LOCUS       gnlProkkaAGOJHKEG_92   14108 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGOJHKEG_92.
ACCESSION   gnlProkkaAGOJHKEG_92
VERSION     gnlProkkaAGOJHKEG_92
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:04:09
            Original ID  :: gnl|Prokka|AGOJHKEG_92
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14108
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14108
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[9474:10755]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9475..10755
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14108
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14108
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(2..409)
                     /locus_tag="ctg92_1"
                     /transl_table=11
                     /translation="MKYANALEKAGAKGWAYPTINVILRNRVYTGAMVQHKSEKISYKV
                     EKYQYIPEEQQYIVEGMHEAIISKDTFEQVQELMKKRTRTPGFNSEVRKVNPYAGIIVC
                     GDCGYNFQRVTCRDGYECGTYHKKGNTVCYSH"
     CDS             complement(406..1077)
                     /locus_tag="ctg92_2"
                     /transl_table=11
                     /translation="MMYQMGVYCRLSKDDGENKVSESIENQMKLIREYVTKSEDLEIAD
                     IYIDDGYSGLYFANRPEFQRMMEDIYKGKIQGVITKDISRLGREHIETSNYIERVFPSL
                     GVRYIAILDGVDSVHHSNEELAQFKTLFNDMYSRDISKKIRGALTAQKKRGQFMSGFAP
                     YGYVKDPADKHHFLVDEEAAKVVRRIFYMSLEGYSRDGIAKKLNQEGILTPSEYKRKCR
                     D"
     CDS             complement(1074..2663)
                     /locus_tag="ctg92_3"
                     /transl_table=11
                     /translation="MYQAGIYCRISIEEQNKEGEYSNSIHSQIQMARDYIAENKDIAEK
                     KVYVDDGASGSNFERTEFRRMLADIELGVINMVIFKDVSRLGREHIDTNYYLGKYFPEK
                     QIRIVSILDNYDSAVGTYDEMLEIKTLLNDMYLRDTSRKIKTTIQTKRSMGEYTPKQPP
                     FGYVKSKTIHNHLEIDPYAAEVVRRIYRMYQNGFGCTVICRTLNEDEIPCPAKYKKEVL
                     KTNYVWDSGKGLWTSSTVSGILKNPVYTGAVVIRKHERPSYKLKYKKAIPLEEMELVPD
                     AHEAIISKEEFDRVQQIRKGRRVSYFDKNNEPHKYVGLLFCGKCKTAMRKRYLASHKDY
                     DGYMCGFHQKQGQNYCELNHITFEKLDELVVFAINQQLKQMKMDMKNLETQIRQKQPEL
                     DGKIAKLQAKIERNLEYRKRAYEQFMDEVLSKEEYLELKQMYETENQKYQKELSELNHE
                     EQRQRAAVNETKIWLEHFNRRRITVKQLTREALVELVDKIYVYPEQKIDIYFKFASVES
                     SPDRILEKDGVI"
     CDS             complement(2740..2907)
                     /locus_tag="ctg92_4"
                     /transl_table=11
                     /translation="MNTLFDSVEVLDTKKEIQKENVSYEHAGYQIRVHFNGEKTLIQCI
                     QNLTERKIAG"
     CDS             3185..5494
                     /locus_tag="ctg92_5"
                     /transl_table=11
                     /translation="MERCDFSSISTCLKNQISESNQMNQPDFLYELFEDFMNDPINEDF
                     SMDNGLICRWITGQAKISPKITSYYAKPSNQKKLATTIQRNLLPLMADCNMVIQDIYTL
                     FIQDDTISDTKKQELVSLYKPSDSRLLFLAKVLSFGMERQFIKRDTRNQKLIAGGVLSP
                     IVLDYIMDSEVPKPCRHFLGREEELDELHTLFEENRHIFLYGIAGIGKSELAKAYAKQY
                     RKQYTNILYMEYTGNLYQDIVDMDFIDDPPEISEQERFQRHNRFLRSLKSDTLLIIDNF
                     NVTSTQDSCLSVVLKYRCRVLFTTRSQLSEYCSFQLKELKDIPTLFQLTSVFYSEAEEN
                     RAIVEKIIETVHYHTFAVELAAKLLENGILTPEQLLIKLQEEKASLHNEDKIKVMKDGQ
                     SKKATYYNHIHTLFSLYSLSRKQQDIMCNMCFMPSSGISARIFSKWLELPTLNDVNDLI
