LOCUS       gnlProkkaBAEMBNGD_83    7550 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BAEMBNGD_83.
ACCESSION   gnlProkkaBAEMBNGD_83
VERSION     gnlProkkaBAEMBNGD_83
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 23:06:02
            Original ID  :: gnl|Prokka|BAEMBNGD_83
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7550
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..495
                     /locus_tag="ctg83_1"
                     /transl_table=11
                     /translation="MSIHFHVVVNMVVVLLVGLVLRLFPAFAMGNYIIKSTTASECITS
                     LSRMYIGRNITIPLSVLFRFLPTMQEESAAIKDAMRMREIQFGTKKFWQNPMALLEYRF
                     IPLMISVVKIGDELSAAALTRGLDNPAKRSSITKVGFTYYDAIALVISGIMLFITLFII
                     K"
     protocluster    1..7550
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2990:6134]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2991..6134
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..7550
                     /SMILES="NC(CS)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..7550
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             512..2011
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 154.1; E-value:
                     8.2e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg83_2"
                     /transl_table=11
                     /translation="MIEIKNVSFTYESGESENSLRNINLKIEDGETILLCGESGCGKTT
                     LTRLINGLIPHYYNGQLTGQIYLDGKEVKDYQLYQIASMVGSVFQNPRTQFYNVDTTSE
                     IVFGCENMGLSVQEMLARLENTTKRLKLENLLGRSLFALSGGEKQKIACASADAIYPNT
                     FVLDEPSSNLDISSIKDLTEVIRQWQSEKKTVIVAEHRLYYLAPYADRIIYMKRGEICN
                     EYTREEFLELDPKELKKMGLRALNPFDLMPEKKPEVNEKSLQIDNFWFSYEKRGYPIVN
                     IPNLTLPQGEIIGIIGDNGAGKSSFARCLCGLDKSSKGTLKLNGNSLNAKKRRHISYMV
                     MQDVNHQLFTEDVLDELLLSMDGENEEEDKVRAQEILAGLDLSDKLKLHPMSLSGGEKQ
                     RVAIGSAVASGKEIIIFDEPTSGLDYRHMLEVSEKLIQLKEMKKTLFLITHDPELIYKC
                     CTHLMFIEHGRILWHRPMDNEAVRLLQEFFSHEKGDSAMAI"
     CDS             2113..2259
                     /locus_tag="ctg83_3"
                     /transl_table=11
                     /translation="MIQAAVLFIIDGNVDLSKSLRQLFYKFVKKIFWEETYDHKKSVFS
                     ICV"
     CDS             2222..2986
                     /NRPS_PKS="Domain: Thioesterase (22-235). E-value: 7.7e-34.
                     Score: 109.9. Matches aSDomain:
                     nrpspksdomains_ctg83_4_Thioesterase.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004:thioesterase (Score: 190.4; E-value: 4.6e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg83_4"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7e-10, bitscore:
                     28.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIKNRYFPFVSENVADSNKGTILFCFHHAGGTATTYRPWTLKSN
                     DSVIIMCVELPGKGTRRTERMAVDFNEILPELSLQIADVSCGRKIVLYGHSMGAAMAFY
                     TAHYLWNQLDRKCEKVIVAGRQPPDQENPYEFKSYMNDDALIEELVRYNATPKEVLENK
                     ELLNFILPGLRQDYILNESLVYHGEVLDIPIVAHTGSQDYEANAEIMNLWKHMTTNIFQ
                     LNLFEGSHFFVTDLGNKYRDIVIQEAINKRED"
     aSDomain        2288..2926
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_4_Thioesterase.1"
                     /evalue="7.70E-34"
                     /label="ctg83_4_Thioesterase.1"
                     /locus_tag="ctg83_4"
                     /protein_end="235"
                     /protein_start="22"
                     /score="109.9"
                     /tool="antismash"
                     /translation="ILFCFHHAGGTATTYRPWTLKSNDSVIIMCVELPGKGTRRTERMA
                     VDFNEILPELSLQIADVSCGRKIVLYGHSMGAAMAFYTAHYLWNQLDRKCEKVIVAGRQ
                     PPDQENPYEFKSYMNDDALIEELVRYNATPKEVLENKELLNFILPGLRQDYILNESLVY
                     HGEVLDIPIVAHTGSQDYEANAEIMNLWKHMTTNIFQLNLFEGSHFFVTD"
     CDS_motif       2492..2548
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_4_0001"
                     /evalue="5.50E-05"
                     /label="NRPS-te1"
                     /locus_tag="ctg83_4"
                     /protein_end="109"
                     /protein_start="90"
                     /score="15.7"
                     /tool="antismash"
                     /translation="VLYGHSMGAAMAFYTAHYL"
     CDS             2991..6134
                     /NRPS_PKS="Domain: AMP-binding (152-550). E-value: 1e-87.
