LOCUS       c00061_gnlPro..        12593 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KHCMKGHB_61.
ACCESSION   c00061_gnlPro..
VERSION     c00061_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:07:16
            Original ID  :: gnl|Prokka|KHCMKGHB_61
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12593
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12593
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[312:3805]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      313..3805
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12593
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12593
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(2..298)
                     /locus_tag="ctg61_1"
                     /transl_table=11
                     /translation="MKSTLLNMTAVLFGITLVASAGVGFVNMITVEPIAAAKEAATLAA
                     LNEVLPAFDATTTEELTIDDMPITVYTATAGGSVSGYAVQSMTKQGFGGVVRLM"
     CDS             complement(313..1341)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_2"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 3.9e-115,
                     bitscore: 373.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKLIVAPAPHVQTAQSTTRIMRDVVIALMPALVVSTVVFGLDV
                     LRVTALSVVSCVVIEYLIQKFMVRGATTVGNWSAVVTGVLLAFNLPASIPWWIVVMGAF
                     VAIAVAKMTFGGLGKNPFNPALVGRVFLLIAYPVQMTTWPLPVNGSFDVLSGATPLAAV
                     KQGLAGPGAIGVQEMLLGNIPGSLGEVAAAALLCGFVYLLWRRVITWHIPVTVLATMAV
                     FAGVVAMCSVSFDALPQAADGTCSAGYKLGYLFGTAWRAGIFHVLAGGAMLGAIFMATD
                     YSTSPMTVRGGVIFAVGIGLITMCIRLWGAYPEGMSFAILIMNACVPLINKYVKPKRFG
                     VK"
     CDS             complement(1361..2692)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.5e-09, bitscore: 28.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4e-17, bitscore: 51.8,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.6e-53, bitscore:
                     168.8, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.1e-31, bitscore: 96.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.2e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGVHPSENKLSCAKPIEVLPLPDVVTIPLAQHIGAPAVAKVAKG
                     DRVLTGQLIAEAGSFMSANIHSPISGTVTAVDMVVNGQGLRQMMITIKREGDDWAEGID
                     RSDALVKVCPFSAQEIIAKIKDAGIVGMGGATFPTHVKLSVPPGKKAECVIINGVECEP
                     YLTSDHRTMLEHGEELVVGVTILMKAVGVGKAYIGIENNKPDAIAHLTKIAAGYKGIEV
                     VPLKVMYPQGGEKQLIAAVTGRQVPPPPALPIDVGAVVCNASTTVAVYQAVLKNKPLIE
                     RVVTVTGKSVKEPKNLLTRMGTPISALIEAAGGLPGDAGKVINGGPMMGRAMVNLDSPV
                     TKGCSGITVMSGRDAQRREATQCIKCAKCVSACPMGLEPYYLSKMTQKKGWDELEALMI
                     TSCIECGCCQSTCPAYLPLLDWVRLGKQTVMGLIRARAAAAPKK"
     CDS             complement(2906..3805)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1020:4Fe-4S binding domain (Score: 31.3; E-value:
                     4e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg61_4"
