LOCUS       c00004_gnlPro..        17127 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NBDFPNLB_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 03:46:42
            Original ID  :: gnl|Prokka|NBDFPNLB_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17127
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17127
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4135:7127]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4136..7127
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17127
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17127
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             789..2006
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:Iron-containing alcohol dehydrogenase (Score:
                     335.1; E-value: 1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="Fe-ADH (E-value: 2.8e-102, bitscore:
                     335.1, seeds: 219, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARFTLPRDLYHGKGALEALKSFTGKKAMICVGGGSMKRFGFLDR
                     AVEYLKEAGMEVELFEGIEPDPSVETVMRGAEAMLKFEPDWIIAMGGGSPIDAAKAMWI
                     KYEYPEITFEEMCKVFGIPPLRRKAHFCAISSTSGTATEVTAFSIITDYQKGIKYPIAD
                     FEITPDVAIVDPDLAETMPKKLVAHTGMDAMTHAVEAYVSTAHCDYTDPLAIFAIRMIQ
                     GDLVDSYNGDMSKRDSMHNAQCLAGMAFSNALLGIVHSMAHKTGAAFADYGAHIIHGAA
                     NAMYLPKVIAFNAKDPEAKKRYGVIADEMKLGGANDDEKVKLLIEYLRGMNDALNIPHC
                     IQHYGPDSYPTEQGFVPENVFLERLPEIAKNAIADACTGSNPRQPSQEEMEKLLKCCYY
                     DTEVDF"
     CDS             complement(2166..3563)
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MQIFNTLTRQKEEFVPQVPGEYRIYVCGPTVYNYIHIGNARPLIV
                     FDTLRRYLEYRGNKVIYVSNITDIDDKLIKKGQEEGTSMKEVAQRFEAEYLKDAAGLNC
                     EKPTVQPRATEHIPQILDIVKDLIDSGHAYVAKNGDVYFRVKSDPGYGKLSHLNLDDLE
                     SGNRELRSRMEDDLKEDPADFAVWKAAKPGEPAWESPYGMGRPGWHIECSAMSRTHLGK
                     TIDLHCGGQDLIFPHHENEIAQSECANGCEFARYWMHNGFINVDNQKMSKSLHNFFTVR
                     DVANLYGYEPIRYFMLTAGYRMPLNYTVDLIESCKNSLERLYTCRENLDFALSKTDFGT
                     DETLKEKAAEARTKFCTAMDDDLNTPDALAAVFDLVKEINTLSAASSKAALETAAAAFD
                     EITGVLGLLYNRKKDEVPAEVTALVEKRAAAKKAKDWATADAIRAQLTELGWAVKDTAQ
                     GPQLSKL"
     CDS             complement(4136..4888)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 62.6;
                     E-value: 1.5e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-29, bitscore:
                     96.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASCKTLGYVHSLESFGSVDGPGVRFVVFLQGCALRCKYCHNPET
                     WAEGGEAWTAEALFQRVYRYRNYWGKKGGITVSGGEPLRQLDFLTEFFTLARAKGVHTA
                     LDTAGQPFRPDDPAYLAAFDRLMANTNLVILDLKEIDPERHRQLTGKDNANILAMARHI
                     SDLGIPLWIRHVLVPGLTDDEEGLRKTADFIRSLKTVQRVEVLPYHTLGLFKWQKLGIP
                     YPLPDAVPPTAEQVKRAEELLEVSRYPG"
     CDS             complement(4875..7127)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-40, bitscore:
                     131.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 5.6e-267, bitscore:
                     879.9, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQFEQWEGFEGRIWKEEVNVRDFIQKNYTPYDGDESFLAGPTEA
                     TDKLWGALQQLQKAERAKGGVLDMETEVVSSLTSYGPGYIDENLKDLEQIVGLQTDKPL
                     KRAFMPYGGIKMAEQACTTYGYQPSAELHKIFTDYTRTHNQAVFDAYTPEMKKARHTHI
                     ITGLPDTYGRGRIVGDYRRVALYGIDALIQFKQEDLANCGDGTMTDDVIRLREEIARQI
                     SALKGMKKMAEAYGYDISQPAKDAKEACQWLYFGYLAAIKTQNGAAMSVGRISTFLDIY
                     IQRDLDKGILTESEAQELIDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVGGIGMDG
                     RSMVTKNCYRFLHTLENMGPAPEPNLTVLYSSALPENFKKYAAKVSINTSSVQYENDDV
                     MKPVWGDDYSICCCVSATQTGKEMQFFGARANLAKCLLYAINGGVDEKSHEQCGPNYAP
