## Wed Jul 10 20:51:46 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_934871805.1/GCA_934871805.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934871805.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_934871805.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
ALEKFNDC_00001	622312.ROSEINA2194_01813	8.94e-82	250.0	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
ALEKFNDC_00002	622312.ROSEINA2194_01813	3.82e-13	67.8	COG5464@1|root,COG5464@2|Bacteria,1UA0N@1239|Firmicutes,247X9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
ALEKFNDC_00003	622312.ROSEINA2194_01812	8.6e-257	704.0	29Z45@1|root,30M1S@2|Bacteria,1V5Q9@1239|Firmicutes,24J6X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00005	585394.RHOM_00905	4.53e-65	199.0	COG2315@1|root,COG2315@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain protein	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
ALEKFNDC_00006	478749.BRYFOR_05176	1.51e-222	626.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00007	622312.ROSEINA2194_00484	2.82e-206	605.0	COG0369@1|root,COG0534@1|root,COG0534@2|Bacteria,COG1151@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00008	585394.RHOM_02135	4.03e-137	395.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
ALEKFNDC_00009	483218.BACPEC_02964	1.24e-37	129.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,269QT@186813|unclassified Clostridiales	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ALEKFNDC_00010	585394.RHOM_02150	3.86e-81	242.0	COG1846@1|root,COG1846@2|Bacteria,1V6G0@1239|Firmicutes,24K11@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ohrR	-	-	-	-	-	-	-	-	-	-	-	MarR
ALEKFNDC_00011	585394.RHOM_01250	1.39e-160	466.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ALEKFNDC_00012	478749.BRYFOR_08058	2.25e-96	303.0	COG1396@1|root,COG1396@2|Bacteria,1VBK2@1239|Firmicutes,24N6F@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,TPR_8
ALEKFNDC_00013	478749.BRYFOR_08059	2.04e-134	395.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
ALEKFNDC_00014	478749.BRYFOR_08059	2.22e-40	145.0	COG0477@1|root,COG2814@2|Bacteria,1TZWA@1239|Firmicutes,24C48@186801|Clostridia	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
ALEKFNDC_00015	622312.ROSEINA2194_01504	7.44e-216	604.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	5.1.1.1	ko:K01775,ko:K02529	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_00016	622312.ROSEINA2194_01505	6.66e-298	822.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
ALEKFNDC_00017	622312.ROSEINA2194_01506	3.61e-242	674.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
ALEKFNDC_00018	622312.ROSEINA2194_01507	2.3e-295	810.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_00019	622312.ROSEINA2194_01508	1.62e-177	498.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_00020	622312.ROSEINA2194_01509	1.03e-285	796.0	COG0366@1|root,COG0366@2|Bacteria,1TSEA@1239|Firmicutes,248HJ@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
ALEKFNDC_00021	585394.RHOM_12765	1.82e-77	238.0	2E401@1|root,32YWY@2|Bacteria,1V9X1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00022	1449335.JQLG01000004_gene941	4.42e-16	76.3	COG1309@1|root,COG1309@2|Bacteria,1VGKF@1239|Firmicutes,4HQGM@91061|Bacilli	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_00023	1235802.C823_01683	1.82e-10	69.3	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia	186801|Clostridia	J	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
ALEKFNDC_00026	622312.ROSEINA2194_01515	0.0	921.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
ALEKFNDC_00027	140626.JHWB01000009_gene1666	1.38e-30	115.0	2E823@1|root,332G5@2|Bacteria,1VRKM@1239|Firmicutes,24FQ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00028	622312.ROSEINA2194_01517	3.78e-143	407.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia	186801|Clostridia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
ALEKFNDC_00029	622312.ROSEINA2194_01518	4.04e-205	569.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia	186801|Clostridia	O	feS assembly protein SufB	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
ALEKFNDC_00030	1280681.AUJZ01000012_gene1135	7.94e-19	82.4	2ED22@1|root,2ZVQM@2|Bacteria,1W3EW@1239|Firmicutes,256YE@186801|Clostridia,4BZ46@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00031	585394.RHOM_02440	5.36e-96	283.0	COG1451@1|root,COG1451@2|Bacteria,1UJII@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
ALEKFNDC_00032	411474.COPEUT_02877	8.21e-17	73.6	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
ALEKFNDC_00034	585394.RHOM_02455	1.51e-35	120.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00035	1408306.JHXX01000009_gene3377	1.46e-95	295.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,4BWSH@830|Butyrivibrio	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SH3_3
ALEKFNDC_00036	585394.RHOM_02460	0.0	1008.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
ALEKFNDC_00037	585394.RHOM_02465	0.0	1092.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
ALEKFNDC_00038	585394.RHOM_02470	0.0	1096.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
ALEKFNDC_00039	585394.RHOM_02475	2.69e-207	575.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia	186801|Clostridia	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
ALEKFNDC_00040	585394.RHOM_02480	1.84e-300	823.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
ALEKFNDC_00041	585394.RHOM_02485	8.69e-138	398.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
ALEKFNDC_00042	585394.RHOM_02490	4.44e-179	502.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
ALEKFNDC_00043	622312.ROSEINA2194_03472	6.05e-145	416.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
ALEKFNDC_00044	585394.RHOM_02500	4.51e-30	108.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ALEKFNDC_00045	585394.RHOM_02505	4.42e-181	508.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ALEKFNDC_00046	585394.RHOM_02510	1.4e-201	558.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ALEKFNDC_00047	585394.RHOM_02515	0.0	1234.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
ALEKFNDC_00048	585394.RHOM_02520	2.28e-66	202.0	COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,24MNA@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	glnB1	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
ALEKFNDC_00049	585394.RHOM_02525	1.25e-282	773.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia	186801|Clostridia	P	Ammonium Transporter	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
ALEKFNDC_00052	622312.ROSEINA2194_02734	3.92e-69	223.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00053	1235793.C809_00941	1.2e-19	82.4	COG5566@1|root,COG5566@2|Bacteria,1VK7Y@1239|Firmicutes	1239|Firmicutes	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
ALEKFNDC_00054	1200557.JHWV01000007_gene1997	2.3e-07	50.1	2EI2T@1|root,33BU7@2|Bacteria,1VP7V@1239|Firmicutes,4H63N@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00057	877420.ATVW01000028_gene175	9.57e-84	254.0	COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,248B3@186801|Clostridia,27JNC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
ALEKFNDC_00060	1444310.JANV01000028_gene1610	1.35e-32	139.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes,4HSW0@91061|Bacilli,1ZQE7@1386|Bacillus	91061|Bacilli	S	D5 N terminal like	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,Pox_D5
ALEKFNDC_00062	1392491.JIAE01000001_gene2210	3.78e-29	125.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
ALEKFNDC_00064	903814.ELI_0831	9.7e-20	84.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ALEKFNDC_00065	1095750.HMPREF9970_1658	1.2e-99	311.0	COG5044@1|root,COG5044@2|Bacteria,1VXKX@1239|Firmicutes,252J9@186801|Clostridia	186801|Clostridia	O	Rab GDP-dissociation inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00066	1095750.HMPREF9970_1659	6.81e-291	871.0	COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,1TY16@1239|Firmicutes,24A3H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,Pkinase
ALEKFNDC_00069	556261.HMPREF0240_04096	1.23e-16	75.1	COG5566@1|root,COG5566@2|Bacteria,1VK7Y@1239|Firmicutes,24SS6@186801|Clostridia,36MMH@31979|Clostridiaceae	186801|Clostridia	S	Mor transcription activator family	-	-	-	-	-	-	-	-	-	-	-	-	Mor
ALEKFNDC_00070	411483.FAEPRAA2165_02657	2.78e-47	158.0	COG3597@1|root,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,249YT@186801|Clostridia,3WKSA@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF697,MMR_HSR1
ALEKFNDC_00071	397287.C807_03073	1.23e-12	62.4	2EIY3@1|root,33CP9@2|Bacteria,1VN11@1239|Firmicutes,24W71@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00073	585394.RHOM_02535	0.0	1375.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ALEKFNDC_00074	585394.RHOM_02540	4.79e-124	356.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
ALEKFNDC_00076	622312.ROSEINA2194_01571	3.97e-102	303.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia	186801|Clostridia	I	Acyl-ACP thioesterase	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
ALEKFNDC_00077	585394.RHOM_02550	1.31e-158	449.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia	186801|Clostridia	S	S1, RNA binding domain	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
ALEKFNDC_00078	585394.RHOM_02555	3.88e-75	225.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia	186801|Clostridia	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
ALEKFNDC_00079	592026.GCWU0000282_001066	1.87e-06	47.8	2EI20@1|root,33BTH@2|Bacteria,1VQF2@1239|Firmicutes	1239|Firmicutes	S	Putative motility protein	-	-	-	-	-	-	-	-	-	-	-	-	YjfB_motility
ALEKFNDC_00080	585394.RHOM_02570	1.23e-161	466.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
ALEKFNDC_00081	585394.RHOM_14870	0.0	935.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia	186801|Clostridia	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
ALEKFNDC_00082	585394.RHOM_02575	8.72e-82	251.0	COG1922@1|root,COG1922@2|Bacteria,1V7RM@1239|Firmicutes,24HC8@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
ALEKFNDC_00083	622312.ROSEINA2194_01579	1.27e-141	407.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
ALEKFNDC_00084	585394.RHOM_02580	3.34e-246	677.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia	186801|Clostridia	QT	Psort location Cytoplasmic, score	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
ALEKFNDC_00085	585394.RHOM_02585	5.81e-139	397.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia	186801|Clostridia	D	cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
ALEKFNDC_00086	622312.ROSEINA2194_01582	1.05e-173	489.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
ALEKFNDC_00087	585394.RHOM_02595	2.2e-133	395.0	COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,248ZG@186801|Clostridia	186801|Clostridia	D	Peptidase, M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ALEKFNDC_00088	622312.ROSEINA2194_01585	4.94e-215	604.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ALEKFNDC_00089	622312.ROSEINA2194_01586	2.34e-46	155.0	COG5652@1|root,COG5652@2|Bacteria,1VF6Q@1239|Firmicutes,24QQ8@186801|Clostridia	186801|Clostridia	S	PFAM VanZ family protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
ALEKFNDC_00090	585394.RHOM_02610	7.05e-227	627.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ALEKFNDC_00091	1408323.JQKK01000025_gene1380	7.2e-71	225.0	2EN4B@1|root,33FSE@2|Bacteria,1VPF9@1239|Firmicutes,24SXK@186801|Clostridia,27NCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tim44,zinc_ribbon_2
ALEKFNDC_00092	585394.RHOM_02620	2.79e-211	596.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia	186801|Clostridia	L	virion core protein (lumpy skin disease virus)	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1
ALEKFNDC_00093	585394.RHOM_02625	1.64e-160	462.0	COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia	186801|Clostridia	S	bacterial-type flagellum-dependent swarming motility	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00094	585394.RHOM_02630	3.29e-42	153.0	COG1512@1|root,COG1512@2|Bacteria,1V8N5@1239|Firmicutes,24H2W@186801|Clostridia	186801|Clostridia	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
ALEKFNDC_00095	585394.RHOM_02635	2.15e-83	248.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
ALEKFNDC_00096	622312.ROSEINA2194_01595	5.23e-237	657.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
ALEKFNDC_00097	658086.HMPREF0994_00444	5.94e-29	108.0	COG2198@1|root,COG2198@2|Bacteria,1VG8R@1239|Firmicutes,24JZF@186801|Clostridia,27PU8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Hpt domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
ALEKFNDC_00098	585394.RHOM_02670	2.54e-73	227.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes	1239|Firmicutes	P	Probably functions as a manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
ALEKFNDC_00099	622312.ROSEINA2194_01607	6.33e-242	666.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia	186801|Clostridia	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
ALEKFNDC_00100	585394.RHOM_02740	0.0	2013.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia	186801|Clostridia	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
ALEKFNDC_00101	585394.RHOM_02755	7.79e-209	589.0	COG2206@1|root,COG2206@2|Bacteria,1UUCI@1239|Firmicutes,24CPS@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
ALEKFNDC_00102	585394.RHOM_02760	2.37e-90	284.0	COG3773@1|root,COG3883@1|root,COG3773@2|Bacteria,COG3883@2|Bacteria,1V02Q@1239|Firmicutes,24CZW@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2
ALEKFNDC_00103	622312.ROSEINA2194_04078	1.26e-268	737.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
ALEKFNDC_00104	585394.RHOM_02770	2.14e-199	553.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia	186801|Clostridia	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
ALEKFNDC_00105	585394.RHOM_02775	4.52e-262	719.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia	186801|Clostridia	C	acyl-CoA dehydrogenase	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
ALEKFNDC_00106	622312.ROSEINA2194_04075	2.29e-179	500.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
ALEKFNDC_00107	622312.ROSEINA2194_04074	1.41e-240	662.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
ALEKFNDC_00108	1384066.JAGT01000001_gene2174	7.26e-14	74.3	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1TTH2@1239|Firmicutes,258XS@186801|Clostridia,3WP03@541000|Ruminococcaceae	186801|Clostridia	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00109	1408324.JNJK01000020_gene3693	1.95e-19	93.2	COG4412@1|root,COG4412@2|Bacteria,1VJS1@1239|Firmicutes,24RVX@186801|Clostridia,27QA4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	M6 family metalloprotease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00110	622312.ROSEINA2194_00831	9.66e-94	278.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
ALEKFNDC_00111	622312.ROSEINA2194_00831	6.44e-99	291.0	COG4684@1|root,COG4684@2|Bacteria,1V2ZW@1239|Firmicutes	1239|Firmicutes	S	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
ALEKFNDC_00112	411462.DORLON_02376	1.86e-42	150.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,27WEW@189330|Dorea	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ALEKFNDC_00113	471875.RUMLAC_00910	1.13e-51	173.0	2BZT7@1|root,32WKQ@2|Bacteria,1VC6X@1239|Firmicutes,24PVX@186801|Clostridia,3WQZR@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
ALEKFNDC_00114	471875.RUMLAC_00909	2.15e-62	199.0	2BZT8@1|root,32W5F@2|Bacteria,1UGQC@1239|Firmicutes,24Q23@186801|Clostridia,3WPWU@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
ALEKFNDC_00115	585394.RHOM_13050	3.23e-13	63.5	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
ALEKFNDC_00116	585394.RHOM_13145	1.68e-144	411.0	COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,248Z3@186801|Clostridia	186801|Clostridia	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase
ALEKFNDC_00117	622312.ROSEINA2194_01453	3.37e-113	328.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
ALEKFNDC_00118	585394.RHOM_13135	0.0	1944.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
ALEKFNDC_00119	622312.ROSEINA2194_01455	1.88e-130	384.0	2DCHY@1|root,2ZE7V@2|Bacteria,1UMSB@1239|Firmicutes,25FCG@186801|Clostridia	186801|Clostridia	-	-	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
ALEKFNDC_00120	622312.ROSEINA2194_01457	4.45e-86	257.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia	186801|Clostridia	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
ALEKFNDC_00121	585394.RHOM_02240	9.79e-210	598.0	COG0739@1|root,COG1388@1|root,COG3583@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,COG3583@2|Bacteria,1TRWJ@1239|Firmicutes,24A2J@186801|Clostridia	186801|Clostridia	M	Peptidase, M23	-	-	-	-	-	-	-	-	-	-	-	-	G5,LysM,Peptidase_M23
ALEKFNDC_00122	622312.ROSEINA2194_01459	1.08e-274	755.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia	186801|Clostridia	M	Belongs to the EPSP synthase family. MurA subfamily	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
ALEKFNDC_00124	1256908.HMPREF0373_02800	5.92e-84	257.0	COG3619@1|root,COG3619@2|Bacteria,1VBGA@1239|Firmicutes,24KG3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
ALEKFNDC_00125	585394.RHOM_02270	9.66e-156	448.0	COG2206@1|root,COG2206@2|Bacteria,1TR95@1239|Firmicutes,25AZS@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_00126	585394.RHOM_02275	2.38e-273	749.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
ALEKFNDC_00127	585394.RHOM_02280	1.1e-277	769.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia	186801|Clostridia	T	Histidine kinase- DNA gyrase B	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_00128	585394.RHOM_02285	8.99e-157	440.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_00129	585394.RHOM_02290	3.14e-26	99.0	28TG6@1|root,2ZFQ4@2|Bacteria,1W51P@1239|Firmicutes,2575E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00130	622312.ROSEINA2194_01477	2.1e-110	322.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ALEKFNDC_00131	585394.RHOM_02305	0.0	909.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
ALEKFNDC_00132	397291.C804_00766	2.56e-231	697.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG2199@2|Bacteria,1VQTU@1239|Firmicutes,24D8M@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ALEKFNDC_00133	622312.ROSEINA2194_01481	1.82e-244	680.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
ALEKFNDC_00134	585394.RHOM_02315	7.31e-144	417.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia	186801|Clostridia	S	spore coat protein, CotS	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
ALEKFNDC_00135	585394.RHOM_02320	8.39e-137	409.0	28JT6@1|root,2Z9II@2|Bacteria,1V7ZW@1239|Firmicutes,24H3G@186801|Clostridia	186801|Clostridia	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
ALEKFNDC_00136	622312.ROSEINA2194_01484	0.0	1047.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ALEKFNDC_00137	622312.ROSEINA2194_01485	1.04e-50	161.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
ALEKFNDC_00138	585394.RHOM_02340	2.46e-44	144.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia	186801|Clostridia	J	S4 domain protein	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
ALEKFNDC_00139	622312.ROSEINA2194_01487	1.24e-51	164.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
ALEKFNDC_00140	622312.ROSEINA2194_01488	1.13e-53	173.0	2EFTM@1|root,32YR5@2|Bacteria,1VEV2@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
ALEKFNDC_00141	622312.ROSEINA2194_01489	2.92e-34	120.0	COG2919@1|root,COG2919@2|Bacteria,1VGPP@1239|Firmicutes,24R6M@186801|Clostridia	186801|Clostridia	D	septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
ALEKFNDC_00142	622312.ROSEINA2194_01490	5.33e-213	591.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
ALEKFNDC_00143	622312.ROSEINA2194_01491	6.75e-310	860.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia	186801|Clostridia	KT	stage ii sporulation protein e	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
ALEKFNDC_00144	585394.RHOM_02375	2e-162	476.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
ALEKFNDC_00145	585394.RHOM_02380	9.54e-101	294.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
ALEKFNDC_00146	585394.RHOM_02385	0.0	1014.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
ALEKFNDC_00147	1280688.AUJB01000008_gene509	1.61e-163	468.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3NI27@46205|Pseudobutyrivibrio	186801|Clostridia	P	PBP superfamily domain	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
ALEKFNDC_00148	515620.EUBELI_01885	8.29e-157	445.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,25ZFW@186806|Eubacteriaceae	186801|Clostridia	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
ALEKFNDC_00149	515620.EUBELI_01884	9.61e-150	426.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,25VWA@186806|Eubacteriaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
ALEKFNDC_00150	515620.EUBELI_01883	1.49e-168	481.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,25W0F@186806|Eubacteriaceae	186801|Clostridia	E	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
ALEKFNDC_00151	1216932.CM240_2791	2.74e-279	778.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,36EZ2@31979|Clostridiaceae	186801|Clostridia	C	fumarate reductase succinate dehydrogenase flavoprotein domain protein	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
ALEKFNDC_00152	515620.EUBELI_01895	3.76e-50	160.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,25X48@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
ALEKFNDC_00153	1121115.AXVN01000104_gene847	9.04e-198	552.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3Y143@572511|Blautia	186801|Clostridia	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
ALEKFNDC_00154	483218.BACPEC_01211	8.8e-279	777.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,26AXX@186813|unclassified Clostridiales	186801|Clostridia	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
ALEKFNDC_00155	585394.RHOM_02390	1.1e-49	174.0	COG2206@1|root,COG2206@2|Bacteria,1V6IE@1239|Firmicutes,24K4Y@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_00156	585394.RHOM_02390	1.81e-151	454.0	COG2206@1|root,COG2206@2|Bacteria,1V6IE@1239|Firmicutes,24K4Y@186801|Clostridia	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_00157	622312.ROSEINA2194_01501	0.0	1142.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
ALEKFNDC_00160	585394.RHOM_12785	6.88e-187	543.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
ALEKFNDC_00161	585394.RHOM_12780	0.0	1127.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
ALEKFNDC_00162	585394.RHOM_01265	5.07e-165	467.0	2E1XD@1|root,32X6E@2|Bacteria,1VC0W@1239|Firmicutes,24P6H@186801|Clostridia	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
ALEKFNDC_00163	585394.RHOM_01325	4.6e-97	284.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
ALEKFNDC_00164	585394.RHOM_01330	1.49e-89	267.0	COG3247@1|root,COG3247@2|Bacteria,1VBAR@1239|Firmicutes,25CUJ@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
ALEKFNDC_00165	622312.ROSEINA2194_02398	7.27e-231	653.0	COG2199@1|root,COG2206@1|root,COG2199@2|Bacteria,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
ALEKFNDC_00166	622312.ROSEINA2194_02399	4.22e-41	135.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S7B@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00167	622312.ROSEINA2194_02400	6e-163	466.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_00168	585394.RHOM_01380	3.79e-106	309.0	COG1309@1|root,COG1309@2|Bacteria,1V44I@1239|Firmicutes,24I73@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_00169	1235802.C823_05083	0.0	1008.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,25UQF@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
ALEKFNDC_00170	585394.RHOM_01390	1.11e-127	412.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia	186801|Clostridia	J	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
ALEKFNDC_00171	585394.RHOM_01395	9.58e-88	263.0	COG1971@1|root,COG1971@2|Bacteria,1V9RZ@1239|Firmicutes,24KSZ@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	Mntp
ALEKFNDC_00172	622312.ROSEINA2194_02404	1.59e-289	811.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
ALEKFNDC_00173	622312.ROSEINA2194_02405	2.82e-95	285.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
ALEKFNDC_00174	585394.RHOM_01415	2.89e-59	191.0	2C456@1|root,32S3D@2|Bacteria,1VBI4@1239|Firmicutes,24N4Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00176	585394.RHOM_01425	4.07e-237	668.0	COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia	186801|Clostridia	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	G5,PG_binding_4,VanW
ALEKFNDC_00177	585394.RHOM_01430	8.5e-204	567.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia	186801|Clostridia	O	PFAM AIR synthase related protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
ALEKFNDC_00178	622312.ROSEINA2194_02409	7.69e-105	303.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, AsnC family	Lrp	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
ALEKFNDC_00179	585394.RHOM_01440	4.23e-266	730.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_00180	585394.RHOM_01445	2.06e-121	346.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
ALEKFNDC_00181	585394.RHOM_01450	3.84e-180	504.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
ALEKFNDC_00182	585394.RHOM_01455	6.02e-191	532.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
ALEKFNDC_00183	622312.ROSEINA2194_02414	9.99e-163	459.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
ALEKFNDC_00184	585394.RHOM_01465	8.64e-151	427.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
ALEKFNDC_00185	1415775.U729_2947	1.89e-36	129.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,24R64@186801|Clostridia,36NH8@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
ALEKFNDC_00186	1235798.C817_02114	1.51e-102	314.0	COG0515@1|root,COG0515@2|Bacteria,1V7U3@1239|Firmicutes,25AZB@186801|Clostridia	186801|Clostridia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
ALEKFNDC_00187	1235798.C817_02113	2.02e-17	74.3	2EJDK@1|root,33D4M@2|Bacteria,1VPVH@1239|Firmicutes,24VVZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
ALEKFNDC_00188	476272.RUMHYD_01730	1.5e-57	188.0	2DPEI@1|root,331RX@2|Bacteria,1VIYX@1239|Firmicutes,24REE@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
ALEKFNDC_00189	585394.RHOM_12405	9.81e-166	469.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
ALEKFNDC_00190	585394.RHOM_12410	1.42e-163	466.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00191	585394.RHOM_12415	5.44e-51	166.0	2DIZ6@1|root,32UC0@2|Bacteria,1VCGW@1239|Firmicutes,24Q40@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00192	585394.RHOM_12420	7.79e-65	200.0	2D61I@1|root,32TKA@2|Bacteria,1VB5H@1239|Firmicutes,24NZW@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	yvyF	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00193	585394.RHOM_12425	7.09e-77	240.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia	186801|Clostridia	S	ComF family	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
ALEKFNDC_00194	622312.ROSEINA2194_02619	5.92e-178	504.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
ALEKFNDC_00195	585394.RHOM_12435	6.4e-192	536.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
ALEKFNDC_00196	622312.ROSEINA2194_02621	1.41e-172	483.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
ALEKFNDC_00197	585394.RHOM_12445	0.0	1268.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
ALEKFNDC_00198	622312.ROSEINA2194_03005	1.54e-35	125.0	COG3951@1|root,COG3951@2|Bacteria,1VICK@1239|Firmicutes,24QXM@186801|Clostridia	186801|Clostridia	MNO	Flagellar rod assembly protein muramidase FlgJ	-	-	-	-	-	-	-	-	-	-	-	-	Rod-binding
ALEKFNDC_00199	585394.RHOM_12455	1.11e-139	400.0	COG4786@1|root,COG4786@2|Bacteria,1TT5Z@1239|Firmicutes,248M9@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02390,ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
ALEKFNDC_00200	585394.RHOM_12460	4.83e-151	429.0	COG4786@1|root,COG4786@2|Bacteria,1TRFQ@1239|Firmicutes,24C2V@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
ALEKFNDC_00201	585394.RHOM_12465	7e-221	611.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ALEKFNDC_00202	585394.RHOM_12045	1.55e-63	213.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_00203	585394.RHOM_12025	1.15e-72	236.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_00204	1123248.KB893314_gene3360	8.33e-62	202.0	COG0438@1|root,COG0438@2|Bacteria,4PN7G@976|Bacteroidetes,1J005@117747|Sphingobacteriia	976|Bacteroidetes	M	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
ALEKFNDC_00205	1469948.JPNB01000002_gene3304	9.14e-22	88.2	COG1396@1|root,COG1396@2|Bacteria,1VAEQ@1239|Firmicutes,24RMB@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_00206	585394.RHOM_12475	0.0	1771.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ALEKFNDC_00207	585394.RHOM_12480	0.0	1223.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
ALEKFNDC_00208	585394.RHOM_12610	3.31e-252	696.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia	186801|Clostridia	C	domain protein	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2
ALEKFNDC_00209	585394.RHOM_12615	0.0	1536.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
ALEKFNDC_00210	585394.RHOM_12620	2.17e-52	165.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
ALEKFNDC_00211	585394.RHOM_12625	6.39e-124	354.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia	186801|Clostridia	H	Dipicolinic acid synthetase, b subunit	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
ALEKFNDC_00212	585394.RHOM_12630	6.17e-145	415.0	COG0169@1|root,COG0169@2|Bacteria,1UHR5@1239|Firmicutes,25ETW@186801|Clostridia	186801|Clostridia	E	dipicolinic acid synthetase, A subunit	-	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,AdoHcyase_NAD,DpaA_N,IlvN
ALEKFNDC_00213	622312.ROSEINA2194_03033	3.55e-296	810.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
ALEKFNDC_00214	585394.RHOM_12645	3.57e-135	389.0	COG2908@1|root,COG2908@2|Bacteria,1TT6N@1239|Firmicutes,24A8X@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ALEKFNDC_00215	585394.RHOM_12650	1.38e-92	284.0	2C69W@1|root,2Z7HR@2|Bacteria,1TQNN@1239|Firmicutes,249G5@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4474)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4474
ALEKFNDC_00216	411470.RUMGNA_01046	2.54e-301	832.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
ALEKFNDC_00217	658655.HMPREF0988_01291	3.86e-130	378.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,25E9N@186801|Clostridia,27UHQ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	ARD,AraC_binding,Cupin_2,HTH_18
ALEKFNDC_00218	658088.HMPREF0987_02461	1.17e-167	472.0	COG1402@1|root,COG1402@2|Bacteria,1UDUM@1239|Firmicutes,2494R@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
ALEKFNDC_00219	658088.HMPREF0987_02460	7.06e-128	372.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
ALEKFNDC_00220	658088.HMPREF0987_02459	6.09e-266	736.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,27KBK@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
ALEKFNDC_00221	658088.HMPREF0987_02458	3.05e-108	325.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,24ISI@186801|Clostridia,27T9S@186928|unclassified Lachnospiraceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ALEKFNDC_00222	877415.JNJQ01000002_gene2280	1.31e-231	640.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,3VPNW@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Catalyzes the dehydration of D-mannonate	uxuA	-	-	-	-	-	-	-	-	-	-	-	UxuA
ALEKFNDC_00223	585394.RHOM_12655	3.54e-111	330.0	COG1388@1|root,COG1388@2|Bacteria,1V4FC@1239|Firmicutes	1239|Firmicutes	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ALEKFNDC_00224	585394.RHOM_12660	3.95e-124	358.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
ALEKFNDC_00225	585394.RHOM_12665	4.74e-51	164.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
ALEKFNDC_00226	622312.ROSEINA2194_03041	5.03e-191	546.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia	186801|Clostridia	CE	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
ALEKFNDC_00227	585394.RHOM_12675	6.15e-85	258.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
ALEKFNDC_00228	1235800.C819_03424	2.79e-173	495.0	COG0657@1|root,COG0657@2|Bacteria,1VUQV@1239|Firmicutes,250IT@186801|Clostridia,27UKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
ALEKFNDC_00229	658086.HMPREF0994_01172	3.3e-19	84.7	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
ALEKFNDC_00230	622312.ROSEINA2194_03055	1.63e-151	434.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia	186801|Clostridia	P	Belongs to the nlpA lipoprotein family	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
ALEKFNDC_00231	585394.RHOM_12805	9.38e-129	369.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia	186801|Clostridia	P	ABC-type metal ion transport system permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
ALEKFNDC_00232	622312.ROSEINA2194_03057	9.3e-180	508.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
ALEKFNDC_00234	622312.ROSEINA2194_03059	4.02e-189	528.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_00235	585394.RHOM_12825	4.14e-150	429.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
ALEKFNDC_00236	622312.ROSEINA2194_00531	9.66e-68	209.0	2E06E@1|root,32VUE@2|Bacteria,1VCMY@1239|Firmicutes,24NKQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00239	1504823.CCMM01000008_gene907	1.81e-153	439.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	yeiI	-	2.7.1.15,2.7.1.45,2.7.1.83	ko:K00852,ko:K00874,ko:K16328	ko00030,ko00240,ko01100,ko01120,ko01200,map00030,map00240,map01100,map01120,map01200	M00061,M00308,M00631	R01051,R01541,R02750,R03315	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_24,PfkB
ALEKFNDC_00240	411489.CLOL250_01422	6.32e-05	43.5	2EMZ1@1|root,33FM6@2|Bacteria,1VMDZ@1239|Firmicutes,24X8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00241	411489.CLOL250_01423	3.4e-235	652.0	COG0786@1|root,COG0786@2|Bacteria,1TQA4@1239|Firmicutes,247WX@186801|Clostridia,36EF4@31979|Clostridiaceae	186801|Clostridia	P	Catalyzes the sodium-dependent transport of glutamate	gltS	-	-	ko:K03312	-	-	-	-	ko00000,ko02000	2.A.27	-	-	Glt_symporter,NMT1_3
ALEKFNDC_00242	411489.CLOL250_01424	2.48e-122	360.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,36I0C@31979|Clostridiaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
ALEKFNDC_00243	585394.RHOM_12905	2.52e-316	866.0	COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K08659	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C69
ALEKFNDC_00244	140626.JHWB01000022_gene2128	2.64e-81	248.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ALEKFNDC_00245	622312.ROSEINA2194_00248	3.24e-261	723.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00246	622312.ROSEINA2194_00247	1.37e-228	637.0	COG4286@1|root,COG4286@2|Bacteria,1V2PW@1239|Firmicutes,248SR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	UPF0160
ALEKFNDC_00248	1487921.DP68_07245	5.19e-46	171.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
ALEKFNDC_00249	1031288.AXAA01000010_gene454	1.2e-07	57.8	COG0840@1|root,COG0840@2|Bacteria,1URS2@1239|Firmicutes,24B7E@186801|Clostridia,36H9N@31979|Clostridiaceae	186801|Clostridia	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ALEKFNDC_00251	1280698.AUJS01000065_gene671	1.16e-32	124.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
ALEKFNDC_00252	1280698.AUJS01000065_gene671	1.24e-72	234.0	COG4924@1|root,COG4924@2|Bacteria,1TRVG@1239|Firmicutes,24D0P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function N-terminus (DUF3323)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399,DUF3323
ALEKFNDC_00253	1280698.AUJS01000065_gene670	0.0	1653.0	COG1196@1|root,COG1196@2|Bacteria,1TPW9@1239|Firmicutes,247V7@186801|Clostridia	186801|Clostridia	D	Putative exonuclease SbcCD, C subunit	-	-	-	-	-	-	-	-	-	-	-	-	SbcCD_C
ALEKFNDC_00254	1280698.AUJS01000065_gene669	6.57e-219	610.0	28HUD@1|root,2Z813@2|Bacteria,1TUFV@1239|Firmicutes,24A4P@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2398
ALEKFNDC_00255	1280698.AUJS01000065_gene668	3.57e-285	789.0	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
ALEKFNDC_00257	1280671.AUJH01000002_gene1825	2.3e-39	154.0	COG2199@1|root,COG3706@2|Bacteria,1TSW8@1239|Firmicutes,249J7@186801|Clostridia,4C1VP@830|Butyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
ALEKFNDC_00258	622312.ROSEINA2194_02987	3.33e-144	409.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia	186801|Clostridia	E	serine acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
ALEKFNDC_00259	585394.RHOM_11205	3.68e-313	856.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
ALEKFNDC_00260	585394.RHOM_11200	3.62e-85	252.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
ALEKFNDC_00261	585394.RHOM_11195	2.3e-161	454.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
ALEKFNDC_00262	622312.ROSEINA2194_02991	1.2e-90	272.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
ALEKFNDC_00263	585394.RHOM_11185	1.56e-308	842.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
ALEKFNDC_00264	585394.RHOM_11180	1.22e-66	229.0	2E03H@1|root,33IG6@2|Bacteria,1VKD9@1239|Firmicutes,24TED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00267	585394.RHOM_05035	2.05e-282	793.0	COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,2480C@186801|Clostridia	186801|Clostridia	M	PFAM sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ALEKFNDC_00268	622312.ROSEINA2194_00030	0.0	1011.0	COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,24BHM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA,YfhO
ALEKFNDC_00269	622312.ROSEINA2194_00032	6.35e-100	290.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia	186801|Clostridia	S	acyl-CoA thioester hydrolase, YbgC YbaW family	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
ALEKFNDC_00270	585394.RHOM_09960	0.0	1067.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia	186801|Clostridia	E	creatinase	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
ALEKFNDC_00271	585394.RHOM_09955	0.0	1439.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
ALEKFNDC_00272	622312.ROSEINA2194_00035	5.54e-93	276.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
ALEKFNDC_00273	585394.RHOM_09945	0.0	1014.0	COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,249Y7@186801|Clostridia	186801|Clostridia	D	cell division protein FtsA	ftsA	-	-	-	-	-	-	-	-	-	-	-	FtsA,MreB_Mbl
ALEKFNDC_00274	585394.RHOM_09940	3.45e-156	442.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia	186801|Clostridia	J	Metallo-beta-lactamase domain protein	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
ALEKFNDC_00275	585394.RHOM_09930	1.29e-50	161.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia	186801|Clostridia	T	Belongs to the UPF0237 family	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
ALEKFNDC_00276	585394.RHOM_09925	2.16e-300	822.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
ALEKFNDC_00277	585394.RHOM_09920	3.23e-137	405.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ALEKFNDC_00278	622312.ROSEINA2194_00040	2.45e-154	435.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia	186801|Clostridia	F	IMP cyclohydrolase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
ALEKFNDC_00279	585394.RHOM_09910	1.17e-268	737.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia	186801|Clostridia	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
ALEKFNDC_00280	622312.ROSEINA2194_00044	2.52e-134	400.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
ALEKFNDC_00281	585394.RHOM_09880	2.45e-254	701.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
ALEKFNDC_00282	622312.ROSEINA2194_00046	2.06e-94	278.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia	186801|Clostridia	S	acr, cog1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
ALEKFNDC_00283	585394.RHOM_09870	5.07e-39	129.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
ALEKFNDC_00284	585394.RHOM_09855	7.1e-80	246.0	COG5578@1|root,COG5578@2|Bacteria,1V91Z@1239|Firmicutes,24KZS@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
ALEKFNDC_00285	622312.ROSEINA2194_00049	1.1e-220	612.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
ALEKFNDC_00286	585394.RHOM_09845	1.51e-41	137.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ALEKFNDC_00287	622312.ROSEINA2194_00051	1.2e-129	372.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
ALEKFNDC_00288	585394.RHOM_09830	0.0	1575.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
ALEKFNDC_00289	622312.ROSEINA2194_00054	3.1e-199	555.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
ALEKFNDC_00290	585394.RHOM_09820	6.18e-265	728.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia	186801|Clostridia	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
ALEKFNDC_00292	585394.RHOM_09805	1.83e-62	193.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
ALEKFNDC_00293	622312.ROSEINA2194_00060	3.66e-271	748.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
ALEKFNDC_00294	622312.ROSEINA2194_00061	1.71e-49	157.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
ALEKFNDC_00295	585394.RHOM_09790	9.6e-38	127.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0109 family	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
ALEKFNDC_00297	622312.ROSEINA2194_00063	9.99e-98	286.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
ALEKFNDC_00298	622312.ROSEINA2194_00064	4.53e-145	412.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
ALEKFNDC_00299	585394.RHOM_09775	7.46e-72	216.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
ALEKFNDC_00301	411474.COPEUT_00135	8.9e-86	268.0	COG1670@1|root,COG3393@1|root,COG1670@2|Bacteria,COG3393@2|Bacteria,1V1G4@1239|Firmicutes,24G4Y@186801|Clostridia	186801|Clostridia	J	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
ALEKFNDC_00302	585394.RHOM_05295	2.66e-271	744.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia	186801|Clostridia	E	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_00303	1280694.AUJQ01000005_gene1348	1.58e-65	227.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3NGP7@46205|Pseudobutyrivibrio	186801|Clostridia	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,HisKA_7TM
ALEKFNDC_00304	140626.JHWB01000019_gene917	2.09e-24	103.0	COG2214@1|root,COG2214@2|Bacteria,1V4YZ@1239|Firmicutes,24U0J@186801|Clostridia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00305	457412.RSAG_01565	9.84e-131	372.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3WH3X@541000|Ruminococcaceae	186801|Clostridia	E	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
ALEKFNDC_00306	1173026.Glo7428_1322	7.56e-52	179.0	COG0657@1|root,COG0657@2|Bacteria,1G229@1117|Cyanobacteria	1117|Cyanobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
ALEKFNDC_00307	622312.ROSEINA2194_01130	9.3e-102	295.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
ALEKFNDC_00308	585394.RHOM_04995	1.52e-118	346.0	COG0775@1|root,COG0775@2|Bacteria,1TSB7@1239|Firmicutes	1239|Firmicutes	F	COG0775 Nucleoside phosphorylase	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
ALEKFNDC_00309	585394.RHOM_05430	4.18e-267	743.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia	186801|Clostridia	P	Abc transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
ALEKFNDC_00310	622312.ROSEINA2194_01127	2.74e-152	431.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
ALEKFNDC_00312	585394.RHOM_05440	5.11e-219	606.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
ALEKFNDC_00313	585394.RHOM_05445	1.45e-108	321.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
ALEKFNDC_00314	585394.RHOM_05450	1.21e-219	612.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ALEKFNDC_00315	585394.RHOM_05455	6.5e-269	738.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
ALEKFNDC_00316	585394.RHOM_05460	4.54e-45	145.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
ALEKFNDC_00317	585394.RHOM_05465	5.57e-254	703.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia	186801|Clostridia	J	MiaB-like tRNA modifying enzyme	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
ALEKFNDC_00318	622312.ROSEINA2194_01033	1.4e-53	168.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
ALEKFNDC_00319	622312.ROSEINA2194_01034	1.59e-86	256.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
ALEKFNDC_00320	622312.ROSEINA2194_01035	2.38e-36	124.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
ALEKFNDC_00321	585394.RHOM_05485	0.0	1020.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
ALEKFNDC_00322	622312.ROSEINA2194_01037	1e-47	155.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0342 family	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
ALEKFNDC_00323	585394.RHOM_05490	4.65e-55	178.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
ALEKFNDC_00324	622312.ROSEINA2194_01039	1.34e-123	355.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
ALEKFNDC_00325	622312.ROSEINA2194_01040	9.89e-281	769.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia	186801|Clostridia	O	peptidase U32	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
ALEKFNDC_00326	585394.RHOM_05505	1.13e-207	579.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
ALEKFNDC_00328	397291.C804_00768	1.42e-185	561.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,27ICQ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ALEKFNDC_00329	585394.RHOM_00590	2.5e-141	401.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_00330	585394.RHOM_13945	5.01e-263	728.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00331	585394.RHOM_00565	0.0	963.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
ALEKFNDC_00332	585394.RHOM_00560	1.36e-203	584.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,sCache_3_3
ALEKFNDC_00333	622312.ROSEINA2194_00437	1.34e-90	276.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
ALEKFNDC_00334	585394.RHOM_00550	5.24e-72	233.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia	186801|Clostridia	D	stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
ALEKFNDC_00336	585394.RHOM_00540	2.94e-186	520.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
ALEKFNDC_00338	642492.Clole_3044	4.9e-136	421.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1
ALEKFNDC_00339	622312.ROSEINA2194_00906	8.26e-275	757.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia	186801|Clostridia	S	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
ALEKFNDC_00340	622312.ROSEINA2194_00905	7.77e-119	348.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
ALEKFNDC_00341	622312.ROSEINA2194_00904	3.72e-149	424.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia	186801|Clostridia	L	hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
ALEKFNDC_00343	1235800.C819_00145	3.9e-07	58.5	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZH@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
ALEKFNDC_00344	585394.RHOM_00490	2e-44	159.0	2ANQY@1|root,31DQM@2|Bacteria,1V7FM@1239|Firmicutes,24MF6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00345	585394.RHOM_00485	7.38e-124	375.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00346	585394.RHOM_00480	0.0	1201.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
ALEKFNDC_00347	1340434.AXVA01000004_gene2641	2.79e-06	58.5	COG1653@1|root,COG3757@1|root,COG4733@1|root,COG1653@2|Bacteria,COG3757@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	lyc	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17,3.2.1.8	ko:K01181,ko:K01185,ko:K02027,ko:K07273,ko:K07451,ko:K17315,ko:K17318	ko02010,map02010	M00207,M00603,M00605	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02048	3.A.1.1,3.A.1.1.24,3.A.1.1.29,3.A.1.1.30,3.A.1.1.9	-	-	Glyco_hydro_25,LysM,Phage-tail_3
ALEKFNDC_00348	411462.DORLON_02607	7.65e-65	199.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
ALEKFNDC_00349	411462.DORLON_02608	3.73e-273	751.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
ALEKFNDC_00350	411462.DORLON_02609	2.29e-298	819.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea	186801|Clostridia	S	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
ALEKFNDC_00351	411462.DORLON_02610	3.47e-153	432.0	COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,248U5@186801|Clostridia	186801|Clostridia	G	Belongs to the MIP aquaporin (TC 1.A.8) family	glpF	-	-	ko:K02440	-	-	-	-	ko00000,ko02000	1.A.8.1,1.A.8.2	-	-	MIP
ALEKFNDC_00352	411462.DORLON_02611	0.0	989.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea	186801|Clostridia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
ALEKFNDC_00353	1280698.AUJS01000028_gene2292	8.95e-102	298.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,27VYY@189330|Dorea	186801|Clostridia	K	Glycerol-3-phosphate responsive antiterminator	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
ALEKFNDC_00355	622312.ROSEINA2194_01741	1.28e-103	304.0	COG2755@1|root,COG2755@2|Bacteria,1V3A9@1239|Firmicutes,24FYQ@186801|Clostridia	186801|Clostridia	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_00356	585394.RHOM_00450	2.47e-160	468.0	2A7KX@1|root,30WIW@2|Bacteria,1V536@1239|Firmicutes,24J38@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00357	585394.RHOM_00445	1.52e-50	163.0	2DPVJ@1|root,333JK@2|Bacteria,1VGI4@1239|Firmicutes,24R70@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zinc_ribbon_2
ALEKFNDC_00358	585394.RHOM_00440	3.41e-152	436.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
ALEKFNDC_00359	585394.RHOM_00435	4.15e-103	301.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
ALEKFNDC_00360	585394.RHOM_00425	0.0	1634.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia	186801|Clostridia	L	snf2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
ALEKFNDC_00361	585394.RHOM_00410	1.83e-216	608.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
ALEKFNDC_00362	622312.ROSEINA2194_04402	8.01e-127	365.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_00363	585394.RHOM_00400	0.0	902.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia	186801|Clostridia	P	Na Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
ALEKFNDC_00364	585394.RHOM_00395	3.7e-116	337.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
ALEKFNDC_00365	622312.ROSEINA2194_04399	1.05e-170	477.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
ALEKFNDC_00366	622312.ROSEINA2194_04398	9.06e-160	453.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia	186801|Clostridia	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ALEKFNDC_00367	622312.ROSEINA2194_04397	8.2e-160	452.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
ALEKFNDC_00368	622312.ROSEINA2194_04395	1.5e-140	407.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia	186801|Clostridia	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
ALEKFNDC_00369	411463.EUBVEN_01388	1.45e-299	842.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,25UWP@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ALEKFNDC_00370	585394.RHOM_00370	1.75e-109	321.0	COG2357@1|root,COG2357@2|Bacteria,1VDTE@1239|Firmicutes,24Q2S@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
ALEKFNDC_00371	585394.RHOM_00365	8.93e-230	643.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia	186801|Clostridia	S	Major Facilitator	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
ALEKFNDC_00372	622312.ROSEINA2194_04393	4.35e-112	336.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia	186801|Clostridia	I	Alpha beta	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
ALEKFNDC_00373	585394.RHOM_00355	3.83e-142	407.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ALEKFNDC_00374	585394.RHOM_00325	8.23e-128	372.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
ALEKFNDC_00375	622312.ROSEINA2194_00263	1.51e-50	171.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
ALEKFNDC_00376	203119.Cthe_3129	9.08e-77	243.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
ALEKFNDC_00377	585394.RHOM_00310	5.19e-196	551.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
ALEKFNDC_00378	585394.RHOM_00305	0.0	1205.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
ALEKFNDC_00379	1408323.JQKK01000024_gene1322	1.28e-09	55.8	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24UJT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00380	411459.RUMOBE_02697	4.24e-268	736.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ALEKFNDC_00381	411459.RUMOBE_02698	6.13e-130	372.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
ALEKFNDC_00382	411459.RUMOBE_02699	9.57e-218	603.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3XYUJ@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
ALEKFNDC_00383	411459.RUMOBE_02700	8.28e-95	280.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3Y18Q@572511|Blautia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