                     ETGFVQSSLRHTISLHPMIQEIAVSETAPSVTSCHTLLDSLQKICLMHGIEVSYYKKLF
                     QTVENIMLFIEKDDIPQYLLFLEDVFPYMEKYHYQKGMKKIIQELQHFIKANTYGTASD
                     RALLLDYQATLEPKTEKAIKLEKEALAQIKETTKENAHLVSNLHSNLGGLYRINGQLDL
                     AKRHMKMGISLLQQYQLLYTNDSIPQINNYAVLLIEIQEPDLALSALQKLAQIIKEYNS
                     NHCLDYAQVQESLGSICLITANISQAKTHFKKALKIYEDIWADEPELIEEKYQAIQELY
                     PQAGIALAKSILLTKH"
     CDS             complement(5733..6590)
                     /locus_tag="ctg92_6"
                     /transl_table=11
                     /translation="MRENGKTWYRICKMLCEYKKYFPGIICCLLGSSFITFIHPLLIRQ
                     ITDCGILQKNMKYILLFSVILIIISLTQQELNIIQTKLFSNVHNQFTHSLYKKTYWKIN
                     RMKIQYFAERGSAEIINTIGMDIDNVSSVVDQITQFSISSILQIIGGVVGLSLLDWKLA
                     ILIEAIIPLKFIIVSYCANKKREVFEQWIEDKRKFMSWFAECINGIHEMKLWNLFQVKK
                     SQFEGLQKDLMDSYKKNAMLDEYSTVSVVVIDTVVNALLYILSGLFIIKGEFTIGGAFA
                     FITY"
     CDS             complement(6616..7710)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 53.3; E-value: 4.5e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg92_7"
                     /transl_table=11
                     /translation="MIKLALIDNGIPYHMRNNRNQRIVHKSFLASKCDPSEYKDDKSFH
                     GAVCVGIITSICSDIELWDLNVTDSAGTTQITVLLEALEWCIQNKIKLIHMSLGTINYF
                     DIKPLWIQIKRLLDADAIIVAAYHNRNIKTYPAAYPGVFGVRQDRYGLLGNGQILFQEQ
                     KGYNIENSIIANFSWNGIVNQANSYAAPVVTGHIATYLNRKPTAGFDDVMDFLMTIATH
                     KSDYPDILENVIRDKTNIEIPVIAGIDLDYEEMIQLKVMFSQNGYYAINLQKNPLDENV
                     IPLEYYDDSNESLNDILYTVYIAYEPDIILLNQEEEIFESSKASDIDMYIVRKNNMYEL
                     YAEDRIGITYNIEDIYELVCQYFA"
     CDS             complement(7826..9346)
                     /locus_tag="ctg92_8"
                     /transl_table=11
                     /translation="MKKSVLAIMVGALCIILSSCQETPEESSVVSKVDGISEAAVCEPL
                     KKGEKRETNVPTHWKFEEKKSNDRVVIQADIKLGEQSIGNLPVIEMQNHELTQEELNGL
                     IDYFTDGEELYMPQMVTKDAYQEVLDRISSKEGSYLQSAYSTSIAGIQNATREGMELAP
                     DEASAPEKMEIKFQKKTEDHGVEAARSWMSTELENTDTEDYFTADVGEDRKAYIEAERY
                     NQEIDNDSSFLWMEGSNFIEEETIETEEMQSEYYSSFGMDTNGYTEKFHELADAYRKCM
                     DKITFTEEDGKEQAEQVLEDLGIDGMGLVDSDRTVWFPNGACSERNGLGLGSDALWQGD
                     LDRGLPGYLYCFSKSVEGITSVPDGVVAEETVDSYVPPFQVETISILITEEGIKYFKWD
                     GISEEVCTVTENTKLLPFEKIQAKLTDQIFYWYSGKGQSANDTTALEYDVVNAKLQYTY
                     TTAYQEPKHAWLVPAWIFTVRESIGGNSLQELSYVINAYDGSVIGEAY"
     CDS             complement(9475..10755)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg92_9"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.7e-14, bitscore: 43.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-16, bitscore: 51.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.4e-14, bitscore: 42.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKVLIKCIQTPMQKYFYDRSLDSVVMVNDEEYQILKTVEKTKLV
                     PDGVLRRFVKSGLLRETAIEEIEHPETENLHLLAEHYMGNLILQVTQQCNLRCKYCAYS
                     GNYYNRSHTSNRMDFETAKKAIDFYLKRSEKADQLALSFYGGEPLLEFELIKKCVSYIL
                     QRKGDKKILFTMTTNGTLMTEDVIEFLVKYEFNLMISLDGDKKSHDINRRFKTGKGSFD
                     IILENLSRLKAYNEEYYSKVLFNCVISSSSDLENIYRFYSEEELFEAGTVNFNYVNPVG
