LOCUS       gnlProkkaDPOLIJOH_20   18961 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DPOLIJOH_20.
ACCESSION   gnlProkkaDPOLIJOH_20
VERSION     gnlProkkaDPOLIJOH_20
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:18:57
            Original ID  :: gnl|Prokka|DPOLIJOH_20
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18961
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18961
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7587:8961]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7588..8961
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..18961
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..18961
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             2..235
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MCHRLLRGDGAEDQGAEEIHKKDFRDTELQSLLKGFQRPAAAPAV
                     DGGQGVAGQGYHILYRDRIRVFAQQLFIVDVH"
     CDS             complement(216..515)
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MHKLICCYKEKACDKCVIHADRKFCFIETTQTVFDNLLRCQLQHL
                     FRLAVAVYRFTCFCRAILPIPKLSDKLFALRDFVNLFVYIIVNTAYNDANERLL"
     CDS             554..997
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MALSTRELLARLLKCEAGGEGENGMRAVASVIVNRTRVPNGEFAR
                     VSKGGDFRAIMEQPNQFTCLKTTVGGQYNPQNVYNIRPDEIHYNIADWALAGNTDSSVG
                     NSIFYFNPFSDTCPTFFPSNNGVIYNRVGDHCFYSPTEAYSKT"
     CDS             1012..1719
                     /locus_tag="ctg20_4"
                     /transl_table=11
                     /translation="MDNSSNMTVNTTQITNQINPEHHYGLDKNKACLNNSCPSNTADIG
                     CYIPAIDEIMRHNQGAPSVAHPNMTEKVQKSNDNPSLEQAEIAYEEGGSTSEEQPENIN
                     KYSGNLQNIPFIKNLKKIDTSIPVLPATPATTASSGATVATPIRQNIGMSMSDYQYPFP
                     VTAESLRYHNGFMRTQIGRRITVDFLMGANTIVQKTGYLLGVAQDYILINEIDTNDITT
                     CDYYNIKFIRYYY"
     CDS             1971..2870
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MKFCKYCGAQLEDNAVCNCEKSRAAQAQPQQANAQAQPQYQQPVQ
                     PQQPQYQNPVQQQYAQPQNPQTQQSPYAVNNTAPIGENAFVKALKNIPVVFTSFFKDSK
                     TVIKTAKAEKDIILGVLFSAIFFIALILGNMFLMLSMSALDFPKTLLVSLVTAVLIGGF
                     YSVILFAYVKKYKTEENTAKAFIDSFITFSIESIPASIGWILAGLCALISVYMFLFFFV
                     IVMLYLVISLVNQVKANVPEAKNSALFTLILTLIVAVAFMIVFFIGAKLTMWSFNTSTF
                     TTSVLTSLIGGGSYPSWY"
     CDS             complement(2930..4030)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_6"
                     /sec_met_domain="PF04055 (E-value: 7.1e-21, bitscore: 65.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNSIGLYIHIPFCKHKCPYCDFFSGNADENAFDNYVIELKDKIK
                     YWSEKAKRDVATVYFGGGTPSVLGADRLCDILDFIKFNFNIQNNAEITVEVNPDSAKTI
                     DFKKMYACGFNRISMGMQTAVEDELRLLGRIHSIDDAKTSVERAKSAGFNNISLDLMMG
                     IPNQTIESLEKSISFCADCKVTHISSYILKIEENTPFYKVQNKLKLADDDMQAEMYLKA
                     VEMLDSLGYKQYEISNFAKHGYESRHNTNYWRCGEYIGIGPSAHSFFEGKRFFYSRSMD
                     DFNNNKLSFEGTGGDEEEFIMLSLRLKSGLNYSEFEEKFGYTLPPYIIKKAKEYEKYGY
                     TNVTDKSISFTPKGFLVSNSIISELI"
     CDS             4279..5865
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 109.2; E-value:
                     4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MSSFKEEISKRRTFAIISHPDAGKTTLTEKLLLYGGAINLAGSVK
                     GKRTAKHAVSDWMEIEKQRGISVTSSVLQFKYNGYCINILDTPGHEDFSEDTYRTLMAA
                     DSAVMVIDGSKGVEKQTIKLFKVCVMRNIPIITFINKMDRDAKNSFDLLEDIENVLGIH
                     TYPVNWPIGSGKEFKGVYDRNSKKILAFTANNGQKEVEKKELTLDDPALEDTIGYYHKQ
                     DLFDEIELLDGAGDEFDLEAVRNGQLTPVFFGSALTNFGVEPFLEQFLQLTTPPLPRET
                     VDEKVEPMSDFFSAFVFKIQANMNKAHRDRVAFMRICSGKFEKNMEVFHVQGNKKMRLS
                     QPQQIMAQEREIVDEAYAGDIIGVFDPGIFSIGDTICSPGHKVQFRGIPTFAPEHFALV
                     RQKDTMKRKQFIKGTSQIAQEGAIQIFQELDAGMEEVIVGVVGVLQFDVLKYRLQNEYN
                     CDIIMETLPYEFIRWIVNDDIDPKTLDLASDTKKIQDLKGNHLLLFTSYWSINWALEHN
                     KGLELAEFGTN"
     CDS             5889..7292
                     /NRPS_PKS="Domain: Aminotran_5 (52-217). E-value: 1.3e-13.
