LOCUS       gnlProkkaEJHMKEPD_27   12776 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EJHMKEPD_27.
ACCESSION   gnlProkkaEJHMKEPD_27
VERSION     gnlProkkaEJHMKEPD_27
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 17:22:47
            Original ID  :: gnl|Prokka|EJHMKEPD_27
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12776
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12776
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[3462:7776]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3463..7776
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..12776
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12776
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..2240
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.5;
                     E-value: 6.3e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg27_1"
                     /sec_met_domain="Poly_export (E-value: 5.2e-18, bitscore:
                     57.1, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLE
                     DHPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTI
                     RQQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGN
                     IRTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDV
                     YEFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGG
                     FEADAYTRSLRVVRQNGEEYEVNTVKDIDYSIYKMRNGDVVTAEAILNRFTNKLEIRGA
                     VYRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDG
                     TSPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKE
                     AASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSP
                     GYQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEK
                     KRMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISI
                     PKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVK
                     GSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             2251..3399
                     /locus_tag="ctg27_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             3463..4182
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.5e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             4203..5504
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1e-12, bitscore:
                     40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             5521..6645
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.7e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             6655..7776
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg27_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.1e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        6745..7752
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg27_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg27_6_Aminotran_5.1"
                     /locus_tag="ctg27_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             7773..7916
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             8119..9603
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_8"
                     /sec_met_domain="Polysacc_synt (E-value: 7.2e-31, bitscore:
                     99.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYY
                     TNSLIDLTLKLQVKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLS
                     FLFKLDSFFCILTLIIKTKNIDENIKKDFSSNSKDN"
     CDS             9557..10816
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNKPVIF
                     NFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLM
                     NQFQDDNSTKRICDIFLNEI"
     CDS             10825..11574
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             11574..12614
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 ccaaagaaca ggcaatgcgt gtgaagcagc tatacgagca gcagaacaat gtaaatacct
       61 cgaaatcaac gggcacggac atcaacgaat cccgcctgcg tgaagagact aagaagaata
      121 cttccgatat gctggaggat catccgacta ctcaggacct tgcccgtggt gatcaggtct
      181 tcggacgtaa catcttcaat acccgcaacc tgacgttcga gcctagtgtc aaccttgcca
      241 ctcctgccaa ttaccgtctt ggtcccggtg atgaagtcat cattgatatc tggggtgcga
      301 gccagaacac gatccgccag caaatctctc ctgaaggtac tatcaacatt cagaagatcg
      361 gccctgtcaa ccttagcggt atgacagtct ctgccgccaa tgactatctg aagaacgccc
      421 tgaataaaat atataacggt ctgaataata ctaccgatcc tacttccgac atccgtctga
      481 cgttaggtaa tatccgtact attcagatta atgtgatggg agaagtcgta cagcccggta
      541 cctacgccct ttcttccttc tctaccgtct tccatgcgct ttatcgtgca ggcggtgtga
      601 gtgatatcgg tagcctccga aacgttcagt tggtacgcaa cggaaagaat attgccacca
      661 tcgacgtcta cgaattcatt atgaaaggca acacacagga tgacatccgc ctacaggaag
      721 gtgacgttgt gattgttcct gcctatgatg tattggtaaa gattagcggc aaggtaaaac
      781 gtcctatgcg ttttgaaatg aagaaagacg agaaccttgc tactctcatt aaatatgccg
      841 gcggctttga agccgatgcc tacacccgtt cattacgtgt tgtccgtcag aatggtgagg
      901 aatacgaagt caacacagtc aaagatatag attacagcat ttataaaatg cgtaacggcg
      961 atgttgtaac agccgaagcc atccttaacc gcttcacaaa caaactggaa atccgtggcg
     1021 ctgtctatcg tcccggtatc taccagctca gcggtaaact gaacacgatc cgcgaacttg
     1081 tccatgaagc tcagggtctg accggtgacg ctttcctgaa tcgtgccgtc ctctatcgcc
     1141 agcgtgaaga cctgaccagt gaagttgttc agatagacat taagtctatc atggacggca
     1201 cttccccaaa ccttgcccta atgaagaatg acatcctcta cattccaagt atccatgacc
     1261 tggaagaccg gggtaatgtc acagttcacg gtgaggttgc ccaccctgat tcctatcctt
     1321 atgcggataa catgacactt gaggatctga tcattcaggc cggtggcttg aaagaagccg
     1381 cctctactgt ccgtattgat atatcgagac gaatcaagaa tcctcgtagt actgcggata
     1441 atgatacgat tggtcagatg tataccttct ctttaaagga tggttttgta atagatggtc
     1501 agcccggttt tatccttgag ccttatgatc aggtttatgt ccgtcgcagt ccgggctatc
     1561 aggcacaaca gaatgtagcc attgaaggtg aaatcctttt cggaggaaat tacgccatga
     1621 ccagccgtga ggaacgtctt tccgatttgg tgaataaagc cggtggtccg accaattatg
     1681 cctatctgcg tggtgcaaaa ctgacccgtg tggctaacgc tagtgagaag aaacgtatgg
     1741 gtgatgtaat tcgccttatg agcaggcaat tgggcgaggc catgattgac tctttgggta
     1801 ttcgtgtcga agataccttt acggttggaa ttgatttgga aaaagccttg agcaatccta
     1861 aaagtaatgc cgatcttgtc ttacgtgaag gtgatgtgat ctccatacct aagaatacta
     1921 atactgtaac tatcaatggt gctgtcatgg ttccgaatac ggtttcttat atgaagggaa
     1981 agaatgtgga ttattacctg aatcaggccg gtggctgttc tgataatgca aggaagagta
     2041 agaagttcat tgtttacatg aatggtcagg tgacgaaggt taagggtagt ggtaagaaac
     2101 agattgagcc ggggtgtgag attattgtgc ctggtaaggc taagaagaaa gggaacatag
     2161 ctaatatttt aggttatgct acttccttca gttctttggg aatgatgatt gcttctattg
     2221 ctaatttgat aaagaaataa atgacctatt atgattgaaa agcaatctta tcaagaaccg
