LOCUS       c00035_gnlPro..        15307 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EAIJFICP_35.
ACCESSION   c00035_gnlPro..
VERSION     c00035_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:34:48
            Original ID  :: gnl|Prokka|EAIJFICP_35
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15307
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15307
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1061:5307]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1062..5307
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..15307
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15307
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(3..401)
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MTLDYFYGQTGELFSFYRIPKALFQEQRFQSLSTDAKTLYGILLD
                     RMSLSVKNGWLDKQNRVFIIFTIEDVKRALCCADNKATKLLRELEKFGLIERKRRGQGK
                     PSLVYVKNFSAESSKESVKNRDNDDSCGF"
     CDS             complement(391..798)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="VEITGIEPVTSCMPCKRSPERYRNTPPTRKCGDRLNIALIRSIHQ
                     KGSQLHPASRNHAPPTRQFYHPIFKCVNGFCSERRSFTRKVFSDSLLSAILILHIKVAL
                     FIFPKSIDKEVFSTMPMYYRCFLSMNQPHDP"
     CDS             complement(1062..2273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_3"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.1e-14,
                     bitscore: 42.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEEQLHRLPTPCYLLDEAQLRRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RADEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWNAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEEKFAGLLPRM
                     KWLNFGGGHHITRPGYALDTLESCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     CNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDAPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAQ"
     CDS             complement(2273..3532)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_4"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 5.8e-45, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 2.1e-33,
                     bitscore: 105.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTTTKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             complement(3572..4450)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="Arginase (E-value: 6.8e-77, bitscore:
                     249.1, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAV
                     RHESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALSDIEARAEEILKDGKFPLL
                     LGGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGH
                     IHQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCF
                     PGTGTPEAGGVSFLQLLDAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLI
                     ALDKGWPGFQV"
     CDS             complement(4450..5307)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_6"
                     /sec_met_domain="Spermine_synth (E-value: 4.8e-54,
                     bitscore: 173.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 5e-23, bitscore:
                     71.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFSEFHTPDVKHSIRVNKQLYSKQSDYQRIDIFETPEFGRVL
                     TLDGNVMLTERDEFIYDEMIVHVPMAVHKEAKDILVIGAGDGGVVRELTRYDRVERIDL
                     VEMDPQVVEACRAYLPGNACRMDDRRVHIYFENALKYIRRCEEEYDLIIVDSSDPFGPS
