LOCUS       gnlProkkaPADNJICE_76   14488 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PADNJICE_76.
ACCESSION   gnlProkkaPADNJICE_76
VERSION     gnlProkkaPADNJICE_76
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 23:12:45
            Original ID  :: gnl|Prokka|PADNJICE_76
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 924
            Orig. end    :: 15412
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14488
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11281]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11281
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14488
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14488
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(14..1606)
                     /locus_tag="ctg76_2"
                     /transl_table=11
                     /translation="MMYQMGVYCRLSKDDGENKVSESIENQMKLIREYVTKSEDLEIAD
                     IYIDDGYSGLYFANRPEFQRMMEDIYKGKIQGVITKDISRLGREHIETSNYIERVFPSL
                     GVRYIAILDGVDSVHHSNEELAQFKTLFNDMYSRDISKKIRGALTAQKKRGQFMSGFAP
                     YGYVKDPADKHHFLVDEEAAKVVRRIFYMSLEGYSRDGIAKKLNQEGILTPSEYKRKVQ
                     GLKYANALEKAGAKGWAYPTINVILRNRVYTGAMVQHKSEKISYKVEKYQYIPEEQQYI
                     VEGMHEAIISKDTFEQVQELMKKRTRTPGFNSEVRKVNPYAGIIVCGDCGYNFQRVTCR
                     DGYECGTYHKKGNTVCYSHFIKKEVLDSIVKNEIQRQAELALKESDKDEILKVADRKKE
                     VQRRCAEADQQIERLQKELAAVQKYKKKTYENYVDGVLDKEEYLSYKAEYEKQDKDIRA
                     KIQLAEQEKDSFGEAEESYENWIEKFIKYGTLSEVTREIVTELIEKIVVNGDKSIDIVF
                     KYQSPYPVEKQAV"
     CDS             complement(1603..3192)
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="MYQAGIYCRISIEEQNKEGEYSNSIHSQIQMARDYIAENKDIAEK
                     KVYVDDGASGSNFERTEFRRMLADIELGVINMVIFKDVSRLGREHIDTNYYLGKYFPEK
                     QIRIVSILDNYDSAVGTYDEMLEIKTLLNDMYLRDTSRKIKTTIQTKRSMGEYTPKQPP
                     FGYVKSKTIHNHLEIDPYAAEVVRRIYRMYQNGFGCTVICRTLNEDEIPCPAKYKKEVL
                     KTNYVWDSGKGLWTSSTVSGILKNPVYTGAVVIRKHERPSYKLKYKKAIPLEEMELVPD
                     AHEAIISKEEFDRVQQIRKGRRVSYFDKNNEPHKYVGLLFCGKCKTAMRKRYLASHKDY
                     DGYMCGFHQKQGQNYCELNHITFEKLDELVVFAINQQLKQMKMDMKNLETQIRQKQPEL
                     DGKIAKLQAKIERNLEYRKRAYEQFMDEVLSKEEYLELKQMYETENQKYQKELSELNHE
                     EQRQRAAVNETKIWLEHFNRRRITVKQLTREALVELVDKIYVYPEQKIDIYFKFASVES
                     SPDRILEKDGVI"
     CDS             complement(3269..3436)
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MNTLFDSVEVLDTKKEIQKENVSYEHAGYQIRVHFNGEKTLIQCI
                     QNLTERKIAG"
     CDS             3714..6023
                     /locus_tag="ctg76_5"
                     /transl_table=11
                     /translation="MERCDFSSISTCLKNQISESNQMNQPDFLYELFEDFMNDPINEDF
                     SMDNGLICRWITGQAKISPKITSYYAKPSNQKKLATTIQRNLLPLMADCNMVIQDIYTL
                     FIQDDTISDTKKQELVSLYKPSDSRLLFLAKVLSFGMERQFIKRDTRNQKLIAGGVLSP
                     IVLDYIMDSEVPKPCRHFLGREEELDELHTLFEENRHIFLYGIAGIGKSELAKAYAKQY
                     RKQYTNILYMEYTGNLYQDIVDMDFIDDPPEISEQERFQRHNRFLRSLKSDTLLIIDNF
                     NVTSTQDSCLSVVLKYRCRVLFTTRSQLSEYCSFQLKELKDIPTLFQLTSVFYSEAEEN
                     RAIVEKIIETVHYHTFAVELAAKLLENGILTPEQLLIKLQEEKASLHNEDKIKVMKDGQ
                     SKKATYYNHIHTLFSLYSLSRKQQDIMCNMCFMPSSGISARIFSKWLELPTLNDVNDLI
                     ETGFVQSSLRHTISLHPMIQEIAVSETAPSVTSCHTLLDSLQKICLMHGIEVSYYKKLF
