LOCUS       c00089_gnlPro..        10250 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDAIIKBL_89.
ACCESSION   c00089_gnlPro..
VERSION     c00089_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:25:30
            Original ID  :: gnl|Prokka|GDAIIKBL_89
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10250
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10250
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:9381]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..9381
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_eut-pdu-related"
                     /protocluster_number="1"
     cand_cluster    1..10250
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="GR_eut-pdu-related"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10250
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="GR_eut-pdu-related"
                     /region_number="1"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_radical,
                     Gly_radical_scatole, PFL-like, PFL_6_pcresol, PFL_acetate1,
                     PFL_acetate2, PFL_proline, PFL_toluene]) and minimum(2,
                     [Aldedh, EutN_CcmL, EutQ, PTAC, PduV-EutP]) and not
                     (PFL_9_tma or Gly_8-9_TMA or NRDD) and not EutB and not
                     EutC and not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..614)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PTAC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_1"
                     /sec_met_domain="PTAC (E-value: 5.6e-30, bitscore: 93.0,
                     seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LESNNIELITRMVIQAINQNEKKGDGFMVPIGVSARHIHLTQEHV
                     EALFGPGYQLTKKKELMGGQFASNETVTIVGLKLRAIENVRILGPVRKASQVEVSATDA
                     IKLGMNVPVRESGDVAGSAPIAIVGPKGAVYLKEGCIVAMRHIHMSPKDAQAAGVKDGD
                     IVSVKADNERGTIFNQVKIRVDDSFTLEMHIDTDEANAAKI"
     CDS             complement(700..1176)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.4; E-value:
                     1.4e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg89_2"
                     /sec_met_domain="BMC (E-value: 2.4e-32, bitscore: 100.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEKKPEADKNAPKKAAAPRRTKAKTSSKPEVKAQTADTAAETA
                     NKTESQKEQIKETVSHKEEKVMTQEALGMVETRGLTAAIEAADQMCKAANVALVGTEKI
                     GSGLVTVMVRGDVGAVKSAVESGSAAASRLGELVATHVIPRPHTDVEKILPVLK"
     CDS             complement(1176..1478)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 78.4; E-value:
                     1e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg89_3"
                     /sec_met_domain="BMC (E-value: 1.8e-25, bitscore: 78.4,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKSYGFIEITGVVAAIDALDIMCKTADVELASWERKLGGRLVTI
                     IVEGDVSAVTEAVNAAATGAIKKPVSYAVIARPHEEIVRMVELSASRWKNNQGDE"
     CDS             complement(1515..1790)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 100.7; E-value:
                     1.1e-31)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg89_4"
                     /sec_met_domain="BMC (E-value: 1.9e-32, bitscore: 100.7,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQEALGMVETRGLTAAIEAADAMTKAAEVALVGTEKIGSGLVTV