ALEKFNDC_00385	585394.RHOM_00275	7.17e-153	434.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ALEKFNDC_00386	1235793.C809_00086	3.48e-162	479.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,27J9G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	3.2.1.80	ko:K03332	ko00051,map00051	-	R00879	-	ko00000,ko00001,ko01000	-	-	-	Big_2,CW_binding_1,Cadherin-like,DUF1080,Flg_new,Glyco_hydro_32C,Glyco_hydro_32N
ALEKFNDC_00387	1226325.HMPREF1548_04993	4.28e-297	817.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,36FBK@31979|Clostridiaceae	186801|Clostridia	G	Sucrose phosphorylase	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	2.4.1.329,2.4.1.7	ko:K00690,ko:K21350	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
ALEKFNDC_00388	1449050.JNLE01000003_gene571	1.69e-140	404.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,36EZR@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_00389	1449050.JNLE01000003_gene570	1.72e-177	498.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,36DX1@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_00390	1449050.JNLE01000003_gene569	2.75e-229	643.0	COG2182@1|root,COG2182@2|Bacteria,1UIC9@1239|Firmicutes,2499Z@186801|Clostridia,36UQF@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_00391	397291.C804_04832	5.98e-266	824.0	COG3209@1|root,COG3693@1|root,COG5492@1|root,COG3209@2|Bacteria,COG3693@2|Bacteria,COG5492@2|Bacteria,1UHTC@1239|Firmicutes,248KD@186801|Clostridia,27K6N@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate family 9 binding domain-like	-	-	3.2.1.4,3.2.1.8	ko:K01179,ko:K01181	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM9_1,CBM_4_9,Glyco_hydro_10,Polysacc_deac_1,SLH
ALEKFNDC_00392	180332.JTGN01000009_gene4214	2.35e-44	165.0	COG3533@1|root,COG5492@1|root,COG3533@2|Bacteria,COG5492@2|Bacteria,1VTDU@1239|Firmicutes	1239|Firmicutes	N	Bacterial Ig-like domain (group 4)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Big_4
ALEKFNDC_00393	585394.RHOM_16635	1.51e-57	178.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
ALEKFNDC_00394	585394.RHOM_16640	8.85e-97	282.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
ALEKFNDC_00395	585394.RHOM_16645	4.62e-54	170.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
ALEKFNDC_00396	622312.ROSEINA2194_04343	1.66e-33	116.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
ALEKFNDC_00397	1123075.AUDP01000021_gene1398	5.25e-82	245.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,3WJCK@541000|Ruminococcaceae	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
ALEKFNDC_00398	585394.RHOM_16655	1.52e-156	441.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
ALEKFNDC_00399	483218.BACPEC_02910	7.56e-149	447.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,268D0@186813|unclassified Clostridiales	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
ALEKFNDC_00401	585394.RHOM_16660	2.33e-84	253.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia	186801|Clostridia	S	PFAM nucleoside recognition domain protein	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
ALEKFNDC_00402	622312.ROSEINA2194_04339	7.24e-231	654.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
ALEKFNDC_00403	585394.RHOM_16670	4.05e-104	305.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia	186801|Clostridia	S	membrane protein required for spore maturation	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
ALEKFNDC_00404	585394.RHOM_16680	7.75e-235	668.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
ALEKFNDC_00405	622312.ROSEINA2194_04330	5.62e-172	483.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
ALEKFNDC_00406	642492.Clole_0437	3.32e-153	435.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
ALEKFNDC_00407	642492.Clole_0436	2.66e-134	386.0	COG0600@1|root,COG0600@2|Bacteria,1UYCY@1239|Firmicutes,249RH@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
ALEKFNDC_00408	642492.Clole_0435	2.25e-59	197.0	COG0715@1|root,COG0715@2|Bacteria,1UYBA@1239|Firmicutes,24D4Q@186801|Clostridia	186801|Clostridia	P	TIGRFAM ABC transporter, substrate-binding protein, aliphatic	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,OmpA
ALEKFNDC_00409	642492.Clole_0434	3.99e-54	171.0	COG0347@1|root,COG0347@2|Bacteria,1V73J@1239|Firmicutes,24S5C@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
ALEKFNDC_00410	642492.Clole_0433	2.32e-49	159.0	COG0347@1|root,COG0347@2|Bacteria,1VASB@1239|Firmicutes,24J84@186801|Clostridia	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
ALEKFNDC_00411	642492.Clole_0432	2.57e-283	789.0	COG0154@1|root,COG0154@2|Bacteria,1TSAQ@1239|Firmicutes,2483V@186801|Clostridia	186801|Clostridia	J	PFAM Amidase	-	-	3.5.1.54	ko:K01457	ko00220,ko00791,ko01100,ko01120,map00220,map00791,map01100,map01120	-	R00005	RC02756	ko00000,ko00001,ko01000	-	-	-	Amidase
ALEKFNDC_00412	642492.Clole_0431	0.0	1904.0	COG0439@1|root,COG1984@1|root,COG2049@1|root,COG0439@2|Bacteria,COG1984@2|Bacteria,COG2049@2|Bacteria,1TPUN@1239|Firmicutes,24E9Y@186801|Clostridia	186801|Clostridia	EI	Allophanate hydrolase subunit 1	-	-	6.3.4.6	ko:K01941	ko00220,ko00791,ko01100,map00220,map00791,map01100	-	R00774	RC00378	ko00000,ko00001,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,CT_A_B,CT_C_D
ALEKFNDC_00413	642492.Clole_0430	5.79e-138	392.0	COG3665@1|root,COG3665@2|Bacteria,1UYE1@1239|Firmicutes,24DNP@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 1	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
ALEKFNDC_00414	642492.Clole_0429	4.55e-155	437.0	COG3665@1|root,COG3665@2|Bacteria,1TQQF@1239|Firmicutes,24DHT@186801|Clostridia	186801|Clostridia	S	TIGRFAM Urea carboxylase-associated protein 2	-	-	-	ko:K09967	-	-	-	-	ko00000	-	-	-	DUF1989
ALEKFNDC_00415	642492.Clole_0428	1.6e-79	247.0	COG2197@1|root,COG2197@2|Bacteria,1V7ZQ@1239|Firmicutes,25BMW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
ALEKFNDC_00416	1122915.AUGY01000071_gene4411	2.16e-40	148.0	COG0715@1|root,COG0715@2|Bacteria,1UY07@1239|Firmicutes,4HCR6@91061|Bacilli,26S7G@186822|Paenibacillaceae	91061|Bacilli	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
ALEKFNDC_00417	1380390.JIAT01000010_gene4706	8.53e-31	121.0	COG1335@1|root,COG1335@2|Bacteria	2|Bacteria	Q	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
ALEKFNDC_00418	622312.ROSEINA2194_00855	9.51e-23	88.2	2EJZ9@1|root,33DPV@2|Bacteria,1VQST@1239|Firmicutes,254M5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00419	397290.C810_01918	2.32e-109	329.0	COG5492@1|root,COG5492@2|Bacteria,1V4A5@1239|Firmicutes,24IM0@186801|Clostridia,27MBH@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
ALEKFNDC_00420	1414720.CBYM010000015_gene2999	2.2e-120	351.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,36DPF@31979|Clostridiaceae	186801|Clostridia	HP	ABC transporter	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
ALEKFNDC_00421	1414720.CBYM010000015_gene3000	2.48e-137	400.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,36EF1@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuG	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
ALEKFNDC_00422	1216932.CM240_2981	3.68e-139	404.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,24A8W@186801|Clostridia,36FH9@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	fhuB	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
ALEKFNDC_00423	1280689.AUJC01000005_gene667	7.71e-159	454.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia,36EU7@31979|Clostridiaceae	186801|Clostridia	P	Periplasmic binding protein	fhuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
ALEKFNDC_00424	290402.Cbei_2136	1.48e-89	279.0	COG2207@1|root,COG2207@2|Bacteria,1V0EE@1239|Firmicutes,25B24@186801|Clostridia,36FJY@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ALEKFNDC_00425	585394.RHOM_16690	1.27e-143	410.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
ALEKFNDC_00426	622312.ROSEINA2194_04328	4.33e-155	437.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia	186801|Clostridia	S	Methyltransferase	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
ALEKFNDC_00427	622312.ROSEINA2194_04327	1.29e-188	527.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia	186801|Clostridia	K	domain protein	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
ALEKFNDC_00428	622312.ROSEINA2194_04326	2.71e-197	552.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia	186801|Clostridia	L	'dna polymerase iii	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
ALEKFNDC_00429	622312.ROSEINA2194_04325	4.89e-82	244.0	COG1728@1|root,COG1728@2|Bacteria,1VF6M@1239|Firmicutes,24S6C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF327)	-	-	-	ko:K09770	-	-	-	-	ko00000	-	-	-	DUF327
ALEKFNDC_00430	622312.ROSEINA2194_04324	8.46e-96	284.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
ALEKFNDC_00431	622312.ROSEINA2194_04323	1.59e-207	591.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
ALEKFNDC_00432	622312.ROSEINA2194_04322	1.2e-94	289.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	DUF3305,NTP_transf_3
ALEKFNDC_00433	585394.RHOM_16730	1.8e-72	232.0	2EE0F@1|root,337V8@2|Bacteria,1VFWV@1239|Firmicutes,24SC3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00434	585394.RHOM_16735	2.65e-112	327.0	COG5340@1|root,COG5340@2|Bacteria,1USGA@1239|Firmicutes,24IEV@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
ALEKFNDC_00435	585394.RHOM_16745	3.86e-209	592.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
ALEKFNDC_00436	622312.ROSEINA2194_04317	3.25e-137	389.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia	186801|Clostridia	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
ALEKFNDC_00438	622312.ROSEINA2194_04314	1.87e-235	654.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
ALEKFNDC_00439	585394.RHOM_16765	2.37e-15	87.4	COG5386@1|root,COG5386@2|Bacteria,1V541@1239|Firmicutes	1239|Firmicutes	M	Cell surface protein	surfB1	-	-	-	-	-	-	-	-	-	-	-	NEAT,SLH
ALEKFNDC_00440	585394.RHOM_16785	4.32e-277	763.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00441	585394.RHOM_13430	5.71e-143	405.0	2DB6M@1|root,2Z7HS@2|Bacteria,1U8V8@1239|Firmicutes,249IN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2871
ALEKFNDC_00442	483218.BACPEC_02760	1.25e-80	241.0	COG1846@1|root,COG1846@2|Bacteria,1V3G1@1239|Firmicutes,24G8T@186801|Clostridia,26CGS@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
ALEKFNDC_00443	483218.BACPEC_02215	2.33e-149	420.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,269T7@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
ALEKFNDC_00444	483218.BACPEC_02216	6.18e-219	604.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,2685W@186813|unclassified Clostridiales	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
ALEKFNDC_00445	483218.BACPEC_02217	5.23e-278	764.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,26A6P@186813|unclassified Clostridiales	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
ALEKFNDC_00446	483218.BACPEC_02218	1.63e-137	393.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_00447	622312.ROSEINA2194_03190	1.21e-147	422.0	COG3886@1|root,COG3886@2|Bacteria,1VXNH@1239|Firmicutes,25G6T@186801|Clostridia	186801|Clostridia	L	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
ALEKFNDC_00448	585394.RHOM_09600	3.88e-252	694.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia	186801|Clostridia	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
ALEKFNDC_00449	585394.RHOM_09605	4.09e-167	473.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia	186801|Clostridia	S	radical SAM protein, TIGR01212 family	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
ALEKFNDC_00450	585394.RHOM_09610	3.79e-100	292.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
ALEKFNDC_00451	585394.RHOM_09615	5.25e-117	339.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia	186801|Clostridia	V	Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
ALEKFNDC_00452	585394.RHOM_09630	0.0	921.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia	186801|Clostridia	E	oligoendopeptidase, M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
ALEKFNDC_00453	585394.RHOM_09640	2.53e-117	355.0	28JJA@1|root,2Z9CD@2|Bacteria,1TPY4@1239|Firmicutes,24DSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00454	585394.RHOM_03580	7.12e-168	478.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
ALEKFNDC_00455	585394.RHOM_03570	1.05e-214	596.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ALEKFNDC_00456	585394.RHOM_03565	5.86e-220	610.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ALEKFNDC_00457	585394.RHOM_03560	0.0	887.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	araG_1	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
ALEKFNDC_00458	585394.RHOM_03555	4.55e-212	592.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
ALEKFNDC_00459	585394.RHOM_03550	4.23e-241	675.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
ALEKFNDC_00460	585394.RHOM_03545	5.95e-213	608.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
ALEKFNDC_00461	585394.RHOM_09645	0.0	931.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
ALEKFNDC_00462	585394.RHOM_09650	0.0	2831.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia	186801|Clostridia	E	'glutamate synthase	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
ALEKFNDC_00463	411462.DORLON_00146	1.27e-28	109.0	COG2364@1|root,COG2364@2|Bacteria,1V19X@1239|Firmicutes,24DJ8@186801|Clostridia,27VXU@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00464	411462.DORLON_00146	1.52e-19	86.7	COG2364@1|root,COG2364@2|Bacteria,1V19X@1239|Firmicutes,24DJ8@186801|Clostridia,27VXU@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00466	537007.BLAHAN_04922	1.86e-52	170.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,3Y0CK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
ALEKFNDC_00467	622312.ROSEINA2194_00096	1.91e-95	288.0	COG1266@1|root,COG1266@2|Bacteria,1V7EK@1239|Firmicutes,24KV5@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ALEKFNDC_00468	622312.ROSEINA2194_00090	0.0	1270.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia	186801|Clostridia	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), A subunit	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ALEKFNDC_00469	585394.RHOM_09675	0.0	1204.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia	186801|Clostridia	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ALEKFNDC_00470	585394.RHOM_09685	3.1e-220	612.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
ALEKFNDC_00471	585394.RHOM_09690	1.56e-255	702.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
ALEKFNDC_00472	1235793.C809_04227	6.49e-106	313.0	COG0300@1|root,COG0300@2|Bacteria,1TRP8@1239|Firmicutes,24DNY@186801|Clostridia,27N1X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
ALEKFNDC_00473	585394.RHOM_12890	9.42e-151	434.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
ALEKFNDC_00474	1235802.C823_04351	9.25e-61	203.0	COG0775@1|root,COG0775@2|Bacteria,1VCJY@1239|Firmicutes,24CRR@186801|Clostridia	186801|Clostridia	F	PFAM purine or other phosphorylase family 1	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
ALEKFNDC_00475	1235802.C823_02304	5.72e-83	247.0	COG0756@1|root,COG0756@2|Bacteria,1V5PP@1239|Firmicutes,24I3J@186801|Clostridia,25W99@186806|Eubacteriaceae	186801|Clostridia	F	dUTPase	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
ALEKFNDC_00476	585394.RHOM_09700	1.48e-209	583.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
ALEKFNDC_00477	585394.RHOM_09705	4.06e-124	357.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ALEKFNDC_00478	585394.RHOM_09710	7.84e-301	822.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
ALEKFNDC_00479	585394.RHOM_09715	2.79e-167	499.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
ALEKFNDC_00480	585394.RHOM_09720	3.3e-187	523.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_00481	585394.RHOM_09725	5.37e-57	179.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
ALEKFNDC_00482	622312.ROSEINA2194_00078	4.35e-208	580.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
ALEKFNDC_00483	622312.ROSEINA2194_00077	1.09e-145	418.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia	186801|Clostridia	L	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
ALEKFNDC_00484	622312.ROSEINA2194_00076	1.71e-55	175.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
ALEKFNDC_00485	585394.RHOM_09750	5.68e-49	157.0	COG2257@1|root,COG2257@2|Bacteria,1VF4R@1239|Firmicutes,24QSW@186801|Clostridia	186801|Clostridia	S	cytoplasmic domain of flagellar protein FhlB	flhB1	-	-	ko:K04061	-	-	-	-	ko00000,ko02044	-	-	-	Bac_export_2
ALEKFNDC_00486	585394.RHOM_09755	1.93e-197	577.0	28J8T@1|root,2Z93Y@2|Bacteria,1UZBP@1239|Firmicutes,24F5R@186801|Clostridia	186801|Clostridia	S	Flagellar hook-length control protein FliK	-	-	-	-	-	-	-	-	-	-	-	-	Flg_hook
ALEKFNDC_00487	622312.ROSEINA2194_00073	1.83e-134	386.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
ALEKFNDC_00488	1235790.C805_02231	2.57e-74	229.0	COG0681@1|root,COG0681@2|Bacteria,1UZ8V@1239|Firmicutes,25CN7@186801|Clostridia,25WUU@186806|Eubacteriaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
ALEKFNDC_00489	622312.ROSEINA2194_00072	5.56e-170	478.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
ALEKFNDC_00490	585394.RHOM_09770	7.62e-111	321.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ALEKFNDC_00491	585394.RHOM_05525	8.02e-238	656.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
ALEKFNDC_00492	1034345.CAEM01000003_gene1256	7.26e-20	91.7	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,2I49F@201174|Actinobacteria,4CUE6@84998|Coriobacteriia	84998|Coriobacteriia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,Response_reg
ALEKFNDC_00493	397287.C807_03866	4.83e-72	228.0	28S3E@1|root,2ZEF6@2|Bacteria,1V25C@1239|Firmicutes,24GTH@186801|Clostridia,27KYG@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00494	471875.RUMLAC_02383	1.14e-236	660.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3WHBW@541000|Ruminococcaceae	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
ALEKFNDC_00495	585394.RHOM_01185	3.61e-243	676.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ALEKFNDC_00496	411461.DORFOR_01502	3.05e-113	332.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,27WS8@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
ALEKFNDC_00497	585394.RHOM_01170	8.9e-124	357.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
ALEKFNDC_00498	742765.HMPREF9457_00204	2.28e-142	409.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,27VZT@189330|Dorea	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_00499	622312.ROSEINA2194_03509	1e-206	575.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ALEKFNDC_00500	622312.ROSEINA2194_03510	1.38e-213	595.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
ALEKFNDC_00501	622312.ROSEINA2194_03511	0.0	887.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
ALEKFNDC_00502	622312.ROSEINA2194_03512	1.06e-236	659.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
ALEKFNDC_00503	585394.RHOM_05520	5.87e-24	99.4	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia	186801|Clostridia	D	Sporulation integral membrane protein YtvI	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ALEKFNDC_00504	585394.RHOM_11975	2.14e-94	298.0	28PI9@1|root,2ZC8C@2|Bacteria,1V6ZI@1239|Firmicutes,24M4V@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
ALEKFNDC_00505	632245.CLP_3145	5.77e-97	293.0	COG0382@1|root,COG0382@2|Bacteria,1TRTB@1239|Firmicutes,24AQ0@186801|Clostridia,36E6F@31979|Clostridiaceae	186801|Clostridia	H	PFAM UbiA prenyltransferase	ubiA	-	-	-	-	-	-	-	-	-	-	-	UbiA
ALEKFNDC_00507	1123307.KB904364_gene1166	4.44e-76	255.0	COG1807@1|root,COG1807@2|Bacteria,1V11Z@1239|Firmicutes,4ISNZ@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
ALEKFNDC_00508	585394.RHOM_12075	1.46e-107	320.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1VABR@1239|Firmicutes,24F51@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
ALEKFNDC_00509	585394.RHOM_12040	2.44e-252	711.0	COG1132@1|root,COG1132@2|Bacteria,1TQAN@1239|Firmicutes,24BEK@186801|Clostridia	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00510	585394.RHOM_12035	4.76e-91	278.0	2DMX9@1|root,32U7V@2|Bacteria,1W0SU@1239|Firmicutes,24QVG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00511	585394.RHOM_12030	5.76e-120	348.0	COG1922@1|root,COG1922@2|Bacteria,1UIHR@1239|Firmicutes,25BDH@186801|Clostridia	186801|Clostridia	M	Belongs to the glycosyltransferase 26 family	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	CoA_binding_3,Glyco_tran_WecB
ALEKFNDC_00512	483218.BACPEC_02363	1.54e-293	819.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,268P3@186813|unclassified Clostridiales	186801|Clostridia	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ALEKFNDC_00513	585394.RHOM_12025	6.17e-114	341.0	COG3594@1|root,COG3594@2|Bacteria,1VJ6T@1239|Firmicutes,24UK1@186801|Clostridia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_00514	585394.RHOM_12015	5.71e-142	409.0	COG2207@1|root,COG2207@2|Bacteria,1V1FV@1239|Firmicutes,24887@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
ALEKFNDC_00515	585394.RHOM_12010	1.1e-235	649.0	COG1089@1|root,COG1089@2|Bacteria,1TQ9T@1239|Firmicutes,24863@186801|Clostridia	186801|Clostridia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
ALEKFNDC_00516	585394.RHOM_12005	4.97e-221	610.0	COG0451@1|root,COG0451@2|Bacteria,1TQV2@1239|Firmicutes,249R2@186801|Clostridia	186801|Clostridia	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
ALEKFNDC_00517	585394.RHOM_12000	2.01e-257	713.0	COG0836@1|root,COG1917@1|root,COG0836@2|Bacteria,COG1917@2|Bacteria,1TPC9@1239|Firmicutes,24908@186801|Clostridia	186801|Clostridia	M	PFAM Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
ALEKFNDC_00518	585394.RHOM_11965	5.86e-61	189.0	COG3682@1|root,COG3682@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
ALEKFNDC_00519	411490.ANACAC_02076	6.17e-07	57.4	COG4219@1|root,COG4219@2|Bacteria,1VV9S@1239|Firmicutes,250ED@186801|Clostridia	186801|Clostridia	KT	Peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00520	585394.RHOM_11955	2.45e-156	446.0	COG2333@1|root,COG2333@2|Bacteria,1UEY5@1239|Firmicutes,24E8K@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ALEKFNDC_00521	483218.BACPEC_02375	3.07e-205	577.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,2682F@186813|unclassified Clostridiales	186801|Clostridia	M	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
ALEKFNDC_00522	585394.RHOM_11950	0.0	1139.0	COG0463@1|root,COG1216@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
ALEKFNDC_00523	585394.RHOM_11945	7.2e-33	114.0	2E96G@1|root,333F2@2|Bacteria,1VHVR@1239|Firmicutes,24SE5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00524	585394.RHOM_11940	0.0	921.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
ALEKFNDC_00525	622312.ROSEINA2194_02504	3.1e-155	444.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
ALEKFNDC_00526	585394.RHOM_11930	1.51e-300	824.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
ALEKFNDC_00527	585394.RHOM_11925	1.27e-187	531.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
ALEKFNDC_00528	585394.RHOM_11920	7.28e-160	456.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase, group 2 family protein	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
ALEKFNDC_00529	585394.RHOM_11910	3.31e-175	505.0	2DSN8@1|root,33GRU@2|Bacteria,1VPDR@1239|Firmicutes,24PGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00530	585394.RHOM_11905	2.8e-203	582.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ALEKFNDC_00531	1408321.JNJD01000008_gene2040	2.03e-184	528.0	COG0603@1|root,COG0603@2|Bacteria,1V0EU@1239|Firmicutes,24BK5@186801|Clostridia,27KYX@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00532	1410628.JNKS01000072_gene1060	7.4e-158	457.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,27IMU@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	iHN637.CLJU_RS20420	Mur_ligase_C,Mur_ligase_M
ALEKFNDC_00533	585394.RHOM_11815	7.72e-281	772.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia	186801|Clostridia	L	ATPase related to the helicase subunit of the Holliday junction resolvase	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
ALEKFNDC_00534	585394.RHOM_11810	2.93e-299	817.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia	186801|Clostridia	EK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
ALEKFNDC_00535	585394.RHOM_11800	3.32e-90	270.0	2BYUV@1|root,307Y4@2|Bacteria,1V64G@1239|Firmicutes,24K9A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00536	622312.ROSEINA2194_03404	6.15e-170	479.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia	186801|Clostridia	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
ALEKFNDC_00537	622312.ROSEINA2194_03403	7.82e-129	369.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia	186801|Clostridia	K	domain protein	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ALEKFNDC_00538	585394.RHOM_11785	3.68e-293	807.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia	186801|Clostridia	EG	GerA spore germination protein	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
ALEKFNDC_00539	585394.RHOM_11780	4.76e-214	622.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25DGZ@186801|Clostridia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
ALEKFNDC_00540	622312.ROSEINA2194_03400	5.77e-71	222.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia	186801|Clostridia	S	stage ii sporulation protein r	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
ALEKFNDC_00541	397290.C810_01003	1.51e-71	218.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,27N6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF1934)	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
ALEKFNDC_00542	585394.RHOM_11895	1.62e-295	808.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia	186801|Clostridia	G	Alpha amylase, catalytic domain protein	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_N
ALEKFNDC_00543	585394.RHOM_11890	2.19e-143	410.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
ALEKFNDC_00544	585394.RHOM_00260	1.81e-278	766.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ALEKFNDC_00545	585394.RHOM_00265	5.54e-185	516.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ35@1239|Firmicutes,25BI3@186801|Clostridia	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ALEKFNDC_00546	1408312.JNJS01000004_gene2375	7.78e-170	476.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio	186801|Clostridia	I	Enoyl-CoA hydratase/isomerase	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
ALEKFNDC_00547	585394.RHOM_11880	4.76e-255	702.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia	186801|Clostridia	E	PFAM aminotransferase class I and II	yugH	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_00548	622312.ROSEINA2194_00542	2.04e-186	528.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
ALEKFNDC_00549	622312.ROSEINA2194_00543	2.32e-244	675.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
ALEKFNDC_00550	622312.ROSEINA2194_00544	1.84e-219	608.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_00551	585394.RHOM_11850	1.14e-19	93.2	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,25EFE@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ALEKFNDC_00552	1235790.C805_02060	1.57e-130	376.0	COG4555@1|root,COG4555@2|Bacteria,1UHYH@1239|Firmicutes,25E73@186801|Clostridia	186801|Clostridia	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
ALEKFNDC_00553	397290.C810_02286	6.62e-124	370.0	COG1668@1|root,COG1668@2|Bacteria,1TQNC@1239|Firmicutes,2489Z@186801|Clostridia,27I77@186928|unclassified Lachnospiraceae	186801|Clostridia	CP	ABC-2 family transporter protein	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,ABC2_membrane_3,Abi
ALEKFNDC_00554	622312.ROSEINA2194_02238	6.09e-120	353.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UXKB@1239|Firmicutes,24DXK@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ALEKFNDC_00555	585394.RHOM_07120	1.2e-195	545.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
ALEKFNDC_00556	585394.RHOM_07115	8.24e-164	459.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
ALEKFNDC_00557	622312.ROSEINA2194_00984	3.46e-48	162.0	COG1559@1|root,COG1559@2|Bacteria,1VF4Y@1239|Firmicutes,24RCQ@186801|Clostridia	186801|Clostridia	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	-	-	-	-	-	-	-	-	-	-	-	-	YceG
ALEKFNDC_00558	585394.RHOM_07105	7.12e-57	187.0	COG3064@1|root,COG3064@2|Bacteria,1V968@1239|Firmicutes,24KD3@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00559	585394.RHOM_07100	1.1e-32	117.0	2ECFD@1|root,336DM@2|Bacteria,1VHDX@1239|Firmicutes,24TE9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00560	622312.ROSEINA2194_00979	1.6e-133	384.0	COG1191@1|root,COG1191@2|Bacteria,1TP9K@1239|Firmicutes,248M0@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ALEKFNDC_00561	585394.RHOM_07090	3.96e-22	89.4	2E8TH@1|root,33348@2|Bacteria,1VJ8V@1239|Firmicutes,24SQI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00562	585394.RHOM_07085	4.4e-101	294.0	COG1871@1|root,COG1871@2|Bacteria,1V70X@1239|Firmicutes,24HH7@186801|Clostridia	186801|Clostridia	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
ALEKFNDC_00563	585394.RHOM_07080	1.03e-121	350.0	COG1776@1|root,COG1776@2|Bacteria,1UNKB@1239|Firmicutes,247MX@186801|Clostridia	186801|Clostridia	NT	Chemotaxis protein CheC, inhibitor of MCP methylation	cheC	-	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
ALEKFNDC_00564	585394.RHOM_07075	3.02e-79	238.0	COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia	186801|Clostridia	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ALEKFNDC_00565	585394.RHOM_07070	0.0	1070.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia	186801|Clostridia	T	Signal transducing histidine kinase homodimeric	cheA	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
ALEKFNDC_00566	622312.ROSEINA2194_00972	1.6e-190	536.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
ALEKFNDC_00567	622312.ROSEINA2194_00971	5.52e-87	265.0	COG5581@1|root,COG5581@2|Bacteria,1VCR9@1239|Firmicutes	1239|Firmicutes	M	Flagellar protein YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
ALEKFNDC_00568	1235790.C805_01994	6.5e-121	355.0	COG0455@1|root,COG0455@2|Bacteria,1TRZ5@1239|Firmicutes,24AIN@186801|Clostridia,25VBY@186806|Eubacteriaceae	186801|Clostridia	D	4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family	flhG	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	CbiA,ParA
ALEKFNDC_00569	585394.RHOM_07050	1.7e-193	549.0	COG1419@1|root,COG1419@2|Bacteria,1TSP7@1239|Firmicutes,249R1@186801|Clostridia	186801|Clostridia	N	PFAM GTP-binding signal recognition particle SRP54 G- domain	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
ALEKFNDC_00570	622312.ROSEINA2194_00968	0.0	1124.0	COG1298@1|root,COG1298@2|Bacteria,1TQBM@1239|Firmicutes,248F5@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
ALEKFNDC_00571	585394.RHOM_07040	9.6e-205	574.0	COG1377@1|root,COG1377@2|Bacteria,1TPRP@1239|Firmicutes,248N7@186801|Clostridia	186801|Clostridia	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401,ko:K13820	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1,Bac_export_2
ALEKFNDC_00572	622312.ROSEINA2194_00966	3.95e-136	390.0	COG1684@1|root,COG1684@2|Bacteria,1TRB2@1239|Firmicutes,24ECW@186801|Clostridia	186801|Clostridia	N	flagellar biosynthetic protein FliR	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
ALEKFNDC_00573	585394.RHOM_07030	6.88e-46	149.0	COG1987@1|root,COG1987@2|Bacteria,1VEHF@1239|Firmicutes,24QJR@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
ALEKFNDC_00574	585394.RHOM_07025	6.76e-119	349.0	COG1338@1|root,COG1338@2|Bacteria,1TPIE@1239|Firmicutes,2487C@186801|Clostridia	186801|Clostridia	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
ALEKFNDC_00575	622312.ROSEINA2194_00963	2.66e-37	130.0	COG3190@1|root,COG3190@2|Bacteria,1VCEI@1239|Firmicutes,25FCZ@186801|Clostridia	186801|Clostridia	N	Flagellar biosynthesis protein, FliO	-	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
ALEKFNDC_00576	585394.RHOM_07015	4.64e-76	227.0	COG2197@1|root,COG2197@2|Bacteria,1UIGG@1239|Firmicutes,25EMX@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
ALEKFNDC_00577	585394.RHOM_07010	6.25e-191	540.0	COG1776@1|root,COG1886@1|root,COG1776@2|Bacteria,COG1886@2|Bacteria,1TPT8@1239|Firmicutes,24821@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flin	fliN	-	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	CheC,FliMN_C
ALEKFNDC_00578	585394.RHOM_07005	3.2e-203	566.0	COG1868@1|root,COG1868@2|Bacteria,1TPTM@1239|Firmicutes,24AGV@186801|Clostridia	186801|Clostridia	N	flagellar motor switch protein FliM	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
ALEKFNDC_00579	585394.RHOM_07000	8.46e-67	208.0	2AHM3@1|root,317YZ@2|Bacteria,1V80Z@1239|Firmicutes,24M4F@186801|Clostridia	186801|Clostridia	S	Controls the rotational direction of flagella during chemotaxis	-	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
ALEKFNDC_00580	585394.RHOM_06995	5.78e-111	328.0	COG1360@1|root,COG1360@2|Bacteria,1V8KE@1239|Firmicutes,24GQQ@186801|Clostridia	186801|Clostridia	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
ALEKFNDC_00581	585394.RHOM_06990	6.43e-138	395.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia	186801|Clostridia	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
ALEKFNDC_00582	622312.ROSEINA2194_00956	4.58e-24	93.2	COG1582@1|root,COG1582@2|Bacteria	2|Bacteria	N	Flagellar protein (FlbD)	flbD	-	-	ko:K02385	-	-	-	-	ko00000,ko02035	-	-	-	FlbD
ALEKFNDC_00583	585394.RHOM_06985	5.3e-226	642.0	COG1749@1|root,COG1749@2|Bacteria,1UHS7@1239|Firmicutes,247ZT@186801|Clostridia	186801|Clostridia	N	basal body rod protein	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
ALEKFNDC_00584	585394.RHOM_06980	3.05e-55	176.0	2E35U@1|root,32Y5R@2|Bacteria,1VEH9@1239|Firmicutes,24R2S@186801|Clostridia	186801|Clostridia	N	TIGRFAM flagellar operon protein	flg	-	-	-	-	-	-	-	-	-	-	-	Flagellar_put
ALEKFNDC_00585	585394.RHOM_06975	4.43e-78	243.0	COG1843@1|root,COG1843@2|Bacteria,1VF85@1239|Firmicutes,24QKD@186801|Clostridia	186801|Clostridia	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD
ALEKFNDC_00586	585394.RHOM_06970	1.66e-88	286.0	COG3144@1|root,COG3144@2|Bacteria,1V4YB@1239|Firmicutes,24JMD@186801|Clostridia	186801|Clostridia	N	Flagellar hook-length control protein	fliK	-	-	ko:K02414	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_hook
ALEKFNDC_00587	585394.RHOM_06965	1.14e-106	318.0	28H98@1|root,2Z7M1@2|Bacteria,1TRE9@1239|Firmicutes,24F21@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MgtE_N
ALEKFNDC_00588	585394.RHOM_06960	1.36e-59	188.0	COG2882@1|root,COG2882@2|Bacteria,1VK96@1239|Firmicutes,24RWK@186801|Clostridia	186801|Clostridia	NOU	flagellar export protein FliJ	fliJ	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
ALEKFNDC_00589	622312.ROSEINA2194_00945	4.32e-270	744.0	COG1157@1|root,COG1157@2|Bacteria,1TP0R@1239|Firmicutes,25E6B@186801|Clostridia	186801|Clostridia	NU	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
ALEKFNDC_00590	585394.RHOM_06950	2.45e-52	178.0	COG1317@1|root,COG1317@2|Bacteria,1V7UQ@1239|Firmicutes	1239|Firmicutes	NU	Flagellar assembly protein FliH	-	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
ALEKFNDC_00591	585394.RHOM_06945	1.56e-213	593.0	COG1536@1|root,COG1536@2|Bacteria,1TP01@1239|Firmicutes,2480B@186801|Clostridia	186801|Clostridia	N	Flagellar motor switch protein flig	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
ALEKFNDC_00592	622312.ROSEINA2194_00942	2.04e-226	642.0	COG1766@1|root,COG1766@2|Bacteria,1TRK0@1239|Firmicutes,2498Q@186801|Clostridia	186801|Clostridia	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
ALEKFNDC_00593	622312.ROSEINA2194_00941	9.85e-41	137.0	COG1677@1|root,COG1677@2|Bacteria	2|Bacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
ALEKFNDC_00594	585394.RHOM_06925	2.14e-78	235.0	COG1558@1|root,COG1558@2|Bacteria,1V6NB@1239|Firmicutes,24JJW@186801|Clostridia	186801|Clostridia	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
ALEKFNDC_00595	622312.ROSEINA2194_00939	3.78e-58	183.0	COG1815@1|root,COG1815@2|Bacteria,1VEUZ@1239|Firmicutes,24RBE@186801|Clostridia	186801|Clostridia	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
ALEKFNDC_00596	622312.ROSEINA2194_00938	8.66e-155	462.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
ALEKFNDC_00597	622312.ROSEINA2194_00938	0.0	1187.0	COG0550@1|root,COG4465@1|root,COG0550@2|Bacteria,COG4465@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
ALEKFNDC_00598	622312.ROSEINA2194_00937	1.85e-144	420.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia	186801|Clostridia	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
ALEKFNDC_00599	585394.RHOM_06900	3.88e-233	657.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
ALEKFNDC_00600	622312.ROSEINA2194_00935	3.41e-95	282.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
ALEKFNDC_00601	622312.ROSEINA2194_00934	7.23e-137	395.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
ALEKFNDC_00602	585394.RHOM_06885	9.4e-100	294.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00603	585394.RHOM_06880	5.83e-252	714.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
ALEKFNDC_00604	585394.RHOM_06865	9.22e-46	149.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
ALEKFNDC_00605	622312.ROSEINA2194_00929	0.0	890.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia	186801|Clostridia	L	DNA helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ALEKFNDC_00606	585394.RHOM_06855	0.0	922.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
ALEKFNDC_00607	585394.RHOM_06850	2.2e-213	612.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
ALEKFNDC_00608	585394.RHOM_06845	3.1e-199	565.0	COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
ALEKFNDC_00610	622312.ROSEINA2194_00922	3.08e-33	117.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
ALEKFNDC_00611	585394.RHOM_06825	6.83e-88	261.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia	186801|Clostridia	P	PFAM Manganese containing catalase	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
ALEKFNDC_00612	1235798.C817_00759	1.61e-142	416.0	COG1332@1|root,COG1332@2|Bacteria,1V8JA@1239|Firmicutes,24IAY@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm5 family	csm5	-	-	ko:K19140	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
ALEKFNDC_00613	1235798.C817_00758	1.46e-118	350.0	COG1567@1|root,COG1567@2|Bacteria,1V4UZ@1239|Firmicutes,24IT6@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm4 family	csm4	-	-	ko:K19139	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
ALEKFNDC_00614	1235798.C817_00757	1.88e-98	292.0	COG1337@1|root,COG1337@2|Bacteria,1V3DM@1239|Firmicutes,24IQD@186801|Clostridia	186801|Clostridia	L	CRISPR-associated RAMP protein, Csm3 family	csm3	-	-	ko:K09002	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
ALEKFNDC_00615	1235798.C817_00756	1.86e-46	153.0	COG1421@1|root,COG1421@2|Bacteria,1VGBY@1239|Firmicutes,24R4K@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein, Csm2 family	csm2	-	-	ko:K19138	-	-	-	-	ko00000,ko02048	-	-	-	Csm2_III-A
ALEKFNDC_00616	1235798.C817_00755	0.0	929.0	COG1353@1|root,COG1353@2|Bacteria,1TRW5@1239|Firmicutes,24BI3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein, Csm1 family	csm1	-	-	ko:K07016	-	-	-	-	ko00000,ko02048	-	-	-	HD
ALEKFNDC_00617	1235798.C817_00754	1.67e-100	299.0	COG5551@1|root,COG5551@2|Bacteria,1V7VJ@1239|Firmicutes,24IY3@186801|Clostridia	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	cas6	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
ALEKFNDC_00618	633697.EubceDRAFT1_0116	5.32e-117	337.0	COG2184@1|root,COG2184@2|Bacteria,1TPUZ@1239|Firmicutes,248XF@186801|Clostridia,25W8Z@186806|Eubacteriaceae	186801|Clostridia	D	Fic/DOC family	fic	-	-	ko:K04095	-	-	-	-	ko00000,ko03036	-	-	-	Bro-N,Fic
ALEKFNDC_00619	622312.ROSEINA2194_02469	2.72e-51	162.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00620	622312.ROSEINA2194_02470	2.89e-131	380.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
ALEKFNDC_00621	585394.RHOM_03615	1.42e-221	612.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
ALEKFNDC_00622	585394.RHOM_03610	0.0	1998.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia	186801|Clostridia	L	DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
ALEKFNDC_00623	397291.C804_03982	0.0	1013.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,27K0D@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	pulA	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3372,PUD
ALEKFNDC_00624	1280676.AUJO01000012_gene3474	0.0	928.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,4BYXB@830|Butyrivibrio	186801|Clostridia	G	Alpha-amylase domain	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
ALEKFNDC_00625	537007.BLAHAN_05096	7.23e-312	880.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
ALEKFNDC_00626	457412.RSAG_02406	4.22e-35	130.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
ALEKFNDC_00627	610130.Closa_0870	2e-259	753.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,223W0@1506553|Lachnoclostridium	186801|Clostridia	G	hydrolase family 65 central catalytic	-	-	2.4.1.230,2.4.1.8	ko:K00691,ko:K04844,ko:K10231	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
ALEKFNDC_00628	180332.JTGN01000002_gene5510	1.54e-126	368.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_00629	180332.JTGN01000002_gene5509	9.27e-141	406.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_00630	610130.Closa_0867	1.56e-136	407.0	COG1653@1|root,COG1653@2|Bacteria,1TR0C@1239|Firmicutes,248RD@186801|Clostridia,221RJ@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
ALEKFNDC_00631	1382315.JPOI01000001_gene107	8.88e-83	261.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,4HBNT@91061|Bacilli,1WFIB@129337|Geobacillus	91061|Bacilli	K	helix_turn _helix lactose operon repressor	cytR	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
ALEKFNDC_00632	1280696.ATVY01000004_gene422	7.68e-99	292.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia,4BY5V@830|Butyrivibrio	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
ALEKFNDC_00633	585394.RHOM_03595	9.84e-171	480.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ALEKFNDC_00634	483218.BACPEC_01903	1.08e-265	733.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,2685U@186813|unclassified Clostridiales	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00635	622312.ROSEINA2194_02475	0.0	1420.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ALEKFNDC_00636	1458462.JNLK01000001_gene1937	3.31e-158	457.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,27K39@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
ALEKFNDC_00637	1458462.JNLK01000001_gene1936	0.0	1086.0	COG2206@1|root,COG3275@1|root,COG3292@1|root,COG2206@2|Bacteria,COG3275@2|Bacteria,COG3292@2|Bacteria,1UZN2@1239|Firmicutes,25EWN@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF_2,HAMP,HD,HD_5,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
ALEKFNDC_00638	411461.DORFOR_02222	1.45e-95	285.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,27VNB@189330|Dorea	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
ALEKFNDC_00639	411462.DORLON_02488	1.16e-157	447.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,27VGK@189330|Dorea	186801|Clostridia	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
ALEKFNDC_00640	622312.ROSEINA2194_04370	9.79e-159	463.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
ALEKFNDC_00641	585394.RHOM_11425	0.0	1404.0	COG1482@1|root,COG2723@1|root,COG1482@2|Bacteria,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
ALEKFNDC_00642	585394.RHOM_11430	3.1e-174	497.0	COG2755@1|root,COG2755@2|Bacteria,1TQG2@1239|Firmicutes,24A1G@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_00643	585394.RHOM_11435	1.01e-181	513.0	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia	186801|Clostridia	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_00644	585394.RHOM_11440	1.27e-248	682.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_00645	585394.RHOM_11445	2.41e-279	764.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia	186801|Clostridia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_00646	585394.RHOM_11450	8.65e-250	691.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
ALEKFNDC_00647	1410616.JHXE01000013_gene255	1.14e-161	458.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3NGCJ@46205|Pseudobutyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_00648	1469948.JPNB01000002_gene3876	3.3e-178	503.0	COG1175@1|root,COG1175@2|Bacteria,1TQHI@1239|Firmicutes,247ZB@186801|Clostridia,36HT0@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_00649	1280673.AUJJ01000009_gene3083	1.52e-236	664.0	COG1653@1|root,COG1653@2|Bacteria,1TS0C@1239|Firmicutes,249WW@186801|Clostridia,4BZ2U@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
ALEKFNDC_00650	1042156.CXIVA_08220	4.11e-71	213.0	2EEYC@1|root,338RR@2|Bacteria,1VJ7I@1239|Firmicutes,24WPS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00651	622312.ROSEINA2194_00759	2.14e-134	394.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ALEKFNDC_00652	585394.RHOM_15795	6.66e-93	288.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
ALEKFNDC_00653	585394.RHOM_15800	1.64e-52	170.0	2EHCT@1|root,33B4M@2|Bacteria,1UPNG@1239|Firmicutes	1239|Firmicutes	S	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
ALEKFNDC_00655	1235790.C805_03392	5.65e-22	88.2	2EIA7@1|root,33C1J@2|Bacteria,1VMCK@1239|Firmicutes,24W47@186801|Clostridia,25XQS@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF2508)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2508
ALEKFNDC_00656	585394.RHOM_15815	2.02e-68	211.0	COG1516@1|root,COG1516@2|Bacteria,1VD1Q@1239|Firmicutes,24PMH@186801|Clostridia	186801|Clostridia	NOU	Flagellar protein FliS	-	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
ALEKFNDC_00657	585394.RHOM_15820	1.07e-199	571.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	hag	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
ALEKFNDC_00658	585394.RHOM_15825	7.4e-41	134.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia	186801|Clostridia	D	cluster protein-associated redox disulfide domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
ALEKFNDC_00659	585394.RHOM_15830	4.79e-127	368.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
ALEKFNDC_00660	622312.ROSEINA2194_00751	1.54e-136	407.0	COG0515@1|root,COG0515@2|Bacteria,1V3N4@1239|Firmicutes,25B6W@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
ALEKFNDC_00662	585394.RHOM_15850	4.45e-297	826.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia	186801|Clostridia	M	family 18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
ALEKFNDC_00663	622312.ROSEINA2194_00744	1.6e-100	299.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia	186801|Clostridia	M	N-Acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
ALEKFNDC_00664	622312.ROSEINA2194_00743	0.0	1044.0	28ISF@1|root,2Z8RM@2|Bacteria,1TSK2@1239|Firmicutes,249Q2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00665	585394.RHOM_15865	0.0	1207.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
ALEKFNDC_00666	585394.RHOM_15870	0.0	1020.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
ALEKFNDC_00667	585394.RHOM_15875	3.08e-201	571.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
ALEKFNDC_00668	585394.RHOM_15890	0.0	1389.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia	186801|Clostridia	C	aconitate hydratase	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
ALEKFNDC_00669	585394.RHOM_15900	0.0	974.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ALEKFNDC_00670	585394.RHOM_15905	2.78e-156	439.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_00671	585394.RHOM_15910	2.92e-168	480.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
ALEKFNDC_00673	585394.RHOM_15935	2.81e-73	231.0	2C331@1|root,30RPK@2|Bacteria,1V3YF@1239|Firmicutes,24IF9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00674	622312.ROSEINA2194_00858	0.0	895.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
ALEKFNDC_00675	622312.ROSEINA2194_01478	1.39e-67	234.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
ALEKFNDC_00676	585394.RHOM_14940	0.0	1147.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
ALEKFNDC_00677	585394.RHOM_15950	4.53e-265	736.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
ALEKFNDC_00678	585394.RHOM_15955	2.9e-166	468.0	COG3639@1|root,COG3639@2|Bacteria,1TQ73@1239|Firmicutes,24AGQ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	phnE_2	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ALEKFNDC_00679	585394.RHOM_15960	5.11e-162	457.0	COG3639@1|root,COG3639@2|Bacteria,1TR1S@1239|Firmicutes,24A7G@186801|Clostridia	186801|Clostridia	P	phosphonate ABC transporter, permease protein PhnE	phnE_1	-	-	ko:K02042	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	BPD_transp_1
ALEKFNDC_00680	585394.RHOM_15965	2.4e-157	444.0	COG3638@1|root,COG3638@2|Bacteria,1TQG6@1239|Firmicutes,249GS@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
ALEKFNDC_00681	585394.RHOM_15970	1.07e-200	563.0	COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,24A3Q@186801|Clostridia	186801|Clostridia	P	ABC-type phosphate phosphonate transport system periplasmic component	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
ALEKFNDC_00682	585394.RHOM_15975	4.56e-165	469.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_00683	1226325.HMPREF1548_01833	1.03e-93	282.0	COG0496@1|root,COG0496@2|Bacteria,1TS2T@1239|Firmicutes,24BI5@186801|Clostridia,36F35@31979|Clostridiaceae	186801|Clostridia	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
ALEKFNDC_00684	585394.RHOM_00600	3.72e-91	280.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24HJP@186801|Clostridia	186801|Clostridia	V	vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_2,VanW
ALEKFNDC_00685	585394.RHOM_15990	1.3e-232	647.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
ALEKFNDC_00686	140626.JHWB01000022_gene2044	2.69e-293	812.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
ALEKFNDC_00687	140626.JHWB01000022_gene2043	3.49e-35	121.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia	186801|Clostridia	G	phosphocarrier, HPr family	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ALEKFNDC_00688	622312.ROSEINA2194_04380	0.0	996.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia	186801|Clostridia	G	Phosphotransferase System	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
ALEKFNDC_00689	622312.ROSEINA2194_04379	9.34e-177	497.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ALEKFNDC_00690	622312.ROSEINA2194_04378	1.48e-137	393.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia	186801|Clostridia	K	transcriptional regulator DeoR family	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
ALEKFNDC_00691	622312.ROSEINA2194_04377	4.64e-73	227.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24F4A@186801|Clostridia	186801|Clostridia	G	phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ALEKFNDC_00692	515620.EUBELI_20099	2.91e-147	416.0	COG0546@1|root,COG0546@2|Bacteria,1V7U6@1239|Firmicutes,24ACT@186801|Clostridia,25XDB@186806|Eubacteriaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ALEKFNDC_00693	585394.RHOM_03675	1.28e-83	250.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia	186801|Clostridia	S	stage V sporulation protein AC	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
ALEKFNDC_00695	59374.Fisuc_1259	1.79e-10	65.5	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
ALEKFNDC_00697	622312.ROSEINA2194_03062	2.72e-224	621.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25CDJ@186801|Clostridia	186801|Clostridia	C	3-dehydroquinate synthase	egsA	-	1.1.1.261	ko:K00096	ko00564,map00564	-	R05679,R05680	RC00029	ko00000,ko00001,ko01000	-	-	-	Fe-ADH_2
ALEKFNDC_00699	585394.RHOM_10215	0.0	966.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
ALEKFNDC_00700	585394.RHOM_03700	1.02e-141	405.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ALEKFNDC_00701	622312.ROSEINA2194_01879	2.73e-73	223.0	2E3N2@1|root,32YK7@2|Bacteria,1VEYM@1239|Firmicutes,24QJ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00702	1280698.AUJS01000100_gene153	3.72e-128	367.0	COG2039@1|root,COG2039@2|Bacteria,1TRRX@1239|Firmicutes,248T4@186801|Clostridia,27W6C@189330|Dorea	186801|Clostridia	O	Pyroglutamyl peptidase	pcp	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
ALEKFNDC_00703	585394.RHOM_03705	4.8e-80	265.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
ALEKFNDC_00704	585394.RHOM_03710	9.61e-136	407.0	COG0845@1|root,COG0845@2|Bacteria,1V96V@1239|Firmicutes,24BEV@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ALEKFNDC_00705	585394.RHOM_03715	1.16e-220	623.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,24AWU@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ALEKFNDC_00707	585394.RHOM_03725	1.25e-129	373.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_00708	585394.RHOM_03730	6.85e-116	337.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
