LOCUS       c00061_gnlPro..        11119 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MFAJOCNA_61.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:20:10
            Original ID  :: gnl|Prokka|MFAJOCNA_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11119
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11119
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7505:10449]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7506..10449
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..11119
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11119
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             2..478
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="YPIIKEEKVEPEVYRVINAILETEQSDITVAQAYLQIVLARCIGK
                     LNLVEKSNVGSNDLIYQTVSYISANFKKKFSLEEMAKDLGVSKYVLSRLFSKTFHRNFN
                     QYLNDARLNYACHRLENTSDSITNICLDSGFESQRXXXXKKDIKYHRVTTGVHV"
     CDS             965..1813
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="ATP_bind_3 (E-value: 6.8e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLCEAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             1810..3597
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="Peptidase_M24 (E-value: 4.3e-43, bitscore:
                     136.5, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDGIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGENFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSARERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(3685..5451)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.7; E-value: 1.8e-86)"
                     /gene_kind="resistance"
                     /locus_tag="ctg61_4"
                     /transl_table=11
                     /translation="MSRLTIKDPAKSKSSETFLKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGTFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNFGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(5448..7262)
                     /locus_tag="ctg61_5"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNGYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDVNQIQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             7506..8777
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_6"
                     /sec_met_domain="HGD-D (E-value: 2.3e-56, bitscore: 180.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERTFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             8770..10449
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_7"
                     /sec_met_domain="HGD-D (E-value: 1.1e-17, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 7.4e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(10672..11118)
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="LKDGSYENIATNLPRDEFKTEDFEMLYHLRWSEENSFRDLKYSLC
                     LKAFHSKKYAYIVQEVWARVILYNFSSSIIINVTIKREDCAYEYQANYSSALKTCRDFL
                     RIHDGTTKINVESLIAQNIEPIRPGRTFARQHRFKLPMSFCYRH"
ORIGIN
        1 atacccaatc atcaaagagg aaaaggttga accggaggta tatagggtta taaatgcaat
       61 tttagagaca gaacagtcgg atattactgt tgcacaggca tatcttcaaa ttgtgttggc
      121 acgctgcata ggaaaattaa atttggtaga aaagagtaat gtggggagca acgatcttat
      181 ttaccagaca gtttcctata tatcagcaaa ttttaagaag aagttttctc tggaagagat
      241 ggcaaaagat ctgggggtga gcaaatatgt tttatccaga ctcttttcca aaacattcca
      301 tagaaacttt aatcaatatc ttaacgatgc aaggctgaac tatgcatgcc atcgtttgga