                     ITSEYLTYDEVLPKYVQMLDWLAGLYVNVLNLIQYMHDKYYYEEAEMALIDTDVRRTFA
                     TGIAGFSHVIDSLSAIKYAKVKVVRDESGLATGFETEGDFPKYGNDDDRADEIGVWLLK
                     TFLEMIKKRHTYRNSEATTSILTITSNVVYGKYTGALPDGRAAFTPFAPGATPSYGAEQ
                     NGLLASLNSVAKLPYHWALDGISNTQTINPEALGHSEDERVENLVQVLDGYFDQGAHHL
                     NVNVFGKEKLLDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVLARTCHGVL"
     CDS             complement(7705..8163)
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKSFHIPRTALFFILFALAAFAVLYRPIDLKALVRASSQGTLRTE
                     EVAHFGSTNDMDYHLLSMDSEEFQQTAELLSTVSCRKKLNQNYSAYTHDTFPVQSVTVS
                     FYDDAENQKFLLTVYSDGVCILNSAFVSVKYPGGGAAQLYEQLAGMGQ"
     CDS             complement(8168..9205)
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MSQAAAQQPSRKKAVISLLVLLALTCIIVFTFKDHWAEITAALAQ
                     LSVWQVLAVLAVGISYPLLEGCVAWVIVRSRLPQFTLRQGLDVGWCGTFGNVVTLGAGA
                     VPVQLYYLHRAGLPLGPGAGLMTLEYVFHKSTVLLYATVMLLLQHRWLAANTTGVMRYL
                     PMAYAVVAVIIVALVLLCVSPLVQNLARWLLGFLPKTEKWQQRRADWLEQLEVLGTESR
                     RLLTDKPRCLKIFALQALKLFGLFCLPYLCIRFMGLSPLGFWQVQLLTSLMLFVSNALP
                     NVAGMGSIETAFLLVFGSFLEQGEVMSVLMLYRIASYYVVFAASAAGFFIAQRHLAQME
                     PPKEG"
     CDS             complement(9383..10990)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MYTSYSTLQRKQLCKQVYTDTQSTYLLVYAPGRHKALQAALQNQL
                     HRKFRLVTRLEDELTPDVAGVLLVSEDVECTPTALTYFAAALREGADLAVCDASFGFDG
                     STALYLSTRHLPGSSCALVSRALLDKVRAAARGKDSVTELLRLAHAMAQHSRCIPQALL
                     HFRRELCADDVFSAKGRRALILSHELTMTGAPIVLVSAVPVLRSLGFEVVVLGPSDEGS
                     LPLFLDAGAAVVTRPDCVTSSALWGLATSADFVLANTVVEAPVVNTLNGSFVPVLWWLH
                     DAFAGYPFISHSIPKALGKNVHLCAVGSHATAAMHSVRPDFAIEQLIYGLPDYAAEQFS
                     RYDISFAGGRPLFVTVGSLEHRKGPDIFCNAIRLLPSAVREKAAFLFVGKAADKGMYNA
                     VDSLVRDYPQTVFYRKRLERPEVKSLMEQCNCVVCASRDDPMPTFVTEGLIFGKPSIVS
                     EHTGTAGLVTEGVDGFPYKDDDPQQLADKLAWAIEHPEALAAMHGSCRRLYEQQFSNES
                     YVATLTRLVKELTDGEES"
     CDS             complement(11025..11819)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MNHDAPMTPAAMQAHIAELEQQLKLSDEGVSQLAQRCLELEQQLL
                     ACQTELAKHSAEAENITLTLPQLFYDTGSGFSPRECLTATEDVYNELTHEVSVTFVLPE
                     DARAIRLDPGELACCITDLAISDERISFQSVNGLLLQEDSLLFLDVDPNLSLHCTTGFG
                     AGMKFAVNYHYYPLGRFLHEQPGKSLLRALNDLKLENAAAAQEAEEVLQASRAECMRLN
                     QQLLTLQGIQHEYQVSLETMRASSSWRLTAPLRRLLNLVRGH"
     CDS             complement(11886..13001)
                     /locus_tag="ctg4_9"
                     /transl_table=11
                     /translation="METTKPRTVNSIGMFDMLKGAGMLAIVLGHTAELYPLQLEGGLSL
                     TAFVGFIYRETLMAAFFIASGYGFRKRSISKCIHQQLKSLLKPFCYTAVFTTVLHFIIH
                     YKTFHYLPGSMTESIKVAGGFLLGLPHTATYFGQEFFSCGPMWYLLALLMGWILLDVIL
                     NIFPERYIPWAVGGAALLGWGASLVWELPFCLIQGAVITPYLYLGYLAKRQHWLDQPLS
                     RRMSCILWAAVLLIPAAALATRRTDCVSMAEWSLGPISILLDGLAGLLFIRLFLRWSQR
                     RNPLVRFFEAIGRRSLYIFCVHTVELIAIPWYLFAAKYADRPVLGISLQYILSLGSIWL
                     ICALLQRRRDLIIKLFPARRRTPQVHYAPRH"
     CDS             13378..14847
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 211.9; E-value:
                     4.1e-65)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_10"
                     /sec_met_domain="AMP-binding (E-value: 8.2e-65, bitscore:
                     211.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKVLDNVYDLVTLNMEQRFSERVALRFYDKETDEVTAVHYKDYA
                     RDIRRAVSYFQSTIPDIKGKKICLLNKNCYEYAVNTFGIILAGGVLVLLNQHKSWDELS
                     YELGLVDPAAILTDGDDYGTKEQLQAAYGSILRPMDGFRAYEPVAEMPRCIGHDDLMIL
                     MFTSGTTGRSKGVMLSERNFFSVMRAHVQIGERMMEYKHDPELVVSQYTVLPMFHLGAF