                     EGLFTREFYGSCFNALKEDGIMVNQQGSPFYAEDASAMQRSHKRIASTFPISRVYQAHI
                     PTFAAGYWLFGFASKKYHPIDDLDAEAWKALNMRTRYYTTKLHIGAFYLPAFLEEMLRE
                     VEEH"
     CDS             complement(5320..6786)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg35_7"
                     /sec_met_domain="OKR_DC_1_C (E-value: 7e-12, bitscore:
                     36.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.8e-123,
                     bitscore: 401.9, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENRTRFRLDQRRAPIYEALEQFRQMRVVPFDVPGHKRGRGNPE
                     LTAFLGQQCVGVDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSSVQS
                     MVLTACKRGDEIILPRNVHRSVLNALVLCGAVPVYVNPEVDKRLGISLGMKREQVAKAI
                     KEHPNAVAVLVNNPTYYGICSDLRAIVKMAHDAGMLCLADEAHGTHFYFGGGLPVSAMA
                     AGADMASVSMHKSGGSLTQSSLLLIGPNVHPGYVRQIINLTQTTSGSYLLMSSLDISRR
                     NLALRGRQVFHQVADIAEYAREEINAVGGYYAFGKELCNGDSVFDFDTTKLSVHTLDIG
                     LAGIEVYDILRDEYDIQIEFGDIGNILAYLSIGDRPQEVERLVSALAEIKRRYRTDGSG
                     LLSQEYIDPVVAASPQEAFYAPKKSLPLRETEGMVCSEFVMCYPPGIPILAPGERITKE
                     ILNYIEYAKAKGCSMTGPEDPEILHLNVLA"
     CDS             7351..8094
                     /locus_tag="ctg35_8"
                     /transl_table=11
                     /translation="MEKEGVWMALPIAIVEDQAADARRLEELLQQQLPEAECTWFTCGD
                     DFLRAAAEPGLYAVVFLDICMAGTNGIETARRLRQADPEVLIVFVTSSPEYVWDAFPVH
                     PFDYLLKPYQKEKFVHLAAELRRALRCKEPELEIRIARQSIQLPLRKVLYAIARNHYVL
                     ITTEDGEYRAMCSFAQIEEKLTALENFMSCNRGVIINMDKVLRFGEDCIEILDGTRLPV
                     RQKDKCTLLAHFTQYQFRHMRQELH"
     CDS             8112..9428
                     /locus_tag="ctg35_9"
                     /transl_table=11
                     /translation="MDLALFGRYFLDFALLYPSAFLCLASLWEKLRTPRRTACIAAGCI
                     TLLCIGCAALCAVFGLNSNSLLPAIVLVSFWLLRWRVTPEVTVSQTAFLFSISAVMMAV
                     CSLLSTLLNAQTEISNPQTVCLASTALLRLGLAAMLTVLFWFTAVQWSRWLLREYSGEA
                     FWQSAWPLPALYAVFLVYCMPLNPAVVLVGRLKIISVLAVSISLFGIFLLLYEMYRVAR
                     EFTRNARLDRENQLLAMESRRYMELQTYLDNTRRLRHDFRQHLHVIAGLTETGQLEELK
                     SYLHQYESELSEHRPSLCANAAVDALAGYYDHAAGQQSVPVEWKLALPRQLPMPEADLC
                     TILGNLLENALHASQKLPPEQRRVQVMAQMLSPAMLGLVVENRYDGMLKKQQGILHSTK
                     HEGTGIGLVSAETVVHKYNGNLHLETEEQIFRVNVLLNL"
     CDS             complement(9514..9753)
                     /locus_tag="ctg35_10"
                     /transl_table=11
                     /translation="MGFFAVLAASLFAVFIFTVFGGYSLLLWCQQSLWMVVPPALVLAV
                     LVWTFLKMDDKITALQKRVDELEAAQKSTEKLEK"
     CDS             complement(9773..10249)
                     /locus_tag="ctg35_11"
                     /transl_table=11
                     /translation="MIYDTLNNLPNYLGVSDNLDTVIEYIMARDITTLPAGRTRIDGDK
                     AVVTVSTVTPQTSDKALFQRHDNHITLETDLDGSELFEVSLAELTPTKPTDEAADTTVG
                     TAGTSIAGMLCEGRFALYLAGEPYKSGLKAQGCGKLKKAVFSIELDPDEEETEE"
     CDS             complement(10718..12241)
                     /locus_tag="ctg35_12"
                     /transl_table=11
                     /translation="MTAVIYARYSSDNQREESIEGQIRECTAYAEKNGITVIKHYIDRA
                     LSAKTDNRPDFQQMIKDSEKRLFDIVLVWKLDRFARNRYDSAHYEYQLERNHVKLVSAT