                     Score: 42.5. Matches aSDomain:
                     nrpspksdomains_ctg20_8_Aminotran_5.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_8"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.3e-09,
                     bitscore: 28.3, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.5e-12, bitscore:
                     37.8, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 8.7e-14, bitscore:
                     41.7, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLYDKLKNYSKSGIYPFHMPGHKRTDITEEGIIPYNIDITEIHDF
                     DNLHSPNEVIDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKILMARNCHK
                     SVYNSAELFNLNVDYIFPDTDSRYNILTSVSPCDIEDKLTKHNDEIRLVIITSPTYEGV
                     VSDIKSISEICHKHGAKLLVDEAHGAHFPFSDSFPDEALNCGADAAVLSLHKTLPSLTQ
                     TALLITNDSELSEILAENLAVFETSSPSYILMSSIEKCLDFCENSKDKFKEYCCNLKTV
                     REKLKNLKYLKIYDKSDTDFDYDIGKIVISTANANISGTKLAEILRNNYQIETEMAYSD
                     YVIAMTSVCDTEKAFDMLSDALISIDSELSKGADTERVPLKNLYTGKNFNACELYKFNK
                     ETIPFQNSEFRTSAEYIWAYPPGIPLIIPGEIISKELINYIEYLSACKVEIMSTKGGMT
                     DNISVVKKD"
     aSDomain        6045..6539
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg20_8_Aminotran_5.1"
                     /evalue="1.30E-13"
                     /label="ctg20_8_Aminotran_5.1"
                     /locus_tag="ctg20_8"
                     /protein_end="217"
                     /protein_start="52"
                     /score="42.5"
                     /tool="antismash"
                     /translation="EVIDEIQKKAAKLYNAKNAFILINGSTGGILSAIRSMTNQGDKIL
                     MARNCHKSVYNSAELFNLNVDYIFPDTDSRYNILTSVSPCDIEDKLTKHNDEIRLVIIT
                     SPTYEGVVSDIKSISEICHKHGAKLLVDEAHGAHFPFSDSFPDEALNCGADAAVLSLHK
                     TL"
     CDS             7588..8961
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_9"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 3.2e-31,
                     bitscore: 98.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.1e-15, bitscore: 46.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 5.2e-15, bitscore: 46.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.9e-20, bitscore:
                     63.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKLNGYNIVLDVYSGSVHAVDDLAYDVIAMYKNATKEQIID
                     EMLSKYADNPEITKEEISDCIDDVKELEKQGKLFTDDKYENLAFDFKKRNTVIKALCLH
                     IAHTCNLNCEYCFASQGKYHGERALMSFEVGKRAIDFLIENSGSRVNLEVDFFGGEPLM
                     NFDVVKQIVAYARSIEKEHNKNFRFTLTTNGMLVDDDVIEFANKECHNVVLSLDGRKEV
                     HDHLRKTVNGKGSYDIIVPKFQEFVKKRGNKGYYVRGTYTHNNTDFTNDIFHMADLGFT
                     ELSMEPVVCAPDDPYALTYDDLPILFEQYEILAKEMLKREKEGRPLTFYHYMIDLTGGP
                     CIYKRISGCGSGTEYMAVTPWGDLYPCHQFVGDEKYKLGDIFNGVSNTKIQDEFKLCNA
                     YARPDCKDCWARLYCSGGCAANAYHATGSITGIYEYGCELFRKRMECAIMMKVAEAEG"
     CDS             9027..9836
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MNEKIIMLGTGSAMVTDCYNTCFLLKSENDCLLVDAGGGNGILSA
                     IKKSGVAWNSIKTMFITHSHTDHILGAVWVIRQISALMNSGKYDGNFNIYCHDECVDSI
                     TAICNHTLAPKFLKNINTKIFINEVKDGEMQNAGSIRLTFFDIFSDKTKQFGFKAVFPS
                     GKVLACLGDEPFNEKCRNFVQNCDYLMCEAFCLYSQKDIFKPYEKFHSTALDAGKLAES
                     LFAKNLILYHTEDETLQTRKKTYTSEARTVFNGNIFVPDDFEVIDLK"
     CDS             complement(9828..11741)
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MFSTDKSSFNKKDVSDWDYKISLAGNPNVGKSTIFNELTGLRQHT
                     GNWTGKTVEFARGCCKIKDARFCITDLPGCYSLLSFSGEEAVTRECLIQNQNDCVVIVV
                     DCGVIERNLSFALQVLSVTKNAVLCLNLCDEAEKNGIKIDCDELSLNLGIPVVKTCATD
                     KKGLDELKKAIYNVCSGKIKCFRVERNFEGVDILSEKNYKQNIEKLSQIGNKISSDCVK
                     YEKSELNACTRKLDKILTSKTTGIPIMLAMLGILFWITVVGANYPSEWLSNLFGFIKEK
                     LYILFDFLHAPDVVTGLLIDGVYTTLSWVVSVMLPPMAIFFPLFSLVEDSGYLPRIAFN
                     LDRYFSKCGAHGKQSLAMAMGLGCNACGVTGCRIIESPKERLIAILTNNFMPCNGRFPT
                     IIALLLMFFAGTAFTLSSSLEVAALLIGIIVFCVFITLVISKVLSVTILKGEQSGFVLE
                     LPPYRKPQILKTIVRSLLDRTLFVLGRAVAVAAPAGAIIWILANVHISDVSLLKYCTDF
                     LDPFGRFIGVDGVIIMAFILGFPANETVIPIIIMSYMASGTLVDYSSYDQLFQLLSMNG
                     WTITTAVCTIILCILHYPCSTTCLTIKKETGSLKWTLVSMALPTAMGIVLCIITAGVMR
                     LF"
     CDS             complement(11757..11993)
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MKEKCSLDKLPLGVTGIVYRVNCNENIKNRIFDFGIMENSPVIPL
                     FTSPFGDPSAYLVKNAVVALRNNDCKDIIVTPE"
