LOCUS       c00008_gnlPro..        15321 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJDPJMBL_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:42:02
            Original ID  :: gnl|Prokka|KJDPJMBL_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15321
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15321
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1881:5321]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1882..5321
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15321
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15321
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(669..1622)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLKINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1882..2556
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_2"
                     /sec_met_domain="SucD_FumR (E-value: 1e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2595..4538
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.6e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4566..5321
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="Fer2_3 (E-value: 1e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5514..5672
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5645..6676)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLDILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             7057..8316
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.4e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8316..8723
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="HBT (E-value: 2e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 3.1e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8720..9835
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATPVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(10086..10976)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             11584..11946
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11967..13703
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLSGISYFYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13737..15290
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVSDLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 agttctgata gaacttatat ctctttctgt gcatgggcgg tcaaaaaata atcttatttt
       61 tataatattg catatttgtc tgaaagtttt gaggttatgc atattctcat cagcacagaa
      121 cttgattttg tatctgtcga aaaactggga aaagggcaat aggcaatgaa atacaatgcc
      181 tgtgttaatt tatctaattt tagtgcaact ttgttgaagc tcagtagtcg ggatggggtg
      241 atttcttgga tgttttttca tgaacatctg tcactctatc actaaatgtc gtgtgagtct
      301 tgataatcag tgcgtatcta aagtgataga tacctgtttt atatatcacg cttctatcac
      361 tatctgtaat cgctcatcta tctgttttaa atgaataaac tccaagcatt ttaaggtaaa
      421 agtagggaga taattttatc aaccccccca tgtatccgcc cccgacaccc ggatcttacg
      481 ctcttataga tccgggtgtc gggggcggat acatgggggg gttgggtaag ttttattacg
      541 tgtttttcat tgatttttag ctgtatttac ataaaagagc cttgtcttta atgatatagg
      601 agaacaagcc ctttttcctt ttcttgttta ccttgccctg caaattgtca gcttgtttta
      661 gtagaaattc aatcacgttc gaaatcggat agcacttctg ccgtagtagc gttgatgttc