                     EPISEGPAGIMVKSMLTGMAEYYSAELSEKVVRGMTENVLKGKYNGGTIPIGYTVDEEK
                     FFQIDPLKAPFVVEAFQRYNDGATMKELMNWLNDSDVTTNRNQKFTYNSIQTLLTNRRY
                     IGENRFKDIVMPDSIPVIIEKELFDSVQDKIAKNRRAPAPHKAEDDYLLTTKLFCGMCG
                     AMMFGECGTSRNKNVHHYYKCANAKRTKTCKKKTVRKEWLEDLVVNETMKMIRDDDSIQ
                     SIVDAVMILQEQENTVLPLLEKQMKDIENGIENLLNAIQAGVLTSSTKGRLEKLEAQQK
                     ELEIRIAEEKLAKPKVSAEFVKFWLTNFRKLDPNVKSHRETLINTFVNAVYLYDEKVLI
                     AFNYKDGTKTITFDEIAAKDAPEGNGSDLGCFAPPKSLSVCKCAEVFVL"
     CDS             complement(12440..12613)
                     /locus_tag="ctg35_13"
                     /transl_table=11
                     /translation="MNWNELWMTVFGTTHWLGLDLGFWVSMGVVALIVVAMNAVFWGMK
                     PQKKPTDQPKAV"
ORIGIN
        1 ttgaagccac aagaatcgtc attatcacga ttcttgacac tctcttttga agattctgcc
       61 gaaaagtttt tcacatatac caaacttggc tttccttgcc ctcggcgttt tcgttcaatc
      121 agaccaaact tttcaagttc ccggagcagc ttggttgctt tgttgtctgc gcaacacaat
      181 gccctcttga catcctcgat tgtgaagatg atgaacaccc ggttttgctt gtccagccag
      241 ccgtttttca ccgacaggct catgcggtcc agcaggatac catacagggt tttggcatcc
      301 gtggacaggc tctggaaccg ctgctcctga aaaagagcct ttggaatgcg gtagaaggag
      361 aaaagctctc cagtctgtcc gtagaagtag tcaagggtca tgcggttggt tcatggataa
      421 aaaacagcga taatacatcg gcatcgttga gaaaacctcc ttgtcaatac ttttggggaa
      481 aataaaaagc gcaactttga tgtgtaaaat caaaattgcg ctaagtaagc tgtcagaaaa
      541 aacttttctc gtaaatgacc ttctctctga gcaaaaccca ttgacacact tgaaaattgg
      601 gtggtaaaat tgccttgtag gcggagcatg attcctggaa gcaggatgca actgtgaacc
      661 tttttggtgg atagaacgta tcaacgcgat attaagcctg tccccgcact ttcgtgtggg
      721 gggtgtgttt cgataccgtt cgggagagcg cttgcatggc atgcaagagg tcaccggttc
      781 gatcccggta atctccacca gaacgaaagc actacacaaa aacgtgtggt gcttttttgt
      841 tgctgccaaa cgagtgaggg tttagctcac ccaggagagt gccgtgcatg gactgcaaga
      901 gggtcaccgt gatcagaatc ggcccggtaa tctccaccag aatgaaagca ctacacggaa
      961 acgtgtggtg cttttttgtt ttatctgccg ttcaccttac gtcctctttc atgaaaaaag
     1021 cgtttgtcgc agcccgcagg ccgtgacaaa cgctttttat tttactgtgc acccagacgc
     1081 attttgaagt cctgatagcc aaagtgcacc agctcccggc aattgccgtc tgcgcccagc
     1141 agccagatgg gcggcagggg catcccattg aaggtgttgt tcttgcaggt ggtgtagatg
     1201 gccatatcgc cgaaaatgag cttatcgccc tcggcaaggg gggcgtcaaa gctgtaatcc
     1261 ccgatgatat cccccgcaag gcaagtgggg ccgcccagtc ggacggtgtg cgccttctcc
     1321 cctgcctcgc cggcgtccag cagcggcggg cggtagggca tctcgatgac atccggggtg
     1381 tggcaggctg cggacatatc cagaatggca aggctggtat ccccgttgca cagggtgtcc
     1441 agcacggtag tgaccagata gcctgcgttc agcgcccaag cctcgccggg ctccagatac
     1501 acctgtacgc cgtacttctg ccgcaccgaa aggatgcagc tttccagcgt gtcaagagca
     1561 taacccgggc gggtgatgtg gtgtcccccg ccgaagttga gccatttcat tctgggcagc
     1621 aggccggcaa acttttcctc caccgctgcc agcgttaccg ccagcgcgtc cgcgtcctgc
     1681 tcgcagagtg tatgaaagtg cagaccgtcc agcagggcgg gcagctccgg gtgcgctgcc
     1741 acagcggcgt tccactgagc acgggtggtg cccagacggc tgccgggggc gcaggggtcg
     1801 taaatttcat gaccctcctg cgtggagcac tccgggttga tgcgcagacc gatgcttttg
     1861 cccgctgcct ttgccgccgg gccgaacttt gccagctggc tgggcgagtt gaacacgatg
     1921 tggtcggcgt actgcagcaa ttcctcaaac tcatctgccc ggtaggcggc acagaacaca
     1981 tggttctcct tctccggcag ctcttccctg cccaagcgac tctcgtacag gccgctggcc
