LOCUS       c00059_gnlPro..        17097 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CCFJLGKF_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:23:46
            Original ID  :: gnl|Prokka|CCFJLGKF_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17097
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17097
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4126:7097]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4127..7097
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17097
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17097
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(249..1511)
                     /locus_tag="ctg59_1"
                     /transl_table=11
                     /translation="MQQLHIKLEVDSPLIQWVNAQADSIGARGHIGTHLDCYTTVPEKE
                     EYQIKGIVIDCTAGMPSMDSMAHIGSLKNKALILHTGNLEHNRYGTEEYFNKDTTLCKV
                     SLHTILSKKPLFIIIDSHGIAEKGKRHIEFDKICEANGCHVIENVDLSCIGNQKEVPLK
                     ILININHKSTGKPCELYSILESCFDNTSSHEDSLKAWEANADFWDESMGENSNEFQRLT
                     VRPIVNELLKATQGDYILDIACGNGNYSGYLAEQGIDVLAFDYSQRMVELARKRQARFN
                     DRIEFCVADVTKYEDMMSLKRNKPFTKAVSNMAIMDISDIDNLFRCVNKLLAENGYFVF
                     STQHPCFVTLTNKYMTKHNYYGEAIEGQPQKQCYYHRSLQDIFEICFRHGFIIDGFYEA
                     CFGNDRERPVVIIIRAKKHNL"
     CDS             1777..2337
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="MDAIQLLKNRRSVRKYKDQIVPRELIEEIVKLSQFAPSWSNYQVA
                     RYNIIDNRSLIEEIANNCVQGFVYNAKTLTRANGVVVLSYVTGKSGSLKDKVKPEDVVS
                     DNSGAWECFDAGIACLQFCLSAYAKGVATCVLGVINNDAIAQKIGLPENEKVAALIVYG
                     YEAGEHHEAPVRKDINEILRFVE"
     CDS             complement(2393..2983)
                     /locus_tag="ctg59_3"
                     /transl_table=11
                     /translation="MSLAKTLKGDIIAVDLFEEFLEKLKENSAKENTTANIKTLSASMD
                     KLPFEKEELDIIWSEGAVYNIGFKNGINYWKEFLKPGGILAVSELSWTTNCRPKGLEDF
                     WTGEYAEMDTIAGKIRVLEEAGYKVLGHFILSDDCWLDNYYNPLLNSHKAFMDKFGNNE
                     TAEMIVERDIQEADFYKKYKNYYSYGFYIAQKL"
     CDS             complement(3045..3140)
                     /locus_tag="ctg59_4"
                     /transl_table=11
                     /translation="MDEFELMMHLHRNNKRQGQVRRVHKPSDYTG"
     CDS             complement(3163..3618)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_5"
                     /sec_met_domain="Acetyltransf_1 (E-value: 1.9e-13,
                     bitscore: 41.8, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVFKKIREHKEYIQDAASWFQAKWDIPQEEYLKSMNESLLKETSI
                     PQWYIMLENDNSIIGGIGVIENDFHNRKDLTPNICALYVDEKYRRQGVAGYMLKQVCDD
                     MKLLGINRLYLVTEHTDFYEKYDWSFLCMVQEENESNMLRMYSKNLD"
     CDS             4127..6355
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="Gly_radical (E-value: 2.1e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLIEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             6369..7097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 73.7;
                     E-value: 6.1e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_7"
                     /sec_met_domain="Radical_SAM (E-value: 2.4e-30, bitscore:
                     97.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFKLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQGKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(7090..7539)
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(7753..8256)
