LOCUS       gnlProkkaJDKDPIEL_16   21666 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JDKDPIEL_16.
ACCESSION   gnlProkkaJDKDPIEL_16
VERSION     gnlProkkaJDKDPIEL_16
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 18:33:41
            Original ID  :: gnl|Prokka|JDKDPIEL_16
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 11492
            Orig. end    :: 33158
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21666
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11666]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11666
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21666
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21666
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(703..909)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MATAPSSVACGDSFSKTYNPCPVTAKAVFNFYYSMKGRKEKAFFM
                     NPYCTFAAASCCFSFCSLRNTTK"
     CDS             1062..3335
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MDMIKCSTGGAYYARGEWVPADGNAPAALAAKGFDAAAVAAAKTG
                     TMAYNIMQAHNTSGDAENLKIKFDAMASHDITFVGIIQTARASGLEKFPIPYVLTNCHN
                     SLCAVGGTINEDDHRFGLSAAKKYGGIFVPPHMAVIHQYMRERFAGCGKMILGSDSHTR
                     YGALGTMAIGEGGGELAKQLLGRTYDVARPGVVAIYLTGSLPAGCGPHDVAIALVGKLF
                     KSGYVKNKVMEFVGPGIASLRQDTRNAIDAMTTETTCLSSIWETDDVTQRFLAVHGRAA
                     DYKKLAPADLAYYDGVVEVDLSAIRPMIALPMHPSNAFTIEELNANLEDILHACEQDVQ
                     KLIGRKDVQLDLCSKIENGKLRVDQGVIAGCAGGLYDSIYEAASILKGHTGGCGDYALS
                     VYPGSQPIMMELVRTGVIGELMASGATIRTAFCGPCFGAGDVPANGALSIRHTTRNFPS
                     REGSKPGSGQLSGVALMDARSIAATTANGGILTPATDVDYDPTVPEYQYDASSYDTRVY
                     QGFGKGDYDALLKFGPNIKDWPEIAPLGDNLLLKVASYITDPVTTTDELIPSGETSSYR
                     SNPLGLAEFTLSRKDPEYVGRAKAVQAEENARRAGAGDAALLAKVNAVPGCEQLNWNDI
                     QIASTIFAVKPGDGSAREQAASCQRVLGAGANIVTEYATKRYRSNLINWGMLPLQLAGA
                     TPFGLGDYVLIPNVREALKGDLQSIKAYVLGDTVKEFELYMAPLTTDERQILADGCLIN
                     FYKH"
     CDS             3350..4210
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MSCDLHIHSTCSDGAVPIERLAPIAARTGLHAIALSDHDTLLSAQ
                     YAYAHTGQDGVELIPAVELTGYDFERQHRVHLLCYYPDVDCPALREHCAIMKERRNACA
                     LQSAKELEQLYPQFTTDLAWETTKASGVLFKSGLMQALELLGLTDGSIYGETYHKLFGW
                     NPRGIVLHSPEYLPVRQVLATAKASGGAVVFAHPTVYKSMPLLRELAAEGAVDGIEVYH
                     PSNSPEDSAECLALCKQYGLVATAGTDFHGRNHKHPHPIGTCTAPDEAAAQLRAIAEKR
                     KRERT"
     CDS             4216..4479
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MSKEFSFPNKGTCSKQTNFVLNDDHTIASIEVVGGCNGNLKGICQ
                     LLTGMKAEDAIARLDGTLCGFRSTSCPDQIAKNLKKALEEMN"
     CDS             4509..4685
                     /locus_tag="ctg16_18"
                     /transl_table=11
                     /translation="MCGGSLFVWEDLLRETLSVKALRLCQIPPFVTYGDIFPRCGGSLP
                     SQGELLSISYGQR"
     CDS             4908..6680
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="MYYSSGNYEAFAHPKKPEGVDHKSAYIIGSGLAALTAACYLVRDG
                     QMKGEHVHVFEKNALAGGACDGYKYDIGYVMRGGREMDNHFEVMWDMLHSIPSLETEGA
                     SVLDEYYWLNKEDPNFSLCRATVNRGEDAHTDGKFGLSDKGAMEIMKLFFTPDEQLQDK
                     KITDFFDDEVLNSNFWMYWRTMFAFENWHSALEMKLYLKRYIHHIGGLPDFTALRFTRY
                     NQYESIILPMVRYLESFGVQFHYNTKVTDVKFDIQKGRKLASSVTVVHEGETTNIDLTE
                     NDLLFITNGGCVESCTVGAQDKATGFDPTIQPGNGWDLWKKIAAQDPSFGHPEKFCSEP
                     ELSNWESATITTLDDKIPQYIRKICKRDPFSGHTVTGGIVTVKDSSWLLSWTLNRQQQF
                     KDQPKNQLCVWVYGLFSDKPGDYVKKPMRDCTGREICMEWLYHIGVPEDQIAELAEHSA
                     NTVPVMMPYIDAFFMPRAMGDRPDVVPEGAVNFAFLGQFAETARDTIFTTEYSMRTGME
                     AVYTLLNIDRGVPEVWGSTYDVRALIDATVKLRDGKKITDMDLPLIPRLALKEALKKIE
                     GTDLEKFLKEYNAI"
     CDS             6646..6885
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MRSSSRSITPSDISFSSDRPGNGSTPPFEKDLSAAQRQGTGRSFL
                     CKNGAICVKIKLNVKIICTKRMILACLRRRSVLC"
     CDS             6922..7068
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MRYAKNKRRSFSCETTYFPSQLFKGCWCDRCRCIHGHRCACRIGL
                     LVW"
     CDS             7025..8719
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 252.5; E-value: 1.5e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_22"
                     /transl_table=11
                     /translation="MAIGAPAASACWYGDKSDVTILYTNDVHTYIDKQSPKLTYAAIAD
                     LKQSYQNAGKDVLLVDAGDHVQGTAYGSMDEGASIIKLMNAAGYDVATPGNHEFDYGMD
                     RAKAIMKEADFPYLSCNWVDLRTTLRVLPSVKVFVRGGRRIAFVGVTTPETFTKSTPAY
                     FMDKAQRKYIYDIQGGEDGKKLYDAVQKAIDKAKLLADVVIGLGHLGVDPSSSPWTSEE
                     VIAHTSGFDAFIDGHSHTVMENKQVQDASGKAVTLTQTGSYFANVGEMTIAADGTITTK
                     LIPTHEGMDAGIAAMQTGWVNTVDDMLGEKIAVGDSDFYVSDPATGKRRIRSAETNLGD
                     FVADGIYTYFNEVEKLHCDVAIMNGGGIRADVPAGDWTFKTCKQVSPFGNVACLMSVTG
                     KQIQDALEFAARFAGEDGKENGGFLQVAGATYEIHTDIPNTVQTDEKNVWIGSATGTPR