     2041 tcggtacctg ccagataggg tgccagcacc gggtagacat tgaagttgga aaaagccttc
     2101 tgcgccagca gaatgcggca gccggtgcgc tgctgcaccc ccagcaggat ctcgccgttg
     2161 cggcgcagct gggcttcgtc cagcagatag cagggggtgg gcaggcggtg cagctgctcc
     2221 tcggacaggt ttgccagccc cgcaaagggc gggcggctgt cgcgcacccg catcagtcca
     2281 ccagagccgg gttatggctc tcggagcggg gcaggccgta cttatccagt gcatccagat
     2341 acggatcggg atcaaactcc tcgacagtgt gcacgccctt ggtggtccac ttgccggtga
     2401 gcagcatcag tgcaccacac atggcgggca cgccggtggt gtagctgatg gcctgactgc
     2461 ccacttcctt gtagcactcc tgatggtcgc agacgttata gatgtagtag gtcttatcct
     2521 taccgtcctt tttgccggta aagatgcaac caatattggt cttgcccttg gtacgggggc
     2581 caaggctggc ggggtccggc agcagagcct tgaggaactg gatgggcacg atctcctgtc
     2641 cgttgaagtt gacaggggtg gtggacagca tgcccacgtc ctccagacag cgcatgtggt
     2701 ccagatagct ctggccaaag gtcatgaaga agcggatgcg ctttgcctcc gggatgttct
     2761 ttgccagaga ctcgatctcc tcatggtgca gcaggtacat atccttgtcg cccacctgat
     2821 cgaagttgta ctcccgcttg atgctcatgg ccgggatctc cacccagtgg ccgttctccc
     2881 agtagctgcc gggggcagac acctcgcgca gattgatttc agggttaaag ttggtggcaa
     2941 aggcatagcc gtggtcgccg ccgttgcagt ccagaatatc aatggtgtcg atggtatcaa
     3001 actcgtgctt ttttgcgtag gcgcagtaag cctgggtcac acccgggtcg aagccgctgc
     3061 ccagcagagc ggtcagaccg gcttcctcga actttttggc ataggcccac tgccagctgt
     3121 aatcaaagta ggcagagaag ccggcctcct tgcagcgctt ctcatagatg gcacgccact
     3181 ccgggtcgtc ggtgttctca ggctcatagt tggcagtgtc catgtagttg acgccgcagg
     3241 caaggcaggc gtccatgatg gtcagatcct gataaggcag ggcgatgttc atcacgaggt
     3301 cgggctggta ggccttgatg agggcgatga cctcctccac cttgtctgcg tccacctgtg
     3361 cggtggtgat cttggtagta gtggtgggag ccagctcagc agccagctta tcgcactttg
     3421 ccttggtacg gctggcgatg cagatctcgg tgaacacctc gggcacctgg cagcacttat
     3481 ggatggcaac agaggccacg ccgccgcagc cgatgatcag aactttgctc atgtcggtta
     3541 ctcctttatc tgtaaaatgg taggttcgta tttatacctg aaagcccggc cagcccttgt
     3601 ccagcgcgat cagggtctcg cgcagcacct tgcaggcggt ggcggtggaa acgccggtgg
     3661 tgtccagtgt gggggccagc tcgttcaggt ctgcaccgat gatgttggcc ttggtcacag
     3721 tgcggatggc atccagcagc tgcaaaaagc ttacgccgcc agcttccggg gtaccggtac
     3781 ccgggaagca ggaggggtca aggcaatcaa ggtcgatagt cagatacacc ggcaccttgc
     3841 tctcgcacag ctgtgcggtc agttcggcaa ggccggtaaa atcgaacttg tgcatctcgg
     3901 tgtgctgagc agcaaactca aactctgccc ggtcgccgct gcggatgcag aactgatgga
     3961 tgtggccatc ccctaccagc tcgtggcagc ggcgcagcac acaagcgtgg ctgagcttcg
     4021 cgcccagata gtcgtcccgc agatcggcgt gggcgtcgaa atggacgatg tgcaggtcgg
     4081 ggtatttctt caccgcagca cgcaccgcac ccagcgtgac caaatgctcg ccgcccagca
     4141 gcagcgggaa cttgccgtcc ttcaggatct cctctgcccg ggcctcgata tcggacagtg
     4201 ccagctcgct ggagccgaag cacagctcca gatcgccgct gtcgaacaca tcaaaatcgg
     4261 tcaggtcggc gttctggtag gggctgtaag tctccagacc gtagctctcg tgccggacgg
     4321 ccgccgggcc gaaccgggcc cccgggcggt agctggtggt ggaatcgtag ggggcaccgt
     4381 acagcacgat gctggcggca cggtagctgc tgtcgcagcc gataaaggtt tcaacgttgg
     4441 ggtaaagcat cagtgttcct ccacttcccg cagcatctcc tccagaaaag ccggcaggta
     4501 gaatgctccg atatgcagtt tggtggtgta gtagcgggtg cgcatattca gcgccttcca
     4561 cgcttctgcg tccagatcat caatgggatg gtattttttg cttgcaaagc cgaacagcca
     4621 atagcccgcc gcaaaggtag ggatatgtgc ctgatacacc cggctgatgg ggaaggtgga
