LOCUS       gnlProkkaHDAEJHAN_137   6094 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDAEJHAN_137.
ACCESSION   gnlProkkaHDAEJHAN_137
VERSION     gnlProkkaHDAEJHAN_137
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:09:56
            Original ID  :: gnl|Prokka|HDAEJHAN_137
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6094
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6094
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[803:6092]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      804..6092
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..6094
                     /SMILES="NC([*])C(=O)NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6094
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             2..790
                     /locus_tag="ctg137_1"
                     /transl_table=11
                     /translation="MYILLAVIFVLIMLFTEEITVMFGSGGGELGSHMVQALRIFALCV
                     APYLWNKFIISYYESIEETAIASFATFLENAVVVLPATLVGILVWKQIDGIGIDGIAAG
                     FVATEIITAVAACIFRKIRHKNTSFYIVPDKNPGINLDFSIKSTMEEAQTVHKRIIEFC
                     QEQGASKSKANLAAVCAEEMTVNIIRFGGKTSNWIDINLCLEDDLCRLRIRDNGVNFNP
                     LEYQYDSEDFDIHGIELVKKVSKSMDYIRAIDMNNTIISF"
     CDS             804..6092
                     /NRPS_PKS="Domain: AMP-binding (20-419). E-value: 1.6e-104.
                     Score: 341.6. Matches aSDomain:
                     nrpspksdomains_ctg137_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (521-585). E-value: 7.2e-12.
                     Score: 37.6. Matches aSDomain:
                     nrpspksdomains_ctg137_2_PP-binding.1"
                     /NRPS_PKS="Domain: Condensation_LCL (597-878). E-value:
                     3.4e-38. Score: 123.2. Matches aSDomain:
                     nrpspksdomains_ctg137_2_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1033-1421). E-value:
                     1.9e-91. Score: 298.5. Matches aSDomain:
                     nrpspksdomains_ctg137_2_AMP-binding.2"
                     /NRPS_PKS="Domain: PP-binding (1530-1591). E-value:
                     9.6e-11. Score: 34.0. Matches aSDomain:
                     nrpspksdomains_ctg137_2_PP-binding.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     294.7; E-value: 1.8e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_2"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-109, bitscore:
                     352.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.6e-13, bitscore:
                     37.6, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 3.6e-49, bitscore:
                     154.5, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNINERNNFVFEFRPVTELFEEQVKLHPEKCAVVSGKESFTYAQ
                     LNERANRIANALVEKGVRRETIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDDRI
                     RYIFEDSGAPFIITTKEIAEERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDLCY
                     CIYTSGSTGKPKGVLIEHINLANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEE
                     FLPLTNGMTAVIASDEEILNPLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQI
                     KVFDVGAEAFPPALYDKIRRVNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGN
                     VKVYIVDKENKILPDGETGELVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLAR
                     ISSEGEIEFFGRIDNQIKLRGLRIELGEIEEVINSYEGIITSITLPVDNKFLCCYFMAD
                     RQINTEELSAYASESLAHYMVPEVFVQLEKMPVTQNGKIDKKALPKPVAQPKNLKEPQT
                     PMQKKIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVTVKTSDIHENN
                     TVEKLEKYVMLAPKIRTYEKREVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVD
                     VQKLSDAISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKIKDELV
                     RPFKLEKGRLFRAGIYVIEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESY
                     TGFDAALDEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSMPVDTR
                     ESLVLSACEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVK
                     TLPVYCSCDPKVTIQAYMTELSEQILSSMANDIFPFSDICAKYGINSDLVFAYQAELGD
                     DFPIGDTVARGHDLSPDMSKMPLLIQVREYDHKYVLTAEYRSDMYSEAFVRGMLESYEA
                     AMDSLLKAKYISEVSVLSQNGADTIAEFNNTACEYDRSKTIADMFEELVQTIPDHTAVV
                     FKDKKYTYRELDEISDRLGKYIASQGIGSEDVVSILIPRCEYMAIAPMGVIKAGAAYQP
                     LDPTYPRDRLMYMMEDSSAKLLIADRELLPLVDGYKGPVLFTDQIWQLEDRDVVLEKPQ
                     LHDLFILLYTSGSTGVPKGCMLEYGNITAFCHWFKRYYGIDSDSRIAAYASFGFDACMM
                     DIYGAITNGAQLHIIPEEIRLDFIGLQRYFEENGITHSFMTTQVGRQFALEMDCKSLRY
                     LSVGGEKLVPCEPPKDYKFINAYGPTEATIFTTVFEVDKYYPNVPIGKALDNVKLYITD
                     KLGHMLPPGACGELMITGWQVSRGYLNKPEKTAEVYTKNLYDDTPGYEVMYHSGDVARF
                     LPDGNIQIIGRKDSQVKIRGFRIELSEVEEVIRRYEGIRDATVVAFDDPNGGKYIAAYV
                     VSDSTVDINALNDFIKETKPAYMVPAVTMQIDKIPLNQNQKVNKKALPLPEKKAAEIIK
                     PENEVQQILFDCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKTSDIK
                     NHPTIRMMEEFVKTAGKESKREVQESYPLTNTQEGIFIECTANMGSTIYNIPYLLKLDN
                     KVDLDRLAEAIDSTVEAHPYLKTRLFMDDNGNVLQKRNDGLSYKTPILNGMNRDTLVRP
                     YMLFNEQLFRFEIYRTCDGNYLFLDLHHIVADGTSLAIIINDINRAYSGEKLEPEGYTS
                     YDLALDN"
     aSDomain        864..2060
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg137_2_AMP-binding.1"
                     /evalue="1.60E-104"
                     /label="ctg137_2_AMP-binding.1"
                     /locus_tag="ctg137_2"
                     /protein_end="419"
                     /protein_start="20"
                     /score="341.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEEQVKLHPEKCAVVSGKESFTYAQLNERANRIANALVEKGVRRE
                     TIVGVVLERCCDFYAVRQGILKAGGAFAVATPDYPDDRIRYIFEDSGAPFIITTKEIAE
                     ERRELFAKLPCTVLLIEELLENENTENPQVKIGEHDLCYCIYTSGSTGKPKGVLIEHIN
                     LANFVNPDPKNAETYGYVSRGSVSLSMAAMTFDVSVLEEFLPLTNGMTAVIASDEEILN
                     PLMLGELIVRNKVDIMTTTPTYLSNMIDLPQLEKAVSQIKVFDVGAEAFPPALYDKIRR
                     VNPDAYIMNGYGPTETTISCTMKVITDSRNITIGTPNGNVKVYIVDKENKILPDGETGE
                     LVIAGLGVGRGYMNLPDKTEAVFIDLNGERAYKTGDLARISSEGEIEFFGRIDNQIKLR
                     "
     aSModule        864..2558
                     /complete
                     /domains="nrpspksdomains_ctg137_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg137_2_PP-binding.1"
                     /locus_tags="ctg137_2"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       1053..1079
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0001"
                     /evalue="4.60E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg137_2"
                     /protein_end="92"
                     /protein_start="83"
                     /score="4.7"
                     /tool="antismash"
                     /translation="GILKAGGAF"
     CDS_motif       1287..1346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0002"
                     /evalue="9.40E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg137_2"
                     /protein_end="181"
                     /protein_start="161"
                     /score="30.4"
                     /tool="antismash"
                     /translation="CYCIYTSGSTGKPKGVLIEH"
     CDS_motif       1737..1766
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0003"
                     /evalue="1.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg137_2"
                     /protein_end="321"
                     /protein_start="311"
                     /score="8.1"
                     /tool="antismash"
                     /translation="YGPTETTISC"
