LOCUS       c00051_gnlPro..        10569 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EPKABKHL_51.
ACCESSION   c00051_gnlPro..
VERSION     c00051_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:48:50
            Original ID  :: gnl|Prokka|EPKABKHL_51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10569
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10569
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[98:3042]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      99..3042
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /neighbourhood="10000"
                     /product="Others_HGD_unassigned"
                     /protocluster_number="1"
     cand_cluster    1..10569
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D,
                     HleuD1, HleuD2, HleuS1, HleuS2, Lactoyl-CoA1,
                     Lactoyl-CoA2]) and minimum(1, [ACP_syn_III, ACP_syn_III_C,
                     AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG,
                     Biotin_lipoyl, Carboxyl_trans, CoA_trans,
                     CoA_trans_230_acto, CoA_trans_6_Glutaconate, CoA_transf_3,
                     ECH_1, ECH_2, ETF, ETF_alpha, FGGY_C, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, Mal_decarbox_Al, Peptidase_M22,
                     Peptidase_M23, Thiolase_C, Thiolase_N, ketoacyl-synt]) and
                     not (minimum(2, [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /kind="single"
                     /product="Others_HGD_unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10569
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Others_HGD_unassigned"
                     /region_number="1"
                     /rules="(minimum(1, [HAAA1, HG2B1, HG2B2, HGD-D, HleuD1,
                     HleuD2, HleuS1, HleuS2, Lactoyl-CoA1, Lactoyl-CoA2]) and
                     minimum(1, [ACP_syn_III, ACP_syn_III_C, AcetylCoA_hyd_C,
                     AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2,
                     AdoHcyase_NAD, AlaDh_PNT_C, BcrAD_BadFG, Biotin_lipoyl,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_6_Glutaconate, CoA_transf_3, ECH_1, ECH_2, ETF,
                     ETF_alpha, FGGY_C, HCDH, HCDH_N, Hacid_dh, Hacid_dh_C,
                     Mal_decarbox_Al, Peptidase_M22, Peptidase_M23, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and not (minimum(2,
                     [AcetylCoA_hyd_C, BcrAD_BadFG, CoA_trans,
                     CoA_trans_230_acto, Mal_decarbox_Al]) and Lactoyl-CoA2 and
                     Lactoyl-CoA1) and not (minimum(4, [ACP_syn_III,
                     ACP_syn_III_C, Acyl-CoA_dh_1, Acyl-CoA_dh_2, AlaDh_PNT_C,
                     BcrAD_BadFG, ECH_1, ECH_2, ETF, ETF_alpha, HCDH, HCDH_N,
                     Hacid_dh, Hacid_dh_C, IlvN, NAD_Gly3P_dh_N, Thiolase_C,