                     QTVENIMLFIEKDDIPQYLLFLEDVFPYMEKYHYQKGMKKIIQELQHFIKANTYGTASD
                     RALLLDYQATLEPKTEKAIKLEKEALAQIKETTKENAHLVSNLHSNLGGLYRINGQLDL
                     AKRHMKMGISLLQQYQLLYTNDSIPQINNYAVLLIEIQEPDLALSALQKLAQIIKEYNS
                     NHCLDYAQVQESLGSICLITANISQAKTHFKKALKIYEDIWADEPELIEEKYQAIQELY
                     PQAGIALAKSILLTKH"
     CDS             complement(6259..7116)
                     /locus_tag="ctg76_6"
                     /transl_table=11
                     /translation="MRENGKTWYRICKMLCEYKKYFPGIICCLLGSSFITFIHPLLIRQ
                     ITDCGILQKNMKYILLFSVILIIISLTQQELNIIQTKLFSNVHNQFTHSLYKKTYWKIN
                     RMKIQYFAERGSAEIINTIGMDIDNVSSVVDQITQFSISSILQIIGGVVGLSLLDWKLA
                     ILIEAIIPLKFIIVSYCANKKREVFEQWIEDKRKFMSWFAECINGIHEMKLWNLFQVKK
                     SQFEGLQKDLMDSYKKNAMLDEYSTVSVVVIDTVVNALLYILSGLFIIKGEFTIGGAFA
                     FITY"
     CDS             complement(7142..8236)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075:alkaline serine protease, subtilase family
                     (Score: 53.3; E-value: 4.5e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_7"
                     /transl_table=11
                     /translation="MIKLALIDNGIPYHMRNNRNQRIVHKSFLASKCDPSEYKDDKSFH
                     GAVCVGIITSICSDIELWDLNVTDSAGTTQITVLLEALEWCIQNKIKLIHMSLGTINYF
                     DIKPLWIQIKRLLDADAIIVAAYHNRNIKTYPAAYPGVFGVRQDRYGLLGNGQILFQEQ
                     KGYNIENSIIANFSWNGIVNQANSYAAPVVTGHIATYLNRKPTAGFDDVMDFLMTIATH
                     KSDYPDILENVIRDKTNIEIPVIAGIDLDYEEMIQLKVMFSQNGYYAINLQKNPLDENV
                     IPLEYYDDSNESLNDILYTVYIAYEPDIILLNQEEEIFESSKASDIDMYIVRKNNMYEL
                     YAEDRIGITYNIEDIYELVCQYFA"
     CDS             complement(8352..9872)
                     /locus_tag="ctg76_8"
                     /transl_table=11
                     /translation="MKKSVLAIMVGALCIILSSCQETPEESSVVSKVDGISEAAVCEPL
                     KKGEKRETNVPTHWKFEEKKSNDRVVIQADIKLGEQSIGNLPVIEMQNHELTQEELNGL
                     IDYFTDGEELYMPQMVTKDAYQEVLDRISSKEGSYLQSAYSTSIAGIQNATREGMELAP
                     DEASAPEKMEIKFQKKTEDHGVEAARSWMSTELENTDTEDYFTADVGEDRKAYIEAERY
                     NQEIDNDSSFLWMEGSNFIEEETIETEEMQSEYYSSFGMDTNGYTEKFHELADAYRKCM
                     DKITFTEEDGKEQAEQVLEDLGIDGMGLVDSDRTVWFPNGACSERNGLGLGSDALWQGD
                     LDRGLPGYLYCFSKSVEGITSVPDGVVAEETVDSYVPPFQVETISILITEEGIKYFKWD
                     GISEEVCTVTENTKLLPFEKIQAKLTDQIFYWYSGKGQSANDTTALEYDVVNAKLQYTY
                     TTAYQEPKHAWLVPAWIFTVRESIGGNSLQELSYVINAYDGSVIGEAY"
     CDS             complement(10001..11281)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_9"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     1.7e-14, bitscore: 43.8, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.1e-16, bitscore: 51.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.4e-14, bitscore: 42.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKVLIKCIQTPMQKYFYDRSLDSVVMVNDEEYQILKTVEKTKLV
                     PDGVLRRFVKSGLLRETAIEEIEHPETENLHLLAEHYMGNLILQVTQQCNLRCKYCAYS
                     GNYYNRSHTSNRMDFETAKKAIDFYLKRSEKADQLALSFYGGEPLLEFELIKKCVSYIL
                     QRKGDKKILFTMTTNGTLMTEDVIEFLVKYEFNLMISLDGDKKSHDINRRFKTGKGSFD
                     IILENLSRLKAYNEEYYSKVLFNCVISSSSDLENIYRFYSEEELFEAGTVNFNYVNPVG
                     LKDETLSRITQKNFRVHRLAYIKMILSVLEKRKWDAQSRLLRRELQDIELLYEQLHSHV