     CDS             12462..14351
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MNKSFKKILSIVLSVMMISSLMTVSLSVSAVEDGKVRVIVRNDTY
                     SVENGAPWDGVLVDEWVSINNDTTMMSAVADALNNHGYTQEGAENNYISSINGLAAFDG
                     GTMSGWMGTLNDWFTNSGYASYTVADGTLESGDEIAIMYTSNGYGEDIGGTWANNDTTV
                     KSVEITGAELSGEFDPSVTDYTLTIDTPSADVNVVPTATNKNFQTRKYKNEYLPSDDSA
                     FYKRSQTVSVSDGDKIIIGCGDTAWPSMNTSEGGTVYTFTVKYAPSAADTVSNKIDEVA
                     KHLASQDAPTVSSVGGEWTVLGLARAGKITDEIADSYYQNAVKYVEEKGSAKLHNTKST
                     DNSRVILALTAIGKDVTDVASYNLLEPLADMDYVKKQGINGPVFALIALDTGDYEIPQT
                     DAANPTTREKLVQTILDAQVANGGWTFFGSTADPDMTGMAIQALAPYYTTNSDVKEAID
                     KALTAMSNAQNENGGFASWGSVNSESCAQVLVALTSLGIDPTNDERFIKNGNTLIDAMM
                     SFSAENGFGHTDTTYNQMATEQGFYAFVSFDRLVNGKTSLYNMTDRLAENYAVGDVNLD
                     NTVSVIDATLVQKQIVNLEQLSKVSLIKADVNHDGVINVVDATEIQKIIVNLV"
     CDS             14942..15307
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="MDDLDPEKIELVPKDGIILKKQKVQFKEGESVYDVLVKVCKDNNI
                     HMESSWTPMYNSAYIEGINNLYEFDCGSLSGWMYKVNEWFPNYGCSRYVLKNGDDVVWC
                     YTCNLGYDVGGGYATGE"
     CDS             15382..16200
                     /locus_tag="ctg20_15"
                     /transl_table=11
                     /translation="MFIMNPVCLAVSFLCALVTALYLNGKNAVRLSLVFLLPMILLIVL
                     VNPVFNHEGMTILTYFPWDNPLTLESIVYGIASAFLLSSTVLWFSSFNAVITSDKVVFL
                     FGRIMPSLSLVISMALRFVPRFSAQMKLVRNAQHTIGRDIDEGTLFQRIRNAVKILSIM
                     ITWSLENAIETADSMKSRGHGLKGRTSYSLYKFDKRDAFMLCTILFTGLVLMILLFTNA
                     IKFRYYPSIKGDLFTVQSVIFYIFYTFLMLIPLSVNIGEGIKWKHMQSKI"
     CDS             16173..18833
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 164.6; E-value:
                     5e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg20_16"
                     /transl_table=11
                     /translation="METYAIKNLSFRYPETGIDVLKDITFSINEGEFITVCGPSGCGKS
                     TLLRHLKPDLSPHGVLSGEIFFEEKPISDLSHREQSSKIGFVMQSPENQIVTDKVWHEL
                     AFGLESLGYDNNTIRKRVAETASFFGIQNYFEKSVLELSGGQKQILNLASIMAMQPSVL
                     ILDEPTSQLDPIAASEFLHCVSRINHELGTTVIITEHRLDEVLPLSDRVLVIENNGISA
                     FDSPQKVGKILKEKDSKTFLSMPAPMQIWQAVTENDNTDCPVTVPSGKKWLSEYAKSHK
                     MYELTPESIQKHSDKEAVSLNDIWFRYEKSGADVLKGLSLKIYQGEFAAILSGNGMGKS
                     TALSIICSLNKPYRGKVEISPLNKNSFDTLVAVLPQNPQTLFLKKTVLEDLYEVFDGRK
                     ISKEEKERRVTAAVKLCRLESLCNRHPYDLSGGEQQRAALAKILLIRPQILLLDEPTKG
                     LDAEFKIEFAQIIYDLNKAGITVLMVSHDVEFCAVYPSRCLMFFNGEVVSEGTPRTFFS
                     SNSFYSTSASRMSKGIIDNAESSNDVIYACTGKNRDVQINRNTPDIDLFKNDTENIPHQ
                     KNKAENKKLSVFKKIFGFFGAVLFILGLIVNLEYIPNFSAKTLPTWFNWGIIGVSVALL
                     MIAFGTKSKRPIDLPRKSSKLSKRTVSMAIMVLLAIPVTIFVGMTYLQDQKYLFISLLV
                     MIECMIPFFLVFEGRHPKARELIIISVLCAIAVAGRLAFTMLPQFKPVVAIVIISGVAF
                     GGESGFLVGAVSMLVSNLMFGQGPWTPWQMFAAGIIGFIGGILFKKGLLGRTRTSLCIY
                     GFIATMVIYGGLMNLYSALTSHSAFNLNMLITFYVQGFPMDIVHAVSTVIFLFFGAEPM
                     LEKLDRIKVKYGLIE"
ORIGIN
        1 gatatgccac aggcttttgc ggggggatgg agcggaagat cagggagcag aagaaatcca
       61 caagaaagat tttcgggata cagaacttca gtcacttttg aaaggctttc agcgacccgc
      121 ggctgcacca gctgtggacg gtggtcaggg tgtagccggt cagggttacc acatccttta
      181 ccgtgaccgc atccgggtat ttgcgcagca gcttttcata gtagacgttc attagcatca
      241 ttatacgcag tattgacaat aatgtaaaca aaaagattaa caaaatcacg caaagcaaac
      301 aatttatccg atagttttgg gattggcaaa atagccctgc aaaaacaagt aaagcggtag
      361 acagcaacag ctaatctgaa taaatgttgt agttggcatc tcaaaagatt atcgaacacc
      421 gtctgagttg tttctataaa acagaatttt ctgtctgcgt gaataacaca tttatcacaa
      481 gctttttctt tgtaacaaca aattaattta tgcataaaat atcattgaat aaaataacgg
      541 ttggtgaaaa aaggtggcat tgagtacaag agaattgctt gcaaggcttt taaaatgtga
      601 ggcaggtggg gaaggtgaaa acggaatgcg tgccgttgcg tcggtaattg taaaccgaac
      661 ccgtgttcca aacggggaat ttgcaagagt cagcaagggc ggagatttcc gtgccataat
      721 ggaacaacca aatcaattta cctgtcttaa aacaactgtc ggaggacaat ataatcctca
      781 gaatgtttat aatatacgcc ctgacgaaat tcactataac attgccgatt gggcattggc
      841 gggcaatacc gattcatctg tcggaaattc aattttctat tttaatccat tttcagatac
      901 ctgcccaaca ttttttccgt caaacaacgg agtaatttac aacagggtag gggatcattg
      961 cttttattcg cctaccgagg cttattccaa aacataaagg agcataactt aatggataat
     1021 tcttcaaata tgacagttaa cacaactcag ataacaaatc agattaatcc cgaacatcat