                     Thiolase_N, ketoacyl-synt]) and HAAA1 and not HleuS1))"
                     /tool="gutsmash"
     CDS             complement(99..1778)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: BcrAD_BadFG"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_1"
                     /sec_met_domain="HGD-D (E-value: 9.4e-18, bitscore: 53.8,
                     seeds: 370, tool: rule-based-clusters)"
                     /sec_met_domain="BcrAD_BadFG (E-value: 6.5e-66, bitscore:
                     211.4, seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTYYVCKYTPIELLESLGGECENFNHMPEGFDLADQVSHPNIC
                     GFGKTLLEGVMEGKIKELVLVSCCDTIRSVYDILLESGKLDFLYILDVLHCDSACSRER
                     MAVQLKGLAKAYAQYKGTEFDAGKFRAAFHAQEKITKSHIAVLGARMGQELFEMTSKAM
                     PLPVENDTCVHNRSVGNILPPEGASFDELMDWYAGEILGQIPCMRMMDPTGRKKLYNDP
                     SVAGIIYHTVKFCDFYSFEYAEIKNHTDVPLLKIESDYTIQSSGQLLTRLEAFAESIQP
                     ETLEQTIDGDTKGERKMGKGYFAGIDSGSTSTDVVILNKDHEIVTSIILPTGAGAAIGA
                     DRALAEALKEAGLQREDIDALVTTGYGRTAIKNGDKSITEITCHARGAHFLNPEVRTVI
                     DIGGQDSKVIRLDENGAVANFVMNDKCAAGTGRFLEMMARTMEMNLDQMSECGLEFKED
                     ITISSMCTVFAESEVVSLIAQNKATDDIVHGLNKAVAVKTAALTRRVGGEEKYMMTGGV
                     SKNKGLVKTLEEKLGTKLVISDKAQLCGALGAALFAADMADV"
     CDS             complement(1771..3042)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Others_HGD_unassigned: HGD-D"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_2"
                     /sec_met_domain="HGD-D (E-value: 2e-56, bitscore: 180.9,
                     seeds: 370, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIETFGHYVENLTDKKPQSARRLLKTGWEAQNLKFRYMQDKRL
                     MPADRHLANLMMDTMLRPLQKPEDSVIVSIFTPCEMMQEVGLHPYNVEGFSCYLSASKA
                     ERTFLQQAENQGIAETLCSYHKTFLGAAQKGLLPKPKCIVYTNLTCDANLLTFRTLADF
                     YQVPVFAIDVPWNQTTENVQYVADQLKDLKIFLEKNTGKTISEDRLKERLACSKRTLEN
                     YKKYQQMRADRYVPSDLVTPLYAGMTNNILLGTAEEEKYTQMLLEDIKKAPAAKGKHIY
                     WMHTIPFWSDAVRQELCFSEKAQIVGCELAETCEPDFDPENPFEAMAERMVYHSLNGSA
                     LRRIEAGIRHAKQAGADGAVWFGHWGCKHTLGAAQLAKKKFEEAGLPLLILDGDGCDRS
                     HGGEGQTSTRLGAFLEMLGGAENE"
     CDS             3286..5100
                     /locus_tag="ctg51_3"
                     /transl_table=11
                     /translation="MRSLTVYLKNYKKESILAPFFKFLEVVFDLIVPIVIAQIIDVGIA
                     NHDNGYIVQRFSILILMAALGLASTITAQFFAAKASVGFATELRQAVYDHVQHLSYTEL
                     DTLGTDTLITRLTDDVNQIQNGLNMGLRLLLRSPFIVLGSMVMAFTIDFKCALVFAVAI
                     PFLFLVVFVIMFLSIPLFKKVQGKLDTVTGLTRENLTGVRVIRAFCREKEAVAEFDTRN
                     QELTKLNLFVGKLSALLNPVTYVLINIATVILIQKAGVEVNLGGMQQGQVVALYNYMAQ
                     MIVELIKLASLIITLNKSAACAGRVADILKVKSTMDYPSSSTYSAQISKDLATATADAS