                     /sec_met_domain="Fer4_7 (E-value: 1e-11, bitscore: 35.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.4e-10, bitscore: 29.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.8e-09, bitscore: 26.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-12, bitscore: 37.4,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.8e-07, bitscore: 19.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVLLYTILTLCALGVFSAVILYFVARKFRVEEDPRIDEVEKMLP
                     GANCGGCGFAGCRGMADALVKRDDISALFCPVGGGDCMKAVAAYLGKAAAEKQPEVATV
                     RCGGTCEKRPRTNEYNGAKSCAVASSLYVGETGCAFGCLGFGDCVAVCAFDAIHINPET
                     GLPEVDADKCTACGACVKACPKMIIELRKKWPKNRAVYVSCVSKEKGAVVMKACKAGCI
                     GCGKCVKVCAFDAITVENNLAYIDPQKCKLCRKCVNECPTGAIRLVGMDPLPKAPKAPA
                     TPATPAAPKAGAAPKVEN"
     CDS             complement(3805..4224)
                     /locus_tag="ctg61_5"
                     /transl_table=11
                     /translation="VADLIEHCGVVERTERDTVYVRITSRSACGTCKARQACGLAEAQD
                     KIVAVATPEAGQYAAGREVMVGVRRSAGVRAVVLAYVGALAVLLAVLVGTIAVAGWSEG
                     AGALAAIAGVGVYYFALWLFRRKIEHTIQFTITKI"
     CDS             complement(4228..5808)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg61_6"
                     /sec_met_domain="NAD_synthase (E-value: 3e-68, bitscore:
                     219.2, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAIAQLNYTIGDVDGNASKIIDSIHKAKAQHADLVIFAEQAVS
                     GTPAFDLLRKTTFLELCEDALVEIASCCDGIAAIVGLPILTADGTISAAALIQDRKVLR
                     YIGKKYITARREMGFLVPSKGYEYATIKGHKCAIIVGDDLSRERDFDQSVETVISINAR
                     KYGKGTMTYRYEMMRNLAFVESKNLVLVNQVGGSTDIVYDGTSGALNSRGELVLMMKNF
                     EEDFQIFDTKASARPITIPSTYNDRTRLVYEAARCGLRDFFRKNGYRKASIGLSGGIDS
                     AVVASIAADALGAENVRALLMPSPFSSLESVEDAKELARNLGIEYNVIPISEIYTSVVN
                     TLKPVIGGTEFDATEENIQTRIRTVLLMALQNKTDYILLNSSNKSENALGLCTLYGDTA
                     GAFSPTGDLYKSEMYDVARYINRTQGNPIPESILTKEPSSELHPGQKDSDILPPYEVVD
                     AILFRMIEEGQHREEIVNAGFDSEVVEKIHGMIMRNEKKRYQFPPVLRLSSCTFGHERL
                     MPLTNKYGD"
     CDS             complement(5977..6738)
                     /locus_tag="ctg61_7"
                     /transl_table=11
                     /translation="MATQKKTADVDYSMQEKIMALYELQKIDSKIDEINKVKGELPLEV
                     QDLEDEMAGMKTRIEHINAEIEELNTLTKQRKREVDQAKIMIGNYKEQQNNVRNNREFD
                     AITKEIEYQELEIELAEKRLKEYSAGVKAKKLQLEEAENLSVERAADLAAKKAELEGIE
                     AETAPLVAEYAAQGERVKEKIDERLLAAYDRIRRNVRNGLAVVTVKRDACGGCFNRIPP
                     QRQVDIRQGKKIIICEYCGRILVADPDETQE"
     CDS             complement(6761..7546)
                     /locus_tag="ctg61_8"
                     /transl_table=11
                     /translation="MIIKQITDIIERFAPLEWQESYDNAGLIVGRPDDEVHKALLAVDV
                     TEEVLDEAEAEGCDLVITHHPIVFRALKRFNSADPVERCVERAIRSRIALYACHTNLDS
                     APGGMSWRLAEMLGVGNLRVLQPSETGDGAGFGVVGELPEAIDTVEFMRIIQRRLEVSV
                     IRYSDIATSGVRRVAVCTGAGASLIGEARRAGADIYITADMKYNDFMAPDKALTVADIG
                     HFESEYCAIQLIFDILSKNLCTFAVRKSERSRNPVNYLV"
     CDS             complement(7748..8359)
                     /locus_tag="ctg61_9"
                     /transl_table=11