                     VQNVKIYDKASGSYLPLDPGATYALAGMNYTLRNLGDGFAMFDGAELIKDYVSEDYLVM
                     STYAMTFDGADAAGLPHLSSANSPLAAYPGYLLNYEQPYGAGRITIL"
     CDS             complement(8821..8997)
                     /locus_tag="ctg16_23"
                     /transl_table=11
                     /translation="MRSAFALRIISGISFLLEIQKSLRAFLNLLFTSGVVTVNCICNSD
                     HHLTIAALPVKMG"
     CDS             9593..9880
                     /locus_tag="ctg16_24"
                     /transl_table=11
                     /translation="MPERTTQNAQTLLSPRVPRDTEHERYHPELEEELKECLFCLKRNE
                     MMFDMEVDTDLIEQRIYERQALLCRYRYLLARARELGLHTVLTRYQPMGG"
     CDS             10001..10147
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_25"
                     /sec_met_domain="TIGR03973 (E-value: 3.7e-26, bitscore:
                     82.1, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.1e-25, bitscore: 79.7,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERIKTIATRDLTKSVKTGGCGECQTSCQSACKTSCGVANQQCEN
                     SNK"
     CDS             10215..11666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_26"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.2e-30,
                     bitscore: 97.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.8e-15, bitscore: 48.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.9e-16, bitscore: 51.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.3e-20, bitscore:
                     63.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYQLNGYNIVLDTCSGSVHVVDEVAYDVIAMYPEHTADEIVA
                     AMLAKYGSRPDVTEEDLRQCIDDVTSLKENGKLWSPDVYKDMAFDFKNRNTVVKALCLH
                     VAHSCNLSCSYCFASQGRYHGDRALMSFEVGKRAMDFLIENSGTRRNLEVDFFGGEPLM
                     NFEMVKKLVAYCREQEKIYNKNFRFTMTTNGVLIDDDVIDFCNKECHNVVLSLDGRKEV
                     NDRFRVDCAGNGSYDRIVPKFQEFVKKRGDKNYYMRGTYTHFNTDFTNDIFHMADLGFT
                     ELSMEPVVCDPSDPSALTEADLPILKEQYEILAKEMIKRDREGRGFTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDPKYLLGDIWKGVTNTAVRDEFKHCNA
                     YARKECQDCWAKLYCSGGCAANSYHATGSITGVYEYGCELFKKRMECAIMIKVAENQEL
                     AAKGIEVPIELGSTCNACADGEACE"
     CDS             11663..13081
                     /locus_tag="ctg16_27"
                     /transl_table=11
                     /translation="MSMTTPIVDFVRSYAKSGTARLHMPGHKGQSLLGFEPLDITEICG
                     ADELYAPEGIIAESEANATRLFGTAHSYYSTEGSSQCIRAMLFLALQGAPQNGKRPVLL
                     AARNAHKALLYAAALLDFDIRWLWPSAQAEGALCSCPVTAEALTGALHAMAQQGNTPFG
                     VYVTSPDYLGGVQELPALAAVCRAQDVPLLVDNAHGAYLRFLPQNCHPIAQGAAMCCDS
                     AHKTLPVVTGGAYLHLAHDAPVQDEAAVRGALALFGSTSPSYLILQSLDACNAVLAGDY
                     PRRLVQCCAALEGLRRSLNKAAAARQCPVPLAVAGAQQEPMKLTLDAAALGCTGTALAD
                     ALRRAQLECEYADPRYVVLMFTPENPPQDFERLQTALEQLLAAVPAGLSRPENRAGEFA
                     ALQQQAVQRCTIRQAVLGAQVRVPVHKALGRVCAMPTVSCPPAIPVAVSGEEITPAAIA
                     LMQRYGIKELSVLR"
     CDS             complement(13143..13820)
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="MTDLPFVSALVQADLPVWEQCLQTEFLQKMENGTLSEDCFKSYLV
                     EDSLYLREYAKIFAWGMTKATTMAAMRTYYSLLSFVQENEDLTRLRYLEQYGLREADIQ
                     SLPLRPESRAYLDCMIDAARTGEGEAECLMACLPCMLSYGWLFQKLLQRSPAVKDTYYG
                     ALVLDYAGPGYDAACRAWAERAEAACTGLSPERAARCRAIFRACSEHELHFWEMCATPR
                     TDI"
     CDS             complement(13813..14613)
                     /locus_tag="ctg16_29"
                     /transl_table=11
                     /translation="MKTALTIAGSDSSGGAGIQADIKTMTANGVFAMSAITALTAQNTT
                     GVTAIFDTTPQFLAQQIDAVFTDIYPDAVKIGMVSSAPLIDTIAERLRFYGAKHIVVDP
                     VMVATSGAKLLQDDAVQALTEKLLPLAEVLTPNIPEAEILSGMTITNAADMEAAARTIS
                     ERYGCAVLCKGGHQINDADDLLWRGGTGKWFKGKRIANPNTHGTGCTLSSAIASNLAKG
                     YDLDTAVERAKAYISGCLSAMLDLGHGSGPMDHTFNLKGDFVRD"
     CDS             complement(14836..15732)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 95.9; E-value: 3.1e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_30"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 2.9e-17, bitscore:
                     53.8, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFEKLVAIEPVSLIPSAEEELHRYAKEVVLYRDVPGSDAEMVRRI
                     GDADAVLLSYTSRMGKEVIAQCPNIRYIGMCCSLYSEESANVDIAYARTRGIKVLGIRD
                     YGDRGVVEYVLHELTGLLHGFGMPMLRDEPVEITGLKVGIVGLGVSGRMIADALQFMGA
                     EISYFARSAKPDAEAAGMTFKPLPQLLADSEVVFTCLNKNVLLLGENEFAQLGAGKVLF
                     NTSIGPGFDSAALEKWLDLPGTRFFCDTRAAAGPVAEDFFSRENVRCANVSAGRTKQAF
                     VLLSKKVLDNIRTALGE"
     CDS             complement(15751..16596)
                     /locus_tag="ctg16_31"
                     /transl_table=11
                     /translation="MNMLPQAEKRSLGYGMKTKLGIVGCGFLGNIVADAWKKGLLPDYE
                     LVGVTSRTRASAEKTAANVGCAVCEDVDALLALEPEYIVEAASVESVRAMAIPVLKRGV