     2281 ttttctgaag tggataaaag gaaagatgat gaaatggaaa tagacttgat ggctattttt
     2341 tataagatta ttactgttcg tggagtacta tgcaaagctg ctggagtggg agtaataatt
     2401 gctatagtgg tggcattgag cattcccaag caatatacag taaaggttac cctttctcct
     2461 gaaatgggta atgcgaaggg aagtaatggt ttagccggac ttgctgcctc gtttttggga
     2521 gatggggctc taatagggga aagcacagat gccttgaacg cttctctttc agcagatatt
     2581 gtttcttcaa ctcctttttt attggaactt ttagaaatgg aagtctccgt ttctaaaaag
     2641 gatgataaaa tgactttggg gtcttatctc gatgaagagt catctccttg gtgggattat
     2701 cttataggtt ttccgggcat agtaatagga ggagttaaat cattattcgg agaagatacg
     2761 gttcctgcca gtggagggcg gcaaggaact atcgaattga cgaaagaagt aaatgagaag
     2821 attaattttc ttaaaaagaa gattagtgca tccattgata agaaaaccgc cataacgagc
     2881 attacggtca ccttacaaaa tccgcagatc actgcggtta tagcagattc tgtcgttcat
     2941 aaattacagg aatatattat tgggtatcga acttcaaaag taaaagaaga ctgtgcgtat
     3001 ttggaacggt tgtttaaaga acgtcagcag gaatattatg ctgctcaaag aaaatatgcg
     3061 gattatgtag acgcccatga taatgtggtt cttcaaagtg tacgtgctga gcaggagcgt
     3121 ttacagaacg acatgagttt ggcttatcag atatatagtc aggttgctaa tcagttgcag
     3181 gtatccagag ccaaagtaca ggaggaaaag ccagtctttg cagtagttga gcctgccgtt
     3241 gtacctttga aaccttcagg tatgggactc aaaatttata ttttattatt tgtgttcctg
     3301 tccgtatctg gtactctcgt gtgggtgttt tttggcaaaa gtctgctggc tagcttgaga
     3361 aaagaactga aaaataagga gatagaacag gataaatgat gctaaaacgt cgtttacaac
     3421 attcttacat caattaaatt cacttactat attattaaac gaatgatacg tacagctatg
     3481 ataatggctg cgggcatggg aacccgtttt ggccaatata cagaattgat acctaaaggg
     3541 ttcgtcaaag tgggaggtat tccaatgata gttcgttcta ttgatacttt gttatcatgt
     3601 gacattgagc gaattgtaat cggtacagga tataaacaag aagtttatga agaattgaag
     3661 acagactatc ctatgcttga aacctgtttt agtcctcgtt atgctgaaac aaatagtatg
     3721 tatactttat ataatacgcg ggagattctg ggcaatgatg attttttatt gttagagtca
     3781 gatttgattt ttgagaaaca agcaataatg agcttattgg agtgtcctgc ggcagatgca
     3841 atgctaataa ctccagtgac aaagtttcaa gatcagtatt atgtggaaca tgatgataat
     3901 tttcgccttt cttcatgttc tgtcaataag aataaactaa acgctaaagg cgaattggtc
     3961 ggcatccata aactatccgg ttccttttac aaaataatgt gtgctgatta tgcgagtatt
     4021 gttgatgaac aacccaattt gggatatgag tatgaattac tacgaatatc ttgttctcaa
     4081 tctcctgttt atgtgcataa agtagaaggg ctgaaatggt atgaaatcga tgacatatca
     4141 gatttggaat atgcagagaa atatattgtt ccgtattgtt aattaaaata atatatcaaa
     4201 ttatgagtaa gacagtttat attgggatga ctgcggatat tatgcatcca ggacttatcc
     4261 gcattattaa tgaggctact aaatacggtg atgttataat tggtcttctt acagataaag
     4321 ctattgcgga gcataaacgc cttccttatc tgacctatga acaacgaaaa gaggtagttc
     4381 agaatattaa aggcgtatgt aaagttgttc ctcaagaaga atggagctat gttgagaatc
     4441 tcaaacgcat taaacctgac tatataattc atggtgacga ctggaaaacc gggcctttac
     4501 gtgaagaacg tgtgcgcgta tttgaagtga tgaatgaaca gggaggaaag gttatcgaaa
     4561 ttccatatac tttgggaatt aattcatctt ctttggataa agatattaag gctataggta
     4621 caacccctga tgtacgttta aaatcacttc gtcgtttgat aaatgccaaa cccgtagttc
     4681 gtattttgga agctcatgat ggactatgtg gcttgataat tgaaaatcag gaaatattaa
     4741 aaggggataa gagggaagta tttgacggaa tgtggtctag tagccttacg gattcaacca
     4801 gtaaaggtaa acctgatatt gaggcggttg atttaactac ccgattgcaa gatttgaata