     4681 tgcaatgcgc ttgtggctgc gctgcatggc gctggcgtcc tcggcgtaga agggactgcc
     4741 ctgctggttg accatgatgc cgtcctcttt cagggcgttg aagcagctgc cgtagaactc
     4801 gcgggtgaac agaccctcag aggggccgaa ggggtcggag gagtccacga tgatgaggtc
     4861 gtattcctcc tcgcagcggc ggatatactt cagggcgttc tcaaagtaga tatgcacccg
     4921 gcggtcatcc atacggcagg cattgccggg cagataggcg cggcaagcct ccaccacctg
     4981 cgggtccatc tccacaaggt cgatgcgctc cacacggtcg tagcgggtca gctcccgcac
     5041 cacgccgccg tctccggcgc cgatgaccag aatatcctta gcctccttat gcaccgccat
     5101 gggcacatgg acgatcattt catcgtagat gaactcgtcg cgctcggtca gcatcacgtt
     5161 gccgtccagc gtgagcaccc ggccgaactc cggggtctca aagatatcaa tgcgctgata
     5221 atcgctctgc ttggagtaga gctgcttgtt cacacgaatg ctgtgcttca catccggggt
     5281 gtgaaactct gaaaaccaaa attccatctc tttccctcct tatgccagaa cattcaggtg
     5341 caagatttcg gggtcctccg ggccagtcat gctgcagccc ttggccttgg cgtactcgat
     5401 gtagttcaag atctccttgg tgatgcgctc gccgggtgca aggatgggga tgcccggggg
     5461 atagcacatg acgaactcgc tgcacaccat gccctcggtc tcccgcaggg gcaggctctt
     5521 tttgggggcg tagaaagcct cctgcgggct ggcagccacc acggggtcga tgtattcctg
     5581 gctcagcaga cccgagccat cggtgcggta ccggcgcttg atctcagcca gcgcactgac
     5641 cagacgctcc acctcctgcg ggcggtcgcc gatggacagg taggcaagga tgttgccgat
     5701 atcgccgaac tcgatctgga tatcgtactc atcccgcagg atgtcgtaga cctcgatgcc
     5761 ggccagaccg atatccagcg tatggacgct gagcttggtg gtgtcgaaat caaagacgga
     5821 atcgccgttg cacagctcct tgccaaaggc atagtagccg cccacggcat tgatctcctc
     5881 gcgggcgtac tcggcaatgt ccgccacctg atggaacacc tgccgtcccc gcagcgccag
     5941 attgcggcgg gagatatcca gactggacat cagcaggtaa ctgccggagg tagtctgggt
     6001 caggttgatg atctgacgca cataccccgg gtgcacgttg ggaccgatga gcagcaggct
     6061 ggactgggtc aggctgccgc cgctcttgtg catggacacc gaggccatat ctgcgcccgc
     6121 cgccatggca gaaaccggca ggccgccgcc aaagtagaag tgggtgccgt gggcttcatc
     6181 cgcaaggcag agcatcccgg cgtcgtgcgc catttttacg atggcacgca ggtcggagca
     6241 gatgccgtag taggtgggat tattcaccag cacagccaca gcgttggggt gctccttgat
     6301 ggccttggcc acctgctccc gcttcatgcc cagcgagatg cccagccgct tgtccacctc
     6361 gggattcaca tagaccggga ccgcgccgca gagcaccagc gcgttcagca cactgcggtg
     6421 cacgttgcgg ggcaggatga tctcatcgcc ccgcttgcag gctgtcagta ccatgctctg
     6481 cacagagctg gtggtgccgc ccaccattaa aaaggcgtgg gccgcgccaa aggcatcggc
     6541 ggccagctcc tcggcctccc ggatgaccga taccgggtgg cagagattat ccagcggctt
     6601 catgctgttc acgtccacac ccacgcactg ctggcccaga aaggccgtca gctccgggtt
     6661 gccgcggccc cgtttgtggc cgggcacatc aaaaggtacc acacgcatct gccggaactg
     6721 ctccagcgcc tcataaatgg gcgcgcggcg ctgatccagc cggaaccgtg tacggttctc
     6781 actcatcttt tctcctccgt ccctggttcc ggcgcagcaa aaaagcgcag gcccaccaca
     6841 ctggtgcaga cctgcgcttg aaaaagcgtt ctgaacatgc agacaaagcc cccggtgaca
     6901 ctggggaaaa cctccgcatg gttcaaaaag acgggatgac gagagtcttt atagcaatta
     6961 cacttttact cctcttattg accgtttcac aagtctgcgc acgttctgcg caatttcatg
     7021 gttgtaaagg aaccaactta taaaatttga gcttcaaact caatcaataa tggcagcttg
     7081 cgccgccggt cggcagtgga cccggctgtc cgtatggcct tagccccgtt tgggcggtcc
     7141 cgagtaaatt gctttgaaaa gactctgcaa ggcggcgtct ctcaaaatca acaaaagaat
     7201 aacatgattc gccccgtctg tcaaccaaaa ctttttggca gtcgcccgct gcgggtgcgc
     7261 agggcggcgc tcggcgcgca aaatggggcg ttttgtgcaa aaaagcagat acccttcccg