                     NLVILSIGAFADLDFYAQVKAAAVEGGAKVHLASGAIGGFDVLQTVTLMAQAQGLPETA
                     GIETHTGAKGFRNTPVWAEHLLTDTEKTTVFTGNAKQAIATFPRRVNVAVATSLATTGP
                     EITGVTMHSVPGWVGDDHCITAEIEGVKAVVDICSSTSAIAGWSAVSLLRNLASPVCFY
                     "
     CDS             17168..18682
                     /locus_tag="ctg16_32"
                     /transl_table=11
                     /translation="MAYFYEEPSRTFGEYLLVPGYSSAENVPTAVSLKTPLVKYRKGQE
                     ECPLQMNIPMISAIMQSVSGDKLAIALARQGGVSFIYGSQSIENEAAMVRRVKSFKAGY
                     VVSDSNLAPTATLHDVLELKARTGHSTIAITADGTPGGKLLGIVASRDYRINHTPDDAC
                     VTTFMTPVEKLVTAPANTSLHDCNNIIWDNKINTLPLVDAEGNLVYMVFRKDYDSHKAN
                     VNELLDKNKSYVVGAGINTRDYAQRVPALVEAGVDVLCIDSSEGYSEWQSRTIGWIREH
                     YGDTVKVGAGNVVDAEGFRFLAEAGADFVKIGIGGGSICITRETKGIGRGQATAVIEVA
                     KARDEYYKETGIYVPICSDGGIVHDYHITLALAMGADFVMLGRYFARFDESPTNKVRIN
                     GQYMKEYWGEGSNRARNWQRYDLGGSTKLSFEEGVDSYVPYAGPLADGVQTTLYKVKST
                     MCNCGALSIPELQQKAKLTVVSSTSIVEGGSHDVVLKNATPSIMNG"
     CDS             18905..20422
                     /locus_tag="ctg16_33"
                     /transl_table=11
                     /translation="MNEIKVEPYIPDEDYDNPAMVVDFYEFTMANCLFLHGFKDTTLVF
                     DMFFRKNPDNQGYSISAGQRKLTRFLLDYHFNEQDIHWLRTKGMSEEFCEYLRTYKWKG
                     DMYALPEGTVCYPHVQMVRIECDLVGAILIETYLLQTMNFHSLIATKATRVTGLNTHTP
                     RSVMEFGTRRAQGESAGNDGAYAAVLGGCIGTANCLAEMKFGAEVKAVGTVAHSFIEFF
                     PTEFDAFKAFADTYPDSVSLLLDTYNIMESGLPNLIKLDDYLIEKYPNDPNRRVKSARI
                     DSGDLARGSKRLRKALDAAGKPYIKLVASNGLDEKKIANMELYEHAHFDSYGVGENLIT
                     SASDPVFGGVYKLVAVKKPDGSYTPKMKCSDSASKAIIPGKKMPWRLYDENGQAQCDLI
                     AMDGEVIEAGKPVTMVNLDSDAIERTITFIPTAVRPLLVPHILGGELAIDLPSIAEKKA
                     YIAKQLTEETWESELRLECPHKHYVNMTPAVAECRSRMYAELHGGKV"
     CDS             complement(20751..20975)
                     /locus_tag="ctg16_34"
                     /transl_table=11
                     /translation="MYQRIRDLREDRDLLQKDVAAYLKCTQVCYSNYETGKRDIPTEVL
                     IQLAHLYHTSTDYILGLTDNSAPPVPRKA"
     CDS             21114..21401
                     /locus_tag="ctg16_35"
                     /transl_table=11
                     /translation="MKLEFRQTVTCNHLTLARVCKTIDWQQPLPRCGEYVTGLDTLDGE
                     QELPVRKLLHRAQDGSCLAELPGFNIAQLRFSYRELELLAAQKGWTLQKL"
ORIGIN
        1 gttcagtcag gctgtggcag gcatcggcag ccttatttac atcatgcgcc actacccgga
       61 actgcgctgg aataaggaag aagggcgcat cagcgctccg cactgcgcaa agctttgcgc
      121 catgggcctc cccatgggtc tgcagtgcag tattaccgcc attggcagcg tggtgctgca
      181 gggcgcggtg aacggtctgg gcagcgatat cgtggcggcg cagaccgccg gcggcaaggc
      241 tgcgcagttc ctcagcgtgc cgctggagag catcggcacc gccatgacca cctacaccag
      301 ccagaatatg ggcgcgaagg atctgggccg cgtgaaccgc ggcgtgaaca ccgcactggg
      361 catcggctgc gtgtacagcg tggcctcctt cctcatcctg cgcgtgctgg acaagcccct
      421 gatcggcctg ttcctggacg caggcgagac cgccattatg gccaatgcgc aggacttcat
      481 cttctggaac agtgtgttct acatcccgct ggcagtgctt atcatctacc gctacaccat
      541 tcagggcctg gggcactccg gccttgccat gtttgccggt gtggccgaga tgatcgcccg
      601 cgccatggtg ggcttctggt tcgtgccgct gtggggctac tttgccgcct gcatcgcaag
      661 cccggtggca tggctctttg cctgcttctt cctgatcccg gcctattttg tggtgttccg
      721 taaactgcaa aaggaaaagc agcaggaagc cgccgcaaag gtgcagtaag ggttcataaa
      781 aaatgctttt tcttttcgcc ctttcatgct ataataaaag ttaaatacgg cttttgccgt
      841 aacagggcag gggttataag tctttgaaaa gctgtcgccg caggcgactg atgagggtgc
      901 tgttgccaag aaatacccct catccggtgc tgtgcgccac cttcccccaa ggggtgaagg
      961 ctaaggggac ggctgttttc gggatgaata gccgcactgc cggggcaatg cccgcaattg
     1021 cggcgggcgg gaaaatacaa aaagagaggc gaatcgagat gttggatatg atcaaatgca
     1081 gcaccggcgg tgcgtactat gcgcgcggag agtgggtgcc cgcagatggc aatgcacccg
     1141 cggcactggc agcaaagggc tttgatgccg ctgccgttgc cgcggctaag accggtacca
     1201 tggcctacaa tattatgcag gcacacaaca ccagcggcga tgccgagaac ctgaagatca
     1261 agtttgatgc catggcaagc catgacatca cctttgtggg cattatccag accgcccgtg
     1321 cttccgggct ggaaaagttc cccattcctt atgtgcttac caactgccac aacagcctgt
     1381 gcgctgtggg cggcaccatt aacgaggacg accaccgctt tggcctgtcc gctgccaaaa
     1441 agtacggcgg tatctttgtg cccccgcaca tggcagtcat ccaccagtat atgcgcgagc
     1501 gctttgccgg ctgcggcaaa atgatccttg gctcggactc ccacacacgc tacggcgcac
     1561 tgggcaccat ggctatcggc gagggcggcg gcgagctggc aaagcagctg ctgggccgca
     1621 cctatgatgt tgcccgccct ggcgtggtgg ccatctacct gaccggcagt ctgccggcgg
     1681 gctgcggccc ccacgatgta gccattgccc ttgtgggcaa gctgttcaag agcggctacg
     1741 tcaaaaacaa ggtcatggag ttcgtgggcc ccggcattgc ttccctgcgg caggataccc
     1801 gcaacgccat tgatgccatg accaccgaga ccacctgcct gtcctccatc tgggagaccg
     1861 acgatgtcac ccagcgtttt ctggcggtgc acggccgtgc agcagactac aaaaagcttg
     1921 caccggcaga ccttgcctac tacgatggcg tggtggaagt ggatctttct gccatccgtc