                     /locus_tag="ctg59_9"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVLTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             complement(8608..9147)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="MACAHYDFHAHPFGTDKGDAGVIASLDDREDACQFFFAEVVDVYH
                     DVSQIFDEVHFGTPSSVAGGEGDCRQFFFLLIGSLFSLLCKDAAYFFDFFPVGKTADSG
                     HYFFFGHLCYCVVETLKYGEMFHFYFDYCLSMQRNFFAEMCKGTLYKMAISYYGSPKKC
                     MIVATCFGERRRLRAR"
     CDS             complement(9721..9951)
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MIRLAEIGVNQIFDCFDSAGISQLVDFYPDTVFHHLIQDAERLRF
                     LGVGTPSAIFHDMQHFIVACFVVLADILFYP"
     CDS             complement(10246..10623)
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="MKDESLVILFKPFIVRLREPVLVPRLIQQIFDLSIELRIIDGNKL
                     DGIRMKTKETPVACRVVKHFLIIAGSCKRGRMREVLRTACIWQTETDHFARYQIFECIQ
                     FPTAHPFKLVEIDQHGLRYFG"
     CDS             10639..10881
                     /locus_tag="ctg59_13"
                     /transl_table=11
                     /translation="MVLTHIRKPERFEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGK
                     VMTKHHFESKKGNNGRRYAVFIIDIEQVKSNRLYE"
     CDS             complement(10951..11256)
                     /locus_tag="ctg59_14"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(11237..11569)
                     /locus_tag="ctg59_15"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             11586..12002
                     /locus_tag="ctg59_16"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPTKVRGVREELKLFLFYFFISTFYIS
                     LKKIRMLEILSHSSHFLPFLSPKRRREIGKTQPSFFDFSPHFQINPPIEADFRKYLLSL
                     MCKRSKESDMGNLMRKLPIGIQTFEDIRRKNILL"
     CDS             complement(12159..12413)
                     /locus_tag="ctg59_17"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYISVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGDFK"
     CDS             complement(12431..12565)
                     /locus_tag="ctg59_18"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSEKLLELIDQKKELSSN"
     CDS             complement(12683..14041)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 152.2; E-value: 5.8e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg59_19"
                     /sec_met_domain="MFS_1 (E-value: 3.1e-47, bitscore: 152.2,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDSERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     RGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFWVDALAMVLFGLGIGVLICFLGGLMAVDIAPCNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINWFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(14057..14962)
                     /locus_tag="ctg59_20"
                     /transl_table=11
                     /translation="MIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRADWRYA
                     PENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTLDSIRT
                     LYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVDQIIMK
                     GSKPVADVKNDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVSDTCQV
                     PKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQTDRTAY
                     LLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 gcaagaacag acacctgaac cataagatga tcagggcttt gggattttaa agacaatgca
       61 gacaataaaa aggatatgac ctatcctttt tattataagt tcaatcaacg tatatttacg
      121 attagttgct tttgttatcc aatctactga ttttttattg tgaaataaca atttctataa
      181 aacgctgtta tcataaaaat gaatcttgaa tacagccggg catcggagtt ctgattattc
