ruminococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
NMLHFLOH_02957	457412.RSAG_03274	8.11e-58	179.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
NMLHFLOH_02958	1121115.AXVN01000099_gene779	3.38e-46	149.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NMLHFLOH_02959	1121115.AXVN01000099_gene778	1.6e-55	174.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NMLHFLOH_02960	457412.RSAG_03271	4.65e-153	434.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3WJKX@541000|Ruminococcaceae	186801|Clostridia	S	Spore coat protein, CotS family	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
NMLHFLOH_02961	1121115.AXVN01000055_gene1906	1.94e-99	290.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NMLHFLOH_02962	457412.RSAG_03172	1.03e-240	661.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NMLHFLOH_02963	1121115.AXVN01000055_gene1904	2.46e-81	241.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02964	457412.RSAG_03174	1.84e-193	536.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NMLHFLOH_02965	1121115.AXVN01000055_gene1902	1.17e-245	674.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NMLHFLOH_02966	1121115.AXVN01000055_gene1901	1.41e-151	434.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NMLHFLOH_02967	1121115.AXVN01000055_gene1900	4.78e-90	265.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NMLHFLOH_02968	457412.RSAG_03178	1.82e-179	500.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3WIQ9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
NMLHFLOH_02969	457412.RSAG_03179	1.75e-148	418.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3WJQ0@541000|Ruminococcaceae	186801|Clostridia	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NMLHFLOH_02970	457412.RSAG_03180	0.0	892.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NMLHFLOH_02971	457412.RSAG_03181	1.65e-240	660.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NMLHFLOH_02972	457412.RSAG_03182	0.0	2280.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NMLHFLOH_02973	1121115.AXVN01000031_gene349	2.81e-194	539.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
NMLHFLOH_02974	1458462.JNLK01000001_gene2611	3.91e-60	206.0	COG0494@1|root,COG2110@1|root,COG5113@1|root,COG0494@2|Bacteria,COG2110@2|Bacteria,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,27NI1@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
NMLHFLOH_02976	1121115.AXVN01000077_gene2653	4.53e-96	279.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
NMLHFLOH_02977	457412.RSAG_00956	4.6e-170	476.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
NMLHFLOH_02978	457412.RSAG_00957	0.0	1880.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WGSH@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Oxidored_FMN,Pyr_redox_2
NMLHFLOH_02979	457412.RSAG_00958	0.0	926.0	COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,24C6R@186801|Clostridia,3WNTJ@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NMLHFLOH_02980	1121115.AXVN01000077_gene2649	1.76e-186	518.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3XZY2@572511|Blautia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
NMLHFLOH_02981	1121115.AXVN01000035_gene3825	8.96e-10	60.1	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3XZ2T@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NMLHFLOH_02982	1121115.AXVN01000077_gene2647	6.26e-92	268.0	COG0655@1|root,COG0655@2|Bacteria,1V26K@1239|Firmicutes,25NF4@186801|Clostridia,3Y0JQ@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_02983	1121115.AXVN01000077_gene2646	2.44e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3Y1N1@572511|Blautia	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
NMLHFLOH_02984	1121115.AXVN01000077_gene2645	2.24e-200	555.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3Y13Y@572511|Blautia	186801|Clostridia	H	Pantoate-beta-alanine ligase	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
NMLHFLOH_02985	1121115.AXVN01000077_gene2644	1.13e-87	258.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3Y1QS@572511|Blautia	186801|Clostridia	H	Aspartate decarboxylase	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
NMLHFLOH_02986	457412.RSAG_00693	1.72e-139	399.0	2E03H@1|root,333DZ@2|Bacteria,1VJ8Q@1239|Firmicutes,24RNP@186801|Clostridia,3WRYM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02987	457412.RSAG_00692	1.03e-73	221.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3WK00@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
NMLHFLOH_02988	457412.RSAG_00691	1.59e-241	664.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia,3WIPF@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
NMLHFLOH_02989	457412.RSAG_00690	1.35e-119	342.0	28P26@1|root,2ZBYA@2|Bacteria,1V1VU@1239|Firmicutes,24GBU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02990	457412.RSAG_00689	6.86e-108	311.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WMPN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