      361 aaatacgagt gattctatta caaacatttg tctggatagt ggatttgaaa gtcagagaan
      421 nnnnnnnnna aagaaagata taaaatatca ccgagtgact accggagtac atgtctgaaa
      481 gatatgttgt cataacatat agattaataa attcaataaa aatctgatta tcagtctgaa
      541 ataagtatct ctgggtgtta tttataatat ggggtagtgg ttaattatta tgtcatgtat
      601 gaatggagaa gaaacaaacg gagaactgct tcagaaaaag aagtagacaa actgtaaata
      661 aagaagttaa gagaggctgt tactttagaa actatttaaa gaagtaatag aagtcgggga
      721 agcgttagaa aagatacaag aaacataaat caatattgtt cgttctattt tcagtaacac
      781 atttcgcaat gcgaaaaata ggttgctgaa cagtcgttgc ctatattata atgaagctat
      841 agcaccctgt taaataatac atttgagaaa gttcaacttt cacgctttgt tgagccagat
      901 caatatacat tatttacgag gagtgctaca ggtacaataa aaaacggaca agaggcagac
      961 tgatatggaa aataaactag aacatttaaa agaatatctg aagggacttg gcagtgtagc
     1021 agttgctttc tcaagtggag tggattctac attcttatta aaagtagctc atgatgtgct
     1081 gggtgataag gcgattgcga ttacggctca atcctgttct ttcccgaaaa gagagctgaa
     1141 tgaagcgaag gcattctgcg agaaagaggg gattcagcat gtgatctgcc agtctgagga
     1201 attggagatt gaaggatttt caaagaatcc tccgaacaga tgttatttat gtaaaaaaga
     1261 actgtttgag aagattggcg atattgcaaa aaagaatggg attgaatata ttgcagaggg
     1321 atcaaatatg gatgataacg gcgattacag accaggtctg atcgccgtaa aagaacttgg
     1381 agttaagagc ccgctatgtg aggcgaagct gacgaaagcg gagatcagag aatactcaaa
     1441 ggaactgggg cttccgactt gggacaaaca gtcatttgcc tgtctgtcct ccaggtttgt
     1501 ctatggagag accatcagtg aggaaaagct tggaatggtt gagaaagcag agcagctttt
     1561 acttgactat ggattccatc aggtacgtgt ccgtattcac ggttcacttg caagaattga
     1621 gatcatgccg gaggaatttc cgaaacttct ggaaaaaaat gtccgagagg atattgcaaa
     1681 gaaatttaag gagtatggat tcacttatgt gaccatggat attctgggat atcgtatggg
     1741 aagtatgaac gaaacacttg gcgaaaatga taaaacgact gcagatagca gccttaaggg
     1801 taaaaacgaa tgacagtaaa agagagaata gcagcacttc gtgcacgcat gaaagaaaca
     1861 ggaattgatg catatctgat tcctacagat gattttcatg gttcagaata tgtaggtgaa
     1921 tatttcaaat gcagaaaata tatcacagga tttaccggtt ctgcaggcac tgcggtgatc
     1981 atgcaggata tggcaggatt atggacggat ggacgttatt ttatccaggc tgcagatcag
     2041 ctggagggaa caggaattac tttatttaaa atgggtgaac cggaagttcc cacagttcat
     2101 gaatttctga aaaaaaatct gacacaggga aggtgtctgg gatttgacgg acgtactgtc
     2161 agtgcaaaag aggcagcaga attggagaaa atgctggatg aaaacggtgt gtctctcagt
     2221 gttgatcacg atctggcagg cgatatatgg gaaaaccgtc cggtactttc ctgtgaaccg
     2281 gttacagagc tggatataaa atgggcagga gaatccagag ctgataaatg cgcaagaatc
     2341 cgcaaagcaa tggagaagaa gggtgcagat ttatttgtac tgacttctct ggatgatatt
     2401 gcctggctgt taaatatacg tgggggagat atccactgtt gtccggtggt tctttcttat
     2461 cttgtaatga caaaaacaga gatcagactt tttgcaaatg agaaagcctt tcagacagac
     2521 gtactggaag cgctggaaaa agatggtgtg accctttttc cctatgacgg tatctatgag
     2581 tatgtgaaaa catttaaaaa ggacaaaaaa gttcttctct gcaaaaagaa agtcaacagt
     2641 cgtctggtta gcaatattcc ggcagacacc cggattctgg atgaagaaaa tcttacactt
     2701 cttcccaagg caacgaagaa tcctgttgag gtggaaaatg aacgcattgc gcatatcaga
     2761 gacggagttg cagttacaaa gttcatatac tggttaaaga agaatgttgg aaggattccg
     2821 atcacagaat taagtgcagc agaaaagctg tatgaattcc gttcggaaca ggaggatttc
     2881 atagataaca gttttgatcc gattattgcc tatggaaagc atgctgctat tgtacattat
     2941 tttgcaacac ccgaaacgga tattcctctg gaaccatccg gctttcttct ggcagataca
     3001 ggaggacatt ataaagaggg aactactgat attacccgta ctgttgtcat gggaccgact