                     LKDETLSRITQKNFRVHRLAYIKMILSVLEKRKWDAQSRLLRRELQDIELLYEQLHSHV
                     AEGKKTHHGGPCIPAVRRLFVDTKGEFFPCERVSEEDSEMCIGSLDSGFDFDKMSFLLN
                     HGKMIKEKCLGCWNLRMCAYCLAQIPK"
     CDS             complement(10774..11415)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 165.4; E-value:
                     2.9e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg92_10"
                     /transl_table=11
                     /translation="MEYAIRLKGLTKSFQKEKVLKNITHDFEKGKIHGIMGFNGSGKTV
                     MFKCICGFLQPESGTVLVGGKQIGKELDFPDSVGIIIENPGFFLDLSGFANLKRLASLK
                     HRISDDDVRATMRALGLDPLSKKKVGQYSLGMRERLGIAQAIMEDPELLILDEPFNGLD
                     KQGAGEVCELLRGLKERGKTILIAAHNMLEIEWLCDTICEMDAGVLTQIK"
     CDS             complement(11428..12321)
                     /locus_tag="ctg92_11"
                     /transl_table=11
                     /translation="MRDIKQAFWIAGQNFYGWKKSPRIWMTFILAAILCLMLSDQIISH
                     AIKYETILQVFEPFIWTYGDASSVMLSSLLLILLFADMPFISQATPYWLVRTKRKIWLA
                     GQIIYVILATVIYNIFLAVMLGIMGAPFSFTGNVWSETAAMLGYGGGESITVPVSIKTM
                     ESSTPYMCAAIVFGLVLLYTLFIAVLMLFLNLAAGNMAGVIGAFAVSLYGLLLNPDVFR
                     KLFHFTESQEYRANVFCGWLSPLNQATFPMHSFGYDYLPGIGMSMFIFAILIIALIGLS
                     AVRIKGYNFSFTQTNE"
     CDS             complement(12314..13069)
                     /locus_tag="ctg92_12"
                     /transl_table=11
                     /translation="MRNVLATDIKNNIRSIRFILGIFLIVSATLMSEHEMLQKIINAGG
                     SAEGPGWFVAYTYCMNSVNMLLFVPIAVAFAGGENTEAELHSRFFLFSYIRSGRKQYLV
                     GKAAGLLVSGGLTAFLAMVFLLVICILRFGQYPSLIDGNYEMAVLVGRTAVSFLRLFLN
                     GAFWALIGGTSAVITKNRYMSYAVPFILYYVLTVFQERYYQKAFFLSPRYWAASIYYND
                     IFCIAILAVGSFLTALIFMCAIERRLRYA"
     CDS             13607..14107
                     /locus_tag="ctg92_13"
                     /transl_table=11
                     /translation="MRELRNTKIIAVDHGYGNMKTANTVTPTGIKAYETEPIFTGNILE
                     YNGIYYRIGEGHKEFIPDKAMDEEYYLLTLMAIARELNVFSIREADVHLAAGLPLTWIR
                     NQREDFRSYLLQNPEVHYRFNSKEYHLRFVGCSLYPQGYPAIVNRLGDFKGTNLLADIG
                     NGTM"
ORIGIN
        1 aatgagaata acaaactgtg tttccttttt tgtgataggt accgcactca taaccgtccc
       61 gacaagtaac cctctggaaa ttatatccgc aatctccaca aacaataatt cctgcgtatg
      121 gatttacctt tctcacttcg ctattaaatc ccggtgtccg tgttcttttc ttcataagtt
      181 cctgtacctg ctcaaaagta tctttgctaa taattgcttc gtgcattcct tccacaatat
      241 actgctgttc ctctggaata tattgatact tttccacttt ataggatatc ttttctgatt
      301 tatgctgtac catagcccct gtataaactc tgtttcgcaa aattacattg atcgtaggat
      361 atgcccagcc ctttgcaccc gctttttcta atgcattggc atatttcaat ccctgcactt
      421 tctcttatac tctgacggtg tcagaattcc ttcctgattc agtttctttg caataccatc
      481 cctggaatat ccttccaaac tcatataaaa gattctccgt accactttag ctgcttcttc
      541 atctacaaga aaatgatgct tatctgccgg atcttttaca tatccatatg gggcaaaccc
      601 agacataaac tgtccccgtt tcttctgggc ggtcaatgca cctctgattt tcttagatat
      661 atcacgacta tacatatcat taaacaacgt cttaaactgt gccaattctt cattactgtg
      721 atgaacagaa tccacgccat ccaaaattgc aatataacgc acacccaaag atggaaaaac
      781 acgctcaata tagttactgg tttcaatatg ttcacgccca agccgggaaa tatctttcgt
      841 aataacgcct tgaattttcc ctttgtagat atcctccatc atccgctgaa attccggtct