                     Score: 286.2. Matches aSDomain:
                     nrpspksdomains_ctg83_5_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1034). E-value: 9.4e-17. Score:
                     52.9. Matches aSDomain: nrpspksdomains_ctg83_5_PCP.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg83_5"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-96, bitscore:
                     311.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.9e-15, bitscore:
                     45.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKENISIIKGMDTLRTIAEERKVSVNVLLKGIAVEIYYRWFANET
                     AIEYVTLNDLISEVIDRSKDKDTIVINDYVCSVMCNNDKAVLCIECEQLECDMIEGLSA
                     FTEEFVLEWADLADNAPIVHQIPRNQMAVRKNRNRTKKTFSDECLHHGFFENAANAPGK
                     AALIYYKNGNKEEISYFCLQDMILKLAGYLKENGVKSGTLVGVSIPKGINQVIAVYGIL
                     AAGATYVPIGVHQPVERKKKIIDTGRIRYIVTSNEMGSEEDLGVSVICLEAVLQKALPA
                     KVPVFPETNQPAYIIFTSGTTGIPKGVVISHSEAHNTIADINQRFNIGRNHTGIAISDL
                     DFDLSVYDIFGLLSAGGTLVVLSEETKREPVFWRKAIIDAGVNVWNSVPALFDMLLTTC
                     ETDKQMLPLQLVLLSGDWIKMDLYDRLKAISECCKFVSLGGATEAAIWSNYFVVNDIDS
                     GWKSIPYGEPLSNQYLRVVDGNGYDCPDYVNGELWIGGDGVAEGYLNDPELTDAKFVAI
                     DGVRWYKTGDLVRYNSAGIVEFLGRIDNQVKINGYRIELGEVENVIKRSPDVSNVVVGV
                     VDEKGKKELGAVIVPKINAAVNVDITCCEDNNKYSDFHMKERERIVRQLILEFCHMQSR
                     VSAEYRPIMEFWEGWLESHMEYSADIFSAREEMEPLQKVMNARNLFAEILTGEQRVEEL
                     LRREEVSPEFWSLKGEDTKYFLDKILAGDISNRKIAVLGARTGEIIKQYWDGFCQAEEI
                     TLFDTSAGILKLAQEKLGGMNANIRYCSTYNEGVEESELNKYDIVLAVNLLHTYEEPLK
                     EVKWAALLLKRKGDFYAIEYEELDPMGILISGLLENGFVNRKRGRREHTPLLLLDDWKN
                     IYGQAPFGEVAINRRGRLGALLIHAKNVTPEVIEMRSRILEYMNENLTAYMIPTKRMIV
                     KQVVLSKNGKVNRQQSLALLAVKQTAEKESIILQGIEADIAELWTNILSCKIFDRSQSF
                     FESGGDSLSATRFLAEIKKKYSVDIPLKDIFSTPSLKSVADMLQARLTENEGMVEGEI"
     aSDomain        3447..4640
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_5_AMP-binding.1"
                     /evalue="1.00E-87"
                     /label="ctg83_5_AMP-binding.1"
                     /locus_tag="ctg83_5"
                     /protein_end="550"
                     /protein_start="152"
                     /score="286.2"
                     /specificity="substrate consensus: Cys"
                     /tool="antismash"
                     /translation="FFENAANAPGKAALIYYKNGNKEEISYFCLQDMILKLAGYLKENG
                     VKSGTLVGVSIPKGINQVIAVYGILAAGATYVPIGVHQPVERKKKIIDTGRIRYIVTSN
                     EMGSEEDLGVSVICLEAVLQKALPAKVPVFPETNQPAYIIFTSGTTGIPKGVVISHSEA
                     HNTIADINQRFNIGRNHTGIAISDLDFDLSVYDIFGLLSAGGTLVVLSEETKREPVFWR
                     KAIIDAGVNVWNSVPALFDMLLTTCETDKQMLPLQLVLLSGDWIKMDLYDRLKAISECC
                     KFVSLGGATEAAIWSNYFVVNDIDSGWKSIPYGEPLSNQYLRVVDGNGYDCPDYVNGEL
                     WIGGDGVAEGYLNDPELTDAKFVAIDGVRWYKTGDLVRYNSAGIVEFLGRIDNQVKIN"
     aSModule        3447..6092
                     /complete
                     /domains="nrpspksdomains_ctg83_5_AMP-binding.1"
                     /domains="nrpspksdomains_ctg83_5_PCP.1"
                     /locus_tags="ctg83_5"
                     /monomer_pairings="Cys -> Cys"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       3648..3683