                     /translation="MADKLFYSMGEVAEMFDVNTSLIRHWESQFSILRPKRNKKGNRLF
                     SPEDVENLKMIYHLVKERGMTLEGAKKALRKAPSESGVDRDAELMERLQRIRALLVEVR
                     EDLKAGEGEIVTASDADMTDADASAAAAADTAAAAETPVRRRRAKAVVKIDEPSDDAAG
                     KAAGDSSAQPAVKRSVRRPRRKKEEAETKELFAFYEQSLF"
     CDS             complement(8362..9786)
                     /locus_tag="ctg61_10"
                     /transl_table=11
                     /translation="MTLPAKFVERVLRDLGGTEGAALCAALDAEPPVSVRLNPAKTGAD
                     TLPAGPDAGLPVPEAAGLPALAIAGRVPWSRDGRYLAVRPSFTLDPDFHAGAYYVQEAS
                     SQFVGHLLAAVRTEGARILDLCAAPGGKTTLYASLAGPDGLVVANEIDRRRASVLADNV
                     RKWGTGNVAVTTCEPRALGDFEAWFDVVAVDAPCSGEGMFRKDPDARGEWSEGNVKQCA
                     ARQDEILREAWRALKPGGTLVYSTCTFNRDEDEGALERMAAWAGDEIAESEETAVEDAW
                     GIACGRVGAFRTFRFYPHRTCGEGFFAAVARKSFDAGGRVRAPKARRTVFAAVDRKTAG
                     ELARWVRNPGGMRFAAVADTCYAWYAAQADAVRTLSEALPVIYSGVALGQVFKGVLKPD
                     PALAFFDGLNRGALPAAELDDEETLRFLRRQDIAAGGLAEGMNLVCSRGRALGFAKRIG
                     ARVNNLYPNSLRIIKQ"
     CDS             complement(9790..10404)
                     /locus_tag="ctg61_11"
                     /transl_table=11
                     /translation="MYIAIAGNIGSGKTTLTQILTKRYDAKCYLEECDNPYIGDFYEDM
                     NRWAFNLQISFLGSRIQQTMGMISDCKSGVIFQDRTIYEDAHIFADNLHEMGLMATRDI
                     ETYMKIFRLVTTLIPKPDLLIYLKASVPTLISQIRKRGREYEMNIDELYLKRLNNKYNH
                     WIDTIYEGEVLVVDKDHEDFVSNPAVLERICARLDALKAKK"
     CDS             complement(10643..12118)
                     /locus_tag="ctg61_12"
                     /transl_table=11
                     /translation="MSFRNIILKAWFSQRERAIDRFRRRPVETQARMFRQLLRRGRFTE
                     FGDRYDLRHIRSVERFQSQVETFDYETFKPYIERMMEGVRSVTAPGRVSLFARSSGTTS
                     DRSKYIPVTMESLWWNHTLGMRDVATVFSANNPKTRVFEGKTLTLGGSCSREGRNLVGD
                     LSALLIHETTFWSGWFRAPRTETAIIPDFDEKCAAICRQCVGEPITAFAGVPSWNLALM
                     RRVLEYTGRKNLLEVWPGLEMFAHGGVEFAPYRTSFEELIPSEKMKYMETYNASEGFFA
                     MADDPSRSDMLLMLDYGTFFEFRSGTQIVPLEGVECGKVYAVLITSNNGLWRYEIGDTV
                     EFTSTNPYRIRFAGRTRQYINVFGEELIVDNAEHALLAACRKTGAVVSEYSVAPCYMSL
                     RERGAHEWIVEFEREPDSLERFAEALDGELRAVNSDYDAKRRTTLERQRLTVVERGRFL
                     AWMRARGKNKVPRLVNDRRVADEILAFQTEQTL"
     CDS             complement(12162..12593)
                     /locus_tag="ctg61_13"
                     /transl_table=11
                     /translation="GRSETNILAAMLAKRMGVKKVIAEVENLNYINLAESIGIDTIINK
                     KLVTASNIFRFTMSTDVQAIKCLTGSDAEVLEFIVKPNSPATKVRIKDLGLPEDTIIGG
                     IVRGDKVFIAVDNMEIIPYDRVVVFAMPGSVGKVGYYFN"
ORIGIN
        1 ccatcaggcg caccacgccg ccgaagccct gcttggtcat cgactgcacg gcataaccgc
       61 tcacgctgcc cccggccgtc gccgtgtaaa ccgtgatcgg catgtcatcg atggtcagct
      121 cctcggtcgt cgtggcgtcg aacgccggaa gcacctcgtt cagggccgcc agcgtcgcgg
      181 cttccttggc cgccgcgatc ggctccacgg taatcatatt gacgaagccc actccggccg
      241 aagccacgag ggtgatgccg aagaggacgg ccgtcatgtt caaaagtgta cttttcatgc