     7321 ccgcagtatg ctataataaa ggaacaatga atggagaaag agggtgtatg gatggcactg
     7381 ccaatcgcca tcgtagagga ccaggcagca gatgcccggc ggctggaaga gctgctgcaa
     7441 cagcagctgc ccgaagccga gtgcacatgg tttacctgcg gagatgattt tctccgtgcc
     7501 gcagcagagc ccggcttata cgccgtggtg tttctggata tctgcatggc gggcaccaac
     7561 ggcatcgaga ccgcccgccg gctacgacag gccgacccgg aggtgctgat cgtattcgta
     7621 acttcctccc cggaatatgt atgggacgcc tttccggtgc accccttcga ttacctgctc
     7681 aaaccctacc agaaggaaaa attcgtgcac cttgccgccg agctgcggcg ggcgctgcgt
     7741 tgtaaggagc cggaactgga gatccgcatt gcccgccaaa gcattcagct gccgctgcgc
     7801 aaggtgctgt atgccattgc ccggaaccac tacgtcctta tcaccaccga ggatggtgag
     7861 taccgtgcca tgtgcagctt tgcgcagatc gaagaaaagc ttactgctct ggaaaacttt
     7921 atgagctgca accggggcgt tatcatcaac atggacaagg tgctgcggtt cggggaggac
     7981 tgcatcgaga tcctggacgg cacccgcctg ccggtacggc aaaaggataa atgcactctg
     8041 cttgcccact ttacacaata ccagttccgc cacatgcggc aggagctgca ctgaggaaag
     8101 gagcagccgc catggatctt gctctgttcg gccgttattt tctggatttt gcgctgctgt
     8161 atcccagcgc gtttctgtgt ctggcatccc tatgggaaaa gctgcgcacc cccaggcgca
     8221 ccgcctgcat cgctgccgga tgcatcaccc tgctgtgcat cggctgcgcc gcgctctgcg
     8281 ccgtgttcgg gctgaacagc aattctctcc tgcccgccat cgtgctggtc tccttctggc
     8341 tgctgcgctg gcgggtaacg ccggaagtga ccgtaagcca gaccgcgttt ctgttttcca
     8401 tctctgccgt gatgatggcg gtgtgttccc tgctgtcgac gctgctcaac gcccagaccg
     8461 agatctccaa cccacagacg gtctgccttg cctccacggc gctgctgcgg ctgggccttg
     8521 ccgcgatgct caccgtgctg ttctggttca ccgccgtgca gtggagccgg tggctgctgc
     8581 gggagtacag cggtgaagcc ttctggcagt ctgcgtggcc gctgcccgcc ctctatgccg
     8641 tttttctggt atactgtatg ccgctgaacc ccgccgtggt gctggtcggg cgactgaaga
     8701 tcatctcggt gctggcggtg tccatctcgc tgttcggcat ctttctgctg ctgtacgaga
     8761 tgtaccgcgt tgcccgggag tttacccgca atgcccggct ggaccgggaa aaccagctgc
     8821 tggccatgga atcccgccgg tacatggagt tacagaccta tctggacaac acacgccgtc
     8881 tgcggcacga cttccggcag catctgcatg tgattgccgg actgaccgag accgggcagc
     8941 tggaggagct gaaaagctat ctgcaccagt atgaaagcga actcagtgag caccgcccca
     9001 gcctgtgcgc caacgccgcc gtggatgcac tggccggata ttacgaccat gcagccgggc
     9061 aacagagcgt tcctgtggag tggaagctgg cactgcctcg gcagcttccc atgccggagg
     9121 ccgacctgtg caccattctg ggcaatctgc tggaaaacgc cctgcacgcc agccagaagc
     9181 tgccgccgga gcagcgccgg gtgcaggtga tggcgcagat gctcagtccc gccatgctgg
     9241 ggcttgtggt ggagaaccgt tacgacggca tgctgaaaaa gcagcagggt atcctgcact
     9301 ccaccaagca cgagggcacc ggcatcgggc tggtatctgc cgagacggta gtgcacaaat
     9361 ataacggcaa tctgcatttg gagaccgagg agcagatctt ccgggtgaat gttctgttaa
     9421 atctgtaacc accggcaggc caacgtgaaa gcgttcacaa aaaagcagcg ccgtcctttg
     9481 cagagaggtt tctctacgaa gggcggcgct gtattatttt tcaagcttct ccgtgctttt
     9541 ttgtgcggct tccagctcgt ccacccgctt ttgcagggcg gtgatcttat cgtccatttt
     9601 caaaaatgtc cagaccagaa cggccagcac cagcgcggga ggaacgacca tccacaggga
     9661 ctgctgacac cagagcagca gcgaatagcc gccgaataca gtaaaaataa atacggcaaa
     9721 cagacttgca gccagtacag caaaaaatcc catacagaaa gtctcctttc agttattctt
     9781 ccgtttcttc ctcgtccggg tccagctcaa tgctgaacac ggcttttttc agcttgccgc
     9841 agccctgcgc cttcaggccg gatttatacg gttcccccgc cagatacaag gcaaagcgtc
     9901 cctcgcacag cattccggca atgctggtac cggcagtgcc tacggtggtg tcggcggctt
     9961 catcggttgg cttggtgggc gtcagctccg caaggcttac ctcaaacagc tcactgccgt