ALEKFNDC_00709	411902.CLOBOL_06104	1.21e-112	331.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,24KJZ@186801|Clostridia,22041@1506553|Lachnoclostridium	186801|Clostridia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
ALEKFNDC_00711	478749.BRYFOR_07844	2.99e-73	238.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ALEKFNDC_00712	641112.ACOK01000097_gene867	1.84e-79	253.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia,3WK37@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ALEKFNDC_00713	585394.RHOM_10995	0.0	998.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
ALEKFNDC_00714	397291.C804_04887	0.0	1083.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27J28@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_00715	397291.C804_04823	2.35e-155	466.0	COG2972@1|root,COG2972@2|Bacteria,1TPUF@1239|Firmicutes,2491H@186801|Clostridia,27JGZ@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
ALEKFNDC_00716	585394.RHOM_05765	3.41e-174	509.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,247MJ@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
ALEKFNDC_00717	397291.C804_04825	0.0	982.0	COG1653@1|root,COG1653@2|Bacteria,1TQWF@1239|Firmicutes,24CWD@186801|Clostridia,27IIE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
ALEKFNDC_00718	397291.C804_04826	3.21e-193	540.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia,27KGJ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_00719	397291.C804_04827	9.53e-177	497.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,27KBY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_00720	1226325.HMPREF1548_05296	1.45e-200	565.0	COG3405@1|root,COG3405@2|Bacteria,1U1E1@1239|Firmicutes,24878@186801|Clostridia,36FZI@31979|Clostridiaceae	186801|Clostridia	G	family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
ALEKFNDC_00721	1280390.CBQR020000071_gene1456	0.0	908.0	2DB7A@1|root,2Z7KK@2|Bacteria,1TQ2C@1239|Firmicutes,4HFKE@91061|Bacilli,26S01@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
ALEKFNDC_00722	585394.RHOM_05745	3.57e-251	707.0	COG2755@1|root,COG2755@2|Bacteria,1TPYH@1239|Firmicutes,2486S@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Lipase_GDSL_2
ALEKFNDC_00723	1163671.JAGI01000002_gene2603	1.4e-245	689.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,36ES1@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
ALEKFNDC_00724	585394.RHOM_10990	1.67e-180	509.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
ALEKFNDC_00725	622312.ROSEINA2194_04213	1.03e-250	696.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
ALEKFNDC_00726	622312.ROSEINA2194_04214	0.0	880.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_00727	622312.ROSEINA2194_04215	4.2e-181	506.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_00728	622312.ROSEINA2194_04216	0.0	1264.0	2DBG1@1|root,2Z91R@2|Bacteria,1TQV4@1239|Firmicutes,24CK0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00729	622312.ROSEINA2194_04217	6.33e-50	157.0	2EAM1@1|root,334PP@2|Bacteria,1VI13@1239|Firmicutes,24ST8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00730	622312.ROSEINA2194_04218	2e-204	567.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
ALEKFNDC_00731	622312.ROSEINA2194_04219	0.0	1746.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_00732	483218.BACPEC_02145	4.27e-190	542.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1TSFE@1239|Firmicutes,25KM5@186801|Clostridia,26AZA@186813|unclassified Clostridiales	186801|Clostridia	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ALEKFNDC_00733	585394.RHOM_06150	0.0	900.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
ALEKFNDC_00734	1226325.HMPREF1548_02216	7.11e-121	350.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,36F9G@31979|Clostridiaceae	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
ALEKFNDC_00735	1123075.AUDP01000001_gene2395	6.31e-97	288.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
ALEKFNDC_00736	1121344.JHZO01000005_gene292	7.18e-70	230.0	COG2206@1|root,COG2206@2|Bacteria,1VV1Y@1239|Firmicutes,2502J@186801|Clostridia	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
ALEKFNDC_00737	585394.RHOM_03410	5.95e-58	197.0	COG3064@1|root,COG3064@2|Bacteria,1V52J@1239|Firmicutes,24HMZ@186801|Clostridia	186801|Clostridia	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00738	622312.ROSEINA2194_02476	1.41e-105	313.0	COG1011@1|root,COG1011@2|Bacteria,1UIG9@1239|Firmicutes,25EMR@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
ALEKFNDC_00739	585394.RHOM_03400	4.73e-101	301.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ALEKFNDC_00740	585394.RHOM_03395	4.44e-69	212.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia	186801|Clostridia	F	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
ALEKFNDC_00741	622312.ROSEINA2194_02480	2.01e-42	141.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia	186801|Clostridia	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
ALEKFNDC_00742	585394.RHOM_03385	1.56e-228	640.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
ALEKFNDC_00743	622312.ROSEINA2194_02482	1.32e-20	82.4	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,24UDV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00744	585394.RHOM_03375	3.25e-191	546.0	COG1315@1|root,COG1315@2|Bacteria,1TR7W@1239|Firmicutes,24B18@186801|Clostridia	186801|Clostridia	L	PALM domain HD hydrolase domain and	-	-	-	ko:K09749	-	-	-	-	ko00000	-	-	-	FapA,Jag_N
ALEKFNDC_00745	585394.RHOM_03370	0.0	1730.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
ALEKFNDC_00746	585394.RHOM_03360	0.0	1453.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
ALEKFNDC_00748	585394.RHOM_03340	2.36e-171	482.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_00749	622312.ROSEINA2194_02493	1.01e-193	540.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_00750	585394.RHOM_03330	8.9e-267	739.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_00751	585394.RHOM_03325	1.47e-223	618.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia	186801|Clostridia	K	lacI family	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_00752	585394.RHOM_03320	0.0	1522.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia	186801|Clostridia	G	Glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
ALEKFNDC_00753	515620.EUBELI_00158	2.53e-164	463.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1V2SW@1239|Firmicutes,24GTR@186801|Clostridia,25XBA@186806|Eubacteriaceae	186801|Clostridia	K	COG2207 AraC-type DNA-binding domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
ALEKFNDC_00754	515620.EUBELI_00156	6.7e-253	702.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,25VVF@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00755	585394.RHOM_03315	0.0	957.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
ALEKFNDC_00756	622312.ROSEINA2194_04415	6.74e-200	556.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia	186801|Clostridia	E	carbamate kinase	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ALEKFNDC_00757	585394.RHOM_03305	8.81e-133	377.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
ALEKFNDC_00758	585394.RHOM_03300	0.0	1166.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
ALEKFNDC_00759	585394.RHOM_03295	6.72e-269	740.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
ALEKFNDC_00760	585394.RHOM_03290	6.78e-127	362.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ALEKFNDC_00761	585394.RHOM_03285	1.2e-254	706.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
ALEKFNDC_00762	397291.C804_02341	1.44e-77	244.0	COG0127@1|root,COG0127@2|Bacteria,1V85S@1239|Firmicutes,24KX4@186801|Clostridia,27NVI@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Ham1 family	-	-	-	-	-	-	-	-	-	-	-	-	Ham1p_like
ALEKFNDC_00763	511680.BUTYVIB_00807	1.47e-76	231.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,4BZAJ@830|Butyrivibrio	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
ALEKFNDC_00764	585394.RHOM_03230	0.0	1047.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00765	585394.RHOM_03220	0.0	905.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00766	1280698.AUJS01000061_gene1112	5.27e-100	296.0	COG1403@1|root,COG1403@2|Bacteria,1V5KT@1239|Firmicutes,24N2K@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00767	457421.CBFG_05938	8.07e-156	453.0	COG3950@1|root,COG3950@2|Bacteria,1UJJK@1239|Firmicutes,24CJD@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
ALEKFNDC_00768	665950.HMPREF1025_01293	1.23e-260	721.0	COG3385@1|root,COG3385@2|Bacteria,1TSH6@1239|Firmicutes,24A21@186801|Clostridia,27JSZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5,DDE_Tnp_1
ALEKFNDC_00769	585394.RHOM_14445	9.89e-66	203.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SseB
ALEKFNDC_00770	585394.RHOM_14420	1.44e-122	350.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
ALEKFNDC_00771	585394.RHOM_14415	7.6e-76	228.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ALEKFNDC_00772	585394.RHOM_13060	9.72e-100	318.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
ALEKFNDC_00773	622312.ROSEINA2194_01957	3.79e-96	294.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00774	585394.RHOM_14405	1.02e-76	235.0	COG1670@1|root,COG1670@2|Bacteria,1V1ZC@1239|Firmicutes,249K2@186801|Clostridia	186801|Clostridia	J	Acetyltransferase GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
ALEKFNDC_00775	585394.RHOM_14400	1.41e-97	285.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
ALEKFNDC_00776	1235790.C805_03317	2.21e-29	112.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,25XG3@186806|Eubacteriaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
ALEKFNDC_00777	585394.RHOM_14390	2.66e-223	617.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia	186801|Clostridia	C	phosphate acetyltransferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
ALEKFNDC_00778	585394.RHOM_14385	9.17e-256	709.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00779	622312.ROSEINA2194_04062	4.74e-157	449.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
ALEKFNDC_00780	457412.RSAG_02477	1.54e-270	751.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia	186801|Clostridia	P	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
ALEKFNDC_00782	1226322.HMPREF1545_00144	2.57e-42	156.0	COG0582@1|root,COG0582@2|Bacteria,1V16B@1239|Firmicutes,24CY2@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
ALEKFNDC_00783	622312.ROSEINA2194_03149	1.71e-108	314.0	COG4636@1|root,COG4636@2|Bacteria,1V4N9@1239|Firmicutes,24CZ1@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
ALEKFNDC_00784	742738.HMPREF9460_03849	2.35e-153	440.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,268S6@186813|unclassified Clostridiales	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
ALEKFNDC_00785	585394.RHOM_14345	1.31e-245	676.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ALEKFNDC_00786	622312.ROSEINA2194_00449	1.59e-316	869.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
ALEKFNDC_00787	585394.RHOM_14335	1.71e-47	155.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia	186801|Clostridia	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
ALEKFNDC_00788	622312.ROSEINA2194_04436	8.08e-162	455.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00789	397288.C806_01154	2.56e-90	269.0	COG0582@1|root,COG0582@2|Bacteria,1V2RX@1239|Firmicutes,24DD0@186801|Clostridia,27QUG@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
ALEKFNDC_00790	622312.ROSEINA2194_00548	4.4e-33	117.0	2ENS3@1|root,33GD8@2|Bacteria,1VQH1@1239|Firmicutes,24VFX@186801|Clostridia	186801|Clostridia	S	Global regulator protein family	-	-	-	-	-	-	-	-	-	-	-	-	CsrA
ALEKFNDC_00791	515620.EUBELI_00422	7.97e-129	392.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
ALEKFNDC_00792	397287.C807_02862	3.21e-66	223.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,27ND9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliB	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
ALEKFNDC_00793	1256908.HMPREF0373_01583	3.15e-51	162.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24MWS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
ALEKFNDC_00794	411463.EUBVEN_02075	2.76e-94	278.0	COG0406@1|root,COG0406@2|Bacteria,1V25J@1239|Firmicutes,24FZT@186801|Clostridia,25W5C@186806|Eubacteriaceae	186801|Clostridia	G	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ALEKFNDC_00795	622312.ROSEINA2194_00271	2.46e-121	350.0	COG2176@1|root,COG2176@2|Bacteria,1TRS5@1239|Firmicutes,24ER5@186801|Clostridia	186801|Clostridia	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	BRCT,RNase_T,zf-C4_Topoisom
ALEKFNDC_00796	140626.JHWB01000022_gene2109	3.94e-31	110.0	2ERQJ@1|root,33J9V@2|Bacteria,1VQ8Z@1239|Firmicutes,24VCG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00797	585394.RHOM_14945	4.12e-29	104.0	2E7J1@1|root,3321A@2|Bacteria,1VFYW@1239|Firmicutes,24RBB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00798	1280679.ATVX01000017_gene218	2.05e-36	125.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,4BZS5@830|Butyrivibrio	186801|Clostridia	C	Acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
ALEKFNDC_00799	742765.HMPREF9457_00412	2.3e-85	265.0	COG0834@1|root,COG0834@2|Bacteria,1VTCR@1239|Firmicutes,24YIS@186801|Clostridia,27WVQ@189330|Dorea	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
ALEKFNDC_00800	742765.HMPREF9457_00411	1.01e-147	468.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27WC0@189330|Dorea	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
ALEKFNDC_00801	585394.RHOM_14380	1.04e-173	488.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,24BGW@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
ALEKFNDC_00802	622312.ROSEINA2194_01965	2.94e-251	694.0	COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
ALEKFNDC_00803	585394.RHOM_14370	1.26e-133	383.0	COG2357@1|root,COG2357@2|Bacteria	2|Bacteria	S	guanosine tetraphosphate metabolic process	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
ALEKFNDC_00806	457421.CBFG_05476	2.62e-59	191.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,269B4@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF3793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
ALEKFNDC_00807	411469.EUBHAL_03045	4.2e-68	209.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,25WIN@186806|Eubacteriaceae	186801|Clostridia	C	flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
ALEKFNDC_00808	936574.HMPREF1508_1331	7.94e-41	135.0	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia	186801|Clostridia	S	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
ALEKFNDC_00809	1410628.JNKS01000004_gene2041	8.11e-73	219.0	COG3654@1|root,COG3654@2|Bacteria,1V6EG@1239|Firmicutes,24J85@186801|Clostridia,27NM5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TIGRFAM death-on-curing family protein	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
ALEKFNDC_00810	622312.ROSEINA2194_02915	3.68e-246	684.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_00811	622312.ROSEINA2194_00445	9.87e-54	171.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
ALEKFNDC_00812	622312.ROSEINA2194_00446	0.0	1226.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
ALEKFNDC_00813	180332.JTGN01000005_gene2749	3.05e-19	79.0	2EIM1@1|root,33CCB@2|Bacteria,1VM79@1239|Firmicutes,24UNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00814	622312.ROSEINA2194_04435	4.57e-130	371.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
ALEKFNDC_00815	585394.RHOM_14320	1.06e-193	538.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ALEKFNDC_00816	622312.ROSEINA2194_04433	1.83e-207	575.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ALEKFNDC_00817	622312.ROSEINA2194_04432	1.24e-106	333.0	COG1652@1|root,COG1652@2|Bacteria,1UIP6@1239|Firmicutes,25EPX@186801|Clostridia	186801|Clostridia	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
ALEKFNDC_00818	585394.RHOM_14305	1.22e-185	527.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00819	622312.ROSEINA2194_04430	1.61e-63	205.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24N5I@186801|Clostridia	186801|Clostridia	S	Colicin V production protein	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
ALEKFNDC_00820	903814.ELI_1175	3.05e-52	206.0	COG3209@1|root,COG3209@2|Bacteria,1UK8Y@1239|Firmicutes,24M4J@186801|Clostridia,25XIP@186806|Eubacteriaceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Flg_new,LRR_5
ALEKFNDC_00821	622312.ROSEINA2194_00234	2.56e-136	397.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
ALEKFNDC_00822	585394.RHOM_03155	1.05e-246	692.0	COG3507@1|root,COG3507@2|Bacteria,1TPHA@1239|Firmicutes,24AKT@186801|Clostridia	186801|Clostridia	G	family 43	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Dockerin_1,GH43_C,Glyco_hydro_43,Laminin_G_3
ALEKFNDC_00823	585394.RHOM_08550	1.06e-267	740.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
ALEKFNDC_00824	1121115.AXVN01000012_gene3113	1.6e-188	528.0	COG3940@1|root,COG3940@2|Bacteria,1TRHI@1239|Firmicutes,24AG6@186801|Clostridia,3Y1H0@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
ALEKFNDC_00825	140626.JHWB01000013_gene760	1.74e-293	809.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
ALEKFNDC_00826	1280688.AUJB01000008_gene632	5.67e-30	108.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24UPV@186801|Clostridia,3NIA5@46205|Pseudobutyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00827	1410625.JHWK01000005_gene1207	2.55e-170	481.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,27K27@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
ALEKFNDC_00828	622312.ROSEINA2194_02152	8.11e-61	191.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
ALEKFNDC_00829	585394.RHOM_02185	1.25e-101	307.0	COG2199@1|root,COG2199@2|Bacteria,1UV0N@1239|Firmicutes,24NW2@186801|Clostridia	186801|Clostridia	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
ALEKFNDC_00830	585394.RHOM_02190	0.0	1411.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia	186801|Clostridia	C	Glycine radical	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
ALEKFNDC_00831	622312.ROSEINA2194_02147	2.46e-134	386.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
ALEKFNDC_00833	585394.RHOM_02215	3.95e-109	315.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
ALEKFNDC_00834	622312.ROSEINA2194_03042	1.02e-142	410.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia	186801|Clostridia	T	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
ALEKFNDC_00836	622312.ROSEINA2194_02142	4.12e-207	578.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
ALEKFNDC_00837	622312.ROSEINA2194_02141	1.55e-254	708.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ALEKFNDC_00838	585394.RHOM_13125	1.6e-146	416.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia	186801|Clostridia	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
ALEKFNDC_00839	585394.RHOM_13120	2.53e-53	171.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
ALEKFNDC_00840	585394.RHOM_13115	1.26e-46	150.0	COG4466@1|root,COG4466@2|Bacteria	2|Bacteria	S	Protein conserved in bacteria	veg	-	-	-	-	-	-	-	-	-	-	-	VEG
ALEKFNDC_00841	585394.RHOM_13110	1.42e-227	644.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia	186801|Clostridia	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
ALEKFNDC_00842	585394.RHOM_13100	5.74e-103	320.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia	186801|Clostridia	M	NlpC p60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
ALEKFNDC_00843	585394.RHOM_13095	4.32e-80	239.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia	186801|Clostridia	S	YqeY-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
ALEKFNDC_00844	585394.RHOM_13085	2.97e-211	583.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia	186801|Clostridia	E	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
ALEKFNDC_00845	622312.ROSEINA2194_02128	2.8e-76	234.0	COG0344@1|root,COG0344@2|Bacteria,1V798@1239|Firmicutes,24KR2@186801|Clostridia	186801|Clostridia	I	Belongs to the PlsY family	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
ALEKFNDC_00846	622312.ROSEINA2194_02127	1.77e-176	502.0	COG0707@1|root,COG0707@2|Bacteria,1UQ6A@1239|Firmicutes,248FR@186801|Clostridia	186801|Clostridia	M	Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glycos_transf_1,MGDG_synth
ALEKFNDC_00847	33035.JPJF01000032_gene2185	2.39e-178	505.0	COG1609@1|root,COG1609@2|Bacteria,1TRWK@1239|Firmicutes,24DAV@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_00848	33035.JPJF01000032_gene2184	0.0	969.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
ALEKFNDC_00849	33035.JPJF01000032_gene2183	3.93e-269	744.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
ALEKFNDC_00850	33035.JPJF01000032_gene2182	2.43e-188	526.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
ALEKFNDC_00851	33035.JPJF01000032_gene2181	5.04e-159	450.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
ALEKFNDC_00852	33035.JPJF01000032_gene2180	0.0	951.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
ALEKFNDC_00853	1235800.C819_03126	2.51e-99	291.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,27TME@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
ALEKFNDC_00854	622312.ROSEINA2194_00591	0.0	1212.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia	186801|Clostridia	S	Myosin-crossreactive antigen	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
ALEKFNDC_00855	411470.RUMGNA_03147	8.65e-64	198.0	COG0454@1|root,COG0456@2|Bacteria,1VDD6@1239|Firmicutes,24NEN@186801|Clostridia,3Y0NK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ALEKFNDC_00856	622312.ROSEINA2194_01722	4.59e-206	570.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
ALEKFNDC_00857	622312.ROSEINA2194_01725	0.0	1281.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
ALEKFNDC_00858	585394.RHOM_16850	5.1e-146	418.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
ALEKFNDC_00859	585394.RHOM_16855	9.85e-144	417.0	COG2206@1|root,COG2206@2|Bacteria,1TQIM@1239|Firmicutes,248S5@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_00860	585394.RHOM_16860	4.28e-62	196.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
ALEKFNDC_00861	585394.RHOM_16865	6.14e-152	434.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia	186801|Clostridia	K	Belongs to the ParB family	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
ALEKFNDC_00862	585394.RHOM_16870	1.54e-167	469.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
ALEKFNDC_00863	585394.RHOM_16875	7.92e-109	318.0	COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia	186801|Clostridia	K	response regulator receiver	degU	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ALEKFNDC_00864	585394.RHOM_16880	1.56e-109	329.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
ALEKFNDC_00865	585394.RHOM_16885	2.74e-155	444.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
ALEKFNDC_00866	585394.RHOM_16890	2.79e-127	367.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
ALEKFNDC_00867	622312.ROSEINA2194_03228	0.0	1116.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
ALEKFNDC_00868	622312.ROSEINA2194_03229	6.78e-271	748.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
ALEKFNDC_00869	622312.ROSEINA2194_03230	1.05e-118	342.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
ALEKFNDC_00870	585394.RHOM_16915	1.01e-218	614.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
ALEKFNDC_00871	585394.RHOM_16925	3.33e-65	199.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
ALEKFNDC_00872	585394.RHOM_16930	3.25e-20	80.9	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
ALEKFNDC_00873	622312.ROSEINA2194_03235	9.39e-296	810.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
ALEKFNDC_00874	585394.RHOM_00010	3.22e-248	683.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
ALEKFNDC_00875	585394.RHOM_00015	1.54e-34	119.0	COG2501@1|root,COG2501@2|Bacteria	2|Bacteria	S	S4 domain	yaaA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
ALEKFNDC_00876	622312.ROSEINA2194_03238	3.05e-214	597.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
ALEKFNDC_00877	585394.RHOM_00025	0.0	1207.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
ALEKFNDC_00878	585394.RHOM_00030	0.0	1509.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
ALEKFNDC_00879	537007.BLAHAN_05724	1.05e-158	456.0	COG3550@1|root,COG3550@2|Bacteria,1UYFT@1239|Firmicutes,24C8G@186801|Clostridia,3Y2EV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00880	397291.C804_00163	3.21e-37	142.0	2DY23@1|root,347RM@2|Bacteria,1VQMX@1239|Firmicutes,24UP2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00881	397291.C804_00162	7.43e-57	193.0	COG1396@1|root,COG1396@2|Bacteria,1VC2K@1239|Firmicutes,24NMY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_00883	1211817.CCAT010000014_gene1390	1.06e-25	115.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
ALEKFNDC_00884	202954.BBNK01000014_gene2895	2.17e-12	75.1	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,1RMSR@1236|Gammaproteobacteria,3NJR0@468|Moraxellaceae	1236|Gammaproteobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
ALEKFNDC_00885	1280692.AUJL01000002_gene2728	7.45e-89	290.0	COG1132@1|root,COG1132@2|Bacteria,1V2WX@1239|Firmicutes,24GV7@186801|Clostridia,36R7T@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00886	1123075.AUDP01000012_gene3562	8.46e-53	171.0	COG3279@1|root,COG3279@2|Bacteria,1VEPW@1239|Firmicutes,24K2U@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
ALEKFNDC_00887	742740.HMPREF9474_01564	7.2e-53	171.0	2AH77@1|root,317H3@2|Bacteria,1V6I2@1239|Firmicutes,24KDW@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3021)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3021
ALEKFNDC_00888	658086.HMPREF0994_06595	0.0	1191.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,27JWP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 3 C-terminal domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	CBM_6,Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_00889	585394.RHOM_00040	1.06e-109	326.0	COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia	186801|Clostridia	S	NADP oxidoreductase coenzyme F420-dependent	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520,F420_oxidored,Rossmann-like
ALEKFNDC_00890	585394.RHOM_00045	6.66e-175	490.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
ALEKFNDC_00891	585394.RHOM_00050	3e-172	484.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
ALEKFNDC_00892	585394.RHOM_00055	1.39e-68	209.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia	186801|Clostridia	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
ALEKFNDC_00893	622312.ROSEINA2194_03241	2.84e-126	373.0	COG0840@1|root,COG4905@1|root,COG0840@2|Bacteria,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
ALEKFNDC_00894	622312.ROSEINA2194_03242	3.22e-169	476.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, alpha	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
ALEKFNDC_00895	622312.ROSEINA2194_03243	3.18e-119	342.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia	186801|Clostridia	C	Fe-S type, tartrate fumarate subfamily, beta	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
ALEKFNDC_00897	585394.RHOM_00105	9.32e-179	505.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
ALEKFNDC_00898	221027.JO40_09765	3.38e-75	233.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
ALEKFNDC_00899	585394.RHOM_00765	7.44e-53	169.0	2C12Y@1|root,32STC@2|Bacteria,1VCPE@1239|Firmicutes,24Q1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00900	397287.C807_02308	4.27e-103	305.0	COG1083@1|root,COG1083@2|Bacteria,1UY6H@1239|Firmicutes,25DGH@186801|Clostridia,27U9P@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_3
ALEKFNDC_00901	622312.ROSEINA2194_00398	1.33e-177	505.0	COG4641@1|root,COG4641@2|Bacteria,1V3QP@1239|Firmicutes,24I06@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3880,Glyco_trans_1_2
ALEKFNDC_00902	1235802.C823_01266	3.4e-161	471.0	COG1887@1|root,COG1887@2|Bacteria,1UGR4@1239|Firmicutes,24F3S@186801|Clostridia,25YIM@186806|Eubacteriaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
ALEKFNDC_00903	1121007.AUML01000046_gene4057	1.07e-05	53.5	COG0500@1|root,COG2226@2|Bacteria,4NXY3@976|Bacteroidetes,1I6ZS@117743|Flavobacteriia,2YGZP@290174|Aquimarina	976|Bacteroidetes	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_31
ALEKFNDC_00904	180332.JTGN01000011_gene627	7.33e-79	236.0	COG1898@1|root,COG1898@2|Bacteria,1V3X4@1239|Firmicutes,24ITM@186801|Clostridia	186801|Clostridia	M	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
ALEKFNDC_00905	536227.CcarbDRAFT_1567	6.49e-169	482.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,36DUG@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ALEKFNDC_00906	97139.C824_03260	6.47e-45	166.0	COG1215@1|root,COG1215@2|Bacteria,1UIBS@1239|Firmicutes,25EGT@186801|Clostridia,36UQ5@31979|Clostridiaceae	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_00907	613026.HRAG_00921	1.62e-64	208.0	COG2227@1|root,COG2227@2|Bacteria,1PC2A@1224|Proteobacteria,432EZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
ALEKFNDC_00908	1002367.HMPREF0673_00327	1.32e-64	213.0	2DPVG@1|root,333JE@2|Bacteria,4NT9X@976|Bacteroidetes,2FZ2I@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00909	1235802.C823_01275	9.92e-116	338.0	COG0500@1|root,COG0500@2|Bacteria,1UP91@1239|Firmicutes,25H94@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00910	1235802.C823_01269	1.01e-109	325.0	COG1213@1|root,COG1213@2|Bacteria,1V42C@1239|Firmicutes,24HN4@186801|Clostridia	186801|Clostridia	M	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
ALEKFNDC_00911	1235802.C823_01273	1.3e-131	385.0	COG3146@1|root,COG3146@2|Bacteria,1V9A5@1239|Firmicutes,24EID@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6,FemAB
ALEKFNDC_00913	585394.RHOM_00795	1.21e-142	419.0	COG1216@1|root,COG1216@2|Bacteria,1V5UZ@1239|Firmicutes,24J2K@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_5
ALEKFNDC_00914	585394.RHOM_00785	5.67e-217	602.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia	186801|Clostridia	M	synthase	pseI	-	2.5.1.56,2.5.1.97	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	-	R01804,R04435,R09841	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
ALEKFNDC_00915	585394.RHOM_00790	3.7e-114	342.0	COG3980@1|root,COG3980@2|Bacteria,1U2ZW@1239|Firmicutes,24HWM@186801|Clostridia	186801|Clostridia	M	pseudaminic acid biosynthesis-associated protein PseG	pseG	-	3.6.1.57	ko:K15897	ko00520,map00520	-	R09834	RC00005,RC00078	ko00000,ko00001,ko01000	-	-	-	Glyco_tran_28_C
ALEKFNDC_00916	585394.RHOM_00800	3.54e-240	663.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	pseC	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
ALEKFNDC_00917	585394.RHOM_00820	7.8e-151	429.0	COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia	186801|Clostridia	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	-	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
ALEKFNDC_00918	1235790.C805_03273	4.53e-170	501.0	29YSV@1|root,33YJU@2|Bacteria,1UJXA@1239|Firmicutes,250SW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_00919	1235790.C805_03269	1.15e-250	703.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,247MU@186801|Clostridia,25VFY@186806|Eubacteriaceae	186801|Clostridia	E	HMGL-like	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
ALEKFNDC_00920	398767.Glov_0788	1.72e-83	254.0	COG1028@1|root,COG1028@2|Bacteria,1RD0G@1224|Proteobacteria	1224|Proteobacteria	IQ	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
ALEKFNDC_00921	906968.Trebr_0813	4.83e-126	372.0	COG0337@1|root,COG0337@2|Bacteria,2J69J@203691|Spirochaetes	203691|Spirochaetes	H	3-dehydroquinate synthase	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
ALEKFNDC_00922	622312.ROSEINA2194_02551	0.0	886.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,248Z9@186801|Clostridia	186801|Clostridia	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ALEKFNDC_00923	397290.C810_00227	1.13e-123	363.0	COG0451@1|root,COG0451@2|Bacteria,1UZR1@1239|Firmicutes,24DWP@186801|Clostridia,27KXP@186928|unclassified Lachnospiraceae	186801|Clostridia	GM	GDP-mannose 4,6 dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
ALEKFNDC_00924	1235790.C805_03253	4.43e-135	388.0	COG1208@1|root,COG1208@2|Bacteria,1V316@1239|Firmicutes,24GJU@186801|Clostridia,25YFN@186806|Eubacteriaceae	186801|Clostridia	JM	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00925	1235790.C805_03251	1.25e-192	541.0	COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia,25VIS@186806|Eubacteriaceae	186801|Clostridia	GM	RmlD substrate binding domain	rfbG	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ALEKFNDC_00926	1235790.C805_03250	1.03e-164	462.0	COG1208@1|root,COG1208@2|Bacteria,1TPII@1239|Firmicutes,249GT@186801|Clostridia,25VFZ@186806|Eubacteriaceae	186801|Clostridia	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
ALEKFNDC_00927	1235790.C805_03249	1.31e-277	764.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25VRM@186806|Eubacteriaceae	186801|Clostridia	M	DegT/DnrJ/EryC1/StrS aminotransferase family	rfbH	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
ALEKFNDC_00930	622312.ROSEINA2194_00406	2.07e-170	484.0	COG1215@1|root,COG1215@2|Bacteria,1UMA5@1239|Firmicutes,25GD8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_00931	622312.ROSEINA2194_00426	7.36e-317	874.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_00932	585394.RHOM_00900	2.48e-166	478.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1TSF5@1239|Firmicutes,25B5G@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2,TPR_2,TPR_7,TPR_8
ALEKFNDC_00933	622312.ROSEINA2194_00427	1.22e-279	776.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_00934	585394.RHOM_00920	9.44e-218	610.0	COG4641@1|root,COG4641@2|Bacteria,1V0EG@1239|Firmicutes,24DZB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ALEKFNDC_00935	585394.RHOM_00925	2.09e-244	676.0	COG4641@1|root,COG4641@2|Bacteria,1TR7G@1239|Firmicutes,24ATN@186801|Clostridia	186801|Clostridia	S	DUF based on E. rectale Gene description (DUF3880)	-	-	-	ko:K06320	-	-	-	-	ko00000	-	-	-	DUF3880,Glyco_trans_1_2
ALEKFNDC_00936	585394.RHOM_00930	7.29e-161	468.0	COG1345@1|root,COG1345@2|Bacteria,1U3CE@1239|Firmicutes,24B6P@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliD_C,FliD_N
ALEKFNDC_00937	140626.JHWB01000009_gene1219	2.28e-27	100.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia	186801|Clostridia	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
ALEKFNDC_00938	585394.RHOM_00945	3.44e-117	335.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
ALEKFNDC_00939	585394.RHOM_06065	5.26e-112	336.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
ALEKFNDC_00940	585394.RHOM_06070	9.36e-294	802.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia	186801|Clostridia	G	Belongs to the rhamnose isomerase family	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
ALEKFNDC_00941	585394.RHOM_06075	4.33e-195	541.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ALEKFNDC_00942	471875.RUMLAC_00658	4.05e-59	187.0	COG1846@1|root,COG1846@2|Bacteria,1V9N7@1239|Firmicutes,24NET@186801|Clostridia,3WKTM@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ALEKFNDC_00943	471875.RUMLAC_00657	6.02e-211	595.0	COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia,3WJRF@541000|Ruminococcaceae	186801|Clostridia	F	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	Cytidylate_kin2
ALEKFNDC_00944	1235792.C808_04472	1.5e-237	672.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27J3F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_00945	622312.ROSEINA2194_00851	0.0	1585.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_00946	622312.ROSEINA2194_00853	3.33e-128	365.0	28NMC@1|root,2ZA4G@2|Bacteria,1UYCN@1239|Firmicutes,24ACB@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
ALEKFNDC_00947	471875.RUMLAC_02592	2.05e-78	240.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3WJRA@541000|Ruminococcaceae	186801|Clostridia	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_00948	411463.EUBVEN_02439	0.0	879.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,25VCK@186806|Eubacteriaceae	186801|Clostridia	P	ABC transporter, ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00949	471875.RUMLAC_02590	0.0	916.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3WHFU@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_00950	622312.ROSEINA2194_03392	3.08e-57	184.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00951	478749.BRYFOR_07844	2.21e-75	241.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
ALEKFNDC_00952	585394.RHOM_14785	2.59e-99	290.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
ALEKFNDC_00953	585394.RHOM_03850	1.74e-49	165.0	2E0ER@1|root,32W16@2|Bacteria,1VDMK@1239|Firmicutes,24T4F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
ALEKFNDC_00954	585394.RHOM_03855	1.56e-256	703.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia	186801|Clostridia	E	Branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
ALEKFNDC_00955	622312.ROSEINA2194_02267	1.53e-282	781.0	COG2317@1|root,COG2317@2|Bacteria,1TPS6@1239|Firmicutes,249NK@186801|Clostridia	186801|Clostridia	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
ALEKFNDC_00956	622312.ROSEINA2194_02268	2.33e-104	306.0	COG0546@1|root,COG0546@2|Bacteria,1V4W6@1239|Firmicutes,24DB6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ALEKFNDC_00957	585394.RHOM_04250	1.37e-174	493.0	COG0618@1|root,COG0618@2|Bacteria,1UKBY@1239|Firmicutes,24EAR@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
ALEKFNDC_00958	622312.ROSEINA2194_02271	0.0	1928.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
ALEKFNDC_00959	1256908.HMPREF0373_00101	0.0	1419.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,25VB4@186806|Eubacteriaceae	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
ALEKFNDC_00960	1235793.C809_01831	7.87e-34	119.0	COG4818@1|root,COG4818@2|Bacteria,1UN6A@1239|Firmicutes,25GXJ@186801|Clostridia,27Q73@186928|unclassified Lachnospiraceae	186801|Clostridia	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00961	585394.RHOM_11175	1.71e-148	420.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia	186801|Clostridia	KT	response regulator receiver	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_00962	585394.RHOM_11170	2.06e-206	609.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ALEKFNDC_00963	622312.ROSEINA2194_02996	5.95e-166	469.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia	186801|Clostridia	J	S1 RNA binding domain protein	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
ALEKFNDC_00964	585394.RHOM_05400	7.13e-83	247.0	COG1846@1|root,COG1846@2|Bacteria,1V1U2@1239|Firmicutes,24FR9@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
ALEKFNDC_00965	585394.RHOM_05405	5.76e-64	210.0	COG0741@1|root,COG0741@2|Bacteria,1V6DD@1239|Firmicutes,24JDA@186801|Clostridia	186801|Clostridia	M	transglycosylase	yjbJ	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT
ALEKFNDC_00966	585394.RHOM_05410	2.35e-136	390.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid permease (azaleucine resistance)	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
ALEKFNDC_00967	585394.RHOM_05415	2.56e-53	169.0	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia	186801|Clostridia	E	branched-chain amino acid	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
ALEKFNDC_00968	585394.RHOM_05420	9.01e-313	851.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia	186801|Clostridia	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
ALEKFNDC_00969	585394.RHOM_05425	1.61e-139	398.0	28XBK@1|root,2ZJ9G@2|Bacteria,1V203@1239|Firmicutes,24E0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00970	585394.RHOM_05010	2.38e-45	148.0	2EK04@1|root,33DQP@2|Bacteria,1VM4D@1239|Firmicutes,24WYN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00971	585394.RHOM_11760	5.86e-149	437.0	COG0544@1|root,COG0544@2|Bacteria,1V3TB@1239|Firmicutes,24I3U@186801|Clostridia	186801|Clostridia	O	Bacterial trigger factor protein (TF) C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Trigger_C
ALEKFNDC_00972	585394.RHOM_11475	8.4e-151	434.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_00973	397291.C804_03204	0.0	1089.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,27I65@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
ALEKFNDC_00974	585394.RHOM_11485	0.0	1046.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia	186801|Clostridia	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ALEKFNDC_00975	397291.C804_03676	1.37e-160	457.0	COG2730@1|root,COG2730@2|Bacteria,1TT32@1239|Firmicutes,24DD1@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00976	573061.Clocel_3339	2.59e-98	298.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,25BJI@186801|Clostridia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding
ALEKFNDC_00977	622312.ROSEINA2194_02877	1.33e-85	271.0	COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes,24F20@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ALEKFNDC_00978	585394.RHOM_11490	1.58e-160	465.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia	186801|Clostridia	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
ALEKFNDC_00980	585394.RHOM_03980	5.95e-41	147.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
ALEKFNDC_00981	622312.ROSEINA2194_02883	1.14e-59	185.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
ALEKFNDC_00982	585394.RHOM_03965	0.0	952.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
ALEKFNDC_00983	585394.RHOM_03960	8.88e-128	379.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia	186801|Clostridia	S	Secreted protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
ALEKFNDC_00984	585394.RHOM_03955	2.59e-180	507.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
ALEKFNDC_00986	622312.ROSEINA2194_03374	2.14e-316	874.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia	186801|Clostridia	L	Single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ALEKFNDC_00987	622312.ROSEINA2194_03375	1.69e-113	332.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
ALEKFNDC_00988	585394.RHOM_03935	2.26e-248	689.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia	186801|Clostridia	M	Peptidoglycan binding domain protein	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
ALEKFNDC_00989	622312.ROSEINA2194_03378	0.0	991.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
ALEKFNDC_00990	622312.ROSEINA2194_00443	4.45e-56	184.0	2DSNT@1|root,33GUR@2|Bacteria,1VNR5@1239|Firmicutes,24WQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00991	622312.ROSEINA2194_01974	2.6e-169	483.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
ALEKFNDC_00992	585394.RHOM_03910	1.21e-82	260.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia	186801|Clostridia	G	COG1879 ABC-type sugar transport system periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
ALEKFNDC_00993	622312.ROSEINA2194_01972	0.0	932.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
ALEKFNDC_00994	622312.ROSEINA2194_01971	1.22e-275	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
ALEKFNDC_00995	585394.RHOM_03895	2.7e-38	130.0	2FJ6E@1|root,34AWI@2|Bacteria,1W149@1239|Firmicutes,254EU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_00996	585394.RHOM_03890	3.55e-213	591.0	COG4211@1|root,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	mglC	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
ALEKFNDC_00997	622312.ROSEINA2194_01968	0.0	909.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
ALEKFNDC_00998	585394.RHOM_03880	2e-202	568.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4,TAT_signal
ALEKFNDC_00999	585394.RHOM_03875	2.21e-65	201.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
ALEKFNDC_01000	585394.RHOM_04225	1.45e-297	813.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia	186801|Clostridia	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
ALEKFNDC_01001	585394.RHOM_04220	9.79e-119	342.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
ALEKFNDC_01002	585394.RHOM_04215	8.21e-225	622.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia	186801|Clostridia	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
ALEKFNDC_01003	585394.RHOM_04210	1.71e-105	305.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
ALEKFNDC_01004	585394.RHOM_04205	0.0	984.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
ALEKFNDC_01005	585394.RHOM_04200	3.65e-114	330.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
ALEKFNDC_01006	622312.ROSEINA2194_02252	1.03e-38	132.0	2ETB0@1|root,33KUX@2|Bacteria,1VPRN@1239|Firmicutes,24WSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01007	585394.RHOM_07690	1.4e-91	271.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
ALEKFNDC_01008	585394.RHOM_07695	1.5e-146	419.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
ALEKFNDC_01009	585394.RHOM_07700	4.99e-213	592.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia	186801|Clostridia	D	Cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
ALEKFNDC_01010	585394.RHOM_07705	2.19e-91	275.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia	186801|Clostridia	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
ALEKFNDC_01012	585394.RHOM_07710	7.2e-283	776.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia	186801|Clostridia	P	aluminum resistance protein	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
ALEKFNDC_01013	622312.ROSEINA2194_03770	4.58e-178	501.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
ALEKFNDC_01014	622312.ROSEINA2194_03771	0.0	907.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
ALEKFNDC_01015	1235802.C823_03200	1.45e-100	298.0	COG1351@1|root,COG1351@2|Bacteria,1TRAA@1239|Firmicutes,249DJ@186801|Clostridia,25V4I@186806|Eubacteriaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
ALEKFNDC_01016	585394.RHOM_07725	0.0	1498.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
ALEKFNDC_01017	585394.RHOM_07730	2.31e-251	705.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia	186801|Clostridia	H	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
ALEKFNDC_01018	622312.ROSEINA2194_03775	6.64e-175	502.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ALEKFNDC_01019	397288.C806_02312	2.5e-10	61.6	2EJV3@1|root,33DJR@2|Bacteria,1VKNR@1239|Firmicutes,24UH1@186801|Clostridia,27TPQ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01020	585394.RHOM_07745	9.6e-261	730.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
ALEKFNDC_01021	622312.ROSEINA2194_03780	1.08e-87	260.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia	186801|Clostridia	F	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
ALEKFNDC_01022	585394.RHOM_07755	8.91e-110	334.0	COG1480@1|root,COG1480@2|Bacteria	2|Bacteria	O	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	-
ALEKFNDC_01023	585394.RHOM_07760	1.73e-207	578.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia	186801|Clostridia	T	phosphate starvation-inducible protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
ALEKFNDC_01024	585394.RHOM_07765	1e-161	468.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia	186801|Clostridia	S	Sporulation protein YqfD	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
ALEKFNDC_01025	1235790.C805_01829	1.94e-29	107.0	2B2ZJ@1|root,31VKQ@2|Bacteria,1TVEP@1239|Firmicutes,25NEX@186801|Clostridia,25XCH@186806|Eubacteriaceae	186801|Clostridia	S	YabP family	-	-	-	-	-	-	-	-	-	-	-	-	YabP
ALEKFNDC_01026	585394.RHOM_07775	6.08e-233	650.0	COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,24848@186801|Clostridia	186801|Clostridia	F	pyrimidine-nucleoside phosphorylase	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08925	Glycos_trans_3N,Glycos_transf_3,PYNP_C
ALEKFNDC_01027	411490.ANACAC_03749	1.22e-22	96.3	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24NSX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
ALEKFNDC_01028	622312.ROSEINA2194_03787	0.0	1269.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
ALEKFNDC_01029	622312.ROSEINA2194_03788	7.67e-87	257.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia	186801|Clostridia	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
ALEKFNDC_01030	622312.ROSEINA2194_03789	4.99e-117	343.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia	186801|Clostridia	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
ALEKFNDC_01031	33035.JPJF01000004_gene1973	4.25e-53	180.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia	186801|Clostridia	V	PFAM SCP-like extracellular	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
ALEKFNDC_01032	553973.CLOHYLEM_07594	1.22e-134	383.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,21Y4Q@1506553|Lachnoclostridium	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
ALEKFNDC_01033	742765.HMPREF9457_00537	2.87e-194	550.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,27WJP@189330|Dorea	186801|Clostridia	P	Voltage gated chloride channel	eriC	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
ALEKFNDC_01034	1256908.HMPREF0373_02751	1.9e-289	799.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,25V4N@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21.2	-	-	SSF
ALEKFNDC_01035	1395587.P364_0126160	6.38e-190	546.0	COG3507@1|root,COG3507@2|Bacteria,1UY12@1239|Firmicutes,4HEUT@91061|Bacilli,27497@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
ALEKFNDC_01036	585394.RHOM_07785	3.32e-81	244.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
ALEKFNDC_01038	622312.ROSEINA2194_03792	1.06e-103	303.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
ALEKFNDC_01039	622312.ROSEINA2194_03801	7.8e-95	295.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
ALEKFNDC_01040	585394.RHOM_07810	0.0	1000.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
ALEKFNDC_01041	622312.ROSEINA2194_03804	4.34e-307	866.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia	186801|Clostridia	D	FtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
ALEKFNDC_01042	585394.RHOM_00620	1.11e-302	840.0	COG1256@1|root,COG1256@2|Bacteria,1TPXH@1239|Firmicutes,249PE@186801|Clostridia	186801|Clostridia	N	TIGRFAM Flagellar hook-associated protein, FlgK	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
ALEKFNDC_01043	585394.RHOM_00615	1.59e-58	187.0	2APQ2@1|root,31ETS@2|Bacteria,1V6HK@1239|Firmicutes,24KPZ@186801|Clostridia	186801|Clostridia	S	FlgN protein	-	-	-	-	-	-	-	-	-	-	-	-	FlgN
ALEKFNDC_01044	622312.ROSEINA2194_00835	1.74e-30	110.0	COG2747@1|root,COG2747@2|Bacteria,1VFH9@1239|Firmicutes,24QZ8@186801|Clostridia	186801|Clostridia	KNU	Anti-sigma-28 factor, FlgM	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
ALEKFNDC_01045	1121115.AXVN01000103_gene864	8.28e-101	297.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ALEKFNDC_01046	642492.Clole_0471	3.96e-244	698.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
ALEKFNDC_01047	1235793.C809_01339	1.41e-37	129.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,24JAB@186801|Clostridia,27NWQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
ALEKFNDC_01048	585394.RHOM_02250	5.31e-119	345.0	COG2364@1|root,COG2364@2|Bacteria,1US08@1239|Firmicutes,24DPK@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01049	411474.COPEUT_02079	3.17e-115	340.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_01050	622312.ROSEINA2194_00274	6.42e-179	504.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
ALEKFNDC_01051	483218.BACPEC_03086	7.68e-62	194.0	2BIDU@1|root,32CK4@2|Bacteria,1VDRI@1239|Firmicutes,24NJ9@186801|Clostridia,26BYT@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01052	469617.FUAG_02364	7.24e-142	420.0	COG0534@1|root,COG0534@2|Bacteria,37936@32066|Fusobacteria	32066|Fusobacteria	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_01053	411489.CLOL250_02328	1.99e-76	234.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,36I0R@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
ALEKFNDC_01054	411489.CLOL250_02329	2.77e-170	481.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,36DZ4@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
ALEKFNDC_01055	585394.RHOM_14920	2.09e-227	629.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia	186801|Clostridia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ALEKFNDC_01056	585394.RHOM_14935	0.0	972.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
ALEKFNDC_01057	1280664.AUIX01000021_gene2964	3.78e-170	487.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,4BX6M@830|Butyrivibrio	186801|Clostridia	G	Amidohydrolase family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ALEKFNDC_01058	140626.JHWB01000009_gene1454	5.56e-116	338.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
ALEKFNDC_01059	1121871.AUAT01000005_gene1736	3.68e-16	86.3	COG2971@1|root,COG2971@2|Bacteria,1V47Z@1239|Firmicutes,4IR14@91061|Bacilli	91061|Bacilli	G	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
ALEKFNDC_01060	457421.CBFG_01718	0.0	1025.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ALEKFNDC_01061	478749.BRYFOR_06209	1.37e-255	709.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