     1981 ccatgatcgc cctgcccatg cacccctcca atgcctttac catcgaggaa ctgaacgcaa
     2041 atctggagga cattctccac gcctgcgagc aggatgtgca gaagctgatc ggccgcaagg
     2101 atgtgcagct ggatctgtgc agcaagatcg aaaacggcaa gctgcgtgtg gatcagggcg
     2161 tcattgcagg ctgcgcaggc ggtctgtacg acagcatcta cgaggctgct tccatcctca
     2221 agggtcatac cggcggctgc ggcgactacg ccttgagcgt ttaccccggc agtcagccca
     2281 tcatgatgga actggtgcgc accggcgtca ttggcgagtt gatggccagc ggcgctacca
     2341 tccgcaccgc cttctgcggc ccctgcttcg gcgcaggcga tgtgcccgct aacggcgctc
     2401 tgtccatccg tcacaccacc cgcaacttcc ccagccgcga aggctctaag cccggcagcg
     2461 gtcagctgtc cggtgtggcg ctgatggatg cccgcagcat tgcagccacc accgcaaacg
     2521 gcggtatcct gactcctgcc accgacgttg attacgatcc caccgtgccg gagtaccagt
     2581 acgatgcttc cagctacgac acccgcgtgt atcagggctt tggcaaaggc gattacgacg
     2641 ccctgctcaa gttcggcccc aacatcaagg actggccgga gatcgcaccg ctgggcgaca
     2701 acctgctgct gaaggtggct tcttatatca ccgaccccgt caccaccacc gacgagctga
     2761 tcccctccgg tgagacctct tcttaccgct ctaaccccct gggtctggcc gagttcaccc
     2821 tcagccgcaa ggatccggag tatgtgggcc gcgccaaggc tgtgcaggcc gaagagaacg
     2881 cccgccgcgc cggtgcaggg gacgctgccc tgctggcaaa ggtgaacgcc gtgcccggct
     2941 gcgaacagct gaactggaac gatatccaga tcgcttctac catctttgcg gtcaagcccg
     3001 gcgatggctc tgcccgtgag caggccgcca gctgccagcg tgtgctgggt gccggtgcca
     3061 atatcgtaac cgagtacgcc accaagcgtt accgctccaa cctgatcaac tggggcatgc
     3121 tgcccctgca gctggcaggt gccaccccct ttggtctggg ggattatgtg ctcatcccca
     3181 atgtgcggga agcactcaag ggcgacctgc agagcatcaa ggcctatgtt ctgggcgata
     3241 ccgtcaagga gtttgagctg tacatggctc cgctcaccac cgacgagcgc cagatcctgg
     3301 ctgacggttg cctgatcaat ttctataagc actaaggaag taacccgcta tgtcctgtga
     3361 cctgcatatc cattccacct gctcggatgg tgctgtgccc atcgagcggc tggcacccat
     3421 cgccgcccgc accgggctgc acgccatcgc cctttcggac cacgacaccc tgctcagcgc
     3481 ccagtacgcc tatgcccaca ccgggcagga cggggtagag ctgatccccg ccgtggagct
     3541 gaccggctac gactttgagc gccagcaccg ggtacacctg ctgtgctact acccggacgt
     3601 ggactgcccg gcgctgcggg agcactgcgc catcatgaag gagcgccgca acgcctgcgc
     3661 tttgcagagc gcaaaggagc tggaacagct gtacccgcag tttaccaccg accttgcatg
     3721 ggagaccaca aaggccagtg gggtactgtt caaaagcggg ctgatgcagg cactggaact
     3781 gctgggtctg accgatggca gcatctacgg cgagacctac cacaagctgt tcgggtggaa
     3841 cccccggggc atcgtgctgc actcgccgga gtatctgccg gtgcggcagg tgctggctac
     3901 cgccaaggca agcggcggcg cggtggtgtt tgcccacccc acggtgtata aaagtatgcc
     3961 cctgctgcgg gagctggcag cagagggcgc agtggacggc attgaagtgt accatcccag
     4021 caacagcccg gaggacagcg ccgagtgcct tgccctgtgc aaacagtacg gccttgtggc
     4081 tactgcgggc acggacttcc atggccgcaa ccacaagcac ccccacccca tcggcacctg
     4141 caccgcaccg gacgaagccg cagcgcagct gcgcgccatc gccgaaaaac gtaaaagaga
     4201 gaggacgtaa agactatgag caaggaattt tccttcccga acaagggtac ctgctccaag
     4261 cagaccaact ttgtgctgaa cgatgaccac accattgctt ccattgaggt cgtcggcggc
     4321 tgcaacggca acctgaaggg catctgccag ctgcttaccg gcatgaaggc agaggacgcc
     4381 attgcccgtc tggacggcac gctgtgcggc ttccgcagca ccagctgccc ggaccagatt
     4441 gcaaagaacc tgaaaaaggc tctggaagag atgaactaaa atccaccgga gagccgctgc
     4501 acagaacctt gtgcggcggc tctctttttg tatgggaaga tttgcttaga gaaaccctct
     4561 cagtcaaagc cttgcggctt tgccagattc ccccttttgt cacctacggt gacatcttcc
     4621 cccggtgcgg gggaagtctg ccctctcagg gggagctttt aagtatctct tacggtcagc
     4681 gctgataaag ctctcccttc gggagagctg gcgcgaagcg cctgagaggg tttactttat
     4741 gtcacaattt gtacgcattt ccagcaaatg agggcggatg taaaaaatct atacaccggg
     4801 caaagtttgt ttgttgttcc ggttcacttt gcggggtata ctgttgccat agagaacagc
     4861 acgatgaagg ctgtgaaacg aaaatatgga agcagggagg cttttttatg tactattcca
     4921 gtggcaatta tgaagctttt gcacacccca aaaagccgga gggcgtggat cataaatccg
     4981 cttatatcat cggctccggt ctggctgcgc tgaccgctgc ctgctatctg gtgcgcgacg
     5041 gccagatgaa gggcgagcac gtccatgtgt ttgaaaagaa cgcactggcc ggcggtgcct
     5101 gcgatggcta caagtacgat atcggctatg tgatgcgcgg cggccgcgag atggacaacc
     5161 acttcgaagt tatgtgggat atgctgcact ccatcccctc tctggagacc gagggtgcca
     5221 gcgtgctgga cgagtactac tggctgaaca aggaggatcc caacttttcc ttgtgccgtg
     5281 ccaccgtcaa ccgcggcgag gatgctcaca ccgatggcaa attcggcctg tccgataagg
     5341 gtgccatgga gatcatgaag ctgttcttta ccccggacga gcagctgcag gataaaaaga
     5401 tcaccgattt cttcgatgac gaggtgctca actccaactt ctggatgtac tggcgcacca
     5461 tgttcgcctt cgagaactgg cacagcgctc tggagatgaa gctgtacctc aagcgctata
     5521 tccaccacat cggcggtctg ccggacttta ccgccctgcg ctttacccgc tataatcagt
     5581 acgaatccat catcctgccc atggtgcgct atctggaaag ctttggcgtg cagttccact
     5641 acaacaccaa ggtcacggat gtgaagttcg acatccagaa gggccgcaag ctggcaagct
     5701 ctgtcaccgt ggtgcatgag ggcgagacca ccaacattga tctgaccgag aacgatctgc
     5761 tgttcatcac caacggcggc tgcgtggaaa gctgcaccgt gggtgcacag gataaggcca
     5821 ccggctttga ccccaccatc cagcccggca acggctggga tctgtggaag aagatcgccg
     5881 cacaggaccc ctccttcggt cacccggaaa agttctgctc cgagccggaa ctgagcaact