      301 tgtcacctcc tcttatttca cgccgaagcg cttgggtttg acatatttgt tgatcagggg
      361 cacgcaggcg ttcataatca ggatcgcaaa cgacatgccc tcgggataag cgccccacag
      421 acggatgcac atggtgatca gtccgattcc cacagcgaag atcacgccgc cccgaacggt
      481 catcggcgag gtcgaatagt ccgtggccat gaagatcgca cctaacatcg cgccgcccgc
      541 aaggacatgg aatataccgg ccctccacgc agtcccgaag aggtatccca gtttataacc
      601 ggccgaacag gttccgtcgg cagcctgcgg aagcgcgtcg aacgacacgg agcacatcgc
      661 aaccaccccg gcgaacacag ccatcgtcgc gagcaccgtc acgggaatgt gccacgtgat
      721 cacgcgccgc cacagcaggt agacgaatcc gcacagcaag gccgcagcgg ccacctcgcc
      781 cagcgaaccg gggatgttgc ccagcagcat ctcctgcacg ccgatggcgc cgggacccgc
      841 cagcccctgc ttcacggccg ccagcggcgt ggcgcccgac agaacgtcga acgagccgtt
      901 cacgggcagc ggccaggtgg tcatctgcac cggataggcg atcagcagga acacgcgtcc
      961 caccagcgcg gggttgaagg ggttcttgcc caggccgccg aaggtcattt tggcgacggc
     1021 gatggccacg aaggcgccca tcacgacgat ccaccaggga atcgacgccg gaaggttgaa
     1081 ggcaagcagc acgcccgtca ccacggccga ccagttgccg acggtagtcg caccgcggac
     1141 catgaatttc tgaatcaggt actcgatcac cacgcacgac accacggaaa gggccgtaac
     1201 gcgcagcacg tccagtccga agaccaccgt cgacacgacc agcgcgggca tcagcgcgat
     1261 cacgacgtcg cgcatgatcc gggtcgtcga ctgggccgtc tgcacgtggg gtgcgggagc
     1321 cacaatgagt ttattagcca tatctatact gttttttcat ttacttttta ggtgcagccg
     1381 ctgcgcgtgc gcggatcagg cccatcacgg tctgcttgcc gaggcgcacc cagtccagca
     1441 gcggcagata ggccggacac gtcgactggc agcagccgca ctcgatgcac gaggtgatca
     1501 tcagcgcttc cagttcgtcc cagcccttct tctgggtcat cttcgagagg taatagggtt
     1561 ccagtcccat cggacaggcg gagacgcact tggcgcactt gatgcactgc gtcgcctcgc
     1621 ggcgctgtgc gtcgcggccc gacatgacgg tgatgcccga gcagcccttc gtcacgggcg
     1681 agtcgaggtt caccatcgcc cggcccatca tcggaccgcc gttgatcacc ttgcccgcat
     1741 ccccgggaag gccgcccgcg gcctcgatca gcgccgagat cggcgtaccc atgcgggtca
     1801 gcaggttctt cggctccttc acgctcttgc ccgtgacggt caccacccgc tcgatcagcg
     1861 gtttgttctt cagcacggcc tgatagacgg caacggtcgt cgaggcgttg cacaccacgg
     1921 cccccacgtc gatcggcagc gcgggcggag gcggaacctg acggcccgtg acggctgcga
     1981 tcagctgttt ctcacccccc tgcgggtaca tcaccttcag gggtacgacc tcgatgccct
     2041 tgtatccggc ggcgatcttc gtcagatgcg cgatcgcgtc gggtttgttg ttctcgatgc
     2101 cgatataggc tttcccgacg cccacggcct tcatcagaat cgtgacgccg acgaccagtt
     2161 cctcgccgtg ctccagcatc gtgcggtggt ccgacgtaag atagggttcg cactccacgc
     2221 cgttaatgat gacgcactcg gccttctttc cgggaggaac cgagagtttc acgtgcgtgg
     2281 ggaacgtcgc gccgcccatg ccgacgatgc cggcgtcctt gatcttggcg atgatctcct
     2341 gcgccgagaa ggggcagacc ttcaccagcg cgtccgaacg gtcgatgccc tcggcccagt
     2401 cgtcgccctc gcgcttgatg gtgatcatca tctggcgcag gccctggccg ttgacgacca
     2461 tatcgacagc cgtcaccgta cccgaaatcg gggagtggat gttcgccgac atgaaactgc
     2521 cggcttcggc gatgagctgg cccgtgagca cccgatcgcc tttggcgacc ttggccaccg
     2581 ccggggcgcc gatgtgctgt gcgaggggaa tcgtcaccac atcgggcagc ggcagcacct
     2641 cgatcggttt ggcgcagctc aacttatttt ccgacggatg gactccgccc attggaaatg
     2701 ttctcataga tatagtaagg ttctattttt atgcttctgc ttcgaaaaac ctgtgtcgtt