ALEKFNDC_01062	478749.BRYFOR_06207	1.32e-104	310.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
ALEKFNDC_01063	592026.GCWU0000282_002961	0.0	1340.0	COG1112@1|root,COG1112@2|Bacteria,1TP20@1239|Firmicutes,24BMH@186801|Clostridia	186801|Clostridia	L	COG1112 Superfamily I DNA and RNA	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12,DUF2726
ALEKFNDC_01064	1256908.HMPREF0373_02029	3.13e-184	522.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,25VKN@186806|Eubacteriaceae	186801|Clostridia	HP	K02013 iron complex transport system ATP-binding protein	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
ALEKFNDC_01065	1256908.HMPREF0373_02030	2.76e-178	503.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,25VB9@186806|Eubacteriaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
ALEKFNDC_01066	1256908.HMPREF0373_02031	2.66e-256	717.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,25UTP@186806|Eubacteriaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
ALEKFNDC_01067	585394.RHOM_08995	1.17e-284	790.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia	186801|Clostridia	H	cobalt chelatase	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
ALEKFNDC_01069	1235793.C809_02698	1.71e-34	132.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27JG4@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Cache_2	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2,sCache_3_3
ALEKFNDC_01070	585394.RHOM_14165	4.38e-108	340.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2,sCache_3_3
ALEKFNDC_01071	515620.EUBELI_20098	6.73e-189	536.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia,25WUW@186806|Eubacteriaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
ALEKFNDC_01072	633147.Olsu_0367	0.000883	42.4	COG0583@1|root,COG0583@2|Bacteria,2HF43@201174|Actinobacteria,4CUXJ@84998|Coriobacteriia	84998|Coriobacteriia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_01073	1458462.JNLK01000001_gene4	5.23e-80	244.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,27MEA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
ALEKFNDC_01074	622312.ROSEINA2194_00442	6.57e-282	775.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia	186801|Clostridia	S	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
ALEKFNDC_01075	411461.DORFOR_02133	2e-279	770.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,27WEJ@189330|Dorea	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
ALEKFNDC_01077	585394.RHOM_12400	1.03e-125	378.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
ALEKFNDC_01078	622312.ROSEINA2194_02611	4.67e-297	813.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
ALEKFNDC_01079	585394.RHOM_12390	6.68e-52	164.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ALEKFNDC_01080	585394.RHOM_12385	8.33e-179	501.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
ALEKFNDC_01081	585394.RHOM_12380	4.8e-143	430.0	2AJ90@1|root,319TX@2|Bacteria,1VFA5@1239|Firmicutes,25DCM@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
ALEKFNDC_01082	585394.RHOM_12375	5.63e-253	694.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
ALEKFNDC_01083	585394.RHOM_12370	5.25e-201	557.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia	186801|Clostridia	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
ALEKFNDC_01084	585394.RHOM_12365	5.1e-125	357.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
ALEKFNDC_01085	585394.RHOM_12360	3.2e-137	395.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
ALEKFNDC_01086	585394.RHOM_12355	6.56e-264	728.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
ALEKFNDC_01087	1235790.C805_00459	3.07e-103	338.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,25Y5N@186806|Eubacteriaceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
ALEKFNDC_01088	585394.RHOM_12340	8.8e-282	777.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia	186801|Clostridia	M	sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
ALEKFNDC_01089	585394.RHOM_12335	5.53e-108	332.0	COG0489@1|root,COG3944@1|root,COG0489@2|Bacteria,COG3944@2|Bacteria	2|Bacteria	M	capsule polysaccharide biosynthetic process	wzc	-	2.7.10.1,2.7.10.2	ko:K08252,ko:K08253,ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
ALEKFNDC_01090	585394.RHOM_12330	6.43e-121	360.0	2A542@1|root,30TSQ@2|Bacteria,1V4Q2@1239|Firmicutes,24ISW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01093	585394.RHOM_12310	9.01e-226	629.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
ALEKFNDC_01094	585394.RHOM_12305	7.75e-198	556.0	COG0438@1|root,COG0438@2|Bacteria,1UI11@1239|Firmicutes,24CV8@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
ALEKFNDC_01095	585394.RHOM_12300	1.03e-207	582.0	COG0438@1|root,COG0438@2|Bacteria,1VE1G@1239|Firmicutes	1239|Firmicutes	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
ALEKFNDC_01096	585394.RHOM_12295	6.17e-170	480.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia	186801|Clostridia	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
ALEKFNDC_01097	585394.RHOM_12290	1.72e-152	436.0	COG1216@1|root,COG1216@2|Bacteria,1UD0A@1239|Firmicutes,24GXB@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	GNT-I,Glycos_transf_2
ALEKFNDC_01098	585394.RHOM_12285	1.58e-150	428.0	COG1216@1|root,COG1216@2|Bacteria,1VBWR@1239|Firmicutes,24NB1@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_01099	585394.RHOM_12280	1.63e-132	385.0	COG1216@1|root,COG1216@2|Bacteria,1VAHM@1239|Firmicutes,24MBF@186801|Clostridia	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_01100	552531.BIF_02151	3.47e-137	410.0	COG2244@1|root,COG2244@2|Bacteria,2IA1K@201174|Actinobacteria,4D0KU@85004|Bifidobacteriales	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
ALEKFNDC_01101	1235800.C819_00199	2.64e-95	293.0	COG0438@1|root,COG0438@2|Bacteria,1V76V@1239|Firmicutes,25IUU@186801|Clostridia,27NJE@186928|unclassified Lachnospiraceae	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01103	397290.C810_03895	1.78e-28	132.0	COG4193@1|root,COG5492@1|root,COG4193@2|Bacteria,COG5492@2|Bacteria,1TRTM@1239|Firmicutes,24C4N@186801|Clostridia,27K3Z@186928|unclassified Lachnospiraceae	186801|Clostridia	G	SH3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cadherin-like,Dockerin_1,Glucosaminidase,SH3_3
ALEKFNDC_01104	397290.C810_03819	7.98e-254	704.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,27K11@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
ALEKFNDC_01105	397290.C810_03894	2.85e-183	581.0	COG0860@1|root,COG4733@1|root,COG0860@2|Bacteria,COG4733@2|Bacteria,1UZ49@1239|Firmicutes,25F7R@186801|Clostridia,27JMX@186928|unclassified Lachnospiraceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,Big_2,GBS_Bsp-like,Glucosaminidase,RicinB_lectin_2,fn3
ALEKFNDC_01106	411483.FAEPRAA2165_00991	4.57e-87	267.0	COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,24EMU@186801|Clostridia,3WH23@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_01107	622312.ROSEINA2194_01132	4.71e-33	127.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
ALEKFNDC_01108	585394.RHOM_04985	2.11e-224	625.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
ALEKFNDC_01109	622312.ROSEINA2194_00338	7.26e-135	390.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
ALEKFNDC_01110	622312.ROSEINA2194_00337	6.75e-76	228.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,24QK7@186801|Clostridia	186801|Clostridia	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
ALEKFNDC_01111	585394.RHOM_05320	3.69e-175	497.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ALEKFNDC_01112	585394.RHOM_05325	5.11e-200	577.0	COG2199@1|root,COG2984@1|root,COG2199@2|Bacteria,COG2984@2|Bacteria,1TS5J@1239|Firmicutes,25E4Y@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,GGDEF,PAS_3,PAS_9
ALEKFNDC_01113	585394.RHOM_05330	0.0	1159.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia	186801|Clostridia	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
ALEKFNDC_01114	622312.ROSEINA2194_00317	4.16e-137	389.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia	186801|Clostridia	L	PFAM single-strand binding protein Primosomal replication protein n	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
ALEKFNDC_01115	585394.RHOM_05340	8.91e-179	501.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
ALEKFNDC_01116	585394.RHOM_05350	5.25e-149	423.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
ALEKFNDC_01117	585394.RHOM_05355	0.0	1160.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
ALEKFNDC_01118	585394.RHOM_05365	1.4e-160	454.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
ALEKFNDC_01119	585394.RHOM_05370	0.0	872.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
ALEKFNDC_01120	585394.RHOM_05375	1.38e-191	533.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
ALEKFNDC_01121	585394.RHOM_05380	7.48e-222	617.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ALEKFNDC_01122	585394.RHOM_05380	3.67e-26	104.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
ALEKFNDC_01123	585394.RHOM_05385	1.57e-213	597.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
ALEKFNDC_01124	585394.RHOM_05390	9.64e-179	510.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia	186801|Clostridia	E	agmatine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
ALEKFNDC_01125	585394.RHOM_05395	6.32e-178	499.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
ALEKFNDC_01126	585394.RHOM_11155	2.89e-227	627.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
ALEKFNDC_01127	397291.C804_00556	5.38e-06	48.5	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
ALEKFNDC_01128	397290.C810_01607	7.99e-214	617.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27IZ3@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
ALEKFNDC_01129	585394.RHOM_11145	1.01e-145	420.0	COG1879@1|root,COG1879@2|Bacteria,1UYPR@1239|Firmicutes,248AW@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K17213	ko02010,map02010	M00593	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
ALEKFNDC_01130	397291.C804_05620	1.36e-76	233.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,27MP7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ALEKFNDC_01131	622312.ROSEINA2194_01780	3.21e-43	145.0	2C9RU@1|root,349H4@2|Bacteria,1VYXI@1239|Firmicutes,253A6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01132	411468.CLOSCI_00849	1.51e-22	88.6	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,223NI@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
ALEKFNDC_01134	180332.JTGN01000002_gene5663	1.16e-50	207.0	COG2755@1|root,COG4409@1|root,COG5492@1|root,COG2755@2|Bacteria,COG4409@2|Bacteria,COG5492@2|Bacteria,1TQRX@1239|Firmicutes,247TP@186801|Clostridia	186801|Clostridia	G	Psort location Cellwall, score	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,FIVAR,Laminin_G_3,Lipase_GDSL_2,Sialidase
ALEKFNDC_01135	585394.RHOM_15945	1.61e-105	313.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01136	411462.DORLON_02271	7.05e-10	60.5	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,27W4K@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01137	622312.ROSEINA2194_03605	2.08e-113	328.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_01138	97139.C824_00759	3.74e-245	683.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,24CXI@186801|Clostridia,36J6B@31979|Clostridiaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
ALEKFNDC_01139	742740.HMPREF9474_04328	1.04e-30	115.0	COG1396@1|root,COG1396@2|Bacteria,1VT6H@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_01146	1385510.N781_04650	8.22e-77	241.0	COG0834@1|root,COG0834@2|Bacteria,1TR13@1239|Firmicutes,4HBRP@91061|Bacilli,2YA3J@289201|Pontibacillus	91061|Bacilli	ET	Belongs to the bacterial solute-binding protein 3 family	tcyA	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
ALEKFNDC_01147	1410633.JHWR01000001_gene1255	3.56e-126	394.0	COG2200@1|root,COG2200@2|Bacteria,1V15N@1239|Firmicutes,24C2G@186801|Clostridia,27K15@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
ALEKFNDC_01148	585394.RHOM_06170	0.0	1028.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia	186801|Clostridia	G	arabinogalactan	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Big_4,Glyco_hydro_53
ALEKFNDC_01149	585394.RHOM_08575	5.73e-185	549.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
ALEKFNDC_01150	658086.HMPREF0994_03302	9.48e-54	172.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
ALEKFNDC_01153	515620.EUBELI_20437	9.82e-135	421.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,25ZJN@186806|Eubacteriaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
ALEKFNDC_01154	1304866.K413DRAFT_4331	3.96e-113	366.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36DH1@31979|Clostridiaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1
ALEKFNDC_01155	397291.C804_02931	1.45e-105	318.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,27UBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	ROK family	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI,ROK
ALEKFNDC_01156	397288.C806_01642	3.57e-115	346.0	COG1609@1|root,COG1609@2|Bacteria,1TT82@1239|Firmicutes,24G8D@186801|Clostridia,27QNK@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_1
ALEKFNDC_01157	397288.C806_01638	3.53e-191	544.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,248YF@186801|Clostridia,27JVW@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:DUF1237	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
ALEKFNDC_01158	702450.CUW_2164	0.0	1151.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,3VPJS@526524|Erysipelotrichia	526524|Erysipelotrichia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
ALEKFNDC_01159	397291.C804_02930	0.0	1297.0	COG3291@1|root,COG4724@1|root,COG3291@2|Bacteria,COG4724@2|Bacteria,1TPGB@1239|Firmicutes,24AII@186801|Clostridia	186801|Clostridia	G	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_85,PKD
ALEKFNDC_01160	1280673.AUJJ01000001_gene2237	3.66e-139	405.0	COG1609@1|root,COG1609@2|Bacteria,1TRG8@1239|Firmicutes,249CT@186801|Clostridia,4BZ5Y@830|Butyrivibrio	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_01161	1280676.AUJO01000002_gene1480	6.37e-194	541.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,4BX4G@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_01162	1280676.AUJO01000002_gene1479	1.79e-175	494.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,4C1Y7@830|Butyrivibrio	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_01163	1280676.AUJO01000002_gene1478	5.44e-257	716.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,4BYV9@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
ALEKFNDC_01164	397291.C804_02928	2.22e-217	602.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_01165	457412.RSAG_02071	0.0	936.0	COG1874@1|root,COG1874@2|Bacteria,1UZRC@1239|Firmicutes,24EDS@186801|Clostridia	186801|Clostridia	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01166	658086.HMPREF0994_01029	5.86e-246	709.0	28I74@1|root,2Z8A0@2|Bacteria,1VR23@1239|Firmicutes	1239|Firmicutes	S	COG NOG26804 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01167	397291.C804_02929	0.0	1608.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,27KWU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
ALEKFNDC_01168	1128421.JAGA01000003_gene2954	5.02e-31	131.0	COG2211@1|root,COG2211@2|Bacteria,2NR8E@2323|unclassified Bacteria	2|Bacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ALEKFNDC_01169	585394.RHOM_06565	2.18e-137	394.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
ALEKFNDC_01170	585394.RHOM_06570	5.29e-177	500.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
ALEKFNDC_01171	622312.ROSEINA2194_01198	2.12e-207	578.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia	186801|Clostridia	E	Beta-eliminating lyase	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
ALEKFNDC_01172	585394.RHOM_06580	1.83e-218	605.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia	186801|Clostridia	EJ	L-asparaginase	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
ALEKFNDC_01173	585394.RHOM_06585	1.92e-79	242.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
ALEKFNDC_01175	622312.ROSEINA2194_01760	1.03e-257	711.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia	186801|Clostridia	P	Chloride transporter, ClC family	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
ALEKFNDC_01176	622312.ROSEINA2194_01762	8.92e-279	770.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	amyE	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
ALEKFNDC_01177	622312.ROSEINA2194_01763	7.84e-184	513.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_01178	585394.RHOM_06625	3.01e-178	499.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_01179	585394.RHOM_06630	5.88e-193	541.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_01180	622312.ROSEINA2194_01766	2.18e-314	862.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia	186801|Clostridia	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
ALEKFNDC_01181	585394.RHOM_06640	2.17e-135	394.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
ALEKFNDC_01182	585394.RHOM_06645	1.17e-267	744.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
ALEKFNDC_01183	585394.RHOM_06665	1.79e-101	300.0	COG2364@1|root,COG2364@2|Bacteria,1V7N6@1239|Firmicutes,25CWQ@186801|Clostridia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01184	585394.RHOM_06660	4.36e-59	191.0	2DY6R@1|root,32V4T@2|Bacteria,1VDMI@1239|Firmicutes,24D1Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01185	585394.RHOM_06670	5.9e-172	483.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
ALEKFNDC_01186	585394.RHOM_06675	1.68e-293	803.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ALEKFNDC_01187	622312.ROSEINA2194_03293	8.31e-141	402.0	COG2220@1|root,COG2220@2|Bacteria,1V3HY@1239|Firmicutes,24HK9@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	folD4	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
ALEKFNDC_01189	585394.RHOM_06690	0.0	1543.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ALEKFNDC_01190	585394.RHOM_06695	7.69e-95	298.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,sCache_2
ALEKFNDC_01191	180332.JTGN01000001_gene5293	8.12e-05	52.8	COG5492@1|root,COG5492@2|Bacteria,1TQGW@1239|Firmicutes,25END@186801|Clostridia	186801|Clostridia	N	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430
ALEKFNDC_01192	1235793.C809_02957	2.31e-28	102.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,27PJR@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
ALEKFNDC_01194	585394.RHOM_06705	5.14e-116	336.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia	186801|Clostridia	C	PFAM Uncharacterised ACR, YkgG family COG1556	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
ALEKFNDC_01195	622312.ROSEINA2194_03578	0.0	941.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01196	622312.ROSEINA2194_03581	2.65e-190	538.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia	186801|Clostridia	K	CobW P47K family protein	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
ALEKFNDC_01197	585394.RHOM_06720	6.96e-196	546.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
ALEKFNDC_01198	622312.ROSEINA2194_04232	1.64e-131	380.0	COG2703@1|root,COG2703@2|Bacteria,1VBEC@1239|Firmicutes,24NV2@186801|Clostridia	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
ALEKFNDC_01199	622312.ROSEINA2194_00374	2.77e-160	461.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
ALEKFNDC_01200	585394.RHOM_06735	1.78e-179	505.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
ALEKFNDC_01201	585394.RHOM_06740	5.41e-162	457.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
ALEKFNDC_01202	622312.ROSEINA2194_00370	9.43e-202	559.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia	186801|Clostridia	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
ALEKFNDC_01203	585394.RHOM_08835	2.13e-161	457.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
ALEKFNDC_01204	622312.ROSEINA2194_02746	1.32e-20	84.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
ALEKFNDC_01205	622312.ROSEINA2194_02747	5.74e-202	569.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
ALEKFNDC_01206	622312.ROSEINA2194_02748	2.31e-44	147.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
ALEKFNDC_01207	585394.RHOM_08855	2.52e-76	228.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
ALEKFNDC_01208	318464.IO99_03650	2.18e-43	149.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,36FX9@31979|Clostridiaceae	186801|Clostridia	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
ALEKFNDC_01211	622312.ROSEINA2194_02766	1.14e-204	568.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
ALEKFNDC_01212	585394.RHOM_08870	0.0	1098.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
ALEKFNDC_01213	622312.ROSEINA2194_02768	1.98e-141	404.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ALEKFNDC_01214	585394.RHOM_08880	3.52e-136	405.0	COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
ALEKFNDC_01216	585394.RHOM_08885	8.55e-163	468.0	COG1442@1|root,COG1442@2|Bacteria,1U86V@1239|Firmicutes,24CPG@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4422)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4422
ALEKFNDC_01217	622312.ROSEINA2194_02772	8.03e-194	541.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_1_C,Ldh_1_N
ALEKFNDC_01218	622312.ROSEINA2194_02774	0.0	1031.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01219	585394.RHOM_08900	0.0	1135.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01220	622312.ROSEINA2194_02776	8.95e-34	123.0	COG1846@1|root,COG1846@2|Bacteria,1VGEP@1239|Firmicutes,24QRJ@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR
ALEKFNDC_01221	622312.ROSEINA2194_02777	3.85e-101	301.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
ALEKFNDC_01222	585394.RHOM_08915	4.64e-232	640.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
ALEKFNDC_01223	585394.RHOM_08920	8.84e-148	423.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ALEKFNDC_01225	585394.RHOM_08930	2.76e-110	319.0	COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia	186801|Clostridia	L	Hydrolase, nudix family	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05505	NUDIX
ALEKFNDC_01227	585394.RHOM_13875	5.06e-125	362.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia	186801|Clostridia	KT	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE_1	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_01229	622312.ROSEINA2194_01216	1.32e-288	798.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia	186801|Clostridia	M	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
ALEKFNDC_01230	622312.ROSEINA2194_01217	3.11e-76	234.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
ALEKFNDC_01231	622312.ROSEINA2194_01218	2.53e-217	605.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
ALEKFNDC_01233	585394.RHOM_08955	6.1e-53	169.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ALEKFNDC_01234	585394.RHOM_08960	0.0	1029.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
ALEKFNDC_01235	585394.RHOM_08965	4.82e-258	709.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
ALEKFNDC_01236	445971.ANASTE_02333	3.23e-11	75.1	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VDRD@1239|Firmicutes,24QGJ@186801|Clostridia	186801|Clostridia	N	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
ALEKFNDC_01237	556261.HMPREF0240_02065	6.1e-21	92.8	29V64@1|root,30GJS@2|Bacteria,1UG6Z@1239|Firmicutes,24XEW@186801|Clostridia,36PHF@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01238	622312.ROSEINA2194_01221	2.62e-93	283.0	28ZIG@1|root,2ZM9W@2|Bacteria,1V2JN@1239|Firmicutes,25BHX@186801|Clostridia	186801|Clostridia	S	SpoIIIAH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIIAH
ALEKFNDC_01239	622312.ROSEINA2194_01222	2.75e-14	70.1	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AG	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
ALEKFNDC_01240	1449050.JNLE01000003_gene3046	2.66e-90	308.0	COG2207@1|root,COG2207@2|Bacteria,1UZQJ@1239|Firmicutes,24GN0@186801|Clostridia,36HGH@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator, arac family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
ALEKFNDC_01241	1235793.C809_01107	3.07e-201	573.0	COG1680@1|root,COG1680@2|Bacteria,1TSXS@1239|Firmicutes,24H20@186801|Clostridia	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
ALEKFNDC_01242	585394.RHOM_04075	9.67e-177	494.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
ALEKFNDC_01243	585394.RHOM_08205	1.02e-304	837.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia	186801|Clostridia	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ALEKFNDC_01244	585394.RHOM_08210	0.0	872.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
ALEKFNDC_01245	585394.RHOM_08220	2.1e-197	552.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	ccpA	-	-	ko:K02529,ko:K03487	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
ALEKFNDC_01246	585394.RHOM_08225	0.0	883.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia	186801|Clostridia	G	glucuronate isomerase	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
ALEKFNDC_01247	585394.RHOM_08230	5.51e-205	567.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
ALEKFNDC_01248	585394.RHOM_08235	3.84e-145	409.0	COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,249IB@186801|Clostridia	186801|Clostridia	G	Ribose Galactose Isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
ALEKFNDC_01249	1235798.C817_02525	1.12e-08	52.0	2ERI6@1|root,33J3P@2|Bacteria,1VMBI@1239|Firmicutes,24VNP@186801|Clostridia,27VXK@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01250	585394.RHOM_08245	1.01e-81	244.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia	186801|Clostridia	S	Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
ALEKFNDC_01251	622312.ROSEINA2194_01756	4.41e-43	157.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
ALEKFNDC_01252	622312.ROSEINA2194_01757	4.77e-52	166.0	2CSSR@1|root,32SRT@2|Bacteria,1VKAJ@1239|Firmicutes,24N3Y@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01253	585394.RHOM_08260	1.99e-94	276.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ALEKFNDC_01254	585394.RHOM_08265	4.13e-237	666.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia	186801|Clostridia	M	Penicillin-binding Protein	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
ALEKFNDC_01255	585394.RHOM_08270	7.39e-225	632.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
ALEKFNDC_01256	622312.ROSEINA2194_00527	3.3e-311	874.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia	186801|Clostridia	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
ALEKFNDC_01257	585394.RHOM_08280	5.98e-60	189.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
ALEKFNDC_01258	585394.RHOM_08285	4.31e-215	596.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
ALEKFNDC_01259	622312.ROSEINA2194_00524	6.3e-110	320.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
ALEKFNDC_01260	585394.RHOM_08295	6.41e-80	241.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia	186801|Clostridia	S	Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
ALEKFNDC_01261	585394.RHOM_08300	2.69e-41	140.0	COG5341@1|root,COG5341@2|Bacteria	2|Bacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
ALEKFNDC_01262	585394.RHOM_08305	7.11e-301	827.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
ALEKFNDC_01263	585394.RHOM_08310	1.24e-238	664.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
ALEKFNDC_01264	622312.ROSEINA2194_00521	2e-47	160.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia	186801|Clostridia	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
ALEKFNDC_01265	585394.RHOM_08320	1.5e-31	111.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia	186801|Clostridia	S	UPF0291 protein	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
ALEKFNDC_01266	585394.RHOM_08325	1.9e-146	416.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
ALEKFNDC_01267	585394.RHOM_08330	1.53e-172	490.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
ALEKFNDC_01268	585394.RHOM_04115	2.77e-238	663.0	COG5434@1|root,COG5434@2|Bacteria,1TRWY@1239|Firmicutes,24DY3@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01270	585394.RHOM_04105	1.11e-158	448.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia	186801|Clostridia	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
ALEKFNDC_01271	585394.RHOM_04100	2.41e-170	480.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
ALEKFNDC_01272	585394.RHOM_04095	1.03e-224	628.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
ALEKFNDC_01273	1280685.AUKC01000023_gene851	1.99e-183	534.0	COG1653@1|root,COG1653@2|Bacteria,1TQ1D@1239|Firmicutes,24AFW@186801|Clostridia,4BXI8@830|Butyrivibrio	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
ALEKFNDC_01274	1410622.JNKY01000019_gene1714	4.66e-122	379.0	COG2972@1|root,COG2972@2|Bacteria,1UY73@1239|Firmicutes,24AX8@186801|Clostridia,27KZA@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase
ALEKFNDC_01275	1410622.JNKY01000019_gene1711	6.66e-245	685.0	COG3669@1|root,COG3669@2|Bacteria,1TT4V@1239|Firmicutes,24A0S@186801|Clostridia,27IVN@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
ALEKFNDC_01276	1469948.JPNB01000002_gene2802	0.0	1010.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,36FQ1@31979|Clostridiaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
ALEKFNDC_01277	1469948.JPNB01000002_gene2805	1.94e-66	209.0	COG5578@1|root,COG5578@2|Bacteria,1VJNV@1239|Firmicutes,24SDJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
ALEKFNDC_01278	658086.HMPREF0994_06596	0.0	952.0	COG1653@1|root,COG1653@2|Bacteria,1TPHG@1239|Firmicutes,24AFQ@186801|Clostridia,27J6A@186928|unclassified Lachnospiraceae	186801|Clostridia	G	ABC transporter substrate-binding protein	-	-	-	ko:K02027,ko:K17318	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	-
ALEKFNDC_01279	1226325.HMPREF1548_00184	3.1e-203	565.0	COG0395@1|root,COG0395@2|Bacteria,1TRB1@1239|Firmicutes,2488P@186801|Clostridia,36F12@31979|Clostridiaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_01280	1226325.HMPREF1548_00183	2.3e-258	719.0	COG4209@1|root,COG4209@2|Bacteria,1TSTC@1239|Firmicutes,24AFM@186801|Clostridia,36FY9@31979|Clostridiaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ALEKFNDC_01281	622312.ROSEINA2194_02797	1.06e-123	381.0	COG2871@1|root,COG3894@1|root,COG2871@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
ALEKFNDC_01282	411463.EUBVEN_02011	3.87e-160	451.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,25V2W@186806|Eubacteriaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
ALEKFNDC_01283	411463.EUBVEN_02080	3.44e-197	556.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,25UZ8@186806|Eubacteriaceae	186801|Clostridia	E	Aminotransferase, class I	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_01284	658086.HMPREF0994_01119	3.93e-46	149.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,27NQT@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
ALEKFNDC_01285	622312.ROSEINA2194_02260	2.91e-158	447.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia	186801|Clostridia	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
ALEKFNDC_01286	622312.ROSEINA2194_02259	1.67e-80	249.0	COG0850@1|root,COG0850@2|Bacteria,1VAPC@1239|Firmicutes,24MV1@186801|Clostridia	186801|Clostridia	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C
ALEKFNDC_01287	411459.RUMOBE_00194	1.68e-68	215.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
ALEKFNDC_01288	1280698.AUJS01000004_gene2938	3.24e-238	661.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,27URQ@189330|Dorea	186801|Clostridia	C	Biotin and Thiamin Synthesis associated domain	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
ALEKFNDC_01289	537007.BLAHAN_06473	8.97e-150	425.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
ALEKFNDC_01290	1121115.AXVN01000012_gene3091	7.27e-15	68.9	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ALEKFNDC_01291	585394.RHOM_08620	3.1e-199	561.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
ALEKFNDC_01292	585394.RHOM_08625	2.55e-123	354.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia	186801|Clostridia	F	Cytidine monophosphokinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
ALEKFNDC_01294	1235790.C805_01284	7.35e-95	280.0	COG1396@1|root,COG1396@2|Bacteria,1V1K5@1239|Firmicutes,24FTC@186801|Clostridia,25WE3@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	puuR	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3
ALEKFNDC_01295	622312.ROSEINA2194_02729	1.18e-232	643.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
ALEKFNDC_01296	622312.ROSEINA2194_02730	8.71e-159	449.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
ALEKFNDC_01297	622312.ROSEINA2194_02731	1.56e-64	204.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
ALEKFNDC_01298	585394.RHOM_08675	3.34e-182	515.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia	186801|Clostridia	P	ABC transporter, solute-binding protein	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
ALEKFNDC_01299	585394.RHOM_08680	7.96e-110	328.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01300	622312.ROSEINA2194_02735	1.96e-281	778.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	-	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ALEKFNDC_01301	622312.ROSEINA2194_02736	2.15e-91	273.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
ALEKFNDC_01302	622312.ROSEINA2194_03597	1.8e-227	640.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
ALEKFNDC_01303	397288.C806_00845	1.32e-54	172.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,27NDR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
ALEKFNDC_01304	500632.CLONEX_02450	1.61e-82	248.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
ALEKFNDC_01305	585394.RHOM_13805	1.81e-273	750.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia	186801|Clostridia	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
ALEKFNDC_01306	585394.RHOM_13815	7.36e-208	580.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
ALEKFNDC_01309	665956.HMPREF1032_01818	1.47e-27	105.0	COG1695@1|root,COG1695@2|Bacteria,1VHJD@1239|Firmicutes,24QBN@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
ALEKFNDC_01312	585394.RHOM_13820	2.8e-315	859.0	COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia	186801|Clostridia	C	PFAM Acetyl-CoA hydrolase transferase	cat	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
ALEKFNDC_01313	622312.ROSEINA2194_02266	1.14e-60	197.0	2DRS1@1|root,33CTC@2|Bacteria,1VPFR@1239|Firmicutes,24X55@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01315	622312.ROSEINA2194_02264	3.36e-173	486.0	COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,24AH1@186801|Clostridia	186801|Clostridia	V	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_01316	622312.ROSEINA2194_02263	1.93e-67	206.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,24MVE@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
ALEKFNDC_01317	585394.RHOM_13825	4.8e-165	466.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
ALEKFNDC_01318	585394.RHOM_13830	1.45e-133	381.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, beta subunit	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
ALEKFNDC_01319	931626.Awo_c29210	6.64e-68	221.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,25WDP@186806|Eubacteriaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_01320	1042156.CXIVA_05830	3.43e-122	363.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia,36EU6@31979|Clostridiaceae	186801|Clostridia	P	the current gene model (or a revised gene model) may contain a frame shift	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
ALEKFNDC_01321	411468.CLOSCI_02058	5.26e-131	375.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,21XZN@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
ALEKFNDC_01322	1042156.CXIVA_05850	2.88e-127	373.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,36EBM@31979|Clostridiaceae	186801|Clostridia	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
ALEKFNDC_01323	626939.HMPREF9443_01887	6.83e-86	268.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,4H521@909932|Negativicutes	909932|Negativicutes	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
ALEKFNDC_01324	1256908.HMPREF0373_01761	7.91e-82	244.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,25X6H@186806|Eubacteriaceae	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
ALEKFNDC_01325	658088.HMPREF0987_01753	1.02e-108	327.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,27IWC@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
ALEKFNDC_01326	411469.EUBHAL_01351	8.17e-197	551.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,25VS2@186806|Eubacteriaceae	186801|Clostridia	H	Probable molybdopterin binding domain	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
ALEKFNDC_01327	657322.FPR_30730	8.75e-126	365.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
ALEKFNDC_01328	1256908.HMPREF0373_00762	3.84e-29	105.0	29XBV@1|root,30J1M@2|Bacteria,1U4VY@1239|Firmicutes,25NV8@186801|Clostridia,25Z8B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
ALEKFNDC_01329	1235792.C808_01660	5.02e-193	541.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,27JZ4@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
ALEKFNDC_01330	1298920.KI911353_gene785	4.32e-174	496.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z7G@1506553|Lachnoclostridium	186801|Clostridia	E	Cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ALEKFNDC_01331	1256908.HMPREF0373_01402	7.37e-99	293.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,25X3M@186806|Eubacteriaceae	186801|Clostridia	O	DsrE/DsrF-like family	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
ALEKFNDC_01332	1298920.KI911353_gene811	2.79e-76	231.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,21Z3U@1506553|Lachnoclostridium	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
ALEKFNDC_01333	1235793.C809_00618	3.31e-69	213.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,27MYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
ALEKFNDC_01334	585394.RHOM_13845	0.0	1167.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
ALEKFNDC_01335	622312.ROSEINA2194_03257	1.56e-31	110.0	298S6@1|root,2ZVWG@2|Bacteria,1W22G@1239|Firmicutes,256U8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01336	742765.HMPREF9457_03575	1.93e-139	394.0	COG2267@1|root,COG2267@2|Bacteria,1TT75@1239|Firmicutes,25FMP@186801|Clostridia	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
ALEKFNDC_01337	585394.RHOM_12095	1.09e-188	528.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
ALEKFNDC_01338	1410658.JHWI01000034_gene1952	8.88e-178	501.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,3VP1J@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_01339	515620.EUBELI_00113	2.77e-64	201.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,24QSN@186801|Clostridia,25XGV@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
ALEKFNDC_01340	585394.RHOM_03215	3.17e-37	125.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
ALEKFNDC_01341	585394.RHOM_03145	2.47e-103	301.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
ALEKFNDC_01342	585394.RHOM_03140	4.82e-88	260.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
ALEKFNDC_01343	585394.RHOM_03135	1.83e-190	539.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
ALEKFNDC_01344	622312.ROSEINA2194_00699	3.69e-73	225.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
ALEKFNDC_01346	610130.Closa_2435	9.16e-178	511.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,21XK8@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
ALEKFNDC_01347	397287.C807_00819	2.32e-107	314.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,27KNA@186928|unclassified Lachnospiraceae	186801|Clostridia	P	TrkA-N domain	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
ALEKFNDC_01348	585394.RHOM_03075	1.31e-191	541.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
ALEKFNDC_01349	585394.RHOM_03065	3.88e-122	351.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
ALEKFNDC_01350	622312.ROSEINA2194_00695	4.72e-151	426.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia	186801|Clostridia	E	Abc transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
ALEKFNDC_01351	622312.ROSEINA2194_00694	7.24e-163	457.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia	186801|Clostridia	E	Abc transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
ALEKFNDC_01352	622312.ROSEINA2194_00693	3.19e-206	576.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ALEKFNDC_01353	585394.RHOM_03045	4.99e-179	502.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
ALEKFNDC_01354	622312.ROSEINA2194_00691	1.73e-216	606.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia	186801|Clostridia	E	PFAM Extracellular ligand-binding receptor	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
ALEKFNDC_01357	592026.GCWU0000282_003027	5.62e-206	587.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ALEKFNDC_01358	1449050.JNLE01000005_gene4146	7.26e-206	573.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,36DZS@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
ALEKFNDC_01359	1449050.JNLE01000005_gene4147	6.91e-142	431.0	COG1173@1|root,COG5184@1|root,COG1173@2|Bacteria,COG5184@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
ALEKFNDC_01360	592026.GCWU0000282_003030	1.44e-137	400.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ALEKFNDC_01361	1449050.JNLE01000005_gene4149	2.92e-164	491.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae	186801|Clostridia	E	Extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ALEKFNDC_01362	585394.RHOM_02970	2.3e-41	138.0	2C1ED@1|root,33FE6@2|Bacteria,1VKWJ@1239|Firmicutes,24VDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01363	585394.RHOM_08575	9.64e-311	869.0	COG0840@1|root,COG0840@2|Bacteria,1UYFA@1239|Firmicutes,24F3M@186801|Clostridia	186801|Clostridia	NT	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal,PilZ
ALEKFNDC_01364	622312.ROSEINA2194_01478	4.41e-201	582.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,dCache_1,sCache_2
ALEKFNDC_01365	1121115.AXVN01000132_gene727	1.91e-13	66.6	2CUHA@1|root,30KV1@2|Bacteria,1V52Z@1239|Firmicutes,24I1N@186801|Clostridia,3Y1IQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01366	585394.RHOM_11645	1.65e-278	771.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia	186801|Clostridia	H	coproporphyrinogen	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ALEKFNDC_01367	585394.RHOM_11650	3.32e-124	356.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia	186801|Clostridia	P	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
ALEKFNDC_01368	622312.ROSEINA2194_02168	0.0	1385.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
ALEKFNDC_01369	585394.RHOM_11660	1.99e-79	250.0	COG1670@1|root,COG1670@2|Bacteria,1V4FZ@1239|Firmicutes,24PF4@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ALEKFNDC_01370	1410650.JHWL01000003_gene2985	1.55e-47	184.0	28I6K@1|root,2Z89I@2|Bacteria,1UQ1M@1239|Firmicutes,24A0B@186801|Clostridia,4BWIK@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01371	585394.RHOM_04030	9.98e-195	542.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia	186801|Clostridia	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
ALEKFNDC_01372	622312.ROSEINA2194_02248	5.1e-163	458.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
ALEKFNDC_01373	585394.RHOM_04020	1.65e-267	738.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
ALEKFNDC_01374	585394.RHOM_04015	3.2e-155	445.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
ALEKFNDC_01375	585394.RHOM_04015	1.17e-67	218.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
ALEKFNDC_01376	622312.ROSEINA2194_02245	9.38e-145	423.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24HT2@186801|Clostridia	186801|Clostridia	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
ALEKFNDC_01377	1415775.U729_2133	3.04e-74	226.0	COG3153@1|root,COG3153@2|Bacteria,1UK0D@1239|Firmicutes,25FG9@186801|Clostridia,36V06@31979|Clostridiaceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_9
ALEKFNDC_01378	585394.RHOM_05980	1.66e-62	197.0	COG1595@1|root,COG1595@2|Bacteria,1V734@1239|Firmicutes,24MQB@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	sigV	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ALEKFNDC_01379	585394.RHOM_05985	7e-113	336.0	COG5513@1|root,COG5513@2|Bacteria,1UIU3@1239|Firmicutes,25ERV@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3298)	rsiV	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
ALEKFNDC_01380	411902.CLOBOL_02174	2.65e-155	455.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,21Z7N@1506553|Lachnoclostridium	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
ALEKFNDC_01381	742733.HMPREF9469_01435	1.6e-55	188.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia,2201W@1506553|Lachnoclostridium	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_01382	585394.RHOM_04340	6.77e-261	719.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
ALEKFNDC_01383	585394.RHOM_04335	1.02e-83	250.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
ALEKFNDC_01384	485916.Dtox_1961	8.5e-13	78.6	COG3210@1|root,COG3656@1|root,COG5492@1|root,COG3210@2|Bacteria,COG3656@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,267DX@186807|Peptococcaceae	186801|Clostridia	N	PFAM Bacterial Ig-like domain (group 2)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
ALEKFNDC_01385	1235793.C809_03029	1.05e-148	424.0	COG2801@1|root,COG2801@2|Bacteria,1TPEH@1239|Firmicutes,24DNX@186801|Clostridia,27T8M@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
ALEKFNDC_01386	397287.C807_02475	2.65e-54	171.0	COG2963@1|root,COG2963@2|Bacteria,1V9ZX@1239|Firmicutes,24P3X@186801|Clostridia,27RZY@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
ALEKFNDC_01388	526218.Sterm_4199	1.23e-50	174.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
ALEKFNDC_01389	585394.RHOM_04285	1.53e-245	674.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
ALEKFNDC_01390	622312.ROSEINA2194_04459	5.14e-225	622.0	COG0524@1|root,COG0524@2|Bacteria,1TQ9Q@1239|Firmicutes,25B0T@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
ALEKFNDC_01391	585394.RHOM_04000	2.34e-24	100.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia	186801|Clostridia	E	PFAM Peptidase M19, renal dipeptidase	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
ALEKFNDC_01392	397288.C806_03378	1.61e-159	474.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,27KAK@186928|unclassified Lachnospiraceae	186801|Clostridia	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,dCache_1
ALEKFNDC_01393	622312.ROSEINA2194_02490	2.27e-58	185.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
ALEKFNDC_01394	585394.RHOM_08120	8.1e-144	412.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
ALEKFNDC_01395	585394.RHOM_08125	3.83e-130	376.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ALEKFNDC_01396	585394.RHOM_08130	0.0	1185.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia	186801|Clostridia	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
ALEKFNDC_01397	622312.ROSEINA2194_01001	4.06e-278	771.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia	186801|Clostridia	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
ALEKFNDC_01398	585394.RHOM_08140	6.02e-263	726.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia	186801|Clostridia	E	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
ALEKFNDC_01399	585394.RHOM_08145	1.67e-217	606.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
ALEKFNDC_01400	622312.ROSEINA2194_00998	4.03e-103	313.0	COG0823@1|root,COG0823@2|Bacteria,1V60E@1239|Firmicutes,24I0N@186801|Clostridia	186801|Clostridia	U	Domain of unknown function (DUF5050)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5050
ALEKFNDC_01401	622312.ROSEINA2194_00997	0.0	2603.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
ALEKFNDC_01402	585394.RHOM_07195	9.54e-226	625.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia	186801|Clostridia	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
ALEKFNDC_01403	622312.ROSEINA2194_00995	1.41e-190	535.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia	186801|Clostridia	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
ALEKFNDC_01404	585394.RHOM_07185	3.87e-207	580.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
ALEKFNDC_01405	622312.ROSEINA2194_00993	1.79e-148	422.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia	186801|Clostridia	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
ALEKFNDC_01406	585394.RHOM_07175	6.25e-111	323.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
ALEKFNDC_01407	622312.ROSEINA2194_00991	3.3e-107	311.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
ALEKFNDC_01408	585394.RHOM_07165	2.35e-151	427.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
ALEKFNDC_01409	622312.ROSEINA2194_00989	1.24e-78	246.0	COG1664@1|root,COG1664@2|Bacteria,1TS93@1239|Firmicutes,24DZX@186801|Clostridia	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
ALEKFNDC_01410	622312.ROSEINA2194_00988	8.49e-149	428.0	COG0726@1|root,COG0726@2|Bacteria,1V1X7@1239|Firmicutes,25B6U@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ALEKFNDC_01411	1410626.JHXB01000007_gene2561	6.36e-84	260.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia,27KSJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF368)	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
ALEKFNDC_01412	742738.HMPREF9460_03797	7.35e-222	631.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,2681R@186813|unclassified Clostridiales	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
ALEKFNDC_01413	585394.RHOM_01235	0.0	910.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
ALEKFNDC_01414	585394.RHOM_04975	4.32e-76	235.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
ALEKFNDC_01415	585394.RHOM_04970	5.48e-218	606.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
ALEKFNDC_01416	1123313.ATUT01000016_gene618	4.57e-39	149.0	COG1835@1|root,COG1835@2|Bacteria,1UXXI@1239|Firmicutes,3VQ6J@526524|Erysipelotrichia	526524|Erysipelotrichia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_01417	411459.RUMOBE_02728	1.58e-193	586.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
ALEKFNDC_01419	622312.ROSEINA2194_02532	1.26e-138	416.0	28PI9@1|root,2ZC8C@2|Bacteria,1V36K@1239|Firmicutes,24K4U@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
ALEKFNDC_01420	585394.RHOM_06285	0.0	958.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
ALEKFNDC_01421	585394.RHOM_06280	5.23e-86	263.0	2BFV8@1|root,329QI@2|Bacteria,1V7DP@1239|Firmicutes,24KD4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01422	585394.RHOM_06275	2.1e-124	360.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
ALEKFNDC_01424	622312.ROSEINA2194_02810	9.75e-202	560.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
ALEKFNDC_01425	622312.ROSEINA2194_02811	0.0	1395.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes	1239|Firmicutes	S	Peptidase M16 inactive domain protein	hypA2	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
ALEKFNDC_01426	585394.RHOM_06255	7.54e-40	132.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ALEKFNDC_01427	585394.RHOM_06250	5.63e-153	437.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia	186801|Clostridia	M	mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
ALEKFNDC_01428	585394.RHOM_06245	2.15e-234	652.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
ALEKFNDC_01429	585394.RHOM_06240	2.37e-254	700.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ALEKFNDC_01430	585394.RHOM_06235	1.55e-255	701.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ALEKFNDC_01431	622312.ROSEINA2194_02815	0.0	960.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ALEKFNDC_01432	585394.RHOM_06225	0.0	1073.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
ALEKFNDC_01433	622312.ROSEINA2194_02817	3.74e-245	675.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ALEKFNDC_01434	1292035.H476_3442	3.73e-89	293.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,25SIQ@186804|Peptostreptococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01437	622312.ROSEINA2194_01224	9.72e-124	369.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AE	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
ALEKFNDC_01438	585394.RHOM_09090	2.48e-45	150.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AD	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
ALEKFNDC_01439	585394.RHOM_09095	1.58e-33	115.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia	186801|Clostridia	S	Stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
ALEKFNDC_01440	397290.C810_02092	4.22e-10	63.2	29N29@1|root,30900@2|Bacteria,1U486@1239|Firmicutes,24GD0@186801|Clostridia,27PVV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Stage III sporulation protein AB (spore_III_AB)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AB
ALEKFNDC_01441	585394.RHOM_09105	3.73e-125	367.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