     4861 atattctgga gtgtactact aaacctatta tttttgatgg agatacaggt ggtaaaattg
     4921 aacatttcgt atttacagta cgcactttag aacgtcatgg aatttcagct ataataattg
     4981 aagataaagt tggattaaaa aagaattcat tgtttggtac agatgttatt caaactcaag
     5041 atacaatcga aggtttctgt aataagatca aagcaggaaa ggcatctcag attactgatg
     5101 attttatgat tatcgctcgt attgagagcc ttatagcggg aaagccggta agtgatgctt
     5161 tagagagagc ttttgcatat gtccaagcgg gagcggacgg tattatgata catagcaaaa
     5221 ataagtcggg tgaagatata aaagaatttt gtttggcgtt tcgaaaacag tatgctcatg
     5281 tacctatcgt ggttgtgcct actacatatg atcatattta tgagtctgaa ttgtgtgatt
     5341 ggggtgtgaa tataattatt tatgctaatc atatgcttcg tgccgcttat cctgctatga
     5401 tgaatgtcgc aaagataata ttagagaatg aacgtgcttt agaggtgcgc gaactgtgta
     5461 tgcccataaa agaaatattg gaactgattc caggtactaa ataaaaagag gaatatcatt
     5521 atgttaagcg tagaaaaagt ttatgaaacg tttctgagtc atgacgttga tttttttaca
     5581 ggagttccag actcattact aaaaaatatt tgtgcctata tcacagacca tacttcacgt
     5641 gagaaacata tcatagctgc taatgaaggt gcggctgtag gaattgcttc aggttattat
     5701 atggcatcag gtaaggttcc tgtggtttat atgcaaaatt ccggcttggg taatactgtt
     5761 aatcctctgc tgtctcttgc agatgaacaa gtatacagtt ttccaatgct tttgatgatt
     5821 ggctggcgtg gtgaaccggg aacaaaagat gaacctcagc ataaaaaaca gggtgaggta
     5881 actttagatt tgttgaaagc aatgcggatt ccttatataa ttcttgattc aaatgagaat
     5941 gatgcattta ttcagctcca tgatatcata caatcagcaa aaactaagaa tattcctcat
     6001 gcaataatta ttcggaaaga tgtttttggc aaatataaac ttcaaaaaga gttcggatgt
     6061 aattatcctt tatctcgtga ggatgctttg caaatagttg tggattatct gcctgaaaat
     6121 tcagtggtcg tttctactac tggcaagctt tctcgtgagt tatttgaata tcgagaaatg
     6181 aaagagcaag gtcatgaaca tgattttctc acggtaggct ctatgggaca tagttcatca
     6241 atctctttgg gtattgctat agcaaagcaa gatagacctg tttattgctt ggatggtgat
     6301 ggagcattta ttatgcattt aggggcaatt agtaacattg gcgatttatc tcctaaaaac
     6361 tattatcata ttttgtttaa caatggtgct cacgagtctg taggaggaca gcctacttta
     6421 ggatttagtt tagatattcc ggctattgtc cgggggagcg gatataagca tacttatact
     6481 gtttgtacaa aagttgaaat tgaagaagca atgaagcagc ttccaaagtt atgtggtcct
     6541 gttttgttgg aaataaaggt taaaatagat tctcgggaga atttgggacg tcccacgact
     6601 actcctatag agaataagga gcattttatg gattttttaa aataaatata ttcgatgaaa
     6661 atagaaagaa aaatattatt aaatcctggg cctgccacta ctactgacag tgtaaaaatg
     6721 gcacaagttg ttccggatat ttgtcctcgc gagaaagaat tcgcaggtat gatgaaacaa
     6781 cttcgggacg atttggtcag agttgctcat gggaatttgg aaaaacatac cgctgtatta
     6841 ttttgtggct caggaaccat caatattgat atatgtctaa attctcttct tcctgaagac
     6901 aaaagggtgc ttatagtgaa taatggggca tatagtaccc gtgctgtaga agtgtgtcaa
     6961 tattatggtt tgcctcatat taatttggaa ttttccgttt acgaacgtcc tgatttatcg
     7021 gtggtggaaa atgtgttgca agaaaatcct gatatagcta tggtttatac tactcatcac
     7081 gagacgggta caggaattct gaaccctatt cgcgagatgg gcgctatagc tcataaatat
     7141 caggctaaat ttgtcgtcga tactacttct tctttgggca tgattccttt tgatatagag
     7201 aaagataatg tggatttttg tatggcatct gctcaaaaag gacttcaagc gatgacaggt
     7261 ctttctttta ttataggcaa tgaggaacag attaagtttt caaaaaaata tcccaagcgt
     7321 tcttactatt gtaatcttta tttgcagtat gagaattttg agagaacagg tgaaatgcat
     7381 tttactccac cggtacaaac tatttacgcc actcgtcagg cattaaatga atattttgaa
     7441 gtgggtgaag aagctaagtt tgcccgtcac aaaagagttt ttgaggctat tcattcaggt