      241 gatgaacatt aaagattatg tttcttagcc cgtattataa taacgacagg tctttctcta
      301 tcatttccaa aacatgcctc atagaatccg tctataatga atccatgtct gaagcatatt
      361 tcaaaaatat cctgtaaaga gcgatgatag taacattgct tttgaggttg tccttcaatg
      421 gcttctccat aatagttatg ttttgtcata tatttatttg tcaatgttac aaagcatgga
      481 tgctgcgtag aaaacacaaa atatccattc tcagcaagca atttgtttac acaacggaac
      541 agattgtcta tatctgaaat atccattata gccatattgg acacagcctt tgtaaaaggc
      601 ttgtttcttt ttaaggacat catatcctca tatttggtta catcagctac gcagaattct
      661 atcctgtcat tgaaacgggc ttgtctcttc cgggctaact caaccattct ttgtgaataa
      721 tcaaatgcca aaacatctat accctgttca gccaaatatc ctgaataatt tccattacca
      781 caagcgatat ccaatatata atccccttgt gtggctttta acaattcatt tactattggg
      841 cgaacagtca atctctgaaa ctcattcgag ttctcaccca tagactcatc ccagaagtcc
      901 gcattggctt cccaagcttt taaactatcc tcgtgtgagg atgtgttatc aaagcaactt
      961 tcaagtattg aatacaattc acagggctta cccgttgatt tgtgattgat attgattaat
     1021 attttcaacg gaacttcctt ttgattgccg atgcatgata aatcaacatt ttctattaca
     1081 tggcagccat tagcttcaca aatcttgtca aattctatat gtctctttcc tttctccgct
     1141 ataccatgag agtcaatgat aataaaaagc ggtttcttac ttaaaattgt atgtaaggaa
     1201 actttacaaa gagtggtgtc tttattgaaa tattcctctg tcccatatcg gttatgttcc
     1261 aaattcccgg tatgtaatat taaagcctta tttttcaacg agccgatatg tgccatacta
     1321 tccattgatg gcataccagc cgtacaatct ataacaatcc ctttaatttg atactcttct
     1381 ttttctggaa cagtagtata acaatccaaa tgagtgccga tatgtcccct cgccccaata
     1441 ctgtcagctt gtgcgttgac ccactggatt agaggagaat caacttccaa ttttatatgt
     1501 aattgttgca tattatgttc gttttgtata gtatttttgt caatttcaac gatttgatta
     1561 ggagcaaaaa tacggaaaag tatgcaaaca agaattcata tctattggaa agatattgtt
     1621 tttaatttat tttgtttact ttgcaatcaa aaaataaaga atcacactta tggatatcgc
     1681 aagtgtaata taaagatttg aagaaatagg tgtgtgttcc acaatagacg gagtgtgtca
     1741 tttgttttag aaattaacag caaaaacagt atatatatgg atgcaattca attattaaaa
     1801 aacagaagaa gtgttcggaa atacaaagat cagattgttc cgagagaact tattgaggag
     1861 attgtcaaat taagtcagtt cgcaccttca tggtcaaatt atcaggtagc aagatacaac
     1921 atcatagaca ataggtctct gattgaagag atagccaaca attgtgttca agggtttgtg
     1981 tacaatgcaa aaacattaac cagagccaat ggcgtggttg tgttaagtta tgtaaccggt
     2041 aaaagcggat cactgaaaga taaggttaaa ccagaagatg tagtgtcaga caacagtggc
     2101 gcatgggaat gttttgacgc aggcattgct tgccttcaat tctgcctttc tgcatatgcc
     2161 aaaggagttg ccacgtgtgt tttaggagta atcaacaacg atgctattgc ccaaaaaata
     2221 ggactccctg agaatgaaaa ggtcgctgca ctgattgttt atggttacga ggctggagaa
     2281 catcatgaag ctcctgtaag gaaggatata aatgaaattc tacgttttgt cgaataaata
     2341 tattcatatt atgttttgcc tccagtcttt taacaactgg aggctttctt cattataatt
     2401 tctgggctat atagaaaccg taactataat aattcttgta ctttttatag aagtcggctt
     2461 cctgtatgtc tctttcaaca atcatctctg cggtttcgtt attaccaaat ttgtccataa
     2521 aggccttatg gctgtttaag agaggattgt aataattatc aagccagcag tcatctgaaa
     2581 gaataaagtg tccgagtacc ttgtatccgg cttcttccag aactctgatt tttcctgcta
     2641 ttgtatccat ttcggcatat tctccggtcc agaagtcttc cagtcctttc gggcgacagt
     2701 ttgttgtcca tgacaactct gaaacagcca gtatacctcc cggtttgaga aactctttcc
     2761 aatagttgat gccgttcttg aatccgatat tgtaaaccgc tccttccgac cagatgatgt
     2821 caagctcctc cttttcaaaa ggcagcttgt ccatagatgc agacagtgtc ttaatatttg
     2881 ctgttgtatt ctcctttgcg ctgttctctt tcagtttttc aagaaactct tcaaacagat
     2941 ccacggcaat gatatcacct ttcagcgttt tcgccaagga catagtttgc gcacctgttc
     3001 cacatccaat atcagctatc ctgtaagact tttctctatc tatcttagcc agtgtaatcg