ALEKFNDC_01442	483218.BACPEC_01486	5.25e-184	518.0	28JHK@1|root,2Z9B4@2|Bacteria,1TS7Y@1239|Firmicutes,249S0@186801|Clostridia,26AQK@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01443	742765.HMPREF9457_01596	0.0	890.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,27WC8@189330|Dorea	186801|Clostridia	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
ALEKFNDC_01444	411489.CLOL250_01411	2.84e-62	201.0	2EX79@1|root,33QI5@2|Bacteria,1VS8K@1239|Firmicutes,24YCQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01445	622312.ROSEINA2194_01230	1.78e-216	611.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ALEKFNDC_01446	585394.RHOM_09110	6.58e-133	394.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia	186801|Clostridia	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
ALEKFNDC_01447	592026.GCWU0000282_000636	1.82e-124	366.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ALEKFNDC_01448	877421.AUJT01000002_gene1169	4.84e-108	322.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,27K6U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
ALEKFNDC_01449	1121296.JONJ01000003_gene758	1.1e-220	620.0	COG0644@1|root,COG0644@2|Bacteria,1TR0D@1239|Firmicutes,24BE3@186801|Clostridia,21ZUQ@1506553|Lachnoclostridium	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
ALEKFNDC_01450	997346.HMPREF9374_0063	3.35e-17	86.3	2AG0K@1|root,3164N@2|Bacteria,1V7CN@1239|Firmicutes,4HSP9@91061|Bacilli,27C2K@186824|Thermoactinomycetaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01451	1121296.JONJ01000003_gene756	0.0	1025.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,21YSM@1506553|Lachnoclostridium	186801|Clostridia	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
ALEKFNDC_01452	1111135.HMPREF1248_0984	5.41e-210	591.0	COG2610@1|root,COG2610@2|Bacteria,2I7H9@201174|Actinobacteria	201174|Actinobacteria	EG	gluconate transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01453	877421.AUJT01000002_gene1161	9.69e-123	354.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,27JDF@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
ALEKFNDC_01454	1235802.C823_05151	2.67e-72	221.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,25WR7@186806|Eubacteriaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
ALEKFNDC_01455	1235802.C823_04319	2.14e-48	159.0	COG0681@1|root,COG0681@2|Bacteria,1VFKY@1239|Firmicutes,24RQG@186801|Clostridia,25XJH@186806|Eubacteriaceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
ALEKFNDC_01456	411469.EUBHAL_02535	2.58e-85	272.0	2DBZW@1|root,2ZC46@2|Bacteria,1V2V4@1239|Firmicutes,24H1D@186801|Clostridia	186801|Clostridia	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
ALEKFNDC_01457	585394.RHOM_08700	0.0	931.0	COG1132@1|root,COG1132@2|Bacteria,1TRJF@1239|Firmicutes,249CN@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01458	585394.RHOM_08710	2.66e-54	172.0	28V59@1|root,2ZH8H@2|Bacteria,1W3K5@1239|Firmicutes,255DA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01459	585394.RHOM_08705	1.16e-52	169.0	2BZS0@1|root,343DQ@2|Bacteria,1VZ4U@1239|Firmicutes,25450@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01460	411460.RUMTOR_01146	1.42e-20	90.9	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3XZ24@572511|Blautia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ALEKFNDC_01461	585394.RHOM_08720	6.95e-166	482.0	2DBEW@1|root,2Z8UY@2|Bacteria,1UYFJ@1239|Firmicutes,2489J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
ALEKFNDC_01462	585394.RHOM_08730	2.7e-140	413.0	COG2244@1|root,COG2244@2|Bacteria,1V0I3@1239|Firmicutes,24F2V@186801|Clostridia	186801|Clostridia	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
ALEKFNDC_01463	585394.RHOM_08735	1.87e-250	701.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
ALEKFNDC_01465	585394.RHOM_03830	5.08e-290	805.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ALEKFNDC_01466	622312.ROSEINA2194_01915	1.91e-43	168.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
ALEKFNDC_01467	585394.RHOM_03825	3.19e-282	783.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
ALEKFNDC_01469	622312.ROSEINA2194_00348	5.11e-155	439.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
ALEKFNDC_01470	585394.RHOM_03805	7.34e-222	612.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
ALEKFNDC_01471	585394.RHOM_03800	1.34e-91	268.0	COG0537@1|root,COG0537@2|Bacteria,1V3BE@1239|Firmicutes,24H73@186801|Clostridia	186801|Clostridia	FG	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HIT
ALEKFNDC_01472	622312.ROSEINA2194_00584	1.5e-67	206.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
ALEKFNDC_01473	585394.RHOM_03740	1.14e-190	535.0	COG0183@1|root,COG0183@2|Bacteria,1UHVW@1239|Firmicutes,248BM@186801|Clostridia	186801|Clostridia	I	stage v sporulation protein ad	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
ALEKFNDC_01475	622312.ROSEINA2194_00581	7.97e-37	129.0	COG1476@1|root,COG1476@2|Bacteria,1VCHW@1239|Firmicutes,24TP0@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01476	622312.ROSEINA2194_03332	1.04e-224	642.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia	186801|Clostridia	M	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
ALEKFNDC_01477	585394.RHOM_11030	7.5e-129	370.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
ALEKFNDC_01478	1408324.JNJK01000005_gene1128	4.99e-194	551.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,27JK2@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ALEKFNDC_01479	622312.ROSEINA2194_03329	3.99e-260	715.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
ALEKFNDC_01480	622312.ROSEINA2194_03328	0.0	1023.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
ALEKFNDC_01481	622312.ROSEINA2194_03327	1.29e-168	475.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
ALEKFNDC_01482	585394.RHOM_04475	1.79e-129	374.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
ALEKFNDC_01483	585394.RHOM_04470	8.69e-184	519.0	28JB6@1|root,2Z960@2|Bacteria,1U83T@1239|Firmicutes,24BAY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01484	585394.RHOM_04465	1.46e-101	295.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia	186801|Clostridia	E	acetolactate synthase, small	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
ALEKFNDC_01485	585394.RHOM_04460	0.0	1078.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia	186801|Clostridia	H	Acetolactate synthase, large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
ALEKFNDC_01486	585394.RHOM_04455	2.22e-194	543.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
ALEKFNDC_01487	585394.RHOM_04450	5.97e-98	286.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
ALEKFNDC_01488	585394.RHOM_04440	2.66e-30	108.0	2DRX4@1|root,33DGR@2|Bacteria,1VKQ3@1239|Firmicutes,24URP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01489	585394.RHOM_04435	1.48e-66	206.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01490	1469948.JPNB01000001_gene446	4.81e-143	442.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,36E1W@31979|Clostridiaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
ALEKFNDC_01492	585394.RHOM_04710	9.72e-157	445.0	COG2035@1|root,COG2035@2|Bacteria,1UYD5@1239|Firmicutes,24B08@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K08974	-	-	-	-	ko00000	-	-	-	DUF368
ALEKFNDC_01493	622312.ROSEINA2194_02642	0.0	892.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01494	585394.RHOM_04720	0.0	940.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01495	622312.ROSEINA2194_02159	4.96e-99	295.0	COG2186@1|root,COG2186@2|Bacteria,1V1Y0@1239|Firmicutes,249UW@186801|Clostridia	186801|Clostridia	K	FCD domain	pdhR	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
ALEKFNDC_01496	556261.HMPREF0240_00860	2.02e-152	455.0	COG2199@1|root,COG2199@2|Bacteria,1TQKY@1239|Firmicutes,25EP8@186801|Clostridia,36V2W@31979|Clostridiaceae	186801|Clostridia	T	Pfam:Cache_1	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP,dCache_1
ALEKFNDC_01497	585394.RHOM_11415	2.91e-115	351.0	COG0840@1|root,COG0840@2|Bacteria,1TQW8@1239|Firmicutes,24EE8@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
ALEKFNDC_01498	585394.RHOM_11560	1.38e-239	674.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
ALEKFNDC_01499	397287.C807_00219	2.66e-83	254.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,27U4Q@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT,Response_reg
ALEKFNDC_01500	622312.ROSEINA2194_02885	3.97e-204	573.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia	186801|Clostridia	E	Aminotransferase	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
ALEKFNDC_01501	622312.ROSEINA2194_02884	1.12e-95	282.0	COG4720@1|root,COG4720@2|Bacteria,1V1E7@1239|Firmicutes,25CJR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
ALEKFNDC_01502	622312.ROSEINA2194_02871	4.53e-41	135.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
ALEKFNDC_01503	585394.RHOM_11385	2.43e-76	232.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01504	585394.RHOM_11380	2.17e-235	656.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia	186801|Clostridia	E	M18 family aminopeptidase	-	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
ALEKFNDC_01505	622312.ROSEINA2194_02860	6.25e-126	377.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia	186801|Clostridia	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
ALEKFNDC_01506	585394.RHOM_11375	2.15e-164	464.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
ALEKFNDC_01507	585394.RHOM_11370	2.48e-174	502.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
ALEKFNDC_01508	622312.ROSEINA2194_02856	7.83e-229	641.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
ALEKFNDC_01509	585394.RHOM_11360	2.27e-122	359.0	COG2755@1|root,COG2755@2|Bacteria,1V2MD@1239|Firmicutes,24FWG@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_01511	457415.HMPREF1006_00874	2.31e-113	359.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,3TB48@508458|Synergistetes	508458|Synergistetes	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS,Response_reg
ALEKFNDC_01512	585394.RHOM_11345	2.21e-248	690.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
ALEKFNDC_01513	622312.ROSEINA2194_00725	2.58e-32	114.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes	1239|Firmicutes	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
ALEKFNDC_01514	622312.ROSEINA2194_00724	0.0	1217.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
ALEKFNDC_01515	585394.RHOM_11330	1.56e-98	287.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
ALEKFNDC_01516	483218.BACPEC_01206	2.3e-232	647.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,2683I@186813|unclassified Clostridiales	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Cys_Met_Meta_PP
ALEKFNDC_01517	483218.BACPEC_01205	1.33e-168	475.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,269QP@186813|unclassified Clostridiales	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	-	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
ALEKFNDC_01518	483218.BACPEC_01204	2.7e-45	147.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia	186801|Clostridia	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
ALEKFNDC_01519	483218.BACPEC_01203	1.81e-42	141.0	COG0526@1|root,COG0526@2|Bacteria,1UHN6@1239|Firmicutes,25FT1@186801|Clostridia	186801|Clostridia	O	Thioredoxin	trxA1	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
ALEKFNDC_01520	483218.BACPEC_01202	2.65e-29	105.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia	186801|Clostridia	H	thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
ALEKFNDC_01521	483218.BACPEC_01201	4.81e-183	510.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,269P8@186813|unclassified Clostridiales	186801|Clostridia	H	ThiF family	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
ALEKFNDC_01522	1160721.RBI_I01804	2.66e-56	179.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
ALEKFNDC_01523	180332.JTGN01000013_gene974	1.45e-32	145.0	COG2340@1|root,COG3087@1|root,COG3507@1|root,COG3533@1|root,COG2340@2|Bacteria,COG3087@2|Bacteria,COG3507@2|Bacteria,COG3533@2|Bacteria,1TRV9@1239|Firmicutes,24CKP@186801|Clostridia	186801|Clostridia	G	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
ALEKFNDC_01524	1449050.JNLE01000003_gene2095	3.15e-21	109.0	COG0304@1|root,COG2273@1|root,COG2340@1|root,COG3291@1|root,COG0304@2|Bacteria,COG2273@2|Bacteria,COG2340@2|Bacteria,COG3291@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,36HJG@31979|Clostridiaceae	186801|Clostridia	G	family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,DUF1533,Glyco_hydro_16,SLH
ALEKFNDC_01525	483218.BACPEC_00641	8.69e-114	333.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia,26CP4@186813|unclassified Clostridiales	186801|Clostridia	K	TipAS antibiotic-recognition domain	mta	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
ALEKFNDC_01527	1408312.JNJS01000004_gene2495	7.95e-149	425.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ALEKFNDC_01528	622312.ROSEINA2194_00812	4.47e-35	120.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
ALEKFNDC_01529	585394.RHOM_14080	1.23e-179	505.0	COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,24831@186801|Clostridia	186801|Clostridia	S	reductase II	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iHN637.CLJU_RS20775	NMO
ALEKFNDC_01530	622312.ROSEINA2194_00810	1.06e-151	435.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia	186801|Clostridia	I	malonyl coa-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
ALEKFNDC_01531	476272.RUMHYD_01858	2.15e-115	337.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
ALEKFNDC_01532	585394.RHOM_14065	1.84e-243	675.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
ALEKFNDC_01533	622312.ROSEINA2194_00807	4.38e-80	239.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
ALEKFNDC_01534	585394.RHOM_14055	0.0	942.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
ALEKFNDC_01535	622312.ROSEINA2194_00805	1.28e-166	473.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
ALEKFNDC_01537	585394.RHOM_14045	9.97e-77	231.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
ALEKFNDC_01538	622312.ROSEINA2194_02852	1.35e-176	498.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia	186801|Clostridia	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
ALEKFNDC_01539	518637.EUBIFOR_00314	7.19e-31	108.0	2BEFR@1|root,33CRA@2|Bacteria,1VQ4D@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01540	1256908.HMPREF0373_03376	9.56e-75	225.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,25XHU@186806|Eubacteriaceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
ALEKFNDC_01541	585394.RHOM_02660	1.78e-33	126.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_01542	585394.RHOM_02665	8.93e-164	462.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,24DNI@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_01543	585394.RHOM_14040	3.88e-42	139.0	2C5I7@1|root,330HE@2|Bacteria,1VJU8@1239|Firmicutes,24SCX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
ALEKFNDC_01544	1235790.C805_03587	2.17e-117	356.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24GB5@186801|Clostridia,25WC7@186806|Eubacteriaceae	186801|Clostridia	N	hydrolase, family 25	-	-	-	-	-	-	-	-	-	-	-	-	CAP,SLH
ALEKFNDC_01545	397290.C810_05214	1.26e-74	225.0	2EDIT@1|root,337EP@2|Bacteria,1VH4F@1239|Firmicutes,24TXZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01546	397290.C810_01328	3.48e-36	137.0	28PRN@1|root,2ZCDE@2|Bacteria,1V21V@1239|Firmicutes,24H7E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01548	658655.HMPREF0988_00919	1.6e-38	136.0	2BY5S@1|root,2ZR30@2|Bacteria,1W23Z@1239|Firmicutes,256HP@186801|Clostridia,27SD3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01551	585394.RHOM_11225	7.02e-125	381.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia	186801|Clostridia	E	MeTHIonine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
ALEKFNDC_01552	622312.ROSEINA2194_00800	0.0	897.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia	186801|Clostridia	E	MeTHIonine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
ALEKFNDC_01553	622312.ROSEINA2194_01929	4.41e-231	639.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
ALEKFNDC_01554	585394.RHOM_11245	8.06e-77	240.0	COG1345@1|root,COG1345@2|Bacteria,1V9AS@1239|Firmicutes,24MHW@186801|Clostridia	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01555	622312.ROSEINA2194_01931	6.12e-156	438.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
ALEKFNDC_01556	622312.ROSEINA2194_01932	1.87e-170	477.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ALEKFNDC_01557	622312.ROSEINA2194_01933	3.58e-115	333.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ALEKFNDC_01558	622312.ROSEINA2194_01934	3.23e-43	166.0	2DM0G@1|root,31677@2|Bacteria,1UIGR@1239|Firmicutes,25EN6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01559	585394.RHOM_11275	2.2e-198	551.0	COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheV	-	2.7.13.3	ko:K03407,ko:K03415	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,Response_reg
ALEKFNDC_01561	1235790.C805_02256	1.08e-26	110.0	2C0VN@1|root,32VTP@2|Bacteria,1VAWW@1239|Firmicutes,24N54@186801|Clostridia,25XSI@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4352
ALEKFNDC_01562	622312.ROSEINA2194_01937	1.78e-252	706.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_01563	1235802.C823_02421	2.69e-136	389.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,25UU1@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_01564	622312.ROSEINA2194_01939	6.29e-53	176.0	2DSWH@1|root,32UTX@2|Bacteria,1VBEP@1239|Firmicutes,24PR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01565	1469948.JPNB01000001_gene964	4.37e-251	696.0	COG1501@1|root,COG1501@2|Bacteria,1UJ1V@1239|Firmicutes,24AVU@186801|Clostridia,36HI8@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
ALEKFNDC_01566	1469948.JPNB01000002_gene3625	0.0	1009.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,36FIY@31979|Clostridiaceae	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
ALEKFNDC_01567	585394.RHOM_04085	0.0	1028.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23,3.2.1.31	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01105,R01478,R01678,R03355,R04783,R04979,R06114,R07818,R08127,R08260,R10830	RC00049,RC00055,RC00171,RC00452,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_01568	1469948.JPNB01000002_gene3623	1.56e-153	449.0	COG3507@1|root,COG5492@1|root,COG3507@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Glyco_hydro_43,Laminin_G_3
ALEKFNDC_01569	1469948.JPNB01000002_gene3621	0.0	963.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia,36E91@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
ALEKFNDC_01570	1280676.AUJO01000001_gene2223	2.36e-314	866.0	COG1653@1|root,COG1653@2|Bacteria,1TR5P@1239|Firmicutes,24F0C@186801|Clostridia,4C20R@830|Butyrivibrio	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502,SBP_bac_1
ALEKFNDC_01571	1280685.AUKC01000052_gene1365	1.76e-177	499.0	COG0395@1|root,COG0395@2|Bacteria,1TS9S@1239|Firmicutes,24BF3@186801|Clostridia,4BWPH@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_01572	1280673.AUJJ01000002_gene2714	1.37e-82	252.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia,4BW6J@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_01573	585394.RHOM_10595	4.75e-134	386.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01574	585394.RHOM_10580	1.28e-281	774.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
ALEKFNDC_01575	1519439.JPJG01000076_gene865	9.16e-29	115.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,2N8QT@216572|Oscillospiraceae	186801|Clostridia	O	Uncharacterized protein family (UPF0051)	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
ALEKFNDC_01576	1235800.C819_01897	7.82e-133	380.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,27IBR@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_01577	658086.HMPREF0994_04912	2.7e-275	804.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,27IXQ@186928|unclassified Lachnospiraceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ALEKFNDC_01578	585394.RHOM_04695	2.95e-116	335.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	cmk	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
ALEKFNDC_01579	622312.ROSEINA2194_02909	2.92e-118	348.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia	186801|Clostridia	P	transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ALEKFNDC_01580	1280390.CBQR020000077_gene1694	4.85e-121	354.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,4HAFM@91061|Bacilli,26QI3@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
ALEKFNDC_01581	663278.Ethha_1750	3.61e-104	311.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3WHIC@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ALEKFNDC_01582	1232443.BAIA02000064_gene1097	3.01e-128	377.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
ALEKFNDC_01583	585394.RHOM_13210	5.79e-37	125.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01584	622312.ROSEINA2194_02907	0.0	1157.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
ALEKFNDC_01585	585394.RHOM_13205	1.32e-72	222.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24IND@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01586	585394.RHOM_13200	0.0	1152.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
ALEKFNDC_01587	585394.RHOM_13195	2.9e-47	152.0	COG1925@1|root,COG1925@2|Bacteria,1UFZA@1239|Firmicutes,24MM8@186801|Clostridia	186801|Clostridia	G	Phosphocarrier protein (Hpr)	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
ALEKFNDC_01588	622312.ROSEINA2194_02903	2.05e-32	121.0	2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01589	585394.RHOM_13185	6.04e-271	743.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia	186801|Clostridia	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
ALEKFNDC_01590	585394.RHOM_13180	1.12e-173	491.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
ALEKFNDC_01591	622312.ROSEINA2194_03797	5.86e-142	414.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
ALEKFNDC_01592	622312.ROSEINA2194_03795	2.7e-285	785.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ALEKFNDC_01593	585394.RHOM_13160	6.35e-262	722.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
ALEKFNDC_01594	585394.RHOM_13155	2.53e-246	679.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia	186801|Clostridia	G	glucose-1-phosphate adenylyltransferase GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
ALEKFNDC_01595	622312.ROSEINA2194_01451	1.19e-50	160.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
ALEKFNDC_01596	883109.HMPREF0380_01476	2.18e-62	192.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3WDDV@538999|Clostridiales incertae sedis	186801|Clostridia	P	ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
ALEKFNDC_01597	411474.COPEUT_00684	2.57e-79	241.0	COG1102@1|root,COG1102@2|Bacteria,1V4ZA@1239|Firmicutes	1239|Firmicutes	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
ALEKFNDC_01598	1280694.AUJQ01000020_gene6	1.81e-55	178.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia	186801|Clostridia	C	Bacterial transferase hexapeptide	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
ALEKFNDC_01599	622312.ROSEINA2194_03515	7.23e-129	395.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
ALEKFNDC_01600	411462.DORLON_02338	1.51e-296	810.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,27UZZ@189330|Dorea	186801|Clostridia	H	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
ALEKFNDC_01601	585394.RHOM_13220	0.0	1054.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ALEKFNDC_01602	97139.C824_03803	3.31e-43	151.0	28M3R@1|root,32UZU@2|Bacteria,1VBVW@1239|Firmicutes,24J58@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01603	1280676.AUJO01000002_gene1714	2.96e-16	80.9	28M3R@1|root,2ZAHU@2|Bacteria,1TR3Y@1239|Firmicutes,249MC@186801|Clostridia,4BZHD@830|Butyrivibrio	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01604	1121115.AXVN01000018_gene43	5.04e-149	432.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
ALEKFNDC_01605	457412.RSAG_01638	2.25e-201	563.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
ALEKFNDC_01606	457412.RSAG_01637	2.63e-169	479.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3WJ19@541000|Ruminococcaceae	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
ALEKFNDC_01607	397288.C806_01988	6.43e-97	286.0	COG0705@1|root,COG0705@2|Bacteria,1V1C3@1239|Firmicutes,24GPR@186801|Clostridia,27KQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid
ALEKFNDC_01608	1121115.AXVN01000018_gene46	0.0	1168.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
ALEKFNDC_01609	1121115.AXVN01000018_gene47	1.07e-207	582.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
ALEKFNDC_01610	397291.C804_02843	3.31e-123	352.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,27K57@186928|unclassified Lachnospiraceae	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
ALEKFNDC_01611	1121115.AXVN01000018_gene50	5.68e-113	327.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
ALEKFNDC_01612	1121115.AXVN01000018_gene51	0.0	1407.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
ALEKFNDC_01613	1235799.C818_01135	1.15e-93	283.0	COG0561@1|root,COG0561@2|Bacteria,1V24C@1239|Firmicutes,24HGT@186801|Clostridia,27N1C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	hydrolases of the HAD superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3,S6PP
ALEKFNDC_01614	575593.HMPREF0491_01365	2.22e-130	374.0	COG2013@1|root,COG2013@2|Bacteria,1TSVH@1239|Firmicutes,24DQR@186801|Clostridia,27JVP@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
ALEKFNDC_01615	679200.HMPREF9333_01426	1.34e-87	268.0	COG2310@1|root,COG2310@2|Bacteria,1V26C@1239|Firmicutes,24GMA@186801|Clostridia	186801|Clostridia	T	TerD domain	-	-	-	-	-	-	-	-	-	-	-	-	TerD
ALEKFNDC_01616	1121115.AXVN01000114_gene1668	2.86e-77	233.0	COG1671@1|root,COG1671@2|Bacteria,1TTTR@1239|Firmicutes,25NB2@186801|Clostridia,3Y1Q7@572511|Blautia	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	-	-	-	-	-	-	-	-	-	DUF188
ALEKFNDC_01617	397291.C804_02030	2.64e-284	815.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,27JAC@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_01623	476272.RUMHYD_02827	1.04e-21	86.7	COG1974@1|root,COG1974@2|Bacteria	2|Bacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	HTH_3,LexA_DNA_bind,Peptidase_S24
ALEKFNDC_01624	693746.OBV_43290	1.04e-19	90.5	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	higA	GO:0008150,GO:0009636,GO:0042221,GO:0050896	-	ko:K07334,ko:K18831,ko:K21498	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3,Peptidase_M78
ALEKFNDC_01625	478749.BRYFOR_05407	9.83e-90	283.0	COG0582@1|root,COG0582@2|Bacteria,1V16B@1239|Firmicutes,24CY2@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
ALEKFNDC_01626	140626.JHWB01000022_gene2115	6.15e-99	293.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
ALEKFNDC_01627	585394.RHOM_14265	2.44e-219	635.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
ALEKFNDC_01628	1256908.HMPREF0373_02016	1.54e-144	412.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_01629	585394.RHOM_14275	3.43e-103	314.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ALEKFNDC_01630	1235793.C809_02063	5.49e-123	354.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,27IZY@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	graR	-	-	ko:K19082	ko02020,map02020	M00734,M00737	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_01631	585394.RHOM_14285	6.01e-226	625.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
ALEKFNDC_01632	585394.RHOM_15710	8.66e-143	424.0	COG3103@1|root,COG3773@1|root,COG3103@2|Bacteria,COG3773@2|Bacteria,1TRFW@1239|Firmicutes,24DDK@186801|Clostridia	186801|Clostridia	MT	Cell Wall Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_2,SH3_3
ALEKFNDC_01634	585394.RHOM_15725	1.15e-211	590.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
ALEKFNDC_01635	622312.ROSEINA2194_00772	3.52e-85	252.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia	186801|Clostridia	FG	PFAM Histidine triad (HIT) protein	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
ALEKFNDC_01636	585394.RHOM_15740	2.5e-200	559.0	COG0655@1|root,COG3255@1|root,COG0655@2|Bacteria,COG3255@2|Bacteria,1TT0Y@1239|Firmicutes,247MH@186801|Clostridia	186801|Clostridia	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
ALEKFNDC_01637	622312.ROSEINA2194_00769	1.22e-155	447.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
ALEKFNDC_01638	585394.RHOM_15750	1.79e-72	238.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia	186801|Clostridia	T	(FHA) domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
ALEKFNDC_01641	622312.ROSEINA2194_00764	2.27e-67	217.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
ALEKFNDC_01642	585394.RHOM_15770	7.23e-105	329.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01643	397287.C807_03605	8.06e-11	58.2	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,27QCR@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
ALEKFNDC_01644	622312.ROSEINA2194_00761	1.53e-92	292.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
ALEKFNDC_01645	585394.RHOM_15785	6.63e-78	242.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
ALEKFNDC_01646	585394.RHOM_15790	3.82e-33	125.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia	186801|Clostridia	U	Type II IV secretion system protein	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ALEKFNDC_01648	622312.ROSEINA2194_03514	1.8e-248	723.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
ALEKFNDC_01652	397288.C806_03858	4.48e-19	82.8	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24TDP@186801|Clostridia,27QMZ@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01653	585394.RHOM_05230	2.39e-160	473.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01654	585394.RHOM_05225	6.79e-189	532.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ALEKFNDC_01657	622312.ROSEINA2194_00296	1.37e-157	447.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
ALEKFNDC_01658	515620.EUBELI_00188	1.8e-46	153.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,25VK4@186806|Eubacteriaceae	186801|Clostridia	S	conserved protein, contains double-stranded beta-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,CMD,Cupin_2
ALEKFNDC_01659	1235790.C805_03449	6.8e-49	157.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,25WII@186806|Eubacteriaceae	186801|Clostridia	S	Belongs to the UPF0145 family	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
ALEKFNDC_01660	1232447.BAHW02000009_gene403	1.31e-07	51.2	2ENA7@1|root,33FXX@2|Bacteria,1VMBP@1239|Firmicutes,24USY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01661	1449050.JNLE01000005_gene4440	3.3e-113	343.0	COG0727@1|root,COG0727@2|Bacteria,1UZ5G@1239|Firmicutes,25GD9@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised protein family (UPF0153)	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	-
ALEKFNDC_01662	585394.RHOM_06120	0.0	921.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
ALEKFNDC_01663	585394.RHOM_06110	6.82e-254	704.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_01664	585394.RHOM_06105	4.28e-155	444.0	COG0760@1|root,COG0760@2|Bacteria,1V8DP@1239|Firmicutes,24F9F@186801|Clostridia	186801|Clostridia	O	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3
ALEKFNDC_01665	585394.RHOM_06100	0.0	884.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia	186801|Clostridia	S	'oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
ALEKFNDC_01666	397290.C810_03072	2.71e-37	127.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,27P0I@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01667	622312.ROSEINA2194_01555	1.86e-102	301.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
ALEKFNDC_01668	585394.RHOM_06085	0.0	1500.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
ALEKFNDC_01669	622312.ROSEINA2194_01559	0.0	1480.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia	186801|Clostridia	L	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
ALEKFNDC_01671	713605.ADHG01000006_gene763	5.54e-73	223.0	COG1670@1|root,COG1670@2|Bacteria,1UHY0@1239|Firmicutes,4ISAD@91061|Bacilli,3FBRT@33958|Lactobacillaceae	91061|Bacilli	J	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ALEKFNDC_01672	1235802.C823_04091	5.95e-56	182.0	COG3755@1|root,COG3755@2|Bacteria,1VHSS@1239|Firmicutes,24U0W@186801|Clostridia	186801|Clostridia	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
ALEKFNDC_01673	585394.RHOM_07820	8e-150	428.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
ALEKFNDC_01674	585394.RHOM_07825	2.58e-125	360.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia	186801|Clostridia	OU	Protease subunit of ATP-dependent	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
ALEKFNDC_01675	585394.RHOM_07830	0.0	920.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
ALEKFNDC_01676	585394.RHOM_07835	4.31e-150	424.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia	186801|Clostridia	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
ALEKFNDC_01677	585394.RHOM_07845	2.16e-70	213.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
ALEKFNDC_01678	622312.ROSEINA2194_03813	1.54e-212	595.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
ALEKFNDC_01679	622312.ROSEINA2194_03814	5.59e-76	246.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
ALEKFNDC_01680	585394.RHOM_07850	1.08e-76	248.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
ALEKFNDC_01681	585394.RHOM_07855	2.74e-139	395.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
ALEKFNDC_01682	585394.RHOM_07860	0.0	973.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
ALEKFNDC_01683	585394.RHOM_07865	5.04e-278	761.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
ALEKFNDC_01684	585394.RHOM_07870	3.78e-126	362.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ALEKFNDC_01685	585394.RHOM_07875	0.0	923.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia	186801|Clostridia	E	Belongs to the alpha-IPM synthase homocitrate synthase family	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
ALEKFNDC_01688	585394.RHOM_07895	4.71e-51	163.0	2EJ0U@1|root,33CS0@2|Bacteria,1VKD6@1239|Firmicutes,24W6Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01689	622312.ROSEINA2194_03829	2.17e-35	122.0	2BC9Q@1|root,325UU@2|Bacteria,1URUY@1239|Firmicutes,24WWT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01690	585394.RHOM_07905	1.44e-213	601.0	COG3391@1|root,COG5492@1|root,COG3391@2|Bacteria,COG5492@2|Bacteria,1TR9I@1239|Firmicutes,24CXQ@186801|Clostridia	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
ALEKFNDC_01691	585394.RHOM_07910	0.0	1262.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia	186801|Clostridia	J	elongation factor g	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
ALEKFNDC_01692	585394.RHOM_07915	6.31e-188	530.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia	186801|Clostridia	E	prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
ALEKFNDC_01694	1235802.C823_03043	1.25e-151	437.0	COG4637@1|root,COG4637@2|Bacteria	2|Bacteria	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,AAA_15,AAA_21,PDDEXK_9
ALEKFNDC_01695	469596.HMPREF9488_02248	8.03e-33	139.0	COG4625@1|root,COG5184@1|root,COG4625@2|Bacteria,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_5,DUF11,PATR,SLH,SWM_repeat
ALEKFNDC_01696	397288.C806_04417	2.38e-153	451.0	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia,27M01@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ALEKFNDC_01697	411489.CLOL250_00372	4.18e-234	649.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,36HCI@31979|Clostridiaceae	186801|Clostridia	T	Signal transduction histidine kinase	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_01698	411474.COPEUT_01943	8.25e-138	392.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_01699	1256908.HMPREF0373_00304	1.7e-187	524.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,25V01@186806|Eubacteriaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
ALEKFNDC_01700	411461.DORFOR_03149	2.25e-99	301.0	COG0526@1|root,COG0526@2|Bacteria,1UY9A@1239|Firmicutes,24C03@186801|Clostridia,27WII@189330|Dorea	186801|Clostridia	M	COG COG0526 Thiol-disulfide isomerase and THIoredoxins	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
ALEKFNDC_01701	585394.RHOM_13440	1.08e-159	453.0	28KEH@1|root,2ZA0R@2|Bacteria,1V76J@1239|Firmicutes,24JHU@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4300
ALEKFNDC_01702	622312.ROSEINA2194_02781	6.08e-57	182.0	2EF5Q@1|root,338YV@2|Bacteria,1VJS5@1239|Firmicutes,24RWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01703	585394.RHOM_06380	1.35e-160	454.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
ALEKFNDC_01704	585394.RHOM_06375	5.92e-102	296.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
ALEKFNDC_01705	2325.TKV_c09470	1.65e-25	106.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,42GYT@68295|Thermoanaerobacterales	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
ALEKFNDC_01706	585394.RHOM_06365	2.45e-36	127.0	COG2198@1|root,COG2198@2|Bacteria,1VGD4@1239|Firmicutes,25CZI@186801|Clostridia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
ALEKFNDC_01707	585394.RHOM_06360	6.22e-270	773.0	COG2199@1|root,COG2200@1|root,COG2200@2|Bacteria,COG3706@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
ALEKFNDC_01708	642492.Clole_1639	3.03e-303	852.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_01709	357809.Cphy_0218	0.0	1189.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,21YQ6@1506553|Lachnoclostridium	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,Gal_mutarotas_2,Glyco_hydro_31
ALEKFNDC_01710	1195236.CTER_3491	3.33e-184	533.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V4UB@1239|Firmicutes,24BJM@186801|Clostridia,3WRKI@541000|Ruminococcaceae	186801|Clostridia	K	PFAM response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
ALEKFNDC_01711	1469948.JPNB01000001_gene966	0.0	889.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E82@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01712	1469948.JPNB01000001_gene965	1.58e-309	857.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36DEY@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01713	180332.JTGN01000001_gene4817	2.8e-98	297.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V2EN@1239|Firmicutes,24GG9@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
ALEKFNDC_01714	585501.HMPREF6123_1295	6.4e-56	186.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,24BKQ@186801|Clostridia,2PRAW@265975|Oribacterium	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
ALEKFNDC_01716	1476876.JOJO01000010_gene2886	4.01e-16	90.5	COG2304@1|root,COG2304@2|Bacteria,2GKPD@201174|Actinobacteria	201174|Actinobacteria	E	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
ALEKFNDC_01717	665950.HMPREF1025_00892	3.11e-123	364.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,27IYF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_01719	585394.RHOM_09595	1.06e-261	727.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
ALEKFNDC_01720	622312.ROSEINA2194_00129	4e-44	142.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia	186801|Clostridia	J	50S ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
ALEKFNDC_01721	585394.RHOM_09585	2.55e-153	439.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia	186801|Clostridia	J	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
ALEKFNDC_01722	585394.RHOM_09580	2.4e-158	448.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
ALEKFNDC_01723	622312.ROSEINA2194_00134	4.54e-228	631.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
ALEKFNDC_01726	622312.ROSEINA2194_01355	4.48e-307	842.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4,HTH_24
ALEKFNDC_01727	622312.ROSEINA2194_03508	0.0	1065.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia	186801|Clostridia	J	Glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
ALEKFNDC_01728	585394.RHOM_05560	6.64e-147	420.0	COG1655@1|root,COG1655@2|Bacteria,1V2CM@1239|Firmicutes,25CK4@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2225)	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	DUF2225
ALEKFNDC_01729	585394.RHOM_05565	1.39e-228	643.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia	186801|Clostridia	K	aminotransferase class I and II	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
ALEKFNDC_01730	1226325.HMPREF1548_00426	3.54e-89	268.0	28PR6@1|root,2ZCD4@2|Bacteria,1VRUS@1239|Firmicutes,25DRA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01731	658086.HMPREF0994_04643	3.16e-298	825.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27RMB@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
ALEKFNDC_01732	658086.HMPREF0994_04642	2.43e-164	467.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27QSG@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
ALEKFNDC_01733	658086.HMPREF0994_04641	3.95e-151	435.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,27JBD@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ALEKFNDC_01734	658086.HMPREF0994_04640	5.81e-189	529.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27MDB@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ALEKFNDC_01735	1226325.HMPREF1548_00432	9.32e-152	433.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
ALEKFNDC_01736	585394.RHOM_05575	6.14e-298	812.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia	186801|Clostridia	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
ALEKFNDC_01737	622312.ROSEINA2194_04241	4.55e-243	669.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ALEKFNDC_01738	585394.RHOM_05585	1.94e-86	258.0	COG0454@1|root,COG0456@2|Bacteria,1V4GU@1239|Firmicutes,24IME@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	RimI	-	2.3.1.1	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10
ALEKFNDC_01739	622312.ROSEINA2194_03939	4.13e-249	689.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
ALEKFNDC_01740	585394.RHOM_05595	1.95e-195	544.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
ALEKFNDC_01741	585394.RHOM_05600	3.02e-246	681.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
ALEKFNDC_01742	585394.RHOM_05605	1.06e-142	417.0	COG2182@1|root,COG2182@2|Bacteria,1V0VV@1239|Firmicutes,24E7F@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_01743	622312.ROSEINA2194_03945	5.28e-51	171.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia	186801|Clostridia	L	TIGRFAM Competence protein ComEA, helix-hairpin-helix	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
ALEKFNDC_01744	585394.RHOM_05615	2.59e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_01745	585394.RHOM_05620	1.29e-273	757.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_01746	585394.RHOM_05625	1.23e-162	463.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
ALEKFNDC_01747	585394.RHOM_05630	6.44e-179	542.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia	186801|Clostridia	M	Competence protein ComEC	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
ALEKFNDC_01748	622312.ROSEINA2194_03952	1.39e-186	524.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia	186801|Clostridia	L	DNA polymerase III (delta' subunit)	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
ALEKFNDC_01749	585394.RHOM_05640	1.11e-41	138.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
ALEKFNDC_01750	585394.RHOM_05645	8.27e-176	499.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
ALEKFNDC_01751	585394.RHOM_05650	6.82e-168	486.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia	186801|Clostridia	M	stage II sporulation protein P	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
ALEKFNDC_01752	585394.RHOM_05655	4.76e-77	235.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
ALEKFNDC_01753	622312.ROSEINA2194_03960	0.0	902.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia	186801|Clostridia	E	Asparagine synthase, glutamine-hydrolyzing	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
ALEKFNDC_01754	483218.BACPEC_02584	2.82e-59	184.0	COG3668@1|root,COG3668@2|Bacteria,1V9NW@1239|Firmicutes,24KYQ@186801|Clostridia,2697W@186813|unclassified Clostridiales	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
ALEKFNDC_01755	585394.RHOM_05085	4.26e-251	690.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
ALEKFNDC_01756	585394.RHOM_05090	1.43e-43	142.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes	1239|Firmicutes	S	sporulation protein, YlmC YmxH family	ylmC	-	-	-	-	-	-	-	-	-	-	-	PRC
ALEKFNDC_01757	585394.RHOM_05095	7.84e-101	292.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
ALEKFNDC_01758	585394.RHOM_05100	1.49e-31	115.0	2E9G7@1|root,333PE@2|Bacteria,1VHIP@1239|Firmicutes,24UC4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01759	585394.RHOM_05105	1.47e-100	293.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia	186801|Clostridia	F	HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
ALEKFNDC_01760	585394.RHOM_05110	1.21e-94	276.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia	186801|Clostridia	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
ALEKFNDC_01761	622312.ROSEINA2194_01540	5.61e-127	361.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
ALEKFNDC_01762	585394.RHOM_13045	7.12e-276	776.0	COG1609@1|root,COG2199@1|root,COG1609@2|Bacteria,COG3706@2|Bacteria,1TSMK@1239|Firmicutes,24EJV@186801|Clostridia	186801|Clostridia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
ALEKFNDC_01763	1235790.C805_02517	3.25e-151	464.0	COG4188@1|root,COG4188@2|Bacteria,1UGK7@1239|Firmicutes,24CXP@186801|Clostridia	186801|Clostridia	S	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
ALEKFNDC_01764	1235802.C823_03877	5.72e-184	526.0	COG2866@1|root,COG3409@1|root,COG2866@2|Bacteria,COG3409@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,25WZ3@186806|Eubacteriaceae	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	LysM,PG_binding_1,Peptidase_M14
ALEKFNDC_01765	411469.EUBHAL_02917	8.24e-144	414.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,25VJT@186806|Eubacteriaceae	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
ALEKFNDC_01766	585394.RHOM_09385	1.69e-76	246.0	2DMDS@1|root,32QT4@2|Bacteria,1UINH@1239|Firmicutes,25EP3@186801|Clostridia	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
ALEKFNDC_01767	622312.ROSEINA2194_00480	8.01e-203	574.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
ALEKFNDC_01768	1414720.CBYM010000014_gene2732	1.78e-316	903.0	COG3250@1|root,COG3250@2|Bacteria,1TU92@1239|Firmicutes,248WD@186801|Clostridia,36FQK@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_01769	1211844.CBLM010000119_gene3415	4.31e-18	82.8	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,3VQ2Q@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
ALEKFNDC_01770	1121335.Clst_1077	7.32e-254	735.0	COG2182@1|root,COG2182@2|Bacteria,1UJPM@1239|Firmicutes,25F7T@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_01771	1121335.Clst_1077	1.46e-119	371.0	COG2182@1|root,COG2182@2|Bacteria,1UJPM@1239|Firmicutes,25F7T@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_01772	1449050.JNLE01000003_gene2908	1.28e-157	450.0	COG1175@1|root,COG1175@2|Bacteria,1TR0M@1239|Firmicutes,24CRB@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_01773	585394.RHOM_09245	1.72e-112	323.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
ALEKFNDC_01775	585394.RHOM_09240	2.92e-45	148.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
ALEKFNDC_01776	585394.RHOM_09230	5.85e-87	261.0	2C6U1@1|root,30XIE@2|Bacteria,1V4EP@1239|Firmicutes,24J3E@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
ALEKFNDC_01779	585394.RHOM_09220	1.05e-93	274.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
ALEKFNDC_01780	622312.ROSEINA2194_01247	3.2e-196	547.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia	186801|Clostridia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
ALEKFNDC_01781	622312.ROSEINA2194_01246	4.57e-60	191.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
ALEKFNDC_01782	585394.RHOM_09205	0.0	1048.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
ALEKFNDC_01783	585394.RHOM_09200	0.0	937.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
ALEKFNDC_01784	585394.RHOM_09195	1.71e-198	553.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
ALEKFNDC_01785	585394.RHOM_09190	9.41e-192	547.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
ALEKFNDC_01786	585394.RHOM_09185	4.55e-203	569.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
ALEKFNDC_01787	585394.RHOM_09180	7.63e-120	348.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
ALEKFNDC_01788	585394.RHOM_09175	1.55e-231	643.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
ALEKFNDC_01789	742740.HMPREF9474_03791	1.47e-11	70.9	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,21YX0@1506553|Lachnoclostridium	186801|Clostridia	M	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
ALEKFNDC_01790	585394.RHOM_09165	1.1e-128	370.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
ALEKFNDC_01791	622312.ROSEINA2194_01235	0.0	907.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia	186801|Clostridia	J	exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
ALEKFNDC_01792	585394.RHOM_09155	1.38e-131	378.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
ALEKFNDC_01794	585394.RHOM_09140	6.68e-155	440.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ALEKFNDC_01796	585394.RHOM_04785	9.41e-75	225.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01797	622312.ROSEINA2194_03436	0.0	1234.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
ALEKFNDC_01798	622312.ROSEINA2194_03438	2.2e-22	108.0	COG5184@1|root,COG5184@2|Bacteria,1VDTD@1239|Firmicutes,25FD2@186801|Clostridia	186801|Clostridia	DZ	Cadherin-like beta sandwich domain	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
ALEKFNDC_01799	585394.RHOM_04750	1.41e-161	458.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
ALEKFNDC_01800	585394.RHOM_04745	9.24e-258	711.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ALEKFNDC_01801	585394.RHOM_04740	1.93e-195	545.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
ALEKFNDC_01802	585394.RHOM_04735	4.16e-110	322.0	2B3FQ@1|root,31W4P@2|Bacteria,1V6XF@1239|Firmicutes,24KDR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01803	585394.RHOM_04730	3.49e-272	750.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia	186801|Clostridia	I	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
ALEKFNDC_01806	622312.ROSEINA2194_03381	5.37e-289	790.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
ALEKFNDC_01807	1235790.C805_00793	1.8e-36	125.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,25XSB@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
ALEKFNDC_01808	585394.RHOM_11730	0.0	1072.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
ALEKFNDC_01809	585394.RHOM_11735	1.77e-314	858.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia	186801|Clostridia	C	Radical SAM	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
ALEKFNDC_01810	1256908.HMPREF0373_02435	7.28e-20	80.9	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,25XQV@186806|Eubacteriaceae	186801|Clostridia	S	Six-cysteine peptide SCIFF	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
ALEKFNDC_01811	476272.RUMHYD_00772	4.26e-267	739.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
ALEKFNDC_01812	585394.RHOM_11745	3.9e-41	140.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
ALEKFNDC_01813	585394.RHOM_11750	2.25e-161	457.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia	186801|Clostridia	G	Aldose 1-epimerase	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
ALEKFNDC_01814	1469948.JPNB01000002_gene2779	1.89e-113	330.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36HYG@31979|Clostridiaceae	186801|Clostridia	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
ALEKFNDC_01815	585394.RHOM_11755	2.46e-62	202.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia	186801|Clostridia	J	Asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
ALEKFNDC_01816	742735.HMPREF9467_00252	2.07e-252	717.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,21Z5X@1506553|Lachnoclostridium	186801|Clostridia	G	Glycosyl hydrolase family 36 C-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
ALEKFNDC_01817	1235793.C809_00094	9.24e-172	486.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,27IAP@186928|unclassified Lachnospiraceae	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
ALEKFNDC_01818	622312.ROSEINA2194_04348	1.72e-38	140.0	COG3187@1|root,COG3187@2|Bacteria,1UMA9@1239|Firmicutes,25GDD@186801|Clostridia	186801|Clostridia	O	Heat shock protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01819	585394.RHOM_16625	0.0	1115.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia	186801|Clostridia	T	domain protein	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
ALEKFNDC_01820	585394.RHOM_16620	1.11e-87	259.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
ALEKFNDC_01821	585394.RHOM_16615	6.97e-301	823.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