      901 attcgcaaaa taaagccccg aataaccgtc atcaatataa atatctgcga tttccagatc
      961 ctctgattta gtcacatact cacgaatcag tttcatctga ttttcaatac tctcactaac
     1021 tttattctct ccatcatcct tcgacagacg acaatataca cccatctgat acatcatatc
     1081 accccatctt tctcaagtat tctatctggt gaactctcta ctgaagcaaa cttaaaatat
     1141 atatctattt tctgctctgg atatacataa attttatcaa ctaactccac aagcgcttct
     1201 ctggtaagct gctttaccgt tattcttctg cgattaaagt gctccaacca tatctttgtt
     1261 tcattgaccg ccgcccgctg cctttgctct tcatggttca gttctgataa ttctttttga
     1321 tatttctgat tctctgtttc atacatctgt tttaattcca gatattcctc tttggaaagt
     1381 acttcatcca taaactgttc atatgctcgt ttccggtatt ccagatttct ttctattttt
     1441 gcctgcaatt ttgcaatttt accatccagt tccggctgtt tctgtctgat ctgagtttcc
     1501 agattcttca tatccatctt catctgtttc aattgctggt tgattgcaaa tacaaccagt
     1561 tcatccagct tttcaaatgt aatatgattc agctcacagt aattctgccc ctgcttctga
     1621 tgaaaaccac acatatatcc gtcatagtct ttatgagatg ccagataacg ttttcgcatg
     1681 gctgttttac atttcccaca aaagagcagt cccacatatt tatgtggttc attgttttta
     1741 tcaaaatagg aaactctgcg cccctttctt atttgctgaa ccctatcaaa ctcttcttta
     1801 gaaatgattg cctcatgtgc atccggcacc agctccattt cttccagggg aattgccttt
     1861 ttgtatttca gcttataaga cggtctttca tgtttccgaa tcacaaccgc cccagtatag
     1921 accggattct ttaaaattcc acttacagta gacgatgtcc acagaccttt tcccgaatcc
     1981 catacataat tggtttttaa aacttccttt ttatattttg cgggacaagg gatttcatct
     2041 tcattcaaag tcctgcaaat aaccgtacag ccaaatccat tttgatacat tctgtaaatt
     2101 cttcgaacaa cctcggctgc ataaggatca atttccagat gattatgaat tgttttactt
     2161 ttcacatatc caaagggggg ctgtttcgga gtatattcgc ccatacttct tttggtctga
     2221 atcgttgtct taatctttct ggatgtatct ctcaaataca tatcattcag caaagttttt
     2281 atttctaaca tttcatcata agttccaacg gctgaatcat aattatccag aatcgaaaca
     2341 atccgaatct gtttctccgg gaaatatttg cctagataat agttggtatc aatatgttct
     2401 cttccaagtc gagatacgtc cttaaaaatc accatattga taacaccaag ctcaatatct
     2461 gccagcatcc tccgaaattc agttctttca aaattacttc cagaagcccc atcgtctaca
     2521 taaacttttt tctctgcaat atctttattc tctgcaatat aatctcttgc catctgaatc
     2581 tgagagtgaa tactattgct gtattcaccc tctttatttt gctcttcaat ggaaattcgg
     2641 caataaattc ctgcctgata cattctatcc ctcttttcat cggtcttgcg tagtcattgt
     2701 ctttaattgt ctttatttta caacaagaac ttaagaaaat caacctgcaa tttttcgttc
     2761 agtaagattc tgaatgcact ggatcaatgt cttttcccca ttaaaatgca ctcgaatctg
     2821 atatcctgca tgttcatagc ttacattctc tttttggatt tctttttttg tatccagaac
     2881 ttctacagaa tcaaataacg tattcatgct atatgcctcc ttcagcatac agttctctct
     2941 acatcctatg ccggcaggat tgtacaaaag ttctgtatga attgaattcg gctttcgaaa
     3001 gcctgattac attctaaaat tattctgcac caatcacatt gaattgaaat tgaccgcaga
     3061 ttgagttttt aagattcatt ttcttcctat acagtatcaa ttcctattgt ccggaacatt
     3121 tgttcgtgtt ataataaaaa gactttaaga atataaaaca cgaaaaccaa aggagggatt
     3181 tctgttggaa cgatgtgatt tttcttctat tagcacatgc ctaaaaaatc aaatcagtga
     3241 aagcaatcag atgaaccaac ctgatttttt atacgaatta tttgaagatt ttatgaatga
     3301 tccgataaat gaagattttt ctatggataa tggtctaatt tgccgctgga taaccggaca
     3361 agcaaaaatc agtcccaaaa taacctcata ttatgcaaaa cccagcaatc agaaaaaact
     3421 ggcaacaacc attcagcgga acttacttcc cttaatggca gactgcaaca tggttataca
     3481 ggacatttac acgttattca tacaggacga tacgatttcg gatacaaaaa agcaggaact