     3061 actgaggaag agaaaaagta cttcacagca gttttgcggg gaactctgaa tctgggagct
     3121 gccagatttc ttcatggctg taccggtgta aatctggata ttctggcgag acagccgcta
     3181 tgggaaatgg gagagaattt taaacatgga accggtcatg gagtaggata tcttctgaat
     3241 gtccatgaag gacccaatag cttccgatgg aaaattgttc cgggtggaaa tgcagtgctg
     3301 gaggagggaa tgatcacctc tgatgagccg ggatattaca gagaggatgg atttggaatc
     3361 cgtcatgaaa atctgatggt ctgcaaaaaa gctgaaaaaa cagagtatgg tcagtttatg
     3421 tgttttgaat ttctaactat ggtacctttt gatctggatg gagtggtgcc ggaactgatg
     3481 agtgcccggg aacgtaacct tctcaatgat taccatgcac aggtatatga gaagatttct
     3541 ccgtatttga acgaagaaga aaaagaatgg ctgaaagatg ctacccgagc aatctgataa
     3601 aaataaaaaa atattttaca aaatcaaaaa gaggaacagc cgtgatggac agctgttcct
     3661 ttttgattta ttatctggct tgttttattc agaaactttt gcaaactggc tgttatataa
     3721 agtatggtaa aatccacctt ttgcaatcag ctcatcatga gtaccctgct caatgatact
     3781 tccgtctttc ataacaagaa tcagatctgc atttcggatg gttgaaagcc tgtgagctac
     3841 gataaagctt gttcttccct ccatcattcg ttcaaacgct tcctgaattt gtaattctgt
     3901 tcgtgtatca atactggaag tggcttcatc caggatcagc atcggaggca gacagagcat
     3961 aactcgtgtg atacacagca gctgtttctg tccctggctt aagctgtctt cgttgagcat
     4021 ggtgtccagt cctttaggaa gcctccggat aaattcccag ctgtgggtaa gcttggctgc
     4081 ttcgatgatt tcagtatctg tagcttccgg ttttccaatc gagatattgt cgcggacagt
     4141 tccgtttttg atccatgttt cctgaagcac cataccatag ctgcttctga gagaatggcg
     4201 ggtaatgtct ctgatcggtt tgccgtcaac ggaaatagat ccgaaattta catcatagaa
     4261 tctcatcaga aggttgataa aggttgactt accgcatccg gtaggtccta caatggcaac
     4321 gcgcatacct ggttttacat ggagattaaa gtcctcaatc agtttctttg attcatcata
     4381 atggaagcac acattcttaa tatctacttc accctttaca tctttcagtg tctcagaagc
     4441 ctctgcaact tccggttcct cctccagcag atcgaagatt ctgcctgcac aggcaagagc
     4501 attctgaagt tctgtaacaa cggaactgat atcattgaat ggtttcatat actggttggc
     4561 ataggagaga agtacggaaa gtcctccgac tgtcagtctg cctccaggga taatgaatgt
     4621 acccaccagt gcaacacagg cataaataac attattgaca aaacgggtgg aagggtttgt
     4681 caggctgctg taaaaaacag ccttcagact gcattcctgt aattcttcgt taacctttgc
     4741 aaagcgttca gaagattttt cctcatatcc aaaagcctga acaaccttct ggtttccaat
     4801 catctcttcg atgagagcag tctgacgtcc tctggcatcg ctttgcttcc ggaacatctg
     4861 gaaggtatgg gaagaaataa atttggccac caaaaagctt acgggggtca ggacaatgac
     4921 catcaatgta atccagaaat ttttggagaa catgaagatc agtgttccga tgatcgttac
     4981 gattccggaa aaaagctggg taaatccaag cagcatacca tcggatagaa tatctgtatc
     5041 tgcgataata cggctgatga tatctccggt actgtgtccg tcaaggtaag agaggggaag
     5101 tacctgaatg tgtcggatgg ctttggcacg gatatccttt actgtctggt aggtcatgcg
     5161 gttattgatc acattcataa gccacgtggc agcagaagag aggatgacca ttacaaggat
     5221 acgtgacagg taataccaca tcatttcgaa gtttacctga tgttgggcaa tgacctgatc
     5281 aatggcattt ccgaatagga ttgggacata cagctgaagg ataacggaaa ctgctgccag
     5341 tatgatactg aggatcagca gaaaacggta tcttccgatg aaacgcagta ctttaagaaa
     5401 agtttcgctg cttttgcttt tagcaggatc ttttattgtt aatctgctca tacagtcacc
     5461 tccttcatta tattacctgc agatacagag gagtatctgg ctctttcttc cggaaactga
     5521 gagaagtaga tttcccggta agtatcacag gtacgtagca gttcagcatg agtaccctta
     5581 cctgccagag taccgttatc aaggacaagg atcaggtctg cctgctgaat gctggaggaa
     5641 cgctgggata ccagaaatgt agttactttc cagtcaagtc tgttgagaga cttacgcagt
     5701 gctgcatcag tggcaaagtc cagggcactg gcactgtcat ccaggatcag gatttcaggt