ALEKFNDC_01822	585394.RHOM_16105	2.97e-79	244.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
ALEKFNDC_01824	742722.HMPREF9463_01777	4.22e-18	79.3	COG1669@1|root,COG1669@2|Bacteria,2HVIG@201174|Actinobacteria,4CWW6@84998|Coriobacteriia	84998|Coriobacteriia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
ALEKFNDC_01825	622312.ROSEINA2194_00870	9.62e-305	833.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,2499K@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
ALEKFNDC_01826	585394.RHOM_16100	3.41e-18	76.6	COG2768@1|root,COG2768@2|Bacteria,1VET2@1239|Firmicutes,24QUH@186801|Clostridia	186801|Clostridia	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
ALEKFNDC_01827	585394.RHOM_16095	2.45e-212	590.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
ALEKFNDC_01828	622312.ROSEINA2194_04354	2.56e-209	583.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia	186801|Clostridia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
ALEKFNDC_01829	622312.ROSEINA2194_04355	7.86e-80	240.0	COG0394@1|root,COG0394@2|Bacteria,1UIG5@1239|Firmicutes,25EMJ@186801|Clostridia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
ALEKFNDC_01830	585394.RHOM_16080	1.24e-144	408.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
ALEKFNDC_01831	585394.RHOM_16075	1.87e-102	297.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia	186801|Clostridia	F	cytidine and deoxycytidylate deaminase zinc-binding region	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
ALEKFNDC_01832	622312.ROSEINA2194_04359	9.24e-33	115.0	2EC2U@1|root,3361T@2|Bacteria,1VK1M@1239|Firmicutes,24RW0@186801|Clostridia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
ALEKFNDC_01833	622312.ROSEINA2194_04360	1.34e-68	210.0	2CFN0@1|root,32RUQ@2|Bacteria,1VD5D@1239|Firmicutes,24MN1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_I
ALEKFNDC_01834	585394.RHOM_16055	8.22e-154	435.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ALEKFNDC_01835	1235802.C823_01323	1.62e-44	145.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,25XKI@186806|Eubacteriaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
ALEKFNDC_01836	585394.RHOM_16045	3.03e-44	151.0	COG0711@1|root,COG0711@2|Bacteria,1V74H@1239|Firmicutes,25CRV@186801|Clostridia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ALEKFNDC_01837	622312.ROSEINA2194_04364	5.73e-101	296.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24MSA@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ALEKFNDC_01838	622312.ROSEINA2194_04365	0.0	928.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
ALEKFNDC_01839	585394.RHOM_16030	1.41e-159	452.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
ALEKFNDC_01840	585394.RHOM_08430	5.21e-178	508.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
ALEKFNDC_01841	585394.RHOM_08435	2.58e-109	317.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
ALEKFNDC_01842	585394.RHOM_08440	7.14e-141	402.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
ALEKFNDC_01843	585394.RHOM_08445	3.25e-182	518.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
ALEKFNDC_01844	585394.RHOM_08450	1.02e-276	767.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
ALEKFNDC_01845	585394.RHOM_08455	1.42e-150	432.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
ALEKFNDC_01846	585394.RHOM_07130	9.28e-294	810.0	COG0589@1|root,COG0589@2|Bacteria,1TPUI@1239|Firmicutes,24826@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1538
ALEKFNDC_01847	585394.RHOM_07125	9.89e-109	319.0	COG0347@1|root,COG0347@2|Bacteria,1V65X@1239|Firmicutes,24HQ8@186801|Clostridia	186801|Clostridia	E	Belongs to the P(II) protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01848	585394.RHOM_08460	8.04e-303	838.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ALEKFNDC_01849	585394.RHOM_08460	2.85e-156	457.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
ALEKFNDC_01850	585394.RHOM_08465	3.3e-48	154.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
ALEKFNDC_01851	585394.RHOM_08470	5.9e-165	476.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UBS0@1239|Firmicutes,25B2D@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
ALEKFNDC_01852	585394.RHOM_08475	4.72e-171	483.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
ALEKFNDC_01853	622312.ROSEINA2194_00453	3.99e-155	443.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
ALEKFNDC_01854	585394.RHOM_08485	1.11e-166	473.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia	186801|Clostridia	J	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
ALEKFNDC_01855	622312.ROSEINA2194_00455	5.93e-66	202.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
ALEKFNDC_01856	585394.RHOM_08495	0.0	1237.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
ALEKFNDC_01857	585394.RHOM_08500	1.52e-51	164.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia	186801|Clostridia	J	ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
ALEKFNDC_01858	585394.RHOM_08505	1.74e-49	158.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia	186801|Clostridia	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
ALEKFNDC_01859	585394.RHOM_08510	3.76e-230	640.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
ALEKFNDC_01860	1410633.JHWR01000016_gene1040	1.13e-84	252.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,27M62@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
ALEKFNDC_01861	1321778.HMPREF1982_03317	4.08e-243	673.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,26AE5@186813|unclassified Clostridiales	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
ALEKFNDC_01862	1341157.RF007C_08915	3.57e-87	263.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
ALEKFNDC_01863	1321778.HMPREF1982_03315	5.57e-159	457.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,26A16@186813|unclassified Clostridiales	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
ALEKFNDC_01864	877424.ATWC01000015_gene635	3.8e-266	771.0	COG0642@1|root,COG0784@1|root,COG1307@1|root,COG0784@2|Bacteria,COG1307@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DegV,HATPase_c,HisKA,Hpt,Response_reg
ALEKFNDC_01865	877424.ATWC01000015_gene634	1.22e-201	606.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,27ISK@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,GAF_2,HATPase_c,HisKA,Hpt,Response_reg
ALEKFNDC_01866	877424.ATWC01000015_gene633	9.78e-133	389.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,27IRU@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
ALEKFNDC_01867	585394.RHOM_13850	1.79e-203	572.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
ALEKFNDC_01868	585394.RHOM_13855	3.19e-95	282.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
ALEKFNDC_01869	1341157.RF007C_10565	1.93e-173	489.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ALEKFNDC_01870	1298920.KI911353_gene3328	2.19e-265	732.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,21XFB@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	MET17	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
ALEKFNDC_01871	622312.ROSEINA2194_03130	2e-92	271.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia	186801|Clostridia	C	assembly protein, NifU family	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
ALEKFNDC_01872	622312.ROSEINA2194_03131	5.63e-245	677.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ALEKFNDC_01874	180332.JTGN01000006_gene3154	5.14e-173	496.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
ALEKFNDC_01876	180332.JTGN01000003_gene1793	3.69e-82	253.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
ALEKFNDC_01877	515622.bpr_I1351	3.56e-52	167.0	COG0375@1|root,COG0375@2|Bacteria,1VABW@1239|Firmicutes,24NES@186801|Clostridia,4BZG4@830|Butyrivibrio	186801|Clostridia	S	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
ALEKFNDC_01878	665956.HMPREF1032_02341	0.0	1466.0	COG0493@1|root,COG1143@1|root,COG4231@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,COG4231@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WHYH@541000|Ruminococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_9,Pyr_redox_2,Pyr_redox_3
ALEKFNDC_01879	515622.bpr_I1350	2.66e-126	363.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,4BXWJ@830|Butyrivibrio	186801|Clostridia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
ALEKFNDC_01881	641112.ACOK01000114_gene2305	5.36e-80	240.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
ALEKFNDC_01882	518637.EUBIFOR_02026	3.97e-77	231.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,3VTCC@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01883	585501.HMPREF6123_1167	6.94e-118	341.0	28KQ0@1|root,2ZA7Z@2|Bacteria,1V4X7@1239|Firmicutes,24E87@186801|Clostridia,2PTNA@265975|Oribacterium	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
ALEKFNDC_01885	411489.CLOL250_02048	1.52e-18	100.0	COG3209@1|root,COG3210@1|root,COG3209@2|Bacteria,COG3210@2|Bacteria,1W1CQ@1239|Firmicutes,24Q72@186801|Clostridia,36NF6@31979|Clostridiaceae	186801|Clostridia	M	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01886	585394.RHOM_04645	1.09e-213	610.0	COG0726@1|root,COG0860@1|root,COG0726@2|Bacteria,COG0860@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
ALEKFNDC_01887	585394.RHOM_04640	8.66e-216	605.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
ALEKFNDC_01888	585394.RHOM_04635	0.0	1140.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
ALEKFNDC_01889	642492.Clole_2676	0.0	1188.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
ALEKFNDC_01890	642492.Clole_2677	8.03e-316	888.0	COG4447@1|root,COG4447@2|Bacteria,1VJ96@1239|Firmicutes	1239|Firmicutes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01891	411462.DORLON_00274	4.94e-186	528.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,27VSU@189330|Dorea	186801|Clostridia	H	ATPase of the PP-loop superfamily implicated in cell cycle control	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
ALEKFNDC_01892	622312.ROSEINA2194_04128	4.65e-55	184.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ALEKFNDC_01893	585394.RHOM_10060	3.06e-167	479.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
ALEKFNDC_01894	585394.RHOM_04845	3.53e-63	199.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,24JBS@186801|Clostridia	186801|Clostridia	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
ALEKFNDC_01895	585394.RHOM_04850	0.0	1157.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01896	585394.RHOM_04855	0.0	989.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_01897	585394.RHOM_04860	6.43e-63	197.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
ALEKFNDC_01898	585394.RHOM_04865	0.0	1325.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia	186801|Clostridia	F	Ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
ALEKFNDC_01899	1121296.JONJ01000004_gene974	3.73e-50	162.0	COG5496@1|root,COG5496@2|Bacteria,1VAZJ@1239|Firmicutes,24MWR@186801|Clostridia,222ZV@1506553|Lachnoclostridium	186801|Clostridia	S	Thioesterase superfamily	-	-	3.1.2.29	ko:K18700	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
ALEKFNDC_01900	357809.Cphy_0713	9.01e-137	392.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,21Y17@1506553|Lachnoclostridium	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
ALEKFNDC_01901	585394.RHOM_05995	3.28e-61	189.0	2F3F9@1|root,33W92@2|Bacteria,1VVFD@1239|Firmicutes,25130@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01902	585394.RHOM_06000	7.1e-82	253.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
ALEKFNDC_01903	622312.ROSEINA2194_01565	8.5e-97	287.0	COG0328@1|root,COG3341@1|root,COG0328@2|Bacteria,COG3341@2|Bacteria,1V442@1239|Firmicutes,24HSE@186801|Clostridia	186801|Clostridia	L	Ribonuclease HI	rnhA	-	3.1.26.4	ko:K03469,ko:K06993	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	Cauli_VI,RNase_H
ALEKFNDC_01904	585394.RHOM_06010	2.26e-198	557.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
ALEKFNDC_01905	622312.ROSEINA2194_02626	1.73e-85	255.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia	186801|Clostridia	O	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
ALEKFNDC_01907	585394.RHOM_04880	3.44e-114	345.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	-	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
ALEKFNDC_01909	585394.RHOM_04900	1.39e-105	311.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia	186801|Clostridia	M	n-acetylmuramoyl-l-alanine amidase	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
ALEKFNDC_01910	585394.RHOM_04905	4.11e-191	549.0	COG0116@1|root,COG0116@2|Bacteria,1TT5F@1239|Firmicutes,249VY@186801|Clostridia	186801|Clostridia	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,UPF0020
ALEKFNDC_01911	585394.RHOM_04910	0.0	1227.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
ALEKFNDC_01914	877420.ATVW01000017_gene1701	2.65e-139	408.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,27IYG@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
ALEKFNDC_01915	1235793.C809_02443	5.79e-50	167.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,27M8T@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
ALEKFNDC_01916	1120746.CCNL01000008_gene545	3.67e-105	311.0	COG0368@1|root,COG0368@2|Bacteria	2|Bacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
ALEKFNDC_01917	537007.BLAHAN_05799	8.85e-29	108.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
ALEKFNDC_01918	1120746.CCNL01000008_gene547	2.12e-71	223.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	cobC	-	3.1.3.73,6.3.1.10	ko:K02226,ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R04594,R06529,R07302,R11173	RC00017,RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
ALEKFNDC_01919	622312.ROSEINA2194_01858	2.27e-140	407.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
ALEKFNDC_01920	689781.AUJX01000003_gene2930	3.8e-80	241.0	COG3467@1|root,COG3467@2|Bacteria,1V6NS@1239|Firmicutes,24JA3@186801|Clostridia,2PSHU@265975|Oribacterium	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	nimA	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
ALEKFNDC_01921	622312.ROSEINA2194_02722	7.14e-30	111.0	2EKR7@1|root,33EEZ@2|Bacteria,1VQ0F@1239|Firmicutes,24UDN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01922	585394.RHOM_08610	4.43e-69	214.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
ALEKFNDC_01923	585394.RHOM_08605	3.74e-158	457.0	COG4641@1|root,COG4641@2|Bacteria,1V642@1239|Firmicutes,24IV8@186801|Clostridia	186801|Clostridia	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ALEKFNDC_01924	622312.ROSEINA2194_02720	1.54e-127	366.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
ALEKFNDC_01925	585394.RHOM_08595	2.25e-305	836.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia	186801|Clostridia	E	argininosuccinate lyase	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
ALEKFNDC_01926	585394.RHOM_08590	2.31e-258	708.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
ALEKFNDC_01927	585394.RHOM_08585	4.27e-233	652.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
ALEKFNDC_01928	585394.RHOM_08580	0.0	2012.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
ALEKFNDC_01929	622312.ROSEINA2194_01352	2.5e-146	414.0	COG1207@1|root,COG1207@2|Bacteria	2|Bacteria	M	glucosamine-1-phosphate N-acetyltransferase activity	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
ALEKFNDC_01930	622312.ROSEINA2194_01774	1.73e-151	448.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ALEKFNDC_01931	585394.RHOM_08565	1.17e-121	372.0	COG1033@1|root,COG1033@2|Bacteria,1VIN4@1239|Firmicutes	1239|Firmicutes	S	YARHG	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
ALEKFNDC_01932	585394.RHOM_10150	0.0	1033.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia	186801|Clostridia	S	Abc transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
ALEKFNDC_01933	411468.CLOSCI_03722	5.29e-182	516.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,21Y5G@1506553|Lachnoclostridium	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
ALEKFNDC_01934	622312.ROSEINA2194_02760	5.87e-140	403.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
ALEKFNDC_01936	1235793.C809_01000	2.66e-38	140.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,27I99@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
ALEKFNDC_01937	397287.C807_03011	1.43e-60	204.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,27I99@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
ALEKFNDC_01938	585394.RHOM_07290	0.0	1193.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ALEKFNDC_01939	622312.ROSEINA2194_03605	2.51e-37	131.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_01940	1139219.I569_00581	4.09e-59	199.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,4HA00@91061|Bacilli,4AZ8X@81852|Enterococcaceae	91061|Bacilli	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
ALEKFNDC_01942	457412.RSAG_00813	4.47e-121	358.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3WHJ0@541000|Ruminococcaceae	186801|Clostridia	M	NlpC P60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
ALEKFNDC_01943	908340.HMPREF9406_0793	8.01e-145	452.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,36FMM@31979|Clostridiaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01944	1158601.I585_00435	0.0	984.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,4HBZY@91061|Bacilli,4B0FA@81852|Enterococcaceae	91061|Bacilli	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
ALEKFNDC_01945	658659.HMPREF0983_03979	2.96e-38	132.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,3VQEW@526524|Erysipelotrichia	1239|Firmicutes	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
ALEKFNDC_01947	1449338.JQLU01000005_gene2736	4.45e-152	442.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,4HCHD@91061|Bacilli	91061|Bacilli	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Omega_Repress,Rep_trans
ALEKFNDC_01948	641107.CDLVIII_5765	8.28e-101	300.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,36E89@31979|Clostridiaceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K10010	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3.10,3.A.1.3.14	-	-	ABC_tran
ALEKFNDC_01949	411474.COPEUT_01236	4e-298	891.0	COG4124@1|root,COG4733@1|root,COG4124@2|Bacteria,COG4733@2|Bacteria,1TSXQ@1239|Firmicutes,24CRT@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 26 family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM27,CBM_11,CW_binding_1,Glyco_hydro_26,Gram_pos_anchor,SLH
ALEKFNDC_01950	622312.ROSEINA2194_00571	0.0	1208.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_01951	397291.C804_03759	0.0	1058.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_01952	658086.HMPREF0994_01674	3.48e-66	218.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V41T@1239|Firmicutes,25B4Q@186801|Clostridia,27TZT@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
ALEKFNDC_01953	585394.RHOM_14655	1.05e-77	233.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
ALEKFNDC_01954	585394.RHOM_14660	0.0	871.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ALEKFNDC_01955	585394.RHOM_14665	6.19e-175	492.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
ALEKFNDC_01956	622312.ROSEINA2194_02211	0.0	875.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
ALEKFNDC_01957	622312.ROSEINA2194_02212	4.68e-62	196.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
ALEKFNDC_01958	411463.EUBVEN_02695	2.89e-61	194.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,25X82@186806|Eubacteriaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
ALEKFNDC_01959	585394.RHOM_14685	8.34e-38	127.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
ALEKFNDC_01960	411463.EUBVEN_02693	9.3e-139	396.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,25VMP@186806|Eubacteriaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
ALEKFNDC_01961	33035.JPJF01000016_gene4083	1.94e-63	201.0	2DIV4@1|root,30473@2|Bacteria,1V5EC@1239|Firmicutes,24IZE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01964	622312.ROSEINA2194_03463	0.0	882.0	COG0175@1|root,COG1149@1|root,COG5270@1|root,COG0175@2|Bacteria,COG1149@2|Bacteria,COG5270@2|Bacteria,1TSMI@1239|Firmicutes,24A18@186801|Clostridia	186801|Clostridia	EH	Phosphoadenosine phosphosulfate reductase	-	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_7,PAPS_reduct
ALEKFNDC_01965	622312.ROSEINA2194_03462	1.7e-118	348.0	28MTH@1|root,2ZB1P@2|Bacteria,1UYJE@1239|Firmicutes,24D9M@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF4007)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4007
ALEKFNDC_01966	622312.ROSEINA2194_03461	0.0	1221.0	COG0262@1|root,COG0262@2|Bacteria,1UIN4@1239|Firmicutes,25ENR@186801|Clostridia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01967	622312.ROSEINA2194_03460	6.37e-167	479.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia	186801|Clostridia	E	Cysteine desulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
ALEKFNDC_01968	97139.C824_00955	2.14e-284	803.0	COG1479@1|root,COG3472@1|root,COG1479@2|Bacteria,COG3472@2|Bacteria,1U5K1@1239|Firmicutes,24A01@186801|Clostridia,36I99@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF262
ALEKFNDC_01970	1235790.C805_02971	5.14e-33	126.0	COG0419@1|root,COG0419@2|Bacteria,1TTBF@1239|Firmicutes,24CKY@186801|Clostridia,25XC7@186806|Eubacteriaceae	186801|Clostridia	L	AAA domain	-	-	-	ko:K19171	-	-	-	-	ko00000,ko02048	-	-	-	AAA_23
ALEKFNDC_01971	622312.ROSEINA2194_03457	2.34e-268	756.0	COG0419@1|root,COG0419@2|Bacteria,1TTBF@1239|Firmicutes,24CKY@186801|Clostridia	186801|Clostridia	L	DNA sulfur modification protein DndD	-	-	-	ko:K19171	-	-	-	-	ko00000,ko02048	-	-	-	AAA_23
ALEKFNDC_01972	1235790.C805_02970	1.6e-76	233.0	2E30B@1|root,32SUY@2|Bacteria,1UPTA@1239|Firmicutes,24T23@186801|Clostridia,25YY1@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01973	622312.ROSEINA2194_03455	0.0	1512.0	COG3513@1|root,COG3513@2|Bacteria,1TPSD@1239|Firmicutes,249YY@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer	cas9	-	-	ko:K09952	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH_4
ALEKFNDC_01974	622312.ROSEINA2194_03454	1.25e-176	496.0	COG1518@1|root,COG1518@2|Bacteria,1TT0J@1239|Firmicutes,24CB1@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
ALEKFNDC_01975	622312.ROSEINA2194_03453	4.91e-56	176.0	COG3512@1|root,COG3512@2|Bacteria,1VEH4@1239|Firmicutes,24N00@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
ALEKFNDC_01977	622312.ROSEINA2194_03155	6.02e-105	310.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
ALEKFNDC_01978	622312.ROSEINA2194_03156	7.17e-235	647.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia	186801|Clostridia	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
ALEKFNDC_01979	585394.RHOM_02890	1.75e-74	229.0	2CB94@1|root,32XMH@2|Bacteria,1VCD1@1239|Firmicutes,24MX5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01980	622312.ROSEINA2194_03158	2.82e-189	529.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
ALEKFNDC_01981	585394.RHOM_02880	1.53e-25	96.7	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01982	622312.ROSEINA2194_03159	1.17e-70	216.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
ALEKFNDC_01983	622312.ROSEINA2194_03160	2.12e-128	369.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
ALEKFNDC_01984	622312.ROSEINA2194_03161	1.32e-90	266.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia	186801|Clostridia	K	Hydrolase, P-loop family	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
ALEKFNDC_01985	622312.ROSEINA2194_03162	2.43e-65	204.0	2AZ5D@1|root,31RC2@2|Bacteria,1V74Z@1239|Firmicutes,24KGW@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
ALEKFNDC_01986	622312.ROSEINA2194_00823	1.66e-113	329.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
ALEKFNDC_01987	622312.ROSEINA2194_00824	0.0	1251.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
ALEKFNDC_01988	585394.RHOM_02840	2.23e-33	119.0	2EGCD@1|root,33A46@2|Bacteria,1VMG3@1239|Firmicutes,24UKI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_01989	585394.RHOM_02835	3.63e-42	144.0	2DNZJ@1|root,32ZX7@2|Bacteria,1VHMI@1239|Firmicutes,24SBG@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
ALEKFNDC_01990	585394.RHOM_02825	4.27e-76	238.0	COG5523@1|root,COG5523@2|Bacteria,1VB3B@1239|Firmicutes,24N6Q@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
ALEKFNDC_01991	585394.RHOM_02820	4.11e-296	813.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia	186801|Clostridia	F	permease	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
ALEKFNDC_01992	585394.RHOM_02815	3.86e-79	244.0	COG4758@1|root,COG4758@2|Bacteria,1V7WJ@1239|Firmicutes,24A1Z@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154
ALEKFNDC_01993	397291.C804_03441	3.29e-72	221.0	COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,24G1R@186801|Clostridia,27MWM@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
ALEKFNDC_01994	585394.RHOM_02805	8.84e-169	475.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
ALEKFNDC_01995	585394.RHOM_02800	4.88e-213	594.0	COG0182@1|root,COG0182@2|Bacteria,1TPDK@1239|Firmicutes,249C5@186801|Clostridia	186801|Clostridia	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
ALEKFNDC_01997	1469948.JPNB01000002_gene3250	1.67e-197	557.0	COG1680@1|root,COG1680@2|Bacteria,1UC2C@1239|Firmicutes,24B3Q@186801|Clostridia,36FP4@31979|Clostridiaceae	186801|Clostridia	V	beta-lactamase	-	-	3.4.16.4	ko:K21469	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Beta-lactamase
ALEKFNDC_01998	1280694.AUJQ01000011_gene1768	5.24e-132	390.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3NGIB@46205|Pseudobutyrivibrio	186801|Clostridia	J	tRNA synthetases class II (A)	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
ALEKFNDC_01999	622312.ROSEINA2194_02126	9.69e-42	142.0	2FC79@1|root,344B3@2|Bacteria,1W1AZ@1239|Firmicutes,24W3X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02000	33035.JPJF01000089_gene114	3.65e-101	318.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
ALEKFNDC_02001	1226325.HMPREF1548_02292	1.37e-237	680.0	COG3534@1|root,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,CBM_4_9,Cadherin-like,Laminin_G_3
ALEKFNDC_02002	1298920.KI911353_gene1794	3.25e-76	261.0	COG2972@1|root,COG2972@2|Bacteria,1VS0D@1239|Firmicutes,24YHS@186801|Clostridia,221U8@1506553|Lachnoclostridium	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
ALEKFNDC_02003	697281.Mahau_2735	2.39e-43	169.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TV2J@1239|Firmicutes,249HW@186801|Clostridia,42J1B@68295|Thermoanaerobacterales	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
ALEKFNDC_02004	1298920.KI911353_gene1795	3.66e-171	496.0	COG1653@1|root,COG1653@2|Bacteria,1V5R7@1239|Firmicutes,25BSW@186801|Clostridia,221PP@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
ALEKFNDC_02005	610130.Closa_1668	1.23e-135	394.0	COG1175@1|root,COG1175@2|Bacteria,1V0JI@1239|Firmicutes,25C5R@186801|Clostridia,2200H@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
ALEKFNDC_02006	1298920.KI911353_gene1797	3.04e-134	389.0	COG0395@1|root,COG0395@2|Bacteria,1V2Q1@1239|Firmicutes,24A8E@186801|Clostridia,2202Q@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ALEKFNDC_02008	1274374.CBLK010000070_gene1204	3.35e-233	696.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,4HB2V@91061|Bacilli,26SFU@186822|Paenibacillaceae	1239|Firmicutes	G	Alpha-mannosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
ALEKFNDC_02009	658086.HMPREF0994_06533	0.0	962.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,27IHI@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_02010	1226325.HMPREF1548_05939	6.25e-36	122.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,36MP8@31979|Clostridiaceae	186801|Clostridia	P	Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
ALEKFNDC_02011	585394.RHOM_03450	7.15e-43	140.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
ALEKFNDC_02012	585394.RHOM_03455	0.0	1236.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
ALEKFNDC_02013	1235799.C818_03332	7.94e-17	72.4	2C6KI@1|root,33J10@2|Bacteria,1VKBK@1239|Firmicutes,24UUY@186801|Clostridia,27Q8P@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
ALEKFNDC_02016	585394.RHOM_11845	6.42e-103	302.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24JSE@186801|Clostridia	186801|Clostridia	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
ALEKFNDC_02017	622312.ROSEINA2194_02179	4.42e-32	118.0	2E5D8@1|root,33058@2|Bacteria,1VERG@1239|Firmicutes,24S0M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1344
ALEKFNDC_02018	658086.HMPREF0994_04050	1.89e-115	355.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,27KFI@186928|unclassified Lachnospiraceae	186801|Clostridia	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
ALEKFNDC_02019	585394.RHOM_03840	3.86e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ALEKFNDC_02021	585394.RHOM_04185	8.76e-131	374.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
ALEKFNDC_02022	585394.RHOM_04190	5.46e-62	195.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
ALEKFNDC_02023	1122919.KB905551_gene1678	1.34e-35	128.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,4HE13@91061|Bacilli,26SJ5@186822|Paenibacillaceae	91061|Bacilli	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ALEKFNDC_02024	1410630.JNKP01000001_gene1787	3.49e-74	231.0	COG0726@1|root,COG0726@2|Bacteria,1U0B6@1239|Firmicutes,24895@186801|Clostridia,27M6G@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
ALEKFNDC_02025	1235792.C808_04909	1.12e-53	171.0	COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,25CMS@186801|Clostridia,27U60@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
ALEKFNDC_02026	1235790.C805_02487	1.15e-69	218.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,25ZEW@186806|Eubacteriaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
ALEKFNDC_02027	585394.RHOM_11510	9.28e-67	206.0	COG0597@1|root,COG0597@2|Bacteria,1VFDG@1239|Firmicutes,24PUH@186801|Clostridia	186801|Clostridia	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
ALEKFNDC_02028	585394.RHOM_11515	3.34e-57	183.0	COG0671@1|root,COG0671@2|Bacteria,1VB2R@1239|Firmicutes,24MQ9@186801|Clostridia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
ALEKFNDC_02029	585394.RHOM_03350	1.29e-214	615.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
ALEKFNDC_02030	622312.ROSEINA2194_02243	4.75e-167	472.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
ALEKFNDC_02031	585394.RHOM_03995	0.0	1377.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
ALEKFNDC_02032	1280696.ATVY01000023_gene798	6.99e-05	45.4	29155@1|root,2ZNSF@2|Bacteria,1W51U@1239|Firmicutes,257BM@186801|Clostridia,4C0H7@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02033	411463.EUBVEN_02650	9.3e-46	156.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,25VUS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02034	411489.CLOL250_02471	9.88e-34	124.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,36ES0@31979|Clostridiaceae	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02035	592026.GCWU0000282_001791	4.59e-59	189.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
ALEKFNDC_02036	1235798.C817_04466	1.18e-43	145.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,27VT5@189330|Dorea	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
ALEKFNDC_02037	457412.RSAG_02065	1.62e-34	141.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,25DEX@186801|Clostridia,3WSGH@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
ALEKFNDC_02038	585394.RHOM_04795	5.27e-61	195.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
ALEKFNDC_02039	1262449.CP6013_1068	1.05e-34	121.0	COG1733@1|root,COG1733@2|Bacteria,1V707@1239|Firmicutes,24HCZ@186801|Clostridia,36IYB@31979|Clostridiaceae	186801|Clostridia	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
ALEKFNDC_02040	397291.C804_05930	1.22e-142	413.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,27U55@186928|unclassified Lachnospiraceae	186801|Clostridia	P	FecCD transport family	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
ALEKFNDC_02041	397291.C804_05931	6.49e-112	330.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,27MTD@186928|unclassified Lachnospiraceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
ALEKFNDC_02042	1469948.JPNB01000001_gene1957	6.41e-57	181.0	COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,24HGF@186801|Clostridia,36IXW@31979|Clostridiaceae	186801|Clostridia	O	Belongs to the glutathione peroxidase family	-	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
ALEKFNDC_02043	585394.RHOM_14885	6.18e-37	130.0	COG1669@1|root,COG1669@2|Bacteria,1VBYU@1239|Firmicutes,24N0Y@186801|Clostridia	186801|Clostridia	S	TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
ALEKFNDC_02044	397291.C804_04092	3.58e-163	475.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,27TN6@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15755	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
ALEKFNDC_02045	397291.C804_05932	1.75e-130	384.0	COG0614@1|root,COG0614@2|Bacteria,1UIJ9@1239|Firmicutes,25BH2@186801|Clostridia	186801|Clostridia	P	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
ALEKFNDC_02046	585394.RHOM_14100	2.22e-124	358.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia	186801|Clostridia	S	Proton-coupled thiamine transporter YuaJ	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
ALEKFNDC_02047	622312.ROSEINA2194_03984	7.51e-195	543.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
ALEKFNDC_02048	622312.ROSEINA2194_03986	0.0	964.0	COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,248A4@186801|Clostridia	186801|Clostridia	M	penicillin-binding protein 1A	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
ALEKFNDC_02049	622312.ROSEINA2194_03988	1.05e-138	420.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
ALEKFNDC_02050	622312.ROSEINA2194_03989	1.65e-167	478.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia	186801|Clostridia	L	Ser Thr phosphatase family protein	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
ALEKFNDC_02051	622312.ROSEINA2194_03990	2.21e-102	299.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia	186801|Clostridia	K	stage V sporulation protein T	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
ALEKFNDC_02052	658086.HMPREF0994_03950	9.76e-211	608.0	COG3525@1|root,COG3525@2|Bacteria,1TSXM@1239|Firmicutes,248U1@186801|Clostridia,27QES@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
ALEKFNDC_02053	478749.BRYFOR_07839	1.73e-68	234.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_02054	622312.ROSEINA2194_04229	7.41e-91	276.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
ALEKFNDC_02055	585394.RHOM_11680	1.52e-120	344.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
ALEKFNDC_02056	585394.RHOM_11675	7.58e-121	355.0	29TA1@1|root,30EH1@2|Bacteria,1V43N@1239|Firmicutes,24IGU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02058	585394.RHOM_11420	1.43e-177	509.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
ALEKFNDC_02059	622312.ROSEINA2194_02225	3.51e-81	251.0	COG4862@1|root,COG4862@2|Bacteria	2|Bacteria	NOT	establishment of competence for transformation	mecA	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
ALEKFNDC_02062	1235790.C805_01468	2.68e-74	238.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
ALEKFNDC_02063	397288.C806_01355	8.88e-255	722.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,27KFU@186928|unclassified Lachnospiraceae	186801|Clostridia	U	V-type ATPase 116kDa subunit family	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
ALEKFNDC_02064	397290.C810_03102	7.44e-57	180.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,27MUF@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
ALEKFNDC_02065	397288.C806_01357	2.68e-49	158.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,27NKU@186928|unclassified Lachnospiraceae	186801|Clostridia	C	ATP synthase (F/14-kDa) subunit	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
ALEKFNDC_02066	357809.Cphy_3443	1.99e-21	94.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,21Z0G@1506553|Lachnoclostridium	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
ALEKFNDC_02067	397288.C806_01359	0.0	928.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,27IS3@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
ALEKFNDC_02068	1235790.C805_01474	6.86e-273	753.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,25VDA@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
ALEKFNDC_02069	1235790.C805_01475	1.76e-103	304.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,25WFD@186806|Eubacteriaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
ALEKFNDC_02070	1235800.C819_00237	3.94e-173	496.0	COG3434@1|root,COG3434@2|Bacteria,1TPWC@1239|Firmicutes,248M1@186801|Clostridia,27J37@186928|unclassified Lachnospiraceae	186801|Clostridia	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
ALEKFNDC_02071	622312.ROSEINA2194_02683	3.27e-292	805.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
ALEKFNDC_02072	1408323.JQKK01000005_gene154	2.7e-42	144.0	29PCB@1|root,30AAJ@2|Bacteria,1V4H2@1239|Firmicutes,24IF4@186801|Clostridia,27M51@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02073	1121335.Clst_1079	4.95e-64	203.0	COG0395@1|root,COG0395@2|Bacteria,1TRS1@1239|Firmicutes,24ARW@186801|Clostridia,3WH53@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ALEKFNDC_02074	1094508.Tsac_1160	1.06e-173	504.0	COG3391@1|root,COG3391@2|Bacteria,1U3IC@1239|Firmicutes,2490J@186801|Clostridia,42I05@68295|Thermoanaerobacterales	186801|Clostridia	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,Yip1
ALEKFNDC_02075	1121335.Clst_1081	1.54e-67	213.0	COG2881@1|root,COG2881@2|Bacteria,1VBWZ@1239|Firmicutes,24MD2@186801|Clostridia	186801|Clostridia	S	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
ALEKFNDC_02076	1121335.Clst_1082	6.39e-279	801.0	COG3420@1|root,COG3420@2|Bacteria,1TSNZ@1239|Firmicutes,24D4T@186801|Clostridia,3WHC4@541000|Ruminococcaceae	186801|Clostridia	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02077	357809.Cphy_2268	1.27e-25	104.0	COG1175@1|root,COG1175@2|Bacteria,1U73Q@1239|Firmicutes,24AFP@186801|Clostridia	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ALEKFNDC_02078	1121335.Clst_1083	1.58e-63	204.0	COG1175@1|root,COG1175@2|Bacteria,1U73Q@1239|Firmicutes,24AFP@186801|Clostridia,3WHI4@541000|Ruminococcaceae	186801|Clostridia	G	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
ALEKFNDC_02079	1121335.Clst_1084	1.88e-130	381.0	COG0395@1|root,COG0395@2|Bacteria,1UYH5@1239|Firmicutes,24AMA@186801|Clostridia,3WH39@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_02080	1094508.Tsac_1165	1.37e-128	389.0	COG1653@1|root,COG1653@2|Bacteria,1TXES@1239|Firmicutes,25JZ6@186801|Clostridia,42INH@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	-
ALEKFNDC_02081	357809.Cphy_3376	1.45e-41	147.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,21YZW@1506553|Lachnoclostridium	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
ALEKFNDC_02082	1449050.JNLE01000003_gene2847	1.66e-101	309.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,36HMC@31979|Clostridiaceae	186801|Clostridia	K	PFAM Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_02083	397291.C804_03195	8.81e-225	622.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia,27JZU@186928|unclassified Lachnospiraceae	186801|Clostridia	G	beta-1,4-mannooligosaccharide phosphorylase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_02084	357809.Cphy_2058	1.01e-155	456.0	COG2730@1|root,COG2730@2|Bacteria,1UVAD@1239|Firmicutes,25KF9@186801|Clostridia,223EG@1506553|Lachnoclostridium	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
ALEKFNDC_02085	1123075.AUDP01000048_gene1544	8.82e-57	194.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02086	585394.RHOM_05925	7.03e-244	683.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
ALEKFNDC_02087	515620.EUBELI_00163	5.69e-279	771.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,25URI@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
ALEKFNDC_02088	411490.ANACAC_02200	0.0	1130.0	COG0480@1|root,COG3688@1|root,COG0480@2|Bacteria,COG3688@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia	186801|Clostridia	J	Elongation factor	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
ALEKFNDC_02090	1226325.HMPREF1548_03838	8.84e-06	44.7	2BEGM@1|root,3287Y@2|Bacteria,1UU58@1239|Firmicutes,255IQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02091	1226325.HMPREF1548_02366	3.31e-123	355.0	COG2964@1|root,COG2964@2|Bacteria,1V33R@1239|Firmicutes,25CHI@186801|Clostridia,36WW5@31979|Clostridiaceae	186801|Clostridia	S	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
ALEKFNDC_02092	658086.HMPREF0994_00211	4.79e-63	195.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,27N9W@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
ALEKFNDC_02093	658086.HMPREF0994_00210	0.0	897.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,27TF9@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Na+/H+ antiporter family	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
ALEKFNDC_02094	1226325.HMPREF1548_02362	8.29e-232	644.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,36DKQ@31979|Clostridiaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_02095	1235793.C809_02152	2.51e-204	572.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,27TF6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
ALEKFNDC_02096	585394.RHOM_05960	4.36e-223	629.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia	186801|Clostridia	J	NOL1 NOP2 sun family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
ALEKFNDC_02097	515620.EUBELI_20221	4.61e-100	307.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1TRCK@1239|Firmicutes,24A7A@186801|Clostridia,25XIB@186806|Eubacteriaceae	186801|Clostridia	T	CHASE	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF,PAS_3,dCache_1
ALEKFNDC_02098	397288.C806_00497	1.75e-43	157.0	COG2199@1|root,COG3452@1|root,COG2199@2|Bacteria,COG3452@2|Bacteria,1V037@1239|Firmicutes,24YFW@186801|Clostridia,27IDA@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,SBP_bac_3
ALEKFNDC_02099	397287.C807_02411	7.26e-84	253.0	COG4720@1|root,COG4720@2|Bacteria,1V5I7@1239|Firmicutes,25CJU@186801|Clostridia,27U5H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:DUF3816	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
ALEKFNDC_02100	556261.HMPREF0240_03527	0.0	919.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia,36PCY@31979|Clostridiaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
ALEKFNDC_02101	397291.C804_04805	4.58e-209	591.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02102	622312.ROSEINA2194_04371	1.69e-171	483.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
ALEKFNDC_02103	657322.FPR_14500	4.2e-149	427.0	COG0582@1|root,COG0582@2|Bacteria,1TT1I@1239|Firmicutes,24C80@186801|Clostridia,3WI9D@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
ALEKFNDC_02104	585394.RHOM_02025	4.35e-18	81.6	2FJSC@1|root,34BF3@2|Bacteria,1VZYZ@1239|Firmicutes,2549D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02105	702450.CUW_0318	3.91e-17	79.7	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,3VTTK@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_02106	1230342.CTM_05143	2.98e-22	95.1	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,24IYG@186801|Clostridia,36GVF@31979|Clostridiaceae	186801|Clostridia	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
ALEKFNDC_02107	1536774.H70357_11880	8.61e-28	110.0	COG3315@1|root,COG3315@2|Bacteria,1TSGJ@1239|Firmicutes,4HCZS@91061|Bacilli,26V7A@186822|Paenibacillaceae	91061|Bacilli	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
ALEKFNDC_02108	1226325.HMPREF1548_05583	0.0	1424.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,36G82@31979|Clostridiaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
ALEKFNDC_02109	1235798.C817_05228	6.81e-117	350.0	COG0662@1|root,COG2169@1|root,COG0662@2|Bacteria,COG2169@2|Bacteria,1V9CR@1239|Firmicutes,24K6B@186801|Clostridia,27WPH@189330|Dorea	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
ALEKFNDC_02110	622312.ROSEINA2194_04066	1.29e-69	237.0	COG0840@1|root,COG0840@2|Bacteria,1V0JG@1239|Firmicutes,24A5M@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ALEKFNDC_02111	1449050.JNLE01000003_gene675	5.71e-75	234.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,36KUT@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
ALEKFNDC_02112	1541959.KQ51_01201	5.61e-99	298.0	COG3290@1|root,COG3290@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K11614	ko02020,map02020	M00490	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c_5,PAS_9,SPOB_a
ALEKFNDC_02113	1449050.JNLE01000003_gene677	6.7e-173	512.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
ALEKFNDC_02114	1449050.JNLE01000003_gene678	2.77e-190	555.0	COG1132@1|root,COG1132@2|Bacteria,1TPZP@1239|Firmicutes,249WV@186801|Clostridia,36EX9@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
ALEKFNDC_02115	585394.RHOM_15670	5.18e-93	274.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
ALEKFNDC_02116	622312.ROSEINA2194_00784	3.06e-54	177.0	2ECHQ@1|root,336FZ@2|Bacteria,1VI4C@1239|Firmicutes,24TFT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02117	622312.ROSEINA2194_00783	9.58e-204	567.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia	186801|Clostridia	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
ALEKFNDC_02118	585394.RHOM_15685	3.89e-170	477.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia	186801|Clostridia	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
ALEKFNDC_02119	585394.RHOM_15690	2.39e-60	187.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02120	622312.ROSEINA2194_00780	1.27e-174	493.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
ALEKFNDC_02121	585394.RHOM_15700	7.31e-222	613.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
ALEKFNDC_02122	622312.ROSEINA2194_00777	1.13e-127	375.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
ALEKFNDC_02123	585394.RHOM_14185	1.09e-117	348.0	COG0392@1|root,COG0392@2|Bacteria,1V2TI@1239|Firmicutes,24K1U@186801|Clostridia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
ALEKFNDC_02124	622312.ROSEINA2194_04045	0.0	916.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
ALEKFNDC_02125	585394.RHOM_14195	7.43e-149	428.0	COG0770@1|root,COG0770@2|Bacteria,1TS8M@1239|Firmicutes,24CJW@186801|Clostridia	186801|Clostridia	M	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
ALEKFNDC_02126	585394.RHOM_14200	5.37e-186	521.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ALEKFNDC_02127	585394.RHOM_14205	4.33e-154	438.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia	186801|Clostridia	S	Phospholipase, patatin family	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
ALEKFNDC_02128	622312.ROSEINA2194_04052	1.76e-61	193.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
ALEKFNDC_02129	585394.RHOM_14215	1.08e-53	180.0	2DU28@1|root,33NME@2|Bacteria,1VMV6@1239|Firmicutes,24V3C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02130	585394.RHOM_14220	1.96e-194	546.0	COG1619@1|root,COG1619@2|Bacteria,1TZSN@1239|Firmicutes,25CIH@186801|Clostridia	186801|Clostridia	V	proteins homologs of microcin C7 resistance protein MccF	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S66
ALEKFNDC_02133	585394.RHOM_05920	3.92e-137	409.0	COG1132@1|root,COG1132@2|Bacteria,1UHQP@1239|Firmicutes,25E4H@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	cydC	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02134	397290.C810_02249	1.73e-35	122.0	COG5577@1|root,COG5577@2|Bacteria,1TU9X@1239|Firmicutes,25IH5@186801|Clostridia,27S9B@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
ALEKFNDC_02135	397290.C810_02248	5.99e-21	84.0	29VDD@1|root,325Y2@2|Bacteria,1UHHD@1239|Firmicutes,25JIV@186801|Clostridia,27SCF@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02136	585394.RHOM_05970	1.52e-213	609.0	COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG5002@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
ALEKFNDC_02137	1163671.JAGI01000002_gene2184	7.17e-54	184.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,36DIN@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the TtcA family	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
ALEKFNDC_02138	585394.RHOM_04810	4.47e-64	207.0	COG3773@1|root,COG3773@2|Bacteria,1VHG1@1239|Firmicutes,24SYE@186801|Clostridia	186801|Clostridia	M	COG3773 Cell wall hydrolyses involved in spore germination	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2
ALEKFNDC_02140	585394.RHOM_08970	4.02e-39	131.0	COG2158@1|root,COG2158@2|Bacteria	2|Bacteria	S	Cysteine-rich small domain	cbiA	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
ALEKFNDC_02141	1120746.CCNL01000008_gene565	8e-96	287.0	COG2243@1|root,COG2243@2|Bacteria	2|Bacteria	H	precorrin-2 c20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151,4.99.1.3	ko:K02190,ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05807,R05808	RC00003,RC01012,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
ALEKFNDC_02142	397291.C804_03012	3.31e-181	522.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,27IYT@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
ALEKFNDC_02143	1120746.CCNL01000008_gene555	1.31e-237	682.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	cobK	-	1.3.1.106,1.3.1.54,1.3.1.76,2.1.1.131,2.1.1.132,2.1.1.196,2.1.1.289,3.7.1.12,4.99.1.4	ko:K00595,ko:K02191,ko:K02304,ko:K03399,ko:K05895,ko:K05934,ko:K13541	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947,R05149,R05150,R05180,R05809,R05812,R05813,R07772,R07774,R07775	RC00003,RC01012,RC01034,RC01279,RC01280,RC01293,RC01545,RC02052,RC02053,RC02054,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15725	CbiJ,Methyltransf_31,TP_methylase
ALEKFNDC_02144	1120746.CCNL01000008_gene554	1.91e-84	254.0	COG1010@1|root,COG1010@2|Bacteria	2|Bacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10	ko:K02232,ko:K05934,ko:K05936,ko:K13541	ko00860,ko01100,map00860,map01100	M00122	R05180,R05181,R05225,R05809,R05810,R07772	RC00003,RC00010,RC01293,RC01294,RC01302,RC01545,RC02049,RC02097,RC03471	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiC,TP_methylase
ALEKFNDC_02145	483218.BACPEC_02670	1.91e-18	83.2	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,2680F@186813|unclassified Clostridiales	186801|Clostridia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
ALEKFNDC_02147	1469948.JPNB01000001_gene2323	1.53e-56	196.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,36DM5@31979|Clostridiaceae	186801|Clostridia	H	Cobalamin biosynthesis protein cbiG	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
ALEKFNDC_02148	622312.ROSEINA2194_01854	3.25e-135	388.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia	186801|Clostridia	H	precorrin-4 C(11)-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
ALEKFNDC_02149	622312.ROSEINA2194_01855	3.89e-167	480.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
ALEKFNDC_02150	585394.RHOM_09030	1.96e-224	639.0	COG0079@1|root,COG2082@1|root,COG0079@2|Bacteria,COG2082@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ALEKFNDC_02151	397288.C806_01857	2.46e-29	132.0	COG3209@1|root,COG3209@2|Bacteria,1UJWP@1239|Firmicutes,25FCF@186801|Clostridia,27T8Y@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
ALEKFNDC_02153	585394.RHOM_03735	2.29e-293	800.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
ALEKFNDC_02154	585394.RHOM_06140	2.47e-307	878.0	28J8A@1|root,2Z93H@2|Bacteria,1UYEZ@1239|Firmicutes,24AV4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02155	411469.EUBHAL_02516	4.24e-178	504.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia,25WEJ@186806|Eubacteriaceae	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
ALEKFNDC_02156	585394.RHOM_06135	0.0	1197.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
ALEKFNDC_02157	1235792.C808_00459	7.87e-202	568.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,27IBJ@186928|unclassified Lachnospiraceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
ALEKFNDC_02158	585394.RHOM_04685	4.39e-212	597.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia	186801|Clostridia	S	Hydrogenase maturation GTPase HydF	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
ALEKFNDC_02159	585394.RHOM_04680	0.0	892.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia	186801|Clostridia	C	biosynthesis protein ThiH	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
ALEKFNDC_02160	585394.RHOM_04675	3.95e-193	543.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia	186801|Clostridia	C	Iron-only hydrogenase maturation rSAM protein HydE	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
ALEKFNDC_02161	585394.RHOM_04670	5.81e-42	138.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia	186801|Clostridia	K	Iron-only hydrogenase system regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02162	585394.RHOM_04830	0.0	1104.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