      721 ttgtccaata cataaatgcg gtaagacagg ctcagttctt taccgggctc caatgtgaat
      781 gccttctgct tggtcggtga gaaattccac atgacgtcac cggcaggctt gttgacagtt
      841 ttgtcccata cgcgtaaagg ctcaggatag ttcaggttgg aaggggaggc aacgattagg
      901 atacaggcct tttcgtttcc ggctttccct tggtagtagc accaacgggc tctcgaaccg
      961 tcagcttcgt cgcgggaaag gccttccgag gtgagcattt cggctgtctg atcgttccag
     1021 tcttcgcgcg tacggatgca tatgccgcca taacggtaag cttccatggt gatcgggctg
     1081 gggctggcga ggcggatagt ggtatgatag tcgatgtaat aacctggtaa ggatgttgtc
     1141 ccgatgttga tcttcaggcg ttcgttcatt gctacttttt ctgcgggaga atcggggtag
     1201 accacatggt ccagtgtcgc aacaaaaccg ttgtcggata cgtgttcgaa gttgcggaag
     1261 cgaactgttc cttgtttttt gtggagattc cagaaatcga tctcgtttcc ttcgaacgta
     1321 gttttcgtcc aggcatacca caaaccgaaa tgatggtaat ggtcggcggg agaacaattg
     1381 gtcatcactt cgcctcccaa tgtcttcaaa ggatggatga aaccgctgcg tttatagacc
     1441 gagtcaacgc caggggctgg gtaaaccgtg gtatagttgt aagagaacaa cagtttatct
     1501 cctatcttat agtctaaggt tttccccgtg tcgacgacgg aacaggatgt ttcggaaggc
     1561 tgacaagagc ctaagaacag agaaatcaaa aaaacaccaa tagaaaaaat agcagttttc
     1621 ataatatgac aattaaataa taatcagtta tccggcaaga ccttgcctgt atcggctaca
     1681 aaaaaacgaa attttttcat ttcgcacaat ccgtttgtga tatctgatgc aaataaaacc
     1741 agctagcaag cagcgttcta attgatgaaa tatttcttta atcgtttgcg tgatatgggg
     1801 atttagcata cctttgcacg ataataacca tagattggag gaaatttcta aatacaatta
     1861 aataacttaa attattatct tatgtggtta cttaattctt ctatcgggaa gaagctgata
     1921 atgagtatat caggtctttt tctcattctg ttcttggtgt tccacttatg tatgaacatt
     1981 gcggcagtat tttctggtga agcgtataac gtgatttgcg gtttgctggg ttctaactgg
     2041 tatgctttgc tcggtacatt ggtgttggct gcaggtgtag tcgtgcactt cgtgtatgct
     2101 attatcttga ctctgcagaa tcgtaaggct cgcggtaacg accgttatgc catcaacgct
     2161 cgtccgaaag gtgttgaatg ggcttctcag aacatgtttg ttttgggtgt gatcgttatc
     2221 ctgttcatgg ttctgcactt tactcagttc tggtacaaca tgatgtttgc cgaactggca
     2281 ggtattcatg gtgacattca tccgcaggat ggtgcagcgt ttatcaattt ctacttccag
     2341 ggcaatgttg tgaatacggt gttgtatctg atctggttcg ttgctctgtg gtttcacctg
     2401 actcacggtt tctggtctgc gattcacaca attggctgga acaataccgt ttggttaagc
     2461 cgttgggaat gtatctctaa atgggttgcc actattattt gtggcttatt cgctgttatc
     2521 acagttatct tctacctgaa cggtgtaggt gcttaatttc ggatattatt ttttcaattt
     2581 gaaaataaaa cattatgact caaatagatt ctaaaattcc tcaaggcccg ttggctgaga
     2641 agtggacaaa ttataaaaat caccagaaat tggtgaatcc cgcaaacaaa cgtcgtttgg
     2701 acataattgt agtaggtact ggtctggcgg gtgcttctgc tgctgcctct ctggctgaaa
     2761 tgggattcaa tgtattgaat ttctgtattc aggactctcc ccgtcgtgca cactctatcg
     2821 ctgcacaggg cggtatcaat gcggcaaaga attatcagaa tgatggtgac tcggtttatc
     2881 gtctgttcta cgatacaatc aaaggtggtg actaccgtgc ccgcgaagca aacgtctatc
     2941 gtctggctga agtgtcaaac tctattatcg accagtgcgt agcacagggt gtaccattcg
     3001 ctcgcgaata tggtggtctg ttggataacc gttcattcgg gggtgctcag gtatcccgta
     3061 cgttctatgc ccgtggtcag accggacagc agctgctgtt gggtgcttac tctgcattga