     3061 ctaggtttgt ggactcgtcg tacctggcct tgtctcttgt tgttacgatg caaatgcatc
     3121 atcaattcaa attcgtccat acaaataaat taagttattg gtctaatcca ggtttttact
     3181 atacattctt aacatattgg actcgttttc ttcttgaacc atacataaaa aactccaatc
     3241 atatttttcg taaaaatcag tatgttctgt caccaaatat aatctgttta ttcccaataa
     3301 tttcatatca tcacatactt gctttagcat atatccggcg acaccttgtc tgcgatattt
     3361 ttcgtctaca tataaagcac aaatattggg agttaaatcc ttacggttat gaaaatcatt
     3421 ttcaattaca cctatacccc caataatact attatcattt tctaacatta tataccattg
     3481 tggtatactt gtttctttta gtagactctc attcatgctt ttcaaatact cctcttgggg
     3541 gatatcccat ttagcctgaa accaagaagc agcatcttgt atatattctt tatgttcccg
     3601 tattttttta aaaaccatac ttttaatttt tattataatt gttcgttgat attttttgag
     3661 gatatttcgt ctgtatcaag gtggttatca cgaaatatcc aataaaaggg atgttaccgg
     3721 atcccaattt cgtccgaatt gcatttttgg gtgtgaaaaa gggtgtaaat cttgcaaatg
     3781 cttgatttac accctttatt gcggagagac agggattcga accccgggta cctcgcggta
     3841 caacggtttt caagaccgcc gcaatcgacc actctgccac ctctccaaaa cttccttatc
     3901 agaagtgctt ttcgttaaaa gcggtgcaaa ggtacgaaga tattttaaac ttgcaagagt
     3961 tttcactaaa aatttaatct aatcttttcc taaggatagc aattaatagg tattttatgt
     4021 tgaaaagcat aaaatagagc atatttatgc tgattatatg aaaaatgatt gtaactttgt
     4081 gcgctctaaa gaataggata actacaacct ctaattttat cattttatgg aattaaacaa
     4141 gatctttaaa gacggtcttt ggagcagcga aatcaacgtc agagatttcg taagtcataa
     4201 catcactccg tattacggag atgcttcatt cctcgaagga cctacagaac gtaccaaagc
     4261 cgtatggaac cgctgcctcg aagcgttggc agaagaaaga gaaaacaacg gtgtccgctc
     4321 attagataat gttaccgtat caaccatcac ttcccacaag gccggatata tcgacaagga
     4381 aaacgaactg atcgtcggcc tgcagacaga cgaacttctg aaacgtgcca tcaagccttt
     4441 cggaggtatc aacgtagtca gcaaagcctg tcacgaaaac ggcgtggaag tggacgaccg
     4501 cgtaaaagat attttcactc actaccgcaa gacgcacaac gacggagtat tcgacgtata
     4561 tacggaagaa atccgttcct tccgttcgct gggattcctt accggacttc ccgacaacta
     4621 tgcacgcgga cgcatcatcg gtgactaccg ccgtatggct ctttacggca tcgaccgtct
     4681 gatcgaagca aagaaggaag atttgcacaa cctcaccggt ccgatgacag atgcccgtat
     4741 ccgtctgcgc gaagaagtgg cagaacagat caaggcactg aaagacatga aagtgatggg
     4801 cgaatactac ggtctcgacc tgagccgtcc cgcttacacg gcacaagaag ccgtacagtg
     4861 ggtatatatg gcttaccttg ccgccgtcaa agaacaagac ggtgccgcca tgtcactggg
     4921 taacgtttct tctttcctcg atatctatct ggaatatgaa ctgagcaaag gaaccatcac
     4981 cgaatcgttc gcgcaagagc tgatcgacca gtttgtcatc aaactgcgta tggtccgcca
     5041 cctgcgtatg caatcataca acgacatctt tgcaggcgac ccgacctggg taaccgaatc
     5101 tctgggcgga cgtctcaacg acggacgtac caaagtgaca aagacctcct tccgtttcct
     5161 gcagacattg tacaacctcg gcccttcacc ggaaccgaac ctgaccgtac tctggagccc
     5221 ggaacttccc gaaggattca aagaattctg tgcaaaggtt tctatcgaca cttcttctat
     5281 ccagtacgaa aacgacgacc tgatgcgtga agtacgtcag tccgacgact acggaatcgc
     5341 ctgctgcgta tcataccagg aaataggcaa gcagattcag ttcttcggtg cccgttgcaa
     5401 cctggccaaa gccctgttgc ttgccatcaa cggcggacgt tgcgagaata ccggtacagt
     5461 catggtgaag aacatccccg tactgaccag tgacacgctg aagttcgaag aagtaatgga
     5521 caactacaag aaagtactga tcgaaatcgc ccgcgtatac aacgaagcga tgaacatcat
     5581 ccactatatg cacgacaagt attattacga gaaagcccag atggctcttg tagatacgaa
     5641 cccgcgcata aaccttgctt acggtgtagc cggactttcc atcgcactcg attcactgtc
     5701 tgccatcaaa tatgcgaaag taactgcccg ccgcaacgat atcggtctga cagaaggctt
     5761 cgacatcgaa ggagaattcc cttgcttcgg taacgacaac gacaaggtag accaccttgg
     5821 cgtagacctg gtatacttct tcagcgaaga attgaagaaa ttgcctgttt acaagaatgc