                     ICLFSWAHGGWALNISGDIRNFYKEIRRMPSQVMAVVPVIMNSLHKDVMRGRKERLGEL
                     WVPICSSAMFDPQVMLDMATNGMFVVQTYGATETCGDGIINYAQDAKHIGAVGQGNDYL
                     DYKLEPDGELCIRGDSIMLGYYKDPEATAAVIDKDGWFHTGDLARVDEDGYYYITGRKK
                     NLIILDSGENVSPEELEGMLEKCPAVQECIVKELGKKIGVVVYCEKEHQQTVRDFIAQM
                     NRTVPLYKRIGVVEFSETPLPRNGAGKLVRK"
     CDS             14875..15117
                     /locus_tag="ctg4_11"
                     /transl_table=11
                     /translation="MERAEIISQITAILEDVAEVSPEDVTESSVLMDDLDLSSMEILTI
                     VADLEETFGLRIPEKELRNFVTMGDLVDYLAANVG"
     CDS             15169..16332
                     /locus_tag="ctg4_12"
                     /transl_table=11
                     /translation="MYFFRREKIQCRYQFSLRDAVDITLLQRALTAALASAPYYTQRLV
                     QEKREMWLEPNTEPCLVYPGSTMRNIPEQTNGYLFCVSCEGDTVYFDWHHFLLDGHGVS
                     PLLTSILEQYCNLRYGTAFAVPQIVCDPPYDMEAMLAEYPPVEYGSDVIQRDVVQTYEG
                     ALRRTRVCLSKQSLVEKALANNAKPVSALMGLLCMAMREYLGKEKIQYSYSSDTRDVAG
                     VPNALYNCVCSFGHTVQLQAQTRLADFVSDVDADIKRDLQPESKRHRMADQMGWVYKVN
                     QQKAPLRIKQRVFQMGEYIGGTISDFWLSYLGNPLMPATPELAQYTTDFGVWVPPDGAS
                     VGVEAASLNGKIILCIHNKAPNPGLADILRKTFENEGVAVLEAEDLD"
ORIGIN
        1 gggctacacc ggaaaaaact gaagattcac gcctgttcgg cgtgaagatc ttttaaccgt
       61 tttttccggc tccgccgatt tgcagcccct cagtcgctgc gcgacagctc cccccgggga
      121 gcaagcgcag cagctgccgt ttcccgccac gacccctccc gtgaaaatag cgtttggagc
      181 gctccgcaga gcgcgacaaa cgcgaaattt aaaatatttt ttccgctgaa gatggctaga
      241 gcgaagcgga agccatttaa aatcgtctca gcgccccaaa cagcccacct ttacccgctt
      301 ttgcaaaaaa ttgcattttc cgcaaatttg tgcttgacaa cagaccgact ttccgatata
      361 atagagcacg ttcccgcggt aagatgccgc acgaacttga gcgatcatgg cccggtagct
      421 cagttggtta gagcaccagc ctgtcacgct gggggtcgtc ggttcgagcc cgatccgggt
      481 cgccatttgc tgctatagct cagttggtag agcgcatcct tggtaaggat gaggtctcca
      541 gttcgaatct ggatagcagc tccaaaggca agcacctcga agtcttagga cttcggggtg
      601 tttttttgcg cttttttcag ggcaggagga ctgttgcatc ctactgcttg tggaaaccgc
      661 ccaaaataga acgacttttt ctcccggtac gtcaattgaa gctgcctcca aattgttata
      721 taattaacat aataatgaaa tatggcacag tgctgcgtgt gccgtactat ttttggaggt
      781 tttgtattat ggctcgtttt actctgcccc gtgatctgta ccatggcaag ggcgctctgg
      841 aagcgctgaa atccttcacc ggaaaaaagg caatgatctg tgtcggcggc ggctccatga
      901 agcgcttcgg cttcctggac cgtgctgtgg agtacctgaa ggaagccggc atggaagtgg
      961 agctgttcga gggcatcgaa cccgatcctt ccgtggagac cgtcatgcgc ggtgccgagg
     1021 ccatgctgaa gtttgagccc gactggatca tcgccatggg cggcggctct cccatcgatg
     1081 cagccaaggc catgtggatc aagtacgagt accccgagat cacctttgag gagatgtgca
     1141 aggtgttcgg catcccgccg ctgcgccgca aggcacactt ctgtgctatt tcctccacct
     1201 ctggcactgc caccgaggtg accgctttct ccatcattac cgactaccag aagggcatca
     1261 agtaccccat cgcggacttc gagatcaccc cggacgtggc catcgttgac cccgatctgg
     1321 ctgagaccat gcccaaaaag ctggttgccc acaccggtat ggacgccatg actcacgctg
     1381 tggaggctta tgtttccacc gcgcactgcg actacaccga cccgctggcc atcttcgcca
     1441 tccgcatgat ccagggcgat ctggtggaca gctacaatgg cgatatgtcc aagcgcgact
     1501 ccatgcacaa cgcccagtgc cttgccggta tggctttctc caacgcactg ttgggcatcg
     1561 tgcactccat ggcccacaag accggcgctg cctttgcaga ctacggcgca cacatcatcc
     1621 acggcgcggc caacgccatg tacctgccta aggtcatcgc cttcaacgcc aaggaccccg
     1681 aggccaaaaa gcgctacggc gtcatcgcag acgagatgaa gctgggcggc gcaaacgatg
     1741 acgaaaaggt caagctgctc atcgagtacc tgcgcggcat gaacgacgcg ctgaacatcc
     1801 cccactgcat ccagcactac ggcccggact cctaccccac cgagcagggc tttgtgccgg
     1861 agaatgtgtt cctggagcgg ctgcccgaga tcgccaagaa cgccatcgcc gacgcctgca
     1921 ccggctccaa cccccgccag cccagtcagg aggagatgga gaagctgctc aagtgctgct