     5941 gggagagcgc caccatcacc acgctggacg acaagatccc tcagtatatc cgcaagatct
     6001 gcaagcgcga ccccttcagc ggccacaccg tcaccggcgg catcgtcacc gtcaaggact
     6061 ccagctggct gctcagctgg acgctgaacc gtcagcagca gtttaaggat cagcccaaga
     6121 accagctgtg cgtttgggtg tacggcctgt tcagcgataa gcccggcgat tacgtcaaga
     6181 agcccatgcg cgactgcacc ggccgcgaga tctgcatgga gtggctgtac cacatcggtg
     6241 tgcccgagga tcagatcgcg gagctggcag agcacagtgc caacaccgtg cctgtgatga
     6301 tgccctatat cgacgccttc ttcatgcccc gtgccatggg cgaccgtccc gatgttgtgc
     6361 ccgagggtgc tgtgaacttc gccttccttg gtcagtttgc cgagaccgcc cgcgatacca
     6421 tcttcaccac cgagtactcc atgcgcaccg gtatggaggc tgtgtacacc ctactgaaca
     6481 tcgaccgcgg cgtgcccgag gtctggggca gcacctacga tgtgcgcgct ctgatcgatg
     6541 ccaccgtgaa gctgcgcgac ggcaaaaaga tcaccgacat ggatctgccg ctgatcccgc
     6601 gtctggctct gaaggaagcc ttgaagaaga tcgagggcac cgaccttgag aagttcctca
     6661 aggagtataa cgccatctga tatttccttc tcctccgata gacccggcaa cgggtcaaca
     6721 cccccctttg aaaaagacct ctccgctgct cagcgacagg gcacggggag gtcttttttg
     6781 tgtaaaaatg gtgcaatatg cgtcaaaata aagctgaacg tgaaaataat ttgtaccaaa
     6841 agaatgattt tggcttgtct gcggcggcgt tctgtgctat gctagagcta ttgaaagggc
     6901 aggagggaag agcctgccca aatgcgatac gccaaaaata aaaggaggtc gttttcctgt
     6961 gaaacaactt atttcccgtc gcagcttttt aaaggctgct ggtgtgaccg ctgccgctgc
     7021 atccatggcc atcggtgcgc ctgccgcatc ggcctgctgg tatggtgaca agtctgacgt
     7081 taccatcctg tacaccaacg atgtccatac ctacatcgac aagcagagcc ccaagctgac
     7141 ctacgctgcc attgccgacc tgaagcagag ctatcagaat gccggcaagg atgtgctgct
     7201 ggtggatgca ggcgaccatg tgcagggcac tgcctacggc tccatggacg agggtgcttc
     7261 catcatcaag ctgatgaacg ctgccggtta cgatgtcgcc acccccggca accacgagtt
     7321 tgactacggc atggaccgtg ccaaggccat catgaaggaa gccgacttcc cgtacctgtc
     7381 ctgtaactgg gtagacctgc gcactacgct gcgtgtgctg ccctccgtca aggtgttcgt
     7441 gcgcggcggc agacgcatcg cctttgtggg tgtgaccacc cccgagacct ttaccaagtc
     7501 caccccggcc tactttatgg ataaggcaca gcgcaagtac atctacgata ttcagggcgg
     7561 cgaggacggc aaaaagctct atgacgccgt gcagaaggcc attgataagg caaagcttct
     7621 ggcagatgtg gtcatcggtc tgggccatct gggcgtagac ccctcttcct ctccgtggac
     7681 cagtgaggaa gtcattgccc acaccagcgg ctttgacgcc tttatcgacg gccactccca
     7741 taccgtaatg gagaacaagc aggtgcagga tgcctccggc aaggctgtca ccctgaccca
     7801 gaccggttct tactttgcca acgttggcga gatgaccatc gctgcggacg gcaccatcac
     7861 caccaaactc atccccaccc acgagggcat ggacgcaggc atcgccgcca tgcagactgg
     7921 ctgggtgaac accgtggacg atatgctggg cgagaagatc gctgtgggcg acagcgattt
     7981 ctacgtctct gaccctgcca ccggcaagcg ccgcatccgc tctgccgaga ccaacctcgg
     8041 cgactttgtg gctgacggca tctacaccta cttcaacgag gtggaaaagc tgcactgtga
     8101 tgtggccatc atgaacggcg gcggtatccg cgccgatgtg cccgcaggcg actggacctt
     8161 caagacctgc aagcaggtca gcccctttgg caacgtggcc tgcctgatgt cggttaccgg
     8221 caagcagatc caggacgcat tggagtttgc agcccgcttt gcaggcgagg acggcaagga
     8281 gaacggcggc ttcctgcagg tggccggtgc tacctacgag atccacaccg atatccccaa
     8341 cacagtgcag accgacgaga agaacgtctg gatcggcagc gccaccggca ccccgcgcgt
     8401 gcagaacgtg aagatctacg ataaggcttc cggcagctat ctaccgctgg acccgggtgc
     8461 tacctacgca ctggccggca tgaactacac cctgcgtaat ctgggcgacg gctttgccat
     8521 gtttgacggc gcagagctga tcaaggacta tgtgtccgag gattatctgg tgatgtctac
     8581 ctacgccatg acctttgacg gcgcagatgc tgcgggtctg ccgcacctgt ccagcgccaa
     8641 cagcccgctg gccgcatacc ccggctacct gctcaactac gagcagccct acggcgcagg
     8701 ccgcatcacc attctgtaaa agaaagccct atcagggcag gtcaactgta tagcaaaaac
     8761 cgggcagtct gcgggctgcc cggttttttg tgcagtacga acgattggaa atgcgctccg
     8821 ctatcccatt ttcacgggga gggctgcaat ggttaaatgg tggtctgaat tgcaaatgca
     8881 gttgaccgtt acgaccccac tggtgaaaag gagattcaga aaagcccgca ggcttttctg
     8941 aatctcgagt aaaaaactaa ttccgctaat tatgcgcaga gcgaacgcgg agcgcattct
     9001 aaatcgtccc gccccggcag gggtgactct tcaaaagttc cctatgaccc acaggggttt
     9061 tgaagagtca tgaacaaaaa gcaaagaaaa ctgcgttttc aggccatgac tcttcatctt
     9121 gaagagtgaa cttttaaacg ctgatgcgct tctttttcgt cactcttcaa aaatccaaag
     9181 tggtaataga gttatgactc ttcaagtttt gaagagtcac ggccttgcgg ctgtggttcg
     9241 gaatgatata aacagaaaag ccacctgaac ttcctcagat ggctttagtc tggttgggga
     9301 tgagagaatc gaactcccac aagtagagtc agagtctacc gcactaccac tatgcaaatc
     9361 cccaatattc tgttgtgttt tgcggggtga gccgctcaac gtgtgctatt atacgggaaa
     9421 agcccggagt tgtcaagcat atttttgaaa aaagttgtac ttttttggaa aatgccgcag
     9481 cagcgccgga taatctatgc cggagcgctg ccacgcttcg gcaggttctg cacactgcac
     9541 cgcctatact ggaaggtaca aaaccttaca aagcaccaga aggaggatgc ctatgccgga
     9601 acgaaccaca cagaatgccc agaccctgct ttcgccccgc gtcccgcggg ataccgagca
     9661 cgagcgctac cacccggagc tggaggagga actgaaggaa tgcctgttct gtttgaagcg
     9721 caacgagatg atgtttgaca tggaggtgga tacggacctg atcgagcagc gtatttacga
     9781 gcgtcaggcg ctgctgtgcc gttaccggta cttactggca cgcgcccggg agctggggct