                     LSENAIVFNDVTFEYSKAGAPSLSHISFSVKKGQTVGIIGGTGSGKTTLVNLISRFYDA
                     SKGTVLLDGQNIENYTRSDLRSRIGVVPQKAALFKGSIRDNLKWGREDASDEDLWQALT
                     TAQGKEVVEGKPGQLDFMLEQNGKNLSGGQKQRLTIARALVKKPEILILDDSASALDFA
                     TDAALRKSLNRLDWKVTTFLVSQRSSSIQQADLILVLDNGTLAGKGTHAELLRTCDTYR
                     EIYFSQFPEERARYSSVSAGNIMKEVTV"
     CDS             5097..6863
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     283.7; E-value: 1.8e-86)"
                     /gene_kind="resistance"
                     /locus_tag="ctg51_4"
                     /transl_table=11
                     /translation="MSRLTIKDPAKSKSSETFLKVLRFIGRYRFLLILSIILAAVSVIL
                     QLYVPILFGNAIDQVIAQHQVNFEMMWYYLSRILVMVILSSAATWLMNVINNRMTYQTV
                     KDIRAKAIRHIQVLPLSYLDGHSTGDIISRIIADTDILSDGMLLGFTQLFSGIVTIIGT
                     LIFMFSKNFWITLMVIVLTPVSFLVAKFISSHTFQMFRKQSDARGRQTALIEEMIGNQK
                     VVQAFGYEEKSSERFAKVNEELQECSLKAVFYSSLTNPSTRFVNNVIYACVALVGTFII
                     PGGRLTVGGLSVLLSYANQYMKPFNDISSVVTELQNALACAGRIFDLLEEEPEVAEASE
                     TLKDVKGEVDIKNVCFHYDESKKLIEDFNLHVKPGMRVAIVGPTGCGKSTFINLLMRFY
                     DVNFGSISVDGKPIRDITRHSLRSSYGMVLQETWIKNGTVRDNISIGKPEATDTEIIEA
                     AKLTHSWEFIRRLPKGLDTMLNEDSLSQGQKQLLCITRVMLCLPPMLILDEATSSIDTR
                     TELQIQEAFERMMEGRTSFIVAHRLSTIRNADLILVMKDGSIIEQGTHDELIAKGGFYH
                     TLYNSQFAKVSE"
     CDS             complement(6951..8738)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_5"
                     /sec_met_domain="Peptidase_M24 (E-value: 3.7e-43, bitscore:
                     136.5, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVKERIAALRARMKETGIDAYLIPTDDFHGSEYVGEYFKCRKYI
                     TGFTGSAGTAVIMQDMAGLWTDGRYFIQAADQLEGTGITLFKMGEPEVPTVHEFLKKNL
                     TQGRCLGFDGRTVSAKEAAELEKMLDENGVSLSVDHDLAGDIWENRPVLSCEPVTELDI
                     KWAGESRADKCARIRKAMEKKGADLFVLTSLDDIAWLLNIRGGDIHCCPVVLSYLVMTK
                     TEIRLFANEKAFQTDVLEALEKDGVTLFPYDGIYEYVKTFKKDKKVLLCKKKVNSRLVS
                     NIPADTRILDEENLTLLPKATKNPVEVENERIAHIRDGVAVTKFIYWLKKNVGRIPITE
                     LSAAEKLYEFRSEQEDFIDNSFDPIIAYGKHAAIVHYFATPETDIPLEPSGFLLADTGG
                     HYKEGTTDITRTVVMGPTTEEEKKYFTAVLRGTLNLGAARFLHGCTGVNLDILARQPLW
                     EMGENFKHGTGHGVGYLLNVHEGPNSFRWKIVPGGNAVLEEGMITSDEPGYYREDGFGI
                     RHENLMVCKKAEKTEYGQFMCFEFLTMVPFDLDGVVPELMSARERNLLNDYHAQVYEKI
                     SPYLNEEEKEWLKDATRAI"
     CDS             complement(8735..9583)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_6"
                     /sec_met_domain="ATP_bind_3 (E-value: 6e-08, bitscore:
                     21.6, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLEHLKEYLKGLGSVAVAFSSGVDSTFLLKVAHDVLGDKAIA