     3121 gtcgtcagat tggtttggga aaggtgaaga tgtacacacg ccatgaaatg ctggatgttg
     3181 tgaaggttga cggacgtgct cgcggtatta ttgcccgtaa tttgattacc ggtaagattg
     3241 aacgttttgc cgctcacgca gtcgttgttg cgacaggtgg ttatgtaaat acattcttct
     3301 tgtctactaa cgcgatggcg tctaacggtt ctgctgcatg gcagtgctac aagaaagggg
     3361 cttactttgc taatccttgt atggtgcaga tccacccgac ttgtgtgcct gtgaaaggtg
     3421 acttccagtc taagctgact ttgatgtcag aatcactgcg taacgacggc cgtatctggg
     3481 ttccgaagaa actggaagat gcgaaggcat tgcaggccgg aacaaaaaag ggaaaggata
     3541 ttcctgaagc agatcgcgac tactatctgg aacgtcgtta tccggcattc ggtaacttgg
     3601 ttcctcgtga cgtggcttca cgtgccgcta aagaacgttg tgatgccggt ttcggtgtaa
     3661 atagcacggg cttggctgta ttcctggatt tctccgatgc tatcaaccgt ctgggtaagg
     3721 aagtggttaa acagaaatat ggtaacctgt tcgatatgta cgaagagatc acgaacgatg
     3781 atccgtacga aactccgatg atgatttatc ctgcattgca ctactcaatg ggtggtttgt
     3841 gggtagacta tgaattgatg acttctattc cggggctgtt cgcaatcggt gaagccaact
     3901 tctctgacca cggcgctaac cgtctgggtg cttctgcttt gatgcaggga ttggctgatg
     3961 gttactttgt attgccttac acgatccaga actatctgtc tgaccagatc caggttccgc
     4021 gcttcagcac tgacctgcct gaatttgtgg aagcagaaaa ggctattaac gcccgtatcg
     4081 cgaagttgat gaacgtgaag ggtaaagaaa cagtcgattc tatccaccgt aagctgggac
     4141 atatcatgtg ggaacacgtc ggtatggcac gcgacgcgga aggcttgaaa gaagctatcc
     4201 aaatgttgaa agacctgaag aaggaattct ggagcaatgt attcattccg ggtgaagcga
     4261 acagcttgaa cgtggaattg gacaaggcat tgcgtttggc tgactttatc gaaatcggtg
     4321 cattgatggc acacgatgcg ttagaccgcg cagaatcttg tggtggccac ttccgtacgg
     4381 aacatcagac cgaagaaggc gaagctatgc gtcatgacga taagttcatg tacgtctctt
     4441 gttgggaata ccagggtgaa gacaaagacc cggttatgct gaaggaagat ttgaactatc
     4501 agttcgttgt tcctcaaaca cgtaactaca agaagtaata atcatcaatc acaaaaatta
     4561 gaatcatgga taaagatata aaggtaacac ttaaagtttg gcgtcagaaa ggtccgaaag
     4621 ataaaggaca gtttgagact taccaaatcg acaaaatcaa tcagagtgtt tctttcttgg
     4681 aaatgttaga cattttgaat gaacgtttgg ttagcgaagg taaagaacct atcgtattcg
     4741 accacgactg ccgtgaaggt atctgcggta tgtgttcatt gtatgtaaac ggacatccgc
     4801 acggaccggc aacaggtgca acaacctgtc agctctatat gcgccgtttc aatgatggtg
     4861 agacgattac gatcgagccg tggcgttctg ctggtttccc ggtaatccgc gacttgatgg
     4921 tagaccgtta tgcttatgat aagattatcc aggcaggtgg tttcgtttct gtaaacacag
     4981 gtggggttcc tgatgctaat gcaattccta tttctaaggc tgatgcggat ttggctatgg
     5041 atgctgctgc ttgtatcggc tgcggtgctt gtgctgctgc ttgtaagaac ggttcagcta
     5101 tgctgttcgt ctctgcaaag gttagccagc tggctctttt gcctcagggt aaggtggaag
     5161 ctgctcgccg tgcaaaagca atggttgcta agatggatga actgggcttt ggtaactgta
     5221 cgaacactcg cgcttgcgaa atggaatgtc cgaagaacat ctccgttagc aacatcgctc
     5281 gcttgaaccg cgagttcatc tctgctaagt tacaagacta atacattata tatgtatgta
     5341 tatggaaaag cccgttgcca atggcaacgg gctttcttta tgttcgttca aacccacaaa
     5401 aaagccgcac tccctataat aaaagtggat gcggcttttt tgttgctttc cagtgaaaca
     5461 gtctctcgat tccctctctg caaagacttt gttaacctta gatctaaaat actatgaaaa
     5521 aaactcactg caaatataaa gtatatttac tgaatacgca agagtttgta attacatttt