                     MVRGDVGAVKAAVESGSAAASRLGELVATHVIPRPHTDVEKILPSI"
     CDS             complement(1863..2177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BMC"
                     /gene_functions="encapsulation (smcogs) SMCOG1011:Bacterial
                     Microcompartment (BMC) domain (Score: 75.8; E-value:
                     6.6e-24)"
                     /gene_kind="encapsulation"
                     /locus_tag="ctg89_5"
                     /sec_met_domain="BMC (E-value: 1.2e-24, bitscore: 75.8,
                     seeds: 429, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEAVGILEVFGLATAFVAGDAGCKAANVRLEVFDKNKPANADSL
                     PVPLLVCIKFRGSVTDVTAAVEAGMEVANRMTGVVQHYVIPNPEEGTEKMLKISALDKD
                     "
     CDS             complement(2273..3496)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_6"
                     /sec_met_domain="ADH_N (E-value: 2.7e-17, bitscore: 52.3,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.9e-23, bitscore:
                     71.9, seeds: 88, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDMNNVNIEEIVKQVLSGMTGNAPAAATVSAPAATTGIPKTARVA
                     VLTEKEHFELKEYPIPPIGDDDILVKVEGCGVCGTDAHEFKRDPFGLIPVALGHEGTGE
                     IVAMGKNVKVDTAGKPVKVGDKVVTCMIFKDDPEITMFDLNKKNVGGADVYGLLPDDDV
                     HLNGWFSDYIFLRGGNFGTTFFNVSDLDLDSRILIEPCAVLVHAVERAKTTGILRFNSR
                     VVVQGCGPIGLICIAVLRTMGVEHICAVDGNEKRLEFAKRMGADTSVNFMNFKGIEALT
                     EAVKEAQGGHLADFAFQCTGNPKAHANIYKFIRNGGGLCELGFFINGGDATINPHFDLC
                     SKEINLVGSWVYTLRDYVTTFDFLKRANAIGLPMSELITDKFPLEQINEALQTNLAMTG
                     LKIAVVNK"
     CDS             complement(3524..4912)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Aldedh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_7"
                     /sec_met_domain="Aldedh (E-value: 1.4e-37, bitscore: 118.7,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPINENMVQEIVQEVMAKMQIADAPTGKHGIFKEMNDAIEAAKKS
                     QLIVKKMSMDQREKIITCIRKKIKENAEVMARMGVEETGMGNVGDKILKHHLVADKTPG
                     TEVITTTAWSGDRGLTLIEMGPFGVIGAITPCTNPSETILCNTMGMLAGGNTVVFNPHP
                     AAIKTSIYAINLLNEASLECGGPDNIAVTVEKPTLETSNVMMKHKDIPLIAATGGPGVV
                     TAVLSSGKRGIGAGAGNPPALVDETADIRKAATDIVNGCTFDNNLPCIAEKEIVAVSSI
                     VDELMHYLVTENDCYLASKEEQDKLTEVVLAGGKLNRKCVGRDARTLLSMIGVNAPANI
                     RCIVFEGPKEHPLITTELMMPILGVVRARDFDDAVEQAVWLEHGNRHSAHIHSKNIDNI
                     TKYAKAIDTAILVKNAPSYAALGFGGEGYCTFTIASRTGEGLTCASTFTKRRRCVMADS
                     LCIR"
     CDS             complement(4942..5805)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldolase_II"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_8"
                     /sec_met_domain="Aldolase_II (E-value: 4.5e-47, bitscore:
                     149.9, seeds: 389, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNEYEIKKQICDIGRRIYSRNMVAANDGNISVKLNDNEFLCTPT
                     GVSKGFMTPEYICKVDREGNVIQANPGFKPSSEIKMHMRVYEKRPDVGSVVHAHPIYAT
                     SFAIAGIPLTQPIMPEAVISLGCVPIAEYGTPSTMEIPDNLEKYLPYFDAVLLENHGAL
