LOCUS       c00016_gnlPro..        16243 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NCOFHCII_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:44:20
            Original ID  :: gnl|Prokka|NCOFHCII_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 26358
            Orig. end    :: 42601
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16243
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[36358:39351]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12993
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16243
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16243
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             932..1846
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_27"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-30, bitscore:
                     98.1, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEYTFSVFTPSYNRAKTLPRLYEALKRQTYRNFEWIIVDDGSAD
                     NTKETVEKFISDRPDFNITYKYQTNKGKHIATNVAAQIAKGEFFITIDSDDSVKDDALE
                     TFINEWNKIPDEDRSKYKGISCRTCNESGKTNGCPLPSERFDCSDLDLRLKYKIDGEMW
                     GMTTLEIIKANPYPCVSGLHFYPENIYWDNIGRKYITRFIDTPLRYYINDQENSLTGNA
                     YSAHRETIFVRLHFINECWDYAKSNPKFFIKQFVGLSRDGLLNGKRFSEIKKMPDTFSK
                     RALAVIFYPMGYFLYKKQSGGSR"
     CDS             1846..2925
                     /locus_tag="ctg16_28"
                     /transl_table=11
                     /translation="MKKVGIVTFHRALNYGAVLQSYALQKTVSSLGAECEIVDYICPKI
                     TADYKPFRIYKNDLLKSFAKSCVMVRRRAKRRDAFKSFFNNYLVKSKKSYTPQNIGELK
                     NDYDLFISGSDQVWSPRCVGFDPAYFLTFADDKQKYSYAASFAVPTLSDEFIDEYKKRL
                     NGFQKFSVREPSGEKLVKELTGRTAETHLDPTLLISADEWKKIAVSKIDKPYILIFTAN
                     PAVSLVDFALKLSKEKNLPVYCINDAPHPVSHGINYIVAPTVEEFVGCFKNAEYVVTNS
                     FHGTAFSVIFNKNLFVEFKNKSGRNIRSEGLLKSLGIDREIVDGNCRETEINWYDVNEK
                     IKNQTIISLDYLKSFVSGD"
     CDS             3101..4864
                     /locus_tag="ctg16_29"
                     /transl_table=11
                     /translation="MYSTIKSIQLLTALLKKYNINKLVLSPGGSDIPIIHSLENDDFFE
                     CHSVVDERSAVYYGIGLAQQTKSPVACICTSGTAVSNYLPGMTEAFYQDVPIVAITADK
                     DPYRLNQLMLQKTQQVNIFESVTKKSVNLPVVRGGNDRWYCERLINEALSELDHHGTGP
                     VHINIPIVENSAVYDCENLPQVRKINRISPDMPSEKWREYAERLSKYKKILVIAGQNNC
                     FSEDDRACVEKFFEKYNCLISVEHMSNLKCKGCLMTYPLSECSMQGMFGELCPDLIISF
                     GNNIASYKLKPMIKAHKEKFVHWQIDTAGRIRDFSDKLTDVFECTPQYFFNCFAENAPQ
                     DSKNDMTYYNMWNDDIKMLDYSSNLPFSNMYVAKKLAEIIPDRSVLHLAILSSTRTMQF
                     FDLKPNVKVYSNIGALGIDGCMSSFFGQASATDELAFCVVGDLSFFYDMNSAGIRGIKN
                     NARIILLNNGGGSEFHFFMGKEKIPTINQYICAEHHKGAKGWIESLGYDYYSATTKEEV
                     DNIIPTLAEESDRPIFVEIFTDMEEDAKLINRLFHDNRMKFGGMKLKMMEKAKSILSPS
                     QIQKAKKLLKK"
     CDS             4879..6063
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) UDPG_MGDP_dh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_30"
                     /sec_met_domain="UDPG_MGDP_dh_N (E-value: 2.2e-37,
                     bitscore: 119.8, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="UDPG_MGDP_dh (E-value: 6.8e-29, bitscore:
                     91.4, seeds: 679, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAGTGYVGLSNAVLLSQKHEVTAVDVVESKVRLINEKKSPI
                     ADREIEEYLADKKLNLVATVDAKSAYKNADFVIISTPTNYDDERHFFDTSSVEAVIELV
                     IECNPNAVIVIKSTIPVGYTKSVIEKYKYTKILFSPEFLREGKALYDNLYPSRIIVGVD
                     MENEELKKSAETFATALADCAIKENIDTLFMDYTEAEAVKLFANTYLAMRVSFFNELDT
                     YAEMKNLNTKSIIDGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLKANFSDVPNDIISA
                     VVTSNKTRKEFITSQIMNKNPKAVGIYRLTMKSNSDNFRQSSIQSVMELLKNNGIELII
                     YEPTLKVDLFEGFGVENDFEKFVTKSDVIVANRYSSVLDCVKEKVYTRDLFFRD"
     CDS             6079..7230
                     /locus_tag="ctg16_31"
                     /transl_table=11
                     /translation="METLIIGKPKIEKLANRARLCSKISENGKPSYILWFDVDAKYADY
                     LTESADAFVVALLPYAMNNSLNISAEAKMSKQLCFQLNEIFIPVLTKNSKLFNKISISA
                     KELTQENYCCKNASATGFSRGVDSFDTICSLSENRTEKLSHLTFFNVGSHRSTANYTPE
                     QSAELYENRLEIAKKSAKIFDMPLIDINSNLGEHLTLPYVKVHHYCSFSAVLCMQKFFK
                     NYYYASGYPISSFSIKQCDTGSAHYEAFTASMLSTESTDFYITGLEKTRLEKVDFISKF
                     PITYDNLNVCYYGENNCGHCEKCVRTQFELMALGKLELYKNVFDIPKFYRDKNKYMDYV
                     LKHQNKDYYAEILSLMKKKGFKLTPIQKIKKAVYAIYLKFREN"
     CDS             complement(7451..7669)
                     /locus_tag="ctg16_32"
                     /transl_table=11
                     /translation="MDKNKKLFYTIIGAISALAAATAAFLALKKHRCAEQKLIEEIDDI
                     VSEKEPEETAKEEPQAEVTADELAEEE"
     CDS             complement(7802..9652)
                     /locus_tag="ctg16_33"
                     /transl_table=11
                     /translation="MKSESIKKFGCVLLSAIMLSGISVCAVSAEEKSTEIHIVHTNDIH
                     GYYKSTSGGQIGFDAVKTIADKENADLILDAGDTFHGQSFATVEEGKSIAELMDAVGYD
                     AMTPGNHDWSYSADRLRELDRESSFTILASNVADTNGNRYFDNNFYIKNVTADDGTKVR
                     VGVFGVIDEDFYTSTSAKNVENVRFENSAETATAYANFLRDDENCDIILALTHNANPEK
                     FIAETSGIDAVIAGHQHILIDKYCTDSDGKSVKLVEANCFFKNVGVLTLTYSNEKGVTD
                     AVEKTYSSADTQGMSDEKIASDISAIEKREQSVLSEVIGESSREYAYSXXXXTSEQEIG
                     RIVTAAYLDFTGADVAMENAGGIRSGIPEGNVTYSDLISISPYGNVLVEKELTGQQIID
                     ILEFSVDLMKKNNAVYDLQKQAIKDGEDPYQYSWPDNSGSVMQFSGLSAVYDYSKPYGG
                     RVSDVKIGGKAIDTLKTYRVVSNNYAFDSSDYGDVASLTTVKEYTTCEQILRDYISNGD
                     FEKAAANANLVEKSSPSEEPTATQEQTVQTAPTGEPATVGTTSVNPTSATGGAATSDST
                     PSQPDKNGSVQTGVTATAVMMLVVILGGVLFALAERKKRI"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 76.2;
                     E-value: 1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_34"
                     /sec_met_domain="Radical_SAM (E-value: 2.9e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDNAVKGFVHSIETFGSVDGPGVRFVIFLSGCAMRCQFCHNPDT
                     WKHDENTVEYTADELLNKALAYRPYWKNKGGITVSGGEPLLQIDFLLDLFKKAKKQGVN
                     TCIDTSANPFTTKEPFYSKWKELMEYTDLLLLDIKHIDNEQHKILTGQPNTNILEMARQ
                     LSDMGKPVWIRHVLVPERNDKDEYLFRLADFIRSLRNVERVEVLPYHTLGVYKWKALGY
                     DYPLEGINPPTKERVKNAEMILNGEKTRD"
     CDS             complement(10756..12993)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_35"
                     /sec_met_domain="Gly_radical (E-value: 4.1e-41, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.1e-271, bitscore:
                     893.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MREEWTNFAGGKWESDIDVRDFIQKNYTPYDGDQSFLEGPTEATD
                     KLWGELKELQKEERAKGGVLDMETEVVSGITAYGAAYLDKDLEKVVGLQTDKPLKRAFM
                     PYGGIKMAEQSCQMYGYTPSPKLHEIFTKYHKTHNQGVFDIYTPEMKLARHNKILTGLP
                     DTYGRGRIVGDYRRVALYGIDRLIEGKKEDFAETNRQGMRRGDFQLREEIADQIRALND
                     MKEMALSYGFDISQPAKNAAEAVQWLYFGYLAAIKTQNGAAMSVGRVSTFLDIYIERDL
                     ENGTLTESQAQELVDHFVMKCRMVKFARIESYNQLFSGDPVWATLEVAGLGIDGRSMVT
                     KNDYRFLHTLENMGPSPEPNLTVLYSSRLPENFKKYAAHISVTTSSIQYENDDVMRPVW
                     GDDYSICCCVSATQTGKEIQFFGARANLAKCLLYAINGGIDEKTKMQVGPEYTPITSEY
                     LDYDEVIKKYDTMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTDVRRTFATGIAG
                     FSHVVDSLSAIKYAKVKVIRDEDGVAVDFETEGDFPRYGNNDERADKIAVDLLKTFMAK
                     LKYCHTYRDSEPTTSILTITSNVVYGKATGSLPDGRKAGEPLSPGANPSYGAEQNGLLA
                     SLNSVAKLPYEYALDGISNTQTINPGALGHNDDERVDNLVNVMDGYFDQGAHHLNVNVF
                     GTEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             complement(13260..13751)
                     /locus_tag="ctg16_36"
                     /transl_table=11
                     /translation="MKTDRVITAMIEYFGSDKKRIHHFLKVYSFAKTIGESENLLPDDQ
                     ELLEISAIVHDIGIKVSEEKYNSSAGKYQELEGPHEAEKLLAALGYEKTFIDKVCYLVG
                     HHHTYGNIDTLPYRILVESDFLVNLYEDDSSRSAAEQAYDKIFRTNTGKNLLKIMFLIP
                     "
     CDS             complement(13869..14393)
                     /locus_tag="ctg16_37"
                     /transl_table=11
                     /translation="MAHPIKHFRTITRHRHKVIANCARAGILRQGLIHDLSKYSPTEFI
                     PGAKYFQGTRSPNEKERELYGYSQAWMHHKGRNRHHYEYWNDYNPKTKQIENVEMPVKY
                     VIEMFCDRVAASKIYNGKNYTDGAPFTYFCRIRGKHRMHPNTEALLEKLLVMLRDEGEE
                     KTFAYIRSMKK"
     CDS             14711..15757
                     /locus_tag="ctg16_38"
                     /transl_table=11
                     /translation="MTFPSKVDSLALKVGESKLIELSSEKAKSVTKWTSSDSKIVTVDD
                     GGRVDALKEGTALISAISKDKSKSEFQVTVAKSTTKKQQSYSTCTTANLDKLENNKRNT
                     AKNLYAIKVNRTANCVTVYTYDEKGKYTIPIRAMICSTGLDNSTITGDYTIGIKSEWLS
                     LVGDVFGRYISGISGDYLFHSVPYYSMSEEDLELEEFNKLGEQASQGCVRLAVSDAKWV
                     YDNCPTGTNVSIYDDAENAGPLGKPDAIKITDFTNKWDPTDSNKKCPYAKATPIISGAN
                     DYTIKSGGEFYALAGVTAVDTCGNDITSNIEVFGNVVTTRKGKYKVTYSVTDVLKRTSS
                     VTITVTVQ"
     CDS             complement(16141..16242)
                     /locus_tag="ctg16_39"
                     /transl_table=11
                     /translation="ILCLCTVVYYVTTLHTLDARLDEIFCLITYVLM"
ORIGIN
        1 cggaagtaaa gatgaacttc aaccttttca gtttcaagct ggtaaaagtt ctgatttccg
       61 caggaatttg gtcgtcaatc ggttatctca gcacagctct gaacagaggt cttgacctgt
      121 taatctgtaa cctgactctc ggagcgggac tcatgggact tttgtcgatt gcaaacaccg
      181 ttccgcactg cattgataac cttattacaa ccattgcaaa tatattcact cccagattta
      241 caatccttta tgcaaaggac aacacggact tacttgttga agaaacaaag ttttcgtcaa
      301 agattatgag ttttctcatg actgcacctc ttgcgggatt tattgcgttt ggcaacaagt
      361 tctatacatt gtggcagccg accaaatctc cggacgaaat taccataatt cagattttgt
      421 cggtgcttgt atgtatttca tacctattta cctgtcacac aagaactctt tctagccttt
      481 tcaccgtatg caacaagctc aaggcctccg ttcttatctc gcttgtgtgc ggtgttctta
      541 cggttattat cgttttactg ctcatacact ttacaccgct cggtgtttat gctattgcag
      601 gcgtcagctc tgtttttatc ggtcttaaag cgatagtatt tgttccgtta tacgccgcac
      661 atattttgaa aataaagctt acaacatatt acaggtctat tttcagagga tggttctgct
      721 ttgctgttgt tatcaccatg ttcatcttta tcaacagctt tgtacacgca aacagctgga
      781 tgtcattcct tcttctctgt gcagcaagcg gactggcagg atatgccgtt tccgttccgc
      841 tcattttctc aagaaaagaa ctcgttctta tcaaggataa aattaagaag aagtttaaga
      901 aaagctaaat tattatcatt ttgaggttgc aatgactgaa tatacttttt ccgtttttac
      961 accgtcatat aacagggcaa aaactctgcc cagattatat gaggcgctga aaagacagac
     1021 atacagaaat tttgaatgga taattgttga tgacggttca gccgacaaca caaaagaaac
     1081 ggttgagaaa ttcatcagcg acagacccga ctttaacata acctataaat atcagaccaa
     1141 caaaggaaaa cacattgcaa caaatgttgc ggcacagatt gcaaagggtg aattctttat
     1201 aacgattgac tccgatgaca gcgtaaaaga cgatgccctt gaaacattta taaacgaatg
     1261 gaacaaaatt cccgatgaag acaggtcaaa atacaaggga atttcgtgcc gcacctgtaa
     1321 cgaaagcggc aaaacaaacg gttgtcctct gccgtcagaa cgatttgact gttccgacct
     1381 tgacctgaga ttgaagtata aaattgacgg tgagatgtgg ggaatgacaa cacttgaaat