     1981 actacgatac tgaggtggat ttctgatccg tcctttcttt attacgcctc cttccctatg
     2041 gacaaaagcc ccgcagagca taccgccctg cggggctttt gccggtttcg cctgcattct
     2101 cccgtgaaaa aaggggttcg gaaacgccta cggcgtttcc gaaccccttt catactacta
     2161 aggcgttaca gcttgctcag ctggggaccc tgtgcggtgt ccttgacagc ccagcccagt
     2221 tcggtcagct gtgcgcggat ggcatcagcg gtggcccagt ccttggcctt cttggcagca
     2281 gcacgcttct ccaccagcgc ggtcacctcg gcgggcactt cgtccttctt gcggttgtac
     2341 agcagaccca gcacgccggt gatctcgtca aaggcggcgg cagcggtctc cagtgcagcc
     2401 ttgctggaag cagcagacag ggtgttgatc tccttgacca gatcaaacac ggcagcaagc
     2461 gcatccgggg tgttcaggtc gtcgtccatg gcggtgcaga acttggtgcg tgcctcggcg
     2521 gccttttcct tcagggtctc gtcggtgccg aagtcggtct tgctcagggc aaagtccaga
     2581 ttctcgcggc aggtgtacag gcgctccaga ctgttcttgc agctctcgat gaggtctacg
     2641 gtgtagttca ggggcatgcg gtagccggcg gtcagcatga agtagcggat gggctcgtag
     2701 ccgtagaggt ttgccacatc ccgcacggta aagaagttgt gcaggctctt ggacatcttc
     2761 tgattgtcca cgttgatgaa accgttgtgc atccagtagc gggcaaactc gcagccgttg
     2821 gcgcactcgc tctgggcgat ctcgttttcg tggtggggga agatcagatc ctgaccgccg
     2881 cagtgcaggt cgatggtctt gcccagatgg gtgcggctca tggcgctgca ctcaatgtgc
     2941 cagcccgggc ggcccatgcc gtaggggctt tcccatgcgg gctcaccggg ctttgcagcc
     3001 ttccagacgg caaagtcggc gggatcctcc ttcagatcgt cctccatacg gctgcgcagc
     3061 tcgcggttgc cgctctccag atcgtccaga ttcaggtggc tcagcttgcc gtagccgggg
     3121 tcgctcttca cccggaagta cacatcgccg ttcttggcaa cataggcgtg gccagagtcg
     3181 atcagatctt tgacgatatc caaaatctgg gggatatgct cggtagcgcg gggctgcacg
     3241 gtgggctttt cgcagttcag accggcggca tccttcaggt actcggcctc aaagcgctgt
     3301 gccacctcct tcatggaggt gccctcttcc tgccccttct tgatgagctt atcgtcgata
     3361 tcggtgatgt tggaaacgta gatcaccttg ttgccccggt attccagata gcggcgcaga
     3421 gtgtcgaaca cgatcagcgg acgtgcgttg ccgatgtgga tatagttgta cacggtaggg
     3481 ccgcagacgt agatgcggta ctcgccgggc acctgcggca caaattcttc cttctgtcgg
     3541 gtcagggtgt tgaagatctg catggtcaat tctccttttt gttccaaaca gaagccgcaa
     3601 aacaaaacgc ccccggagcg gtgcacaagg cacaactccg aaggcggttt taaaatcaaa
     3661 atcgcggttc cacttctgtt tgtcgctcaa agccggtaac ggcggcgtac cgcacggcga
     3721 tacttcccca cggggttccc gccgcgtgct gtccgggcgc actttgcgca gcggtctgca
     3781 aacaggcttc cagccagtgg cctgttctct ctgcgcagac ggtgtgcggc gctactctgc
     3841 ccggataaac gcatttatcc ttttacccct ttattatagc ggtgcggtgc agggaagtca
     3901 aggagggaac aaagaacgat tcagaatgcc cgccgcgttg ctctgggcat cctcagcgga
     3961 agaattattt taaatttcgg gatatcggaa cgcctgcggg cgttccgata tcccattttt
     4021 acccgtgaaa agggcccccg gagcgtccgc agacgctccg ggggccaaaa tcatagatat
     4081 tctttccgct gaaattgcgc agagcgaagc ggagcgcaat caaaacggtg gtgctttacc
     4141 cgggatagcg gctcacttcc agcagttctt ctgcccgctt tacctgctct gccgtgggcg
     4201 gtactgcgtc cggcagggga taggggatgc ccagcttctg ccacttgaac agccccaagg
     4261 tgtggtaggg cagcacctcc acccgctgca ccgttttcag gctgcggata aagtctgctg
     4321 ttttgcgcag cccttcctcg tcatcggtca gcccgggcac gaggacgtgc cggatccaca
     4381 gcgggatgcc gaggtcggag atgtgccgcg ccatggcaag gatgttggcg ttgtccttgc
     4441 cggtgagctg ccggtggcgc tccgggtcga tctccttgag gtcaaggatc accagattgg
     4501 tgttagccat caggcggtcg aacgcggcca gataggccgg gtcgtccggg cggaagggct
     4561 gcccggcggt gtccagcgcc gtgtgcacgc ccttggcacg cgccagcgtg aagaactcgg
     4621 tcagaaagtc cagctgccgc agcggctcgc cgccgctgac cgtgatgccg ccctttttgc
     4681 cccagtagtt gcggtagcgg tatacccgct ggaacagcgc ttctgccgtc cacgcctcgc
     4741 cgccctctgc ccatgtttcg gggttgtggc agtacttgca ccgcagggca cacccctgca
     4801 aaaacaccac aaagcgcacg ccggggccgt ccaccgagcc gaaggattcc agcgagtgga
     4861 cgtacccaag ggtcttacag gacgccatgg caggtgcgtg ccagcacgtc cagctgctgc
     4921 tcgcgggtca ggtcgatgaa cttgacagcg tagccggaaa cgcggatggt gaagttggcg
     4981 tactcttcct tctcagggtg ctccatggcg tccagcagct tctccttgcc aaagacattc