NMLHFLOH_02991	457412.RSAG_00688	2.9e-113	325.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3WJG3@541000|Ruminococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NMLHFLOH_02992	457412.RSAG_00687	1.41e-141	399.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WHRM@541000|Ruminococcaceae	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NMLHFLOH_02993	1121115.AXVN01000043_gene3375	4.84e-145	408.0	COG2227@1|root,COG2227@2|Bacteria,1V1MT@1239|Firmicutes,24FTN@186801|Clostridia,3Y29B@572511|Blautia	186801|Clostridia	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,NUDIX
NMLHFLOH_02994	1121115.AXVN01000043_gene3376	0.0	1457.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
NMLHFLOH_02995	457412.RSAG_00684	2.6e-14	70.5	28N02@1|root,2ZB6N@2|Bacteria,1UZ98@1239|Firmicutes,24FB2@186801|Clostridia,3WNNW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02996	457412.RSAG_00684	1.23e-150	428.0	28N02@1|root,2ZB6N@2|Bacteria,1UZ98@1239|Firmicutes,24FB2@186801|Clostridia,3WNNW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_02997	936574.HMPREF1508_0650	6.29e-237	671.0	COG1195@1|root,COG3593@1|root,COG1195@2|Bacteria,COG3593@2|Bacteria,1TVDV@1239|Firmicutes,25DHX@186801|Clostridia	186801|Clostridia	L	ATP-dependent endonuclease of the OLD family	-	-	-	ko:K07459	-	-	-	-	ko00000	-	-	-	AAA_15
NMLHFLOH_02998	936574.HMPREF1508_0649	1.12e-22	96.7	COG0210@1|root,COG0210@2|Bacteria,1W75Q@1239|Firmicutes,24SIM@186801|Clostridia	186801|Clostridia	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD-helicase
NMLHFLOH_02999	1121115.AXVN01000004_gene1976	0.0	899.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NMLHFLOH_03000	1121115.AXVN01000004_gene1975	7.54e-211	583.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3XZ0R@572511|Blautia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NMLHFLOH_03001	1121115.AXVN01000004_gene1974	0.0	1178.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3XZB2@572511|Blautia	186801|Clostridia	GT	Psort location CytoplasmicMembrane, score 10.00	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NMLHFLOH_03002	1121115.AXVN01000004_gene1973	4.05e-53	167.0	COG1925@1|root,COG1925@2|Bacteria,1VE7N@1239|Firmicutes,24Q2D@186801|Clostridia,3Y0JB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	ptsH	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NMLHFLOH_03003	1121115.AXVN01000004_gene1972	1.72e-163	459.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NMLHFLOH_03004	457412.RSAG_00403	3.6e-265	727.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NMLHFLOH_03005	1121115.AXVN01000004_gene1969	0.0	1775.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3XZKX@572511|Blautia	186801|Clostridia	L	Psort location	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
NMLHFLOH_03006	1121115.AXVN01000004_gene1968	9.01e-132	373.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3Y04A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
NMLHFLOH_03007	1121115.AXVN01000004_gene1967	1.39e-96	281.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NMLHFLOH_03008	457412.RSAG_02614	9.31e-97	281.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24JJP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03012	457412.RSAG_02619	5.12e-112	322.0	COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes	1239|Firmicutes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
NMLHFLOH_03013	457412.RSAG_02620	3.24e-221	610.0	2EZSX@1|root,33SXM@2|Bacteria,1VS9M@1239|Firmicutes,24XHD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03014	457412.RSAG_02621	3.6e-302	826.0	COG0642@1|root,COG0642@2|Bacteria,1UKI9@1239|Firmicutes,24XZM@186801|Clostridia,3WSRW@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NMLHFLOH_03015	457412.RSAG_02622	7.14e-167	466.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3WJ2Q@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NMLHFLOH_03016	457412.RSAG_02623	0.0	1073.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,3WIKQ@541000|Ruminococcaceae	186801|Clostridia	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
NMLHFLOH_03017	457412.RSAG_02624	4.04e-103	298.0	COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,24MTF@186801|Clostridia,3WKUD@541000|Ruminococcaceae	186801|Clostridia	T	TspO MBR family protein	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
NMLHFLOH_03019	457412.RSAG_02626	8.64e-125	355.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3WJT2@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NMLHFLOH_03020	457412.RSAG_01324	2.15e-300	819.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
NMLHFLOH_03021	457412.RSAG_02445	8.56e-68	204.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,25CMX@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