     1081 tacggacttg acaaaaacaa agcctgcctc aacaattcat gtccgtcaaa cacagcggat
     1141 atcggatgtt atattcctgc gattgacgaa attatgcgac acaatcaggg cgcaccgtct
     1201 gttgcacacc caaatatgac agaaaaagtt caaaaatcaa atgacaatcc ctcgcttgaa
     1261 caggcagaaa tagcatatga agagggcgga agtacatcag aagaacaacc tgaaaatata
     1321 aataaataca gcggaaatct tcaaaatata ccgttcatta agaacttaaa aaaaatagat
     1381 acatctatac ctgttttgcc tgcaacccct gctacaacgg cgagttccgg agccaccgtt
     1441 gcaacgccga taaggcagaa tattggaatg tcgatgagtg attatcaata tccgtttcct
     1501 gtaacagccg aaagtctgag atatcacaac ggttttatgc gaacacaaat cggaagacga
     1561 atcaccgttg attttctcat gggagcaaac acaattgttc agaaaacagg ctatctttta
     1621 ggtgttgctc aggattatat ccttataaat gagattgaca ccaacgacat cacaacctgt
     1681 gattactaca atataaaatt tataaggtat tattactaaa ccacagcggc aaaagctata
     1741 aacattagtt tttgccgctg ttttattgtc attatttgct atgtgtatat catttcatta
     1801 ttttaacata taattttctg tagtgtaaaa aattaaaaaa ttgtaagaaa tattgaatta
     1861 ttgctgtaat ttgtgatata ctgtgagcgt tgatgttatc acttctcaat aaacaaacaa
     1921 caggtagcta taagacctgt tacatattat tttatcttgg aggaatcacc atgaaattct
     1981 gtaaatattg cggagcacag cttgaagaca atgctgtttg caactgcgaa aagtcaagag
     2041 ccgctcaagc acagcctcag caggcaaatg cacaggcaca gcctcagtat cagcagcctg
     2101 ttcaaccaca acagccacag tatcagaacc ctgttcagca acagtatgca cagccgcaaa
     2161 accctcagac acagcagtcg ccctatgccg taaacaacac agcacccatt ggggaaaatg
     2221 cttttgttaa ggctttaaag aacattcctg ttgtgttcac ttcattcttt aaggattcca
     2281 aaactgttat caaaacagca aaggctgaaa aagacatcat tctcggcgtt cttttctcgg
     2341 caattttctt tattgcactc attcttggca atatgtttct tatgctttct atgagcgcac
     2401 ttgattttcc gaaaacactt cttgtaagtc ttgttactgc tgtccttatc ggcggcttct
     2461 attctgttat tctctttgca tatgtaaaga aatacaaaac tgaagaaaac acagccaaag
     2521 catttattga ttcattcatt acattttcaa ttgaatctat tccggcatca atcggttgga
     2581 ttttggcagg tctttgcgca ttaatcagcg tatatatgtt cctgttcttt ttcgtaatcg
     2641 ttatgcttta ccttgttatt tcacttgtaa atcaggtaaa agctaatgtt cccgaagcaa
     2701 agaactctgc attattcact ttaattctca cactcatcgt tgccgttgca tttatgattg
     2761 tattcttcat cggcgcaaaa cttactatgt ggtcatttaa cacaagtaca tttacaacaa
     2821 gtgttcttac atcgcttatc ggcggcggtt catacccttc atggtattaa tctgacatac
     2881 aaattcataa cataaaatta acgctccgaa tttattctcg gagcgttttt tatatcagtt
     2941 cactgattat tgaatttgaa acaagaaaac ctttcggtgt aaagctgatt gacttgtccg
     3001 taacatttgt atagccgtat ttttcatact ctttagcttt tttgataatg taggggggga
     3061 gggtgtatcc gaatttttcc tcaaattcag aataattaag accgcttttt aacctgagag
     3121 agagcataat aaattcttcc tcatctccgc ccgtaccttc aaaagacagc ttattgttat
     3181 taaaatcgtc catgcttctc gaataaaaga accttttgcc ctcaaaaaat gagtgtgcag
     3241 acggacctat gccgatatat tcaccgcatc tccagtaatt ggtattatgt cggctttcat
     3301 aaccatgttt tgcaaaatta gaaatttcat attgcttgta tccgagagaa tcaagcattt
     3361 caacagcttt cagatacatt tcagcctgca tatcatcatc ggcaagctta agtttatttt
     3421 gcaccttata aaacggagta ttctcctcaa ttttcaaaat gtatgatgaa atatgagtaa
     3481 ctttgcaatc ggcacagaaa ctgattgatt tttcaaggct ttcaattgtc tgattaggaa
     3541 ttcccatcat caaatcaagt gaaatattat taaatcccgc acttttagcc ctttcaacag
     3601 aagtctttgc gtcatcaatg ctgtgaattc tcccaagcag ccttaattca tcttcaacag
     3661 cagtctgcat acccattgaa attcgattaa atccgcaggc atacattttt ttaaaatcaa
     3721 tagttttggc ggagtcggga ttgacttcaa ctgtaatctc ggcattattt tgaatattaa
     3781 aattgaactt gataaaatca agaatatcac aaagtctgtc tgcacccaaa acactcggcg
     3841 taccgccgcc gaaatatacg gttgcaacat ctcttttggc tttttcagac cagtatttta
     3901 ttttatcttt taattcaatc acataattat cgaaagcgtt ttcgtctgca ttgccgctga
     3961 aaaaatcgca atacggacat ttgtgcttac aaaacggtat gtgaatgtaa agaccgatag
     4021 aattactcat aaaaacctca taaatgattt tgaggcagaa acacaagttt ctgcctcgat
     4081 ttggaaggta tatgaaaaaa taggaaaaat cacattaagt ccttctgtac caatatatta
     4141 caatatattt acaaatttgt caagtttttg tagcaattat ttttctcaca ttttcttcat
     4201 tctttattga catataccat ccaaaaatag taaaatatag aattgtggat atacttaacc
     4261 tccgaaggga agaaagatat gagttcattt aaagaagaaa tcagcaagcg cagaaccttt
     4321 gcgattattt cgcatcctga cgcgggtaaa acaacactta cggaaaagct cttgctctac
     4381 ggcggagcaa ttaaccttgc aggttcggta aaaggcaaaa gaaccgcaaa gcatgctgtg
     4441 tccgactgga tggaaattga aaaacagcgt ggtatttctg ttacatcatc ggttttgcag
     4501 tttaaatata acggttattg cataaatatt cttgacacac cgggacatga ggatttctcg
     4561 gaagatacct accgtacact tatggcggca gactctgccg taatggtaat tgacggttca