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_5_0001"
                     /evalue="6.70E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg83_5"
                     /protein_end="231"
                     /protein_start="219"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GILAAGATYVPI"
     CDS_motif       3867..3926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_5_0002"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg83_5"
                     /protein_end="312"
                     /protein_start="292"
                     /score="30.1"
                     /tool="antismash"
                     /translation="AYIIFTSGTTGIPKGVVISH"
     CDS_motif       4041..4076
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_5_0003"
                     /evalue="5.40E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg83_5"
                     /protein_end="362"
                     /protein_start="350"
                     /score="-1.6"
                     /tool="antismash"
                     /translation="GLLSAGGTLVVL"
     CDS_motif       4443..4532
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_5_0004"
                     /evalue="2.50E-14"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg83_5"
                     /protein_end="514"
                     /protein_start="484"
                     /score="45.4"
                     /tool="antismash"
                     /translation="PDYVNGELWIGGDGVAEGYLNDPELTDAKF"
     CDS_motif       4605..4670
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_5_0005"
                     /evalue="6.50E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg83_5"
                     /protein_end="560"
                     /protein_start="538"
                     /score="37.4"
                     /tool="antismash"
                     /translation="FLGRIDNQVKINGYRIELGEVE"
     aSDomain        5889..6092
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_5_PCP.1"
                     /evalue="9.40E-17"
                     /label="ctg83_5_PCP.1"
                     /locus_tag="ctg83_5"
                     /protein_end="1034"
                     /protein_start="966"
                     /score="52.9"
                     /tool="antismash"
                     /translation="EADIAELWTNILSCKIFDRSQSFFESGGDSLSATRFLAEIKKKYS
                     VDIPLKDIFSTPSLKSVADMLQA"
     CDS             6159..7550
                     /NRPS_PKS="Domain: Heterocyclization (71-358). E-value:
                     3e-73. Score: 238.7. Matches aSDomain:
                     nrpspksdomains_ctg83_6_Heterocyclization.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127:condensation domain-containing protein (Score:
                     88.4; E-value: 1e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg83_6"
                     /sec_met_domain="Condensation (E-value: 1.3e-41, bitscore:
                     131.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTKEFIWLADNELRINLNKLASDGINVWLEDEKLKFKGEQGKV
                     TEEVLKWMRQNKTAIISYLLEKEEVQDKGFDLTPIQKAYFLGRDNLYELGGISANYYFE
                     IDMDKLDVKKFESIFNQVIHDNEALRGIILKCGRQAVLSNVPWFSIEVKRVNDEAEQKA
                     LRSEWESKIYPLESWPMFHVCLTTKDNCCYRLHVGFDCILLDAWSVTLMLKQIYKLYEN