NMLHFLOH_03022	457412.RSAG_02444	5.1e-219	604.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,3WI4X@541000|Ruminococcaceae	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03023	1121115.AXVN01000065_gene675	4.34e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NMLHFLOH_03024	457412.RSAG_01493	1.32e-228	631.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NMLHFLOH_03025	457412.RSAG_01494	6.05e-212	591.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NMLHFLOH_03026	457412.RSAG_01496	5.9e-298	812.0	2CF3U@1|root,33TFS@2|Bacteria,1VS98@1239|Firmicutes,24YVZ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03027	457412.RSAG_01497	2.62e-200	554.0	COG0631@1|root,COG0631@2|Bacteria,1VXKJ@1239|Firmicutes,2522X@186801|Clostridia,3WK7B@541000|Ruminococcaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C,PP2C_2
NMLHFLOH_03028	457412.RSAG_01498	0.0	1173.0	COG0515@1|root,COG0515@2|Bacteria,1V2ZP@1239|Firmicutes,24G58@186801|Clostridia,3WIKP@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5050,PASTA,Pkinase,SH3_3
NMLHFLOH_03029	457412.RSAG_01499	0.0	1649.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
NMLHFLOH_03030	1121115.AXVN01000065_gene680	8.86e-35	119.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03031	411489.CLOL250_01657	3.46e-78	233.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NMLHFLOH_03032	411489.CLOL250_01656	8.24e-265	734.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NMLHFLOH_03033	411489.CLOL250_01655	1.69e-51	162.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,36TY6@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NMLHFLOH_03034	411489.CLOL250_01654	1.03e-43	142.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,36T49@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03035	411489.CLOL250_01653	4.28e-231	637.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia,36UNR@31979|Clostridiaceae	186801|Clostridia	O	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
NMLHFLOH_03036	411489.CLOL250_01652	1.09e-291	796.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36E23@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NMLHFLOH_03037	411489.CLOL250_01651	6.69e-34	116.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,36PEI@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03038	411489.CLOL250_01650	4.27e-140	397.0	COG1396@1|root,COG1396@2|Bacteria,1TQ4Q@1239|Firmicutes,25FKR@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_03039	457412.RSAG_01489	3.22e-289	789.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NMLHFLOH_03040	457412.RSAG_01490	0.0	1409.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NMLHFLOH_03041	457412.RSAG_01491	6.62e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NMLHFLOH_03042	1121115.AXVN01000104_gene847	1.65e-216	600.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
NMLHFLOH_03043	1121115.AXVN01000104_gene846	0.0	1071.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3Y116@572511|Blautia	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NMLHFLOH_03044	1121115.AXVN01000104_gene845	7.3e-59	181.0	2C9HP@1|root,33Z9H@2|Bacteria,1W1CU@1239|Firmicutes,25441@186801|Clostridia,3Y0HT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03045	457412.RSAG_01508	4.25e-170	478.0	COG2755@1|root,COG2755@2|Bacteria,1VDI9@1239|Firmicutes,24MZY@186801|Clostridia	186801|Clostridia	E	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,SH3_3
NMLHFLOH_03046	457412.RSAG_01507	0.0	947.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3WGZI@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NMLHFLOH_03047	457412.RSAG_01506	1.62e-255	701.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NMLHFLOH_03048	1121115.AXVN01000068_gene3404	9.69e-42	136.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03049	1121115.AXVN01000068_gene3403	5.96e-152	426.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NMLHFLOH_03050	1121115.AXVN01000068_gene3402	6.98e-110	317.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NMLHFLOH_03051	1121115.AXVN01000004_gene1982	1.46e-202	560.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
NMLHFLOH_03052	457412.RSAG_00413	0.0	1201.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NMLHFLOH_03053	1121115.AXVN01000004_gene1980	0.0	1110.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_03054	1121115.AXVN01000004_gene1979	0.0	1098.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTP@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NMLHFLOH_03055	1121115.AXVN01000004_gene1978	7.65e-314	854.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NMLHFLOH_03056	1121115.AXVN01000004_gene1977	0.0	1105.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