                     ITAQSCSFPKRELNEAKAFCEKEGIQHVICQSEELEIEGFSKNPPNRCYLCKKELFEKI
                     GDIAKKNGIEYIAEGSNMDDNGDYRPGLIAVKELGVKSPLCEAKLTKAEIREYSKELGL
                     PTWDKQSFACLSSRFVYGETISEEKLGMVEKAEQLLLDYGFHQVRVRIHGSLARIEIMP
                     EEFPKLLEKNVREDIAKKFKEYGFTYVTMDILGYRMGSMNETLGENDKTTADSSLKGKN
                     E"
     CDS             complement(10053..10568)
                     /locus_tag="ctg51_7"
                     /transl_table=11
                     /translation="SMAPEYPIIKEEKVEPEVYRVINAILETEQSDITVAQAYLQIVLA
                     RCIGKLNLVEKSNVGSNDLIYQTVSYISANFKKKFSLEEMAKDLGVSKYVLSRLFSKTF
                     HRNFNQYLNDARLNYACHRLENTSDSITNICLDSGFESQRTFNRVFKERYKISPSDYRS
                     TCLKDMLS"
ORIGIN
        1 tttatcacat ccaaatcttt ttattaatat ttttcatcaa agcaatgttg ccaaatagct
       61 taagttaatg acattggtag tgaacagtaa ctaaaaattt acacatcagc catatcagcc
      121 gcaaacagtg ctgcgccaag tgcaccgcaa agctgagcct tgtcactgat caccagcttt
      181 gttccaagct tctcttccag tgtctttacc agacccttat tcttagaaac accaccggtc
      241 atcatatatt tctcctcacc gcccacacgt ctggtaaggg cggcagtctt tacggcaacc
      301 gccttattca ggccatggac aatatcatct gttgccttat tctgggcgat cagtgataca
      361 acttctgatt ctgcaaatac tgtacacata ctggaaattg taatatcttc tttgaattcc
      421 agcccacatt cgctcatctg atctagattc atttccatgg tacgtgccat catttccaga
      481 aatcgtccgg ttcctgccgc acatttgtca ttcataacaa agtttgcaac tgcaccgttc
      541 tcatccagtc ggatcacctt gctgtcctgt ccgccaatat caataacagt acggacttcc
      601 ggattcagga aatgcgcacc ccttgcatga caggtgatct ctgtgatact cttatcacca
      661 tttttaatag ctgtacgtcc gtatccggta gtaaccagcg catcaatatc ttctctctgc
      721 aatccggcct ccttcaatgc ttctgcaagg gcacggtctg ctccgatagc agctcctgct
      781 cctgtaggca ggataatgct ggtcacaatc tcatgatctt tatttaaaat caccacatct
      841 gtactggtgg aaccactgtc aatccctgcg aaataacctt ttcccatttt tctctctcct
      901 tttgtgtctc catctatggt ctgctccagt gtttcaggct gaatgctctc tgcaaaagct
      961 tccagtctgg taagaagctg accgctgctc tgaatagtat aatctgattc aatttttaaa
     1021 agaggtacat ctgtatggtt cttgatctca gcatattcga agctgtaaaa atcacaaaac
     1081 ttcactgtat gataaataat ccccgcaaca gacggatcat tataaagctt cttacgacct
     1141 gtcgggtcca tcatacgcat acatggaatc tgccccagaa tctcacctgc ataccagtcc
     1201 atcagctcat caaaagaagc accctccggt ggaagtatat ttcccacaga acggttatgc
     1261 acgcaggtat cattctctac aggaagaggc atagccttgc tggtcatttc aaataattcc
     1321 tgccccattc tggcgccaag cactgcaata tgggactttg tgattttctc ctgtgcatgg
     1381 aaagcagccc ggaattttcc ggcatcaaac tctgtgcctt tgtactgtgc ataagccttc
     1441 gccagccctt ttaactgtac agccatacgc tctctgctac aggcactgtc acagtgaagc
     1501 acatccaaaa tatagagaaa atccagcttg ccgctttcaa gcagaatgtc atagacactc
     1561 cggatagtat cacagcagct caccaggaca agttccttga ttttcccctc catgactcct