     5581 attgcaaatt tgctactttt tgttttaaaa ttgacactgt gtgcggattc acactgttat
     5641 tatatcaaca atcgatcgat tctgacactt gagagtcgct ttgaaatccg tatcctgtat
     5701 gaaatttgtc ggggatggaa tccagaatgt cgaataatgc ttccactgtt tccgcacgta
     5761 gcatggcgac gcgtgtctgc ttgaagtctg caataccttt aaacagcgga gttgcagcca
     5821 aatggcggcg aatgtggaga attccccggc gctcatccaa acgttccacg ctttgttcca
     5881 cctgcttttt cagtatgtcc agataccatg aaaaagattc ggcaggcaat gtctcgcctg
     5941 tatccagata atgcctcact tctctgaaaa tccaggggcg gcctatgctg ccccggccaa
     6001 tcataacggc atccacgcca tattgttcga aacgttgttt gcagatttcg gcggaagtca
     6061 catcgccatt gccgatgatg ggaatttgta tgcggggatt gttttttact tcaccgatca
     6121 gtgtccagtc tgcctctcct gtgtacatct gtgcccgggt acgtccgtgg atggaaaggg
     6181 ctgcgatacc gcaatcctgt agctgttcgg ccaagtctac gatgatccgg ttgtcggcat
     6241 cccagcccaa gcgggttttt acggtgacag ggatgttcac cgctttgacg acttcacggg
     6301 tgatgtccag catcagtgga atattgcgca gcatgccggc gcctgctcct ttgcctgcca
     6361 ctcgtttgac agggcaaccg aaattgatat cgagaatgtc cggatgagcg gcttcgcaaa
     6421 tttgcgcggc ttcgaccatt gtcggaacat cacggccata tatttgtatg gcgaccggac
     6481 gttcttcatc cgccacattc agcttttgct gtgttttatt tacactgcgg atcagggcgt
     6541 ctgctgaaac gaattcggta taaaccatat cggcaccaaa acgtttgcac atcaaccgga
     6601 aagaaatatc tgtaacgtct tccatcggag ctaagaagac ggggcgttcg cctaaatcta
     6661 ttgtacctat tttcatattt atattatcaa tgacggggac aaaggtactg atttcctgct
     6721 aaaaacaggg ataaaaggat atctactaaa aagtgtagta attgatcaat agaaagtaca
     6781 aatgtcatac tgtcaatgat atagataaaa tgataagctg aaatcatgat agttgcatga
     6841 tagtagtatg atagttaaaa atagaaacta tcatgtctta aggtattgaa taacagattc
     6901 taaaggacaa caatgacagt atgatggttg ttttgcaaat ctttatagaa aatggtattt
     6961 gatcacgatt ttgatgctct gagaaacgga tacccatgca attcttctcg gatattattc
     7021 ctacctttgc gaacgaacca gtaaatgtat aagaacttga acgagaaaga ttttgaaata
     7081 atggcgcctg tcggttcgta cgaatcactg atggcggcta tccaaggggg agccgattct
     7141 atctatttcg gtatcgaagg attgaatatg cgttcgcgct cttccaataa ctttacgaca
     7201 gacgatttgc gcaagatcgt tgcgctttgt cgtgagcacg gtattaagag ctatttgacc
     7261 gtcaatacgg ttatttatgg ggaagacctg cctctgatgc gcgagattat cgatgcggcg
     7321 aaggaggcgg aagtttcagc gatcattgcg gccgatgtgg cagctatgaa ctatgccaac
     7381 agcatcggac aggaggtgca tctttccaca cagctcaaca tttccaatgc ggaagcactg
     7441 aaattctatg cccgttttgc tgatgttgtc gtcttggcgc gtgagctgaa tttgaaacag
     7501 gtgcatgaaa tctatcggca gatcgtcgac cagcagatta cgggaccgaa aggagaactg
     7561 atccgtatcg aaatgtttgc ccacggagct ctctgtatgg ccgtttccgg taaatgttac
     7621 ctgagcctgc acgaaatgaa cgcttccgcc aaccggggag cttgcatgca gatttgtcgg
     7681 cgtgcttatt cggtaaaaga taaagacagc aatatcgaac tggatatcga aaaccagtat
     7741 attatgtcgc ctaaagacct taagacaatt catttcatga ataagatgat ggatgcaggt
     7801 gtacgggtat tcaagatcga aggacgtgcc cgcggtcccg aatatgtccg cctggtgacc
     7861 gaatgctata aggaagctgt gcgtgcttat tgcaatggca cgttcgatga aaagaaagtt
     7921 gccgcttggg acgaacgcct gcgcagtgtg ttcaaccgag gattctggga cggctattat
     7981 ttggggcaac ggttgggtga gtggagtagc aaatatggct ccggcgcgac taagaagaaa