     3541 tgtatctcta tataaacctt ctgattcaag gctgttgttt ttagcaaaag tactttcttt
     3601 tggtatggaa cggcaattta ttaaacgtga tacaagaaat caaaaactga ttgcaggagg
     3661 tgttctatct ccgattgttc tggattacat tatggacagc gaagtcccaa aaccatgccg
     3721 tcattttcta ggaagagaag aagaactgga tgaactccat actttgtttg aagagaaccg
     3781 acatatattt ctttatggaa ttgccggaat tggaaaaagc gagcttgcta aagcctatgc
     3841 aaagcaatac agaaaacagt acaccaatat tctctatatg gaatacaccg gtaatctata
     3901 tcaagatatt gtagacatgg attttattga tgatccacca gaaatcagtg agcaggaacg
     3961 ttttcaaaga cataaccgtt tcttacgctc tttgaaatct gatacactgc tgatcataga
     4021 caattttaat gtcacatcca cacaggacag ttgcctgtca gtcgtattaa aataccgttg
     4081 ccgggtttta tttacaacca gaagccaact gtctgaatac tgtagttttc aattaaaaga
     4141 actgaaagat atacccactc tttttcaact gacatctgta ttttattcag aagcagagga
     4201 aaaccgggca atcgtagaaa aaatcataga aactgtacac taccatactt ttgctgtcga
     4261 actggcagcc aaacttctgg aaaatggaat tttaactcca gagcaattat tgataaaact
     4321 tcaagaggaa aaggcttctc ttcataatga agataagatt aaagtaatga aagatggtca
     4381 gagcaaaaaa gccacctatt acaaccatat ccataccctg ttttcgttat actccttatc
     4441 acggaaacag caggatatta tgtgcaatat gtgttttatg ccttcatctg gtatttctgc
     4501 ccgtatattt tccaaatggc tggagctgcc tactttaaat gacgtgaatg atctgatcga
     4561 gacaggtttt gtacagtcaa gtctccggca tactatttct ctgcatccaa tgattcagga
     4621 aattgcagtt tccgagaccg caccttctgt tacaagctgc cacacgttat tggattctct
     4681 gcaaaaaata tgtttgatgc atggcattga agttagctat tataaaaaat tatttcaaac
     4741 agtagaaaac atcatgcttt tcattgaaaa ggacgatatt ccccaatacc tgttattttt
     4801 agaagatgtt tttccatata tggagaagta ccactatcaa aagggtatga aaaaaatcat
     4861 ccaggaacta cagcatttta taaaagcaaa tacttacggg actgcatctg accgtgcctt
     4921 actattggat tatcaggcaa ctctggaacc caaaacagaa aaagcgataa aattagaaaa
     4981 agaagcactt gctcaaataa aagaaaccac aaaagaaaat gcccacctgg tttccaacct
     5041 ccattccaat cttggagggc tttaccgaat caacggacaa cttgatctcg ctaaaaggca
     5101 catgaaaatg ggtatctctc ttttacaaca ataccagctt ctttatacta atgacagtat
     5161 tcctcagatt aataattatg ctgtcctctt aattgaaata caagaacctg accttgccct
     5221 gtctgctctt cagaaattag cacagattat caaagaatat aattcaaacc actgtttgga
     5281 ttatgcccag gtacaggaat cccttggaag tatctgcctg atcactgcaa atatttcgca
     5341 agcgaaaacc cattttaaaa aagccttgaa aatttatgag gatatatggg cagacgaacc
     5401 cgaattgatt gaagaaaaat atcaagcaat tcaagaattg tatccacaag ctggaattgc
     5461 tctggcaaaa agtattcttc tcaccaagca ctaacggttc ctacaaacac ttgtaaaata
     5521 tattgcctca ataatgtaaa cgcctagttt tgagatacac tccaagacta ggcgcttgtc
     5581 catttccatt ttttcttaga catggagcgt ttacataagg atcacttttc tttttttgac
     5641 acttttcgct cctcctatct caaatttttt atagtctagg tatattgcct tcatcaatgc
     5701 ctgagaactt gtaaatatgc tcctctgctt gttcaatatg taataaaagc aaatgctccg
     5761 cctatagtga attctccttt tattataaaa agcccactta atatatataa taacgcattt
     5821 acaaccgtgt ctattactac aacactgaca gtactatatt catctagcat tgcgttcttt
     5881 ttatatgaat ccatcaaatc tttttgcaga ccttcaaatt gagatttttt tacctgaaac
     5941 agattccaga gcttcatttc atgaattcca tttatacact cggcaaacca actcataaac
     6001 tttcgtttat cctcaatcca ctgttcaaac acttcccgtt tcttgtttgc acaataggac
     6061 actattataa atttcagtgg aataattgct tctatcaata ttgctaattt ccagtctaat
     6121 aaggacagcc caactactcc tcctattatt tggagaattg atgatataga aaactgagta