     4621 aagggtgttg agaaacagac tatcaaactt ttcaaggtct gtgtaatgcg taatattcct
     4681 atcattacat tcatcaacaa gatggacaga gatgccaaaa attcttttga ccttcttgaa
     4741 gacattgaaa atgttctcgg aattcacacc tatcccgtaa actggccaat cggttcaggt
     4801 aaggaattca agggtgtgta tgacagaaat tccaagaaaa tccttgcttt caccgctaat
     4861 aacggtcaga aagaagttga aaagaaagaa cttacgcttg acgatcctgc ccttgaagat
     4921 acaataggct actatcataa gcaggatttg tttgatgaaa tagaacttct tgacggtgca
     4981 ggcgatgaat ttgaccttga agcagtccgc aacggtcagc ttactcctgt attcttcggt
     5041 tcggctctta caaactttgg tgttgaacca ttccttgaac agttcttaca gctcacaact
     5101 ccacctctgc caagagaaac agttgatgaa aaggttgagc ctatgtcaga ctttttctct
     5161 gcatttgtct tcaaaattca ggcaaacatg aataaggctc accgtgacag agttgcattt
     5221 atgcgcatct gcagtggcaa gtttgaaaag aatatggaag tgttccatgt tcagggcaac
     5281 aaaaaaatgc gtctttcaca gccacagcag attatggctc aggaaagaga aattgttgac
     5341 gaggcatatg cgggcgacat catcggtgtg tttgatccgg gcattttctc aatcggtgac
     5401 acaatctgtt caccgggaca caaggtacag ttcaggggaa ttcctacatt tgctcccgaa
     5461 cactttgcac ttgtccgtca gaaagacaca atgaagcgca aacagttcat caagggtaca
     5521 agtcagattg cacaggaagg tgcaattcag attttccagg agcttgacgc aggtatggag
     5581 gaagttatcg ttggcgttgt aggcgtactt cagtttgatg ttcttaaata cagacttcaa
     5641 aacgagtaca actgtgatat cattatggaa acactcccat atgaatttat ccgttggatt
     5701 gtaaacgatg acattgatcc gaaaactctc gaccttgcgt ccgatactaa gaaaattcag
     5761 gatcttaaag gcaatcatct tttgctcttt acaagctact ggagcataaa ctgggcgctt
     5821 gaacacaaca agggacttga actcgctgag ttcggtacaa actaaatatt taaaatatcg
     5881 gaggatatat gctgtacgac aagcttaaaa attattcaaa aagcggcata tatccttttc
     5941 atatgcccgg acacaaaaga acggacatta cagaagaggg tataataccg tataatatcg
     6001 acataaccga aattcatgat tttgacaatc tccattcgcc aaacgaagtt attgatgaaa
     6061 ttcagaaaaa ggctgcaaaa ctttacaatg caaaaaatgc tttcattctg attaacggtt
     6121 caacaggcgg aatactttct gcaatccgat caatgacaaa tcaaggcgac aaaatcttaa
     6181 tggctcgtaa ctgccacaaa tctgtatata attcagcaga actgtttaat ctcaatgtcg
     6241 attacatttt tcccgataca gacagcagat acaatattct tacatcggtt tcaccttgcg
     6301 atatagaaga taaacttaca aaacacaatg atgaaatcag acttgtaatc ataacctcgc
     6361 ctacatatga aggagttgtt tcggatataa agtcaatctc cgaaatctgt cacaaacacg
     6421 gagcaaaatt acttgttgac gaagctcacg gagcgcattt tccgttttca gacagttttc
     6481 ccgatgaagc acttaactgc ggtgcagacg cagcagtatt gagtctgcac aaaactttgc
     6541 cgtcattaac tcaaactgca ttgctcataa caaatgacag cgagctttct gaaattcttg
     6601 ccgaaaattt ggctgtattt gaaacaagca gtccgtcata tattttaatg agttcaatcg
     6661 aaaaatgcct tgatttctgc gaaaacagca aagataaatt caaggaatat tgttgcaatc
     6721 ttaaaacggt cagagaaaaa cttaaaaatc taaaatatct gaaaatttat gataaaagcg
     6781 atactgattt tgattatgat atcggcaaaa ttgtaatttc aacagcgaac gcaaatattt
     6841 cgggaacaaa gcttgccgaa atactgcgaa ataattatca gattgaaacc gaaatggcat
     6901 attcggacta tgtaattgcc atgacatctg tttgtgacac tgaaaaagct tttgatatgc
     6961 tttcagacgc tctgatttca attgacagcg aactttcaaa aggagccgac accgagcgtg
     7021 ttccgttaaa aaatctctac acaggcaaaa atttcaacgc ctgcgagttg tacaaattca
     7081 acaaagaaac tattccgttt caaaattcgg aattcagaac ttctgccgag tatatctggg
     7141 catatccacc cggaattccc ctcatcatac ccggtgaaat tataagcaag gaacttataa
     7201 attacattga atatctttca gcctgcaagg ttgagattat gtcaacaaaa ggcggtatga
     7261 cggacaacat aagcgtagtt aaaaaagatt gacaaatcaa tggctgtgtg ataatattaa
     7321 actaacaaaa tctaacaagg agtttgattt attatgaaga gaattaaaac tatcgaaact
     7381 cgtgacctca agaagagcgt taagacaggc ggttgcggcg agtgccagac ttcatgtcag
     7441 tcagcgtgta agacatcttg cggcgttgct aaccagcagt gtgaaaagtg catgagcgag
     7501 aaataattct attttaattt gattattaag gattatcgcc gttttcccaa agggttaacg
     7561 gctttccttt tgtctaacgg agatattatg attcatcagt ataaacttaa cggatacaac
     7621 atagttcttg atgtttacag cggcagtgta cacgcagtcg atgaccttgc ttatgatgtt
     7681 attgcaatgt acaaaaacgc aacaaaagaa cagataatcg acgaaatgct ttcaaaatat
     7741 gcagacaatc ctgagattac aaaagaagaa atctcagact gcattgatga tgtaaaagag
     7801 cttgagaaac agggaaagct ctttacagac gacaagtacg aaaaccttgc atttgacttt
     7861 aaaaagagaa acacagtaat caaagcactt tgtctgcaca ttgctcacac ctgtaacctt
     7921 aactgcgaat actgctttgc aagtcagggc aaataccacg gcgagagagc gctgatgagc
     7981 tttgaagtgg gcaagagagc aattgacttt ctcattgaaa attcaggcag cagagtaaac
     8041 cttgaggttg acttcttcgg cggagaacct cttatgaact ttgacgttgt aaagcagatt
     8101 gttgcctatg caagaagcat tgaaaaggaa cacaacaaaa acttccgttt tacacttaca
     8161 acaaacggta tgcttgttga tgacgatgta attgaatttg caaacaaaga atgtcataat