     5881 ccgtcctacc ctctccttgc tgactatcac ttccaatgtg atgtacggca aaaagaccgg
     5941 tgctactccc gacggacgtg ccaaaggtgt tgccttcgct ccgggtgcca acccgatgca
     6001 cggacgcgac aagaatggtg cgatcgcttc tctgagctct gtagcgaaac ttcgttaccg
     6061 tgactcacag gacggtatca gcaacacctt ctctatcgtt ccgaaatcac tgggtgctac
     6121 ggacgaagac cgtatcgaga acctcgtaac gatgatggac ggttacttca ccaaaggtgc
     6181 ccaccacctg aacgtaaacg tactgaaccg tgatatgcta tacgatgcca tggagcatcc
     6241 ggagaactat ccgcagctga ccatccgcgt ttccggttat gccgtaaact tcgtgaagtt
     6301 gagccgcgaa caccaactgg aagttatcag ccgtagcttc cacgaacgta tgtaatctat
     6361 tactctatat gatgataaac gtacattcat acgaaagtat gggaacattc gacgggccgg
     6421 gcttacggct cgtcgttttt cttcaaggat gcaacttccg ctgcctctat tgcgccaatc
     6481 cggatacgat agcaggaaag ggaggcacgc ctaccccacc ggaagaaatc gtccgcatgg
     6541 caatgagcca gcgccccttc ttcgggaaac gaggaggaat cactttctct ggaggcgaac
     6601 cgacgtttca ggcgaaagca ctcgtcccgc tggtccgcga actgaaagaa aaaggcatcc
     6661 atgtctgtct ggacagcaac ggaggacttt ggaacgaaga cgtagaagaa ttattcaagc
     6721 tgaccgatct tgtgttattg gatataaagg aattcaatcc caaccgccat cagacgctca
     6781 ccggaagaag caacgagcaa accatccgca cggccgcctg gctggaagaa cagggaaaac
     6841 ctttctggct gcgttatgtg ctagtgcccg gatacagcga ttttgaagaa gacatacgcg
     6901 cactgggaga agcactcgga aaatacaaga tgatccaacg ggtggaaata ctgccttacc
     6961 atacactggg cgtacataag tacgaagcga tgggacagga atacaagatg aaaggggtaa
     7021 aagaaaatac ccccgaacag cttgaaaaag ctgcggaggt attcaaagag tatttcacta
     7081 cggtagtagt taattaatgg agaattctcc aatgacctca aagcaagggc attctttaat
     7141 ccgttcccaa ggatctacga tcccattata gttggtgtcg ggacttaaat cccgatgccc
     7201 tactacttta gcttccggat aacgctgcaa caattcgtgt accaagcgat gtagcgcctc
     7261 cttctgacgg ggtgtacgcg tatccgccgc ttttccattc tcatccagac cgccctcata
     7321 gcatacacct aagctgatcg cattgtagcc acgtgcatga gctccgaccg tatcttcatc
     7381 ccgcatcggc tcaatctcgc ccgacttgcg tatataataa tgataccccc agcacgaaaa
     7441 gccacgataa cggtgagccg tatccacatc ctttgccgta aagtcgcaat cgacacgggt
     7501 ggcggaacaa tggatcacaa tcagactaat ctttctcatg ttccttttcc ctttccgtcg
     7561 ttttcacttt gcacacctcc ttacaagtag tatgatagcg cacttctctc accaccttgt
     7621 cccgctttct ctttccgaag aaaggaatca gatacatgat cacatctaaa atccggttta
     7681 ctatttcttt catcttatca aaatattaat ggaagttatt ctaattcgtt attaccttga
     7741 cccgtctgcc aattataccg tagggtccgg agcctcttca tcaccggagc catcaccacc
     7801 ggaatccgga ttcttgtcag ggtcttctcc cccgccatcg cctgcacccg cctgcgccac
     7861 cgcacgagtc agcacttgct ggtaactcag aatcttcatc aattccgcca gcgttttacc
     7921 ggggcggaaa ataagatgcg cccccttaat catcgaaccg gaaaattcct tgaccgatgc
     7981 cgcaccttca ctgttcagtc ctatctgcaa actgcccaaa tcacccagtc tcgcaattct
     8041 tcctgccttc aacgcacgct tcacttcgta aagaataccc gaaatagccg cacgtacatc
     8101 cgtttccgta caagtagaac gactggtgat cgcttcgcac aactcttcaa agtccagctc
     8161 acccgacgcc tgcgcctgtg cataatactt tgccggttca ctcttttttg caggattctt
     8221 gcgcggcacc actgaataag atactgtcat tgccataata aaataatttt aaagtttata
     8281 atacgtagga tgcatccctt tcttgttaac agcacaaaga taaggatagc cggacaagcc
     8341 atattcccca acgaagtttc ttgattccca acgaataaaa atgaagtcaa acctttgaaa
     8401 aacaaggaat tttatgtaac tttatagcat aaaacaagaa gaaaacatca tgaattacaa
     8461 agaagattct ttccttatcc gcacctatac caaagcggaa ctggctcacc tttacaatcc
     8521 ccatgtctgc ctcaaagttg ctttacaaat acttcgtcgt tggattattt acaacctccc
     8581 tctcctgcac gaactcgaac aggaaggcta ccgcgcacgc aaccgtctcc tttcgccgaa
     8641 acaagtggca actatcatac actttttggg cgaaccgtag taacttattg ccattttata