     6181 atctgatcca caacagatga cacattatca atatccatac caattgtatt tataatctct
     6241 gcacttcctc tttcagcaaa atactgtatt ttcatcctat tgattttcca gtaagtcttt
     6301 ttatagagag aatgtgtaaa ctgattatgt acatttgaaa ataattttgt ttggattata
     6361 tttaactctt gctgggttaa agaaattatt attaatataa cagaaaataa aagaatgtat
     6421 ttcatgtttt tctgcaatat accacaatct gttatttgtc ttataagcag tgggtgtata
     6481 aacgttatga atgatgaacc caaaaggcaa cagataatcc ctggaaaata ctttttatat
     6541 tcacacaaca ttttacaaat tcgataccat gttttcccat tttctctcat atccaattgc
     6601 catcctcact attcgttaag caaaatattg acaaacaagc tcatatatat cctctatatt
     6661 gtaagttatt cctattcgat cttctgcata caattcatac atattatttt tacgcacaat
     6721 atacatatct atatctgatg ccttactact ttcaaatatt tcttcctctt gattcaaaag
     6781 aataatatca ggttcataag ctatatatac tgtataaagg atatcgttca atgactcatt
     6841 ggaatcgtca taatattcta aaggaattac attttcatct aaaggatttt tctgcagatt
     6901 tattgcgtaa taaccgttct gactaaacat cacttttagc tgtatcattt cctcgtaatc
     6961 taaatcaata ccggcaatta ccggtatctc tatattggtt ttatccctta ttacattttc
     7021 tagtatatcc ggataatcag atttatgcgt tgctatagtc atcaaaaagt ccataacatc
     7081 atcaaatcct gctgtgggct ttctgtttaa atatgtagca atatgtccag tgacaacagg
     7141 agccgcataa ctattggctt gatttacgat cccattccac gaaaaatttg ctataataga
     7201 attctcaata ttataacctt tttgttcttg aaacagaatt tgaccatttc ccaaaagacc
     7261 ataacgatcc tgcctgacac caaaaacacc tggatatgca gctggataag tctttatatt
     7321 tctgttatga tatgctgcta ctataatcgc atcagcatca agtaatcttt ttatttgaat
     7381 ccataagggt ttaatatcaa aataattgat tgttccaaga ctcatgtgaa ttaactttat
     7441 tttattttga atacaccatt ccaaagcttc cagcaaaact gtgatctgtg ttgttcctgc
     7501 agagtcagtc acattcaagt cccataattc tatatcacta catatgcttg tgataattcc
     7561 gacgcataca gcgccatgga atgatttatc gtctttatac tcacttggat cgcatttaga
     7621 agccaaaaaa gatttatgaa caatcctttg attcctgtta tttctcatat gataaggtat
     7681 accgttatca atcaatgcga gcttaatcat ttgcactatt cctattctta cctgttatat
     7741 atccaagcca aatatcgcat atttattatt ctcatgataa accttgtaat tctatggtca
     7801 ataaaaattc aagtgtcgct gaaccctaat atgcttctcc aatcacactg ccatcataag
     7861 cattgatcac ataagaaagc tcctgtagag aatttccacc aatactttcc ctgacagtaa
     7921 aaatccatgc tggaaccaac catgcgtgtt tcggctcctg ataggctgtg gtataagtat
     7981 actgcaattt tgcgtttacc acatcatact ccagtgcggt agtgtcgttg gcagactggc
     8041 cttttccgga ataccaataa aaaatctgat ctgtcagctt tgcctgtatt ttttcaaaag
     8101 gcagaagctt tgtattttcc gtcaccgtac agacttcttc cgatatccca tcccatttaa
     8161 aatatttaat tccttcctct gttatcagaa tagagattgt ttctacctgg aacggaggca
     8221 cataactatc cactgtttct tccgcaacca cgccatcagg aactgaagta ataccctcta
     8281 cacttttcga aaaacaatac agatatcccg gtaatcctct atccagatct ccctgccaca
     8341 aagcatcact accaagtccc agaccattgc gctctgaaca tgcgccattc gggaaccaca
     8401 cggtacgatc agaatctaca aggcccattc catcgatacc taaatcctct aaaacttgtt
     8461 ctgcctgttc ctttccatct tcctctgtaa aggtgatctt gtccatgcac tttcgatacg
     8521 catctgccag ttcatgaaat ttctctgtat agccgttggt atccatgcca aagctactgt
     8581 aatactcact ctgcatttcc tcagtttcta ttgtttcttc ttctataaaa ttagaaccct
     8641 ccatccagag aaaactactg tcattgtcaa tttcctgatt ataccgctct gcttctatat
     8701 atgccttcct gtcctcgccc acatctgcag taaaataatc ctctgtatct gtgttttcca
     8761 attcagtact catccaactc cgtgccgctt ccacaccgtg atcctctgtt tttttttgaa