     8221 gtagttctca gccttgacgg cagaaaagaa gtgcatgacc atcttcgcaa aactgtaaac
     8281 ggcaagggca gttatgacat tatcgttccg aaattccagg aatttgtcaa aaaaagaggc
     8341 aacaagggtt actatgtaag aggcacttat acacataata acacagactt cacaaacgat
     8401 attttccata tggcggattt gggatttaca gagctttcaa tggagccggt tgtatgtgct
     8461 cccgatgacc catatgcact tacatatgac gatttgccta tcctttttga acagtacgaa
     8521 attcttgcaa aggaaatgct caagcgtgaa aaagagggca gaccgctcac cttctatcat
     8581 tatatgattg accttacagg cggtccgtgc atttataaga gaatctcggg ttgcggttcg
     8641 ggtacagaat atatggctgt aacaccttgg ggcgacctct atccctgtca tcaatttgta
     8701 ggcgatgaaa agtacaagct cggcgatatc tttaacggtg tttcaaacac gaaaattcag
     8761 gacgaattta agctttgtaa cgcatacgcc cgtcccgact gcaaagactg ctgggcaaga
     8821 ctttattgca gcggcggttg tgccgcaaac gcttatcatg caacaggctc aatcacaggt
     8881 atttacgaat acggctgtga gcttttcaga aaaagaatgg aatgtgccat tatgatgaag
     8941 gttgcagaag cagaaggata aaattacaat aaaatttaca ggcagataca tttttcttgt
     9001 atctgcctgt attttcgagg tgctgtatga acgaaaaaat tattatgctc ggcacaggaa
     9061 gtgcgatggt taccgactgt tataatacct gttttcttct gaaatccgaa aacgactgtc
     9121 ttcttgttga cgcaggcggc ggaaacggaa ttttatccgc aattaagaaa tccggagtag
     9181 cttggaacag cataaaaaca atgtttatta ctcattctca caccgaccat atattaggtg
     9241 ccgtgtgggt aataaggcaa ataagcgctc ttatgaattc aggcaaatat gacggtaatt
     9301 ttaatattta ctgccacgat gaatgtgttg attcaatcac ggcaatttgc aaccacacac
     9361 ttgcaccgaa atttctcaaa aatatcaata caaaaatttt catcaatgaa gtaaaagacg
     9421 gtgaaatgca aaatgccggc agtatccgac tcactttctt tgatatattt tcagacaaaa
     9481 caaagcaatt cggattcaag gctgtttttc cgtcaggaaa agttctcgcc tgtctcggtg
     9541 atgaaccgtt caatgaaaaa tgcagaaatt ttgttcaaaa ctgcgattat cttatgtgtg
     9601 aagctttttg tctttacagt caaaaagata tttttaagcc ctacgaaaaa ttccacagca
     9661 cagcgcttga tgcaggaaaa cttgcagaga gtctttttgc aaaaaatctt atcctgtatc
     9721 acaccgagga cgaaacactt caaacacgca aaaaaacata tacttcagag gcgagaacag
     9781 tttttaacgg aaatatattt gttcccgatg attttgaagt tattgactta aaataatctc
     9841 ataacacctg ctgtgattat acaaagcaca attcccattg cagtaggcaa agccatagaa
     9901 acaagcgtcc atttaaggct gcctgtttct ttttttattg tcagacaggt tgttgaacac
     9961 ggataatgaa gaatacaaag aataatcgtg catacagccg ttgtaatcgt ccagccgttc
    10021 atactgagaa gttgaaacag ctgatcgtag cttgaataat caacaagagt accgcttgcc
    10081 atatatgaca taattataat cggaataacg gtttcattcg caggaaatcc aagtataaat
    10141 gccattatta taacgccgtc aaccccgata aatctgccga acggatctaa aaaatcagta
    10201 cagtatttta aaagtgaaac atcgcttata tgcacatttg caagaatcca gattatcgca
    10261 cctgccggag cggcaaccgc aacagccctt cctaaaacaa ataatgttct gtccaacagc
    10321 gaacggacaa tagtttttaa aatctgcggc tttctgtacg gcggaagctc aagcacaaat
    10381 ccggactgtt cgcctttcaa tattgtgact gaaagtacct tagatataac aagtgttata
    10441 aaaacacaga aaactattat tccaatcaac aatgccgcta cctcaagcga actgctcagc
    10501 gtaaatgccg tacctgcaaa gaacatgagc agtaatgcaa tgattgtggg aaaccgtccg
    10561 ttacacggca taaaattatt tgtaagaatt gcaatcagcc gttcctttgg tgactcgatg
    10621 attctgcaac ccgtaactcc gcaggcatta cagccaagcc ccattgccat agcaagactt
    10681 tgctttccgt gtgcaccgca ctttgaaaaa tacctatcaa gattaaatgc aattctcggc
    10741 agatatcccg aatcctcaac aagtgaaaat agcggaaaga atatagccat aggcggcagc
    10801 attacagata ccacccatga cagagttgta taaactccgt caatcaaaag tcccgttaca
    10861 acatcgggag cgtgtaaaaa atcaaaaaga atatacagtt tctcttttat aaagccaaac
    10921 aaattgctta accattcgct cggataattt gcaccgacaa ccgttatcca gaacaatatg
    10981 ccaagcattg ccagcataat cggtattccc gtggttttgc ttgtaagtat tttatcaagc
    11041 tttcttgtac aagcatttaa ctctgatttt tcatatttta cgcagtcact tgaaattttg
    11101 ttgccaattt gcgaaagctt ttcaatattc tgtttgtagt ttttttcgga tagtatatca
    11161 acgccttcaa aatttctttc taccctaaaa cattttatct ttccgctgca tacattatag
    11221 atcgcttttt ttaattcatc caaacctttt ttgtctgttg cacaggtttt cacaacaggt
    11281 attccaagat ttagcgataa ctcgtcgcag tcgattttta taccgttttt ttcagcctca
    11341 tcacaaagat taagacaaag aacagcattc tttgtgacag ataacacctg caatgcaaat
    11401 gaaagatttc tttcaataac tccgcagtca acaactatta caacgcagtc attttgattt
    11461 tgtataagac actcccttgt taccgcctct tcgcccgaaa atgaaagcag ggaatagcat
    11521 cccggtaagt ccgtaataca aaatcttgcg tctttgattt tgcaacaacc tctggcaaac
    11581 tcaactgttt tacccgtcca gtttcccgtg tgctgtctta atcccgtcag ttcgttaaaa
    11641 attgtactct tgcctacatt aggattaccg gcaagtgaaa ttttgtaatc ccaatccgat
    11701 acatcctttt tattaaaaga tgatttatcc gtagaaaaca ataaaaaagc ctccttttat
    11761 tcaggagtaa caatgatatc tttgcaatcg ttatttctca gtgccacaac ggcattttta