NMLHFLOH_03058	457412.RSAG_01177	3.98e-242	669.0	2C9Y0@1|root,2ZC36@2|Bacteria,1V2CX@1239|Firmicutes,24G7R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03062	457412.RSAG_01181	2.21e-38	128.0	298NB@1|root,2ZVSX@2|Bacteria,1W4VN@1239|Firmicutes,254UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03063	457412.RSAG_01182	1.33e-105	305.0	COG1813@1|root,COG1813@2|Bacteria,1V6NP@1239|Firmicutes,25CXJ@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03065	397291.C804_05804	1.7e-17	79.3	COG1476@1|root,COG1476@2|Bacteria,1UE77@1239|Firmicutes,25J29@186801|Clostridia,27T4N@186928|unclassified Lachnospiraceae	186801|Clostridia	K	TRANSCRIPTIONal	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03067	457412.RSAG_01187	7.01e-116	333.0	COG1476@1|root,COG3093@1|root,COG1476@2|Bacteria,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	DUF4423,HTH_19,HTH_26,HTH_3,TetR_C_6,TetR_N
NMLHFLOH_03068	457412.RSAG_01189	0.0	1139.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3WHIM@541000|Ruminococcaceae	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_03069	457412.RSAG_00417	3.77e-185	541.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NMLHFLOH_03070	457412.RSAG_00418	3.92e-214	590.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3WGYB@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NMLHFLOH_03071	457412.RSAG_00419	1.28e-132	375.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_03072	457412.RSAG_00420	5.1e-123	350.0	COG4636@1|root,COG4636@2|Bacteria,1V5WZ@1239|Firmicutes,24IWJ@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_03073	1121115.AXVN01000020_gene100	3.38e-17	75.1	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
NMLHFLOH_03074	511680.BUTYVIB_01914	9.55e-06	45.8	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia,4C00Y@830|Butyrivibrio	186801|Clostridia	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
NMLHFLOH_03075	457412.RSAG_00423	1.1e-131	373.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NMLHFLOH_03076	457412.RSAG_00424	2.23e-150	423.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,3WJNC@541000|Ruminococcaceae	186801|Clostridia	P	AAA domain, putative AbiEii toxin, Type IV TA system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NMLHFLOH_03077	457412.RSAG_00426	0.0	1018.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae	186801|Clostridia	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NMLHFLOH_03078	1121115.AXVN01000004_gene1989	1.63e-43	141.0	2CIA0@1|root,341N9@2|Bacteria,1VY7T@1239|Firmicutes,251RU@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2500)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2500
NMLHFLOH_03079	457412.RSAG_00469	0.0	877.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
NMLHFLOH_03080	457412.RSAG_00470	2.06e-102	295.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
NMLHFLOH_03081	397287.C807_00107	3.34e-44	143.0	2CDC9@1|root,32RXG@2|Bacteria,1VA39@1239|Firmicutes,24MYY@186801|Clostridia,27S4M@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NMLHFLOH_03082	428125.CLOLEP_01218	2.08e-139	402.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia,3WGVV@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NMLHFLOH_03083	1214166.ALLG01000025_gene1260	1.05e-77	231.0	2C2FT@1|root,2ZCBR@2|Bacteria,1V3EW@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03084	457412.RSAG_01517	1.26e-244	671.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
NMLHFLOH_03085	457412.RSAG_01516	5.16e-185	516.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
NMLHFLOH_03086	457412.RSAG_01515	1.16e-179	502.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,3WHKV@541000|Ruminococcaceae	186801|Clostridia	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
NMLHFLOH_03087	457412.RSAG_01514	8.88e-246	676.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WSP6@541000|Ruminococcaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
NMLHFLOH_03088	1121115.AXVN01000104_gene849	0.0	1125.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NMLHFLOH_03089	1121115.AXVN01000104_gene848	1.26e-75	225.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3Y1XY@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
NMLHFLOH_03090	1121115.AXVN01000074_gene2300	3.47e-134	382.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes,24HN9@186801|Clostridia,3Y0J3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NMLHFLOH_03091	457412.RSAG_02004	1.02e-197	548.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_03092	457412.RSAG_02005	1.59e-78	234.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NMLHFLOH_03093	1121115.AXVN01000074_gene2291	3.48e-213	588.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3Y02V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