     8821 attttatctc catcttttcc ggtgcagacg cttcatccgg tgcaagctcc atcccctctc
     8881 gggttgcgtt ttgaatccct gcaatcgatg tagaatatgc tgattgcaag taacttcctt
     8941 ccttgctgga aatcctgtct aacacttcct gatacgcatc ctttgtcacc atctgtggca
     9001 tatatagttc ctcaccgtcc gtaaaataat caatcaatcc attcagttct tcctgcgtta
     9061 actcgtgatt ttgcatctct atgactggaa gattgccaat gctttgttcg cccaacttaa
     9121 tatctgcctg gataaccaca cggtcgttgc ttttcttttc ttcaaatttc caatgcgttg
     9181 gaacatttgt ctctctcttt tctccttttt taagaggttc acagacagcc gcctcgctaa
     9241 tcccatccac tttgctgact accgaactct cctctggtgt ttcctgacag ctggaaagaa
     9301 taatacacaa cgcacctacc ataattgcta gaacactttt tttcattttt cctccatata
     9361 tcttatagaa ttgtcgcttt ttcacgaaac ttcaattata aactctttaa cttataaata
     9421 ccttcctgac actattaacg ttttcgtata ttttttagaa acagactacc ttatttattt
     9481 tggaatttgc gccaaacaat atgcacacat tctcaaattc caacatccta aacatttttc
     9541 tttaatcatc ttaccatggt taagtaggaa actcatttta tcaaaatcaa atcccgaatc
     9601 caaacttccg atgcacattt ctgaatcttc ttccgaaact ctttcacatg gaaaaaattc
     9661 accttttgta tccacaaata gtcttctaac tgcaggaatg catggaccac catgatgtgt
     9721 ttttttgcct tcagcaacat gactatgtag ctgttcatat aataactcaa tatcttgcag
     9781 ttctcttcgc aacaatcgac tttgtgcatc ccattttcgc ttctctaata cagataaaat
     9841 catctttata tatgctagtc gatgtactct gaaatttttt tgtgttatgc gcgacaatgt
     9901 ctcatctttt aaaccaactg gatttacata attgaaattc actgtccctg cttcaaacag
     9961 ctcttcttcc gaataaaatc gatatatatt ttcaagatct gatgaagaac taataacaca
    10021 attaaacaaa acttttgaat agtactcttc attgtaagct ttcagtctac tcaaattttc
    10081 taaaataatg tcaaatgaac cttttcctgt tttaaatctt cgatttatat cgtgactttt
    10141 cttatcacca tcaaggctaa tcataagatt aaactcatat tttaccaaaa attctatgac
    10201 atcttctgtc attaaagtcc cattagtcgt catagtaaaa agaatttttt tatccccttt
    10261 acgttgtaaa atataggaaa cacatttctt aatcaattca aattccagaa gaggctcacc
    10321 cccataaaat gataatgcaa gttgatccgc tttttcgctt cttttcaaat aaaagtctat
    10381 tgcttttttg gctgtctcga aatccatcct atttgacgta tgggaacgat tatagtagtt
    10441 tccagaatat gcacaatatt tgcatctcaa attacactgc tgagttacct gcaaaatcag
    10501 attgcccata taatgttctg ccaacaaatg taagttttct gtctcaggat gctcaatttc
    10561 ttctatcgca gtctcacgca ataatccgct tttcacaaac cgtcttaaca ctccatcagg
    10621 aaccaatttt gtcttttcca cagtttttaa tatctgatat tcttcatcat tcaccataac
    10681 tacagaatcc aaagaacgat cataaaaata tttctgcatt ggtgtttgaa tgcatttaat
    10741 taataccttt cccatattct ttcccccgta tttttatttt atctgcgtca ggacacctgc
    10801 atccatctca cagatcgtat cgcagagcca ttcgatctcc agcatgttat gtgctgcgat
    10861 aagaatagtc ttccctcgtt cctttaatcc ccgcaaaagc tcgcagacct ctcctgcccc
    10921 ctgcttgtcc agaccattaa aaggctcgtc caatatcaaa agctccggat cttccatgat
    10981 tgcctgtgcg ataccaagac gttcacgcat tccaagagaa tactgtccta ccttcttttt
    11041 agacagagga tcaagcccta gggcacgcat cgtcgccctc acatcgtcat cggaaatacg
    11101 gtgtttcaga gacgccagtc tctttaaatt cgcaaaaccg ctgagatcca gaaagaagcc
    11161 agggttttca atgataatgc ctacggaatc tggaaagtcc agctccttcc cgatctgttt
    11221 tccccctacg agcactgtgc cgctctcagg ttgtaaaaat ccacagatgc atttaaacat
    11281 tacggttttc cctgaaccgt taaaccccat aatcccatga atcttccctt tttcaaaatc
    11341 atgggtaatg ttctttaata ctttttcttt ttgaaaggat tttgtcagtc ccttcaacct
    11401 gattgcatat tccattttgc cctccattta ttcgtttgtc tgcgtaaaag agaaattata