     8701 caaagttcct ttacacattt ccgcaaagaa gttcctttgc atcgacaaac aataatcaaa
     8761 ataaaaatga aacatttcac catatttcaa ggtttctact acgcaatagc agagatgacc
     8821 gaagaagaaa tagtgtccac tatcggcagt tttacctacc gggaaaaagt cgaagaaata
     8881 cgccgcatct ttgcagagca aggagaaaag gctgccaatg agaagaaaaa agaattgccg
     8941 gcaatcgcct tctccgccag ctaccgagga aggcgtacca aagtgaacct cgtcaaatat
     9001 ctgggacaca tcgtgataga catcgaccac ctcagcaaag aagaattggc acgcatcctc
     9061 cctatcatca agagatgcga ttacacccgc atcgccttta tcagtcccaa agggatgggc
     9121 gtgaaaatca tagtgcgcgc atgccatccg gatgagacat tgcccgaaac ccttcaggaa
     9181 atagaagact tccatcatgc agcttacacc agactcgttt ctttttacac cgaactctgt
     9241 cggatagaaa tcgacacctc cggtcaggat gtggcacgca cttgtctgtt ctcttacgat
     9301 ccggagatct atttcaatcc gaacgctgac gcttttcttg tagatcaacc tcaggcatcc
     9361 tacaagattt caaatcgtaa aaatctctcc ggcagtaaac aacagactcc tccggacggc
     9421 accccgacga atgaagacac agcactcaac gcccattccg ccaacgcttc tttggtgttg
     9481 actttaactt actatcacaa caagtccgaa aaatacatag caggcaaccg gaacaattat
     9541 ctgcaccatc tctcatgtac cttcaatcgc tacggcattc cgcaggagga aacatccgcc
     9601 tttatcaaaa gccagtttac agactttccg gcggacgaga cagtctcttt gatcaatagc
     9661 gcctacgctc ataccgacga atttaatacc tgtaaactga atggcacgca gaaacgaata
     9721 ttacggatag aacaatatat cagcgagcac tacgaaacac gctacaatga agtgctgcat
     9781 atcatggaat atcgcagaag gcgtcccgac accgagaaac cggagccttt ccgcatcttg
     9841 gatgagatga tggaaaacag tatctggata gaaatcaacg agctgggata tccctgcact
     9901 gtcaaaacaa tcgaaaatct gatttactcc gatttcagcc agtcgtatca tcccattcgc
     9961 gagtattttg aattactgcc cgaatgggac ggaaccgact atatccgtat cctggcggat
    10021 agtgtccaga cgagtcatca ggagttttgg gcggaatgcc tggaacgtta tctggtggcg
    10081 atgtgcgcag cggctactca ggagaatatt gtcaatcaca cggtacttct gctatgcagc
    10141 gagatacaga acataggaaa gactaccttt atcaataatc tcctgcctcc cgaactgcgt
    10201 gcttatctct ctaccggact aatcaattcg aacaataaag atgatttagc caaaataacg
    10261 caggccatgc tgatcaatct cgacgagttt gaagggatga gcggtcggga actgaatgca
    10321 ttcaaagatt tggtaacgcg caaagtgatc agtttccgtc tgccatatgc acgccgttcg
    10381 caaaacttcc ctcatacggc ctcttttgca ggaacctgca attatcagga agtgcttcac
    10441 gacacgacag gcaaccggcg tttcctttgt tttcatcctt attccatcca atttattacc
    10501 atcaattatg cgcagctcta tgctcagatc aaatatctgc tgaataagcc ggggtaccaa
    10561 tactggttca cgcaagcgga caatgaacgg cttgaagaga ataacgaggc tttcatcttt
    10621 cattcaccgg aagaagaaat ggttcttacg catatccgca agccggaacg ttttgagaag
    10681 gtttattatc tgactgtcag tgagattgcg gaactaatac gtgagcgtac cggttatcag
    10741 tattccatcg gatcaaaaat acagttgggg aaggtgatga ctaagcacca ttttgaatct
    10801 aaaaaaggaa ataacgggcg ccgatatgcc gtatttatta tagatatcga gcaggtaaaa
    10861 tcaaacaggc tgtatgaata gaagcgggaa agccttgtga atatagcaaa atgcagagtc
    10921 atcttgacag atactctgca tttattgttt ttacaaaatc attgaaaatt cgattttaca
    10981 gcctaacgca ttcattatac gatagaaagt agatacttta ggctctgtct gaccactttc
    11041 tactcttgaa atataagaac ggtcagagcc gatacgccgg gctaattcag cctgagtgat
    11101 tttagccttt tttcttgcgt cctcgataat ctgtcctgta taaaaggcgt aggccttttc
    11161 ttctgcctct gcacgagaag ctgttccttc cttaccaaaa cgctcatcta ttaatgcact
    11221 gacattaaag aattcctcat ttgtttttgc ttccataata ctcctttctt aatatctttg
    11281 ctttatcaat ttctttcttt ggtgtttttt cggttttctt ttgaaaaccg ttaaacagaa
    11341 tcacaatacg cccttcgtcg aaacaaaaga atattctata tatattgctt tggtactcga
    11401 tacgaagttc ataaagtcct tcttctatca accgcataaa tttcaaaggt attctgtctt