     1621 tccagaagtg tttttccaaa accgcagata ttgggatgtg aaacctgatc ggccaggtca
     1681 aatccctccg gcatatgatt aaagttctca cattccccgc caagagattc cagaagttca
     1741 attggggtat atttacagac atagtaagtt ttattcattc tcagcacctc ccagcatttc
     1801 cagaaaagct cccagcctgg tggaagtctg tccttctcct ccatggcttc gatcacaccc
     1861 gtcaccgtcc aggattaaaa ggggcagacc ggcttcctcg aacttcttct ttgcaagctg
     1921 tgccgcacca agcgtatgtt tacatcccca atgtccaaac cacacagcac cgtctgctcc
     1981 tgcctgtttc gcatggcgga taccggcttc aatccttcta agggcacttc cgttcagtga
     2041 atgatatacc attctttctg ccattgcttc aaaggggttc tcaggatcaa aatccggctc
     2101 acaggtttct gcaagttcac atcctacgat ctgggctttc tcactgaagc aaagctcctg
     2161 gcgcactgca tccgaccaga atggaatggt atgcatccag taaatgtgtt tccctttcgc
     2221 tgccggtgct ttcttaatat cttcaagaag catctgtgta tacttctctt cttctgctgt
     2281 tcccagaagg atattgtttg tcattcctgc atacaagggt gtgaccagat cagagggcac
     2341 atatctgtct gcacgcatct gctgatattt tttgtaattc tccagagtcc gcttactgca
     2401 ggcaagacgt tcctttaatc tgtcctcaga gattgttttt cctgtatttt tttccagaaa
     2461 tatttttaaa tcctttaact gatctgccac atactgtaca ttctctgtgg tctgattcca
     2521 tggtacatca atggcaaata caggtacctg gtaaaaatct gccagggtac ggaaagtgag
     2581 caggttagca tcgcaggtca ggttggtata aacaatacat ttaggctttg gcagaagtcc
     2641 tttctgcgct gcaccaagaa atgtcttgtg ataactgcac agtgtctctg caattccctg
     2701 attctctgcc tgctgcagaa acgtcctctc tgctttgctt gcagaaagat agcaggaaaa
     2761 tccctctaca ttatagggat gtaatcccac ctcctgcatc atttcgcagg gtgtaaaaat
     2821 acttacaata acagaatctt ccggtttctg aaggggccgc agcatggtat ccatcatcag
     2881 atttgcaaga tgcctgtctg caggcatcag tctcttgtcc tgcatgtaac ggaacttcag
     2941 attctgcgcc tcccagccgg tttttaacag ccgtcgggct gactgaggct ttttatccgt
     3001 cagattttcc acataatgac caaatgtctc aataatctcc atagtctgtc tcttcctcat
     3061 tatggtaata ataatttatc agttgccagc gtacaaatag cgctacggaa tattttagta
     3121 atatcttttt ttgaagtcaa gctgaatttt ctccaaagtt catctgtttt tgcacattct
     3181 tcttgacaaa aaagtcttaa atgatacact tttgaatgta ttatttttca aaaaaaggaa
     3241 ggaataatat aggaaagatt tttacgaaag gaaggaattt ttaaaatgcg ttcattgacg
     3301 gtttatttaa aaaactacaa aaaagaaagc atccttgcgc cattttttaa atttctggag
     3361 gttgtatttg acctgatcgt acctatcgtc attgcacaga tcatagatgt aggtattgca
     3421 aaccacgaca acggatacat tgtccagaga ttttctattc ttatactaat ggcggctctt
     3481 ggtcttgcca gtaccatcac agctcagttc tttgccgcta aagccagcgt gggctttgcc
     3541 acagaattaa gacaggcagt ttatgaccat gtacagcatc tgtcctatac agagttggat
     3601 acactgggaa cagatactct tatcacaaga ctcaccgatg atgtcaatca gattcagaac
     3661 ggattaaata tgggacttcg tcttcttctt cgaagtccgt ttatcgtact tgggtccatg
     3721 gtcatggcat ttaccattga ctttaaatgt gccctggttt ttgctgttgc gatcccgttt
     3781 ctgtttctgg ttgtctttgt cattatgttt ctcagtattc ctctgtttaa aaaagtacag