                     AEGKKTHHGGPCIPAVRRLFVDTKGEFFPCERVSEEDSEMCIGSLDSGFDFDKMSFLLN
                     HGKMIKEKCLGCWNLRMCAYCLAQIPK"
     CDS             complement(11300..11941)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 165.4; E-value:
                     2.9e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg76_10"
                     /transl_table=11
                     /translation="MEYAIRLKGLTKSFQKEKVLKNITHDFEKGKIHGIMGFNGSGKTV
                     MFKCICGFLQPESGTVLVGGKQIGKELDFPDSVGIIIENPGFFLDLSGFANLKRLASLK
                     HRISDDDVRATMRALGLDPLSKKKVGQYSLGMRERLGIAQAIMEDPELLILDEPFNGLD
                     KQGAGEVCELLRGLKERGKTILIAAHNMLEIEWLCDTICEMDAGVLTQIK"
     CDS             complement(11954..12847)
                     /locus_tag="ctg76_11"
                     /transl_table=11
                     /translation="MRDIKQAFWIAGQNFYGWKKSPRIWMTFILAAILCLMLSDQIISH
                     AIKYETILQVFEPFIWTYGDASSVMLSSLLLILLFADMPFISQATPYWLVRTKRKIWLA
                     GQIIYVILATVIYNIFLAVMLGIMGAPFSFTGNVWSETAAMLGYGGGESITVPVSIKTM
                     ESSTPYMCAAIVFGLVLLYTLFIAVLMLFLNLAAGNMAGVIGAFAVSLYGLLLNPDVFR
                     KLFHFTESQEYRANVFCGWLSPLNQATFPMHSFGYDYLPGIGMSMFIFAILIIALIGLS
                     AVRIKGYNFSFTQTNE"
     CDS             complement(12840..13595)
                     /locus_tag="ctg76_12"
                     /transl_table=11
                     /translation="MRNVLATDIKNNIRSIRFILGIFLIVSATLMSEHEMLQKIINAGG
                     SAEGPGWFVAYTYCMNSVNMLLFVPIAVAFAGGENTEAELHSRFFLFSYIRSGRKQYLV
                     GKAAGLLVSGGLTAFLAMVFLLVICILRFGQYPSLIDGNYEMAVLVGRTAVSFLRLFLN
                     GAFWALIGGTSAVITKNRYMSYAVPFILYYVLTVFQERYYQKAFFLSPRYWAASIYYND
                     IFCIAILAVGSFLTALIFMCAIERRLRYA"
     CDS             14133..14486
                     /locus_tag="ctg76_13"
                     /transl_table=11
                     /translation="MRELRNTKIIAVDHGYGNMKTANTVTPTGIKAYETEPIFTGNILE
                     YNGIYYRIGEGHKEFIPDKAMDEEYYLLTLMAIARELNVFSIREADVHLAAGLPLTWIR
                     NQREDFRSYLLQNP"
ORIGIN
        1 aaatttgcag tctttacact gcctgttttt ctaccggata aggcgactga tacttaaata
       61 caatatcaat gctcttatct ccattcacaa caattttttc aatcaattct gtcacaattt
      121 ctcttgtcac ttcggataat gttccatact tgataaattt ctctatccag ttttcataag
      181 attcttctgc ctctccaaag ctgtctttct cttgttctgc caactgaatc ttcgccctga
      241 tatctttatc ctgcttttca tattctgcct tataggagag atattcttct ttatccagaa
      301 caccatctac ataattttcg taagttttct ttttatactt ttggacagcc gcaagttctt
      361 tttgtaaccg ttcaatctgc tggtctgctt ctgcacatcg tctctgcacc tccttcttcc
      421 tatctgctac ttttaatatt tcatccttat cactttcttt cagtgccagt tccgcttgtc
      481 tttggatttc attttttaca atagaatcca atacttcttt tttaatgaaa tgagaataac
      541 aaactgtgtt tccttttttg tgataggtac cgcactcata accgtcccga caagtaaccc
      601 tctggaaatt atatccgcaa tctccacaaa caataattcc tgcgtatgga tttacctttc
      661 tcacttcgct attaaatccc ggtgtccgtg ttcttttctt cataagttcc tgtacctgct
      721 caaaagtatc tttgctaata attgcttcgt gcattccttc cacaatatac tgctgttcct
      781 ctggaatata ttgatacttt tccactttat aggatatctt ttctgattta tgctgtacca
      841 tagcccctgt ataaactctg tttcgcaaaa ttacattgat cgtaggatat gcccagccct
      901 ttgcacccgc tttttctaat gcattggcat atttcaatcc ctgcaccttt ctcttatact
      961 ctgacggtgt cagaattcct tcctgattca gtttctttgc aataccatcc ctggaatatc