    11461 gtgtctgcaa taacattagc acatacaata tcttatcttg ggtgccagca tctaaatttt
    11521 caaagaattc tttgaagtat cctttatatg ctattatttc tcttttcata acgcaaatat
    11581 aagaaatgtt gttcaactat acaacacatt tcctcgtttt atattatttt tcatcatctt
    11641 cacccacaaa agtgagagga gtgagagagg aattgaaact ttttctattt tatttcttta
    11701 tttctacttt ctatatttct ctaaaaaaaa tacgaatgtt agaaatcctc tctcactcct
    11761 ctcacttttt accttttctt tctccaaaaa gacggcggga aatcggaaaa acacaaccgt
    11821 cttttttcga tttctcaccg cattttcaaa tcaacccacc aattgaagca gacttcagga
    11881 aatatttgtt atctttgatg tgcaaaagat caaaagaatc agatatgggc aacttgatgc
    11941 gtaaacttcc tattggaata caaacctttg aagatatacg aaggaagaat atcttattgt
    12001 aaagatcgga gtggaattta gttcagaaag ccggaactta aaccgttggt taatagagac
    12061 tattgagtaa tagaaaccca agtggcggca atctgcaaca agtttccatc cagatttccg
    12121 ccactttttt aattcaaccg ttcagcgatg gaaacagatt atttaaaatc tccctccgaa
    12181 taatctgaaa actccccggc acgttctttc ttctcatacg agaccaacgt ttcgatacta
    12241 agcgctttcc cgttcttagg gcttatgaca tctatcacac ttgacaagga ccggaacgtc
    12301 tgttcgcaat tcgcgtctcc attatacgtc aacctccccc ggtcaatagc acctagaatg
    12361 acagaaatgt accgtttcgg atctccccga tattcgataa cagtgggcgt catttgttct
    12421 tcttcccgaa tcagttggac gacaattctt ttttttggtc aatcagctcc aacagttttt
    12481 cactatgcac actgatttgt gcatctactt cacgaagttc attcttcaat gaacaaaaca
    12541 attcatcact caatgaattt tccataaaaa cgatttttat taattataaa aaagccattc
    12601 cggaaagcac agctattgcc tgcttcccga aatggtgact aataccttca aaaacaatga
    12661 ctctattttt actttaatgt actcaattta tttcacttct tttctctcct gcattccaaa
    12721 ccaacaaagc aaacactact gaaagcaagg ctgcaccaat ccaaaaccaa ttgatatatg
    12781 taaaatcgta aacttctact ccattttgca ccgtcttctg accttcgatc agaatgccac
    12841 tcatcacatc ctgcaaaccg gctcctatat aactcgctat accgacaact cccaaagcgg
    12901 ctcccgaagc attgcaggga gcaatatcga ccgccatcag tcctcctaaa aaacaaatca
    12961 gcactccaat gcccaaaccg aagagcacca tcgccaaagc atccacccaa aaatgtaccc
    13021 ccggaaccaa tagaaacaaa caaagagcag acacattcat taatccgaat atcaaagccg
    13081 gaacattacg actgccagca aaaaacttat ctgaaataat acctgagaaa accgtaccta
    13141 caattccgca tacagaactg atagatataa taaaactagc atccaaagta gaataacctt
    13201 tttgcgcttc cagatagaaa acaccccagc tattgactgc ataacggctg atatacataa
    13261 aagcactgga taatgcaaga atccaaatag caggattctt caaaactgct ttctgagctt
    13321 tattgaattc ctcggtttgt ttaccggaaa cggaatgagc atctgacgtc ccccgccgat
    13381 ctagcaaaaa gccctgactt tgaggcgtat cacgcataaa agcaagcatc atcagaaaac
    13441 caagcaaacc aatcactccc gcaccgatca tcccataacg ccatcccatc caactgacca
    13501 gcaaagcgat ggatataaaa gtcagagctt cacccaaatt gtggctggcc gaccaaaagc
    13561 cataaaaagt acctcgctct ttactactat accaacgagt cagcgacaca actcctgatg
    13621 ctgcccccat cgactgaaac caaccattca acccccaaag gagaacaaaa gcaaagaagg
    13681 aattcgtgaa tcccagacat aagttgatca gagcagaaca caataatccg gtagacataa
    13741 aacgctttac attgctacgg tcagcaagaa agccattggt cagcttaccg acggcatata
    13801 cgaaaaaaag gcaggaaccg ataatcccca gttgggtttc ggtaaaaact ccgtcttcta
    13861 caatcggttt acggattaca ttcatactca aacgacaaac ataataaatg ccatatccgg
    13921 tagtggcaga cagaaaggta gcccaacgaa tacgcttgaa acggacagag cgttccgaat
    13981 cagtctctcc cccggacacc ggaggagaga ttttataaaa atccaatagt ttaaatccca
    14041 taaagaagtc tatattttaa tgatacgcat cttgcccgtt ttcactacgc ttcttacgcg
    14101 attgcaaata ttccagcaga taggcagtac ggtctgtctg aatgatggcc gctccgagtg
    14161 tatcgatcag ataaccatat ccttcgtccg gattctccaa cgatttatca tcatcatgtc
    14221 cgccagccat cgtatcccac aacgtattat accagatttt actttttcct ttcaacttcg