ALEKFNDC_02163	585394.RHOM_04825	0.0	1025.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia	186801|Clostridia	S	ABC transporter	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
ALEKFNDC_02164	1449050.JNLE01000003_gene106	4.17e-12	73.9	2EG3M@1|root,339VN@2|Bacteria,1VN0Z@1239|Firmicutes,24UD6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02165	500632.CLONEX_03904	1.23e-85	259.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
ALEKFNDC_02166	622312.ROSEINA2194_04469	5.1e-201	566.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
ALEKFNDC_02167	585394.RHOM_05120	1.66e-190	544.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
ALEKFNDC_02168	483218.BACPEC_02966	5.29e-100	303.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,26A1M@186813|unclassified Clostridiales	186801|Clostridia	O	DnaJ molecular chaperone homology domain	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
ALEKFNDC_02169	1160721.RBI_I01639	5.82e-75	234.0	COG0726@1|root,COG0726@2|Bacteria,1V8XF@1239|Firmicutes,24JZT@186801|Clostridia,3WIMA@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Polysacc_deac_1
ALEKFNDC_02170	411474.COPEUT_00455	0.0	1249.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
ALEKFNDC_02171	515620.EUBELI_01734	7.25e-229	641.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,25V84@186806|Eubacteriaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02172	397291.C804_05617	2.58e-94	278.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,27M9G@186928|unclassified Lachnospiraceae	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ALEKFNDC_02174	622312.ROSEINA2194_02492	2.1e-172	484.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_02175	903814.ELI_3973	2.29e-86	264.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,25WEG@186806|Eubacteriaceae	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
ALEKFNDC_02176	622312.ROSEINA2194_01770	1.55e-65	201.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
ALEKFNDC_02177	585394.RHOM_03480	3.73e-40	133.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24R22@186801|Clostridia	186801|Clostridia	P	Heavy metal-associated domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HMA
ALEKFNDC_02178	622312.ROSEINA2194_01772	0.0	971.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
ALEKFNDC_02179	411902.CLOBOL_05591	2.48e-34	121.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2218J@1506553|Lachnoclostridium	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02180	622312.ROSEINA2194_02448	0.0	1095.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia	186801|Clostridia	P	heavy metal translocating P-type ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
ALEKFNDC_02181	622312.ROSEINA2194_02134	8.13e-37	146.0	2CB93@1|root,30P4I@2|Bacteria,1V581@1239|Firmicutes,24IR0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02182	483218.BACPEC_02952	1.9e-84	264.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,26BFC@186813|unclassified Clostridiales	186801|Clostridia	S	Serine hydrolase (FSH1)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
ALEKFNDC_02183	483218.BACPEC_02951	3.94e-126	374.0	COG2199@1|root,COG2199@2|Bacteria,1VBH6@1239|Firmicutes,24P8P@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
ALEKFNDC_02184	585394.RHOM_09350	9.36e-300	823.0	COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia	186801|Clostridia	C	Iron only hydrogenase large subunit, C-terminal domain	-	-	1.12.7.2	ko:K00533	-	-	R00019	-	ko00000,ko01000	-	-	-	Fe_hyd_lg_C,Fer4
ALEKFNDC_02185	622312.ROSEINA2194_01364	2.68e-111	328.0	COG0561@1|root,COG0561@2|Bacteria,1TSZZ@1239|Firmicutes,25B6T@186801|Clostridia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
ALEKFNDC_02186	585394.RHOM_09340	1.24e-182	518.0	COG1073@1|root,COG1073@2|Bacteria,1UF81@1239|Firmicutes,24BZ7@186801|Clostridia	186801|Clostridia	H	Protein of unknown function (DUF2974)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2974
ALEKFNDC_02187	585394.RHOM_09335	4.86e-55	172.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
ALEKFNDC_02188	1007096.BAGW01000014_gene1156	2.86e-43	156.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
ALEKFNDC_02190	1121344.JHZO01000003_gene939	1.93e-59	190.0	COG1704@1|root,COG1704@2|Bacteria,1V3Z0@1239|Firmicutes,24IH4@186801|Clostridia,3WM16@541000|Ruminococcaceae	186801|Clostridia	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
ALEKFNDC_02191	411489.CLOL250_02693	7.16e-110	346.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.41	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	-	R02111	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	AMPK1_CBM,Alpha-amylase,Big_2,Big_5,CBM_48,Flg_new,Gram_pos_anchor,PUD,SLH
ALEKFNDC_02192	622312.ROSEINA2194_00341	0.0	943.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
ALEKFNDC_02193	585394.RHOM_03640	2.3e-289	810.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia	186801|Clostridia	S	Abc transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
ALEKFNDC_02194	666681.M301_0409	3.2e-21	106.0	COG3850@1|root,COG5001@1|root,COG3850@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria,2KKKT@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
ALEKFNDC_02196	1410618.JNKI01000001_gene1495	5.84e-33	135.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1U4YK@1239|Firmicutes,4H6FE@909932|Negativicutes	909932|Negativicutes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
ALEKFNDC_02197	585394.RHOM_03645	1.84e-72	221.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
ALEKFNDC_02198	622312.ROSEINA2194_02462	3.48e-134	385.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
ALEKFNDC_02200	585394.RHOM_03660	4.41e-103	303.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia	186801|Clostridia	S	COG NOG11305 non supervised orthologous group	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
ALEKFNDC_02201	585394.RHOM_03665	2.33e-54	174.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
ALEKFNDC_02202	585394.RHOM_03670	3.09e-44	148.0	2EJW5@1|root,33DKW@2|Bacteria,1VPSK@1239|Firmicutes,24W6H@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3837)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3837
ALEKFNDC_02203	515620.EUBELI_20101	1.59e-212	587.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,25WQB@186806|Eubacteriaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
ALEKFNDC_02205	515620.EUBELI_20100	1.16e-140	397.0	COG1713@1|root,COG1713@2|Bacteria,1V2XB@1239|Firmicutes,25EFJ@186801|Clostridia,25YAB@186806|Eubacteriaceae	186801|Clostridia	H	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
ALEKFNDC_02206	397290.C810_01647	8.17e-141	397.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,24B0N@186801|Clostridia,27KYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Maltose acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2,Mac
ALEKFNDC_02207	411461.DORFOR_02251	8.94e-182	509.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,27W8Q@189330|Dorea	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02208	1280694.AUJQ01000006_gene775	1.21e-95	307.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia,3NHV9@46205|Pseudobutyrivibrio	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF,SBP_bac_3
ALEKFNDC_02209	585394.RHOM_14880	1.3e-174	498.0	COG0738@1|root,COG0738@2|Bacteria,1TPB5@1239|Firmicutes,24913@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ALEKFNDC_02210	411461.DORFOR_00452	1.92e-286	788.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,27UQI@189330|Dorea	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
ALEKFNDC_02211	411469.EUBHAL_00026	0.0	978.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,25UY4@186806|Eubacteriaceae	186801|Clostridia	L	ATP-dependent DNA helicase RecQ	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
ALEKFNDC_02212	457412.RSAG_01452	3.46e-244	680.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02213	411462.DORLON_01191	5.73e-116	342.0	COG0583@1|root,COG0583@2|Bacteria,1UXFR@1239|Firmicutes,25C6Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K21755	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02214	416870.llmg_1857	5.74e-11	61.2	COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli	91061|Bacilli	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_02215	585394.RHOM_16605	0.0	1352.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia	186801|Clostridia	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,DUF4968,UvrD-helicase,UvrD_C,UvrD_C_2
ALEKFNDC_02216	1506994.JNLQ01000001_gene263	2.16e-144	413.0	COG2013@1|root,COG2013@2|Bacteria,1TP7N@1239|Firmicutes,249B4@186801|Clostridia,4BZ30@830|Butyrivibrio	186801|Clostridia	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
ALEKFNDC_02217	478749.BRYFOR_09858	7.86e-41	138.0	296XG@1|root,2ZU65@2|Bacteria,1V0MN@1239|Firmicutes,24GI1@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
ALEKFNDC_02218	658655.HMPREF0988_01416	4.73e-72	219.0	2AUVQ@1|root,31KJ2@2|Bacteria,1V1UV@1239|Firmicutes,24H4A@186801|Clostridia,27MKJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02219	1336241.JAEB01000004_gene516	2.97e-38	132.0	2AUVQ@1|root,2ZI4I@2|Bacteria,1V1YP@1239|Firmicutes,24FSR@186801|Clostridia,25W7C@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02220	585394.RHOM_09980	3.28e-128	367.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
ALEKFNDC_02221	585394.RHOM_09985	4.31e-162	459.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
ALEKFNDC_02222	585394.RHOM_09990	7.26e-285	803.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia	186801|Clostridia	KLT	serine threonine protein kinase	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
ALEKFNDC_02223	622312.ROSEINA2194_03525	2.75e-126	365.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia	186801|Clostridia	T	Phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
ALEKFNDC_02224	622312.ROSEINA2194_03526	1.26e-211	589.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
ALEKFNDC_02225	622312.ROSEINA2194_03527	1.14e-201	572.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
ALEKFNDC_02226	622312.ROSEINA2194_03528	1.22e-142	405.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
ALEKFNDC_02227	585394.RHOM_10015	5.63e-178	501.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
ALEKFNDC_02228	622312.ROSEINA2194_03530	6.49e-92	271.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ALEKFNDC_02229	585394.RHOM_10025	0.0	1027.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
ALEKFNDC_02230	585394.RHOM_10030	4.5e-219	622.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
ALEKFNDC_02231	585394.RHOM_10035	3.04e-65	201.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
ALEKFNDC_02232	585394.RHOM_10045	1.34e-200	557.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
ALEKFNDC_02233	585394.RHOM_10050	5.15e-90	265.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia	186801|Clostridia	F	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
ALEKFNDC_02234	622312.ROSEINA2194_03538	2.51e-119	344.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia	186801|Clostridia	O	DnaJ domain protein	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
ALEKFNDC_02235	585394.RHOM_04700	4.76e-185	530.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia	186801|Clostridia	E	amino acid carrier protein	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
ALEKFNDC_02236	411462.DORLON_00099	9.08e-202	564.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
ALEKFNDC_02237	1410632.JHWW01000013_gene237	8.08e-13	68.9	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,27NJZ@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
ALEKFNDC_02238	411474.COPEUT_00629	7.17e-22	95.9	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
ALEKFNDC_02239	411459.RUMOBE_02708	1.92e-97	296.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_02240	140626.JHWB01000022_gene2045	3.02e-107	316.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
ALEKFNDC_02242	1408306.JHXX01000003_gene1412	3.45e-74	225.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,4BXFH@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
ALEKFNDC_02243	1414720.CBYM010000020_gene2482	1.41e-165	483.0	COG0657@1|root,COG0657@2|Bacteria,1USHI@1239|Firmicutes,24DIN@186801|Clostridia,36IKW@31979|Clostridiaceae	186801|Clostridia	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02244	1280680.AUJU01000023_gene2540	5.01e-117	357.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,4C1ND@830|Butyrivibrio	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
ALEKFNDC_02245	1410616.JHXE01000014_gene390	5.39e-139	402.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,24KGS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02246	742738.HMPREF9460_00250	6.22e-14	70.1	arCOG04966@1|root,33EHA@2|Bacteria,1VN4X@1239|Firmicutes,24VEA@186801|Clostridia,26C56@186813|unclassified Clostridiales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02247	742733.HMPREF9469_01638	1.88e-63	201.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,220IG@1506553|Lachnoclostridium	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
ALEKFNDC_02248	445973.CLOBAR_00478	2.5e-268	744.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,25RRQ@186804|Peptostreptococcaceae	186801|Clostridia	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
ALEKFNDC_02251	1235798.C817_04780	7.06e-07	55.5	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,27WZS@189330|Dorea	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
ALEKFNDC_02252	742765.HMPREF9457_02012	3.27e-83	247.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia	186801|Clostridia	S	Replication initiator protein A	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
ALEKFNDC_02253	742765.HMPREF9457_02013	7.15e-75	224.0	296J0@1|root,347SA@2|Bacteria,1VZKB@1239|Firmicutes,252U1@186801|Clostridia,27WQ9@189330|Dorea	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
ALEKFNDC_02254	1235802.C823_03008	1.01e-91	293.0	COG0840@1|root,COG1145@1|root,COG4624@1|root,COG0840@2|Bacteria,COG1145@2|Bacteria,COG4624@2|Bacteria,1TSVR@1239|Firmicutes,248TC@186801|Clostridia,25VKU@186806|Eubacteriaceae	186801|Clostridia	CNT	Iron only hydrogenase large subunit, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,Fer4_10,Fer4_7,MCPsignal
ALEKFNDC_02255	483218.BACPEC_02992	1.99e-101	320.0	COG0840@1|root,COG0840@2|Bacteria,1TSW1@1239|Firmicutes,24B19@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ALEKFNDC_02256	585394.RHOM_08020	3.18e-127	369.0	28NT4@1|root,2ZBRW@2|Bacteria,1UXVI@1239|Firmicutes,24ABY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02257	622312.ROSEINA2194_03854	2.51e-310	852.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia	186801|Clostridia	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
ALEKFNDC_02258	585394.RHOM_08005	9.02e-104	311.0	COG1406@1|root,COG1406@2|Bacteria,1V46M@1239|Firmicutes,24B3C@186801|Clostridia	186801|Clostridia	N	Chemotaxis phosphatase CheX	-	-	-	-	-	-	-	-	-	-	-	-	CheX
ALEKFNDC_02259	585394.RHOM_08000	2.11e-59	186.0	COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
ALEKFNDC_02260	622312.ROSEINA2194_03851	3.6e-43	144.0	2EH8T@1|root,33B0N@2|Bacteria,1VKIJ@1239|Firmicutes,24V3Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02261	585394.RHOM_07990	7.78e-140	397.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07775	ko02020,map02020	M00458	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_02262	585394.RHOM_07985	1.93e-233	659.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,24P7E@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_02263	622312.ROSEINA2194_03850	1.63e-286	787.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ALEKFNDC_02264	585394.RHOM_07975	1.03e-68	210.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
ALEKFNDC_02265	585394.RHOM_14090	1.42e-179	508.0	COG3287@1|root,COG3287@2|Bacteria,1UK57@1239|Firmicutes,24D5K@186801|Clostridia	186801|Clostridia	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
ALEKFNDC_02266	585394.RHOM_14095	1.7e-71	231.0	COG0840@1|root,COG0840@2|Bacteria,1TY0J@1239|Firmicutes,24DGH@186801|Clostridia	186801|Clostridia	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
ALEKFNDC_02267	411474.COPEUT_01787	2.66e-282	779.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
ALEKFNDC_02268	585394.RHOM_05195	4.68e-271	747.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
ALEKFNDC_02269	622312.ROSEINA2194_03091	0.0	899.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia	186801|Clostridia	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
ALEKFNDC_02270	622312.ROSEINA2194_00711	1.25e-262	721.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia	186801|Clostridia	C	alcohol dehydrogenase	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
ALEKFNDC_02271	622312.ROSEINA2194_04423	8.18e-101	295.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_02272	585394.RHOM_06020	0.0	917.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
ALEKFNDC_02273	585394.RHOM_06025	0.0	966.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
ALEKFNDC_02274	585394.RHOM_06035	8.34e-147	414.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
ALEKFNDC_02275	585394.RHOM_06040	1.04e-166	469.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
ALEKFNDC_02276	585394.RHOM_06045	2.22e-190	532.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia	186801|Clostridia	G	Transketolase	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
ALEKFNDC_02277	585394.RHOM_06050	1.63e-169	473.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
ALEKFNDC_02278	585394.RHOM_06055	1.45e-175	498.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
ALEKFNDC_02279	1121115.AXVN01000045_gene2061	3.65e-27	112.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y28B@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,dCache_1
ALEKFNDC_02280	689781.AUJX01000002_gene2998	9.44e-18	87.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,2PS4I@265975|Oribacterium	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_02281	622312.ROSEINA2194_04168	4.62e-204	577.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_02282	585394.RHOM_08335	1.03e-156	443.0	COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia	186801|Clostridia	C	electron transport complex, RnfABCDGE type, B subunit	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
ALEKFNDC_02283	585394.RHOM_08340	4.83e-123	352.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
ALEKFNDC_02284	585394.RHOM_08345	9.91e-139	395.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
ALEKFNDC_02285	585394.RHOM_08350	1.12e-26	102.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
ALEKFNDC_02286	585394.RHOM_08350	1.95e-61	194.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
ALEKFNDC_02287	585394.RHOM_08355	1.52e-185	520.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
ALEKFNDC_02288	585394.RHOM_08360	1.28e-278	766.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia	186801|Clostridia	C	Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
ALEKFNDC_02289	585394.RHOM_08365	3.6e-124	371.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
ALEKFNDC_02290	585394.RHOM_08370	5.93e-166	466.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia	186801|Clostridia	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
ALEKFNDC_02291	585394.RHOM_08375	1.19e-240	664.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia	186801|Clostridia	J	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
ALEKFNDC_02292	585394.RHOM_08380	1.55e-151	432.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia	186801|Clostridia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
ALEKFNDC_02293	585394.RHOM_08385	3.02e-128	367.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
ALEKFNDC_02294	622312.ROSEINA2194_00502	2.98e-222	622.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
ALEKFNDC_02295	585394.RHOM_08395	8.75e-193	538.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
ALEKFNDC_02296	1235793.C809_02550	0.0	945.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27IE8@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02297	585394.RHOM_14450	9.26e-109	315.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia	186801|Clostridia	J	ribosomal protein l17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
ALEKFNDC_02298	1069534.LRC_05120	5.88e-87	259.0	COG4283@1|root,COG4283@2|Bacteria,1V8M5@1239|Firmicutes,4HHMT@91061|Bacilli,3F6RT@33958|Lactobacillaceae	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
ALEKFNDC_02299	1408311.JNJM01000002_gene1192	1.34e-76	229.0	29A02@1|root,2ZX1N@2|Bacteria,1V48B@1239|Firmicutes,24HF1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02300	658655.HMPREF0988_00617	9.47e-45	146.0	COG3070@1|root,COG3070@2|Bacteria,1V42M@1239|Firmicutes,24JNV@186801|Clostridia,27NC9@186928|unclassified Lachnospiraceae	186801|Clostridia	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
ALEKFNDC_02302	585394.RHOM_01065	3.33e-274	758.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
ALEKFNDC_02303	622312.ROSEINA2194_02099	1.42e-153	432.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_02304	585394.RHOM_01075	0.0	1196.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
ALEKFNDC_02305	585394.RHOM_01080	5.04e-178	514.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia	186801|Clostridia	O	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
ALEKFNDC_02306	585394.RHOM_01085	1.8e-202	563.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia	186801|Clostridia	S	domain protein	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
ALEKFNDC_02307	585394.RHOM_01090	1.35e-272	754.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
ALEKFNDC_02309	1235798.C817_03166	8.87e-71	217.0	2CUHA@1|root,33IHG@2|Bacteria,1VPC1@1239|Firmicutes,24W2W@186801|Clostridia,27WQP@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02310	1235792.C808_02239	1.86e-20	82.4	2C7EF@1|root,33FU0@2|Bacteria,1VMPB@1239|Firmicutes,25PQ4@186801|Clostridia,27QDU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02311	1235799.C818_00006	5.26e-47	160.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,27KDS@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
ALEKFNDC_02312	1410650.JHWL01000026_gene38	1.08e-73	233.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia,4BW6J@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_02313	556261.HMPREF0240_00813	9.63e-122	361.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,248BZ@186801|Clostridia,36E93@31979|Clostridiaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_02314	1469948.JPNB01000002_gene3622	1.06e-201	573.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,36FU2@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
ALEKFNDC_02315	1469948.JPNB01000002_gene3616	0.0	1006.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,36FQM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_02316	658086.HMPREF0994_04316	3.35e-82	257.0	COG2207@1|root,COG2207@2|Bacteria,1UGXT@1239|Firmicutes,24EUQ@186801|Clostridia,27NK5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ALEKFNDC_02317	1226325.HMPREF1548_02854	2.71e-213	597.0	COG4225@1|root,COG4225@2|Bacteria,1TR4A@1239|Firmicutes,248Z1@186801|Clostridia,36F9Z@31979|Clostridiaceae	186801|Clostridia	S	Glucuronyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
ALEKFNDC_02318	585394.RHOM_04080	0.0	917.0	COG3387@1|root,COG3387@2|Bacteria,1UI0N@1239|Firmicutes,25DI4@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_N
ALEKFNDC_02319	1256908.HMPREF0373_03204	0.0	1030.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,25V6K@186806|Eubacteriaceae	186801|Clostridia	J	L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
ALEKFNDC_02320	585394.RHOM_11610	6.75e-271	744.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia	186801|Clostridia	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
ALEKFNDC_02321	585394.RHOM_03085	1.59e-100	293.0	COG3090@1|root,COG3090@2|Bacteria,1V1US@1239|Firmicutes,24G5M@186801|Clostridia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ALEKFNDC_02322	585394.RHOM_03080	8.06e-217	604.0	COG1638@1|root,COG1638@2|Bacteria,1TSSW@1239|Firmicutes,24DW9@186801|Clostridia	186801|Clostridia	G	TRAP transporter solute receptor, DctP family	-	-	-	-	-	-	-	-	-	-	-	-	DctP,TAT_signal
ALEKFNDC_02323	478749.BRYFOR_06633	1.71e-151	429.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ALEKFNDC_02324	411459.RUMOBE_02060	4.68e-63	196.0	COG1846@1|root,COG1846@2|Bacteria,1V749@1239|Firmicutes,24KYW@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ALEKFNDC_02325	483218.BACPEC_02515	7.76e-262	733.0	COG1132@1|root,COG1132@2|Bacteria,1TPTK@1239|Firmicutes,249W7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02326	515620.EUBELI_20433	1.21e-298	830.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,25URG@186806|Eubacteriaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02327	483218.BACPEC_02513	1.71e-79	239.0	COG1846@1|root,COG1846@2|Bacteria,1V8Z3@1239|Firmicutes,24I7U@186801|Clostridia,26BAN@186813|unclassified Clostridiales	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
ALEKFNDC_02328	1392493.JIAB01000001_gene729	3.38e-308	842.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,27J2Z@186928|unclassified Lachnospiraceae	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
ALEKFNDC_02329	1235802.C823_05146	1.01e-104	363.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,25V5I@186806|Eubacteriaceae	186801|Clostridia	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
ALEKFNDC_02330	585394.RHOM_07260	2.12e-72	218.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
ALEKFNDC_02331	1280688.AUJB01000008_gene1258	2.69e-35	120.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3NHEH@46205|Pseudobutyrivibrio	186801|Clostridia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
ALEKFNDC_02332	180332.JTGN01000010_gene4424	2.08e-58	203.0	COG5492@1|root,COG5492@2|Bacteria,1UINF@1239|Firmicutes,25EP2@186801|Clostridia	186801|Clostridia	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
ALEKFNDC_02333	585394.RHOM_08170	1.64e-165	467.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ALEKFNDC_02334	585394.RHOM_08175	1.65e-267	744.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
ALEKFNDC_02336	483218.BACPEC_01722	8.58e-276	775.0	COG0666@1|root,COG3507@1|root,COG0666@2|Bacteria,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,26AET@186813|unclassified Clostridiales	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Ank_2,Ank_4,Glyco_hydro_43
ALEKFNDC_02337	515622.bpr_I1585	3.37e-210	602.0	COG3507@1|root,COG3507@2|Bacteria,1UDW2@1239|Firmicutes,24A81@186801|Clostridia,4BYGR@830|Butyrivibrio	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
ALEKFNDC_02338	1280668.ATVT01000001_gene794	1.39e-93	281.0	COG2755@1|root,COG2755@2|Bacteria,1V2SC@1239|Firmicutes,24H62@186801|Clostridia,4BWRN@830|Butyrivibrio	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_02339	1298920.KI911353_gene1189	1.36e-146	419.0	COG0395@1|root,COG0395@2|Bacteria,1TSX2@1239|Firmicutes,24891@186801|Clostridia,222N7@1506553|Lachnoclostridium	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_02340	1304866.K413DRAFT_2463	7.07e-146	420.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,36GXV@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_02341	1304866.K413DRAFT_2462	1.79e-68	224.0	COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
ALEKFNDC_02342	585394.RHOM_03095	2.18e-60	191.0	2CPN3@1|root,32SJG@2|Bacteria,1VASE@1239|Firmicutes,24KG6@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
ALEKFNDC_02343	585394.RHOM_03100	1e-205	586.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
ALEKFNDC_02344	585394.RHOM_03105	1.83e-111	329.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V1DC@1239|Firmicutes,24GJV@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
ALEKFNDC_02345	585394.RHOM_03110	8.96e-162	462.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia	186801|Clostridia	G	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ALEKFNDC_02346	622312.ROSEINA2194_02021	4.96e-189	535.0	COG0738@1|root,COG0738@2|Bacteria,1UZWI@1239|Firmicutes,24H3U@186801|Clostridia	186801|Clostridia	G	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ALEKFNDC_02347	585394.RHOM_03115	1.01e-64	199.0	COG1917@1|root,COG1917@2|Bacteria,1VCF2@1239|Firmicutes,25BAE@186801|Clostridia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
ALEKFNDC_02348	1294142.CINTURNW_3431	8.98e-315	868.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,36DVT@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
ALEKFNDC_02349	1280698.AUJS01000017_gene1837	1.22e-110	331.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27W54@189330|Dorea	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
ALEKFNDC_02350	1256908.HMPREF0373_00535	1.15e-76	243.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,25WTS@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
ALEKFNDC_02351	411459.RUMOBE_00759	3.67e-46	148.0	2E3HI@1|root,32YG4@2|Bacteria,1VHJH@1239|Firmicutes,24V52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02352	411469.EUBHAL_00686	2.33e-35	120.0	2EC3Y@1|root,3362U@2|Bacteria,1VF1Z@1239|Firmicutes,24QVE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02353	622312.ROSEINA2194_00099	2.06e-38	138.0	2B7HH@1|root,320MM@2|Bacteria,1V7BY@1239|Firmicutes,24KSD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02354	1235800.C819_02309	3.39e-41	155.0	2BCEZ@1|root,3260K@2|Bacteria,1URZY@1239|Firmicutes,259XQ@186801|Clostridia,27QI3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02356	585394.RHOM_13415	1.3e-111	321.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia	186801|Clostridia	S	ThiW protein	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
ALEKFNDC_02357	471875.RUMLAC_00916	7.13e-100	290.0	COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,24HI8@186801|Clostridia,3WIP1@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
ALEKFNDC_02359	585394.RHOM_06395	2.22e-165	482.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia	186801|Clostridia	P	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
ALEKFNDC_02360	585394.RHOM_06400	2.11e-147	419.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia	186801|Clostridia	S	(AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
ALEKFNDC_02361	585394.RHOM_06405	6.83e-98	288.0	COG1309@1|root,COG1309@2|Bacteria,1V7SY@1239|Firmicutes,24JI6@186801|Clostridia	186801|Clostridia	K	transcriptional regulator TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
ALEKFNDC_02362	1235800.C819_03666	0.0	1088.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,27TNA@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_02363	585394.RHOM_06415	1.61e-289	798.0	2BZA3@1|root,2Z7YV@2|Bacteria,1TSER@1239|Firmicutes,24AF5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02364	585394.RHOM_06420	7.5e-259	717.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,247VA@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	lacS	-	-	ko:K03292,ko:K11104,ko:K16209	-	-	-	-	ko00000,ko02000	2.A.2,2.A.2.1,2.A.2.2	-	-	MFS_2
ALEKFNDC_02365	622312.ROSEINA2194_01205	0.0	1191.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
ALEKFNDC_02366	622312.ROSEINA2194_02692	2.55e-161	463.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24AFJ@186801|Clostridia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_2
ALEKFNDC_02367	622312.ROSEINA2194_02691	5.76e-270	741.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
ALEKFNDC_02368	1298920.KI911353_gene4678	4.78e-262	732.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,220H9@1506553|Lachnoclostridium	186801|Clostridia	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
ALEKFNDC_02369	1122217.KB899567_gene669	0.0	910.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4H454@909932|Negativicutes	909932|Negativicutes	G	Fibronectin type III-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_02370	622312.ROSEINA2194_02688	3.44e-169	476.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia	186801|Clostridia	P	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
ALEKFNDC_02371	622312.ROSEINA2194_02710	2.29e-152	429.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24G53@186801|Clostridia	186801|Clostridia	K	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
ALEKFNDC_02372	622312.ROSEINA2194_02711	0.0	956.0	COG4191@1|root,COG4191@2|Bacteria,1TSH9@1239|Firmicutes,24CTJ@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
ALEKFNDC_02373	622312.ROSEINA2194_02712	5.47e-282	769.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
ALEKFNDC_02374	350688.Clos_2061	1.96e-25	112.0	28NDR@1|root,2ZBGG@2|Bacteria,1TSYU@1239|Firmicutes,24E7Y@186801|Clostridia,36PP2@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02375	515620.EUBELI_00659	3.48e-239	669.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,25VPU@186806|Eubacteriaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
ALEKFNDC_02376	428125.CLOLEP_01728	0.0	1314.0	COG0178@1|root,COG0178@2|Bacteria,1TP0A@1239|Firmicutes,24B3G@186801|Clostridia,3WN9G@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
ALEKFNDC_02377	585394.RHOM_05930	1.26e-303	840.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
ALEKFNDC_02378	1226325.HMPREF1548_05145	0.0	1421.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,36EUY@31979|Clostridiaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
ALEKFNDC_02379	1226325.HMPREF1548_05144	3.2e-85	261.0	2A92C@1|root,30Y6D@2|Bacteria,1V59Y@1239|Firmicutes,25HP5@186801|Clostridia,36I7M@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
ALEKFNDC_02380	411490.ANACAC_00529	6.39e-09	57.4	28JJB@1|root,2Z9CE@2|Bacteria,1U6BP@1239|Firmicutes,24B0T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02381	552398.HMPREF0866_02660	3.53e-140	399.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,24E8B@186801|Clostridia,3WQV9@541000|Ruminococcaceae	186801|Clostridia	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ALEKFNDC_02382	742740.HMPREF9474_02619	3.67e-138	400.0	COG0583@1|root,COG0583@2|Bacteria,1V2YI@1239|Firmicutes,24JYF@186801|Clostridia,221P6@1506553|Lachnoclostridium	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02383	742741.HMPREF9475_01536	1.79e-58	192.0	COG1052@1|root,COG1052@2|Bacteria,1TS88@1239|Firmicutes,25CB6@186801|Clostridia	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ALEKFNDC_02384	742740.HMPREF9474_03377	8.9e-121	356.0	COG0119@1|root,COG0119@2|Bacteria,1VBH8@1239|Firmicutes,24PAQ@186801|Clostridia	186801|Clostridia	E	HMGL-like	-	-	-	-	-	-	-	-	-	-	-	-	DmpG_comm,HMGL-like
ALEKFNDC_02385	591001.Acfer_2029	2.54e-224	620.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9EP@909932|Negativicutes	909932|Negativicutes	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
ALEKFNDC_02386	742741.HMPREF9475_02067	2.7e-246	689.0	COG3333@1|root,COG3333@2|Bacteria,1TPE7@1239|Firmicutes,247UH@186801|Clostridia,21YEA@1506553|Lachnoclostridium	186801|Clostridia	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
ALEKFNDC_02387	1226322.HMPREF1545_03351	7.98e-12	67.4	2EFUW@1|root,339M2@2|Bacteria,1VFXY@1239|Firmicutes,24NMR@186801|Clostridia,2N7UU@216572|Oscillospiraceae	186801|Clostridia	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
ALEKFNDC_02388	742740.HMPREF9474_03211	9.01e-116	346.0	COG3181@1|root,COG3181@2|Bacteria,1V0HH@1239|Firmicutes,24HV2@186801|Clostridia,2241Z@1506553|Lachnoclostridium	186801|Clostridia	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
ALEKFNDC_02389	552398.HMPREF0866_02660	2.36e-154	434.0	COG0684@1|root,COG0684@2|Bacteria,1V1ME@1239|Firmicutes,24E8B@186801|Clostridia,3WQV9@541000|Ruminococcaceae	186801|Clostridia	H	Pfam:Methyltransf_6	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
ALEKFNDC_02390	742740.HMPREF9474_02621	4.58e-135	390.0	COG2084@1|root,COG2084@2|Bacteria,1V4MC@1239|Firmicutes,24KB8@186801|Clostridia	186801|Clostridia	I	Domain of unknown function (DUF1932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
ALEKFNDC_02391	1121296.JONJ01000022_gene1517	4.85e-100	305.0	COG0583@1|root,COG0583@2|Bacteria,1V2YI@1239|Firmicutes,24JYF@186801|Clostridia,222VA@1506553|Lachnoclostridium	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02392	1235799.C818_00860	1.71e-76	235.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,27N33@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
ALEKFNDC_02393	585394.RHOM_07420	4.26e-109	315.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
ALEKFNDC_02394	585394.RHOM_07410	7.35e-149	428.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ALEKFNDC_02395	622312.ROSEINA2194_03698	0.0	1144.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia	186801|Clostridia	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
ALEKFNDC_02396	622312.ROSEINA2194_03697	2.14e-118	345.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia	186801|Clostridia	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
ALEKFNDC_02397	585394.RHOM_07395	1.52e-107	320.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia	186801|Clostridia	M	COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
ALEKFNDC_02398	585394.RHOM_07390	2.53e-262	729.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia	186801|Clostridia	E	Dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
ALEKFNDC_02399	585394.RHOM_07385	1.35e-102	310.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia	186801|Clostridia	S	Sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
ALEKFNDC_02400	585394.RHOM_07380	7.65e-62	198.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02401	585394.RHOM_07375	8.89e-101	293.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
ALEKFNDC_02402	585394.RHOM_07370	6.22e-96	283.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia	186801|Clostridia	L	RNA methyltransferase, RsmD family	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
ALEKFNDC_02403	585394.RHOM_07365	6.8e-74	226.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
ALEKFNDC_02404	585394.RHOM_07360	1.91e-102	299.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
ALEKFNDC_02405	622312.ROSEINA2194_03690	9.62e-289	792.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia	186801|Clostridia	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
ALEKFNDC_02406	585394.RHOM_07350	1.3e-42	140.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes	1239|Firmicutes	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
ALEKFNDC_02408	585394.RHOM_15945	6.95e-123	360.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02409	585394.RHOM_09375	3.31e-51	167.0	2AKH0@1|root,31B8X@2|Bacteria,1V6ZY@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
ALEKFNDC_02410	1235790.C805_03566	9.31e-34	117.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,25XC8@186806|Eubacteriaceae	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
ALEKFNDC_02411	585394.RHOM_09365	2.16e-125	382.0	COG0810@1|root,COG0810@2|Bacteria,1UJMR@1239|Firmicutes,251BT@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
ALEKFNDC_02412	483218.BACPEC_02956	5.45e-22	95.9	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,268EB@186813|unclassified Clostridiales	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
ALEKFNDC_02413	585394.RHOM_10170	1.93e-164	469.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia	186801|Clostridia	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
ALEKFNDC_02414	483218.BACPEC_02957	1.59e-143	433.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26BFA@186813|unclassified Clostridiales	186801|Clostridia	NT	Single cache domain 3	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,sCache_3_3
ALEKFNDC_02415	622312.ROSEINA2194_01368	7.71e-79	238.0	COG1051@1|root,COG1051@2|Bacteria,1UUZ0@1239|Firmicutes,24NDR@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
ALEKFNDC_02416	585394.RHOM_09310	3.39e-98	286.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia	186801|Clostridia	G	methylglyoxal synthase	mgsA	-	2.7.1.24,4.2.3.3	ko:K00859,ko:K01734	ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120	M00120	R00130,R01016	RC00002,RC00078,RC00424	ko00000,ko00001,ko00002,ko01000	-	-	-	MGS
ALEKFNDC_02417	585394.RHOM_09305	3.52e-178	499.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
ALEKFNDC_02418	585394.RHOM_09300	4.49e-246	684.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02419	585394.RHOM_09295	2.08e-149	427.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02422	585394.RHOM_13940	3.84e-85	252.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia	186801|Clostridia	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
ALEKFNDC_02423	622312.ROSEINA2194_01023	2.69e-175	504.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02424	622312.ROSEINA2194_01022	9.57e-79	247.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1V48S@1239|Firmicutes,24F7N@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator	bltR	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
ALEKFNDC_02425	411461.DORFOR_00949	1.25e-27	109.0	2CJI5@1|root,32SA3@2|Bacteria,1VAH5@1239|Firmicutes,24MTX@186801|Clostridia,27VSK@189330|Dorea	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
ALEKFNDC_02427	622312.ROSEINA2194_00787	2.75e-304	840.0	COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,24978@186801|Clostridia	186801|Clostridia	P	Sulfate transporter	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
ALEKFNDC_02428	1235793.C809_01839	2.26e-54	171.0	COG3695@1|root,COG3695@2|Bacteria,1UIU9@1239|Firmicutes,25ES2@186801|Clostridia,27UK4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
ALEKFNDC_02429	622312.ROSEINA2194_00788	6.32e-83	247.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
ALEKFNDC_02430	471875.RUMLAC_00843	1.91e-62	197.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3WK3Z@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
ALEKFNDC_02431	585394.RHOM_13905	0.0	1196.0	COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
ALEKFNDC_02432	1226325.HMPREF1548_05938	2.85e-65	200.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,36KQ7@31979|Clostridiaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
ALEKFNDC_02433	622312.ROSEINA2194_02694	1.11e-141	408.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
ALEKFNDC_02434	622312.ROSEINA2194_02695	1.77e-281	769.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
ALEKFNDC_02435	622312.ROSEINA2194_02696	2.59e-277	758.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ALEKFNDC_02436	622312.ROSEINA2194_02697	1.2e-199	553.0	COG0149@1|root,COG0149@2|Bacteria,1UY0I@1239|Firmicutes,248YC@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
ALEKFNDC_02437	622312.ROSEINA2194_02698	0.0	1040.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia	186801|Clostridia	S	Conserved protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
ALEKFNDC_02438	97139.C824_05349	3.47e-189	541.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,36DJD@31979|Clostridiaceae	186801|Clostridia	V	MATE efflux family protein	effD	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02439	622312.ROSEINA2194_02654	5.74e-144	410.0	COG0730@1|root,COG0730@2|Bacteria,1UY5F@1239|Firmicutes,24AJU@186801|Clostridia	186801|Clostridia	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
ALEKFNDC_02440	622312.ROSEINA2194_02653	4.16e-232	642.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
ALEKFNDC_02441	478749.BRYFOR_05178	0.0	1090.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
ALEKFNDC_02442	515620.EUBELI_02051	1.66e-79	265.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,25X4C@186806|Eubacteriaceae	186801|Clostridia	NT	Cache domain	mcpC3	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1
ALEKFNDC_02443	622312.ROSEINA2194_02031	2.78e-157	442.0	COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,24DII@186801|Clostridia	186801|Clostridia	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
ALEKFNDC_02444	585394.RHOM_14750	7.73e-93	280.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
ALEKFNDC_02445	411463.EUBVEN_01409	3.94e-104	312.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,25VP7@186806|Eubacteriaceae	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
ALEKFNDC_02446	411468.CLOSCI_03983	9.98e-93	277.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,21ZN5@1506553|Lachnoclostridium	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
ALEKFNDC_02447	720554.Clocl_3524	1.31e-70	222.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3WS73@541000|Ruminococcaceae	186801|Clostridia	S	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
ALEKFNDC_02448	585394.RHOM_14715	2.1e-82	248.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia	186801|Clostridia	M	Acetyltransferase GNAT family	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
ALEKFNDC_02449	585394.RHOM_14710	7.89e-186	521.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia	186801|Clostridia	P	Mg2 transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
ALEKFNDC_02450	622312.ROSEINA2194_02047	1.33e-193	538.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia	186801|Clostridia	J	Psort location Cytoplasmic, score	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
ALEKFNDC_02451	585394.RHOM_14635	4.26e-262	728.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia	186801|Clostridia	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
ALEKFNDC_02452	585394.RHOM_14630	6.78e-280	770.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia	186801|Clostridia	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
ALEKFNDC_02453	585394.RHOM_06145	5.98e-149	424.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia	186801|Clostridia	G	delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
ALEKFNDC_02455	585394.RHOM_11010	1.81e-242	675.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ALEKFNDC_02456	585394.RHOM_11015	9.49e-147	415.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_02457	585394.RHOM_11020	6.16e-174	503.0	COG0845@1|root,COG0845@2|Bacteria,1V4XJ@1239|Firmicutes,25CIU@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,OEP
ALEKFNDC_02458	622312.ROSEINA2194_04095	5.41e-131	380.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
ALEKFNDC_02459	585394.RHOM_06185	5.03e-154	438.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
ALEKFNDC_02460	585394.RHOM_08170	7.78e-155	440.0	COG1082@1|root,COG1082@2|Bacteria,1U81K@1239|Firmicutes,2492P@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
ALEKFNDC_02461	585394.RHOM_08175	3.51e-128	380.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
ALEKFNDC_02462	585394.RHOM_08175	4.18e-127	377.0	COG5434@1|root,COG5434@2|Bacteria,1TQQW@1239|Firmicutes,24A0R@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 28 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28,Pectate_lyase_3
ALEKFNDC_02463	585394.RHOM_08180	2.95e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1TSYB@1239|Firmicutes,24AKM@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10194	ko02010,map02010	M00202	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.11	-	-	BPD_transp_1
ALEKFNDC_02464	585394.RHOM_08185	4.6e-180	505.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,248DR@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10193	ko02010,map02010	M00202	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.11	-	-	BPD_transp_1
ALEKFNDC_02465	585394.RHOM_08190	5.08e-56	189.0	COG4225@1|root,COG4225@2|Bacteria,1VRB6@1239|Firmicutes,24F2T@186801|Clostridia	186801|Clostridia	S	unsaturated rhamnogalacturonyl hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02466	585394.RHOM_08195	1.23e-256	712.0	COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia	186801|Clostridia	G	extracellular solute-binding	-	-	-	ko:K02027,ko:K10192	ko02010,map02010	M00202,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.11	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
ALEKFNDC_02467	585394.RHOM_04075	2.78e-178	498.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia	186801|Clostridia	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
ALEKFNDC_02468	585394.RHOM_08205	1.56e-292	806.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia	186801|Clostridia	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
ALEKFNDC_02469	585394.RHOM_08210	6.83e-316	864.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia	186801|Clostridia	G	Mannitol dehydrogenase	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
ALEKFNDC_02471	622312.ROSEINA2194_01363	7.33e-248	680.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
ALEKFNDC_02472	585394.RHOM_08065	2.56e-104	303.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia	186801|Clostridia	E	Acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
ALEKFNDC_02474	585394.RHOM_08080	3.23e-288	813.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
ALEKFNDC_02475	585394.RHOM_08085	1.44e-46	156.0	COG1511@1|root,COG1511@2|Bacteria,1VFYY@1239|Firmicutes,24RU2@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02476	585394.RHOM_08090	1.05e-272	777.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia	186801|Clostridia	S	YhgE Pip	pip1	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane,ABC2_membrane_3,DUF3533
ALEKFNDC_02477	742741.HMPREF9475_01822	3.46e-44	149.0	2DMPJ@1|root,32SWG@2|Bacteria,1VCX2@1239|Firmicutes,25CY1@186801|Clostridia,224A1@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02478	622312.ROSEINA2194_04170	1.65e-275	764.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia	186801|Clostridia	L	ImpB MucB SamB family protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
ALEKFNDC_02479	1235802.C823_04227	3.85e-50	166.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,25UWU@186806|Eubacteriaceae	186801|Clostridia	E	Belongs to the HisA HisF family	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
ALEKFNDC_02480	585394.RHOM_05285	2.3e-294	806.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia	186801|Clostridia	E	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
ALEKFNDC_02481	585394.RHOM_05290	1.51e-104	304.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia	186801|Clostridia	K	ANTAR domain protein	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
ALEKFNDC_02482	622312.ROSEINA2194_02823	1.51e-226	628.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
ALEKFNDC_02483	585394.RHOM_06195	6.87e-207	585.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
ALEKFNDC_02484	585394.RHOM_06200	2.45e-268	735.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia	186801|Clostridia	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
ALEKFNDC_02485	585394.RHOM_06205	5.55e-53	168.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia	186801|Clostridia	U	Preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
ALEKFNDC_02486	397291.C804_00163	2.97e-34	134.0	2DY23@1|root,347RM@2|Bacteria,1VQMX@1239|Firmicutes,24UP2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02487	397291.C804_00162	2.08e-47	169.0	COG1396@1|root,COG1396@2|Bacteria,1VC2K@1239|Firmicutes,24NMY@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_02489	644284.Arch_1205	6.77e-12	75.1	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
ALEKFNDC_02490	665950.HMPREF1025_02922	2.54e-134	388.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,27IGQ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
ALEKFNDC_02491	397288.C806_01854	1.7e-84	288.0	COG5279@1|root,COG5279@2|Bacteria,1VEK2@1239|Firmicutes,24SMT@186801|Clostridia,27NZA@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Transglut_core
ALEKFNDC_02492	585394.RHOM_12090	4.06e-201	563.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia	186801|Clostridia	D	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
ALEKFNDC_02495	626369.HMPREF0446_00571	1.08e-27	118.0	COG0438@1|root,COG0438@2|Bacteria,1UZFG@1239|Firmicutes,4ISTK@91061|Bacilli	91061|Bacilli	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02496	877424.ATWC01000003_gene1798	1.35e-26	116.0	COG3274@1|root,COG3274@2|Bacteria,1VFZD@1239|Firmicutes,25D9I@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_02497	585394.RHOM_12020	2.2e-59	202.0	COG3274@1|root,COG3274@2|Bacteria,1V90B@1239|Firmicutes,24IC7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_02498	489825.LYNGBM3L_09380	7.06e-16	84.7	2C7E6@1|root,32JF5@2|Bacteria,1G9FH@1117|Cyanobacteria,1HG1Y@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02499	1235793.C809_03429	2.91e-85	266.0	2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes,24KB5@186801|Clostridia,27MF2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02500	585394.RHOM_07265	3.97e-51	176.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
ALEKFNDC_02501	585394.RHOM_07270	0.0	999.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
ALEKFNDC_02502	585394.RHOM_07275	7.8e-38	127.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia	186801|Clostridia	S	'small, acid-soluble spore protein	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
ALEKFNDC_02503	585394.RHOM_07295	8.03e-259	711.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,24806@186801|Clostridia	186801|Clostridia	S	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