     7501 ataaatgaaa ttggtcttaa aagtgtaata aagcgtgaat ggcagtcagg actggttgtc
     7561 tcagttcaat acccagaaga tcccaactgg gattttgaga aaatacatga ttattgttat
     7621 gagcgtggat ttacgattta tccaggtaag atatcaactg aggatacttt tagaatctgt
     7681 gctttaggag agatagaagt agatgatatt gagaacttct ttaaagtact aaaagctgca
     7741 ttaaatcatt ataacgtcac attaccgatg tcatgattgc agaaatatta ttgaagattc
     7801 gtcattttta tttttccctt cgtggtatac acttccatcc ggaaagtgtt atttctggag
     7861 tgcctattcg tagctttcgc ttagtaggca aatatggcaa tattaatttg aggtgatgca
     7921 ttaggagttc tttattctta taaaaaggca tcggtagtta taggagataa tgtttgtgta
     7981 gggtaatttg cttttagtgg gagagaccat attagaattg cggtaagggg cgaagaagat
     8041 aataaccaat tagtgagaat attggaaaaa tataattgat atcggtaaat gtagttgttt
     8101 ttatactgta tttaagtaat ggaaaatcta aagcagaaaa ctgtatcagg aataatgtgg
     8161 agcgctatag aacgtttctc tttacaagga gtacagttta taattcaaat aatattagct
     8221 cgtttgttac taccatcgga ttatggtatg atcgggatgt tagctatttt tcttcaagtc
     8281 gctcaagtat ttatagatag cggttttaca aatgctttaa tccagaaaaa agatagaact
     8341 gaagaggatt ttgccactgt cttttatttt aatattcttg tcgcagtatt attctatggt
     8401 atattgtttt tttcggcttc tttgattgca gacttttata atatgccgac tttagttctt
     8461 gtaattcgtt ttatagcatt gtcgttgata ataaatgctt tatcggctat tcacagaacg
     8521 aaattaatta tttctgtaaa ctttaaaact caatctaaaa tttcattagg tgcagctttt
     8581 atatcaggcg tgattggaat atggatggct tatgtcggtt gcggggtttg ggctttagtt
     8641 tggcaaactc tcttaaatag tataattttg acaattttgt tttactgttt agttcattgg
     8701 aaacctttac atactttctc caaaagttct tttgaaagat tattcaattt cggatctaaa
     8761 ttattgatct caagtcttat caatacagta tatcgtaatc tgtataccat tgtaatagga
     8821 aaaaagtttt ctgttgtaga gcttggttac tatacaagag cagaacaatt tgctattttt
     8881 ccttccaata atttaaatgc tttagtttct agagtagcgt atcctatttt aagttccatt
     8941 caagatgatg ataaatgttt aacaaacgca tatcgaaatt atatcagatt atcctcatat
     9001 ataatttttc ctttaatggt aggtttactt gttttggcta atcctattat tagtctattg
     9061 ttaacagata aatggtctgg ggttgttatt cttttacaga tattatgttt ggattggatg
     9121 tttgatcatt tgagccaaat taatttgaat ttattatggg ttaaaggaag atctgatctg
     9181 tcgttacgtc ttgaaataat aaaaaagacg attgctatat tcattctttt tgtgtcaatt
     9241 ccatttgggc ttgaggtgat gtgttggggt agagttattt actctctgat agcgacatat
     9301 ttgaatacat attatactaa ttctcttatt gatttgacct taaagttgca agttaaagat
     9361 gtatttccaa gtttaatact ctctttcata atggggggga tcgtttttat atgtatttct
     9421 ttctttgaaa ctgatatagt aaaaattgtg attggatgta ttactgggat gtccttctat
     9481 attttacttt cttttctttt taagctagat tctttttttt gtattttaac attgatcatt
     9541 aaaactaaaa acatagatga aaatattaaa aaagattttt caagtaatag taaagataat
     9601 taaccattgt gtgccagttg atagtagatc attgtatttt attcctcatc ctaattgtag
     9661 aacagataaa tatgatatta taaattattc gtcagataat gttctcgttc tgttaaatta
     9721 tttgctaaaa aaagatagtg ctgaatatta taaaatatat gttgaaattt atgattcttc
     9781 tcgtatttca gaatatcaag aatatattta tggcataaat cctaatatta ggtgtacttt
     9841 tttatgtgca tgtgttggac gttttttctt taataaagta tcttttaagg atatgttgta
     9901 tgcctttttt tgtttttgta gagcaagtaa atgttttaca gctacttttt attatgattt
     9961 ttcatttaaa aaacgctctc aacagattat ttgtttgggg tattatactc cattcaaaga
    10021 tgattatcat atgggagatc attcttatga taaatttcgt aatacaacat gtaactcatt
    10081 tgattactct attgctactt cttgtttaag tgctagaata atttcaatag attgtggaat