     5041 acgttcaggt ggtgtgcgcc ctgatcgaag tagccatcca gtacctgcac cagattctcc
     5101 acgcgctcgt cctcgctgtg acccagtgcc tcggggttga tggtctgggt gttggagatg
     5161 ccgtccagcg cccagtggta gggcagcttt gccacggagt tcagcgaggc cagcagaccg
     5221 ttctgctctg caccgtagct gggggtagcg ccgggggcaa acggggtgaa ggcggcgcgg
     5281 ccatccggca gagcgccggt gtacttgccg tacaccacgt tggaggtgat ggtcaggatg
     5341 gaggtggtag cctcggagtt gcggtaggtg tggcgcttct tgatcatctc aaggaaggtc
     5401 ttgagcagcc acacgccgat ctcgtcggcg cggtcgtcat cgttgccgta cttggggaag
     5461 tcgccctcgg tctcaaagcc ggtggcaagg ccgctctcgt cgcgcaccac cttcaccttg
     5521 gcgtacttga tggcgctcag ggagtcgatg acgtgggaga agcctgcaat gccggtggca
     5581 aaggtgcggc gcacatcggt gtcgatgagt gccatctcgg cttcctcgta gtagtacttg
     5641 tcgtgcatat actggatgag gttcagcacg ttgacataca gcccggccag ccagtccagc
     5701 atctgcacat acttgggcag cacctcgtca taggtcaggt actcgctggt gataggggca
     5761 tagttggggc cgcactgctc gtggctcttc tcatccacgc cgccgttgat ggcgtacagc
     5821 aggcacttgg caaggttggc gcgtgcgccg aagaactgca tctccttgcc ggtctgggta
     5881 gcagacacgc agcagcagat ggagtaatcg tcgccccaga cgggcttcat gacgtcgtcg
     5941 ttctcgtact ggacggagct ggtgttgatg gacaccttgg cggcgtactt cttgaagttc
     6001 tcaggcagag cagaggagta cagaacggtc aggttcggct ccggtgcagg acccatgttc
     6061 tcgagggtat gcaggaagcg gtagcagttc ttggtgacca tgctgcggcc gtccatgccg
     6121 atgccgccca cttccagcgt tgcccagacg gggtcgccgg agaacagctg gttgtagctg
     6181 gggatgcggg cgaacttgac catgcggaac ttcatgacca tgtggtcgat gagctcctga
     6241 gcctcgctct cggtcaggat gcccttgtcc agatcgcgct ggatataaat atcgaggaag
     6301 gtggagatgc ggcccacgct catggcggcg ccgttctggg tcttgatggc ggccagatag
     6361 ccgaagtaca gccactggca ggcctccttg gcgtccttgg caggctggga gatgtcgtag
     6421 ccgtaggcct cggccatctt cttcatgccc ttcagggcgc tgatctggcg ggcaatctcc
     6481 tcgcgcagac ggatgacgtc atcggtcatg gtgccgtcgc cgcagttggc aagatcctcc
     6541 tgcttgaact ggatcagggc gtcaatgccg tacagggcaa cgcggcggta gtcgcccacg
     6601 atgcggccgc ggccgtaggt gtccggcaga ccggtgatga tgtgggtgtg gcgtgccttc
     6661 ttcatctcgg gggtgtaggc atcgaacaca gcctgattgt gggtgcgggt gtagtcggta
     6721 aagatcttgt gcagctcggc agagggctgg tagccgtagg tggtgcaggc ctgctctgcc
     6781 atcttgatgc cgccgtaggg cataaaggcg cgcttgaggg gcttgtcggt ctgtaagcca
     6841 acgatctgct ccagatcctt caggttttcg tcaatatagc cggggccgta ggaggtcagg
     6901 ctgctgacca cctcggtctc catatccagc acgccgccct tggcgcgctc ggccttctgc
     6961 agctgctgca aagcacccca aagcttatcg gtagcctcgg tggggcctgc cagaaagctt
     7021 tcgtcgccgt catagggggt gtagttcttc tggatgaagt cacgcacatt gacctcttcc
     7081 ttccagatgc ggccttcaaa gccttcccac tgttcaaact ggatcattgg aacctccttg
     7141 ctccattacg cagttagcgt tttctaacta atgagccttt gaaaaaacgc tctgtctggg
     7201 cggttttctg ggggcgaaac ggtcttgcgc tgccgacagc ggcagccctt actacaaggt
     7261 gtagacaaaa ataaaaatct gcccacaaaa tcttgcgtta ttataatagc aagaatcgtt
     7321 ttaaaaagca atagaaaaca agtgggtttt cttccagcgg aaaggctgtt ctttgggcag
     7381 aatgtagaaa aacgccgaaa ccccggcggc acggcaactt tgcgaaaaaa tttgcaaatt
     7441 aagggttgac aagactaact gactgtggta tcctgttctc gcagcggcgg ttagctaatt
     7501 ctaaccacgt tgcaccagaa aaaggagcgt ctgcaagcgc tccgctccat tcctccattc
     7561 ctttctcttt tctacgggaa gcggcagcac ggtttgctct gctgcttccg gcgcggcacc
     7621 ggctgtgttt ggtaccacag ccgacgcaaa gaaaacaaaa acgggacgtg cagcttgacc
     7681 aactgcacgc cccgtttttt gtttttactg ccccatcccc gccagctgtt catacagctg
     7741 cgctgcgccg ccgccggggt attttacgct gacaaaggcg ctgttcagga tgcacacgcc
     7801 gtcagaatac accgtcagca gaaacttctg gttctcggca tcgtcataaa agctgacggt
     7861 gaccgactgc accgggaagg tatcgtgggt gtaggcagaa tagttctggt tcagcttttt
     7921 gcggcaggag acggtggaaa gcaattctgc cgtttgttgg aactcttcgc tgtccatgga
     7981 gaggaggtga tagtccatgt cgtttgtgct gccaaaatgc gccacttcct cggtgcggag