     1021 cttccaaact catataaaag attctccgta ccactttagc tgcttcttca tctacaagaa
     1081 aatgatgctt atctgccgga tcttttacat atccatatgg ggcaaaccca gacataaact
     1141 gtccccgttt cttctgggcg gtcaatgcac ctctgatttt cttagatata tcacgactat
     1201 acatatcatt aaacaacgtc ttaaactgtg ccaattcttc attactgtga tgaacagaat
     1261 ccacgccatc caaaattgca atataacgca cacccaaaga tggaaaaaca cgctcaatat
     1321 agttactggt ttcaatatgt tcacgcccaa gccgggaaat atctttcgta ataacgcctt
     1381 gaattttccc tttgtagata tcctccatca tccgctgaaa ttccggtcta ttcgcaaaat
     1441 aaagccccga ataaccgtca tcaatataaa tatctgcgat ttccagatcc tctgatttag
     1501 tcacatactc acgaatcagt ttcatctgat tttcaatact ctcactaact ttattctctc
     1561 catcatcctt cgacagacga caatatacac ccatctgata catcatatca ccccatcttt
     1621 ctcaagtatt ctatctggtg aactctctac tgaagcaaac ttaaaatata tatctatttt
     1681 ctgctctgga tatacataaa ttttatcaac taactccaca agcgcttctc tggtaagctg
     1741 ctttaccgtt attcttctgc gattaaagtg ctccaaccat atctttgttt cattgaccgc
     1801 cgcccgctgc ctttgctctt catggttcag ttctgataat tctttttgat atttctgatt
     1861 ctctgtttca tacatctgtt ttaattccag atattcctct ttggaaagta cttcatccat
     1921 aaactgttca tatgctcgtt tccggtattc cagatttctt tctatttttg cctgcaattt
     1981 tgcaatttta ccatccagtt ccggctgttt ctgtctgatc tgagtttcca gattcttcat
     2041 atccatcttc atctgtttca attgctggtt gattgcaaat acaaccagtt catccagctt
     2101 ttcaaatgta atatgattca gctcacagta attctgcccc tgcttctgat gaaaaccaca
     2161 catatatccg tcatagtctt tatgagatgc cagataacgt tttcgcatgg ctgttttaca
     2221 tttcccacaa aagagcagtc ccacatattt atgtggttca ttgtttttat caaaatagga
     2281 aactctgcgc ccctttctta tttgctgaac cctatcaaac tcttctttag aaatgattgc
     2341 ctcatgtgca tccggcacca gctccatttc ttccagggga attgcctttt tgtatttcag
     2401 cttataagac ggtctttcat gtttccgaat cacaaccgcc ccagtataga ccggattctt
     2461 taaaattcca cttacagtag acgatgtcca cagacctttt cccgaatccc atacataatt
     2521 ggtttttaaa acttcctttt tatattttgc gggacaaggg atttcatctt cattcaaagt
     2581 cctgcaaata accgtacagc caaatccatt ttgatacatt ctgtaaattc ttcgaacaac
     2641 ctcggctgca taaggatcaa tttccagatg attatgaatt gttttacttt tcacatatcc
     2701 aaaggggggc tgtttcggag tatattcgcc catacttctt ttggtctgaa tcgttgtctt
     2761 aatctttctg gatgtatctc tcaaatacat atcattcagc aaagttttta tttctaacat
     2821 ttcatcataa gttccaacgg ctgaatcata attatccaga atcgaaacaa tccgaatctg
     2881 tttctccggg aaatatttgc ctagataata gttggtatca atatgttctc ttccaagtcg
     2941 agatacgtcc ttaaaaatca ccatattgat aacaccaagc tcaatatctg ccagcatcct
     3001 ccgaaattca gttctttcaa aattacttcc agaagcccca tcgtctacat aaactttttt
     3061 ctctgcaata tctttattct ctgcaatata atctcttgcc atctgaatct gagagtgaat
     3121 actattgctg tattcaccct ctttattttg ctcttcaatg gaaattcggc aataaattcc
     3181 tgcctgatac attctatccc tcttttcatc ggtcttgcgt agtcattgtc tttaattgtc
     3241 tttattttac aacaagaact taagaaaatc aacctgcaat ttttcgttca gtaagattct
     3301 gaatgcactg gatcaatgtc ttttccccat taaaatgcac tcgaatctga tatcctgcat
     3361 gttcatagct tacattctct ttttggattt ctttttttgt atccagaact tctacagaat
     3421 caaataacgt attcatgcta tatgcctcct tcagcataca gttctctcta catcctatgc
     3481 cggcaggatt gtacaaaagt tctgtatgaa ttgaattcgg ctttcgaaag cctgattaca
     3541 ttctaaaatt attctgcacc aatcacattg aattgaaatt gaccgcagat tgagttttta
     3601 agattcattt tcttcctata cagtatcaat tcctattgtc cggaacattt gttcgtgtta
     3661 taataaaaag actttaagaa tataaaacac gaaaaccaaa ggagggattt ctgttggaac