     1441 aatcaaagcc aacccctatc cgtgtgtttc gggacttcat ttttatcccg aaaatatcta
     1501 ttgggacaat atcggaagaa aatatataac ccgttttatt gacacaccgt tgcgatatta
     1561 cataaacgat caggaaaatt ctttgacagg taacgcttac tcggctcaca gggaaactat
     1621 tttcgtaaga ctccacttta taaacgaatg ttgggattac gcaaagagca atcctaagtt
     1681 ctttatcaaa caatttgtgg gactttcccg tgacggctta ctcaacggta aaagattttc
     1741 cgaaataaaa aagatgcccg acacattttc aaagagggct cttgcggtca tattttatcc
     1801 catgggatat tttttgtaca aaaaacaatc agggggaagc agataatgaa aaaggtaggc
     1861 attgtaacat ttcaccgtgc attaaactac ggcgctgtgc ttcaaagcta tgcgttgcaa
     1921 aaaaccgttt cctcgctcgg tgcagagtgt gaaattgttg actatatctg tcctaaaatc
     1981 acagccgact acaaaccctt tcgcatttat aaaaacgacc ttctgaaatc ctttgcaaaa
     2041 agctgtgtca tggtaaggag aagagcaaaa cgcagagacg cttttaagtc gtttttcaat
     2101 aactatcttg taaagagtaa aaagtcgtat actccgcaga atatcgggga gcttaaaaac
     2161 gattatgact tgttcatttc gggaagcgat caggtgtgga gtccgagatg cgtcggtttt
     2221 gatcccgctt attttctgac atttgccgat gacaaacaga agtattcata tgcggcaagc
     2281 tttgccgttc cgacattgtc cgatgaattt attgatgaat ataaaaaaag gctgaacggt
     2341 tttcagaagt tctcagttcg tgaaccgagc ggagaaaagc ttgtaaaaga actcacgggc
     2401 agaaccgccg aaactcatct tgatcctacc ctgctgattt cggcagacga atggaaaaag
     2461 attgccgttt caaaaattga caaaccgtat atcctcattt ttacggctaa tccggcagtt
     2521 tcgcttgtgg attttgccct taaactgtca aaagaaaaga accttcccgt ttactgcata
     2581 aacgatgcac ctcaccctgt aagtcacggt ataaattata ttgttgcacc tactgttgag
     2641 gaatttgtcg gctgtttcaa aaatgccgaa tatgttgtta caaactcgtt tcacggaaca
     2701 gcgttttctg ttattttcaa caagaatctt tttgttgaat tcaagaacaa aagcggaaga
     2761 aacatccgct ccgaaggtct tttgaaaagt cttggaatcg accgtgaaat tgttgacgga
     2821 aactgccgag aaaccgaaat aaactggtac gatgtgaacg aaaaaatcaa gaaccagaca
     2881 ataatatctt tggattatct taaatccttt gtcagcggtg attaaattga gtcttaaaaa
     2941 tacactaaaa aaagtcagac agagcataat caaaaccttt aaagcaaaaa atgttgttcc
     3001 cgtgtatgta cagaaggaga acaacaatat tcttgacggc aaaaccgctc tgattacagg
     3061 cggttccgga attatcaaaa actaaagcgg aggaaagcgt atgtattcta caataaaaag
     3121 catccagttg ctcactgcac ttctgaaaaa atataatatc aacaaattgg tgctttctcc
     3181 cggaggcagt gatataccta taattcattc acttgaaaat gacgattttt ttgagtgtca
     3241 ttcggtcgtt gacgagagaa gtgccgtgta ttacggcatc ggacttgcac aacagacaaa
     3301 atcccccgtt gcctgtatct gtacctcggg tacggctgta agcaactatc ttccgggtat
     3361 gacagaggca ttttatcagg atgttccgat tgtcgcaatt accgctgaca aagacccgta
     3421 cagattaaat cagcttatgc tgcagaaaac ccagcaggtc aatatttttg aatcagttac
     3481 aaaaaaatcc gttaatcttc ccgttgtgcg tggcggaaat gacagatggt actgcgaaag
     3541 acttattaac gaggctcttt cggagcttga ccatcacgga acaggacctg tgcatatcaa
     3601 tattccgatt gttgaaaact cggctgtata tgattgtgaa aatcttcctc aggttaggaa
     3661 aatcaacaga atttctcccg atatgccctc cgagaagtgg cgtgaatatg cagaaaggct
     3721 ttcaaaatat aagaaaattc ttgtcattgc cggtcagaac aactgtttct cggaagatga
     3781 cagagcgtgc gttgagaagt tctttgagaa atacaattgc cttatatcgg ttgagcatat
     3841 gtcaaacctc aagtgcaagg gctgccttat gacctatcct ttgtcagaat gctcaatgca
     3901 gggaatgttc ggcgagttat gccccgatct tattatttcg ttcggcaaca atattgcttc
     3961 atataaactc aagcctatga ttaaggctca caaggaaaaa tttgttcact ggcaaattga
     4021 tactgcggga agaatcagag atttttccga caagctgaca gatgtatttg aatgtacacc
     4081 gcagtatttc tttaactgct ttgcagagaa cgcaccgcag gattcaaaaa atgatatgac
     4141 atactacaat atgtggaatg acgatatcaa aatgcttgat tattcaagca atcttccgtt
     4201 ctcaaatatg tatgttgcca aaaagcttgc tgaaattatt cccgaccgtt ctgttctgca
     4261 ccttgcaatt ctcagcagta caagaactat gcagttcttc gatttgaaac cgaatgtcaa
     4321 ggtttacagc aatatcggcg ctctgggtat tgacggctgt atgtcttcgt tcttcggaca
     4381 ggcatcggca acagacgagc ttgccttttg cgttgtgggc gacctcagtt tcttctatga