     2761 tttccttatc cgcaggtcgt gatcgcggcg caacgccgcg tttatacatt tgacccacct
     2821 ctaaatcccc gccttgacgg gaacttatcg cccgcgaccg gattgtcaac cggaatgcgg
     2881 atggaaaagt ctcaactcgt ctctttcagt tttcaacttt cggcgcagcc ccggccttcg
     2941 gagcggcggg tgttgccggt gttgccggag ccttcggggc tttgggcagc gggtccatgc
     3001 cgacgagccg gatggctccc gtaggacatt cgttcacaca cttgcggcac agcttgcact
     3061 tctgcgggtc gatgtaggcg aggttgttct ccacggtgat ggcatcgaag gcgcatactt
     3121 tcacacactt gccacagccg atacatccgg ccttgcaggc cttcatcacc acggccccct
     3181 tctccttcga cacgcacgac acgtacaccg cacggttctt gggccatttc ttccgcagtt
     3241 cgatgatcat tttcggacac gccttcacgc aggcgccgca ggccgtgcac ttgtcggcgt
     3301 cgacctccgg aagtcccgtt tccgggttga tgtgaatggc gtcgaaggcg cagaccgcga
     3361 cgcagtcgcc gaagcccaga cagccgaacg cgcagcccgt ctcgcccaca tagagcgacg
     3421 aagccacggc acacgacttg gccccgttgt actcgttggt gcggggacgc ttctcgcacg
     3481 tgccgccgca gcggacggtc gccacttcgg gctgcttttc ggcagcggcc tttccgaggt
     3541 atgcagccac ggctttcata cagtcgccgc cgcccacggg gcagaagagc gccgagatgt
     3601 cgtcgcgctt cacgagcgcg tcggccatgc cccggcatcc tgcgaatccg cagccgccgc
     3661 agttggcccc ggggagcatc ttctccacct cgtcgatccg cgggtcctcc tcgacccgga
     3721 atttccgggc cacgaaatag aggattaccg ccgagaacac tcccagcgca cacagcgtca
     3781 ggatcgtgta aagtaatact tccatcagat ttttgttatt gtaaattgaa ttgtgtgttc
     3841 gattttccgc cggaagagcc acagcgcgaa ataataaacg cccacgcccg caatagcggc
     3901 gagggcgccc gcaccttcgc tccatccggc gacggcgatc gtcccgacca gaacggccag
     3961 caggacggcc agcgcaccga cataggccag cacgacggcg cgtacgccgg cactccgccg
     4021 cacgccgacc atcacctccc tgccggcggc atactgcccg gcctcggggg tcgccacggc
     4081 gacgatcttg tcctgcgcct cggccaggcc gcacgcctgg cgggccttgc aggttccgca
     4141 ggcgctccgg gaggtgatcc tcacatagac cgtgtcgcgc tccgtgcgtt ccaccacgcc
     4201 gcagtgttcg atcaaatccg ccacgcccta atctccgtat ttgttggtga ggggcatcag
     4261 ccgctcatgt ccgaacgtgc acgacgagag ccgcagcacg ggcggaaact ggtagcgttt
     4321 cttctcgttg cgcatgatca tgccgtgaat tttctccacc acctccgagt cgaagcccgc
     4381 gttgacgatc tcctcgcggt gctgcccctc ctcgatcatg cggaacagga tggcgtccac
     4441 cacctcgtag ggcggcagaa tgtcgctgtc cttctgtccg ggatgcagtt ccgacgaagg
     4501 ttccttggtc aggatgcttt cgggaatcgg gttgccctgc gtccggttga tatagcgtgc
     4561 cacgtcgtac atttcgctct tgtaaaggtc gcccgtgggg ctgaaagcgc ctgccgtgtc
     4621 gccgtacagg gtgcagagcc ccagtgcgtt ctcgctcttg ttcgaggagt tcagcaggat
     4681 gtagtccgtc ttgttctgga gggccatcag cagcaccgtg cggatacgcg tctggatatt
     4741 ctcctccgtg gcgtcgaact ccgtgccgcc gatgaccggc ttgagggtgt tcaccacgct
     4801 ggtatagatt tccgagatcg gaatgacgtt gtattcgatg ccgaggttgc gcgccagctc
     4861 cttggcgtcc tccaccgact cgagggacga gaagggcgag ggcatcagca gcgcgcggac
     4921 attctccgcc cccagcgcat cggcggcgat cgaggccacc acggccgagt cgatgccgcc
     4981 cgaaaggccg atcgaagcct tccggtagcc gttcttgcgg aagaagtccc gcagtccgca
     5041 gcgtgccgcc tcgtagacca gacgcgtgcg gtcgttgtag gtcgagggga tcgtgatcgg
     5101 ccgggcggac gccttcgtat cgaaaatctg gaaatcctcc tcgaaattct tcatcatcag
     5161 caccagttcg ccgcggctgt tcagcgcgcc cgacgtgccg tcgtagacga tgtcggtcga