    14281 tttttacttg cttggggacc tggcaggtat ccgatacaaa tagaagttca aaagctacgg
    14341 gatgcagctc cgtcataaaa tcatccagtt gcttcattgc tcccggctta tccaaatgaa
    14401 tgataggcat ataaatgata cggtccagat atttacctaa gtcgttcttt acgtctgcca
    14461 caggcttgga acctttcatg ataatctgat ccactgttcc cgtcttttcg aggatgggga
    14521 aaatctcgtc aaatatcgga tatgctttat ccagattgac catcacacga cctttggcaa
    14581 cccataaagc ctcttccaaa gtaggtacac gatgcttggt tttgagtgcc gctccattct
    14641 tcagatagag tgtccggata gaatccaatg tccattcggc tacctttcct tttccggtag
    14701 tcgttcggtc cagcgttttg tcatgcatca ggatcaattg accgtctttg gttttctgaa
    14761 catccagctc cactacgtca gctcccagac gaatggaact ttcaatagcg gcaagtgaat
    14821 tttcgggtgc gtaacgccag tctgcccgat gagctacaac cgtgatttct ttattgtcag
    14881 ggttcgttat cttcgcataa atggctttca ccggttcgtc tgccgacagg cagaaaggaa
    14941 atgcgaataa gattcctatc attatatatt tcttcatatc tatatgtact attatctgta
    15001 tcctttagac tttaaatatt tggcagctac ttcagcatag tctgtttgca caatgttgat
    15061 gcgtttgtta atcattccca ccaaaccgga gtagttttcc gacaacatat tggtatcatt
    15121 cgctccgaca atgttggaga aaagaagcca gccttgatct ttaatctcat taaccatcgt
    15181 tccacccata gcgtctgacg tagacagctg catcatttgt acattatcag tgtaggatga
    15241 ggagaagtat gtgatatcat cggcggcttt tgccatcggg tgcaacagca aactactgtt
    15301 ggctgtcttc aaatcaaatg cataattgcg attgttggat acatacagca aagtggaacc
    15361 ttccatatcc aattttttaa gcaatgcgac gatcgtattt accgcaacat tcttgttgac
    15421 aatatccaga ttataataaa cttttccttt tcccttcttc atcgcttcct ccaaagtcgg
    15481 gattcgttcg ccagttatat tgccggatgc atctttcaga taaaattgtt gtaattgctg
    15541 ataagtaaag tctcccaccg caccgctacc gtttgttgtc cggtcgatgg tgttgtcgtg
    15601 catcaatacc aacacaccgt cagaggtcgg ccgtgcatcc agttcgatca tctcaactcc
    15661 tgctttgacc gagtgttcta tcgcaggtaa cgagttttcg ggaatcccct ctttcatccc
    15721 tttttgggta tttccacgat gcgcgcagag ccacacttta taagaggtgc tttcaaacag
    15781 actctttaaa tctgctttca aattccccgt cataggcaac tgtcctcctt cttctccacc
    15841 gggattctct ccattccctc ccgattgggc tccggagtga cgtctgtcct tccctttcat
    15901 cggccaggca gaggttgcgg ccccggtaat tccctcatct tccaaagcta ctaacacgct
    15961 ctttgtaggg tccaccgtat tggtgactcc gatataaatc gctccatccg gtccgatggt
    16021 aggcgaactc cagattttac cgattcccgc ttcccaatct ccttttaaag gagagtcact
    16081 ttcactaatc aacgcagcaa ggtctttttt cagaatcaat tgttcatccg attcttccgg
    16141 tttaatgata taataattgc cggactgggt gccgaaatgt atgtttcctg cttgatcaat
    16201 tgccgcacaa ccgcttacat cttccgcaat gccgtaatgc cattggatag ctcctcccgg
    16261 agacaaagag atgattcctc cggttgcttc ccccggagca cgtttcactg taacgataat
    16321 gcttccgtcg agtcctatca caacaccgcc ttgatccagc gtgccgacat tgcccaaagg
    16381 agtacgccac ttctccactc catcacttcc tatagcaaat gcgctacttc ccattcctgc
    16441 aaacgtagct gttccgtaaa tagtaccaac ctcatctact gccggagaac cgttcatatt
    16501 ttctgacggc ttatcatcgc cggagctaaa tacctgccaa gcccacatta catttccacc
    16561 ggcattcaac gcagaagcag aagccccgaa caatccattc tttccgccac cccaaactaa
    16621 agtgttgttt gccaatacta ttcctgcaga tactcctccg gaaggacctc cggaattatc
    16681 cgcattcgct acgtatccta cccgatagcc ggtcacctta tctactgcaa gtactgatcc
    16741 tgtagaaccg ccattaccca tatatacatg attctcccca atggcacagg tcaggtaatt
    16801 gatacggggt gtggaagctt ttcctttatt ccagaagcca ttttcagcgt cacctgccac
    16861 cagccatttc ttactcccgt ccggatttat tgcatacaca cgtcctactt tgccactggt
    16921 gtctccggtt cctacgtaga ttgttccgtc tatttcaatg cttggagtag tatgcgtatt
    16981 tccggatggt gcatcgccgt cagcagatgt ccaaaggtca aattcccaaa gctggtctcc
    17041 tgtcgctgcc gaaaatttac gtaaataatg atcattggaa gtcatataca ccccatt
//