     3841 ggaaaactgg acacagtaac cggactgacc agagaaaacc ttacaggcgt ccgcgttatc
     3901 cgtgcattct gccgcgaaaa agaggcagtt gcagaatttg atacccgcaa tcaggagctg
     3961 acaaagttaa atctctttgt aggaaagctt tccgctttgt taaatccggt cacttacgta
     4021 ctgatcaata ttgctactgt tattctgatc cagaaagcag gagtagaagt aaatcttggc
     4081 ggtatgcagc agggacaggt tgttgccctt tataactata tggctcagat gatcgtggaa
     4141 ctgatcaagc ttgcctccct gatcatcacc ctgaacaaat ctgcagcctg cgcaggacgt
     4201 gtggcagata tcctgaaagt gaaatctact atggattacc cctcttcctc cacatattct
     4261 gctcagatat cgaaggacct tgcaacagca actgctgatg catcactttc tgaaaatgcc
     4321 atcgtattca atgacgtaac ctttgagtac agcaaagccg gtgcccccag tctttcccat
     4381 atcagttttt ctgtaaaaaa gggacagacc gtaggtatta tcggtggtac aggaagcgga
     4441 aagaccactc tggtaaatct gatttccaga ttctatgatg ccagcaaagg aactgttctg
     4501 ctggatggtc agaatattga aaattacacc agaagtgatc tccgctccag aatcggcgtt
     4561 gttccacaga aggcagctct tttcaaaggc tctatccggg acaatctgaa atggggccgg
     4621 gaagatgcct ctgacgagga tctgtggcag gcacttacca cagcacaggg aaaagaggta
     4681 gtagagggta aaccgggaca gcttgatttt atgctggaac agaacggtaa aaacctttcc
     4741 ggcggccaga aacaaagact taccattgcc cgtgccctgg taaaaaaacc tgaaatcctg
     4801 atcctggatg acagtgccag tgccctggac tttgccactg atgcagcact gcgtaagtct
     4861 ctcaacagac ttgactggaa agtaactaca tttctggtat cccagcgttc ctccagcatt
     4921 cagcaggcag acctgatcct tgtccttgat aacggtactc tggcaggtaa gggtactcat
     4981 gctgaactgc tacgtacctg tgatacttac cgggaaatct acttctctca gtttccggaa
     5041 gaaagagcca gatactcctc tgtatctgca ggtaatataa tgaaggaggt gactgtatga
     5101 gcagattaac aataaaagat cctgctaaaa gcaaaagcag cgaaactttt cttaaagtac
     5161 tgcgtttcat cggaagatac cgttttctgc tgatcctcag tatcatactg gcagcagttt
     5221 ccgttatcct tcagctgtat gtcccaatcc tattcggaaa tgccattgat caggtcattg
     5281 cccaacatca ggtaaacttc gaaatgatgt ggtattacct gtcacgtatc cttgtaatgg
     5341 tcatcctctc ttctgctgcc acgtggctta tgaatgtgat caataaccgc atgacctacc
     5401 agacagtaaa ggatatccgt gccaaagcca tccgacacat tcaggtactt cccctctctt
     5461 accttgacgg acacagtacc ggagatatca tcagccgtat tatcgcagat acagatattc
     5521 tatccgatgg tatgctgctt ggatttaccc agcttttttc cggaatcgta acgatcatcg
     5581 gaacactgat cttcatgttc tccaaaaatt tctggattac attgatggtc attgtcctga
     5641 cccccgtaag ctttttggtg gccaaattta tttcttccca taccttccag atgttccgga
     5701 agcaaagcga tgccagagga cgtcagactg ctctcatcga agagatgatt ggaaaccaga
     5761 aggttgttca ggcttttgga tatgaggaaa aatcttctga acgctttgca aaggttaacg
     5821 aagaattaca ggaatgcagt ctgaaggctg ttttttacag cagcctgaca aacccttcca
     5881 cccgttttgt caataatgtt atttatgcct gtgttgcact ggtgggtaca ttcattatcc
     5941 ctggaggcag actgacagtc ggaggacttt ccgtacttct ctcctatgcc aaccagtata
     6001 tgaaaccatt caatgatatc agttccgttg ttacagaact tcagaatgct cttgcctgtg
     6061 caggcagaat cttcgatctg ctggaggagg aaccggaagt tgcagaggct tctgagacac