     5761 ttttttacca gggcacgggc aatggtaagt ctttgtttct ggccgccgga aaggttttta
     5821 ccgttctgtt ccagcataaa atcaagctgt cccggtttac cctctactac ctcttttccc
     5881 tgtgctgtgg taagtgcctg ccacagatcc tcgtcagagg catcttcccg gccccatttc
     5941 agattgtccc ggatagagcc tttgaaaaga gctgccttct gtggaacaac gccgattctg
     6001 gagcggagat cacttctggt gtaattttca atattctgac catccagcag aacagttcct
     6061 ttgctggcat catagaatct ggaaatcaga tttaccagag tggtctttcc gcttcctgta
     6121 ccaccgataa tacctacggt ctgtcccttt tttacagaaa aactgatatg ggaaagactg
     6181 ggggcaccgg ctttgctgta ctcaaaggtt acgtcattga atacgatggc attttcagaa
     6241 agtgatgcat cagcagttgc tgttgcaagg tccttcgata tctgagcaga atatgtggag
     6301 gaagaggggt aatccatagt agatttcact ttcaggatat ctgccacacg tcctgcgcag
     6361 gctgcagatt tgttcagggt gatgatcagg gaggcaagct tgatcagttc cacgatcatc
     6421 tgagccatat agttataaag ggcaacaacc tgtccctgct gcataccgcc aagatttact
     6481 tctactcctg ctttctggat cagaataaca gtagcaatat tgatcagtac gtaagtgacc
     6541 ggatttaaca aagcggaaag ctttcctaca aagagattta actttgtcag ctcctgattg
     6601 cgggtatcaa attctgcaac tgcctctttt tcgcggcaga atgcacggat aacgcggacg
     6661 cctgtaaggt tttctctggt cagtccggtt actgtgtcca gttttccctg tactttttta
     6721 aacagaggaa tactgagaaa cataatgaca aagacaacca gaaacagaaa cgggatcgca
     6781 acagcaaaaa ccagggcaca tttaaagtca atggtaaatg ccatgaccat ggacccaagt
     6841 acgataaacg gacttcgaag aagaagacga agtcccatat ttaatccgtt ctgaatctga
     6901 ttgacatcat cggtgagtct tgtgataaga gtatctgttc ccagtgtatc caactctgta
     6961 taggacagat gctgtacatg gtcataaact gcctgtctta attctgtggc aaagcccacg
     7021 ctggctttag cggcaaagaa ctgagctgtg atggtactgg caagaccaag agccgccatt
     7081 agtataagaa tagaaaatct ctggacaatg tatccgttgt cgtggtttgc aatacctaca
     7141 tctatgatct gtgcaatgac gataggtacg atcaggtcaa atacaacctc cagaaattta
     7201 aaaaatggcg caaggatgct ttcttttttg tagtttttta aataaaccgt caatgaacgc
     7261 attttaaaaa ttccttcctt tcgtaaaaat ctttcctata ttattccttc ctttttttga
     7321 aaaataatac attcaaaagt gtatcattta agactttttt gtcaagaaga atgtgcaaaa
     7381 acagatgaac tttggagaaa attcagcttg acttcaaaaa aagatattac taaaatattc
     7441 cgtagcgcta tttgtacgct ggcaactgat aaattattat taccataatg aggaagagac
     7501 agactatgga gattattgag acatttggtc attatgtgga aaatctgacg gataaaaagc
     7561 ctcagtcagc ccgacggctg ttaaaaaccg gctgggaggc gcagaatctg aagttccgtt
     7621 acatgcagga caagagactg atgcctgcag acaggcatct tgcaaatctg atgatggata
     7681 ccatgctgcg gccccttcag aaaccggaag attctgttat tgtaagtatt tttacaccct
     7741 gcgaaatgat gcaggaggtg ggattacatc cctataatgt agagggattt tcctgctatc
     7801 tttctgcaag caaagcagag aggacgtttc tgcagcaggc agagaatcag ggaattgcag
     7861 agacactgtg cagttatcac aagacatttc ttggtgcagc gcagaaagga cttctgccaa
     7921 agcctaaatg tattgtttat accaacctga cctgcgatgc taacctgctc actttccgta
     7981 ccctggcaga tttttaccag gtacctgtat ttgccattga tgtaccatgg aatcagacca
     8041 cagagaatgt acagtatgtg gcagatcagt taaaggattt aaaaatattt ctggaaaaaa
     8101 atacaggaaa aacaatctct gaggacagat taaaggaacg tcttgcctgc agtaagcgga
     8161 ctctggagaa ttacaaaaaa tatcagcaga tgcgtgcaga cagatatgtg ccctctgatc
     8221 tggtcacacc cttgtatgca ggaatgacaa acaatatcct tctgggaaca gcagaagaag
     8281 agaagtatac acagatgctt cttgaagata ttaagaaagc accggcagcg aaagggaaac
     8341 acatttactg gatgcatacc attccattct ggtcggatgc agtgcgccag gagctttgct
     8401 tcagtgagaa agcccagatc gtaggatgtg aacttgcaga aacctgtgag ccggattttg