     3721 gatgtgattt ttcttctatt agcacatgcc taaaaaatca aatcagtgaa agcaatcaga
     3781 tgaaccaacc tgatttttta tacgaattat ttgaagattt tatgaatgat ccgataaatg
     3841 aagatttttc tatggataat ggtctaattt gccgctggat aaccggacaa gcaaaaatca
     3901 gtcccaaaat aacctcatat tatgcaaaac ccagcaatca gaaaaaactg gcaacaacca
     3961 ttcagcggaa cttacttccc ttaatggcag actgcaacat ggttatacag gacatttaca
     4021 cgttattcat acaggacgat acgatttcgg atacaaaaaa gcaggaactt gtatctctat
     4081 ataaaccttc tgattcaagg ctgttgtttt tagcaaaagt actttctttt ggtatggaac
     4141 ggcaatttat taaacgtgat acaagaaatc aaaaactgat tgcaggaggt gttctatctc
     4201 cgattgttct ggattacatt atggacagcg aagtcccaaa accatgccgt cattttctag
     4261 gaagagaaga agaactggat gaactccata ctttgtttga agagaaccga catatatttc
     4321 tttatggaat tgccggaatt ggaaaaagcg agcttgctaa agcctatgca aagcaataca
     4381 gaaaacagta caccaatatt ctctatatgg aatacaccgg taatctatat caagatattg
     4441 tagacatgga ttttattgat gatccaccag aaatcagtga gcaggaacgt tttcaaagac
     4501 ataaccgttt cttacgctct ttgaaatctg atacactgct gatcatagac aattttaatg
     4561 tcacatccac acaggacagt tgcctgtcag tcgtattaaa ataccgttgc cgggttttat
     4621 ttacaaccag aagccaactg tctgaatact gtagttttca attaaaagaa ctgaaagata
     4681 tacccactct ttttcaactg acatctgtat tttattcaga agcagaggaa aaccgggcaa
     4741 tcgtagaaaa aatcatagaa actgtacact accatacttt tgctgtcgaa ctggcagcca
     4801 aacttctgga aaatggaatt ttaactccag agcaattatt gataaaactt caagaggaaa
     4861 aggcttctct tcataatgaa gataagatta aagtaatgaa agatggtcag agcaaaaaag
     4921 ccacctatta caaccatatc cataccctgt tttcgttata ctccttatca cggaaacagc
     4981 aggatattat gtgcaatatg tgttttatgc cttcatctgg tatttctgcc cgtatatttt
     5041 ccaaatggct ggagctgcct actttaaatg acgtgaatga tctgatcgag acaggttttg
     5101 tacagtcaag tctccggcat actatttctc tgcatccaat gattcaggaa attgcagttt
     5161 ccgagaccgc accttctgtt acaagctgcc acacgttatt ggattctctg caaaaaatat
     5221 gtttgatgca tggcattgaa gttagctatt ataaaaaatt atttcaaaca gtagaaaaca
     5281 tcatgctttt cattgaaaag gacgatattc cccaatacct gttattttta gaagatgttt
     5341 ttccatatat ggagaagtac cactatcaaa agggtatgaa aaaaatcatc caggaactac
     5401 agcattttat aaaagcaaat acttacggga ctgcatctga ccgtgcctta ctattggatt
     5461 atcaggcaac tctggaaccc aaaacagaaa aagcgataaa attagaaaaa gaagcacttg
     5521 ctcaaataaa agaaaccaca aaagaaaatg cccacctggt ttccaacctc cattccaatc
     5581 ttggagggct ttaccgaatc aacggacaac ttgatctcgc taaaaggcac atgaaaatgg
     5641 gtatctctct tttacaacaa taccagcttc tttatactaa tgacagtatt cctcagatta
     5701 ataattatgc tgtcctctta attgaaatac aagaacctga ccttgccctg tctgctcttc
     5761 agaaattagc acagattatc aaagaatata attcaaacca ctgtttggat tatgcccagg
     5821 tacaggaatc ccttggaagt atctgcctga tcactgcaaa tatttcgcaa gcgaaaaccc
     5881 attttaaaaa agccttgaaa atttatgagg atatatgggc agacgaaccc gaattgattg
     5941 aagaaaaata tcaagcaatt caagaattgt atccacaagc tggaattgct ctggcaaaaa
     6001 gtattcttct caccaagcac taacggttcc tacaaacact tgtaaaatat attgcctcaa
     6061 taatgtaaac gcctagtttt gagatacact ccaagactag gcgcttgtcc atttccattt
     6121 tttcttagac atggagcnnn nnnnnnntca cttttctttt tttgacactt ttcgctcctc
     6181 ctatctcaaa ttttttatag tctaggtata ttgccttcat caatgcctga gaacttgtaa
     6241 atatgctcct ctgcttgttc aatatgtaat aaaagcaaat gctccgccta tagtgaattc
     6301 tccttttatt ataaaaagcc cacttaatat atataataac gcatttacaa ccgtgtctat
     6361 tactacaaca ctgacagtac tatattcatc tagcattgcg ttctttttat atgaatccat