     CDS_motif       1863..1952
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0004"
                     /evalue="1.60E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg137_2"
                     /protein_end="383"
                     /protein_start="353"
                     /score="36.4"
                     /tool="antismash"
                     /translation="PDGETGELVIAGLGVGRGYMNLPDKTEAVF"
     CDS_motif       2025..2090
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0005"
                     /evalue="3.30E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg137_2"
                     /protein_end="429"
                     /protein_start="407"
                     /score="32.1"
                     /tool="antismash"
                     /translation="FFGRIDNQIKLRGLRIELGEIE"
     aSDomain        2367..2558
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg137_2_PP-binding.1"
                     /evalue="7.20E-12"
                     /label="ctg137_2_PP-binding.1"
                     /locus_tag="ctg137_2"
                     /protein_end="585"
                     /protein_start="521"
                     /score="37.6"
                     /tool="antismash"
                     /translation="KIFEIVADVVENDFFGTDTSFYRAGLSSISAMKLCILISEEFGVT
                     VKTSDIHENNTVEKLEKYV"
     aSDomain        2595..3437
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg137_2_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.40E-38"
                     /label="ctg137_2_Condensation_LCL.1"
                     /locus_tag="ctg137_2"
                     /protein_end="878"
                     /protein_start="597"
                     /score="123.2"
                     /tool="antismash"
                     /translation="EVYPLTGSQKGIFAECMKNPESTVYNIPFLFELESSVDVQKLSDA
                     ISQMIAAHPYLLTKVYLSDSGEMVQKPCEEAFVPEVVRTTNEQFEKIKDELVRPFKLEK
                     GRLFRAGIYVIEDRKYLFTDFHHILADGNSYDIIFEDIDRAYLGEKLEKESYTGFDAAL
                     DEEQQMKEGKYKKAEKYYDSIFEGIETESLPLPDCSGKTPERGYLSMPVDTRESLVLSA
                     CEKLGVTPNILFTGVFGILMSRYSNSEESLFATIYNGRNDSRLENTVCMLVKTLPVYCS
                     "
     aSModule        2595..5576
                     /complete
                     /domains="nrpspksdomains_ctg137_2_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg137_2_AMP-binding.2"
                     /domains="nrpspksdomains_ctg137_2_PP-binding.2"
                     /locus_tags="ctg137_2"
                     /monomer_pairings="X -> X"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2661..2756
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0006"
                     /evalue="5.20E-06"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg137_2"
                     /protein_end="651"
                     /protein_start="619"
                     /score="18.9"
                     /tool="antismash"
                     /translation="TVYNIPFLFELESSVDVQKLSDAISQMIAAHP"
     CDS_motif       2967..3032
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0007"
                     /evalue="1.70E-04"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg137_2"
                     /protein_end="743"
                     /protein_start="721"
                     /score="14.3"
                     /tool="antismash"
                     /translation="FHHILADGNSYDIIFEDIDRAY"
     aSDomain        3903..5066
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg137_2_AMP-binding.2"
                     /evalue="1.90E-91"
                     /label="ctg137_2_AMP-binding.2"
                     /locus_tag="ctg137_2"
                     /protein_end="1421"
                     /protein_start="1033"
                     /score="298.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEELVQTIPDHTAVVFKDKKYTYRELDEISDRLGKYIASQGIGSE