     9841 gcatacggtg cttacccgct accagcccat gggcgggtga aaaggcttag cgaaaaaatc
     9901 ttgacaaaag gcgcgctgcg tgatatccta ttacaagata aaagcgtacc ggaactatgt
     9961 ccggcgcgat aaatttttga gagttagaga ggtttctatc atggagcgta ttaagactat
    10021 tgctactcgt gacctgacca agagcgttaa gaccggtggc tgcggcgagt gccagacttc
    10081 ctgccagtcc gcctgcaaga cctcctgcgg cgtggctaac cagcagtgcg agaacagcaa
    10141 caagtaattt ttgcaaaccc tatgccgcct ttgccgggcg gcattttttt gtgtaatctg
    10201 gaatggagtg taaaatggta catcagtatc aattgaacgg ttataacatc gtgctggaca
    10261 cctgcagcgg ctcggtgcac gttgtggacg aggtggccta cgatgtcatc gccatgtacc
    10321 cggagcatac cgcagacgag atcgttgccg ccatgctggc aaaatacggc agccgcccgg
    10381 acgtgaccga ggaggatctg cgccagtgca tcgatgacgt gaccagcctg aaggaaaacg
    10441 gcaagctgtg gagcccggat gtctataagg acatggcctt cgactttaaa aaccgcaaca
    10501 ctgtggtaaa ggcactgtgc ctgcacgttg cccatagctg caacctgagc tgctcttact
    10561 gctttgcctc gcagggacgt taccacggcg accgcgccct gatgagcttt gaagtgggca
    10621 agcgcgccat ggacttcctc atcgagaaca gcggcacccg ccgcaatctg gaagtggact
    10681 tctttggcgg tgagccgctg atgaactttg agatggtcaa aaagctggtg gcctactgcc
    10741 gcgagcagga gaagatctat aacaagaact tccgctttac catgaccacc aacggtgtgc
    10801 tcattgatga cgacgttatc gacttctgca acaaggagtg ccacaatgtg gtgctgagtc
    10861 tggatggccg caaggaggtc aacgaccgct tccgcgtgga ctgtgcaggc aacggcagct
    10921 acgaccgcat cgtgcccaag ttccaggagt tcgtcaagaa gcgcggcgac aagaactact
    10981 atatgcgcgg cacctatacc cactttaaca ccgactttac caacgatatc ttccacatgg
    11041 cagacctcgg ctttaccgag ctgagcatgg agccggtggt ctgcgacccc agcgacccca
    11101 gcgccctgac tgaggccgac ctgcccatcc tgaaggagca gtacgagatc cttgccaagg
    11161 agatgatcaa gcgcgaccgc gagggcagag gctttacctt ctaccactac atgatcgacc
    11221 tgaccggcgg cccctgcatc tataagcgca tctccggctg cggctccggc accgagtaca
    11281 tggctgttac cccctggggc gatctgtacc cctgccacca gttcgtgggc gaccccaagt
    11341 acctgctggg cgatatctgg aagggcgtta ccaacaccgc tgtgcgggat gagttcaagc
    11401 actgcaacgc ctacgcccgc aaggagtgtc aggattgctg ggcaaagttg tactgctccg
    11461 gcggctgcgc tgccaactcc taccacgcca ccggcagcat taccggcgtg tacgagtacg
    11521 gctgcgagct gttcaaaaag cgcatggagt gcgccattat gatcaaggta gccgagaatc
    11581 aggaactggc agccaagggc atcgaggtgc ctattgagct gggctctacc tgcaacgcct
    11641 gcgctgacgg cgaagcctgc gaatgagcat gaccaccccc atcgtggatt ttgtgcgcag
    11701 ctatgcaaag tccggtaccg cccggctgca tatgcccggc cacaaggggc agagcctttt
    11761 aggctttgag ccgctggata tcaccgagat ctgcggtgcg gacgagcttt acgcgccgga
    11821 gggcattatt gccgagagtg aagccaacgc cacccggctg ttcggcacgg cgcacagcta
    11881 ttacagcacc gaggggtcgt ctcagtgcat ccgtgccatg ctgtttctgg cgctgcaagg
    11941 cgcaccgcaa aacggtaagc gcccggtgct gctggccgcc cgcaacgccc acaaggcgct
    12001 gctgtatgcg gcggcgctgc tggattttga tatccgctgg ctctggccgt ctgcgcaggc
    12061 agagggtgca ctgtgcagct gccccgtcac agccgaagcg ctgacagggg ctttgcacgc
    12121 gatggcacag cagggcaaca ccccctttgg cgtgtacgtc accagcccgg attatctggg
    12181 cggggtgcag gaactcccgg cgctggccgc tgtctgccgg gcgcaggacg tgcctttgct
    12241 ggtggataac gcccacgggg cctacctgcg ctttctgccg cagaactgcc accccatcgc
    12301 acagggcgcg gccatgtgct gcgactctgc ccacaagact ctgccggtgg tcaccggcgg
    12361 tgcgtatctg catctggcgc acgatgcccc tgtgcaggac gaagcggctg tgcggggggc
    12421 gctggcgctg ttcggctcta ccagcccctc ttacctcatt ttgcagtcgc tggatgcctg
    12481 caatgcggtg ctggcagggg actacccccg gcggctggtg cagtgctgcg cggcgctgga
    12541 aggtctgcgc cgcagcctga ataaggccgc agcggcgcgg cagtgcccgg tgccgctggc
    12601 agttgccggg gcacagcagg agccgatgaa gcttacgctg gacgccgccg cccttggctg
    12661 caccggcaca gcgctggcag atgctttgcg ccgcgcacag ctggagtgcg agtatgccga
    12721 cccccgctat gtggtgctga tgttcacccc ggaaaacccg ccgcaggact ttgaacgcct
    12781 gcaaacggcg ctggaacagc ttctggctgc tgtgcctgcc ggactgtccc gccccgagaa
    12841 ccgggcagga gagtttgccg ccttgcagca gcaggcggtg cagcgctgta ccatccggca
    12901 ggcggtgctg ggtgcacagg tgcgcgtccc ggtgcacaag gcactgggac gggtgtgtgc
    12961 catgcctacg gtgtcctgcc cgcccgccat ccctgtggcg gtcagcggcg aggagatcac
    13021 cccggcagcc atcgccctga tgcagcgcta cggcatcaaa gaactctcgg tgctgcgata
    13081 aagattttat aagaagagaa cccggaaggt ctgcggacct tccgggttct ctatatttat
    13141 tcttaaatat ccgtccgggg cgtggcgcac atctcccaga agtgcagctc gtgctccgag
    13201 caggcgcgga agatcgcgcg gcaacgggcg gcacgctccg gcgaaaggcc ggtgcaggct
    13261 gcttcagcgc gttctgccca tgcgcggcag gcggcatcgt agccgggacc ggcgtagtcc
    13321 agcaccagcg cgccgtagta ggtgtccttt acggcggggg agcgctgcaa aagcttctgg
    13381 aatagccacc cgtagctcag catacagggc aggcaggcca tcaggcactc ggcctcgccc
    13441 tcgccggtgc gcgcagcgtc gatcatgcag tccagatagg cgcggctttc cgggcgcagg
    13501 ggcagggact ggatatcagc ttcccgcaga ccgtactgct ccagataccg cagccgggtc
    13561 aggtcctcgt tctcctgcac aaaggacagc agggaatagt aggtgcgcat ggccgccatg
    13621 gtggtggcct tggtcatgcc ccacgcaaaa attttggcgt actcccgcag atacaggctg
    13681 tcctccacaa ggtagctttt aaagcagtcc tcgctcaggg tgccgttttc catcttttgc
    13741 agaaactcgg tctgtaagca ctgctcccac acaggcaggt ctgcctgcac cagcgccgaa