     4441 tatgaactcc gcaggcatca gaggaatcaa gaacaatgcg agaattattc ttctcaacaa
     4501 cggcggtggt tcagaatttc acttctttat gggcaaggaa aagattccta caatcaatca
     4561 gtacatctgc gccgaacatc acaagggcgc aaagggctgg attgaatcac tcggatatga
     4621 ctattacagc gcaacaacca aggaagaagt tgacaacatt attcctacac ttgcagaaga
     4681 atccgaccga ccgatttttg ttgagatttt caccgatatg gaagaggacg caaagcttat
     4741 taacaggctt tttcatgaca acagaatgaa atttggcgga atgaagctca agatgatgga
     4801 aaaagcaaag tcaattctca gtccgtcaca gattcaaaag gcaaaaaaat tattaaaaaa
     4861 gtaatcaggt gaaaccaaat gaaaatagca attgccggga caggctatgt aggtctttca
     4921 aacgctgtac ttctttcgca gaaacacgag gtaaccgctg ttgatgtcgt tgaaagcaag
     4981 gtaaggttaa tcaatgaaaa gaaatctccg attgccgaca gggaaatcga agaatatctt
     5041 gctgacaaaa aattaaattt ggttgcaacc gttgatgcaa aatctgcgta caaaaacgct
     5101 gattttgtaa ttatctctac tcctaccaat tacgatgacg aaagacactt ttttgataca
     5161 tcgtccgttg aggctgtaat tgagcttgta attgaatgca acccaaatgc ggttatagtt
     5221 atcaaatcca ctataccggt tggatacaca aaaagtgtta ttgaaaaata caaatacaca
     5281 aaaattcttt tcagtcccga atttttgcgt gagggcaagg ctctctatga taacctctac
     5341 ccgtcaagaa tcattgtcgg tgttgatatg gaaaatgaag aactgaaaaa atctgccgag
     5401 acttttgcaa cggcacttgc agactgtgca attaaggaaa acatagacac tctctttatg
     5461 gactacacag aggcagaggc ggtcaagctt tttgcaaata cataccttgc aatgcgtgtc
     5521 agctttttca acgagcttga cacatatgcc gaaatgaaga accttaacac taaaagtatc
     5581 attgacggtg tgtgtcttga tccgagaatc ggaaatcact acaacaatcc gtcctttggc
     5641 tacggcggtt actgtctgcc aaaggacaca aaacagctca aggccaattt ttcggatgtt
     5701 ccgaatgaca ttatcagcgc tgttgtaaca tctaacaaga caagaaaaga atttattaca
     5761 tcacagataa tgaataaaaa tccaaaagct gtcggaattt accgccttac aatgaagtca
     5821 aattccgata acttcagaca aagctcaatt cagagcgtta tggagctttt gaaaaataac
     5881 ggtatcgagt taatcatcta cgaaccgaca cttaaagtcg atttattcga gggctttggc
     5941 gttgaaaacg actttgaaaa gttcgtcaca aaatcggatg taatcgttgc aaacagatac
     6001 agctccgttc ttgactgtgt aaaagaaaag gtttacacaa gagatttgtt tttcagagat
     6061 taatttgagg gtaaaagtat ggaaacattg attatcggca aaccgaaaat tgaaaaactt
     6121 gctaatcgtg ccagactctg ttcaaaaatc agcgaaaacg gaaagccttc ctacattctc
     6181 tggtttgatg ttgatgcaaa gtatgctgac tatctgaccg aaagtgccga cgcattcgtt
     6241 gttgcgctgt tgccgtatgc aatgaacaac agtctaaata tttcggcaga agcaaagatg
     6301 tcgaagcaac tgtgttttca gcttaatgaa attttcattc ccgttcttac aaaaaattca
     6361 aaattattca acaaaatttc gatatctgca aaagagctta cacaggaaaa ctactgctgc
     6421 aaaaatgcgt cggcaacagg attttcgaga ggtgtggatt catttgacac aatttgcagt
     6481 ctttccgaaa acagaacgga aaagctgagt catcttacct ttttcaatgt cggctcccac
     6541 aggagtacgg ctaattacac acccgaacaa tctgccgagc tgtacgaaaa tcgtcttgaa
     6601 attgcaaaaa aatccgcaaa aatctttgat atgccgttga ttgacattaa ttcaaatctc
     6661 ggtgaacatc ttaccctgcc gtatgtaaag gttcatcatt attgcagctt ttcggcggtc
     6721 ttgtgtatgc agaaattttt caaaaactat tactatgcgt cgggataccc gataagcagt
     6781 ttttcgataa aacaatgcga caccggctcg gcacactatg aggcatttac ggcaagtatg
     6841 ctgagtaccg aaagtaccga tttttacatt acaggtcttg aaaaaacaag gcttgaaaag
     6901 gttgacttca tttcaaaatt tccgattaca tatgataacc tcaatgtgtg ttactacggt
     6961 gagaacaact gcggtcactg tgaaaagtgc gtcagaacac aatttgagct tatggcactc
     7021 ggaaaacttg aactgtataa gaatgttttt gatattccga aattttacag ggacaaaaac
     7081 aaatatatgg actatgttct caaacatcag aacaaggact attatgcaga aattctcagt
     7141 cttatgaaaa agaagggttt caagcttacg ccaattcaaa aaattaaaaa ggctgtctat
     7201 gccatttatc ttaaattcag agagaattaa ggcttacggt tacttcgcac aaaacaaaaa
     7261 tgcatcagac cttttcgggc aactgatgca ttttcttttt taaactgttt tcttgaatag
     7321 actgcggtgg cacaccgccg acatcatttt ctgttttcaa ctttcaattc ttaattgaaa