                     TWSTDLNAAYMKMESVEFYAQLLYQSKVLGGPKEFDEKNIEKLYEIRRKFGMAGKHPAN
                     LCLNKDGKNCHNCGGACQDGEFKKFPGYQYDFVGGDSKPAENNAASDAQLVAEITKQVM
                     AQLGMK"
     CDS             complement(5991..6782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg89_9"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-28, bitscore:
                     89.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLDTKGRVFDVQKYSIHDGPGIRTIVFLKGCVLRCKWCCNPES
                     QEYKIQTMKVQGEDKVIGRDVTVREMIEEVEKDRVYYYRSGGGMTLSGGECLCQPEFAG
                     ALLRAAKERGISTAIESMACAKWETIETILPYLDTYLMDIKHTNPAKHKEFTGRSNELM
                     MENARKVALSGKTRLVIRVPVIPTFNDTVEEIQGIARFADTLPGVDKIHLLPYHRLGQD
                     KYEGLGRPYLMGNVEPPSKEHMETLKKAVHAVCGLDCQIGG"
     CDS             complement(6856..9381)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: Gly_radical"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_eut-pdu-related: PFL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg89_10"
                     /sec_met_domain="Gly_radical (E-value: 2.4e-36, bitscore:
                     114.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL-like (E-value: 2.1e-264, bitscore:
                     868.5, seeds: 123, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKFQTSDIPKSPRIQKLVDALYEHMPVIESARAKLITESYKETE
                     GEPIITRRAKAFAHILHNIPIIIRDNELIVGSSTIAPRGCQTFPEFSYEWLEAELDTVA
                     TRTADPFEIAEETKAELKEADKYWKGKTTSELATSYMAPEAIKAIEHNIFTPGNYFYNG
                     VGHVTVKYWEVLETGFEGIMEKAQKELDGCSVGDGNYARKSHFLEAVILSCKAVIDYAG
                     RYAKLAQEMAAQTSDPVRKQELFVIAENCSRVPAKGAQNFYEACQSFWFVQQLLQMESS
                     GHSISPGRFDQYMYPYYKKDMEAGTITREFAQELMDCIWVKLNDLNKCRDAASAEGFAG
                     YSLFQNLIAGGQNKEGEDVTNDLSVMCIQASMHVHLPAPSLSVRVWNGSPHEFLIKAAE
                     LTRTGIGLPAYYNDEVIIPALQNRGLSLEDAREYNIIGCVEPQKAGKTEGWHDAAFFNM
                     CRPLELVFSNGMDKGEMVGIPTGDVTQMKTFDEFFDAYKKQMEYCISLLVNADNAIDVA
                     HAERCPLPFLSCMIDDCLKEGKSVQEGGAVYNFTGPQGFGIANMADGLFAIRKLVYEDK
                     KVSMKELKEALAWNYDKGLDAQSAGDMTEMIMKAMQKAGRNVDASTAEGLMKTFMGMKP
                     GEQKTQRFKEIHDMIDEVPKFGNDIPEVDYFAREVAYTYSKPLQKYNNPRGGKFQAGLY
                     PVSANVPLGGQTGATPDGRYAHTPVADGVSPSAGKDVKGPTAAATSVSRLDHFIVSNGT
                     LFNQKFHPSALSGREGLEKFVALIRGYFDQKGMHMQFNVVDRQTLLDAQEHPEKYKHLV
                     VRVAGYSALFTTLSRSLQDDIIRRTEQGF"
     CDS             complement(9765..10148)
                     /locus_tag="ctg89_11"
                     /transl_table=11
                     /translation="MKITEELLNEMKIKDENFSDGLIKPDGDYVRIPRGHLHGMMELLP
                     WTENEIWKMIPDDDSPLFWLIEKTGCVLTDYNNSIGMKMTPAQQTVFDMMRKHGVLTDD
                     YYDLTKQREKVREAREQKENRKQ"
ORIGIN
        1 gcaatctttg ctgcatttgc ttcatctgta tcaatatgca tttccagtgt aaagctgtcg
       61 tctacacgga ttttgacctg attgaagatg gttcctctct cattatctgc ctttactgat
      121 acgatatcgc cgtccttcac acctgcagcc tgtgcatctt tcggagacat atgtatatgg
      181 cgcattgcca cgatacatcc ctctttcaga taaacggctc cttttggacc tacgattgcg