    10021 ccaagtcagt ctccagcgta atgtgattgt cgtgccgctg gaacagtgcc ttgtcggagg
    10081 tctggggcgt gacggtgctc acggtgacca ccgccttgtc cccatcgatg cgggtgcgcc
    10141 cggcaggcag ggtggtgata tcccgcgcca tgatgtactc gatcacggtg tccagattgt
    10201 cgcttacgcc cagatagttg ggcaggttgt tcagggtatc gtagatcatg gaaaaagtcc
    10261 tccgtctgtg ttgtttcagt tacctgtatg gtatcacagg tcagggacag atgcaatatg
    10321 tgtgcgggcg gatgtcgcga gccgcgcaga aaaggaaccc gggtcgcggc tcccagcggc
    10381 tgcgtcgtgc cttgggcggc acgcgcatcc tgctggccgc agccccaaca gctcctccct
    10441 gtttctgccg ctggcagcgg tcgtcgctgt tgcacagggg ctttcccccg ccggactatt
    10501 cggcgggtcg atgctgttcg aatccaccct tgcagcccct tttgcaagac agataaaaca
    10561 gaaactccgg tacccattgg ataccggagt tcttggtggg cgcgggtgga ttacgcgagc
    10621 cgcgctgcta aaaacagccc actgggctgt ttttgcgctg tcttctgcga cagcgccgca
    10681 gctgttcgaa tccacccgct ctatgagttt agccttgtca caaaacaaaa acctcagcgc
    10741 acttgcatac gctgaggctt tttggtggag cgaagcaacc caaatccgaa ccattgccct
    10801 ctggggcatc tttggcggcg atttcatcga aagtgatggt ttttgtgccg tctttgtagt
    10861 tgaatgcaat caaaactttt tcatcataga gataaaccgc gttcacgaac gtgttgataa
    10921 gcgtttcccg gtggcttttc acgttcgggt cgagcttgcg gaagttggtg agccaaaatt
    10981 tcacaaattc tgcactgacc ttcggctttg ccagcttttc ttccgcgatg cggatctcca
    11041 gttccttctg ctgggcctcc aacttttcca agcgtccttt ggtcgagctg gtcaacacac
    11101 ctgcctgaat cgcatttaac agattctcga tgccgttctc tatatccttc atctgctttt
    11161 ccagcagggg cagcaccgtg ttctcctgtt cctgaagaat catcaccgca tccacgatgg
    11221 actggatact gtcatcgtca cgaatcatct tcatggtctc gttgactacc aaatcctcca
    11281 gccactcttt gcggacggtc tttttcttgc aggtcttggt gcgcttggca ttagcacatt
    11341 tataataatg gtggacgttc ttattccggc tcgttccgca ctcgccgaac atcattgcgc
    11401 cacacattcc acagaacagc ttggtcgtca acaaataatc gtcctccgct ttgtgcggag
    11461 ccggagcgcg gcggtttttg gcgattttat cctgcacact atcgaacagt tctttctcaa
    11521 tgataaccgg gatgctgtcc ggcatcacaa tgtccttaaa acggttctct ccgatatagc
    11581 gacgattcgt caataaagtt tgaatactat tataggtgaa cttctgattg cggttggtag
    11641 tcacatcgct gtcgttcagc cagttcatca attctttcat ggttgcgcca tcgttatacc
    11701 gctgaaaggc ttccactaca aagggagctt tcaaagggtc aatctggaag aacttttcct
    11761 cgtctaccgt atagccaatg ggaatcgtgc cgccgttgta cttgcccttc agaacattct
    11821 cggtcatgcc gcgaacgacc ttttcagaaa gttctgctga atagtattca gccatgccgg
    11881 tgagcatact cttgaccatg atacccgctg ggccttccga aatcggctcg gtggccgata
    11941 ccagcttgac gtggttccgc tccaactggt actcgtagtg tgccgaatca tagcggtttc
    12001 gggcaaagcg gtcgagtttc cagaccagca caatgtcaaa cagccgcttt tcgctgtcct
    12061 tgatcatctg ctgaaagtcc gggcggttgt cggtttttgc ggaaagggcg cggtcaatat
    12121 agtgcttgat gactgtgatg ccgttcttct ctgcataggc cgtgcactcg cgaatctggc
    12181 cttcgatgga ttcttcacgc tggttgtcgc tggaatagcg agcgtagatc acagcggtca
    12241 tggcaggcac ctcccattta tataacattg aacagtggag cgttctttct aagcaatgtt
    12301 tcgtataatg gatataccac attttgcgag aaaaagcaag atgttatttt cacttctgtg
    12361 cacactaaaa atatcccggt cattcctctg cgcccagcag acggaataat cgggatgttt
    12421 tgcctatggt gtcgttcttt tacaccgcct tgggctggtc tgtcggtttc ttctggggct
    12481 tcatacccca aaacacagcg ttcatggcca ccacaatgag ggccactacg cccatggaca
    12541 cccagaagcc cagatcaaga cccagccagt gggtggtgcc gaatacggtc atccaaagtt
    12601 cattccagtt catgggtttt cctcctttac agcagctcgc catagtggcg gacgtaggct