     7381 gcaccgctcg ggtatttaac ttttgcacat gcaaatactg ctacccgaat tgggtgcaac
     7441 aacttgttgc ttattcttcc tcagcaagct catcggctgt aacttctgcc tgcggttctt
     7501 cctttgcagt ctcctcaggc tctttttcgg aaacaatatc gtcaatttcc tcaataagct
     7561 tctgttctgc gcatctgtgc ttttttaaag cgagaaatgc tgctgtggca gccgcaagtg
     7621 cagagattgc accgatgatt gtgtagaata attttttgtt tttatccatt ccggcacctc
     7681 tttcagtatt aatataaatc agcggaaaaa ccgtattttt ctacttattg ctattttata
     7741 tcatttttac aaatttttca ataggcaact gataatcttt gcacaaatgg ctgtcagtgt
     7801 gttatattct ctttttacgc tctgcaaggg caaaaagcac tccgcccaaa attacaacaa
     7861 gcatcataac agccgttgct gtcactcctg tctgaacgct gccgttttta tcaggctgtg
     7921 aaggagtgct gtccgatgtt gcggcaccgc ctgttgccga agtcggattt acggatgttg
     7981 taccgacagt tgcaggctca cccgtcggag cagtctgaac agtctgttcc tgagtagcag
     8041 tcggttcttc cgacggtgac gatttctcaa caagatttgc atttgcggca gccttttcaa
     8101 aatcgccatt gctgatataa tcacgcagaa tttgttcgca ggtggtatat tctttcacgg
     8161 tcgtgagcga cgcaacatcg ccgtaatcgg aactgtcaaa cgcatagtta tttgaaacca
     8221 ctctgtaagt ttttaaagtg tcaattgcct ttcctccgat ttttacatct gacactctgc
     8281 cgccgtacgg ctttgaatag tcatataccg cacttaaacc gctgaactgc attacagaac
     8341 cgctgttatc cggccagctg tactgatacg ggtcttcccc gtcctttatc gcctgctttt
     8401 gaaggtcata aaccgcattg tttttcttca taaggtcaac tgaaaattca agaatatcaa
     8461 taatctgctg acctgtaagc tccttttcaa caagcacatt gccgtagggt gaaattgaaa
     8521 tcaaatcgga atatgtcaca ttaccctctg gaatacccga acggattccg cctgcattct
     8581 ccattgcaac atcagcaccc gtaaagtcaa gataagcggc tgttacgatt ctgcctatct
     8641 cctgctcgct tgttcnnnnn nnnnngctgt aagcgtactc cctactgctc tcgccgatta
     8701 cttcgctgag tacgctctgt tcacgctttt caattgcaga aatatcggac gcaatctttt
     8761 catcggacat cccctgagta tcggcagacg aatatgtttt ttcgactgca tcggtaacgc
     8821 ccttttcatt ggaatatgtc agagtaagca cacctacatt tttgaaaaag cagtttgcct
     8881 caacaagctt tacgctcttg ccgtcactgt cagtacagta tttgtcaatg agaatgtgct
     8941 gatgacctgc gattaccgca tcaatgcccg atgtttcggc aatgaatttt tcggggtttg
     9001 cattatgagt cagcgcaagt ataatatcac aattctcgtc atctctgaga aaattcgcgt
     9061 acgctgtcgc tgtttcggct gaattttcaa agcgaacatt ttcaacattc tttgccgatg
     9121 ttgatgtgta aaaatcttcg tcaataacgc cgaaaactcc gactcttacc tttgtgccgt
     9181 catcagcagt aacattcttt atataaaagt tgttgtcaaa atatctgttg ccgtttgtgt
     9241 ctgccacatt tgaggcaagt atggtaaaag agctttctct gtcaagctct ctcagcctgt
     9301 cggcactgta tgaccaatcg tgattgccgg gcgtcattgc gtcataacct acagcgtcca
     9361 taagctcggc aatgcttttt ccctcttcaa cggtggcaaa tgactgtccg tgaaaggtgt
     9421 cgcctgcatc aagtatcaaa tcggcatttt ccttgtccgc aatggtcttg actgcgtcaa
     9481 aaccgatttg accgcccgat gtggacttgt agtagccgtg aatatcgttt gtgtgaacta
     9541 tatgaatttc cgttgatttt tcttcggcag atacagcaca caccgaaatg cccgaaagca
     9601 ttatggcact aagcaaaaca caaccgaatt tttttatgct ttctgatttc attactttac
     9661 tcctttcaaa ttataaatat gtagtaattg tttgtaaaat caatgctttg ttgggtgaat
     9721 tgtaccatat tctgcgcaat ttttcaatag ttttatattg gatacggtgg caagctgttt
     9781 tattattgca aaattctgct ttatctgcta ttattctaag atgttgataa cccaaaagtt
     9841 acgctgagat ttctcaacaa ggacagctta aaaatctttg aatacacctt tgattcatca
     9901 attttgctga agaaaaaaca acaaaagcag aataacaaat aaaaatcaaa acaaaaacgg
     9961 cagtaccaaa aaatcggtac tgccgttgtt atataagaaa ttaatctctt gttttttcgc
    10021 cgttaagaat catttccgca ttcttaacac gctcttttgt cgggggatta atgccctcga
    10081 gaggatagtc ataaccgaga gccttccact tgtacacacc gagtgtgtga tacggaagaa
    10141 cttcaactct ttcaacattc ctgagcgaac ggataaagtc ggcaagtctg aaaagatact
    10201 cgtccttatc atttctttca ggcacaagaa catgtcttat ccatacgggc ttgcccatat
    10261 cggaaagctg tcttgccatt tcaagaatat tggtgtttgg ctgtcctgta aggattttgt