      241 attggtgcac ttcctgcaac gtctccggat tcgcgaaccg gaacattcat tccaagctta
      301 atggcatctg tcgcagatac ctcaacctgt gaagctttac gcaccggtcc aaggattctt
      361 acattctcaa tggcacgaag tttcagtccc acaatggtaa ctgtttcatt agaagcaaac
      421 tgacctccca tcagctcttt cttcttcgta agctgatatc cgggtccgaa caatgcttct
      481 acatgttcct gtgtcaggtg aatgtgtctt gcggaaaccc cgatgggaac catgaatcca
      541 tcgccttttt tttcattctg attgattgcc tgaatgacca ttctggtaat cagttcaata
      601 ttattagatt ccaagaatac acctgctttc tgtcaaatat gacggattat aaccatccgg
      661 cagtctgctg tgcagatacc ggacagttac gatggattac tattttaata caggcaggat
      721 tttctctaca tctgtatgtg gtcttgggat tacgtgtgta gcaactaatt caccaagtct
      781 ggatgctgct gcgcttccgc tttctactgc tgatttaaca gctcctacat ctccacgtac
      841 cataactgtt acaagtccgg atccgatctt ctctgttcct actaatgcta cgttagcagc
      901 cttgcacatc tggtctgctg cttcgattgc tgctgtaagt cctctggttt ctaccattcc
      961 taatgcttcc tgtgtcataa ctttttcctc cttatgagat actgtttcct ttatctgttc
     1021 tttctgggat tctgttttat ttgctgtttc tgccgccgta tctgccgtct gagcttttac
     1081 ttccggtttt gaagaagttt ttgctttcgt tcttcttgga gcggctgcct ttttaggggc
     1141 atttttatct gcttccggtt tcttctcttc agccattatt catccccctg attgttcttc
     1201 cagcgacttg cacttaattc caccattctg acgatttctt catgaggacg tgcaattact
     1261 gcataactta ccggtttctt gatcgcacct gtcgctgctg catttactgc ttctgtaacg
     1321 gcagatacat cgccttcaac tataatagta accagtcgtc cgcccagctt acgttcccat
     1381 gacgccagct caacgtctgc agttttgcac atgatgtcca gtgcatcgat tgctgcaacg
     1441 acaccagtga tttctataaa tccatatgat ttactcatga gcgaactcct tttttatact
     1501 tctcaatctg ctggtcagat gcttggaagg attttctcta cgtctgtatg aggtctcgga
     1561 attacatgag tagcaactaa ttcgccaagt ctggatgctg ctgcgcttcc gctttctact
     1621 gctgccttaa cagctcctac gtctccgcgt accataactg ttacaagtcc ggatccgatc
     1681 ttctctgttc ctactaatgc tacttcagct gcttttgtca ttgcatcagc tgcttcaatt
     1741 gctgctgtaa gtcctctggt ttctaccatt cctaatgctt cctgtgccat ttctgcttcc
     1801 tcctgaatct acaaataaat atctgattat attttaactg atgcccaatg gatatgcaac
     1861 tgctaatcct tatccagggc gctgatcttc agcatttttt ccgttccctc ttccgggttc
     1921 gggatcacat aatgctgtac cacaccagtc attctgtttg caacttccat gcctgcttcc
     1981 acagccgctg taacatcagt tacacttcct ctgaatttaa tgcagacaag gagcggtacc
     2041 ggcaggctgt cagcattggc tggtttgttt ttatcaaaaa cctccaggcg gacatttgct
     2101 gccttacatc cggcatcgcc tgctacaaag gctgtcgcca gcccgaatac ctctaaaatt
     2161 cctacagctt ctgccatttc ttttctcctc tattgccagg cttattattt gttgctactg
     2221 ttcactccgt tcacagcaat actctttgcg ggatattacc ggtgaacagt aactatttgt
     2281 ttacaactgc gatcttaagt cctgtcattg ccaagtttgt ctgaagagct tcgttgatct
     2341 gctctaacgg gaatttgtct gtaattaact cagacattgg aagaccgatt gcatttgctc
     2401 tcttaaggaa atcaaatgtt gtaacataat ctctgagagt gtaaacccag gaaccaacca
     2461 gattgatttc tttggagcaa agatcaaagt gcgggttaat tgtagcatct ccaccattga
     2521 taaagaaacc aagttcgcaa aggccgccgc cgttacggat aaatttataa atatttgcat
     2581 gagcttttgg atttcctgta cactggaatg caaaatctgc aaggtgtcca ccctgtgctt
     2641 cttttacagc ctctgtcagt gcttcgattc ctttgaagtt catgaagtta acgcttgtat
     2701 ctgctcccat tctcttcgca aattcaagac gtttctcatt tccgtctact gcgcagatat