    12661 tttttcaggc tggtggcaag caccatatac agcaggatgc aggggatcag gtaggcaaag
    12721 taggccgcag gcagcgccac aaagcctagt gccgtgccaa agggggtaaa ggggatgatg
    12781 gtcagcaccg caatgccggt catggtcagc agggtcaccg gggcggaagc ccggctctgg
    12841 ataaacggca gcttgggggt gcggatcatg tggatgacca gcgtctggct ccacatggac
    12901 tctacgaacc atccggcttg gaacatcccg atgtactgtg cctgcatcag agccagctgt
    12961 gccccactgt aatgagccgc cagatcgttg aacagcacgc ccccggacac gaacagcggg
    13021 cagaacacga agtacatgaa aatatacgtt gtaaagtcga agatggagct ggtgggtccg
    13081 atccagatca taaagctgcc cacgctggaa gcatcccatt tccggggctt ggcgataaat
    13141 tcctcgtcca cgttatccca ggggatggcg gtgcaggaga ggtcgtagat gaggttcagg
    13201 aaaataaggt ggacgctcat catgggcagg aagggcagca gagccgaggc tgccagcacc
    13261 gagaacatat taccgaagtt ggagctggct gtcatcttga tgtacttgat catgttggcg
    13321 taggtcttgc ggccctcgat gatgccctgc tccagcacca tcaggtcttt ttccagcagg
    13381 atgatgtctg ccgattcctt ggctacgtcc acggcggtat ccaccgaaat gccgatatcg
    13441 gcggctttca tggcagcggc atcgttgatt ccgtccccca taaagcccac ggtatggccg
    13501 ttttcccgca ggacggacac cacccgtgcc ttctggtccg gggtcagctt ggcaaacacg
    13561 tcggtgctct ctgctgcccg ggcaagttct gcatcggaca tatgatccag atccgaaccc
    13621 agcagcatat tgcgcacctt cagccccacc tgcttgcaga tggtgcgggt gaccttgtcg
    13681 ttgtcgccgg tgaggatctt ggtggtcaca ccgtggtctt tcagtgcccg gatggcatcg
    13741 gcggtggact ccttgggcgg gtcgaggaag gcaagatagc ccagcagcac catgtcccgc
    13801 tcgtccttta cgccaaaggc gtccaccggg gaggggttgc ttttctgggc aatggccagc
    13861 acccggaagc ccttgtcgtt cagctcgtcc acggtatgca gaattttgct gcggagggca
    13921 tttgttaggg gttccaccct gccgtcctgc tccgcatagg cacagatgga caacatctcc
    13981 tctacggcac ctttcgtcac catctgggtc ttgccagcct tgtcctgcac cacggtagtc
    14041 agacggcggc gggtgaagtc gaagggaatc tcgtccacct tcacatagtt ttccgacagg
    14101 tccagcaggc gggagtctgc agtttcttcc tcctcggtct tgtggatgat ggcaagatcc
    14161 atcaggttct tgtatccggt ctgaaagtag ctgttcaggt aggcgtggcg cagcacgcga
    14221 gtgtcgtttt cgccgttgac gttcaagtga tattccagca ccaccttatc ctgtgtcaga
    14281 gtgccggtct tatcagtgca gaggatgtca atggcgccga agttctggat ggagttcagg
    14341 tttttcacga tggtctgctt tttgctcatg gaaaccgcgc ccttggcaag gcaggtggtc
    14401 acgatcatgg gcagcatctc cggtgtcaga cccacggcga tggagatgcc gaacaaaaag
    14461 gcttccagcc agtcgccctt ggtgatgccg ttgatgaaga acaccagcgg caccatgacc
    14521 atcataaagc ggatcagcac ccacgaaacg gcgttgaccc ccttggtgaa gctggtctct
    14581 accgcctccc cagccacggc agaggccatg gagccgaaga gggtctggtc gcccacgcag
    14641 actgccacgg cggtggcact gccggagatc acgttgctgc ccataaaggc gatgtcggtg
    14701 tagtcagtga cactgtcccg gggagcactg actagcgggg tcttttcaat aggttcgctc
    14761 tcgccggtca ggctggcctg actgacgaac aggtcctttg cctccagaat gcggacgtcc
    14821 gccgggatca tatcgcccgc cgagagatgc acgatatctc ccaccaccag atcgtccatg
    14881 gggatttcca ccttctcctg ctcccgccgg gtaaccatgc aggtggtggt gatcatggcc
    14941 agcagctttt ccgccgcgtt gccgctgcgg gattcctgca cgaaccgcag ggtgccggag
    15001 atgagcacca tggtcaggat gatcacgacc gtcagcgggt caaaatcctc cggcgcactg
    15061 cccagcaagg aaaaatacgg gaacaccata tccgtcatgg tggacaccag tgccagacag
    15121 aacagaatgg cggtaaaggg gttgacgaag gctcccgcca gacgctgcac cagcgatttc
    15181 tttttctcgt gggtcacttt gttgctgccg tatttggcac ggctggcggt cacggcatcc
    15241 tcatccagcc ctcggagggt ggtgcggaga ttcttcatca cctcgccctc ggggttggtg
    15301 gcggcga
//