                     DKIMVPAYTFREYCNEHGKLLNEKLKEQAERYWSQRCEMLPKAPALPYAKKLSEINIPH
                     FRRLNYELPKFDTETIYMKAKEYKVTPAAVLCTVYMKVLAEYAESPEFSINLTVFNRLS
                     ANREVQEVLGDFTNISIAVYEAKKGRPFKEEVLETQKEFWNLVKYRGYEGVKIIRKMPK
                     DNPVQASLPVVFTGILQGLKQADYYLPNWAREIYAYSQTPQVSLDYQATDFKGNLSVNW
                     DYVVQA"
     aSDomain        6372..7232
                     /aSDomain="Heterocyclization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg83_6_Heterocyclization.1"
                     /evalue="3.00E-73"
                     /label="ctg83_6_Heterocyclization.1"
                     /locus_tag="ctg83_6"
                     /protein_end="358"
                     /protein_start="71"
                     /score="238.7"
                     /tool="antismash"
                     /translation="DKGFDLTPIQKAYFLGRDNLYELGGISANYYFEIDMDKLDVKKFE
                     SIFNQVIHDNEALRGIILKCGRQAVLSNVPWFSIEVKRVNDEAEQKALRSEWESKIYPL
                     ESWPMFHVCLTTKDNCCYRLHVGFDCILLDAWSVTLMLKQIYKLYENDKIMVPAYTFRE
                     YCNEHGKLLNEKLKEQAERYWSQRCEMLPKAPALPYAKKLSEINIPHFRRLNYELPKFD
                     TETIYMKAKEYKVTPAAVLCTVYMKVLAEYAESPEFSINLTVFNRLSANREVQEVLGDF
                     TNISIA"
     CDS_motif       6738..6782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0001"
                     /evalue="1.40E-04"
                     /label="Cy3"
                     /locus_tag="ctg83_6"
                     /protein_end="208"
                     /protein_start="193"
                     /score="15.0"
                     /tool="antismash"
                     /translation="RLHVGFDCILLDAWS"
     CDS_motif       6987..7013
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0002"
                     /evalue="2.00E+00"
                     /label="afterCy4"
                     /locus_tag="ctg83_6"
                     /protein_end="285"
                     /protein_start="276"
                     /score="2.0"
                     /tool="antismash"
                     /translation="INIPHFRRL"
     CDS_motif       7074..7121
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0003"
                     /evalue="5.60E-06"
                     /label="Cy4"
                     /locus_tag="ctg83_6"
                     /protein_end="321"
                     /protein_start="305"
                     /score="19.2"
                     /tool="antismash"
                     /translation="VTPAAVLCTVYMKVLA"
     CDS_motif       7143..7175
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0004"
                     /evalue="6.50E-04"
                     /label="afterCy4"
                     /locus_tag="ctg83_6"
                     /protein_end="339"
                     /protein_start="328"
                     /score="12.4"
                     /tool="antismash"
                     /translation="FSINLTVFNRL"
     CDS_motif       7188..7226
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0005"
                     /evalue="7.90E-04"
                     /label="Cy5"
                     /locus_tag="ctg83_6"
                     /protein_end="356"
                     /protein_start="343"
                     /score="12.0"
                     /tool="antismash"
                     /translation="EVQEVLGDFTNIS"
     CDS_motif       7464..7502