     2761 gttctacgcc catagtacga agtactgcaa tgcagatcag accgattggt ccgcagccct
     2821 gaactacaac tctgctgttg aaacgaagga ttccggttgt ttttgctctc tcaactgcat
     2881 gtacaagtac tgcacatggc tcgatgagga ttcgggaatc tagatccaga tcacttacat
     2941 taaagaatgt agttccgaaa tttccacctc ttaagaagat gtaatcggaa aaccatccgt
     3001 taagatgtac atcatcatcc ggaagaagtc catatacgtc agctccacct acgttcttct
     3061 tgttcaggtc gaacattgtg atttccggat catctttaaa gatcatacag gtaacgactt
     3121 tatcgccaac ctttacaggt tttcctgcag tatctacttt aacattctta cccatagcca
     3181 cgatttcacc tgtaccttca tgtccaagtg ctaccgggat caggccaaat ggatctcttt
     3241 taaattcatg tgcatctgta ccacacacac cgcatccttc aactttaacc aggatatcgt
     3301 catctccaat cggaggaatc ggatattctt tcagttcgaa atgttccttt tcagttaata
     3361 cagctactct ggctgtcttc gggattccag ttgttgctgc cggtgcagaa actgttgctg
     3421 ctgccggtgc atttcctgtc atgccggaga gaacctgttt cacgatttct tctatattta
     3481 cattattcat gtccatgttc tttctctcct taactcatca tctttaacga atgcaaaggc
     3541 tgtctgccat tacgcagcgt cttctcttgg taaatgtact tgcgcaggta agaccttcac
     3601 ctgtacggct tgcgattgta aatgtacaat agccttcacc gccaaatcct aatgcagcat
     3661 aggatggtgc attctttaca aggattgctg tatcaattgc tttcgcatat tttgtaatat
     3721 tatcaatatt ctttgaatgg atatgtgcag aatggcgatt tccgtgttct aaccatactg
     3781 cctgttccac tgcatcatca aaatctcttg ctcttactac accaaggatc ggcatcataa
     3841 gctctgttgt gatcagcgga tgttccttcg gtccttcaaa tacgatacag cggatatttg
     3901 ccggtgcatt gacaccgatc atggaaagaa gtgttcttgc gtcacgtccg acacatttac
     3961 ggttcagttt tccgcctgcc agaactactt ctgtaagttt atcctgttct tctttagatg
     4021 caagataaca atcattctca gttacaagat aatgcatcaa ctcatctacg atagaagaaa
     4081 ctgctacgat ctctttctct gcgatacatg gaagattgtt atcaaatgta catccgttta
     4141 caatgtctgt tgccgcttta cggatgtcag ctgtttcatc aacaagtgcc ggagggtttc
     4201 ctgcacctgc accaatgcca cgtttgccgg aagaaagaac tgcagttaca actccaggtc
     4261 cgccggttgc agcgataagc gggatgtctt tatgtttcat catcacattg cttgtctcaa
     4321 gtgtaggttt ctctacagta actgcaatgt tgtcaggacc accgcactct aatgatgctt
     4381 catttaaaag attgattgca taaatggaag ttttgatcgc tgcaggatga ggattgaata
     4441 caactgtatt tcctcctgca agcattccca ttgtattaca taaaattgtt tcacttggat
     4501 tggtacatgg agtaatcgca ccgatcacac cgaaaggtcc catttcaata agagttaatc
     4561 ctctgtctcc tgaccatgca gttgttgtaa taacttctgt tcccggtgtc ttatcagcta
     4621 cgagatgatg tttgagaatc ttatctccta catttcccat accggtctct tccacaccca
     4681 tgcgtgccat tacttctgca ttttctttta ttttcttacg aatgcaggta ataatttttt
     4741 ctctctgatc catggacatt ttctttacaa taagctgtga tttcttggca gcttcaattg
     4801 catcattcat ttctttgaaa atgccatgtt tgccagtcgg agcgtctgct atctgcattt
     4861 ttgccataac ttcctgtaca atttcctgta ccatattctc attaattggc atgagactgt
     4921 cctccttgat tatctatgct cttatttcat tcctaactga gccattactt gttttgtaat
     4981 ctcagcaact aactgtgcat cagatgcagc attattctct gccggttttg aatctccacc
     5041 tacgaaatca tactgatatc cagggaattt cttgaattct ccgtcctgac atgctccacc
     5101 gcagttatga cagttcttgc cgtctttgtt caggcagagg tttgccggat gtttaccagc
     5161 cataccgaat ttacgacgaa tttcataaag tttctcaatg ttcttctcat caaattcctt
     5221 aggtccgcca agaacttttg actgatacag aagctgtgcg tagaactcaa cagattccat