    10321 gctgttcgtt gtcgatatgc tttatatcaa gcaacagcaa atccgtatat tccattagct
    10381 ctttccactt tgaatagaac ggctctttgg ttgtaaacgg gttggcgctc gtgtcaatac
    10441 aggtattaac gccctgcttt ttagccttct tgaacaaatc aagcaaaaag tcaatctgta
    10501 aaagcggctc acctccgctt actgtgatac cgcccttatt tttccaatag gggcggtatg
    10561 caagcgcttt attaagcaac tcgtcggcgg tgtattccac ggtgttttca tcgtgtttcc
    10621 atgtgtcggg attgtggcag aactggcaac gcattgcgca accgctcaga aaaatcacaa
    10681 atctcacacc cggaccgtca acagagccaa aagtttctat tgagtgtaca aagcctttaa
    10741 cagcgttgtc cgacattaca ttctgtcgtg gcaggttctg gcaataacat ccagctgctg
    10801 ctctcttgta aggtcgatga acttaacagc ataacccgat acacggattg tgaagttagc
    10861 gtactcttcc ttctcaggat gctccatagc gtcaatgagt ttttctgtac cgaatacatt
    10921 tacattgagg tggtgtgcgc cctgatcaaa gtagccgtcc ataacattta cgaggttgtc
    10981 aacacgctcg tcatcgttgt gtccgagagc acccgggtta attgtctgag tatttgaaat
    11041 accgtcaaga gcgtactcgt aaggaagctt agcaacagag ttaagtgaag caagaagacc
    11101 gttctgctct gcaccgtagc ttgggttagc acccggtgaa agaggctcgc cggcttttct
    11161 gccgtcagga agtgaacctg tagccttacc gtaaacaaca tttgatgtga ttgtaaggat
    11221 agaagttgta ggctctgaat ctctgtatgt gtggcaatac ttgagcttag ccatgaatgt
    11281 cttgagaaga tcaacggcaa tcttatctgc tctctcgtca ttgttaccgt atcttgggaa
    11341 gtcgccctct gtttcaaagt caacagcaac gccgtcctcg tcacggataa ccttaacctt
    11401 agcgtactta atagcgctga gtgagtcaac aacatgtgag aagcctgcaa tacctgttgc
    11461 aaatgttctt cttacatctg tatcgataag agccatttct gctgcctcat agtagtactt
    11521 atcatgcatg tagtgaatca tgttaagtgt gcctacatag aggtgagcaa gccaatccat
    11581 cattgtgtca tacttcttga taacttcgtc ataatcaagg tactctgatg tgataggtgt
    11641 atattcagga ccaacctgca tctttgtctt ttcatcaata ccgccgttga tagcgtagag
    11701 aaggcactta gcaaggttag ctcttgcgcc gaagaactgg atttccttac ctgtctgtgt
    11761 tgcagatacg cagcagcaga ttgaataatc atcgccccat acaggacgca ttacatcatc
    11821 gttctcgtac tgaattgagc ttgttgtaac tgaaatatga gcagcatact tcttgaagtt
    11881 ctccggaagt cttgaagaat aaagaactgt gaggtttggc tcaggtgaag gtcccatatt
    11941 ctcaagtgtg tggaggaaac ggtagtcgtt ctttgtaacc attgaacggc cgtcaatgcc
    12001 aagacctgca acttcgagtg tagcccatac agggtcgccc gagaagagct ggttgtaaga
    12061 ctcaattctt gcaaacttaa ccatacggca cttcataaca aagtggtcaa cgagttcctg
    12121 agcctgtgat tctgtaagtg taccgttctc aaggtcacgc tcgatgtaga tgtcgaggaa
    12181 tgttgataca cgaccaacgc tcattgcagc gccgttctga gtcttgatag cagcaagata
    12241 accgaagtag agccactgaa ctgcctctgc agcgttctta gcaggctgtg aaatatcaaa
    12301 gccgtaagaa agtgccattt ccttcatatc gttaagagca cgaatctgat cagcgatttc
    12361 ttcacgaagc tggaagtcgc ctcttctcat accctgacgg tttgtttctg caaagtcctc
    12421 tttcttgcct tcgataagac ggtcaatacc gtaaagagca actcttctgt agtcaccgac
    12481 gattctgcct ctgccgtatg tgtcgggaag acctgtaaga atcttgttgt gacgggcaag
    12541 cttcatctcg ggagtataga tatcgaatac accctggttg tgagtcttgt gatattttgt
    12601 aaagatttcg tggagtttag ggcttggagt gtagccatac atctggcatg actgctcagc
    12661 cattttgata ccgccgtaag gcataaatgc acgcttgaga ggcttgtctg tctgaagacc
    12721 tacaaccttt tcaaggtctt tatcaagata tgcagcgccg taagctgtga tgccgcttac
    12781 aacctcagtt tccatatcaa gaacgccgcc cttggctctt tcttccttct ggagttcctt
    12841 gagctcgccc cagagcttgt ctgtagcttc tgtaggacct tcaaggaaag actggtcgcc
    12901 gtcataaggt gtgtagtttt tctgaatgaa gtctctgaca tcaatgtcgg actcccattt
    12961 gccacctgca aaatttgtcc attcttctct cattactgta aaacctccga taatgataat
    13021 taatactgaa ttttgtatat gacacaaaaa aatgccgact caattccaag cagacgcccg
    13081 gtaaggtcag ctccttgaaa aaatcgtcat acatccttgt attctgtcat ttattcactt
    13141 ttataatcat ataaccaaca ccattaaaat aacacttttt aagggcgttg tcaagcattt
    13201 tgggatactt tttacaccac tttttcacgc tcaaaacact atggtaaatg agtacaattt