NMLHFLOH_03094	1121115.AXVN01000074_gene2290	6.61e-188	522.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NMLHFLOH_03095	457412.RSAG_02014	2.59e-143	405.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NMLHFLOH_03096	1256908.HMPREF0373_02578	4.23e-227	630.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,25VAH@186806|Eubacteriaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
NMLHFLOH_03097	1121115.AXVN01000074_gene2287	0.0	880.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYZK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NMLHFLOH_03098	457412.RSAG_00471	1.15e-204	566.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
NMLHFLOH_03099	457412.RSAG_04743	1.83e-113	326.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,HATPase_c,HisKA,PAS_7,Response_reg
NMLHFLOH_03100	457412.RSAG_00472	1.06e-72	218.0	COG0834@1|root,COG0834@2|Bacteria	457412.RSAG_00472|-	ET	amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03101	457412.RSAG_00473	8.16e-304	828.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,3WJVG@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,HisKA
NMLHFLOH_03102	1121115.AXVN01000004_gene1999	2.49e-166	465.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3Y09B@572511|Blautia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_03103	457412.RSAG_00475	3.43e-189	525.0	COG0768@1|root,COG0768@2|Bacteria,1V1CI@1239|Firmicutes,24GWI@186801|Clostridia,3WRJI@541000|Ruminococcaceae	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,Peptidase_C70
NMLHFLOH_03104	457412.RSAG_00476	3.28e-195	542.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NMLHFLOH_03105	457412.RSAG_00477	0.0	1167.0	2EXAA@1|root,33QKY@2|Bacteria,1VU9D@1239|Firmicutes,24Y4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03106	1504822.CCNO01000009_gene1694	1.17e-35	145.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
NMLHFLOH_03107	927704.SELR_23290	1.11e-92	280.0	COG1396@1|root,COG1396@2|Bacteria,1VURT@1239|Firmicutes	1239|Firmicutes	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NMLHFLOH_03108	46234.ANA_C11293	3.26e-73	233.0	COG0270@1|root,COG0270@2|Bacteria,1G4EG@1117|Cyanobacteria,1HIE4@1161|Nostocales	1117|Cyanobacteria	L	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NMLHFLOH_03109	515620.EUBELI_01790	3.39e-98	285.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,25WIB@186806|Eubacteriaceae	186801|Clostridia	L	DNA mismatch endonuclease Vsr	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
NMLHFLOH_03110	515620.EUBELI_01791	1.28e-284	778.0	28HCC@1|root,2Z7P8@2|Bacteria,1UW7H@1239|Firmicutes,24B9A@186801|Clostridia,25Y82@186806|Eubacteriaceae	186801|Clostridia	L	LlaJI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_LlaJI
NMLHFLOH_03111	515620.EUBELI_01792	0.0	1206.0	COG1401@1|root,COG1401@2|Bacteria,1TPIP@1239|Firmicutes,249RD@186801|Clostridia,25XA4@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain (dynein-related subfamily)	-	-	-	ko:K07452	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	AAA_5
NMLHFLOH_03112	411469.EUBHAL_02118	2.95e-206	570.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NMLHFLOH_03113	411463.EUBVEN_00921	3.11e-15	67.8	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03114	1121115.AXVN01000077_gene2642	8.95e-12	60.1	2C9RV@1|root,32UDR@2|Bacteria,1VD3D@1239|Firmicutes,24NEV@186801|Clostridia,3Y1XJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03115	1121115.AXVN01000095_gene459	4.46e-184	512.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,3Y1NA@572511|Blautia	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NMLHFLOH_03116	457412.RSAG_01809	8.28e-178	496.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NMLHFLOH_03117	457412.RSAG_01807	5.85e-225	619.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,3WGY7@541000|Ruminococcaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NMLHFLOH_03118	457412.RSAG_01806	4.04e-155	434.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NMLHFLOH_03119	457412.RSAG_01805	6.43e-189	523.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,3WGHV@541000|Ruminococcaceae	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
NMLHFLOH_03120	411461.DORFOR_03054	4.63e-226	622.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27VHG@189330|Dorea	186801|Clostridia	V	COG COG4823 Abortive infection bacteriophage resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NMLHFLOH_03121	1121115.AXVN01000068_gene3401	1.58e-69	211.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NMLHFLOH_03122	1121115.AXVN01000068_gene3400	0.0	1310.0	COG5434@1|root,COG5434@2|Bacteria,1V8MX@1239|Firmicutes,257MV@186801|Clostridia,3Y1ZG@572511|Blautia	186801|Clostridia	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
NMLHFLOH_03123	457412.RSAG_01500	0.0	2523.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WH6H@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