     8041 cgtgccctgc gagctggcgc gcaccagcgc tttcaggtcg atgggacggt acagcaccgc
     8101 aaaagctgcc agtgcaaaca ggataaaaaa taaagcggtg cggggaatgt ggaagctttt
     8161 catctgctca cccctccttt ggcggctcca tttgcgccag atgccgctgg gcgatgaaaa
     8221 agcccgcggc gctggcggca aataccacat aatagctggc gatgcggtag agcatcagca
     8281 cgctcatcac ctcgccctgc tccagaaagc tgccgaacac cagcagaaag gcggtttcga
     8341 tcgagcccat cccggctaca ttgggcaggg cattggagac gaagagcatc aggctggtga
     8401 gcagctgcac ctgccagaag cccagcgggg aaagccccat gaaccggatg cacaggtagg
     8461 gcaggcagaa cagcccgaac agcttgagtg cctgcagggc aaaaattttc aggcagcggg
     8521 gcttatctgt cagcaggcgg cggctctcgg tgcccagcac ctccagctgt tccagccagt
     8581 cggcgcggcg ctgctgccac ttttcggtct tgggcaaaaa gcccagcagc cagcgggcga
     8641 ggttctgcac cagcggcgag acgcacagca gcaccagcgc cacaataatt accgctacca
     8701 cagcgtatgc catgggcaga taccgcatga caccggtggt gttggcggca agccagcggt
     8761 gctgcaacag cagcatcacg gtggcgtaca ggagcaccgt gctcttgtgg aaaacgtatt
     8821 ccagcgtcat cagccctgcg ccggggccaa gcggcagccc ggcccggtgc aggtagtaca
     8881 gctgcaccgg aacagcaccg gcacccagcg tgaccacgtt gccaaaggtg ccgcaccagc
     8941 ccacatccag cccctgccgc agggtgaact gcggcagacg gctgcgcacg atgacccacg
     9001 ccacgcaccc ctccagcagg gggtagctga tgccgaccgc cagcaccgcc agcacctgcc
     9061 acaccgaaag ctgcgccagc gccgcagtga tctcggccca gtgatcctta aaagtgaaca
     9121 cgatgatgca ggtaagtgcc agcagcacca gcagagagat cacggccttt ttgcgggagg
     9181 gctgctgcgc ggcggcttgg ctcatggaaa caaaactcct ttcacaaccg gaaattctgg
     9241 aaccagtata gcacatctcc cgccgccctt tgtgaacgga agcggaactt tgttgggcaa
     9301 tttgggggat ttgataaaat ggggagacct ctcccgtgaa aaagcaatgc cgggcagcgt
     9361 gcagctgtcc ggcagtgttt tttcatgatt cttccccgtc cgtcagctct tttaccagcc
     9421 ttgtcagggt ggcgacatag gattcgttgg agaactgctg ctcatacagg cggcggcagc
     9481 tgccgtgcat ggcagccagc gcctctgggt gctcgatggc ccaggccagc ttgtcggcca
     9541 gctgctgcgg gtcgtcgtcc ttgtagggga agccgtccac gccctcggtc accagcccgg
     9601 cggtgccggt gtgctccgat acgatggagg gcttgccgaa gatcagtccc tcggtgacga
     9661 aggtgggcat ggggtcatcc cgggaggcgc acaccacgca gttgcactgc tccatcaggg
     9721 atttgacctc cgggcgctcc agccgcttgc ggtagaaaac ggtctgggga tagtcccgca
     9781 ccaagctgtc cacggcgttg tacatcccct tgtcggcggc tttgcccaca aaaaggaagg
     9841 cagctttttc ccgcactgca gagggcagca gccggatggc gttgcagaag atgtccggac
     9901 ccttgcggtg ttccagcgag cctaccgtca caaagagggg acgccccccg gcaaagctga
     9961 tgtcatagcg ggagaattgc tcggctgcat agtccggcag accgtagatc agctgctcga
    10021 tggcaaaatc cggccggacg gagtgcatgg cggcggtggc gtgggagcct acggcgcaga
    10081 ggtgcacgtt tttgcccagc gccttgggga tgctgtggga gatgaagggg tagcccgcaa
    10141 aggcatcgtg cagccaccac agcaccggca caaaggagcc gttcagggtg ttcaccaccg
    10201 gcgcttccac caccgtgttg gccagcacaa agtctgcgct ggtggccagc ccccacaggg
    10261 cgctggaagt aacgcagtcc gggcgggtga ccacagcggc cccggcgtcc agaaacagcg
    10321 gcagcgagcc ttcatccgag ggtcccagca ccaccacctc aaagcctaag ctgcgcagca
    10381 ccggcacggc acttaccagc acgatgggcg caccggtcat ggtcagctca tggctcaaaa
    10441 tcagcgcacg gcggcccttg gcagagaata catcgtcggc gcacagctcc cggcggaagt
    10501 gcagcagcgc ctgcgggatg cagcggctgt gctgcgccat ggcgtgggcc agacgcagca
    10561 gttcggtaac gctgtccttg ccccgggcgg cggcgcgtac cttgtccagc aatgcgcggg
    10621 acaccagtgc gcagctgctg ccgggcaggt gccgggtgct caggtacagg gcggtggagc
    10681 cgtcaaagcc aaaggaggcg tcgcagaccg caaggtctgc gccctcccgc agggcggcgg
    10741 caaaataagt cagggcggtg ggggtgcact ccacatcctc gcttaccagc agcaccccgg
    10801 ctacatcggg ggtcagctcg tcctcaagcc gggtcaccag acggaacttg cggtgcagct
    10861 ggttttgcag cgccgcttgc agcgccttgt gacgccccgg cgcgtagacc agaagatagg
    10921 tgctctgggt atcggtatag acctgcttgc acaattgctt gcgctgcagg gtactgtaac
    10981 tggtgtacat gatccaactc ctccgggcag aatatcgggc gggctcagtg accgcgcact
    11041 aggttcagca gtctgcgcag cggggcggtc agccgccagc tgctgctggc gcgcatcgtt