    10141 ctcatatgat aaattcaaag tcttaggatt tcccagaaat gatttgttga tatcgaaaaa
    10201 taattgcaat gttattaaaa gagaaatttc gaaatttgcg ggatatgatg taactaaata
    10261 tatagtttat actccaactt ttcgtgatta tgagactgtt actgaaggta atttgcgttc
    10321 aatactcgga tatgttgatt gtgatttgtt gaagttatcg aaaatactat tgaagtttaa
    10381 tgcggcttta attcttaaat tacatccttt gcagaataaa acagtcttaa aaaaagattt
    10441 acccaaaggt atacttgttt ttgaacaaac atataaatat ggattgtatg atcttttgtc
    10501 attttcagat ggaatgatta ctgattatac ttctacctat tttgattttt tattggtaaa
    10561 taagccagtc atatttaatt tctacgatat tgaagaatat cgtagagtaa gaggtttctc
    10621 atttgagcca atagaatttt tttgtgcagg tgatattgtt tacaattata atgaattgat
    10681 agatgctgtg atgggacttc tggctgggaa agatattcat gctgaacatc gacgtcatat
    10741 ttctttattg atgaatcaat ttcaagatga taattcaaca aagagaatat gtgacatatt
    10801 tttaaatgaa atataataaa taaaatgaat tatgcatttg tggtgcaggc acgtttaggt
    10861 tctacacgtt tgcctggaaa aatattgaaa cctttctatg gtaatcaatc gattcttgac
    10921 ttaatggttc ataagctttc tgctatatcg aatattccag taattattgc tacaacaaat
    10981 tctgttatca atgaacctat tgaaaagaag gcacttgcat taggggtaaa gtgcttcaga
    11041 ggtgaggaga atgatgtttt aaaacgattc attgatgttg ctgaatattt tgatatacag
    11101 ggtatattcc gaatatgttc tgataatcca tttttagatg tacatgcggc aaggcaattg
    11161 gtcgaaatag caatgaaatc ttgtaacgat tatataagtt ttgatattga tggtactcca
    11221 tcaattaaaa ctcatttcgg tttttgggga gaatttgtaa cgcttgatgc gctgaagcga
    11281 gttataggat ttactgatga tttattgtat cgtgaacatg ttactaatta tatatatagt
    11341 catcctgaac tttttaatat tcaatggatt tcaggatctc cagtcgtgtc aaaacatcat
    11401 aatattcgac tcacgattga tacgttagaa gatttttctg tagcacagag aatatatagg
    11461 gatttacaag aaaaaagagt ggaaatatcg atagaagtga ttgtagacta tgttcgaaga
    11521 catgcagaat acattcaact gatgaaacaa caaataaaaa aaaattctaa ataatgaaga
    11581 atacttatat tattggtgaa atagggcaga atcataatgg ttctgttgac ttggctaagt
    11641 tgattattga attaatctca cgacctgtac atgaggatgt ttttggtatg gatttcatgc
    11701 caatgaatgc tgttaaaatg actaaaagag atttatcaga agaattggct gtttctcaaa
    11761 tgaatcaaat atatgacaat cctaattctt ttgggcgtac ttatggtgaa catcgtgctt
    11821 ttcttgagct tgatgatcaa gcgcattttg agatttataa atatgctaag tcattaggat
    11881 tagattttat cgagacgtta tgtgccaaag gatgtctgtc tttgcttaaa ctgttcacac
    11941 cggataggct aaaagttgct agtcgtgatt tgactaactt accattgctt gaagcattag
    12001 cagaaactca tattcctatt atattatcga caggaatggc tggtcaaaga gaacttgaca
    12061 atgcattaga tgtgataacg agatatcata gtaatatagc tattctacat tgtgtatctc
    12121 agtatccaac tcatccaaat aatttgaatc tacgtacaat aacatatttg aagaagcatt
    12181 acaataagtt tgagataggt ttttctgatc atacaatagg tatttctgct gctacagctg
    12241 ctgtagcgat gggagcggaa attatagaaa agcatgtaac aattgatcgg catatgaaag
    12301 gaacagacca gcttggctct ttaggtccag atggggttaa tcgtatgatt cgagatattc
    12361 gcatagcaga gtgttggctt ggtactgaag atctttatat agaaaaaggg gtggagaagt
    12421 ctaagataaa acttgaacgt tctattgcca ctcgaaaata tattccagca ggtagtatta
    12481 ttcaagagtc ggacattcat ttactgagtc ctggtgatgg ttataaatgg atagataaaa
    12541 aaaatgtaat tggtcatttt gctaaacaag atatatcagc gaatgaaata atatatcctg
    12601 attttattga atagatatat tcctactgca acttgtatta cggtatagag tactgcctgc
    12661 tataagctaa gtagtgatta ataaataagg gtaaaatact aaaaaaatga aagagataaa
    12721 gcttatactt acagatattg atggcgtttg gactgatggc ggaatgtttt atgatc
//