    13801 acgaagggca ggtcagtcac ggacaaaatc tcccttcagg ttgaaggtgt gatccatggg
    13861 cccggagcca tgccctaaat ccagcatggc agacagacag ccggaaatgt aggccttggc
    13921 acgctccacg gcggtgtcga ggtcgtaccc cttggccaga ttggaagcga tggcgctgga
    13981 cagggtgcag ccggtgccgt gggtgttggg gtttgcaatg cgcttgccct tgaaccactt
    14041 gccggtgccg ccgcgccaca aaaggtcgtc ggcatcgttg atctggtggc cgcccttgca
    14101 cagcacggcg cagccgtaac gctcgctgat ggtgcgggca gcggcttcca tgtcggcggc
    14161 gtttgtaatg gtcatgccgg acaagatctc ggcctccggg atgttggggg taagcacctc
    14221 agccagcggc agcagctttt cggtcagcgc ctgtacagca tcgtcctgca gcagctttgc
    14281 gccggaggtg gccaccatca cagggtccac cacgatgtgc tttgcaccgt agaagcgcag
    14341 ccgctcggcg atagtgtcga tgagcggggc agaggatacc atgccgatct tcacagcatc
    14401 ggggtagata tcggtaaaca cggcgtcgat ctgctgtgcc agaaactgcg gcgtggtgtc
    14461 aaaaatggcg gtcacaccgg tggtgttctg tgccgtcagg gcggtaatgg cgctcatggc
    14521 aaacacgccg ttggcggtca tggtcttgat atcggcctgg atcccggcgc cgccgctgga
    14581 atcactgccg gcaatggtca atgcagtttt cataggtgaa atgctccttt gcagcaaaaa
    14641 tgcggatatg cccgcaaaga catatccgca gataaaagcg ctatctccct acgttggcat
    14701 gatccaaatc aggtcacagg tcagggcaat acagcccact ctcagcccgc ttgcacgggc
    14761 tcccttttta tactagaaag cataccacaa tcggggaaaa gatgcaagaa aaacaggctg
    14821 cgcaaaatgc accgcttatt cgcccagtgc ggtgcggatg ttgtccagca cctttttgct
    14881 cagcagcaca aaggcctgct tggtgcggcc tgctgacaca ttggcgcagc gcacgttttc
    14941 ccgggaaaag aagtcctcgg ccacggggcc tgcggcggcg cgggtgtcgc agaagaagcg
    15001 ggtgccgggc aggtcaagcc acttttccag tgcagcggag tcaaagccgg ggccgatgga
    15061 agtgttgaac agcaccttgc ctgcgcccag ctgggcaaac tcattttcgc ccaacagcag
    15121 cacgttcttg ttcaggcagg tgaacactac ctcgctgtcc gccagcagct ggggcagggg
    15181 cttgaaggtc ataccggcag cctcggcgtc cggctttgcg ctgcgggcaa agtagctgat
    15241 ctctgcgccc ataaattgca gcgcatcggc gatcatccgg ccagaaacgc ctagacccac
    15301 aatgccaacc ttcagaccgg tgatctccac cggctcgtcc cgcagcatgg gcatcccaaa
    15361 gccgtgcagc aggccggtca gctcgtgcag aacgtactcc acaacgccgc ggtcgccgta
    15421 gtcccggata cccaacacct tgatgccccg ggtgcgtgcg taggcgatat ccacattggc
    15481 actctcctca gagtacaggc tgcagcacat gccgatatag cggatgttgg ggcactgcgc
    15541 aatgacttcc ttgcccatgc gggaggtata actcagcagc acggcatcgg cgtctccgat
    15601 acggcgcacc atttcggcgt cactgccggg cacgtcccgg tacagcacca cctctttggc
    15661 atagcggtgc agctcttcct cggcagaggg gatcaggctg acaggctcaa tggcaacaag
    15721 cttttcaaac atggcagact cctccttata ttaatagaag caaacgggcg aggccagatt
    15781 gcgcagcagg gagacggcgc tccagcccgc aatggcgctg gtggaagagc agatatccac
    15841 cacagccttc acgccctcga tctcggcggt gatgcagtgg tcgtcgccca cccagccggg
    15901 cacggagtgc atggtcacac cggtgatctc gggaccggtg gtggccagag aggtagccac
    15961 cgccacgttt acccggcggg ggaaggtagc aatggcctgc ttggcgttgc cggtgaacac
    16021 ggtggtcttt tcggtgtcgg tcagcagatg ctctgcccac accggcgtat tgcggaagcc
    16081 ttttgcaccg gtatgggtct cgatgccggc agtctccggc agaccctgtg cctgtgccat
    16141 cagggtgacg gtctgcagca cgtcaaagcc gccgatggca ccgctggcca gatgcacctt
    16201 ggcaccgccc tccacggcgg ctgccttgac ctgtgcgtag aaatccagat ccgcaaaggc
    16261 accgatggat agaatgacca gattcacgcc ccgcttcagc acggggatgg ccatggcgcg
    16321 caccgactcc accgaggcag cctccacgat gtactccggc tcaagtgcca gcagcgcgtc
    16381 cacgtcctca cagacggcgc agccgacgtt ggcggcggtc ttttcagccg aagcgcgggt
    16441 gcggctggtc acgcccacca gctcgtagtc cggcagcaga cccttcttcc acgcgtcagc
    16501 cacgatgttg cccagaaaac cgcagcccac aatacccaat tttgttttca taccgtatcc
    16561 taaactcctt ttttctgcct gtggcagcat attcataacc agtataccat atcgggtaca
    16621 aaaaggaaaa tgatgtttgc agcagcccgg cggggcagga cataaaaagt taacaaaata
    16681 aattacaaaa aaattacaaa accctattgc aaaatggttt caaaagagtt acaatatggt
    16741 tacagcaagg gcaaagcccc aaggctgtgt gtgaaatctt tttcttcttg tttttgggat
    16801 actgggcgcg gatcctcctc ctccggctgt tctccttcac agctatgatc catgcgccgc
    16861 acaggcagtg tcccgcttcg tgtgcaaaag ggctcgtccg gtattctgga cgagcttttt
    16921 tgcgttctgc aagccctgtt ttgcctgcaa aagtgatact tcaaaaatca aagtatgacc
    16981 aatgcctgaa aacgcttggc aatttgtctg tttttccgca aaggacaatt ataaagtttg
    17041 gcgcggcagg ggtttgtatt cttgcgggct ttgtggtaaa gtatatacaa tcaatttata
    17101 ggcagcaaac atgaatgatt ttgatgctga tttgtatcgg atgcgttaag agaaaaggag
    17161 tttgattatg gcttatttct acgaagaacc ttcccgcacc tttggcgagt acctgctggt
    17221 ccccggctat tcctctgcgg agaatgtgcc cacggcggtc agcctgaaga ccccgctggt
    17281 caagtaccgc aagggacagg aggagtgccc gctgcagatg aatatcccca tgatcagcgc
    17341 catcatgcag tcggtctccg gcgataagct ggccattgca ctggctcgtc agggcggcgt
    17401 ttcctttatc tatggctctc agagcatcga gaacgaggct gccatggtgc gccgcgtcaa
    17461 gagcttcaag gccggttatg tggtgtccga ttccaatctg gctcccaccg ccaccctgca
    17521 tgatgtgctg gaactgaaag cgcgcaccgg tcactccacc atcgccatca ctgccgacgg
    17581 cactccgggc ggcaagctgc tgggcatcgt ggcctcccgc gattaccgca tcaaccacac
    17641 cccggacgat gcctgcgtta ccacttttat gactcccgtt gaaaagctgg tcaccgctcc
    17701 ggccaacacc tctctgcacg actgcaacaa catcatctgg gacaacaaga tcaacaccct