     6421 caaatctttt tgcagacctt caaattgaga tttttttacc tgaaacagat tccagagctt
     6481 catttcatga attccattta tacactcggc aaaccaactc ataaactttc gtttatcctc
     6541 aatccactgt tcaaacactt cccgtttctt gtttgcacaa taggacacta ttataaattt
     6601 cagtggaata attgcttcta tcaatattgc taatttccag tctaataagg acagcccaac
     6661 tactcctcct attatttgga gaattgatga tatagaaaac tgagtaatct gatccacaac
     6721 agatgacaca ttatcaatat ccataccaat tgtatttata atctctgcac ttcctctttc
     6781 agcaaaatac tgtattttca tcctattgat tttccagtaa gtctttttat agagagaatg
     6841 tgtaaactga ttatgtacat ttgaaaataa ttttgtttgg attatattta actcttgctg
     6901 ggttaaagaa attattatta atataacaga aaataaaaga atgtatttca tgtttttctg
     6961 caatatacca caatctgtta tttgtcttat aagcagtggg tgtataaacg ttatgaatga
     7021 tgaacccaaa aggcaacaga taatccctgg aaaatacttt ttatattcac acaacatttt
     7081 acaaattcga taccatgttt tcccattttc tctcatatcc aattgccatc ctcactattc
     7141 gttaagcaaa atattgacaa acaagctcat atatatcctc tatattgtaa gttattccta
     7201 ttcgatcttc tgcatacaat tcatacatat tatttttacg cacaatatac atatctatat
     7261 ctgatgcctt actactttca aatatttctt cctcttgatt caaaagaata atatcaggtt
     7321 cataagctat atatactgta taaaggatat cgttcaatga ctcattggaa tcgtcataat
     7381 attctaaagg aattacattt tcatctaaag gatttttctg cagatttatt gcgtaataac
     7441 cgttctgact aaacatcact tttagctgta tcatttcctc gtaatctaaa tcaataccgg
     7501 caattaccgg tatctctata ttggttttat cccttattac attttctagt atatccggat
     7561 aatcagattt atgcgttgct atagtcatca aaaagtccat aacatcatca aatcctgctg
     7621 tgggctttct gtttaaatat gtagcaatat gtccagtgac aacaggagcc gcataactat
     7681 tggcttgatt tacgatccca ttccacgaaa aatttgctat aatagaattc tcaatattat
     7741 aacctttttg ttcttgaaac agaatttgac catttcccaa aagaccataa cgatcctgcc
     7801 tgacaccaaa aacacctgga tatgcagctg gataagtctt tatatttctg ttatgatatg
     7861 ctgctactat aatcgcatca gcatcaagta atctttttat ttgaatccat aagggtttaa
     7921 tatcaaaata attgattgtt ccaagactca tgtgaattaa ctttatttta ttttgaatac
     7981 accattccaa agcttccagc aaaactgtga tctgtgttgt tcctgcagag tcagtcacat
     8041 tcaagtccca taattctata tcactacata tgcttgtgat aattccgacg catacagcgc
     8101 catggaatga tttatcgtct ttatactcac ttggatcgca tttagaagcc aaaaaagatt
     8161 tatgaacaat cctttgattc ctgttatttc tcatatgata aggtataccg ttatcaatca
     8221 atgcgagctt aatcatttgc actattccta ttcttacctg ttatatatcc aagccaaata
     8281 tcgcatattt attattctca tgataaacct tgtaattcta tggtcaataa aaattcaagt
     8341 gtcgctgaac cctaatatgc ttctccaatc acactgccat cataagcatt gatcacataa
     8401 gaaagctcct gtagagaatt tccaccaata ctttccctga cagtaaaaat ccatgctgga
     8461 accaaccatg cgtgtttcgg ctcctgatag gctgtggtat aagtatactg caattttgcg
     8521 tttaccacat catactccag tgcggtagtg tcgttggcag actggccttt tccggaatac
     8581 caataaaaaa tctgatctgt cagctttgcc tgtatttttt caaaaggcag aagctttgta
     8641 ttttccgtca ccgtacagac ttcttccgat atcccatccc atttaaaata tttaattcct
     8701 tcctctgtta tcagaataga gattgtttct acctggaacg gaggcacata actatccact
     8761 gtttcttccg caaccacgcc atcaggaact gaagtaatac cctctacact tttcgaaaaa
     8821 caatacagat atcccggtaa tcctctatcc agatctccct gccacaaagc atcactacca
     8881 agtcccagac cattgcgctc tgaacatgcg ccattcggga accacacggt acgatcagaa
     8941 tctacaaggc ccattccatc gatacctaaa tcctctaaaa cttgttctgc ctgttccttt
     9001 ccatcttcct ctgtaaaggt gatcttgtcc atgcactttc gatacgcatc tgccagttca
     9061 tgaaatttct ctgtatagcc gttggtatcc atgccaaagc tactgtaata ctcactctgc
