LOCUS       gnlProkkaNMBIKGBI_218   4745 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NMBIKGBI_218.
ACCESSION   gnlProkkaNMBIKGBI_218
VERSION     gnlProkkaNMBIKGBI_218
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:58:14
            Original ID  :: gnl|Prokka|NMBIKGBI_218
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4745
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4745
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2013:3785]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2014..3785
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..4745
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4745
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             3..902
                     /locus_tag="ctg218_1"
                     /transl_table=11
                     /translation="MDKPILTDSGGFQVFSLSGLRKIKEEGVYFQSHIDGHHIFMGPEE
                     SMQIQSNLGSTIAMAFDECPSSRADRTYIQNSVDRTTRWLERCKKKMQELNSLPDTVNP
                     HQMLFGINQGGVFADIRIEHAKRISELDLDGYAVGGLAVGETHDEMYYILDEVVPYLPE
                     NKPTYLMGVGTPANIIEAVDRGIDFFDCVYPSRNGRHGHVYTHHGKLNLFNKKFELDPR
                     PIEEGCQCPSCRTYSRAYIRHLLKAKEMLGMRLCVLHNLYFYNHLMEEIRGAIDEHRYK
                     EFKKTTLEGFLTPEEEYR"
     CDS             945..1178
                     /locus_tag="ctg218_2"
                     /transl_table=11
                     /translation="MTIRPQKKQQKAADEMHAGMQAGDSVLTTSGFYGVIIDIMDDTVI
                     VEFGNNRNCRIPMQKDAIAAVEKPNLTKTEEE"
     CDS             1534..1914
                     /locus_tag="ctg218_3"
                     /transl_table=11
                     /translation="MDGISYKKWMERAAGLFLSALIAVLLTMLFLAVFAFAMLKGNLSA
                     SVEKIGLIVMSVMACFVGGFLCGKKNMKKRYLWGLGVGVLYCLFFGVIRVGMGQAFVTD
                     TTAFFTMMLYCAAGGMLGGMLS"
     CDS             2014..2160
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_4"
                     /sec_met_domain="TIGR03973 (E-value: 2.3e-23, bitscore:
                     70.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1.2e-22, bitscore: 68.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVKTLTGNKTYGTTMCKGGCGECQTSCQSACKTSCTVGNQTCE
                     SNK"
     CDS             2421..3785
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg218_5"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 6.6e-34,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.9e-21, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             3786..4745
                     /locus_tag="ctg218_6"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVREMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIKEKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAGDGIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEAFLEIAAMATVCDVMPLCDENRIIVKEGLQRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQ"
ORIGIN
        1 gatgggataa accaatcctt accgattctg gcggatttca ggtgttttct ctgtcaggtc