     5221 accgcccacc tgattgacca gcacgagatt cttgctctcg acgaaagcca ggttgcgcat
     5281 catctcgtaa cggtaggtca tggttccctt gccgtatttg cgggcgttga tcgagatgac
     5341 cgtttcgacc gactggtcga agtcgcgctc gcggctcaaa tcgtcgccca cgatgatcgc
     5401 gcacttatgg cccttgatcg tggcgtattc atagcctttc gaagggacca ggaaacccat
     5461 ttcacggcgc gccgtgatgt atttcttgcc gatgtagcgc agcaccttgc gatcctggat
     5521 cagcgccgcg gcgctgatcg tgccgtccgc cgtgaggatc ggaagaccga cgatggcggc
     5581 gatgccgtcg cagcacgagg ctatttcgac cagagcgtcc tcgcagagtt cgagaaaggt
     5641 cgtcttgcgc agtaggtcga aggcgggggt tccgctcacg gcctgttcgg cgaaaatcac
     5701 caggtcggca tgctgcgctt tcgccttgtg aatggagtcg atgatcttcg aggcattgcc
     5761 gtccacgtct ccgatcgtgt aattcagctg agctatggct attttcatgc gaataattta
     5821 agtccggaaa ttacaacttt gcaaagttaa ggattatttg caaaagtcgg aaagattttc
     5881 gatgttaata aattaacatt cccgcattta caaaaatatt taaaaacaaa aaaggctccc
     5941 ggttttccgg aagccttttc gctgttcgta tcgtctctat tcctgcgttt cgtcgggatc
     6001 ggcgacgagg atgcggccgc agtattcgca gatgatgatc ttcttgccct ggcggatgtc
     6061 tacctgacgc tggggcggga tgcggttgaa gcagcctccg caggcgtcgc gcttgacggt
     6121 caccaccgcc agtccgttgc ggacgttgcg gcggatacgg tcgtaagccg ccagcagacg
     6181 ctcgtcgatc ttctccttga cacgctcgcc ctgtgcggcg tattccgcca ccagcggagc
     6241 cgtctcggcc tcgatgccct ccagttcggc cttcttggcc gcgaggtcgg cagcgcgctc
     6301 tacggagagg ttctcggcct cctccagctg gagtttcttg gccttcacgc cggcggaata
     6361 ctccttcagg cgcttctcgg ccagctcgat ttcaagctcc tgatactcga tctccttggt
     6421 gatggcgtcg aactcgcggt tgttgcgcac gttgttctgc tgctccttgt agttgccgat
     6481 catgatttta gcctggtcca cctcgcgctt gcgctgcttg gtcagcgtgt tcagctcctc
     6541 gatctcggcg ttgatgtgtt cgatgcgggt cttcatcccg gccatctcat cctcgaggtc
     6601 ctgaacctcg agaggcagtt cgcctttcac cttgttgatt tcgtcgatct tgctgtcgat
     6661 cttctgcagc tcatagagcg ccatgatctt ctcctgcatc gaataatcga cgtcggccgt
     6721 cttcttttgc gttgccatat gttgtcttta tagtttagac ttaaaccaga tagtttaccg
     6781 gattgcgcga gcgttcactc ttgcgaaccg caaaggtaca taaatttttc gataaaatat
     6841 caaatattaa ttgaattgcg caatattcgc tttcgaaatg acctatatcc gccaccgtga
     6901 gggccttgtc gggcgccatg aagtcgttgt acttcatgtc ggcggtgatg tagatgtcgg
     6961 ccccggcacg gcgcgcttcg ccgatcagcg aggccccggc cccggtgcag accgccacgc
     7021 ggcgcacccc ggatgtcgct atgtcactgt accgtatgac gctcacctca agccgccgtt
     7081 ggatgatccg cataaattcc acggtgtcaa tggcttccgg cagttcgccc acgacgccga
     7141 accccgcgcc gtccccggtc tccgaaggct ggaggacccg aaggttcccc acgcccagca
     7201 tttcggccag ccgccagctc atgcccccgg gggcgctgtc gaggttggtg tggcaggcgt
     7261 agagcgcaat ccggctgcgg atggcccgct cgacgcaccg ctcgacggga tcggccgagt
     7321 tgaaccgctt gagcgcgcgg aagacgatcg gatgatgtgt gatcaccaga tcgcaccctt
     7381 cggcttcggc ctcgtccagc acctcttcgg taacatccac ggccagcagg gccttgtgca
     7441 cctcgtcgtc ggggcggccg acgataagtc ccgcattgtc atacgattcc tgccactcaa
     7501 gtggggcaaa gcgttcgata atgtcggtta tttgtttgat aatcatatga gttaattata
     7561 ttatacagca ttcaggagtt cttcgccgcc tgcacctgcg cttttagccg gtctgtcgct
     7621 tcgcggcatt acgccccgcc gaggcggggg cttgcgaaga cggcggcaca ccgtgaatac