                     DVVSILIPRCEYMAIAPMGVIKAGAAYQPLDPTYPRDRLMYMMEDSSAKLLIADRELLP
                     LVDGYKGPVLFTDQIWQLEDRDVVLEKPQLHDLFILLYTSGSTGVPKGCMLEYGNITAF
                     CHWFKRYYGIDSDSRIAAYASFGFDACMMDIYGAITNGAQLHIIPEEIRLDFIGLQRYF
                     EENGITHSFMTTQVGRQFALEMDCKSLRYLSVGGEKLVPCEPPKDYKFINAYGPTEATI
                     FTTVFEVDKYYPNVPIGKALDNVKLYITDKLGHMLPPGACGELMITGWQVSRGYLNKPE
                     KTAEVYTKNLYDDTPGYEVMYHSGDVARFLPDGNIQIIGRKDSQVKIR"
     CDS_motif       4089..4130
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0008"
                     /evalue="3.20E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg137_2"
                     /protein_end="1109"
                     /protein_start="1095"
                     /score="14.1"
                     /tool="antismash"
                     /translation="MGVIKAGAAYQPLD"
     CDS_motif       4320..4370
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0009"
                     /evalue="7.90E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg137_2"
                     /protein_end="1189"
                     /protein_start="1172"
                     /score="21.6"
                     /tool="antismash"
                     /translation="LLYTSGSTGVPKGCMLE"
     CDS_motif       4722..4748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0010"
                     /evalue="4.40E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg137_2"
                     /protein_end="1315"
                     /protein_start="1306"
                     /score="6.9"
                     /tool="antismash"
                     /translation="YGPTEATIF"
     CDS_motif       4851..4937
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0011"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg137_2"
                     /protein_end="1378"
                     /protein_start="1349"
                     /score="40.0"
                     /tool="antismash"
                     /translation="PPGACGELMITGWQVSRGYLNKPEKTAEV"
     CDS_motif       5034..5096
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0012"
                     /evalue="8.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg137_2"
                     /protein_end="1431"
                     /protein_start="1410"
                     /score="33.8"
                     /tool="antismash"
                     /translation="IGRKDSQVKIRGFRIELSEVE"
     aSDomain        5394..5576
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg137_2_PP-binding.2"
                     /evalue="9.60E-11"
                     /label="ctg137_2_PP-binding.2"
                     /locus_tag="ctg137_2"
                     /protein_end="1591"
                     /protein_start="1530"
                     /score="34.0"
                     /tool="antismash"
                     /translation="DCIAEVLGYTDFGITTDIYEAGLTSITAIKLNILISKAFDIVIKT
                     SDIKNHPTIRMMEEFV"
     CDS_motif       5679..5789
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0013"
                     /evalue="1.40E-07"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg137_2"
                     /protein_end="1662"
                     /protein_start="1625"
                     /score="23.9"
                     /tool="antismash"
                     /translation="TIYNIPYLLKLDNKVDLDRLAEAIDSTVEAHPYLKTR"
     CDS_motif       5970..6035
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg137_2_0014"
                     /evalue="8.90E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg137_2"
                     /protein_end="1744"
                     /protein_start="1722"
                     /score="24.7"
                     /tool="antismash"
                     /translation="LHHIVADGTSLAIIINDINRAY"
ORIGIN