    11821 acaagatacg cagacggatc accgaacgga cttgtaaaca aggggataac aggactgttc
    11881 tccataatac caaaatcaaa tattctgttt ttgatatttt cattacagtt cacacgatag
    11941 acaatccccg taactccaag cggtaacttg tcaagcgaac atttttcttt catctgattc
    12001 accgatttca actttttatt aacagcatat tcaattcata caactgagtt acacaaaaag
    12061 ccggccataa actaaactta tatcgtaccc gaataaactc tgatatcaga aaaattttaa
    12121 ggaattgaca cgactataaa caggtgttat aattaaatgc agatttcaaa tgtatataac
    12181 ttaatatggg tttacggttc aaaatgcatc ttgcagagta gataacagag aattcggtga
    12241 gaatccgaag caacagtcat tactgtattt ggcattgcca taagtcaggt cgctgtccgt
    12301 atacctcgga ttttgcaaat cttggacagg gaagaggtgc aaccgaccat atctgtacag
    12361 acttttggtc tgtatggttt tgtttgttgt gccttccaaa aaacggaagg cttttttatt
    12421 ttgcctttcg atatacacaa tacaatatgg aggaaaacac tatgaacaaa tcttttaaaa
    12481 aaatcctctc aattgtactt tctgtaatga tgatttcatc acttatgacg gtttcacttt
    12541 cagtaagcgc agttgaagac ggaaaagtaa gagtaattgt cagaaatgat acatactcag
    12601 tagaaaacgg cgctccgtgg gacggcgttc tcgttgatga gtgggtaagc attaataatg
    12661 acactactat gatgtcagcc gttgctgatg cactcaacaa tcacggctac acacaggaag
    12721 gtgctgagaa caattacatc tcatcaatta acggtcttgc tgcatttgac ggcggtacaa
    12781 tgagtggctg gatgggaact ctcaatgact ggttcacaaa ttcaggttat gcatcctata
    12841 cagtagcaga cggcacactt gagagtggtg atgaaatcgc tattatgtat acttcaaacg
    12901 gttacggcga ggatatcggc ggtacatggg caaataacga tacaactgtt aaatcggttg
    12961 agatcacagg tgccgagctt tcgggcgaat ttgatccgtc agttacagac tacacactca
    13021 caatcgacac tccgtcagct gatgtaaatg tagttcctac tgcaactaac aaaaacttcc
    13081 agacaagaaa atataagaat gaatatcttc cttctgacga cagtgcgttt tacaagagaa
    13141 gtcagactgt tagtgtttct gacggtgaca aaattatcat cggttgcggt gatactgcat
    13201 ggccgtcgat gaacacaagt gaaggcggta ctgtatatac attcacagtg aaatatgctc
    13261 cttccgcagc tgacacagtt tcaaacaaga ttgacgaggt tgcaaaacat cttgcatcac
    13321 aggatgcccc cacagtttct tcagtaggcg gcgagtggac agtcctcggt cttgcaagag
    13381 caggtaaaat cacagacgaa attgcagaca gttactatca gaatgcagtt aagtatgttg
    13441 aagaaaaggg ttctgcaaag cttcacaata ctaaatcaac agacaattca agagtaatcc
    13501 ttgcacttac ggcaatcggt aaggatgtta cagatgttgc atcatataac cttcttgaac
    13561 cgcttgcaga tatggattat gttaagaagc agggtatcaa cggtcctgtc tttgcactca
    13621 ttgcacttga tacgggcgat tatgaaattc cgcagacaga cgccgcaaat cccacaacaa
    13681 gagaaaagct cgtacagaca attcttgatg cacaggtagc aaacggtggc tggacattct
    13741 tcggctcaac tgcagatcct gatatgacag gtatggcaat tcaggcactt gctccttact
    13801 acacaacaaa cagcgatgtt aaagaggcaa ttgataaagc actcacagca atgtcaaacg
    13861 cacagaatga aaacggcgga tttgcatcat ggggttctgt aaacagcgaa agctgtgcac
    13921 aggtactcgt tgcacttaca agccttggaa ttgatcctac aaatgatgaa agattcatca
    13981 aaaacggcaa cacactcatc gatgctatga tgagtttctc cgctgaaaac ggatttggtc
    14041 atacagatac aacatacaat cagatggcaa ccgaacaggg tttctatgct tttgtttcat
    14101 ttgaccgtct tgtaaacggc aaaacttcac tctacaatat gactgaccga cttgcagaaa
    14161 attatgccgt aggtgatgtt aatcttgaca acacagtttc tgtaattgac gcaacactcg
    14221 ttcagaagca gattgtaaac cttgaacagc tttcaaaggt ttcacttatc aaagcagatg
    14281 taaatcatga cggtgttatc aatgttgttg atgcaacaga aattcagaaa atcatcgtta
    14341 acctcgtttg attaaagttc acaagtaaag attggttatg gaaaagataa aaaagtttgt
    14401 taaaaaaaat caaatacttt taattgcggt gtgcgtttgt attgccgcac ttacagtagc
    14461 attttttgca ggcggcaaca gatcggaaaa taaagttcaa actgcatcaa ctgcctcctc
    14521 gctatcgaca acaaatgcag acacagaaac aacttctgtg tctgcaacag agaaaaccac
    14581 tcaaaatcct accgattcca ctaaatcaaa caaagataaa aaggacaaaa aaaattccga
    14641 agataaaaag aacagtaagg ataattcgca gaacagtaac agttcagctg ttgaaaaaag
    14701 tgagaaatcc gagcagagtt caagcaacag ttcttcggat aagaaaaaac cgtcttcttc
    14761 atcaaacagt tcttcaaagc cgaacaaaaa gaatgatatt cagccgacaa cgcaggacaa
    14821 gtacaaaacc gatcccgtac cgtcgggaaa accaaagccg gttgaaccgg aagaacagga
    14881 aacaaaagat acaaatcttt attgtacctt tacaatcacc tgttcaacaa ttcttgacaa
    14941 catggatgac cttgatcccg aaaaaattga actcgttcca aaggacggta taatcctcaa
    15001 aaaacagaag gttcaattca aagagggtga atctgtatat gatgtccttg taaaagtttg
    15061 taaggacaac aatattcata tggaatcgag ctggactcct atgtataatt ccgcttatat
    15121 tgaaggaatt aacaacctct acgaatttga ctgcggttct ctttcgggtt ggatgtacaa
    15181 agtcaatgaa tggtttccaa actacggctg ttcacgatat gtactgaaaa acggcgacga
    15241 tgtggtctgg tgctacactt gtaacttagg ctatgatgtc ggcggaggat acgcaacagg
    15301 agaataatga tgaaggatac tttttcaaat atgcacccct ttatcaattt tatatttttt