    11101 tccagcgaaa cctgatattc gtgctggatg ccctgcaagg tcagcagctg ctggttcagc
    11161 cgcatacact cggcgcggct ggcctgcaat acttcctctg cctcctgcgc ggcagcggcg
    11221 ttctcaagct tcaggtcgtt cagcgcccgc agcagagact tgccgggctg ctcgtgcaga
    11281 aaacgtccca gcgggtagta gtgatagttc accgcaaact tcatgccggc accaaagccg
    11341 gtggtgcagt gcagcgaaag gttggggtct acgtccaaaa acagcaggct gtcctcctgc
    11401 agcagaaggc cgttgaccga ctggaagctg atgcgctcgt ccgagatggc aaggtcggtg
    11461 atgcagcagg ccagctcgcc ggggtccagc cggatggcgc gtgcgtcctc cggcaggaca
    11521 aaggtgaccg agacctcgtg ggtcagttcg ttgtagacat cctcggtggc agtcaggcat
    11581 tcccggggcg aaaagccgct gccggtgtcg tagaacagct gcggcagggt aagggtgata
    11641 ttctcagcct cggcgctgtg cttggcaagc tcggtctggc aagccagcag ctgctgctcc
    11701 agctccagac accgctgcgc cagctgggaa acaccctcgt ccgaaagctt gagctgctgc
    11761 tccagctcgg caatgtgcgc ctgcatggca gcaggggtca tgggggcatc gtggttcata
    11821 acgggatcct cctcttcctt tatcctataa cagctgcacc gccgcagcca aaacattcag
    11881 aaaaatcagt gccgcggggc gtaatgtacc tgaggggtgc gccgccgggc ggggaacaac
    11941 ttgatgatca gatcccgccg ccgctgcagc agggcgcaga tcagccagat ggagcccagc
    12001 gaaaggatgt attgcaggct gatgcccaaa acagggcggt cggcgtattt ggcggcgaac
    12061 agataccacg gaatggcgat cagctccacc gtatgtacgc agaagatgta cagagaacgg
    12121 cggccaatgg cctcgaaaaa gcgcaccagc gggttgcggc gctggctcca gcgcaaaaac
    12181 agccggataa acagcagacc ggcaaggccg tccagcagga tgctgatggg gcccagcgac
    12241 cactcggcca tggatacaca gtcggtgcgg cgggtggcaa gggcggctgc cgggatcagc
    12301 agtacggctg cccacaggat gcaggacatc cggcgggaca aaggctgatc cagccaatgc
    12361 tgccgtttgg caaggtagcc aaggtacagg tacggcgtga tcaccgcgcc ctggatcagg
    12421 cagaagggca gctcccatac aaggctggca ccccagccca gcagggcggc accgcccacc
    12481 gcccaaggga tgtaccgctc cgggaagatg ttcaggataa cgtccagtaa gatccagccc
    12541 atcaacagcg ccagcagata ccacatgggc ccacaggaaa agaactcctg cccgaagtag
    12601 gtggcagtat ggggcagacc cagcagaaag ccgcccgcca ccttgatgct ctcagtcatg
    12661 gagccgggca gatagtgaaa ggttttataa tgaatgatga agtgcagcac cgtggtgaac
    12721 accgcagtgt agcaaaaggg cttgagcagg cttttgagct gctggtggat gcacttgctg
    12781 atggagcgct tgcggaagcc gtagccgctg gcaataaaaa aggccgccat cagcgtttcg
    12841 cggtagataa agccgacaaa ggccgtcagc gacaggccgc cctccagctg gagtgggtaa
    12901 agctccgcag tgtgtcccag cacgatggcc agcatcccag cgcccttgag catatcaaac
    12961 atcccgatgg agttgacagt gcggggcttg gttgtttcca tgaaagattc cttccctgcg
    13021 ccgggccaat accccctcga gaaaaaagcc ggatacggcg caaatgatca gtttttatac
    13081 agcattgcca tgatatatgg ctagtataat gctttttata gagactgtca attttgtttt
    13141 gcagtctgca ccataccgga actggtattt tgcgctaaaa attgtagcac gaaaaccggc
    13201 ggattgcaac gaaaggtaga atttggccgg ggcgtatccc aagatatgca attgaaagtt
    13261 gtcaaagtga gaaattaaat gttgcagaag tattgcattg cattggaaaa tattgtatac
    13321 tgagcacagt acagcgcact gccgcaggat gaaataacaa cgcaggagga aaatacaatg
    13381 atcaaggtat tggacaacgt gtatgatctg gtcaccctga atatggaaca gcgtttttcg
    13441 gagcgtgtgg cgctccgctt ttatgataag gaaacggacg aggtgaccgc agtccattat
    13501 aaggactacg cgcgggacat ccgccgtgcg gtcagctact tccagagcac catcccggat
    13561 atcaagggca aaaagatctg tctgctgaac aagaactgct acgagtatgc cgtgaacacc
    13621 ttcggcatca ttctggcggg cggcgtgctg gtactgctca accagcataa gagctgggac
    13681 gagctgtcct acgagctggg gctggtggac cccgctgcca tcctgaccga cggcgacgac
    13741 tacggcacaa aagagcagct gcaggccgcc tacggcagca ttctgcgccc catggacggc
    13801 ttccgcgctt atgagccggt ggcagagatg ccccgctgca tcggccacga tgacctgatg
    13861 atcctgatgt tcacctccgg caccaccgga cgcagcaagg gcgtgatgct gagcgagcgc
    13921 aacttcttca gcgtgatgcg cgcccatgtg cagatcggtg agcgcatgat ggagtataag
    13981 cacgacccgg agcttgtggt cagccagtac acggtgctgc ccatgttcca tctgggcgca
    14041 ttcatctgcc tgttctcctg ggcacacggg ggctgggcgc tgaacatcag cggcgatatc