NMLHFLOH_03124	1121115.AXVN01000031_gene346	9.87e-175	486.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NMLHFLOH_03125	1121115.AXVN01000031_gene345	8.52e-208	573.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NMLHFLOH_03126	1121115.AXVN01000031_gene344	1.15e-176	491.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NMLHFLOH_03127	1121115.AXVN01000031_gene343	0.0	1731.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3XYZD@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NMLHFLOH_03128	397290.C810_04734	2.53e-250	698.0	COG3547@1|root,COG3547@2|Bacteria,1TP4A@1239|Firmicutes,24A2F@186801|Clostridia,27KFH@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NMLHFLOH_03129	1121115.AXVN01000169_gene371	4.8e-117	342.0	COG1668@1|root,COG1668@2|Bacteria,1V4GW@1239|Firmicutes,25D8Y@186801|Clostridia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2
NMLHFLOH_03130	502558.EGYY_02850	5.35e-14	79.3	2ERTC@1|root,33JCK@2|Bacteria,2HB92@201174|Actinobacteria,4CWAQ@84998|Coriobacteriia	84998|Coriobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03131	397288.C806_01682	3.19e-83	258.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,27I8U@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NMLHFLOH_03132	411459.RUMOBE_00130	3.26e-121	356.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NMLHFLOH_03133	457421.CBFG_01211	1.63e-75	248.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,268JW@186813|unclassified Clostridiales	186801|Clostridia	L	Helicase conserved C-terminal domain	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
NMLHFLOH_03134	1280680.AUJU01000013_gene2364	2.41e-47	158.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,4BY5V@830|Butyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
NMLHFLOH_03136	411462.DORLON_01361	4.17e-123	353.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia	186801|Clostridia	I	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NMLHFLOH_03137	411463.EUBVEN_00912	8.78e-40	137.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,25WZH@186806|Eubacteriaceae	186801|Clostridia	C	COG COG0716 Flavodoxins	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NMLHFLOH_03138	483218.BACPEC_02521	0.0	1026.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,26AC0@186813|unclassified Clostridiales	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_03139	483218.BACPEC_02522	0.0	1062.0	COG1961@1|root,COG1961@2|Bacteria,1TQJB@1239|Firmicutes,248GP@186801|Clostridia,26AH4@186813|unclassified Clostridiales	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NMLHFLOH_03140	457412.RSAG_03366	0.0	975.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3WHAV@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NMLHFLOH_03141	457412.RSAG_03367	0.0	1043.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3WH7D@541000|Ruminococcaceae	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,SLH
NMLHFLOH_03142	457412.RSAG_03368	3.87e-262	719.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WGRK@541000|Ruminococcaceae	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortase,YibE_F
NMLHFLOH_03143	457412.RSAG_02312	1.71e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3WIYC@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NMLHFLOH_03144	457412.RSAG_02311	2.21e-228	627.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3WSRT@541000|Ruminococcaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
NMLHFLOH_03145	1121115.AXVN01000131_gene736	0.0	1061.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3Y0FH@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.99	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
NMLHFLOH_03146	1121115.AXVN01000107_gene614	6.45e-203	563.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NMLHFLOH_03147	457412.RSAG_01696	1.59e-99	288.0	COG3543@1|root,COG3543@2|Bacteria,1VAZC@1239|Firmicutes,25DS7@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
NMLHFLOH_03148	457412.RSAG_01694	2.79e-253	694.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3WH25@541000|Ruminococcaceae	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NMLHFLOH_03149	457412.RSAG_01693	1.35e-262	721.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,3WSRQ@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NMLHFLOH_03150	457412.RSAG_01692	1.29e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,3WH9J@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NMLHFLOH_03152	1121115.AXVN01000031_gene335	3.39e-132	374.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia,3Y0F3@572511|Blautia	186801|Clostridia	K	DNA-directed RNA polymerase sigma subunit (RpoE,sigma24)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NMLHFLOH_03153	1121115.AXVN01000031_gene336	3.8e-293	800.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NMLHFLOH_03154	397291.C804_00692	5.91e-46	161.0	COG0582@1|root,COG0582@2|Bacteria,1UXHG@1239|Firmicutes,25ME8@186801|Clostridia,27SHE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NMLHFLOH_03155	1121115.AXVN01000031_gene338	1.23e-217	604.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NMLHFLOH_03156	483218.BACPEC_03095	4.52e-105	304.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,269I5@186813|unclassified Clostridiales	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NMLHFLOH_03157	585394.RHOM_01350	0.0	1096.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