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg83_6_0006"
                     /evalue="2.10E-05"
                     /label="Cy7"
                     /locus_tag="ctg83_6"
                     /protein_end="448"
                     /protein_start="435"
                     /score="17.5"
                     /tool="antismash"
                     /translation="SQTPQVSLDYQAT"
ORIGIN
        1 aactcaattc attttcatgt ggttgtcaat atggttgtag ttttattggt gggattggtt
       61 ttaagacttt ttcctgcttt tgcaatggga aattacataa ttaaatctac tactgccagc
      121 gagtgtatta catcgctgag cagaatgtat atcggtagga acattaccat tcccctttct
      181 gtgctatttc gttttttgcc taccatgcaa gaagagtcag cagctattaa agacgctatg
      241 agaatgaggg aaatccagtt tggtacgaaa aaattttggc aaaatccaat ggctctgctt
      301 gaatatcgtt tcataccgct tatgatttcg gttgtaaaga ttggtgatga gctgtctgca
      361 gcagcactaa cccgtgggtt ggataatcca gcaaagcggt caagtataac gaaagttgga
      421 tttacctatt atgatgccat tgcgttggtg atttcaggca ttatgctgtt tattacctta
      481 tttattatta aatagtagaa gaggaattga aatgatagaa attaaaaatg tgtcctttac
      541 ctatgaaagt ggggaatcag agaatagcct gcgtaatatc aatctgaaaa ttgaagatgg
      601 agagactatt ttactatgcg gtgaatctgg ttgcggtaaa acaactttga cacgtctgat
      661 taatggactg attccgcatt attataatgg acagttaact ggacagattt acttggatgg
      721 gaaagaggta aaggattatc agttatatca gattgcctcc atggttggct ctgtatttca
      781 aaatccaaga acacagtttt acaatgtaga tacgacaagc gagattgtgt ttggatgtga
      841 aaatatggga ttgtcggtgc aggaaatgct ggcaaggctt gagaatacaa caaaacgcct
      901 taaattagag aatctgcttg gacggagcct gtttgcttta tcgggtggag aaaagcagaa
      961 aatagcttgt gcatcggcag atgctatcta ccctaatact tttgttttag atgaaccgtc
     1021 ttctaatttg gatatttctt cgataaaaga tttaacagaa gtaattcgcc aatggcaatc
     1081 tgaaaagaag acagtaatcg ttgccgaaca ccgcctgtat tacctggctc catatgcgga
     1141 ccgaatcata tatatgaagc gcggagagat atgtaatgaa tatacaagag aggaattttt
     1201 ggaactagat ccaaaggagt taaagaaaat gggattacgt gcattaaatc catttgactt
     1261 gatgcctgaa aaaaaacctg aagtaaatga aaaaagcctg cagattgata acttttggtt
     1321 ttcatatgaa aaacggggat atccgattgt aaacataccg aatttaacat tgccgcaggg
     1381 agaaatcatt ggaatcattg gtgacaatgg agctggtaaa tcctcttttg ccagatgtct
     1441 atgcggatta gataaatctt caaagggcac tttgaaatta aatggcaatt cccttaatgc
     1501 gaagaagcgc cggcatattt cctatatggt aatgcaggat gtaaatcacc agctttttac
     1561 agaagatgta cttgatgaac ttttgctgag tatggatgga gaaaatgagg aagaggacaa
     1621 ggttcgggca caagaaattt tggctgggct tgatttgtcg gataaactga aactgcaccc
     1681 aatgtcgtta tccggtggtg aaaagcagcg agtcgctatt ggcagtgctg ttgcatctgg
     1741 gaaagaaata atcatatttg atgaacccac cagcggattg gattatagac atatgcttga
     1801 ggtttcagaa aaattaatac agctaaaaga aatgaaaaaa acgttgtttc ttataacgca
     1861 tgatcctgaa ctgatataca aatgctgtac acatcttatg tttattgagc atggccgtat
     1921 attatggcat cggcctatgg ataacgaggc tgtaagactt ttacaggaat ttttctccca
     1981 cgaaaagggt gattcagcaa tggctatatg aaagcgaaag agtactttga agtgggctga
     2041 gagaaatata aggactaaag agaacttatt tcggatatag aaatatgtaa gagtaagctg
     2101 gaagttaata taatgattca ggccgcagta ctttttataa tagatggcaa tgtcgattta
     2161 tcaaaaagtc tgcggcaatt attttataaa tttgttaaaa agatattttg ggaggaaacg
     2221 tatgaccata aaaaatcggt attttccatt tgtgtctgaa aatgtagctg acagtaataa