        1 cagttacatc ctgctggctg tgatctttgt ccttattatg ctgtttaccg aggaaatcac
       61 tgtcatgttc ggaagcggcg gtggcgagct gggcagccat atggtccagg cgctgcgcat
      121 ctttgctttg tgtgtggcac cttatctgtg gaataagttt attatcagct attacgagtc
      181 cattgaggag acagccattg caagttttgc cacatttctg gagaatgcgg tggtagttct
      241 gcctgcaacc ctggtgggaa tccttgtatg gaaacagatt gacgggatcg gcatcgacgg
      301 aattgcagca ggatttgttg ccactgagat cataactgca gttgcagcct gtattttcag
      361 aaaaatcagg cataagaata caagctttta tattgttcct gacaaaaatc cggggattaa
      421 tctggatttt tccattaaga gtaccatgga ggaagcacaa acggttcata agaggatcat
      481 agagttctgc caggaacagg gagcttctaa aagcaaggca aatcttgccg cagtgtgtgc
      541 ggaggaaatg actgtaaata ttatacgatt cgggggaaaa acctccaact ggatcgacat
      601 taacctctgt ctggaggatg atctctgcag actgaggatc agagataacg gtgtaaattt
      661 caaccctctg gaatatcagt atgacagtga agactttgat atacatggga ttgaacttgt
      721 caagaaggta tcaaaatcca tggattatat tcgtgcgatt gatatgaata ataccataat
      781 atctttttag gaggtacatg aaaatgaaaa atattaatga aaggaacaat tttgtttttg
      841 agtttcggcc ggtaacagaa ttgttcgagg aacaggtgaa gcttcatcca gagaaatgtg
      901 cagttgtctc cggcaaagag agcttcacct atgcacagct caacgaacgg gctaacagga
      961 ttgccaatgc acttgtggaa aaaggtgtca gacgggagac catcgtaggt gtggttcttg
     1021 agagatgctg tgatttctat gcagtgcgac agggtatcct gaaggcagga ggcgcatttg
     1081 cagttgccac accggattat cctgatgaca ggatccggta tatttttgag gattcaggag
     1141 ctccttttat tatcacaaca aaggagatcg cagaggaacg aagggaactg tttgctaagc
     1201 ttccctgtac agtacttctg atcgaggaac ttctggagaa tgagaataca gagaatcctc
     1261 aggtaaagat cggggagcat gatctttgtt attgtatcta tacttctggt tccacaggca
     1321 agcccaaggg tgtgctgatc gaacatatca accttgccaa ttttgtaaat ccggatccga
     1381 aaaatgcgga aacttatggt tatgtcagca ggggatcggt ttctctttcc atggcagcca
     1441 tgacctttga tgtgtctgtt ctggaggaat ttctgccact taccaacggg atgactgcgg
     1501 tgatcgcctc tgatgaggag attctgaatc ctcttatgct gggtgagctg atcgtcagaa
     1561 ataaagtgga tattatgacc acaactccta cttacctgtc caatatgatc gatctgcccc
     1621 agcttgaaaa agcagtttct cagattaagg tgtttgatgt aggtgcagag gcttttcctc
     1681 cggctctgta tgacaagatt cgcagagtaa acccggatgc ttacattatg aatggttatg
     1741 gacctacgga aactaccatc agctgtacca tgaaggtaat tacggacagc agaaacatta
     1801 ccattggtac gcctaacggt aatgtgaagg tatatattgt agataaagag aataagatcc
     1861 ttccggacgg agagaccgga gagcttgtga tcgcaggact gggcgttggc agaggttata
     1921 tgaatctgcc ggataaaaca gaggctgtat tcattgatct taacggagag agagcttata
     1981 agaccggtga ccttgcaagg atcagctctg agggtgagat tgaatttttc ggaagaatag
     2041 acaatcagat caagcttcgc ggtctgagga ttgagcttgg tgagatcgag gaggtgatca
     2101 attcctatga gggaatcatt accagcatta ctctgcctgt agataacaaa ttcctctgct
     2161 gctattttat ggctgaccgc cagatcaata cagaggagct ttctgcctat gcatcagagt
     2221 ccctggctca ttatatggtt cctgaggttt ttgtccaact ggaaaagatg cctgtgacac
     2281 agaatggcaa aattgataag aaagcactgc caaagccggt tgcacagcca aagaatctga
     2341 aagaacccca gactcctatg cagaagaaga tttttgaaat cgttgcagac gttgtggaga
     2401 atgatttttt tggaactgac acaagttttt acagggcggg gctgtcttct atcagtgcca
     2461 tgaagctttg tattctgatc tcagaggaat tcggagtgac tgtgaaaacc agtgatatcc
     2521 acgaaaacaa tacggtggag aaactggaaa aatatgtgat gcttgcaccg aagatcagaa
     2581 cctatgaaaa gagagaagtt taccctctta ccggctccca gaagggtatt tttgcagagt
     2641 gcatgaagaa tcctgagagt acggtataca atattccgtt cctgtttgaa ctggaaagct
     2701 ctgttgacgt tcagaagctg tcagatgcca tttctcagat gatcgctgca catccgtatc
     2761 tgctgacaaa ggtttattta agtgacagcg gagagatggt gcagaagcct tgtgaggaag
     2821 cctttgtacc agaggtggtc cggaccacaa atgagcagtt tgaaaagata aaagatgagt
     2881 tggtgcgtcc ctttaagctg gaaaagggac ggctgttccg ggcggggatt tatgtgatag
     2941 aagacaggaa atatcttttt acagatttcc accatatcct ggcagatggt aattcctatg
     3001 atattatttt tgaggatatc gatcgggcct atctgggtga gaaattggag aaagaatcct