     8041 gtgtatgttg ccaaaggaat caaatatttc gacaagatcg gcgtggcgga gttcgaaatg
     8101 gaatccggta acctgaaagt gggtgatgag atcctgatta ccggaccgac aacgggtgcg
     8161 gttatgcaga cgatagaaga aatccgtgtg gacttgaagc cggtggacga gaccgttaaa
     8221 ggtgaacggt tctctctcaa ggtgaacgag aagattcggc cgtctgaccg attgtataaa
     8281 atggaaaagg ttcaacttga aaaggtattt gaataatgaa agagtatatt tttaaactga
     8341 cagacaaggt ccgtgactac gaatgcgacc tgcaaggagt ggtcaacaac tccaattatc
     8401 agcattatat ggaacatact cggcatgaat tcttggagtc gcttggcgag aacttcggaa
     8461 agatgcacga aaaaggggtt gacggatttg tatcgcgggt agaaatccag tataagacct
     8521 cgctcaagag cggcgacagc tatatctctt gcctcaatgt ctataaaaaa ggagtcaagc
     8581 tcgtattcga gcaggatata tatagggctt ctgacaatgc attggcgacg aaaggaatcg
     8641 tcgagtcggt tatcgttgag aacggaaagt tgacacgcgg tgaatatttc gacgaaatgc
     8701 taaaaagaat agaacataca tgactgacaa acggatttac caaatcggcc ttactatgat
     8761 aaacggcgtg ggagatatcc tggcgcgtca tctcctgcag gctttgggag aagcagaggc
     8821 tgtgtttact gaaaagcaac agttgttagg aaggatccct ggtatcggca gcaatattgc
     8881 tgccgaaatc aaacgcccgg aaatcttgca acgggcggaa aaagagttgg cttttatcga
     8941 gaaaaacaat atttcctgtt attatctgac tgatacagat tatccggtgc gcttgagaga
     9001 atgtccggat gcccctatac ttttctattt taagggaaat actaaccttg atgcgacccg
     9061 tatcatcagt attgtgggta ctcgcaacgc gaccgaatat ggtcgagagc ttaccgaatc
     9121 ccttataaaa gacttggcaa aagtgatccc ggacttgttg gtcgtgagtg gattggctta
     9181 cggcatcgat atctgtgccc accggaacgc tttgtacaac cgacttccga ctgttgctgt
     9241 gctggcgcat ggcttggatc gtatctatcc ttcctgccat cggaatacgg ctgtcgaaat
     9301 gctggaatcg ggcggtctgt tgaccgattt tcccagcggt acagaaccag accgtccaaa
     9361 tttcctccgg aggaaccgga ttgtcgccgg aatctcggat tgtacgatcg tggttgaatc
     9421 ggcagaaaaa ggaggctctt tggtaactgc cgatattgca ttctcttatg gccgggatgt
     9481 ctatagcttt ccagggcgtg tcggtgacag ccattccaaa ggatgcaaca atttgatccg
     9541 acaaaataaa gccggcctga tcacttctgc ggacgatctg ctctccgctc tttgttggga
     9601 tatccaagct ggggctactc ccgttcaaac ggagttgttt ttcgccgagg cggaaacatt
     9661 cacctcggaa caaaatccgg ttttagccat tatgcgaacg cggaatgaga tccatatcaa
     9721 cgagcttgcc tcagtgttgg agataccggt acatcaactc tctatgctat tgttcgaact
     9781 ggaaataaac gggaaggtaa aagcgttgcc gggaaatctc tataagctgt cctgaccggc
     9841 tttttcgtat acgatttgta tgtgggagaa gaaacggaac ctctataaac aattaaaggc
     9901 tgtctcacga caacccctaa ccaactttgt taaccttaaa tctaatacta ttatgaaaaa
     9961 accacattgc aaagatacac tcgtcaagag cgtttgtcaa gcattttgtc gctaatactt
    10021 gttaatcaga tgagcataaa tagcaaaaag attttaatcg gctataaaga atcctttaaa
    10081 ctgcgttatt ttgttaaatc gagtccttga aacaggtacg gatagtccgt ttcgatcacg
    10141 tcgggacgag tgctgatctc tgaccggtaa ccggcggttt tctctgtttc cgttttcgcg
    10201 cgatcatgtg tcggagcaac ggaaatcatg cacatgactc cgttacggtg cagagcgtca
    10261 tacagtggtt gctgttcagg cttcatcttc gggcctacat aagccattac ctgtttccag
    10321 gggatgccgg ctttttcata attatcgaat tcttcccgat tcttacacca gcaagaaaac
    10381 atcgcatccg gtttccggtc gagataatag cgggcttgac tggcgttatg taccgtgtac