     2281 ggggactatc ctgttttgct ttcatcatgc aggaggaaca gcaacaacat atcggccgtg
     2341 gactttgaaa tctaatgatt cagtgattat tatgtgtgtc gagctgcctg gaaagggaac
     2401 caggcggact gaaagaatgg ctgttgattt caatgagatt ctgccggaac tgtcattgca
     2461 aattgctgat gttagctgtg gcagaaagat tgttctgtat gggcacagta tgggggcagc
     2521 aatggcgttt tatacggcac attatttatg gaatcaatta gacagaaaat gtgaaaaagt
     2581 aattgttgcc gggcgtcagc ctccggatca ggaaaatccc tatgaattta agtcctatat
     2641 gaatgacgat gctttaattg aggagttagt tcggtataat gccacaccaa aggaagtgct
     2701 agaaaataaa gagctgctga attttattct tccgggtctg cgtcaggatt atatattaaa
     2761 tgaaagtctg gtttatcatg gagaagtgtt ggatataccg atagtagcgc ataccggaag
     2821 ccaggattac gaggcaaatg cagagataat gaatttgtgg aaacatatga caaccaatat
     2881 ctttcagttg aatttgttcg agggttccca tttctttgtt acggatttag gcaataagta
     2941 tagggatatt gtgatacagg aagcaattaa taaacgggag gattaagcct atgaaggaga
     3001 acatttcgat tataaaagga atggacacgt taagaacaat tgcagaggaa cggaaggtat
     3061 cggttaatgt actgctaaag ggaatcgcag tggaaatata ttatcgttgg tttgcaaatg
     3121 aaacagcaat agaatatgtg acgctgaatg atttgattag tgaggtaatc gacaggtcca
     3181 aggataaaga taccatagtt atcaatgatt acgtgtgcag tgtaatgtgc aacaatgata
     3241 aggctgttct gtgcattgag tgtgagcagt tggaatgtga tatgatagaa ggcttgagcg
     3301 cttttactga ggaatttgtt ttggagtggg cagatttagc tgataatgct ccaattgtcc
     3361 accaaattcc gagaaatcag atggctgtca ggaagaatag aaataggacg aaaaaaacat
     3421 tttcagatga atgcctacat catggatttt ttgaaaatgc ggcaaatgcg cctgggaaag
     3481 cagcgcttat atattacaag aatggaaata aagaagaaat tagttatttc tgcttacagg
     3541 atatgatttt aaagttagct ggatatttaa aggaaaatgg tgtaaaaagc ggaacgctgg
     3601 tcggtgtaag tatacccaaa ggcattaatc aggttattgc cgtttatggt attttggctg
     3661 caggagcaac atatgtgcct attggtgttc accagcctgt agaaagaaaa aagaaaatta
     3721 tagatactgg aagaataagg tatatcgtaa caagcaatga aatggggtca gaagaagatt
     3781 taggagtatc tgtgatctgc cttgaagcgg ttcttcagaa agcgttaccg gcaaaagtac
     3841 ctgtctttcc cgaaacgaac caaccggctt atattatttt tacatcgggt acaactggta
     3901 tacctaaagg tgtggttatc tcccatagtg aggcccataa tacaatagct gatataaatc
     3961 aacgatttaa tataggcagg aatcatactg ggatcgctat ttcagacttg gattttgatt
     4021 tatctgttta tgatattttt ggattgttat cagctggggg aaccttggtg gtattgagtg
     4081 aggaaacaaa aagggagcct gtcttttgga gaaaagcaat tattgatgca ggcgtaaatg
     4141 tttggaactc ggttccggca ttgtttgata tgttattaac cacctgtgaa actgataaac
     4201 aaatgctgcc gcttcaactg gttttattat ccggagattg gattaagatg gatttatatg
     4261 acaggctgaa agcaatcagt gaatgctgta agtttgtttc tctgggagga gcaacggaag
     4321 cggccatatg gtctaattat tttgttgtga acgatattga cagcggctgg aagtcaatac
     4381 catatggtga acccctgagc aatcagtatc tgagagttgt tgatggtaat ggatatgatt
     4441 gtccggatta tgtaaatggg gaactgtgga ttggcggaga cggtgtagca gaaggctact
     4501 taaatgaccc tgaattaaca gatgcgaagt ttgttgcaat agatggggta aggtggtata
     4561 aaaccggcga tttggtccgg tataattctg cagggattgt agaatttctg ggtagaatcg
     4621 acaatcaggt taagattaat ggctaccgaa tcgaattggg agaagtagaa aatgttatta
     4681 agcgttctcc ggacgtttct aatgtagtgg taggtgtggt tgatgagaaa ggaaaaaagg
     4741 aattaggagc tgtgattgtt ccgaagataa atgctgctgt caatgtagat attacttgtt
     4801 gtgaggataa caacaagtat tcggatttcc atatgaagga acgtgaaaga attgtcaggc
     4861 agttgattct tgaattctgt catatgcaat caagggtatc agcagagtat aggccgatta