     5281 cttcatgtaa gctgcgttta agtctgtgct ccatgtcagt gctccatggt tctcaagaag
     5341 aactgcatcg aaatatggaa ggtatttttc aagattatcc ggaatctcca ttgtagatgg
     5401 tgtaccgtat tcagcgatcg gaacgcatcc aagtgagata actgcttcag gcatgatcgg
     5461 ctgtgtcagc ggaatacctg caattgcaaa agatgttgca taaatcggat gagcatgcac
     5521 aacagaacct acgtccggtc tcttctcata aactctcata tgcattttga tttcagagga
     5581 tggtttgaat cccgggttag cctggatcac atttccttct ctgtctactt tacagatata
     5641 ctccggtgtc ataaaacctt tggatacacc tgtaggtgtg caaagaaatt cgttgtcgtt
     5701 cagttttaca gagatgttac catcgtttgc agctaccatg ttgcggctgt agattcttct
     5761 tccgatgtcg cagatctgtt ttttgatttc atattcgttt accatgctca ttttcctcct
     5821 taaggcattg atatagtttt tgacgtttct acctgtgatt ttacactatc ggtcataaaa
     5881 agtcaataca tttccgttgt tttatgttgt ttttacaggt tttattgtgt tgtttttgtt
     5941 tgtttttttc tttttttatt ccaataatcg tatcagatgc aaaaaatgcc tcatccaccg
     6001 atctgacagt ccagaccgca gaccgcatgt actgcctttt ttaatgtttc catatgttct
     6061 ttggacggtg gttccacatt tcccatcaga tatggtctgc caagtccctc atatttatcc
     6121 tgtccaagtc tgtgatacgg aagaagatga atcttgtcca ctccgggaag tgtgtctgca
     6181 aaccttgcaa tcccctggat ttcctccact gtatcattaa atgtgggtat caccggtaca
     6241 cggattacca gcctggtttt accggaaagc gccacttttc tggcattttc catcatcagt
     6301 tcattggaac gtcctgtaaa ttctttatgt ttcgcaggat ttgtatgttt aatatccatt
     6361 aaataagtat ccagatacgg taagattgtc tcaatcgtct cccattttgc acatgccata
     6421 ctctcgatcg cagtagaaat ccctctctct ttggcagctc tcagaagtgc tcctgcaaat
     6481 tccggctgac agagacattc tccgccggaa agagtcatac ctccgcccga gcggtaatag
     6541 tataccctgt ctttctcaac ttcttcaatc atctccctga ctgtcacatc acgtccgatg
     6601 accttgtctt ctccctgcac tttcattgtc tggatcttat attcctgaga ttccggattg
     6661 cagcaccatt tgcaccgcag gacacaacct ttcagaaata cgatcgtcct tatacccggt
     6721 ccatcatgaa tagaatattt ctggacatca aacactctgc cctttgtatc caaatagtcc
     6781 atgcttttcc tttcttattc tgttatccat acatcctctg cctgtcactt ttacttcctt
     6841 caaaaaacat ctgaatcaga agccctgttc tgtacgacgg atgatatcat cctgaaggga
     6901 acgggaaagt gtcgtaaaca gtgcactgta gcctgccacg cgtactacca gatgtttata
     6961 tttctcagga tgttcctgtg catccagcag tgtctgcctg tcaactacat taaactgcat
     7021 gtgcattccc ttctggtcaa agtatccgcg gatcagtgca acgaatttct ccagtccctc
     7081 tcttcctgaa agtgcggatg ggtgaaattt ctgattaaag agtgttccgt tggatacaat
     7141 aaaatgatcc agtctggata cggaagttgc cgctgccgta ggtcccttta catccttgcc
     7201 cgcagatggc gaaacgccgt ctgcaacagg tgtgtgtgca tatcttccat ccggcgtcgc
     7261 tcctgtctgt ccgcccaacg gtacatttgc agatacagga tacagacctg cctggaactt
     7321 tccgcctctt ggattgttat acttctgaag cggtttggaa tatgtatagg caacttctct
     7381 tgcaaaataa tcaacttccg gaatatcatt tccaaatttc ggaacttcat cgatcatatc
     7441 gtggatttct ttgaatctct gtgtcttctg ttcacccggt ttcattccca tgaaagtttt
     7501 cataagtcct tctgcagtgg aagcatccac atttctgcct gctttctgca ttgccttcat
     7561 gatcatctct gtcatatcac ctgcggactg cgcatccagt cctttatcat agttccatgc
     7621 aagagcttcc ttaagttctt tcatagatac tttcttatcc tcatagacca gtttgcggat
     7681 tgcaaaaagt ccatctgcca tattggcgat tccaaatccc tgaggacctg taaagttgta