    14101 cgcaacttct ataaggagat ccggcggatg cccagtcagg tcatggcggt ggtgccggtg
    14161 atcatgaact ccctgcacaa ggacgtgatg cgcggccgca aggagcgctt gggcgagctg
    14221 tgggtgccca tctgctcctc tgcgatgttt gacccgcagg tgatgctgga tatggccacc
    14281 aacgggatgt tcgtggtgca gacctacggc gctaccgaga cctgcggcga tggcatcatc
    14341 aactacgcgc aggatgcaaa gcacatcggc gctgtgggac agggcaacga ttatctggac
    14401 tacaagctcg agccggacgg agagctgtgc atccggggcg acagcatcat gctgggctac
    14461 tacaaggacc ccgaggccac cgctgcggtc atcgacaagg acggctggtt ccacaccggc
    14521 gaccttgccc gggtggacga ggacggctac tactacatta ccggccgcaa gaagaacctg
    14581 atcattctgg acagcggcga gaacgtcagc cccgaagagc tggagggcat gttagaaaaa
    14641 tgtcctgccg tacaggaatg tatcgtaaaa gaactgggca aaaagatagg tgttgtggta
    14701 tactgtgaaa aggagcacca gcagacggtg cgggacttta ttgcccagat gaaccgcacc
    14761 gtcccgctgt acaagcgcat tggcgtggtg gaattcagcg aaacgccgct gccccgcaac
    14821 ggcgcaggca agctggtgcg caagtaaaac gcaacagaaa ggaagcataa tacgatggaa
    14881 cgtgcagaaa tcatttctca gatcacggct attctggagg atgtcgcaga ggtatcgccg
    14941 gaggatgtga ccgaaagcag cgtcctgatg gacgatctgg atctgtcctc tatggagatc
    15001 ctgaccattg tggcagatct tgaggagacc tttggcctgc gcatcccgga aaaggagctg
    15061 cgcaactttg tcaccatggg tgatctggtg gattatctgg cagcaaacgt ggggtaaaaa
    15121 ccaatggaaa cacagcagcg ctcgacggaa tataactttc agggaatcat gtactttttc
    15181 cgtcgggaaa agatccagtg ccggtaccag ttctcgctgc gggatgcggt ggatatcacc
    15241 cttttgcagc gggcactgac agcggccttg gcaagtgcgc cttattatac gcagcgtctg
    15301 gtgcaggaaa agcgggagat gtggctggag cccaatacgg agccctgcct tgtgtacccc
    15361 ggcagcacca tgcgcaatat cccggaacag acgaacggct acctgttctg cgtcagctgc
    15421 gaaggggata ccgtctactt tgactggcat cacttcctgc tggacggcca cggggtatcg
    15481 cccctgctca ccagcattct ggagcagtac tgcaacctgc gttacggcac ggcctttgcg
    15541 gtgccgcaga tcgtgtgcga cccgccctat gatatggagg ccatgctggc agagtacccg
    15601 cctgtggagt acgggagcga tgtcatccag cgggatgtgg tgcagaccta cgagggtgcg
    15661 ctgcgccgca cccgggtgtg cctgagcaag cagagccttg tggaaaaagc gctggcgaac
    15721 aacgcaaagc cggtaagcgc tctgatgggt ctgctgtgta tggccatgcg ggagtatctg
    15781 ggcaaggaga agatccagta ttcctactcc tccgataccc gcgatgtggc cggtgtgccg
    15841 aatgcgctgt acaactgcgt atgcagcttt gggcatacgg tgcagctgca agcccagacc
    15901 cgcctggcag attttgtatc tgatgtagat gcagacatca agcgggacct gcagccggag
    15961 tccaagcgtc accgtatggc cgaccagatg ggctgggtgt acaaggtgaa ccagcaaaag
    16021 gcacccctgc gcatcaagca gcgggtgttc cagatgggcg agtacatcgg cggcactatt
    16081 tcggatttct ggctcagcta tctgggcaat ccgctcatgc ccgccactcc ggaactggca
    16141 cagtacacca cggattttgg cgtctgggtg ccgccggacg gtgcatccgt gggcgtggag
    16201 gctgccagcc tgaacggtaa gatcattctg tgcatccaca acaaggcacc caacccgggt
    16261 ctggctgata tcctccgcaa gacctttgaa aacgaaggcg ttgcggtgct ggaagccgaa
    16321 gatctggact gagaaatact tatcataaaa gaaaaaactg ctgcacgttt tgtgcggcag
    16381 tttttttgct gctttttgta agaaaatccg gttgcaaaga tgcgaaaaaa tggttaaata
    16441 gagaaaggat atttccgcaa ggagaggaac accatggaac aacagaacac gcgcctgcgc
    16501 aatgcgggct ttgcgacctt tttcttcagc ggcatctgtg ccatcagcgc aggtgtggtg
    16561 gtcagtctgc tgcaggagcg ctacggcttt gcctacggca tgaccggtac actgctctcc
    16621 ctgatgagcg tgggcaacct gctggcaggg ctgctgatgg gcatgctgcc cagtgcgctg
    16681 ggcatgaaac gcagtgtgct gctgctgacc atcggctatg cggtgggcta cgccgtcatg
    16741 gggctgaccg gcgcagtggt gctgctggca gcggcctttt ttgtggtggg catcgctaag
    16801 ggcagcgtta tcaacacctg taccattctg gtcagcgatc actccgccga ccgcacccgg
    16861 ggcatgaacc tgatgcacag ctgctacgcc tgcggcgcac tgctgtgccc cttcctcatt
    16921 gcggcggcag cccgggtaag caccgagctg gcggtctttc tgctggcagc cgtgggcctt
    16981 gtgctctggc tggtgtacgt ctttaccccg ctgcgcggcg gcaagagtaa aagcagcgcc
    17041 gagaaggaag ccatcgactg gagctttctg cgctctgccc gcttctggct gctgaccggg
    17101 ctgctgttct tccagaacgc cgccgag
//