    15361 gcacttacaa tagggttcac gatgtttatc atgaaccctg tttgtcttgc tgtaagtttt
    15421 ttatgtgcgc ttgtaaccgc tttatacctt aacggcaaaa atgctgtgag attgtcactt
    15481 gtttttcttt tacctatgat actcttgata gttctcgtaa atcctgtttt taatcatgaa
    15541 ggaatgacta tactcacata ttttccgtgg gataacccac taaccctcga atcaatcgtt
    15601 tacggtattg caagtgcatt cttgctttcg tcaacagttt tatggttttc ttcattcaat
    15661 gcagtaatca cttccgacaa ggtagttttc ctgtttggga gaataatgcc gtcattgagt
    15721 ctggtgattt caatggcatt gcgttttgtt ccaaggtttt cggcacaaat gaagcttgtg
    15781 cgtaatgcac aacacacaat cgggagagat atagacgagg gaacattgtt tcaaagaata
    15841 agaaatgctg taaaaatcct ttcgattatg ataacatggt cacttgaaaa cgcaattgaa
    15901 acagccgatt caatgaaaag cagaggtcac ggccttaaag gcagaacatc ctattcactt
    15961 tataaattcg acaaaagaga cgcatttatg ctttgcacaa tcctttttac cggattggta
    16021 cttatgattt tgctttttac aaacgcaata aaattcagat actatccgtc aatcaagggt
    16081 gatttgttta cggtgcaaag tgttattttt tatatattct acacattttt aatgttgatt
    16141 ccgctatcgg taaatatagg agaggggata aaatggaaac atatgcaatc aaaaatctga
    16201 gttttcgata ccccgaaacc ggtattgatg tacttaaaga tattactttc agcataaacg
    16261 agggcgagtt tatcacagtc tgcggtccgt caggctgcgg aaaaagcaca cttctcagac
    16321 atctgaaacc cgatctttca ccgcacggtg ttctttcggg agaaatattc tttgaagaaa
    16381 aacctatatc agacctttct cacagggagc aaagcagtaa aatcggtttt gttatgcaat
    16441 cacctgaaaa tcagattgtt accgataagg tatggcacga acttgctttc ggacttgaaa
    16501 gtcttggtta tgacaacaat acaatccgaa aaagagttgc cgaaacagct tcatttttcg
    16561 gaatccaaaa ttattttgaa aaaagtgttc tcgaactttc gggcggacaa aagcaaattt
    16621 taaaccttgc ttcaattatg gcaatgcaac cgtccgttct cattttggat gaaccgacaa
    16681 gccaactcga tccgattgcg gcaagcgaat ttttgcactg cgtttcgcgc ataaatcacg
    16741 aactggggac aacggtaata ataacggaac acagacttga tgaggtgctt ccgctttcag
    16801 acagggtgct tgtcatcgaa aacaacggaa tttcagcttt tgactctcct caaaaggtcg
    16861 ggaaaattct taaagaaaaa gacagtaaaa catttctttc tatgcctgct ccgatgcaga
    16921 tatggcaggc tgttacagaa aatgacaata ccgactgtcc cgtaactgtt ccaagcggca
    16981 aaaagtggct ttcggaatat gccaaaagtc ataaaatgta tgagctcaca cccgaaagca
    17041 ttcagaaaca ttctgataaa gaagcagtaa gtcttaatga tatttggttc aggtacgaaa
    17101 agtcgggtgc agatgtacta aaaggtcttt cactaaaaat atatcagggg gaatttgcgg
    17161 ctatactcag cggtaacgga atgggaaaat caaccgcttt gtcaattatc tgttcactta
    17221 acaagccata cagaggcaaa gttgaaatct ctccgcttaa caaaaattct tttgacacgc
    17281 tcgtagcagt attaccgcaa aatccgcaga cactgttttt gaaaaaaact gtacttgaag
    17341 atttatacga agtatttgac ggcagaaaaa tcagcaagga ggaaaaagaa agacgggtta
    17401 ccgcagcggt aaagctgtgc agacttgaaa gtctctgcaa tcgccatcct tatgatttat
    17461 ccggcggtga acagcagaga gcggctcttg caaaaattct tctcataagg cctcaaattc
    17521 ttttgcttga tgaacctaca aagggacttg atgccgaatt caagattgag tttgctcaga
    17581 ttatatacga cctcaataaa gccggcataa ccgttctcat ggtaagtcac gatgtagagt
    17641 tctgtgctgt atatccaagc cgctgtctga tgttttttaa cggtgaagtt gtgtcggaag
    17701 gtacaccgag aactttcttt tcgtcaaaca gcttttattc cacctctgca agccgaatgt
    17761 caaaaggcat aatagataac gcagaatcat caaatgatgt catatatgcc tgcacaggta
    17821 aaaacagaga tgttcaaatt aacagaaaca cacctgatat tgaccttttt aaaaacgaca
    17881 ccgaaaatat tccccaccaa aaaaacaaag ctgaaaacaa aaagctttct gtttttaaaa
    17941 aaatcttcgg attttttggc gcagtactgt tcatactcgg cctgattgta aatctggaat
    18001 atattccgaa tttttcagcc aaaactttgc ctacctggtt caactgggga ataatcggag
    18061 tatctgttgc gttgcttatg attgctttcg gaacaaaatc aaaacgaccg attgacctgc
    18121 cgagaaaaag ttcaaaactg agtaaaagaa ccgtcagtat ggcaattatg gttttgcttg
    18181 caattcctgt tacaattttt gttggaatga catatcttca ggatcagaaa tatcttttta
    18241 tttcactcct ggttatgatt gagtgtatga ttccgttttt tctcgttttt gaaggcaggc
    18301 acccaaaagc gagagagctt atcataattt ccgttctatg tgcaatagca gttgcaggac
    18361 gacttgcatt tacaatgttg cctcagttca agcccgttgt ggcaattgtg ataatttcgg
    18421 gagtagcatt cggtggtgaa tcgggatttc ttgtcggtgc tgtaagtatg cttgtttcaa
    18481 atcttatgtt cggtcaagga ccttggacgc cgtggcaaat gtttgcggca gggataatag
    18541 gcttcattgg cggtattctc tttaagaaag gtcttttggg cagaacaagg acttcgctct
    18601 gtatatacgg tttcattgcc acaatggtca tttacggcgg acttatgaac ctttattcgg
    18661 cactcacatc acattccgca tttaatctaa atatgctcat aactttttat gttcagggct
    18721 ttccgatgga tattgttcac gcagtttcga ctgttatatt tctgtttttc ggagcagaac
    18781 ctatgcttga aaagcttgac agaattaaag ttaagtacgg acttatcgaa taaacctaaa
    18841 cagcagataa aatttctgct gtttttttgt gctgtaattc aaaaattttc gacaaaagta
    18901 tagacataat ccgaaaataa tattataatt ttggtgtgtc tgattttaat caaacagtat
    18961 t
//