     6121 tgaaagatgt aaagggtgaa gtagatatta agaatgtgtg cttccattat gatgaatcaa
     6181 agaaactgat tgaggacttt aatctccatg taaaaccagg tatgcgcgtt gccattgtag
     6241 gacctaccgg atgcggtaag tcaaccttta tcaaccttct gatgagattc tatgatgtaa
     6301 atttcggatc tatttccgtt gacggcaaac cgatcagaga cattacccgc cattctctca
     6361 gaagcagcta tggtatggtg cttcaggaaa catggatcaa aaacggaact gtccgcgaca
     6421 atatctcgat tggaaaaccg gaagctacag atactgaaat catcgaagca gccaagctta
     6481 cccacagctg ggaatttatc cggaggcttc ctaaaggact ggacaccatg ctcaacgaag
     6541 acagcttaag ccagggacag aaacagctgc tgtgtatcac acgagttatg ctctgtctgc
     6601 ctccgatgct gatcctggat gaagccactt ccagtattga tacacgaaca gaattacaaa
     6661 ttcaggaagc gtttgaacga atgatggagg gaagaacaag ctttatcgta gctcacaggc
     6721 tttcaaccat ccgaaatgca gatctgattc ttgttatgaa agacggaagt atcattgagc
     6781 agggtactca tgatgagctg attgcaaaag gtggatttta ccatacttta tataacagcc
     6841 agtttgcaaa agtttctgaa taaaacaagc cagataataa atcaaaaagg aacagctgtc
     6901 catcacggct gttcctcttt ttgattttgt aaaatatttt tttattttta tcagattgct
     6961 cgggtagcat ctttcagcca ttctttttct tcttcgttca aatacggaga aatcttctca
     7021 tatacctgtg catggtaatc attgagaagg ttacgttccc gggcactcat cagttccggc
     7081 accactccat ccagatcaaa aggtaccata gttagaaatt caaaacacat aaactgacca
     7141 tactctgttt tttcagcttt tttgcagacc atcagatttt catgacggat tccaaatcca
     7201 tcctctctgt aatatcccgg ctcatcagag gtgatcattc cctcctccag cactgcattt
     7261 ccacccggaa caattttcca tcggaagcta ttgggtcctt catggacatt cagaagatat
     7321 cctactccat gaccggttcc atgtttaaaa ttctctccca tttcccatag cggctgtctc
     7381 gccagaatat ccagatttac accggtacag ccatgaagaa atctggcagc tcccagattc
     7441 agagttcccc gcaaaactgc tgtgaagtac tttttctctt cctcagtagt cggtcccatg
     7501 acaacagtac gggtaatatc agtagttccc tctttataat gtcctcctgt atctgccaga
     7561 agaaagccgg atggttccag aggaatatcc gtttcgggtg ttgcaaaata atgtacaata
     7621 gcagcatgct ttccataggc aataatcgga tcaaaactgt tatctatgaa atcctcctgt
     7681 tccgaacgga attcatacag cttttctgct gcacttaatt ctgtgatcgg aatccttcca
     7741 acattcttct ttaaccagta tatgaacttt gtaactgcaa ctccgtctct gatatgcgca
     7801 atgcgttcat tttccacctc aacaggattc ttcgttgcct tgggaagaag tgtaagattt
     7861 tcttcatcca gaatccgggt gtctgccgga atattgctaa ccagacgact gttgactttc
     7921 tttttgcaga gaagaacttt tttgtccttt ttaaatgttt tcacatactc atagataccg
     7981 tcatagggaa aaagggtcac accatctttt tccagcgctt ccagtacgtc tgtctgaaag
     8041 gctttctcat ttgcaaaaag tctgatctct gtttttgtca ttacaagata agaaagaacc
     8101 accggacaac agtggatatc tcccccacgt atatttaaca gccaggcaat atcatccaga
     8161 gaagtcagta caaataaatc tgcacccttc ttctccattg ctttgcggat tcttgcgcat
     8221 ttatcagctc tggattctcc tgcccatttt atatccagct ctgtaaccgg ttcacaggaa
     8281 agtaccggac ggttttccca tatatcgcct gccagatcgt gatcaacact gagagacaca