ALEKFNDC_02504	665956.HMPREF1032_02998	2.12e-59	197.0	COG1266@1|root,COG1266@2|Bacteria,1USCY@1239|Firmicutes,24F5M@186801|Clostridia,3WMPA@541000|Ruminococcaceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ALEKFNDC_02505	585394.RHOM_07300	0.0	982.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia	186801|Clostridia	K	Fibronectin-binding protein	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
ALEKFNDC_02507	411489.CLOL250_00770	3.38e-15	87.4	COG5492@1|root,COG5492@2|Bacteria,1VUWB@1239|Firmicutes,24MC1@186801|Clostridia,36VIK@31979|Clostridiaceae	186801|Clostridia	N	COG COG5492 Bacterial surface proteins containing Ig-like domains	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CarboxypepD_reg
ALEKFNDC_02508	1232447.BAHW02000015_gene1139	6.37e-15	79.3	COG0194@1|root,COG4502@1|root,COG0194@2|Bacteria,COG4502@2|Bacteria,1V87A@1239|Firmicutes,24SD2@186801|Clostridia	186801|Clostridia	F	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_kin,NT5C
ALEKFNDC_02509	585394.RHOM_07965	1.6e-261	748.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia	186801|Clostridia	D	SpoIID LytB domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
ALEKFNDC_02510	585394.RHOM_07960	1.52e-148	424.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia	186801|Clostridia	H	Belongs to the UPF0761 family	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
ALEKFNDC_02511	1235802.C823_00629	2.74e-12	66.6	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,25VAC@186806|Eubacteriaceae	186801|Clostridia	J	Phenylalanyl-tRNA synthetase alpha subunit	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
ALEKFNDC_02512	483218.BACPEC_01341	8.48e-154	437.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,267UI@186813|unclassified Clostridiales	186801|Clostridia	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
ALEKFNDC_02513	1256908.HMPREF0373_02472	0.0	1295.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,25UVH@186806|Eubacteriaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
ALEKFNDC_02514	585394.RHOM_07945	2.78e-229	633.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia	186801|Clostridia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
ALEKFNDC_02515	140626.JHWB01000016_gene2464	3.24e-46	151.0	2E11F@1|root,32WHB@2|Bacteria,1VD34@1239|Firmicutes,24NEB@186801|Clostridia	186801|Clostridia	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
ALEKFNDC_02516	1408312.JNJS01000006_gene701	5.48e-34	130.0	COG5434@1|root,COG5434@2|Bacteria,1TSA5@1239|Firmicutes,24B0W@186801|Clostridia,3NHBQ@46205|Pseudobutyrivibrio	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02518	180332.JTGN01000016_gene1038	1.74e-55	188.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia	186801|Clostridia	L	PFAM Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
ALEKFNDC_02519	1232443.BAIA02000044_gene2245	3.5e-112	333.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
ALEKFNDC_02520	1235835.C814_00211	1.16e-186	521.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CMB@186801|Clostridia,3WNAV@541000|Ruminococcaceae	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	2.3.1.245,4.1.2.13	ko:K08321,ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko02024,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map02024	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
ALEKFNDC_02521	1007096.BAGW01000011_gene2259	1.05e-195	551.0	COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24APE@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	lsrB	-	-	ko:K10555	ko02010,ko02024,map02010,map02024	M00219	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.8	-	-	Peripla_BP_4
ALEKFNDC_02522	1232443.BAIA02000044_gene2249	5.58e-140	407.0	COG1172@1|root,COG1172@2|Bacteria,1U2KR@1239|Firmicutes,24AYT@186801|Clostridia	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10557	ko02010,ko02024,map02010,map02024	M00219	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.8	-	-	BPD_transp_2
ALEKFNDC_02523	1235835.C814_00208	3.53e-138	402.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,24CPR@186801|Clostridia,3WNE3@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10556	ko02010,ko02024,map02010,map02024	M00219	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.8	-	-	BPD_transp_2
ALEKFNDC_02524	445972.ANACOL_01230	3.05e-261	728.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,24BDY@186801|Clostridia,3WMXC@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	-	ko:K10558	ko02010,ko02024,map02010,map02024	M00219	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.8	-	-	ABC_tran
ALEKFNDC_02525	1235835.C814_00206	9.91e-121	356.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,3WM1M@541000|Ruminococcaceae	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sugar-bind
ALEKFNDC_02526	1235835.C814_00205	0.0	901.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3WMYR@541000|Ruminococcaceae	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	lsrK	-	2.7.1.189	ko:K11216	ko02024,map02024	-	R11183	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
ALEKFNDC_02527	936550.HMPREF1492_0278	2.32e-70	213.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
ALEKFNDC_02528	622312.ROSEINA2194_03476	3.79e-194	540.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia	186801|Clostridia	G	Fructose-1,6-bisphosphate aldolase, class II	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
ALEKFNDC_02529	585394.RHOM_10085	3.8e-89	264.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
ALEKFNDC_02530	1469948.JPNB01000002_gene3758	6.4e-284	867.0	COG0366@1|root,COG0366@2|Bacteria,1UIVZ@1239|Firmicutes,25GG5@186801|Clostridia,36VA5@31979|Clostridiaceae	186801|Clostridia	GN	Bacterial pullanase-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Alpha-amylase,PUD
ALEKFNDC_02531	622312.ROSEINA2194_00796	2.8e-295	808.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
ALEKFNDC_02532	585394.RHOM_10070	7.02e-130	379.0	COG0721@1|root,COG1670@1|root,COG0721@2|Bacteria,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia	186801|Clostridia	J	acetyltransferase, GNAT family	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
ALEKFNDC_02533	622312.ROSEINA2194_00798	8.43e-314	859.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia	186801|Clostridia	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
ALEKFNDC_02534	622312.ROSEINA2194_04392	4.68e-126	365.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
ALEKFNDC_02535	936574.HMPREF1508_0912	4.87e-118	342.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia	186801|Clostridia	E	MgtC SapB transporter	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
ALEKFNDC_02536	478749.BRYFOR_05620	2.15e-89	270.0	COG1234@1|root,COG1234@2|Bacteria,1V1J7@1239|Firmicutes,24F18@186801|Clostridia	186801|Clostridia	S	Beta-lactamase superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2,UPF0227
ALEKFNDC_02537	478749.BRYFOR_05621	1.39e-146	418.0	COG0584@1|root,COG0584@2|Bacteria,1V404@1239|Firmicutes,24EP5@186801|Clostridia	186801|Clostridia	C	Domain of unknown function	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	DUF4996,GDPD
ALEKFNDC_02538	478749.BRYFOR_05622	0.0	922.0	COG1178@1|root,COG1178@2|Bacteria,1TPMX@1239|Firmicutes,24A64@186801|Clostridia	186801|Clostridia	P	ABC-type Fe3 transport system permease component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
ALEKFNDC_02539	478749.BRYFOR_05623	7.77e-192	538.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
ALEKFNDC_02540	478749.BRYFOR_05624	3.63e-184	520.0	COG1840@1|root,COG1840@2|Bacteria,1U5IH@1239|Firmicutes	1239|Firmicutes	P	solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
ALEKFNDC_02541	478749.BRYFOR_05625	2.97e-288	814.0	COG1609@1|root,COG1653@1|root,COG1609@2|Bacteria,COG1653@2|Bacteria,1V31R@1239|Firmicutes,249JU@186801|Clostridia	186801|Clostridia	K	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_4,SBP_bac_1,SBP_bac_8
ALEKFNDC_02542	397288.C806_02914	1.59e-24	95.5	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,27MB2@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
ALEKFNDC_02543	622312.ROSEINA2194_03540	1.41e-54	174.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02544	585394.RHOM_04945	0.0	897.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia	186801|Clostridia	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
ALEKFNDC_02545	585394.RHOM_04940	2.98e-94	283.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
ALEKFNDC_02546	585394.RHOM_04935	2.13e-238	661.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
ALEKFNDC_02547	622312.ROSEINA2194_03431	0.0	934.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
ALEKFNDC_02548	585394.RHOM_04925	2.06e-216	600.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia	186801|Clostridia	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
ALEKFNDC_02549	585394.RHOM_01040	9.07e-190	532.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia	186801|Clostridia	KT	PFAM Region found in RelA SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
ALEKFNDC_02550	411489.CLOL250_01927	0.0	895.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,36EFF@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
ALEKFNDC_02551	515620.EUBELI_20602	1.2e-51	164.0	2CG7V@1|root,32S3C@2|Bacteria,1UIG6@1239|Firmicutes,25EMK@186801|Clostridia,25ZVA@186806|Eubacteriaceae	186801|Clostridia	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4298,Dabb
ALEKFNDC_02552	515620.EUBELI_20270	3.85e-86	256.0	COG2606@1|root,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,25W9B@186806|Eubacteriaceae	186801|Clostridia	S	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
ALEKFNDC_02553	1280681.AUJZ01000005_gene3017	3.01e-110	334.0	COG0639@1|root,COG0639@2|Bacteria,1V2F7@1239|Firmicutes,24H5G@186801|Clostridia,4BWBP@830|Butyrivibrio	186801|Clostridia	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
ALEKFNDC_02554	1408436.JHXY01000019_gene1391	3.89e-137	396.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,25W58@186806|Eubacteriaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
ALEKFNDC_02555	411467.BACCAP_02128	1.49e-89	270.0	28N6T@1|root,2ZBBM@2|Bacteria,1TS9F@1239|Firmicutes,24DPE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02556	397287.C807_02675	4.96e-55	177.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,27NNV@186928|unclassified Lachnospiraceae	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
ALEKFNDC_02557	1280694.AUJQ01000010_gene2535	3.03e-151	431.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia,3NI14@46205|Pseudobutyrivibrio	186801|Clostridia	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ALEKFNDC_02558	1226325.HMPREF1548_06783	1.2e-131	377.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,36DZG@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_02559	622312.ROSEINA2194_01333	1.56e-84	252.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia	186801|Clostridia	S	Phosphoesterase	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
ALEKFNDC_02560	585394.RHOM_02950	1.12e-114	331.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
ALEKFNDC_02561	622312.ROSEINA2194_01335	2.14e-166	475.0	COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia	186801|Clostridia	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1
ALEKFNDC_02562	585394.RHOM_02935	1.04e-305	844.0	COG4870@1|root,COG4870@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1,Rhodanese
ALEKFNDC_02563	585394.RHOM_02930	1.49e-257	708.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia	186801|Clostridia	L	Belongs to the methyltransferase superfamily	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
ALEKFNDC_02564	585394.RHOM_02925	5.04e-37	127.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
ALEKFNDC_02566	585394.RHOM_02915	0.0	1103.0	COG0664@1|root,COG0664@2|Bacteria,1TSX5@1239|Firmicutes,24A8U@186801|Clostridia	186801|Clostridia	T	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
ALEKFNDC_02567	585394.RHOM_02910	2.52e-219	613.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
ALEKFNDC_02570	1280688.AUJB01000010_gene2801	1.86e-37	137.0	COG0507@1|root,COG0507@2|Bacteria,1VAZW@1239|Firmicutes,24NP3@186801|Clostridia,3NI77@46205|Pseudobutyrivibrio	186801|Clostridia	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02571	585394.RHOM_14775	2.08e-130	375.0	COG1028@1|root,COG1028@2|Bacteria,1TZY6@1239|Firmicutes,248QZ@186801|Clostridia	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
ALEKFNDC_02572	585394.RHOM_14780	0.0	1229.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
ALEKFNDC_02573	33035.JPJF01000028_gene2808	1.69e-126	364.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
ALEKFNDC_02574	622312.ROSEINA2194_02025	1.85e-148	431.0	COG4677@1|root,COG4677@2|Bacteria,1UYI6@1239|Firmicutes,24B29@186801|Clostridia	186801|Clostridia	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
ALEKFNDC_02575	585394.RHOM_14795	1.38e-19	79.7	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02576	397291.C804_00046	2.5e-118	353.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27KG8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
ALEKFNDC_02577	411474.COPEUT_02349	9.63e-40	140.0	COG3868@1|root,COG3868@2|Bacteria,1V4J5@1239|Firmicutes,24GI7@186801|Clostridia	186801|Clostridia	M	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
ALEKFNDC_02578	585394.RHOM_05155	5.91e-156	441.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia	186801|Clostridia	E	Histidinol phosphate phosphatase, HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
ALEKFNDC_02579	350688.Clos_0837	1.08e-119	357.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,36F51@31979|Clostridiaceae	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
ALEKFNDC_02580	428125.CLOLEP_02050	3.7e-197	562.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
ALEKFNDC_02581	1519439.JPJG01000008_gene1174	3.57e-68	213.0	2CBD1@1|root,32SNG@2|Bacteria,1VAVB@1239|Firmicutes,24Q8B@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02582	1226325.HMPREF1548_01463	3.46e-43	157.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,36E5J@31979|Clostridiaceae	186801|Clostridia	K	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_02583	478749.BRYFOR_06199	4.07e-09	59.7	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
ALEKFNDC_02584	411459.RUMOBE_00681	9.93e-151	429.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,3Y0W4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fic
ALEKFNDC_02586	622312.ROSEINA2194_01403	0.0	1481.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia	186801|Clostridia	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
ALEKFNDC_02587	585394.RHOM_10590	8.73e-36	123.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
ALEKFNDC_02588	658088.HMPREF0987_01444	0.0	1458.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,27I5Y@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
ALEKFNDC_02589	658088.HMPREF0987_01443	0.0	1326.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia,27J08@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
ALEKFNDC_02590	585394.RHOM_05815	1.57e-154	436.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
ALEKFNDC_02591	622312.ROSEINA2194_02494	9.41e-261	723.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
ALEKFNDC_02593	1235798.C817_00762	7.92e-165	479.0	28K2E@1|root,2Z9RR@2|Bacteria,1TRJ6@1239|Firmicutes,24F8S@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein (Cas_Csm6)	-	-	-	-	-	-	-	-	-	-	-	-	Cas_Csm6
ALEKFNDC_02594	1297581.H919_06536	1.3e-127	381.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,4HIIN@91061|Bacilli	91061|Bacilli	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
ALEKFNDC_02595	1064535.MELS_0830	4.14e-25	106.0	292FV@1|root,2ZQ01@2|Bacteria,1V62Q@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02596	537007.BLAHAN_06528	2.53e-192	540.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
ALEKFNDC_02597	622312.ROSEINA2194_02467	9.5e-142	402.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia	186801|Clostridia	S	RelA SpoT domain protein	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
ALEKFNDC_02598	585394.RHOM_03635	7.14e-237	677.0	COG2200@1|root,COG2200@2|Bacteria,1TQRN@1239|Firmicutes,247QG@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
ALEKFNDC_02599	622312.ROSEINA2194_00344	3.32e-130	374.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
ALEKFNDC_02600	585394.RHOM_08800	2.63e-154	455.0	COG0457@1|root,COG2199@1|root,COG0457@2|Bacteria,COG3706@2|Bacteria,1TS77@1239|Firmicutes,24E4N@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,TPR_8
ALEKFNDC_02601	585394.RHOM_08805	5.79e-162	468.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia	186801|Clostridia	T	Stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
ALEKFNDC_02602	585394.RHOM_08810	8.41e-232	657.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
ALEKFNDC_02603	622312.ROSEINA2194_02741	1.05e-80	241.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
ALEKFNDC_02604	622312.ROSEINA2194_02742	4.85e-138	398.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
ALEKFNDC_02605	622312.ROSEINA2194_02743	6.42e-156	441.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
ALEKFNDC_02606	585394.RHOM_08830	0.0	979.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
ALEKFNDC_02607	1121115.AXVN01000100_gene829	2.13e-233	644.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3XYJG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N,ADH_zinc_N_2
ALEKFNDC_02608	1519439.JPJG01000036_gene1534	9.6e-114	328.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia,2N8CP@216572|Oscillospiraceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
ALEKFNDC_02609	1519439.JPJG01000036_gene1533	9.45e-262	726.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,2N80X@216572|Oscillospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02610	1001530.BACE01000012_gene2719	1.18e-73	240.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,1RNIW@1236|Gammaproteobacteria,1XUGI@135623|Vibrionales	135623|Vibrionales	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
ALEKFNDC_02611	1209989.TepiRe1_0487	3.65e-103	311.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,42GB7@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
ALEKFNDC_02612	742733.HMPREF9469_02047	2.9e-117	345.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,21XVT@1506553|Lachnoclostridium	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
ALEKFNDC_02613	1298920.KI911353_gene3019	1.97e-155	462.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25KJ2@186801|Clostridia,21Y85@1506553|Lachnoclostridium	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
ALEKFNDC_02614	622312.ROSEINA2194_01729	4.99e-179	502.0	COG0583@1|root,COG0583@2|Bacteria,1TRVX@1239|Firmicutes,24B1W@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02615	622312.ROSEINA2194_01730	3.45e-208	575.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
ALEKFNDC_02616	622312.ROSEINA2194_01731	7.11e-260	716.0	COG0477@1|root,COG0477@2|Bacteria,1TS50@1239|Firmicutes,24BE2@186801|Clostridia	186801|Clostridia	EGP	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
ALEKFNDC_02617	1408312.JNJS01000001_gene1438	2.36e-139	398.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3NH3M@46205|Pseudobutyrivibrio	186801|Clostridia	E	Type I 3-dehydroquinase	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
ALEKFNDC_02618	622312.ROSEINA2194_01735	6.63e-98	290.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia	186801|Clostridia	G	COG COG3090 TRAP-type C4-dicarboxylate transport system, small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ALEKFNDC_02619	622312.ROSEINA2194_01736	4.45e-255	706.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
ALEKFNDC_02620	622312.ROSEINA2194_01737	3.65e-186	524.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia	186801|Clostridia	G	COG COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component	siaP	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
ALEKFNDC_02621	622312.ROSEINA2194_01738	8.4e-172	481.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
ALEKFNDC_02622	622312.ROSEINA2194_02310	4.02e-211	590.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia	186801|Clostridia	G	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
ALEKFNDC_02623	622312.ROSEINA2194_02311	0.0	939.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia	186801|Clostridia	G	UDPglucose--hexose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
ALEKFNDC_02624	585394.RHOM_10930	3.4e-248	686.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia	186801|Clostridia	E	Aminotransferase	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_02625	622312.ROSEINA2194_02313	5.4e-216	601.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
ALEKFNDC_02626	585394.RHOM_10920	8.79e-96	291.0	COG1266@1|root,COG1266@2|Bacteria,1VF60@1239|Firmicutes,24QSC@186801|Clostridia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
ALEKFNDC_02627	585394.RHOM_10915	1.08e-60	187.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia	186801|Clostridia	S	protein, YerC YecD	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
ALEKFNDC_02628	585394.RHOM_10910	1.69e-89	268.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
ALEKFNDC_02629	585394.RHOM_06810	1.1e-157	456.0	28KI7@1|root,2ZA3H@2|Bacteria,1V07J@1239|Firmicutes,24EVH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02630	622312.ROSEINA2194_00916	6.06e-72	229.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24IHF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02631	585394.RHOM_06800	1.82e-176	505.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02632	585394.RHOM_06795	0.0	1231.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02633	585394.RHOM_06790	2.99e-233	645.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia	186801|Clostridia	E	PFAM Aminotransferase class I and II	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
ALEKFNDC_02634	1121115.AXVN01000030_gene3609	2.23e-258	715.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3XZ0K@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
ALEKFNDC_02635	585394.RHOM_04815	7.96e-109	335.0	COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,1TRKG@1239|Firmicutes,249Y4@186801|Clostridia	186801|Clostridia	MT	NlpC p60 family protein	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
ALEKFNDC_02636	622312.ROSEINA2194_00293	9.74e-38	127.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
ALEKFNDC_02637	585394.RHOM_05135	0.0	1207.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia	186801|Clostridia	L	helicase	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
ALEKFNDC_02638	622312.ROSEINA2194_01402	8.35e-199	552.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02639	585394.RHOM_11105	3.82e-192	534.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
ALEKFNDC_02640	585394.RHOM_11110	3.46e-271	744.0	COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia	186801|Clostridia	E	PFAM Cys Met metabolism	mccB	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
ALEKFNDC_02641	585394.RHOM_11115	2.25e-146	418.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
ALEKFNDC_02642	585394.RHOM_11120	0.0	896.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia	186801|Clostridia	C	domain protein	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
ALEKFNDC_02643	585394.RHOM_11125	8.87e-44	158.0	2E4NI@1|root,32ZHC@2|Bacteria,1VGQR@1239|Firmicutes,24RYT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02644	622312.ROSEINA2194_04139	6.17e-140	407.0	COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia	186801|Clostridia	G	pts system	nagE	-	2.7.1.193	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	M00267	R05199	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7	-	-	PTS_EIIB,PTS_EIIC
ALEKFNDC_02645	1235802.C823_05093	9.92e-64	201.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,25X89@186806|Eubacteriaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
ALEKFNDC_02646	1235802.C823_05092	2.62e-125	396.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,25WEQ@186806|Eubacteriaceae	186801|Clostridia	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
ALEKFNDC_02648	632245.CLP_0713	5.29e-134	386.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,36E3F@31979|Clostridiaceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
ALEKFNDC_02649	622312.ROSEINA2194_02236	1.79e-287	786.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
ALEKFNDC_02651	622312.ROSEINA2194_02923	9.12e-69	212.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
ALEKFNDC_02652	1235793.C809_01302	1.23e-126	384.0	2BP58@1|root,32HW3@2|Bacteria,1V8J8@1239|Firmicutes,24HB1@186801|Clostridia,27PAY@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
ALEKFNDC_02653	585394.RHOM_09290	6.83e-132	384.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
ALEKFNDC_02654	585394.RHOM_09285	9.36e-76	233.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia	186801|Clostridia	S	HAD hydrolase, family IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
ALEKFNDC_02655	585394.RHOM_09280	1.22e-144	417.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_02656	585394.RHOM_09275	0.0	904.0	COG1277@1|root,COG3225@1|root,COG1277@2|Bacteria,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia	186801|Clostridia	N	-transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_transp_aux
ALEKFNDC_02659	1256908.HMPREF0373_01181	2.76e-244	680.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
ALEKFNDC_02660	622312.ROSEINA2194_00357	1.81e-29	106.0	2DR14@1|root,339R7@2|Bacteria,1VMNT@1239|Firmicutes,24UVM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02662	1235790.C805_00091	2.53e-09	65.1	2DWVT@1|root,3424F@2|Bacteria,1VWQ8@1239|Firmicutes,252G7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02664	693746.OBV_18260	9e-28	102.0	2B2D6@1|root,33482@2|Bacteria,1VEFH@1239|Firmicutes,24TY9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02665	1256908.HMPREF0373_00463	6.03e-50	159.0	2EBY7@1|root,335XI@2|Bacteria,1VFDN@1239|Firmicutes,24RSH@186801|Clostridia	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
ALEKFNDC_02666	397290.C810_03258	1.71e-72	229.0	COG1876@1|root,COG1876@2|Bacteria,1V69M@1239|Firmicutes,25D75@186801|Clostridia,27TVG@186928|unclassified Lachnospiraceae	1239|Firmicutes	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	CW_binding_1,PG_binding_1,Peptidase_M15_4
ALEKFNDC_02667	397290.C810_04867	1.69e-32	120.0	2B1N9@1|root,31U3S@2|Bacteria,1USHS@1239|Firmicutes,25AHW@186801|Clostridia,27QGU@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02668	626523.GCWU000342_02293	1.14e-131	386.0	COG1609@1|root,COG1609@2|Bacteria,1TSRM@1239|Firmicutes,24BFS@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
ALEKFNDC_02669	1226325.HMPREF1548_06302	1.89e-291	803.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
ALEKFNDC_02670	658086.HMPREF0994_00224	3.09e-100	295.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,27M68@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
ALEKFNDC_02671	585394.RHOM_11690	9.49e-175	500.0	COG4641@1|root,COG4641@2|Bacteria,1UYE0@1239|Firmicutes,24D1Q@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
ALEKFNDC_02672	585394.RHOM_11695	6.42e-221	618.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
ALEKFNDC_02673	585394.RHOM_11700	6.12e-213	610.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
ALEKFNDC_02674	585394.RHOM_11705	1.68e-136	389.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_02675	585394.RHOM_11710	1.83e-161	473.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
ALEKFNDC_02677	748224.HMPREF9436_00019	4.52e-193	539.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WN2S@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ALEKFNDC_02678	1235793.C809_00895	4.8e-235	649.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27JHK@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
ALEKFNDC_02679	1235793.C809_00894	8.03e-217	602.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,27II5@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
ALEKFNDC_02680	1235793.C809_00893	2.47e-188	527.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27KXN@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
ALEKFNDC_02681	1235793.C809_00892	0.0	936.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,27JM8@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
ALEKFNDC_02682	585394.RHOM_11460	1.66e-72	227.0	COG1175@1|root,COG1175@2|Bacteria,1TQHI@1239|Firmicutes,247ZB@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_02683	585394.RHOM_11455	1.16e-168	475.0	COG0395@1|root,COG0395@2|Bacteria,1TSVW@1239|Firmicutes,249KJ@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
ALEKFNDC_02684	585394.RHOM_11450	2.4e-210	591.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
ALEKFNDC_02685	585394.RHOM_11445	2.24e-263	723.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,24A1K@186801|Clostridia	186801|Clostridia	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	-	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_02686	585394.RHOM_11440	4.24e-247	678.0	COG2152@1|root,COG2152@2|Bacteria,1TQE7@1239|Firmicutes,249D0@186801|Clostridia	186801|Clostridia	G	PFAM Glycosidase	-	-	2.4.1.319,2.4.1.320	ko:K18785	-	-	R10811,R10829	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
ALEKFNDC_02687	585394.RHOM_11435	2.42e-177	502.0	COG2755@1|root,COG2755@2|Bacteria,1TS75@1239|Firmicutes,24DPZ@186801|Clostridia	186801|Clostridia	E	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_02688	585394.RHOM_11430	1.48e-161	465.0	COG2755@1|root,COG2755@2|Bacteria,1TQG2@1239|Firmicutes,24A1G@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
ALEKFNDC_02689	622312.ROSEINA2194_02620	3.65e-28	110.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia	186801|Clostridia	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
ALEKFNDC_02690	411483.FAEPRAA2165_03445	2.86e-146	417.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3WHK4@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
ALEKFNDC_02692	622312.ROSEINA2194_00578	0.0	957.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02693	658086.HMPREF0994_04444	1.74e-293	816.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,27IP5@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
ALEKFNDC_02694	658655.HMPREF0988_02667	7.63e-245	682.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,27IAA@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02695	397288.C806_04570	2.21e-05	53.5	COG1345@1|root,COG1345@2|Bacteria,1VU42@1239|Firmicutes,24Y6R@186801|Clostridia,27KHZ@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	FliD_C
ALEKFNDC_02696	585394.RHOM_06765	8.31e-58	181.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
ALEKFNDC_02697	585394.RHOM_06760	7.49e-130	372.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
ALEKFNDC_02698	585394.RHOM_06755	3.12e-61	202.0	COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes,248Y7@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02699	622312.ROSEINA2194_00367	0.0	940.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia	186801|Clostridia	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
ALEKFNDC_02700	585394.RHOM_06750	3.76e-192	542.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia	186801|Clostridia	C	'glutamate synthase	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
ALEKFNDC_02701	748224.HMPREF9436_00833	3.67e-51	164.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,3WKTY@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667,Molybdop_Fe4S4
ALEKFNDC_02702	748224.HMPREF9436_00832	6.47e-227	633.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,3WHBX@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
ALEKFNDC_02703	748224.HMPREF9436_00831	1.54e-251	701.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3WH8P@541000|Ruminococcaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
ALEKFNDC_02704	748224.HMPREF9436_00829	1.07e-101	301.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia,3WM22@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
ALEKFNDC_02705	742735.HMPREF9467_03255	4.45e-206	582.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,21YNU@1506553|Lachnoclostridium	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
ALEKFNDC_02706	411902.CLOBOL_01991	5.03e-37	132.0	COG3090@1|root,COG3090@2|Bacteria,1UHF6@1239|Firmicutes,25Q66@186801|Clostridia,221W6@1506553|Lachnoclostridium	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
ALEKFNDC_02707	742735.HMPREF9467_03257	3.65e-118	352.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24E92@186801|Clostridia,221QU@1506553|Lachnoclostridium	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
ALEKFNDC_02708	622312.ROSEINA2194_03704	9.33e-139	404.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
ALEKFNDC_02709	585394.RHOM_07430	4.38e-142	402.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia	186801|Clostridia	E	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
ALEKFNDC_02710	622312.ROSEINA2194_03708	5.04e-257	711.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
ALEKFNDC_02711	585394.RHOM_07440	5.47e-123	352.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia	186801|Clostridia	E	imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
ALEKFNDC_02712	585394.RHOM_07445	5.08e-269	741.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
ALEKFNDC_02713	397290.C810_00822	1.47e-117	350.0	COG2865@1|root,COG2865@2|Bacteria,1US7F@1239|Firmicutes,24E9U@186801|Clostridia,27MAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
ALEKFNDC_02714	397290.C810_00822	1.51e-120	360.0	COG2865@1|root,COG2865@2|Bacteria,1US7F@1239|Firmicutes,24E9U@186801|Clostridia,27MAH@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
ALEKFNDC_02717	585394.RHOM_05235	2.94e-14	70.5	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02718	585394.RHOM_05230	1.31e-149	445.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02719	585394.RHOM_05225	2.87e-181	513.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ALEKFNDC_02723	585394.RHOM_05165	1.54e-42	147.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia	186801|Clostridia	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
ALEKFNDC_02724	585394.RHOM_05170	3.91e-270	742.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia	186801|Clostridia	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
ALEKFNDC_02725	585394.RHOM_05175	2.9e-172	481.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
ALEKFNDC_02727	585394.RHOM_05185	0.0	954.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
ALEKFNDC_02728	585394.RHOM_05190	2.44e-190	531.0	COG0152@1|root,COG0152@2|Bacteria	2|Bacteria	F	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945,ko:K03566	ko00230,ko01100,ko01110,ko01130,ko02026,map00230,map01100,map01110,map01130,map02026	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	SAICAR_synt
ALEKFNDC_02729	397290.C810_01190	1.26e-113	330.0	COG1309@1|root,COG1309@2|Bacteria,1V8TI@1239|Firmicutes,24F39@186801|Clostridia,27KFG@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
ALEKFNDC_02730	397288.C806_03259	1.57e-13	67.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,27MHD@186928|unclassified Lachnospiraceae	186801|Clostridia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
ALEKFNDC_02731	397288.C806_03259	1.03e-26	101.0	COG3976@1|root,COG3976@2|Bacteria,1VFG0@1239|Firmicutes,24RHT@186801|Clostridia,27MHD@186928|unclassified Lachnospiraceae	186801|Clostridia	C	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
ALEKFNDC_02732	1321784.HMPREF1987_01012	7.57e-106	314.0	COG0716@1|root,COG1143@1|root,COG0716@2|Bacteria,COG1143@2|Bacteria,1TRYM@1239|Firmicutes,247NM@186801|Clostridia,25SY8@186804|Peptostreptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_3,Flavodoxin_5
ALEKFNDC_02733	1280673.AUJJ01000036_gene1542	3.09e-153	447.0	COG2312@1|root,COG2312@2|Bacteria,1V2ED@1239|Firmicutes,24BHP@186801|Clostridia,4BXEN@830|Butyrivibrio	186801|Clostridia	S	Erythromycin esterase	-	-	-	ko:K06880	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Erythro_esteras
ALEKFNDC_02734	445972.ANACOL_01323	4.31e-43	155.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WHT6@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
ALEKFNDC_02735	1235802.C823_05147	3.67e-182	518.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,25VTM@186806|Eubacteriaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
ALEKFNDC_02736	585394.RHOM_08780	1.37e-123	362.0	28H6W@1|root,2ZA4C@2|Bacteria,1UXGN@1239|Firmicutes,24AZN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02737	411469.EUBHAL_02519	6.71e-187	560.0	28N1Z@1|root,2ZB7X@2|Bacteria,1UZID@1239|Firmicutes,24F7M@186801|Clostridia,25Y86@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02738	585394.RHOM_08775	6.14e-184	540.0	28HJQ@1|root,2Z7UU@2|Bacteria,1UPMJ@1239|Firmicutes,24BW1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
ALEKFNDC_02739	585394.RHOM_07450	9.32e-46	160.0	COG3274@1|root,COG3274@2|Bacteria,1VSWJ@1239|Firmicutes,248AQ@186801|Clostridia	186801|Clostridia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
ALEKFNDC_02741	585394.RHOM_07460	0.0	1066.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia	186801|Clostridia	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
ALEKFNDC_02742	585394.RHOM_07465	9.4e-123	355.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia	186801|Clostridia	S	Radical SAM-linked protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
ALEKFNDC_02743	585394.RHOM_07470	1.21e-159	463.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia	186801|Clostridia	J	ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
ALEKFNDC_02744	411463.EUBVEN_00827	4.55e-153	435.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,25VRX@186806|Eubacteriaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
ALEKFNDC_02745	140626.JHWB01000016_gene2319	1.28e-42	159.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20,5.3.1.24	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722,R03509	RC00209,RC00210,RC00700,RC00701,RC00945,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,PRAI
ALEKFNDC_02746	585394.RHOM_06550	8.96e-127	367.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
ALEKFNDC_02747	585394.RHOM_06545	1.19e-114	330.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
ALEKFNDC_02748	585394.RHOM_06540	4.02e-268	743.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
ALEKFNDC_02749	536233.CLO_3167	4.03e-23	101.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,36UPV@31979|Clostridiaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02751	585394.RHOM_08765	3.11e-250	698.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
ALEKFNDC_02752	1235802.C823_04311	1.87e-10	61.6	2EA00@1|root,3345F@2|Bacteria,1VJQ9@1239|Firmicutes,24R0V@186801|Clostridia,25Z91@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
ALEKFNDC_02753	585394.RHOM_08755	3.51e-166	479.0	COG0438@1|root,COG0438@2|Bacteria,1V09V@1239|Firmicutes,24C11@186801|Clostridia	186801|Clostridia	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
ALEKFNDC_02754	585394.RHOM_08750	4.65e-142	406.0	COG1216@1|root,COG1216@2|Bacteria,1UAQP@1239|Firmicutes,25B5D@186801|Clostridia	186801|Clostridia	S	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
ALEKFNDC_02755	585394.RHOM_08745	7.31e-92	290.0	28NI3@1|root,2ZBJM@2|Bacteria,1V27V@1239|Firmicutes,24FTG@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
ALEKFNDC_02756	585394.RHOM_08055	6.66e-115	352.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
ALEKFNDC_02757	585394.RHOM_08050	3.2e-267	738.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02758	585394.RHOM_08035	2.92e-184	515.0	COG0583@1|root,COG0583@2|Bacteria,1TR84@1239|Firmicutes,24BU7@186801|Clostridia	186801|Clostridia	K	lysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
ALEKFNDC_02759	585394.RHOM_08030	1.1e-294	805.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
ALEKFNDC_02760	622312.ROSEINA2194_03857	8.27e-111	318.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
ALEKFNDC_02761	397287.C807_03134	4.51e-64	204.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,27M63@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
ALEKFNDC_02762	1280673.AUJJ01000011_gene1913	2.45e-142	407.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia,4BYE6@830|Butyrivibrio	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
ALEKFNDC_02763	622312.ROSEINA2194_04213	9.79e-296	809.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
ALEKFNDC_02764	622312.ROSEINA2194_04214	0.0	923.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_02765	622312.ROSEINA2194_04215	7.71e-193	536.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
ALEKFNDC_02766	1235790.C805_03039	2.67e-131	438.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,Peptidase_M26_N,SLH,fn3
ALEKFNDC_02767	585394.RHOM_04790	4.58e-279	769.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia	186801|Clostridia	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
ALEKFNDC_02768	1235799.C818_01516	1.8e-47	181.0	COG3210@1|root,COG3210@2|Bacteria,1UJX3@1239|Firmicutes,25FCY@186801|Clostridia,27IUC@186928|unclassified Lachnospiraceae	186801|Clostridia	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
ALEKFNDC_02769	622312.ROSEINA2194_02750	6.81e-43	144.0	2FBHF@1|root,343NR@2|Bacteria,1W0XC@1239|Firmicutes,253BM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02771	585394.RHOM_05270	1.21e-226	633.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia	186801|Clostridia	M	Cbs domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
ALEKFNDC_02772	622312.ROSEINA2194_00306	0.0	906.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
ALEKFNDC_02774	411470.RUMGNA_02192	6.43e-51	166.0	2E6E9@1|root,3311Q@2|Bacteria	2|Bacteria	S	Siphovirus Gp157	-	-	-	-	-	-	-	-	-	-	-	-	Sipho_Gp157
ALEKFNDC_02776	1256908.HMPREF0373_00658	6.98e-135	384.0	2CAZB@1|root,2Z9VC@2|Bacteria,1VAG9@1239|Firmicutes,24DBS@186801|Clostridia	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
ALEKFNDC_02777	397290.C810_05167	6.86e-112	325.0	2DNZD@1|root,32ZWW@2|Bacteria,1VGR6@1239|Firmicutes,24KXA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02778	397290.C810_05169	7.12e-91	269.0	29WTS@1|root,30IF5@2|Bacteria,1V698@1239|Firmicutes,24IGH@186801|Clostridia,27NKM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	ERCC4 domain	-	-	-	-	-	-	-	-	-	-	-	-	ERCC4
ALEKFNDC_02779	1304866.K413DRAFT_0824	4.22e-52	170.0	COG0358@1|root,COG0358@2|Bacteria,1TRW1@1239|Firmicutes,249RY@186801|Clostridia,36I4U@31979|Clostridiaceae	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
ALEKFNDC_02780	585394.RHOM_11465	3.28e-282	779.0	COG1653@1|root,COG1653@2|Bacteria,1TS0C@1239|Firmicutes,249WW@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
ALEKFNDC_02781	585394.RHOM_11475	3.41e-39	140.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_02782	585394.RHOM_11475	5.41e-104	311.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
ALEKFNDC_02783	585394.RHOM_11480	0.0	1127.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
ALEKFNDC_02786	585394.RHOM_05225	1e-181	514.0	COG0630@1|root,COG0630@2|Bacteria,1UHT2@1239|Firmicutes,25EN1@186801|Clostridia	186801|Clostridia	NU	COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
ALEKFNDC_02787	585394.RHOM_05230	2.85e-136	409.0	28I5Y@1|root,2Z892@2|Bacteria,1UYUF@1239|Firmicutes,24CM9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02788	585394.RHOM_05235	5.18e-15	72.4	2EG0W@1|root,339SX@2|Bacteria,1VKDR@1239|Firmicutes,24S7Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02792	622312.ROSEINA2194_00211	0.0	969.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
ALEKFNDC_02793	622312.ROSEINA2194_00215	1.8e-103	301.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
ALEKFNDC_02794	411460.RUMTOR_02154	2.32e-53	182.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,3XZDB@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
ALEKFNDC_02795	352165.HMPREF7215_0139	3.46e-22	94.7	COG2265@1|root,COG2265@2|Bacteria,3TAIZ@508458|Synergistetes	508458|Synergistetes	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
ALEKFNDC_02796	585394.RHOM_10895	2.5e-256	713.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
ALEKFNDC_02798	585394.RHOM_10905	4.07e-226	645.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia	186801|Clostridia	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
ALEKFNDC_02799	585394.RHOM_05735	3.61e-302	839.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
ALEKFNDC_02800	1469948.JPNB01000001_gene792	1.34e-66	212.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,36WXQ@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
ALEKFNDC_02801	622312.ROSEINA2194_02849	2.54e-106	332.0	COG2206@1|root,COG2206@2|Bacteria,1V6WM@1239|Firmicutes,24FPG@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,GGDEF,HD,HD_5,HisKA_7TM
ALEKFNDC_02803	641107.CDLVIII_5672	1.41e-33	124.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,36DWD@31979|Clostridiaceae	186801|Clostridia	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
ALEKFNDC_02804	1280671.AUJH01000002_gene2226	3.01e-173	491.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,4BW72@830|Butyrivibrio	186801|Clostridia	P	PDGLE domain	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
ALEKFNDC_02805	457396.CSBG_01568	2.92e-90	275.0	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,36FJU@31979|Clostridiaceae	186801|Clostridia	P	Cobalt ABC transporter, permease	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
ALEKFNDC_02806	457396.CSBG_01567	1.9e-104	309.0	COG1122@1|root,COG1122@2|Bacteria,1TSSM@1239|Firmicutes,249KS@186801|Clostridia,36VFD@31979|Clostridiaceae	186801|Clostridia	P	ATP-binding protein	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
ALEKFNDC_02808	483218.BACPEC_02744	2.4e-69	221.0	COG1132@1|root,COG1132@2|Bacteria,1US0C@1239|Firmicutes,24EZJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
ALEKFNDC_02810	1235800.C819_02890	4.87e-91	284.0	COG3290@1|root,COG3290@2|Bacteria,1VFJZ@1239|Firmicutes,24RD0@186801|Clostridia,27T94@186928|unclassified Lachnospiraceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
ALEKFNDC_02812	1410653.JHVC01000007_gene446	4.7e-135	394.0	28H6R@1|root,2Z7J3@2|Bacteria,1TQ2I@1239|Firmicutes,247QF@186801|Clostridia,36EPD@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02813	585394.RHOM_07325	3.82e-141	404.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
ALEKFNDC_02814	585394.RHOM_07330	6.72e-96	282.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia	186801|Clostridia	K	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
ALEKFNDC_02815	622312.ROSEINA2194_03686	5.82e-166	469.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia	186801|Clostridia	S	TIGR00255 family	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
ALEKFNDC_02816	622312.ROSEINA2194_03687	1.19e-46	150.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
ALEKFNDC_02817	622312.ROSEINA2194_03688	1.04e-117	340.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
ALEKFNDC_02818	471875.RUMLAC_00642	3.52e-146	420.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
ALEKFNDC_02819	622312.ROSEINA2194_03684	3.18e-56	179.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,24HAM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02820	1042156.CXIVA_21730	1.57e-12	64.7	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,36M8R@31979|Clostridiaceae	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
ALEKFNDC_02821	585394.RHOM_07305	2.46e-208	590.0	COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,248TP@186801|Clostridia	186801|Clostridia	E	Oligoendopeptidase f	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
ALEKFNDC_02822	180332.JTGN01000002_gene5839	1.2e-85	260.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
ALEKFNDC_02823	457412.RSAG_00991	3.07e-50	160.0	COG1813@1|root,COG1813@2|Bacteria,1UI13@1239|Firmicutes,25FPX@186801|Clostridia,3WSNY@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_02824	518637.EUBIFOR_00136	3.74e-59	185.0	COG4679@1|root,COG4679@2|Bacteria,1VB8K@1239|Firmicutes	1239|Firmicutes	S	Toxin-antitoxin system, toxin component, RelE family	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
ALEKFNDC_02825	1280668.ATVT01000007_gene1190	3.69e-21	84.7	COG2944@1|root,COG2944@2|Bacteria,1VE47@1239|Firmicutes,24NNY@186801|Clostridia,4C019@830|Butyrivibrio	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
ALEKFNDC_02826	1280694.AUJQ01000009_gene361	1.08e-99	301.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3NGZA@46205|Pseudobutyrivibrio	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
ALEKFNDC_02827	622312.ROSEINA2194_04368	3.57e-79	236.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01195	ATP-synt_DE,ATP-synt_DE_N
ALEKFNDC_02828	622312.ROSEINA2194_03516	1.37e-248	691.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
ALEKFNDC_02829	1226325.HMPREF1548_06953	6.12e-12	69.7	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,36JHG@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02830	622312.ROSEINA2194_03681	2.31e-234	645.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia	186801|Clostridia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
ALEKFNDC_02831	742765.HMPREF9457_03255	3.58e-145	422.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,27V3C@189330|Dorea	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
ALEKFNDC_02833	1121115.AXVN01000060_gene470	1.27e-106	322.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
ALEKFNDC_02834	1121115.AXVN01000060_gene470	1.14e-271	751.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
ALEKFNDC_02835	1121115.AXVN01000060_gene471	6.16e-91	272.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
ALEKFNDC_02836	622312.ROSEINA2194_04219	0.0	1008.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
ALEKFNDC_02837	1235798.C817_00761	5.09e-44	145.0	COG1343@1|root,COG1343@2|Bacteria,1VFRC@1239|Firmicutes,24R2N@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
ALEKFNDC_02838	1235798.C817_00760	9.92e-186	522.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
ALEKFNDC_02839	1121405.dsmv_0680	2.46e-26	113.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.2.1.14	ko:K01183,ko:K03791	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18,GH19	-	Trypsin,Trypsin_2
ALEKFNDC_02841	411459.RUMOBE_02158	8.98e-18	82.4	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,24I7T@186801|Clostridia,3Y0BR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
ALEKFNDC_02842	518637.EUBIFOR_00728	7.36e-34	116.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
ALEKFNDC_02844	411461.DORFOR_01848	5.39e-17	79.7	COG1143@1|root,COG1143@2|Bacteria,1UI2X@1239|Firmicutes,25EBS@186801|Clostridia	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Flavodoxin_5
ALEKFNDC_02846	397291.C804_01035	9.88e-19	86.7	2DVV1@1|root,33XAM@2|Bacteria,1VVCM@1239|Firmicutes,251DN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
ALEKFNDC_02847	585394.RHOM_10725	3.17e-60	192.0	28IYH@1|root,2Z8W7@2|Bacteria,1V89I@1239|Firmicutes,24MQ8@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (Hypoth_ymh)	-	-	-	-	-	-	-	-	-	-	-	-	Hypoth_Ymh
ALEKFNDC_02849	1410630.JNKP01000003_gene969	8.97e-52	166.0	COG1670@1|root,COG1670@2|Bacteria,1V4IY@1239|Firmicutes,24FWK@186801|Clostridia,27TFI@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
ALEKFNDC_02850	1121098.HMPREF1534_02355	1.37e-52	169.0	COG1309@1|root,COG1309@2|Bacteria,4NNNT@976|Bacteroidetes,2FS2Z@200643|Bacteroidia,4AMMD@815|Bacteroidaceae	976|Bacteroidetes	K	transcriptional regulator, TetR family	qacR	-	-	-	-	-	-	-	-	-	-	-	TetR_C_5,TetR_N
ALEKFNDC_02852	1235800.C819_04222	1.8e-45	163.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,27IRR@186928|unclassified Lachnospiraceae	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
ALEKFNDC_02860	1469948.JPNB01000001_gene1053	2.88e-41	144.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,36DQV@31979|Clostridiaceae	186801|Clostridia	S	ABC transporter	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
ALEKFNDC_02861	411462.DORLON_02356	1.11e-47	160.0	COG3326@1|root,COG3738@1|root,COG3326@2|Bacteria,COG3738@2|Bacteria,1V2SQ@1239|Firmicutes,24F5T@186801|Clostridia,27XA3@189330|Dorea	186801|Clostridia	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
ALEKFNDC_02862	1280698.AUJS01000002_gene2781	1.15e-45	152.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,27W5E@189330|Dorea	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
ALEKFNDC_02863	1280698.AUJS01000065_gene668	2.85e-16	78.2	2CC51@1|root,2Z7IU@2|Bacteria,1TQNI@1239|Firmicutes,24DDD@186801|Clostridia	186801|Clostridia	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2397
ALEKFNDC_02864	585394.RHOM_11915	1.41e-27	107.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia	186801|Clostridia	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
## 2617 queries scanned
## Total time (seconds): 405.2042922973633
## Rate: 6.46 q/s