     4921 tggaattttg ggagggctgg cttgaatccc atatggaata ttcagcagat atattttccg
     4981 ccagagagga aatggaacca ttgcaaaagg ttatgaatgc aaggaatctt tttgcggaga
     5041 tactcacggg tgagcaacgt gtggaggagc tgcttcggag ggaggaggtt tcaccagagt
     5101 tctggtcttt aaagggagaa gatacgaagt actttttaga caagatactg gcaggcgata
     5161 taagtaacag gaaaatcgca gttttgggtg caagaacagg agaaattata aagcaatact
     5221 gggacggatt ctgccaggca gaggagataa cgttatttga tacttcagcg ggaatattga
     5281 agttggcaca ggaaaaactg ggaggaatga atgcaaatat ccgctattgc agtacataca
     5341 atgagggtgt ggaagaatcg gaactgaata aatatgatat tgttttggcg gtaaatctat
     5401 tgcataccta tgaggaacct ttaaaggaag tgaagtgggc agcgcttctg ctgaagagga
     5461 aaggggactt ttatgcaatc gagtatgagg agttagaccc tatgggtatt cttatttctg
     5521 gattgctgga gaatggattt gttaacagaa agcggggaag acgagagcat acgcctttac
     5581 tattattgga tgattggaaa aatatttatg gacaggctcc ttttggtgag gttgcaataa
     5641 acagaagagg aagattggga gctctgttaa tccacgctaa aaacgtaaca ccagaagtaa
     5701 tagaaatgag atctcgtata ttagaataca tgaatgaaaa tctgacagcc tacatgattc
     5761 cgactaaacg catgattgta aagcaagtag tattgagcaa aaatggaaaa gtgaatagac
     5821 agcagtcatt agcgttattg gctgtaaaac aaacagcgga aaaggagagt atcatacttc
     5881 agggaattga agctgatatt gcagagcttt ggacaaacat tctgagttgc aaaatatttg
     5941 ataggagcca gagctttttt gaatcgggcg gagatagtct atcagcaact cggttcctgg
     6001 cggaaatcaa gaagaaatac tctgtggata taccattaaa ggatatcttt agcacgccat
     6061 ctctcaagtc tgttgcggat atgcttcagg ccaggcttac ggagaatgaa ggtatggttg
     6121 aaggcgagat ataaaactct ggaaggagcg ttgactctat ggataaaaca aaagagttca
     6181 tatggctggc agataatgag ttgagaataa atttaaataa attagccagt gatggaatca
     6241 atgtatggtt agaggatgaa aagctaaagt ttaaaggcga acagggcaag gttacggaag
     6301 aggtattaaa atggatgcgg cagaataaaa cagcaattat atcctatctc ttggagaagg
     6361 aggaggttca ggataaggga tttgatttaa ccccgataca aaaggcgtat ttcttgggta
     6421 gggataacct ctatgaattg ggaggtatca gtgctaatta ctattttgaa atagatatgg
     6481 ataagctgga tgttaagaaa tttgaatcaa tatttaacca ggtgattcat gataatgagg
     6541 cactgagagg cattatcttg aagtgtggga ggcaggctgt tttaagtaac gtaccgtggt
     6601 tctccattga agtgaaaaga gtaaatgatg aagcagagca aaaagcgctg cggtcggagt
     6661 gggaaagcaa aatatatccg ttggagtctt ggcctatgtt tcatgtgtgt ctgacaacaa
     6721 aggataattg ctgttacagg ctgcatgtgg ggtttgactg tattttgctg gatgcctgga
     6781 gtgtcacact tatgctgaag cagatatata aactttatga aaatgataag attatggttc
     6841 ctgcatacac ctttagagaa tattgcaatg aacatgggaa gcttctgaat gaaaaactta
     6901 aggagcaggc tgagcggtat tggagccagc ggtgtgaaat gcttccgaag gcaccggcct
     6961 tgccatatgc aaaaaaacta tcggaaatta atataccgca ttttagaaga ttgaattatg
     7021 agttaccgaa attcgataca gaaacaatat atatgaaggc aaaggaatac aaagtaaccc
     7081 cggcagcagt cctgtgtact gtttatatga aagtattggc agaatatgcg gagtctcctg
     7141 agttttccat aaatctaacc gtgtttaatc gtttatcagc aaatagggaa gtgcaggaag
     7201 ttcttggaga ctttacgaat atcagtatcg cggtatatga agcgaagaaa ggacggccat
     7261 ttaaggagga ggttctggaa acacagaaag aattttggaa tttggttaaa tacagagggt
     7321 atgagggcgt aaagataatc agaaaaatgc caaaggataa tccagttcaa gcgtctttgc
     7381 cagtggtttt tacgggaatc cttcagggac ttaaacaggc cgattactat ctccccaatt
     7441 gggcaagaga aatttatgcc tacagccaga cacctcaagt ttctttggat tatcaggcaa
     7501 cggattttaa aggtaatctg tctgttaatt gggattacgt ggtacaggca
//