     9121 atttcctcag tttctattgt ttcttcttct ataaaattag aaccctccat ccagagaaaa
     9181 ctactgtcat tgtcaatttc ctgattatac cgctctgctt ctatatatgc cttcctgtcc
     9241 tcgcccacat ctgcagtaaa ataatcctct gtatctgtgt tttccaattc agtactcatc
     9301 caactccgtg ccgcttccac accgtgatcc tctgtttttt tttgaaattt tatctccatc
     9361 ttttccggtg cagacgcttc atccggtgca agctccatcc cctctcgggt tgcgttttga
     9421 atccctgcaa tcgatgtaga atatgctgat tgcaagtaac ttccttcctt gctggaaatc
     9481 ctgtctaaca cttcctgata cgcatccttt gtcaccatct gtggcatata tagttcctca
     9541 ccgtccgtaa aataatcaat caatccattc agttcttcct gcgttaactc gtgattttgc
     9601 atctctatga ctggaagatt gccaatgctt tgttcgccca acttaatatc tgcctggata
     9661 accacacggt cgttgctttt cttttcttca aatttccaat gcgttggaac atttgtctct
     9721 ctcttttctc cttttttaag aggttcacag acagccgcct cgctaatccc atccactttg
     9781 ctgactaccg aactctcctc tggtgtttcc tgacagctgg aaagaataat acacaacgca
     9841 cctaccataa ttgctagaac actttttttc atttttcctc catatatctt atagaattgt
     9901 cgctttttca cgaaacttca attataaact ctttaactta taaatacctt cctgacacta
     9961 ttaacgtttt cgtatatttt ttagaaacag actaccttat ttattttgga atttgcgcca
    10021 aacaatatgc acacattctc aaattccaac atcctaaaca tttttcttta atcatcttac
    10081 catggttaag taggaaactc attttatcaa aatcaaatcc cgaatccaaa cttccgatgc
    10141 acatttctga atcttcttcc gaaactcttt cacatggaaa aaattcacct tttgtatcca
    10201 caaatagtct tctaactgca ggaatgcatg gaccaccatg atgtgttttt ttgccttcag
    10261 caacatgact atgtagctgt tcatataata actcaatatc ttgcagttct cttcgcaaca
    10321 atcgactttg tgcatcccat tttcgcttct ctaatacaga taaaatcatc tttatatatg
    10381 ctagtcgatg tactctgaaa tttttttgtg ttatgcgcga caatgtctca tcttttaaac
    10441 caactggatt tacataattg aaattcactg tccctgcttc aaacagctct tcttccgaat
    10501 aaaatcgata tatattttca agatctgatg aagaactaat aacacaatta aacaaaactt
    10561 ttgaatagta ctcttcattg taagctttca gtctactcaa attttctaaa ataatgtcaa
    10621 atgaaccttt tcctgtttta aatcttcgat ttatatcgtg acttttctta tcaccatcaa
    10681 ggctaatcat aagattaaac tcatatttta ccaaaaattc tatgacatct tctgtcatta
    10741 aagtcccatt agtcgtcata gtaaaaagaa tttttttatc ccctttacgt tgtaaaatat
    10801 aggaaacaca tttcttaatc aattcaaatt ccagaagagg ctcaccccca taaaatgata
    10861 atgcaagttg atccgctttt tcgcttcttt tcaaataaaa gtctattgct tttttggctg
    10921 tctcgaaatc catcctattt gacgtatggg aacgattata gtagtttcca gaatatgcac
    10981 aatatttgca tctcaaatta cactgctgag ttacctgcaa aatcagattg cccatataat
    11041 gttctgccaa caaatgtaag ttttctgtct caggatgctc aatttcttct atcgcagtct
    11101 cacgcaataa tccgcttttc acaaaccgtc ttaacactcc atcaggaacc aattttgtct
    11161 tttccacagt ttttaatatc tgatattctt catcattcac cataactaca gaatccaaag
    11221 aacgatcata aaaatatttc tgcattggtg tttgaatgca tttaattaat acctttccca
    11281 tattctttcc cccgtatttt tattttatct gcgtcaggac acctgcatcc atctcacaga
    11341 tcgtatcgca gagccattcg atctccagca tgttatgtgc tgcgataaga atagtcttcc
    11401 ctcgttcctt taatccccgc aaaagctcgc agacctctcc tgccccctgc ttgtccagac
    11461 cattaaaagg ctcgtccaat atcaaaagct ccggatcttc catgattgcc tgtgcgatac
    11521 caagacgttc acgcattcca agagaatact gtcctacctt ctttttagac agaggatcaa
    11581 gccctagggc acgcatcgtc gccctcacat cgtcatcgga aatacggtgt ttcagagacg
    11641 ccagtctctt taaattcgca aaaccgctga gatccagaaa gaagccaggg ttttcaatga
    11701 taatgcctac ggaatctgga aagtccagct ccttcccgat ctgttttccc cctacgagca
    11761 ctgtgccgct ctcaggttgt aaaaatccac agatgcattt aaacattacg gttttccctg