    10441 atgacgttaa caggcttttc tgtttctata aaatcagcca taacttctaa aggtacatcc
    10501 ttgatatcca aattcaggat tgttttgcct ttgctccatt ccaggcattc ttttaaagtt
    10561 ggaattttga aggctgtcac gttgccgttt cggtccacca gattgaattg ttgcagttct
    10621 gcataagtgt aatctgaaac ctttcctttc ccggtagttg tccggtcgat ggtttcgtcg
    10681 tgcatcaata cgattatccc gtcttttgtc aaacgcggat ctatctcgaa aaacgattcc
    10741 atataggaca aggtcttttc gaatgattcg atgcagttct ccggatagcc gtctagcatt
    10801 ccaccacgat gtccactgat tacaatcggg cgatcgggag cataccggaa ataggcttgt
    10861 agatcccggc tgttcttcac agtaatgtaa tgaggatttt gttctttgtc tgaagccaaa
    10921 agattcccgg ccggcataaa accccctaaa aggagtacca aaataaaaga tagcattttc
    10981 atgatattgt atttatatag attctttgtc aattatgcgg cttaaaagta agactttttt
    11041 atcagtggcg tactataaaa gcactataaa aacatgaaaa tatgacaggc aacaagatgt
    11101 gcaaagaaag aggcaggtat ataaaaaatt aaggattgtc atctcgacaa cccctaacca
    11161 actttgttaa ccttaaatct aatactatta tgaaaaaacc acaatgcaaa aatacactag
    11221 ctaagcttgt ttgtcaagcc ttttacggat aatatatgtt aagctctaat agctattttg
    11281 tcaaaaaatg ttggttattt ataaactata cagattccat gtaaaaactg ctaattcaaa
    11341 tactttttat cgtcggaaaa agtgaaatcc catgcttaaa aagtgtcccc ttggagtata
    11401 taaaatcatt aattaatata ggggatgttt tggtgtggct gcttatagat aaattccttt
    11461 ttggcgcatg cagcgaatag atgatggatt attaattgtt aatacaaatt aacgcattat
    11521 ttcttgcata tttacgatgt attcgtagat ttgcgatacg atcgtaaaaa ataatataga
    11581 aacatggaaa gattaacaag acaggaagag gatgtaatgc gctggatctg gcagatcgag
    11641 ccgtgtttta tcaaagacat cctggcgaag tatgaagagc ctaagcctcc ttatacgaca
    11701 ctcgcttcta ttgtgaagaa tctggaacgt aagaaatacg tgaaagcgaa acgttacgga
    11761 aatacttacg aatacaggcc gctgatccca caggaggaat ataaacggac gtttatggga
    11821 agtgtggtga acaactattt cgagaattct tataaggaaa tggtctcctt ttttgctaag
    11881 gaacagaaga tatcgaccga tgagttgaaa gagattatcg atatgattga aaaaggacga
    11941 gaataaactg ttaaatacat aatgccatga caccggaatt tgcctacttc ttgaaggtaa
    12001 atgtagcttt tatactcctt tatgccttct accggctgtt cttttataag gacaccttct
    12061 ttaaactacg ccgtaccatt ttgttggcat ttttcggggt gtcattgctt tatccgctga
    12121 tgaatattca ggattggatc cgggagcagg ggccgatagt ggaagtcata caaatgtatt
    12181 cagccatttt gcctgaaacg acaataaccc ccggcaatgt tccccaaaca aattggcatg
    12241 atttgttact ttccggtatt tcttattttt attggagcgg tgtaattgcc ttatcgttcc
    12301 gttttttagt acagttgagc agcatcttgt tactggcacg gcggtcggaa gtgactttga
    12361 tccgtaacgt acgtgtacat ctgttgaata aaccggccgg tcctttttct tttttccggc
    12421 tggtatttct gcatcccgac agccattccg agaaagagat cgatgagatt ttggtacacg
    12481 agtgtacgca tgtcagccag tggcattcga ttgacgtgat tatttgcgaa ttggtttgta
    12541 tcatctgttg ggtgaatccg tttgtctggc tgttgaaaag agaggtacgt cataatctgg
    12601 aatatttggc ggatgatacg gtacttgaat cgggctatga cagtcgtagc taccaatatc
    12661 accttttggg gttggcacat accaatagat cggtgacctc tttatctaat aactttaata
    12721 tgctgcatct gaaaaatcgg atcagcatga tgaataagaa acgttcccgg agcataggga
    12781 ggacgaaata cctgattttt ataccgattg tgggcgcctt gctgattttg agcaatgtcg
    12841 atgcattggc ccggatcacg gacgaactga cggaaagcac gtttgccgat gttttactac