    13261 tagggtatga ggaacattat tttcagcaga ttttttcctg tatttgtgcg gaatattttg
    13321 tcatatgcct gctctgctgc actgcggctt gaatcgtcct cataaaggtt cacaaggaag
    13381 tctgactcta ccaaaattcg gtacggcaaa gtatcaatat ttccataggt gtgatggtgt
    13441 cccacaaggt aacaaacttt gtcaataaat gttttttcgt aaccgagagc ggcaagcaac
    13501 ttttcagcct cgtgaggacc ttcaagttcc tgatactttc ctgcagacga attgtacttt
    13561 tcttcgctca cctttatgcc gatgtcgtga acgattgcgg agatttcaag aagctcctga
    13621 tcgtcgggca aaagattttc actttcaccg attgtctttg cgaatgaata aaccttgaga
    13681 aaatggtgaa tccttttctt gtcacttcca aaatattcaa tcatagcagt tataaccctg
    13741 tcggttttca tattatcact ccttacggcg agccgccgta ccctattcgt gtagatagtt
    13801 tttgtttgtg caattctgta ggggtagcct tgcgactata tttcagacgg gaggattcgc
    13861 acaaacaatc actttttcat acttcttata tatgcaaagg tcttttcttc accctcatct
    13921 ctcagcataa ccaataattt ttcaagcaaa gcctcggtgt tggggtgcat acggtgtttg
    13981 cctctgattc tgcaaaaata tgtaaacgga gcgccgtccg tgtaattttt gccgttgtag
    14041 attttgcttg cggcaactcg gtcgcagaac atttcgataa catattttac aggcatttca
    14101 acattttcaa tctgctttgt ctttgggtta taatcgttcc agtattcgta atggtgacgg
    14161 tttctgccct tgtgatgcat ccacgcctgt gaatagccgt acagttctct ttccttttca
    14221 ttgggacttc tcgtgccctg aaaatacttt gcacccggaa taaattctgt aggcgaatac
    14281 tttgacaaat cgtgtattaa tccctgtctg agaattcctg cccttgcaca gttggcaatt
    14341 accttgtgcc tgtgacgggt tattgttctg aaatgtttaa tcggatgtgc cataattatc
    14401 accataaatt gttagtttgg aaaatacaaa acattctccg actgacattt taccacattt
    14461 cttgccgatt taaaatagca cttgcaagat tgtcgaaaaa aagttataat atacaaaggt
    14521 taaaattttg taaccattta atgttaaatt ctataaggat aggtaatcta tgaaaaagaa
    14581 aattttcatt cttttacttt gtgttgtcct cattgcaacc tgcatattat gcggtgtaac
    14641 gggaattttc ggaaatgatt ctcaaaattc tccaaaaccg cagacgcccg atacggcagt
    14701 aaccgaaaat atgacatttc cgagcaaggt cgattcgctc gcattaaaag tcggcgaatc
    14761 aaagcttatt gaactgtcat cagaaaaagc aaaatctgtt accaaatgga caagctcgga
    14821 cagtaaaatt gttaccgttg atgacggcgg aagggttgac gctctcaaag agggtacagc
    14881 tctgatttct gcaatttcaa aagacaaatc aaagtcggaa tttcaggtta cggtggcaaa
    14941 atcaaccacg aaaaaacagc aaagctactc aacctgtaca acggcaaatc ttgacaagct
    15001 tgaaaacaat aagcgtaaca cggcaaaaaa tctgtacgca atcaaggtca accgcacggc
    15061 aaactgcgtg acggtttaca catatgacga aaagggcaag tacacaatcc ccataagggc
    15121 tatgatttgc tccacaggtc ttgacaattc gacaatcacg ggtgactaca caatcggaat
    15181 caagtccgaa tggctttccc ttgtgggcga tgttttcgga agatacatca gcggaatttc
    15241 tggcgattat cttttccact ccgttcccta ctactcaatg agcgaagaag atttggagct
    15301 tgaggagttc aacaagcttg gcgaacaggc gtcacaagga tgcgtaagac ttgcggtttc
    15361 ggatgcaaag tgggtttatg acaactgccc cacaggcaca aatgtaagca tatatgacga
    15421 cgcagaaaat gcaggccctc tcggaaaacc ggatgcaatc aaaatcaccg attttaccaa
    15481 caaatgggat ccgacagaca gcaataaaaa atgcccgtat gccaaagcaa caccaataat
    15541 cagcggtgca aacgattaca caatcaaaag cggcggcgaa ttttacgccc ttgcaggagt
    15601 aacagccgtt gacacctgcg gcaacgacat aacatcgaat atcgaagttt tcggcaatgt
    15661 agtaaccacc cgaaaaggca agtacaaggt aacatattca gtcaccgatg tgcttaaaag
    15721 aacatcaagc gtaacgatta cggtaacggt gcaataaaca tggtgcgcca ctgttctccg
    15781 agcggagctt ttaaattgaa agtggaaaat tgaaaatgta aaataaaaat gcggttggca
    15841 atgtgccacc gcatttttta tgttcgtgtg ttcgtgcaga cggttttaat agtaaattac
    15901 aaatgttgcc cgagcataac atagtaattg tttgtacata cagtagcggc ggtcagtgaa
    15961 cgccatttga tttggttgca aagccaaatc aaccacacag caacatacat attttgacca
    16021 agtataaaat tccaattatt tttgcaatgt atgttgtagt ggcgaaccgt gttcgcgccc
    16081 gttcgtatgc aacgcatacg attgcacgca atgcgtgcaa ggttcaatac acaattataa
    16141 tcacatcaaa acatatgtga ttaaacaaaa tatttcatca aggcgggcgt ccaatgtgtg
    16201 cagtgtagta acatagtata caacagtgca aagacatagt ata
//