     8461 atcctgagaa cccctttgaa gcaatggcag aaagaatggt atatcattca ctgaacggaa
     8521 gtgcccttag aaggattgaa gccggtatcc gccatgcgaa acaggcagga gcagacggtg
     8581 ctgtgtggtt tggacattgg ggatgtaaac atacgcttgg tgcggcacag cttgcaaaga
     8641 agaagttcga ggaagccggt ctgccccttt taatcctgga cggtgacggg tgtgatcgaa
     8701 gccatggagg agaaggacag acttccacca ggctgggagc ttttctggaa atgctgggag
     8761 gtgctgagaa tgaataaaac ttactatgtc tgtaaatata ccccaattga acttctggaa
     8821 tctcttggcg gggaatgtga gaactttaat catatgccgg agggatttga cctggccgat
     8881 caggtttcac atcccaatat ctgcggtttt ggaaaaacac ttctggaagg agtcatggag
     8941 gggaaaatca aggaacttgt cctggtgagc tgctgtgata ctatccggag tgtctatgac
     9001 attctgcttg aaagcggcaa gctggatttt ctctatattt tggatgtgct tcactgtgac
     9061 agtgcctgta gcagagagcg tatggctgta cagttaaaag ggctggcgaa ggcttatgca
     9121 cagtacaaag gcacagagtt tgatgccgga aaattccggg ctgctttcca tgcacaggag
     9181 aaaatcacaa agtcccatat tgcagtgctt ggcgccagaa tggggcagga attatttgaa
     9241 atgaccagca aggctatgcc tcttcctgta gagaatgata cctgcgtgca taaccgttct
     9301 gtgggaaata tacttccacc ggagggtgct tcttttgatg agctgatgga ctggtatgca
     9361 ggtgagattc tggggcagat tccatgtatg cgtatgatgg acccgacagg tcgtaagaag
     9421 ctttataatg atccgtctgt tgcggggatt atttatcata cagtgaagtt ttgtgatttt
     9481 tacagcttcg aatatgctga gatcaagaac catacagatg tacctctttt aaaaattgaa
     9541 tcagattata ctattcagag cagcggtcag cttcttacca gactggaagc ttttgcagag
     9601 agcattcagc ctgaaacact ggagcagacc atagatggag acacaaaagg agagagaaaa
     9661 atgggaaaag gttatttcgc agggattgac agtggttcca ccagtacaga tgtggtgatt
     9721 ttaaataaag atcatgagat tgtgaccagc attatcctgc ctacaggagc aggagctgct
     9781 atcggagcag accgtgccct tgcagaagca ttgaaggagg ccggattgca gagagaagat
     9841 attgatgcgc tggttactac cggatacgga cgtacagcta ttaaaaatgg tgataagagt
     9901 atcacagaga tcacctgtca tgcaaggggt gcgcatttcc tgaatccgga agtccgtact
     9961 gttattgata ttggcggaca ggacagcaag gtgatccgac tggatgagaa cggtgcagtt
    10021 gcaaactttg ttatgaatga caaatgtgcg gcaggaaccg gacgatttct ggaaatgatg
    10081 gcacgtacca tggaaatgaa tctagatcag atgagcgaat gtgggctgga attcaaagaa
    10141 gatattacaa tttccagtat gtgtacagta tttgcagaat cagaagttgt atcactgatc
    10201 gcccagaata aggcaacaga tgatattgtc catggcctga ataaggcggt tgccgtaaag
    10261 actgccgccc ttaccagacg tgtgggcggt gaggagaaat atatgatgac cggtggtgtt
    10321 tctaagaata agggtctggt aaagacactg gaagagaagc ttggaacaaa gctggtgatc
    10381 agtgacaagg ctcagctttg cggtgcactt ggcgcagcac tgtttgcggc tgatatggct
    10441 gatgtgtaaa tttttagtta ctgttcacta ccaatgtcat taacttaagc tatttggcaa
    10501 cattgctttg atgaaaaata ttaataaaaa gatttggatg tgataaaaaa gcgtaggatg
    10561 cgaacaagat aggatgtctt attgaatttt aggtacaaca aaaaggcaaa atcaatattt
    10621 aacattgaaa tttgcctgaa aatgaaatat agttaatgta tgagctaaat gttaatgtct
    10681 ataacaaaaa ctcatcggaa gtttaaacct atgctggcgg gcaaaggttc ttccaggtct
    10741 gatcggctca atattttgag cgatcagact ttctacattt atctttgttg tcccatcatg
    10801 aatccttaag aaatccctgc atgttttgag tgcggatgaa taattcgcct gatattcata
    10861 ggcacagtct tcacgcttga tcgttacatt tatgattatg ctggaactga agttatataa
    10921 aataactctg gcccatactt cctgtacaat ataagcatat ttttttgaat gaaatgcttt
    10981 cagacacagg gaatatttca gatcccggaa agaattttcc tcagaccatc tcaaatgata
    11041 aagcatttcg aaatcttctg ttttaaattc atcccttgga agattagtgg caatattttc
    11101 ataagaacca tccttaagc
//