     3061 acacaggctt tgatgctgcc cttgatgaag aacagcagat gaaagaggga aaatataaga
     3121 aggccgagaa atattatgac agtattttcg agggaattga gacagaatcc ctgcctcttc
     3181 ctgactgctc aggaaagact cctgagagag gatacctgtc gatgcctgtg gataccagag
     3241 agtctctggt actttctgcc tgcgagaagc tgggggttac tccaaacatt ctgtttacag
     3301 gtgtattcgg cattctcatg agcagatatt ccaattccga ggaaagtctt tttgcaacta
     3361 tttataatgg aagaaatgat tccagactgg aaaatacagt ctgcatgctt gtaaagactc
     3421 tgccggttta ctgttcctgt gatccgaaag tcaccataca ggcctatatg acagagctct
     3481 ctgagcagat tctgtcttcc atggcaaatg atatttttcc gttctctgat atttgtgcaa
     3541 agtacgggat taattctgat ctggtatttg catatcaggc agagcttggg gatgatttcc
     3601 cgatcggtga tactgttgcc aggggccatg acctttctcc ggatatgtca aagatgcctc
     3661 tgctgatcca ggtaagagaa tacgatcata aatatgtgct tactgcagaa taccgcagtg
     3721 acatgtacag tgaagccttt gtacgtggaa tgctggaatc ctatgaggca gctatggatt
     3781 ccctgctgaa agcaaaatat atttcggaag tttctgttct ttcccaaaat ggagcggaca
     3841 caattgcgga atttaataat actgcctgcg aatatgacag aagtaagacc attgctgata
     3901 tgtttgagga gctggtacag accattcctg accatacggc tgtggtattt aaggataaaa
     3961 aatatactta cagagaactg gatgagatca gcgacagact tggaaaatat atcgcatccc
     4021 agggaatcgg cagtgaggat gttgtttcca ttctgattcc ccgctgtgaa tatatggcga
     4081 ttgcgccgat gggcgtgata aaggcaggtg cagcttacca gcctctggat ccaacctatc
     4141 ctagggaccg cctgatgtac atgatggagg attcctctgc aaagcttctc attgctgaca
     4201 gagagcttct tcctctggta gacggatata aaggaccggt gctgtttaca gatcagatct
     4261 ggcagctgga ggatagggat gttgtgcttg agaagccgca gctgcatgat ctgtttatcc
     4321 ttttgtatac ttccggttcc acaggtgtgc caaagggctg tatgctggaa tatggaaata
     4381 ttactgcttt ctgtcactgg ttcaagaggt attatggcat agattcagat tccaggatag
     4441 ctgcatatgc ttcctttggt tttgatgcct gcatgatgga tatttacggt gccatcacaa
     4501 acggtgcaca gcttcacatt attccggagg aaatccgtct ggatttcatt ggactgcagc
     4561 gctattttga ggaaaatggc atcacgcatt cctttatgac tactcaggtg ggaaggcagt
     4621 ttgcgctgga gatggattgt aagagcctga gatatctttc tgtaggagga gagaaactgg
     4681 ttccatgtga gccgccaaaa gattataagt ttatcaatgc ttatggacct acagaggcga
     4741 ctatttttac gactgtattt gaagtggaca aatattatcc aaatgtcccg atcggaaaag
     4801 cacttgacaa tgtgaagctt tatattacag acaagctggg gcatatgctt cctcccggtg
     4861 catgcggaga gctgatgatc accggctggc aggtttccag aggatatctt aacaagccgg
     4921 aaaaaactgc cgaggtctat acaaagaatc tttatgatga tacaccggga tacgaagtga
     4981 tgtatcattc aggtgatgtg gcaagatttc ttccggatgg aaatatccag atcattggca
     5041 gaaaggattc ccaggttaag atcagaggtt tcaggattga gctttctgag gttgaggaag
     5101 tgatccgcag atatgagggc atcagggatg ccactgtagt tgcctttgat gatccaaatg
     5161 gtggaaaata tattgctgcc tatgtggtat cggacagcac tgttgatatc aatgccctga
     5221 atgattttat taaagagaca aagcctgcct atatggtacc tgcagttacc atgcagattg
     5281 acaaaattcc tctgaaccag aaccagaagg taaataaaaa ggctcttcct ctgcctgaga
     5341 aaaaagcagc ggagatcatt aagcctgaga atgaggttca gcagatatta tttgactgta
     5401 tcgcagaggt tctggggtat acggattttg ggattaccac agatatttat gaggcaggtc
     5461 tgacatccat cactgccatt aagctgaata tcctgatctc caaagccttt gacattgtga
     5521 tcaaaacttc agatattaag aatcatccta ctatccgaat gatggaggaa tttgtaaaaa
     5581 ctgcgggaaa agaaagcaaa agagaagtac aggaaagtta tcctcttacc aacactcagg
     5641 aggggatttt cattgagtgt actgcaaata tgggttctac catttacaat atcccgtatc
     5701 tgttaaagct tgataacaag gtggatctgg acagactggc agaagccatt gacagtactg
     5761 ttgaggcgca tccttatctg aaaacccgtc tgtttatgga tgacaacgga aatgtacttc
     5821 agaaacgaaa cgatgggctc agttataaaa caccgatttt aaacggaatg aacagagaca
     5881 ctctggtacg tccatatatg ttgtttaatg aacagctttt ccggtttgaa atctacagaa
     5941 cctgtgatgg caattatctg ttcctggacc ttcaccacat tgttgccgat ggtacatctc
     6001 tggctattat aattaatgat attaacagag cttacagcgg tgagaagctg gaaccggaag
     6061 gttatacttc ctatgatctg gcactggata acag
//