     7741 aacagctcca ccttcctgga cagacttgcc ttctttcaga cagtcatcta tcatacagga
     7801 aaggaatggt aacggacagc gttccgcatg agctacatca atagcattat ctgcattcac
     7861 cagcagggaa atgcagtatt ccatctgttt cttatatgcg tcaaagaatt catcaaaggt
     7921 cttcatctga gtgacatcgc cggtagggat tcccaccatc tcacctttat ccataccatt
     7981 cgaaaaaaca agttccagag gtctgcacat attaaagaat gcggcatcat gccacccttc
     8041 tgtcttaccg gctttctgtg gttccacaca tccgatgata ttgtactctc tggcatcctc
     8101 cagagataag cctctgttct gcagtgccgg aataatcacc tcatcattgt aatatgcagg
     8161 aagtccgatt cctgttctcg taagctcggc tgcctttatc aggaattcat gcggagaacc
     8221 attccatact ctcacagaaa gtgatggagc cggaagatgc acatgcatgg atgcctgaat
     8281 acacataaca gaaagatcgt tagttacatc ctctccctct ttattctgac cacccgcaat
     8341 cagattctgg aaaaggctgt atcctgcaaa tccttccgct gaagccgcat cacgacattt
     8401 attcaagtca tttaatttaa cccagatgca atccatcaat tcctgtgcga actctcgggt
     8461 aatagttcct gcttccatat ccttcttata atatggatac atatactgat caaagcgacc
     8521 cggtgaaata gaatgtccac tggattccat ctgaagaagc tgctgtacaa accagaatga
     8581 ctgacatgcc tcatagaaat tctgtgcacc ctttgccggt accctgctgc agttctctgc
     8641 gataacaaaa agttcctgtt ttcttaccgg atcacttgtc tgtgccgcca tttcctgcgc
     8701 aagttttgca tatctgcctg cataatcgat caccgcctta cagcttaaaa tcactgcttc
     8761 aaggaagtga gactttcttg cataattacc gtcaccgaca ctgcatccat ccagctcttt
     8821 ctgagctttc tccatgattc cctcaaaacc ggtttccagt acttcccagt atttaactgt
     8881 tacatgtcct acaccattgt aaaaatagtt cccaggtgta aaaatattgt gttcaattgc
     8941 cttgattgct tccggtgcca tataggaagt tgcaagttca ctggttgttt tccctttcca
     9001 gtacttatct gcctccttaa gttcggcttt ggtctcctca gcaatctcaa aaggatccgc
     9061 agttctggtc gcaactgtat ccagttcagc ttccagccac tcataagaga actccggaaa
     9121 tgtctgacat cccctcggcg caatcgtact gcttccgaca atcagttcat tgtcacggat
     9181 aatgatcgga atattatgaa gaatatgcgc aaaagccttt gctctgcgtg tgatgatcgg
     9241 ttctccttct gtttccttat aagattctgt gatcagcttt gctctggctg attcgatcac
     9301 cggcatatgt tcatacaatg catctaccag tttctgaatt ctgggagact tgggaatatc
     9361 tgatgtttga aatttttcca tgttactcct ttctcatgaa taaaagctgc acccatacca
     9421 gaccccaata cattccggta tcattctgac agcaatatcc tccatgtttt catatagatt
     9481 cattatacct tatggctatt gcgaagtcaa cataaatcaa catgtatatt ctgaactttt
     9541 atgttgtttt ttatttgttt tttcttccgt tctggttgtt tttgttttgt ttttatgatt
     9601 gacatttcat ttttcttcag acacgttaaa agcagcatat caggttatga tccataactc
     9661 tgatatgctg ctttttaata tcgtatattg ttttttctgc atcggatgac tttaatgaga
     9721 atgcttttcc atcgctgcac tcccatatat tcatatacac ttaactattg tttcctgttc
     9781 tctttttgtt ctctggcttc tcttactttc tccctctgtt tcgtcagatc gtaataatca
     9841 tctgtaagaa ccccatgttt tcgcatcata tcaaacacag tctgctgagc aggtgtcatc
     9901 ttcatgccaa tagaattatt ataatccgta agaacgcatc ctgttttctc aatcagccag
     9961 aacagcggag aatcatcatc cgggatcatt ttccagattt cgttctctgt ccatggaagc
    10021 aattccatca ttccatgaag atgtcctctg ggtattctta cgtaatcgcc gtccggcttg
    10081 atcagaccgt cagaaaagtt ctcatcctta attttcatct catttaacag ttcttctgtt
    10141 atcttcatcc tcttttcctc accctcgagt attgcttttt cctattatac gtttcccgcc
    10201 agagttacgc aagtaaaaag tctgaatagc ctctttcctc aaaaatatat
//