    11821 aaccgttaaa ccccataatc ccatgaatct tccctttttc aaaatcatgg gtaatgttct
    11881 ttaatacttt ttctttttga aaggattttg tcagtccctt caacctgatt gcatattcca
    11941 ttttgccctc catttattcg tttgtctgcg taaaagagaa attatagccc ttaattcgga
    12001 cggctgacaa gccgatcagc gctatgatta atattgcaaa tatgaacatg ctcatcccga
    12061 tccctggcag gtaatcataa ccaaagctgt gcatgggaaa ggtagcttgg ttcaacggag
    12121 acagccagcc gcagaacacg ttcgccctat attcctgact ttctgtaaaa tgaaacagtt
    12181 tccggaaaac atctgggttc agcaggagcc catacagact gactgcaaaa gcaccgatca
    12241 cccctgccat atttcccgca gccagattta aaaacaacat gagaactgcg ataaaaagag
    12301 tatataaaag tacaagtcca aacactattg ctgcgcacat ataaggagtt gagctttcca
    12361 ttgtttttat ggaaacagga acggttatgc tctccccacc gccatagccc aacattgccg
    12421 ctgtttcgct ccacacattt cccgtaaagg aaaagggagc tcccataatt ccaagcatca
    12481 cagccaaaaa aatattatag atcacagtcg ccaggatcac atagataatc tgacccgcaa
    12541 gccatatctt ccgttttgtg cgtacaagcc aatacggagt tgcctgactg ataaatggca
    12601 tgtccgcaaa gagcaggatt aaaagcaggg aggacagcat aacagaggat gcatccccat
    12661 atgtccaaat aaacggctcg aatacctgaa ggattgtctc atattttatc gcatgggaaa
    12721 taatctgatc cgacagcatc agacataata tagctgccaa aataaaggtc atccagatcc
    12781 tcggactttt tttccatcca tagaaattct ggcctgcaat ccaaaaagcc tgtttaatat
    12841 cacgcatacc gcaaccttct ttctattgcg cacataaaga tcagtgccgt taaaaaactt
    12901 ccaaccgcta atatagcaat gcagaagata tcattgtagt aaatagacgc cgcccaatag
    12961 cggggactca gaaagaatgc tttttgatag taacgctcct gaaatacggt caggacataa
    13021 taaagaataa aaggaacggc ataggacata tagcgatttt ttgttatgac agccgacgta
    13081 ccgccaatta gcgcccaaaa agcgccattt aaaaacaatc tcagaaagct taccgccgtt
    13141 ctgcccacaa gcactgccat ctcataattt ccgtcaatca gagaaggata ctgaccgaac
    13201 ctcagtatac agattacaag aaggaacacc atggctaaaa aagctgtcaa acctccggag
    13261 accaacaatc ctgctgcttt tcctacgaga tactgttttc tccctgaacg gatataactg
    13321 aacagaaaaa aacgactgtg cagctcagcc tccgtattct ctccacccgc aaaagcaacg
    13381 gcaatgggaa caaacagaag catattaacg ctgttcatac aataggtgta tgctacgaac
    13441 cagcctggtc cttctgcaga tccgcctgca tttatgatct tctgcaacat ctcatgctca
    13501 gacatcaggg tagccgaaac gattagaaaa atccccaaaa taaagcgaat gcttcgaata
    13561 ttgtttttta tgtccgttgc caacacattt ctcatacgct tttctcctca cttcaaacag
    13621 ctatagactt gattttttta tttttataaa atcctagttt tttgcaataa tatcactatt
    13681 tgtataaaac tacactcctt atcaaacaac agttaaggac ttgcaaaaac tgttgttcct
    13741 actgaaagca ttgcaacagc tgtaaaaatt gataatattt taaattttct attattctaa
    13801 gttctacaaa tacataagcc gccagttaag tacgattagt tttattataa ttcaataaat
    13861 tccatccaac tttccacatt ttattgtgca attttaccat ttatataata acatgtcaac
    13921 atttaatgaa cgtttataac aaaaaaatgc agggctataa aaaactaaag aaattgctct
    13981 attttacaaa attatatcct atttttcaat tccaactcaa ttttccctca atgtcttttt
    14041 cctccaactt tcgtatgctt atctcacagc aaagcagtac cacaccggta cagcctgctg
    14101 aattaatcaa tacgaaaatg gaggtgtttt ttatgcgaga actcagaaac acaaaaatca
    14161 ttgctgtaga tcacggctac ggcaacatga aaacagcaaa taccgtcaca ccaaccggaa
    14221 tcaaagccta tgaaaccgaa ccaatcttca ccgggaatat tctggaatat aacggcattt
    14281 actaccggat tggcgaagga cacaaagaat ttatcccgga taaagctatg gacgaagaat
    14341 attatcttct gactctcatg gctattgcaa gggaactgaa tgtcttttcc atccgtgaag
    14401 cagacgttca tctggctgcc gggcttcctc tgacatggat cagaaaccag agagaagatt
    14461 tccgttccta tctgctccag aatccaga
//