     8341 ccgttttcat ccagcatttt ctccaattct gctgcctctt ttgcactgac agtacgtccg
     8401 tcaaatccca gacaccttcc ctgtgtcaga ttttttttca gaaattcatg aactgtggga
     8461 acttccggtt cacccatttt aaataaagta attcctgttc cctccagctg atctgcagcc
     8521 tggataaaat aacgtccatc cgtccataat cctgccatat cctgcatgat caccgcagtg
     8581 cctgcagaac cggtaaatcc tgtgatatat tttctgcatt tgaaatattc acctacatat
     8641 tctgaaccat gaaaatcatc tgtaggaatc agatatgcat caattcctgt ttctttcatg
     8701 cgtgcacgaa gtgctgctat tctctctttt actgtcattc gtttttaccc ttaaggctgc
     8761 tatctgcagt cgttttatca ttttcgccaa gtgtttcgtt catacttccc atacgatatc
     8821 ccagaatatc catggtcaca taagtgaatc catactcctt aaatttcttt gcaatatcct
     8881 ctcggacatt tttttccaga agtttcggaa attcctccgg catgatctca attcttgcaa
     8941 gtgaaccgtg aatacggaca cgtacctgat ggaatccata gtcaagtaaa agctgctctg
     9001 ctttctcaac cattccaagc ttttcctcac tgatggtctc tccatagaca aacctggagg
     9061 acagacaggc aaatgactgt ttgtcccaag tcggaagccc cagttccttt gagtattctc
     9121 tgatctccgc tttcgtcagc ttcgcctcac atagcgggct cttaactcca agttctttta
     9181 cggcgatcag acctggtctg taatcgccgt tatcatccat atttgatccc tctgcaatat
     9241 attcaatccc attctttttt gcaatatcgc caatcttctc aaacagttct tttttacata
     9301 aataacatct gttcggagga ttctttgaaa atccttcaat ctccaattcc tcagactggc
     9361 agatcacatg ctgaatcccc tctttctcgc agaatgcctt cgcttcattc agctctcttt
     9421 tcgggaaaga acaggattga gccgtaatcg caatcgcctt atcacccagc acatcatgag
     9481 ctacttttaa taagaatgta gaatccactc cacttgagaa agcaactgct acactgccaa
     9541 gtcccttcag atattctttt aaatgttcta gtttattttc catatcagtc tgcctcttgt
     9601 ccgtttttta ttgtacctgt agcactcctc gtaaataatg tatattgatc tggctcaaca
     9661 aagcgtgaaa gttgaacttt ctcaaatgta ttatttaaca gggtgctata gcttcattat
     9721 aatataggca acgactgttc agcaacctat ttttcgcatt gcgaaatgtg ttactgaaaa
     9781 tagaacgaac aatattgatt tatgtttctt gtatcttttc taacgcttcc ccgacttcta
     9841 ttacttcttt aaatagtttc taaagtaaca gcctctctta acttctttat ttacagtttg
     9901 tctacttctt tttctgaagc agttctccgt ttgtttcttc tccattcata catgacataa
     9961 taattaacca ctaccccata ttataaataa cacccagaga tacttatttc agactgataa
    10021 tcagattttt attgaattta ttaatctata tgttatgaca acatatcttt cagacatgta
    10081 ctccggtagt cactcggtga tattttatat ctttctttaa atactcggtt aaatgttctc
    10141 tgactttcaa atccactatc cagacaaatg tttgtaatag aatcactcgt attttccaaa
    10201 cgatggcatg catagttcag ccttgcatcg ttaagatatt gattaaagtt tctatggaat
    10261 gttttggaaa agagtctgga taaaacatat ttgctcaccc ccagatcttt tgccatctct
    10321 tccagcgaaa atttcttctt aaaatttgct gatatatagg aaactgtctg gtaaataaga
    10381 tcgttgctcc ccacattact cttttctacc aaatttaatt ttcctatgca gcgtgccaac
    10441 acaatttgaa gatatgcctg tgcaacagta atatccgact gttctgtctc taaaattgca
    10501 tttataaccc tatatacctc cggttcaacc ttttcctctt tgatgattgg gtattcagga
    10561 gccatggat
//