    17761 gccgctggtg gatgccgagg gcaatctggt gtatatggta ttccgcaagg actacgattc
    17821 ccacaaggca aacgtcaacg agctgctgga caagaacaag agctatgttg tgggtgccgg
    17881 tatcaatacc cgcgactacg cccagcgcgt gcccgcactg gtagaggccg gtgtggatgt
    17941 gctgtgcatc gactcctccg agggctactc cgagtggcag agccgcacca tcggctggat
    18001 ccgcgagcac tacggcgata ccgtcaaggt gggtgccggc aacgtggtgg acgccgaggg
    18061 cttccgcttc ctcgctgagg ctggtgcaga ctttgtgaag atcggcatcg gcggcggctc
    18121 catctgcatc acccgtgaga ccaagggcat cggccgtggt caggctactg ctgtcatcga
    18181 ggttgccaag gctcgtgacg agtactacaa ggagaccggc atctatgtgc ctatctgctc
    18241 cgacggcggc atcgtccacg actaccacat caccctcgcg ctggctatgg gcgcagactt
    18301 tgtgatgctg ggccgttact ttgcccgctt tgacgagagc cccacgaaca aggtgcgcat
    18361 caatggccag tatatgaagg agtactgggg cgaaggctcc aaccgtgccc gcaactggca
    18421 gcgctacgat ctgggcggct ccaccaagct gagctttgag gagggcgtgg acagctatgt
    18481 gccttacgcc ggtcctctgg cggacggcgt gcagaccacc ctgtacaagg tgaagagcac
    18541 catgtgcaac tgcggcgctc tgtccatccc cgagctgcag cagaaggcca agctgaccgt
    18601 tgtttcctct acctccatcg tggagggcgg cagccacgac gttgtgctga agaacgccac
    18661 ccctagcatc atgaacggct aagcctgttc tgagcaagcg attactttga acaaagagac
    18721 cgctgcacag cgtttgtgca gcggtctctt tttgcacaaa aatacttgca caggcaggga
    18781 aatcgtgcta tcatggtaga aacgctttgt cttgacaggg cagagaatcc ccctgccggg
    18841 caagcggcag gcggcgcagc ggggaagacc cccgcgccgg gcataaatag agaggaaaac
    18901 gttcatgaac gagatcaagg tcgagcctta tatccctgac gaggactacg ataaccccgc
    18961 gatggtggtg gacttttacg aattcaccat ggcaaactgc ctgttcctgc atggttttaa
    19021 ggataccacg ctggtgtttg atatgttctt ccgcaagaac ccggacaatc agggctattc
    19081 catcagcgca ggccagcgca agctgacccg ctttttgctg gactatcact tcaatgagca
    19141 ggacatccac tggctgcgca ccaagggcat gagcgaggag ttctgcgagt atctgcgcac
    19201 ctacaagtgg aagggtgata tgtacgccct gcccgagggc acggtctgct acccccatgt
    19261 gcagatggtg cgcatcgagt gcgatctggt gggcgcgatc ctgatcgaga cctacctgct
    19321 gcagaccatg aacttccata gcctgatcgc caccaaggca acccgcgtta ccggtctgaa
    19381 cacccacacc ccccgcagcg tcatggagtt cggcacccgc cgcgcacagg gcgagagcgc
    19441 cggtaacgat ggcgcttacg cagcagtgct gggcggctgc atcggcacgg ccaactgtct
    19501 ggcagagatg aagttcggtg cagaggtcaa ggccgtgggc accgtggcac acagctttat
    19561 cgagttcttc cccaccgaat tcgatgcctt caaggccttt gccgatacct acccggattc
    19621 ggtcagcctg ctgctggata cctataatat tatggaaagc ggcctgccca acctgatcaa
    19681 gctggacgat tatctcattg agaaataccc caacgatccc aaccgccgtg tcaagagcgc
    19741 ccgcatcgac tccggcgacc ttgcccgcgg ctccaagcgg ctgcgcaagg cactggatgc
    19801 cgccggtaag ccctacatca agctggtggc ctccaacggt ctggatgaga agaaaatcgc
    19861 caacatggag ctgtacgagc acgcacactt cgactcctac ggcgtgggcg aaaacctcat
    19921 cacctccgcc tccgaccccg tgttcggcgg cgtgtacaag ttggtggcag tgaagaagcc
    19981 ggacggcagc tacaccccca agatgaaatg ctccgattct gccagcaagg ccatcatccc
    20041 gggcaagaag atgccgtggc gcctgtacga tgaaaacggt caggcacagt gcgacctgat
    20101 cgccatggac ggcgaggtca tcgaggccgg taagccggtc accatggtca atctggattc
    20161 ggacgccatc gagcgcacca tcacctttat ccccaccgct gtgcgcccgc tgttggtgcc
    20221 gcatattctg ggcggcgagc tggccattga cctgccctct attgcagaaa agaaggccta
    20281 tattgcaaag cagctcaccg aggagacttg ggagagcgag ctgcgtctgg agtgccccca
    20341 caaacactac gtcaacatga cccccgcagt ggccgagtgc cgctcccgga tgtacgccga
    20401 gctgcacgga ggcaaggtgt aagcggcacc gaataagcgg tttttcttga caaaacaggg
    20461 aaactattgt atcataaaag ccgctgattt taataaaaat gttaatacca ccagattgcg
    20521 aatagcagtg tggttgtaat aatttttcct cacacctgtt attcccggct ccctctcaag
    20581 ccagagggca gcagggcttt gtaagccggg gttgcgccgc tgtggtgaaa ttggcagaca
    20641 cgagggactt aaaatccctt tctggagaca gagtacgggt tcgacccccg tcggcggcat
    20701 gtgaaagccc agaatcgttc gttgatccga atgattctgg gctttttctt ttatgctttg
    20761 cggggaacgg gcggggcgct gttgtccgtc agaccaagga tataatcggt actggtatgg
    20821 taaaggtgag caagctggat cagcacctcg gtggggatat cccgcttgcc ggtctcgtaa
    20881 ttggagtagc agacctgtgt gcatttcaga tacgccgcaa catccttttg cagcagatca
    20941 cgatcctccc gcagatcccg gatacgttga tacatggtgt ttacctcaaa ggctttattt
    21001 aaggtaaagt ataggcataa cgaaatgtta tattgacata taaaacaaaa tgttatatca
    21061 tagtatcgcg ccgggaacag ctgtgaatct ccggcgcaaa aggggagagc atcatgaaac
    21121 tggaattccg gcagacggtg acctgcaacc atcttacact tgcaagggtc tgcaaaacga
    21181 tcgactggca gcagccgctg ccccggtgcg gagaatatgt gaccgggctg gatacgctgg
    21241 acggcgagca ggaactgccg gtgcgcaagc tgctgcaccg ggcacaggac ggcagctgcc
    21301 ttgcggagct gccgggcttt aacatcgcgc agctgcggtt ttcttaccgg gagctggagc
    21361 tgttggcagc acaaaagggc tggacgctgc aaaagctgta aaaacttaaa tttccctctt
    21421 gcattctggc caattcgtgc tataatagta aggcaatcgt ttccaaggcc gctcgacggg
    21481 gtagccgata ttgaaggttg tgatgggcac atacattaaa tatggcccca atacgtcaga
    21541 accagaattg aggtgaaaag aatgaaacag ggtatccatc cgaactatgt tgactgcacc
    21601 attacctgcg cttgcggtaa tgtcatcaaa actcgttcca ccaagcccga gatccacgtc
    21661 gaagtt
//