    12901 cggaggctat cttgccgttc ccttttgtcg gtgatgcttc tcctgctgaa aaacgtgagg
    12961 agtatgtgct atcggaggaa ggaattgagg ctgccagacg tgcccgtaac caggtgttta
    13021 ccgttgtgga ggtaatgccg gaattccctg gcggacaggg tgctctgctg aaattcctgg
    13081 cgacgaatgt cagatacccg gaatcggccg ttaaaaatgg tatagaggga cgggttagct
    13141 gttctttcgt tgttggaaaa gacggagcta tctcggaggc agaagtgatt cgtggggtaa
    13201 gtccggaact gaatgaggag gctttgcgtg tgataaactc catgccggta tggtcgccgg
    13261 gaaaacagcg tggcaaagcg gttaatgtca aatatacggt accggtaact ttccggcttt
    13321 ccggtggaaa gaaaaaaaca tcctctcgta tcgtgcagag gcagattaaa gaagtcgata
    13381 cgtccggtcg tgtctttacg gtagtgcaac agatgccgga atttccgggt ggacaggctt
    13441 cgttgttgaa atatctggca acacgcataa aatatccggc tattgctcag gagaatggaa
    13501 tacaaggacg tgtctcttgc tctttcgttg tcgacacgga tggaagtttg aaaaatattg
    13561 aagtgatccg tggaatcgat ccttcgctgg acagggaggc tgtccgggtg atccgggaaa
    13621 tgccgaaatg gaatcctggc gtacaaaaca atatggctgt agccgtaaaa tatacggttc
    13681 cggttacttt ccgtttgcag taattgacca gaatcggtca ttaatacgat accattatga
    13741 aatgtaagtt ttctctatta ctgtttcttt gcgtactgtc cctttgggga caggcgcaga
    13801 gtcttaatct tcaggaattg gtcaataaaa aacaatttca ggaagttgta gcacgtgcag
    13861 atagtcttac tcctgccgat tcagccgatt atgctacaat gtcggcaatc gggcaggcgt
    13921 atgaaggact gttgcgctat aaggaggcct atcagtgctt ttctcattgc ttgaagatgg
    13981 atacgaacaa tgtggatgca ttgaatgccg ttgccaggaa tgcgatcaat ttcggaagga
    14041 tagcggaagc taaacaatgt tatcgtaaag tattgggaac cgacagcatg aacttctatg
    14101 ccaactatca gttggcgcgt ctctattatc agttgggaga ttatggtcga gcgacggaac
    14161 actatcatat acttgcttcc atcgaaggtg aaaatccttc tatcctgacc gggctggctg
    14221 attgccatat taaaagaggg accggtccta atacgatgat cgctctttct ttgtatgccc
    14281 gtgctttgga gctgaacccg gaaaatgtgc gtgtggcatc ttctctgata aatacgttat
    14341 tgcggatggg ggacggacag ggagctttgc aggtgtgcga taccgccttg ttctataatc
    14401 cggataacag ccagatacgg cagagtaaag ggatggctct ctatatgacg aaagattata
    14461 agcaggctga ttcagtctat accggtctat tggccgatgg cgattcttct tttttgaatc
    14521 ttaaatatgc gggggcggcc cgctatatgt ccggtcatgc acttgatggg gtcgagctgc
    14581 tggagaaggc ctatgaaata gattcgacgg atgtggaaac agtcatgttg tatggcgctt
    14641 ccctgggaaa aacatacgac cgtaaacggg cttatgagct tttcgatctg gcggaaacga
    14701 atatgcagcc gaaaaaattc ctagttaata tgttgacgac cttccgaggt gatgccttgg
    14761 aaagggacgg ccgttggccc gaagcggaaa agctgtatta tgccgcatgg aaggaagacc
    14821 caacccagtt gcacttcctg tataagatca gtacacaata ctgggatgtc gatccgggac
    14881 tcttccagca ggaggaaaaa ttgcaaaaga cgattttcag tagatacact tacctgacag
    14941 cctatatgaa gacagacaag tcgcaaaagt atctttataa ttaccgccct ttcttggaag
    15001 cggtttgtga agatgccttt ttccggaatg ccgacgaagt gacgatgttg gctcccgatg
    15061 ggaaaaagac aaagttggct gtctccgatc tgcgtgcctt ggtcgcccag ttaccgcaaa
    15121 tgccggaaga tgaacgtctg aggcgcgaga agatgcagga acatattaaa aaagccaggg
    15181 aaaaagaaaa ggaattgcgt aaaagcggtg ctaaactcga tacgcttgcc ctgagtaagg
    15241 aagaaaaaga gaaagcacgg aaaatgttga aagacgccga cttggaatag atagaatatc
    15301 tgaacaatat aatcgatata a
//