     7681 gcccggtaaa gccgcgaatc cttgaacaat accccgcgcg gatcgagaac gtctttacgg
     7741 acaatgctca aaataaggat tgttcgtaaa acgcgaacag ctctttggtt tcggcctcct
     7801 ccttcttgcg gcggggcctg cggacgctgc gtttgacggc aggctgcgcc gaggaatccc
     7861 cggcggcttt cccggcggca tcgtccgacg gttcgtcgat cttcaccacg gccttggccc
     7921 ggcgacggcg cacgggcgtt tcggcggcgg cagcggtatc agcggcggca gcagcggagg
     7981 catcggcatc ggtcatgtcg gcatccgaag cagtcacgat ctcaccctcc ccggctttca
     8041 ggtcctcgcg aacctcgacc agcagggcgc ggatacgctg caaccgctcc atcagttcgg
     8101 catcacggtc cacgccgctc tcggagggcg ccttccggag cgccttcttg gccccttcga
     8161 gcgtcatgcc gcgctccttg accaggtggt agatcatctt gaggttctcg acgtcctccg
     8221 gcgagaagag gcggttgcct ttcttgttgc gcttggggcg gagaatgctg aactgcgact
     8281 cccagtggcg gatcaacgac gtgttgacgt cgaacatctc ggccacctcg cccatcgaat
     8341 aaaaaagttt atcggccata tctattgttt tataattcgc aatgagttgg gatacaggtt
     8401 attcacccgt gcaccgatcc gtttggcgaa tcccagcgca cgcccccgcg agcagacgag
     8461 gttcatcccc tcggccaacc ctccggcggc gatgtcctgc cggcgcagga agcgcagcgt
     8521 ctcttcgtcg tccagttccg ccgcaggcag cgccccgcgg ttcagcccgt cgaaaaaagc
     8581 cagcgcggga tcgggtttca gcactccctt gaacacctgc cccagcgcca cgcccgaata
     8641 gatcacgggc aacgcctcgg agagcgtccg cacggcgtcg gcctgcgcgg cgtaccatgc
     8701 atagcaggtg tcggccaccg ctgcgaagcg cataccgccg ggattccgca cccagcgggc
     8761 cagttcgccg gcggtcttcc ggtccacggc cgcaaatacc gtgcgacgcg ccttcggcgc
     8821 gcgcacgcgc cccccggcgt cgaacgattt gcgggccacg gcggcgaaga acccttcgcc
     8881 gcaggtccgg tggggataga accggaacgt gcggaacgct ccgacacgcc cgcaagcgat
     8941 gccccacgca tcttccacag ccgtttcttc cgactcggcg atctcgtcgc cggcccacgc
     9001 cgccatccgc tccagcgcgc cttcgtcctc gtcgcggttg aacgtgcagg tgctgtaaac
     9061 gagcgtgccg cccggtttca aggcccgcca cgcctcgcgc aggatttcat cctgccgcgc
     9121 ggcgcactgt ttcacgttgc cttcgctcca ttcgccgcgg gcgtcggggt ccttgcggaa
     9181 catcccctcg cccgagcagg gggcatcgac ggccaccacg tcgaaccacg cctcgaaatc
     9241 gcccagcgca cgcggctcgc aggtcgtgac ggccacgttg cccgtgcccc acttgcgcac
     9301 gttgtccgcc agcaccgagg cgcggcggcg gtcgatctcg ttggcgacga ccagcccgtc
     9361 gggtccggcc agcgaggcgt agagcgtcgt cttgccgccc ggagccgcac acaggtcgag
     9421 gatgcgcgcc ccttcggtgc ggaccgcagc gagcaggtgt cccacgaact gcgacgaagc
     9481 ctcctggaca tagtaggccc cggcatggaa gtcgggatcg agcgtgaagg agggacgcac
     9541 ggcgaggtaa cgcccgtcgc ggctccacgg cacgcgcccg gcgatcgcca gagcgggaag
     9601 ccccgcagcc tccggaacgg gaagcccggc gtcaggtccg gcgggaagcg tgtccgcccc
     9661 ggtcttggca gggttcagcc gcaccgatac cggcggctcc gcgtcgagcg ccgcgcagag
     9721 ggccgcgccc tccgtcccgc cgaggtcgcg caggacccgc tccacgaatt tcgcaggcag
     9781 cgtcatgcgc tatttcttcg ctttgagcgc gtcgaggcgc gcgcagatcc gttccagcac
     9841 cgcagggttc gagacgaaat cctcgtggtc cttgtccacg acgagcacct cgccctcgta
     9901 aatggtgtcg atccagtggt tgtatttgtt gttcagccgc ttgaggtaca gttcgtcgat
     9961 gttcatctcg tactcgcggc cgcgcttgcg gatctgcgaa atgagcgtcg ggacgctcgc
    10021 cttgaggtag atcagcaggt caggtttggg aatgagcgtc gtcaccagcc ggaaaatctt
    10081 catgtaggtc tcgatgtcgc gcgtggccat cagccccatt tcatgcaggt tgtcggcgaa