NMLHFLOH_03158	515620.EUBELI_20287	0.0	883.0	COG0840@1|root,COG0840@2|Bacteria,1UIK6@1239|Firmicutes,24DFD@186801|Clostridia	186801|Clostridia	NT	(COG0840), methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,MCPsignal
NMLHFLOH_03159	1235798.C817_01827	3.68e-184	520.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27WKS@189330|Dorea	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NMLHFLOH_03160	1235798.C817_01828	1.71e-188	526.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia	186801|Clostridia	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NMLHFLOH_03161	97139.C824_03911	3.25e-186	521.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,36G1X@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NMLHFLOH_03162	457412.RSAG_02002	1.03e-246	680.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ATS@186801|Clostridia,3WI3J@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NMLHFLOH_03163	457412.RSAG_02001	2.83e-233	644.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WIHA@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NMLHFLOH_03164	457412.RSAG_02000	1.75e-174	487.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHNG@541000|Ruminococcaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NMLHFLOH_03165	457412.RSAG_01999	5.64e-75	224.0	COG5561@1|root,COG5561@2|Bacteria,1VBDY@1239|Firmicutes,259Y8@186801|Clostridia,3WQWE@541000|Ruminococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
NMLHFLOH_03166	411469.EUBHAL_02110	1.65e-205	568.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,25VAQ@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NMLHFLOH_03167	411469.EUBHAL_02111	2.8e-169	473.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,25V7E@186806|Eubacteriaceae	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NMLHFLOH_03168	411469.EUBHAL_02112	3.42e-84	248.0	28ZZK@1|root,2ZMPX@2|Bacteria,1V41I@1239|Firmicutes,24RFQ@186801|Clostridia,25WGW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03169	411469.EUBHAL_02114	4e-119	347.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,25ZTY@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
NMLHFLOH_03170	1121115.AXVN01000031_gene339	0.0	894.0	COG2942@1|root,COG2942@2|Bacteria,1UQC2@1239|Firmicutes,24D2T@186801|Clostridia,3Y1CF@572511|Blautia	186801|Clostridia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
NMLHFLOH_03171	1121115.AXVN01000031_gene340	2.89e-75	225.0	COG1115@1|root,COG1115@2|Bacteria,1VUZR@1239|Firmicutes,25092@186801|Clostridia	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NMLHFLOH_03172	1121115.AXVN01000031_gene341	8.4e-150	421.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3XZRS@572511|Blautia	186801|Clostridia	F	orotate phosphoribosyltransferase K00762	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NMLHFLOH_03173	457412.RSAG_00860	3.14e-132	374.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,3WIZ6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NMLHFLOH_03174	457412.RSAG_00862	6.51e-216	596.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
NMLHFLOH_03175	457412.RSAG_03385	1.65e-147	415.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3WIDK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
NMLHFLOH_03176	1121115.AXVN01000030_gene3611	2.42e-201	557.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3XZC4@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NMLHFLOH_03177	457412.RSAG_03383	7.32e-90	264.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3WK1B@541000|Ruminococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NMLHFLOH_03178	457412.RSAG_01898	2.11e-217	604.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,24PWJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4878,DUF5067
NMLHFLOH_03179	457412.RSAG_01899	2.67e-43	140.0	COG2155@1|root,COG2155@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF378)	yuzA	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NMLHFLOH_03182	397287.C807_01521	5.84e-144	427.0	28RNQ@1|root,2ZE1D@2|Bacteria,1V1HU@1239|Firmicutes,24GGJ@186801|Clostridia,27K2B@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NMLHFLOH_03183	397288.C806_01627	0.0	910.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes	1239|Firmicutes	L	Phage plasmid primase, P4 family	-	-	-	-	-	-	-	-	-	-	-	-	D5_N,Pox_D5
## 2993 queries scanned
## Total time (seconds): 303.74684262275696
## Rate: 9.85 q/s