       61 ttcgaaagat aaaggaagaa ggcgtatatt tccagtcaca tattgatgga catcatattt
      121 ttatgggacc ggaagaaagt atgcagattc agtctaatct tggttctacg attgcgatgg
      181 catttgatga atgtccttca agtcgggcag acagaaccta cattcagaat tctgttgaca
      241 gaacaacaag atggttagaa cgctgtaaaa aaaagatgca ggaattaaac agcctgccag
      301 ataccgtaaa tccacaccag atgttatttg gtattaatca gggtggtgtt tttgcggata
      361 tccgtatcga gcacgctaaa agaatcagtg agcttgattt agatggttat gcagttggcg
      421 gacttgcagt aggagagaca catgatgaga tgtactatat ccttgatgaa gttgttccgt
      481 atctgccgga aaataaacca acttacctta tgggtgtagg aaccccagca aatattattg
      541 aggcagttga cagaggaatc gacttctttg actgtgtata tccttccaga aatggaagac
      601 acggacatgt gtatacgcat catggaaagt taaatctttt taataagaag tttgaattag
      661 acccccgccc aatcgaggaa ggatgccagt gtccgtcatg tcggacatac agcagagcct
      721 atatcagaca cctgctcaag gcaaaagaga tgcttggaat gcgtctttgt gttcttcata
      781 acctgtattt ctataatcat ttaatggaag aaatacgtgg agcaattgat gaacaccgct
      841 acaaagagtt caaaaaaacc acattagaag gttttttgac accggaagaa gaataccggt
      901 aatatnnnnn nnnnntcatt ctttttggag cgattatcta ctttatgaca atccgtccac
      961 agaagaagca gcagaaagca gcagacgaga tgcatgcagg aatgcaggct ggagacagcg
     1021 tattgactac aagcggattc tatggcgtaa tcatcgacat catggatgac actgtaatcg
     1081 tagaatttgg taacaaccgt aactgcagaa tcccaatgca gaaagatgct attgcagcag
     1141 tggagaagcc aaatcttaca aagacagaag aagagtagtt tcggttagcg ggacagacga
     1201 aaaatgaaaa agcagatatc ctatatttgt gactctatca ctgcgggttg aatgttcgcc
     1261 tccgggttca cattcaatcc tcgctaaggc cacaaatata ggatatctgt tttttgctaa
     1321 attgaaagta ctctccagtt taacaaagac agaaattaag agaccgccaa tatataaaaa
     1381 atgcgcctta gagcaagctc ttaatgcgga cgagcattaa gagcgcagtg atacgaagca
     1441 ttttttatat attggcggtc tcttaatttc gtctcgcttg ttctaaacag agaacccttt
     1501 tcataggcta taaaaaagcc tttggtgcag cctatggatg gaatttcgta taaaaaatgg
     1561 atggagcgtg cagcaggcct gtttctttct gcattaattg cagtattact cacaatgcta
     1621 tttttagcag tgtttgcatt tgccatgttg aaaggtaatc tttccgcttc cgtagaaaaa
     1681 attggtttaa ttgttatgag tgtgatggct tgttttgtcg ggggattttt gtgtgggaaa
     1741 aagaatatga aaaaacggta tttatggggg cttggcgtag gtgttttata ttgcttgttt
     1801 tttggagtaa tacgcgtcgg gatggggcag gcatttgtga cagatacgac agcatttttt
     1861 acaatgatgc tttattgtgc ggcaggagga atgcttggag gaatgttaag ctaaaaagtt
     1921 cttttcttac gggagggttt gtgttataat aacctacaaa gtgtcatctt agatgcttta
     1981 catactagat catgaagtga ggaggcgtta ttaatgaaac gtgtaaagac actgaccgga
     2041 aacaaaactt acggtactac aatgtgtaaa ggtggatgtg gcgagtgcca gacatcctgc
     2101 cagtctgcct gcaagacatc ttgtacagta ggtaaccaga cttgcgagag taataaataa
     2161 ttagagagca caacaggaag aatgcttcct gatatatgct tgaagtaggg tgaactgtct
     2221 tttttgtcag ttcaccttat ctcttgtatg gaaaagtatg tttgcagaga ttactttatt
     2281 gtaagttgaa aatattgtat acaggaatgt tctgtattat atatctattt taaagttagc
     2341 aggacatatc ttcaaattaa aaatatattt tagaaaatta agtataaaaa ctataaaaga