    11461 gcccttaatt cggacggctg acaagccgat cagcgctatg attaatattg caaatatgaa
    11521 catgctcatc ccgatccctg gcaggtaatc ataaccaaag ctgtgcatgg gaaaggtagc
    11581 ttggttcaac ggagacagcc agccgcagaa cacgttcgcc ctatattcct gactttctgt
    11641 aaaatgaaac agtttccgga aaacatctgg gttcagcagg agcccataca gactgactgc
    11701 aaaagcaccg atcacccctg ccatatttcc cgcagccaga tttaaaaaca acatgagaac
    11761 tgcgataaaa agagtatata aaagtacaag tccaaacact attgctgcgc acatataagg
    11821 agttgagctt tccattgttt ttatggaaac aggaacggtt atgctctccc caccgccata
    11881 gcccaacatt gccgctgttt cgctccacac atttcccgta aaggaaaagg gagctcccat
    11941 aattccaagc atcacagcca aaaaaatatt atagatcaca gtcgccagga tcacatagat
    12001 aatctgaccc gcaagccata tcttccgttt tgtgcgtaca agccaatacg gagttgcctg
    12061 actgataaat ggcatgtccg caaagagcag gattaaaagc agggaggaca gcataacaga
    12121 ggatgcatcc ccatatgtcc aaataaacgg ctcgaatacc tgaaggattg tctcatattt
    12181 tatcgcatgg gaaataatct gatccgacag catcagacat aatatagctg ccaaaataaa
    12241 ggtcatccag atcctcggac tttttttcca tccatagaaa ttctggcctg caatccaaaa
    12301 agcctgttta atatcacgca taccgcaacc ttctttctat tgcgcacata aagatcagtg
    12361 ccgttaaaaa acttccaacc gctaatatag caatgcagaa gatatcattg tagtaaatag
    12421 acgccgccca atagcgggga ctcagaaaga atgctttttg atagtaacgc tcctgaaata
    12481 cggtcaggac ataataaaga ataaaaggaa cggcatagga catatagcga ttttttgtta
    12541 tgacagccga cgtaccgcca attagcgccc aaaaagcgcc atttaaaaac aatctcagaa
    12601 agcttaccgc cgttctgccc acaagcactg ccatctcata atttccgtca atcagagaag
    12661 gatactgacc gaacctcagt atacagatta caagaaggaa caccatggct aaaaaagctg
    12721 tcaaacctcc ggagaccaac aatcctgctg cttttcctac gagatactgt tttctccctg
    12781 aacggatata actgaacaga aaaaaacgac tgtgcagctc agcctccgta ttctctccac
    12841 ccgcaaaagc aacggcaatg ggaacaaaca gaagcatatt aacgctgttc atacaatagg
    12901 tgtatgctac gaaccagcct ggtccttctg cagatccgcc tgcatttatg atcttctgca
    12961 acatctcatg ctcagacatc agggtagccg aaacgattag aaaaatcccc aaaataaagc
    13021 gaatgcttcg aatattgttt tttatgtccg ttgccaacac atttctcata cgcttttctc
    13081 ctcacttcaa acagctatag acttgatttt tttattttta taaaatccta gttttttgca
    13141 ataatatcac tatttgtata aaactacact ccttatcaaa caacagttaa ggacttgcaa
    13201 aaactgttgt tcctactgaa agcattgcaa cagctgtaaa aattgataat attttaaatt
    13261 ttctattatt ctaagttcta caaatacata agccgccagt taagtacgat tagttttatt
    13321 ataattcaat aaattccatc caactttcca cattttattg tgcaatttta ccatttatat
    13381 aataacatgt caacatttaa tgaacgttta taacaaaaaa atgcagggct ataaaaaact
    13441 aaagaaattg ctctatttta caaaattata tcctattttt caattccaac tcaattttcc
    13501 ctcaatgtct ttttcctcca actttcgtat gcttatctca cagcaaagca gtaccacacc
    13561 ggtacagcct gctgaattaa tcaatacgaa aatggaggtg ttttttatgc gagaactcag
    13621 aaacacaaaa atcattgctg tagatcacgg ctacggcaac atgaaaacag caaataccgt
    13681 cacaccaacc ggaatcaaag cctatgaaac agaacccatc ttcaccggga atattctgga
    13741 atataacggc atttactacc ggattggcga aggacacaaa gaatttatcc cagataaagc
    13801 tatggacgaa gaatattatc ttctaactct catggcgatt gcaagggaac tgaatgtctt
    13861 ttccatccgt gaagcagacg ttcatctggc tgccgggctt cctctgacat ggatcagaaa
    13921 ccagagagaa gatttccgtt cctatctgct ccagaatcca gaagtccatt accgatttaa
    13981 cagcaaagag tatcatctcc gttttgtggg atgcagcctt tacccgcagg gatatccggc
    14041 tatcgtaaac cgacttggag atttcaaggg gacaaatctt cttgcagata tcggcaacgg
    14101 aaccatga
//