    10141 gatgtgcgca tcctcgtaga tcgtgcggtc ctggaagatc acccccgact tgcagtcgga
    10201 gatcatgccc atcgtctgct ggatgcggct cccgaggaac gaaatctgaa gattgaacgc
    10261 ccagcggttc atatcctcgt agaagtcgcc gatataggga ttgtcgcact cctcgaggta
    10321 gcacttggcg tcgtagcgct tcgtaaggat ctgggtaagc gtcgtcttgc cgctcccgat
    10381 gtttccggct atggctatgt acatggcagt ataggtgtta ttttacgttt ctcattcgtt
    10441 ttccggtctc cgaagcgcat atcccgccgc cttcggcctc gttttacaag cctgactcca
    10501 cccggctaaa agccgggatt caggggcgat gcaaagtcac tgcacccgga ctcaattcca
    10561 cgcttccatt cccaaaagcc gtttcttaaa cggccctcgg gtggggcttc tcgcagcgcg
    10621 gccaaaatgc ggacagacag cctcaaaggg tctgttcggt ctgaaaagcc agtatctcgt
    10681 cggccacgcg gcggtcgttc accagccgcg gaaccttgtt tttaccccgc gcgcgcatcc
    10741 acgcgaggaa ccgcccccgc tccacaaccg tcagacgctg gcgttcgagc gtggtccgcc
    10801 gcttggcgtc gtagtccgaa ttgacggccc gcaactcccc gtcgagcgcc tcggcgaaac
    10861 gttcgaggct gtccggctcg cgttcgaact ccacgatcca ctcgtgcgcg ccccgttcgc
    10921 ggagcgacat gtagcacggc gcgacgctgt attcgctcac gacggccccc gtcttccggc
    10981 aggcggccag cagcgcatgt tcggcgttgt cgacgatcag ctcctcgccg aaaacgttga
    11041 tatactgccg cgtgcggccc gcgaagcgga tgcggtaggg attcgtcgag gtgaattcca
    11101 ccgtgtcgcc gatctcgtaa cgccacaggc cgttgttcga ggtgatcagc acggcgtaga
    11161 ccttgccgca ctccacgcct tcgagcggca cgatctgcgt cccgctgcgg aactcgaaga
    11221 aggttccgta atccagcatc agcagcatgt cgctgcgcga cgggtcgtcg gccatggcga
    11281 agaatccctc cgaagcgttg taggtctcca tgtatttcat cttctccgaa gggatcagct
    11341 cctcgaacga cgtccggtag ggcgcgaact ccacgcctcc gtgggcgaac atctccagcc
    11401 cgggccacac ctccagcaga tttttccggc ccgtatactc cagcacgcgg cgcatcagcg
    11461 cgaggttcca tgacgggacg cccgcaaagg ccgtgatcgg ttcgccgacg cactggcggc
    11521 agatggcggc gcacttctcg tcgaaatcgg gaatgatcgc cgtctcggtc cgcggcgccc
    11581 gaaaccagcc gctccagaag gtcgtctcgt ggatcagcag cgccgagagg tcgccgacca
    11641 ggttgcggcc ctcgcggctg cacgacccgc cgagcgtcag ggtcttgccc tcgaaaacgc
    11701 gggtcttcgg attgttggcc gaaaagaccg tcgccacgtc gcgcatgccc agcgtatggt
    11761 tccaccacag cgactccatc gtcacgggaa tgtatttgct cctgtcggag gtcgtgcccg
    11821 acgaacgggc gaacagcgac acccgacccg gagccgtgac gctccgcacg ccctccatca
    11881 tccgttcgat atagggcttg aaggtctcgt agtcgaaagt ctccacctgc gactggaacc
    11941 gctccaccga acggatatgc cgcaggtcgt agcggtcgcc gaactccgtg aagcgtcccc
    12001 ggcgcagcag ctgccggaac atccgcgcct gcgtctcgac aggacggcgg cgaaaacggt
    12061 cgatggcccg ctcgcgctgc gagaaccagg ctttgagaat tatgtttcga aaagacatga
    12121 tgcgctgcaa ttcagaattg tgaattctga attgtgaatt cttaattaaa ataatacccg
    12181 accttcccca ccgaaccggg catggcgaag accaccacgc ggtcgtaggg gattatttcc
    12241 atgttgtcga cggcgatgaa aaccttgtcg ccgcggacga tgccgccgat gatcgtatcc
    12301 tccggcagcc cgaggtcctt gatccgcacc ttcgtggccg gggagttggg tttcacgatg
    12361 aactccagca cctcggcgtc gctccccgtc aggcatttga tggcctgcac gtcggtcgac
    12421 atcgtgaagc ggaaaatgtt cgacgcagtc accagcttct tgttgatgat cgtgtcgatg
    12481 ccgatcgact cggcgaggtt tatgtaattg agattctcga cctcggcgat caccttcttg
    12541 acccccatgc gcttggcgag catcgccgcc aggatgttgg tctcgctgcg ccc
//