     2401 aatagaaagg gatatttaac gtgattcacc agtataaaaa taatggatat aatattgtca
     2461 tggatgtgtg cagtggtgcc attcatgttg ttgatgatgt gacttatgat gtcattgctt
     2521 tatatgaaga aaaaagcttg gaagaaatag aaaatgaact ttcttacagc aaggaagata
     2581 ttgaggaagc atataaagag gtaacttctt taaaagaaga gggactttta tttacagaag
     2641 atatttacga agattatatt aaagaggtaa agagcagaaa gacagtagta aaggcacttt
     2701 gcctgcatat tgcacatgat tgtaatcttg cctgccgcta ctgttttgca gaagaaggag
     2761 agtataaagg acaccgtgaa cttatgagtg caaaggttgg aaaggctgcc cttgatttcc
     2821 ttgtagccaa ttctggaaac cgtcataatc ttgaagttga cttctttggc ggtgagccaa
     2881 caatgaactt cggtgttgta aaggaagttg tagaatatgg acgttctctt gaagaaaaac
     2941 ataacaaaca tttccgtttc actttgacaa ccaatggtgt gctgttaaat gacgagatta
     3001 tggaatttgc caataaagaa atggacaacg ttgttttaag tgtcgatgga cgtaaagaaa
     3061 tccatgatta catgcgtcct acaagaaatg gtaagccaag ctatgacctt atcatgccga
     3121 agtttattcg ttttgcagag tccagacatc agcagaaata ctatgtaaga ggaacattta
     3181 ccaatagaaa tcttgatttc tccaaagatg ttcttcatct tgcagactta ggatttgaac
     3241 agatttccat ggaaccagtt gttggacagc cagaagagcc atacgcaatt caggaaaaag
     3301 accttccaca gatttttgat gagtatgaca gacttgcaaa agaaatgatt aagagagaaa
     3361 aagcaggaaa aggctttaat ttcttccact ttatgattga ccttacaggt ggtccatgtg
     3421 tagcaaaaag actttccggc tgtggaagcg gaacagagta tttagcagta acaccgtggg
     3481 gagatttata tccttgccac cagtttgtag gagaagagaa attccttctt ggtaacgttt
     3541 ttgatggaat caagcgtacc gatatttgtg acgaattccg ttcctgcaac gtatacacaa
     3601 agaaaaaatg taaagactgt tttgcgagat tctactgtag cggcggctgt cctgcaaact
     3661 cttataattt ccatggaaca attgatgatt cttatgattt aagttgcgat atggagcgta
     3721 agagagtaga atgcgcaatt atgattaagg ctgcattagc agatacagaa ggcgaagaag
     3781 aatagatgga aaagtggttt atcgcttcaa aaagagcaga ttttaataaa attggtgaga
     3841 tatttcatat cagcccggta acggcgcgtc tgatgagaaa taggagctta acaacagtta
     3901 gggaaatgca gcgttatctt tatggctctc tgtctgattt atatgattct catcttttga
     3961 aagatgccga taagggagcg gaaatcataa aagagaagat agaaacaggc aaaaagattc
     4021 ggattatttc ggattatgat gtagatggtg tttcatcaaa ctatatttta tatcagggat
     4081 taaaacgctg tggtgcggat gttgattata agattcctga ccgtgtggaa gacggttatg
     4141 gaattaatga acatctgata gaaaaggcag caggggacgg aattgatacg attatcacct
     4201 gtgacaatgg aattgcggca gcagaacaga ttgcttatgg aaattcttta ggactcaccc
     4261 tgattgtgac agatcatcat gatattccgt ttcaaaggca agaagatgga agcatttctt
     4321 ataatttgcc gtcagccgct gccgttatta atccgaagca aaaagattgt ccgtatccat
     4381 ttgaaaatat atgcggagcg gttgttgtct acaagtttat tcaggtgctt tacgatttgt
     4441 ttggaattga ccgtagagaa agtgaagcat ttcttgagat tgcggcgatg gcaacagtat
     4501 gtgacgttat gccattgtgt gatgagaacc gtattatcgt aaaggaaggc ctgcaacgga
     4561 tacagcatac gaatattacc gggctgcaag ctttaattga ggcaaatcat cttgaagaaa
     4621 aaaagatatc ttcttatcac tttggattta ttctcggtcc gtgtattaat gcttccggtc
     4681 gtttgacctc tgcaaaagat gcgttagaac ttcttctatg cgaagataaa gaactttgca
     4741 ggcag
//
