LOCUS       c00037_gnlPro..        13599 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKKAMGKE_37.
ACCESSION   c00037_gnlPro..
VERSION     c00037_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 23:55:28
            Original ID  :: gnl|Prokka|FKKAMGKE_37
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13599
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13599
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[640:3599]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      641..3599
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13599
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13599
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(438..551)
                     /locus_tag="ctg37_1"
                     /transl_table=11
                     /translation="MLNSIKIPIYGEKLDSSYYFQIYFSNIFLRNNLQVKK"
     CDS             641..2869
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_2"
                     /sec_met_domain="Gly_radical (E-value: 3.1e-46, bitscore:
                     148.8, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1164.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFKDGLWSKEINVRDFVSNNITPYEGDASFLQGPTERTKA
                     VWNHCLKALEEERNNNGIRALDYTTVSTITSHPAGYIDKENELIVGLQTDQVLKRAIKP
                     FGGINVVMKACRENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGLDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKEIK
                     VLGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSQ
                     GTITETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESIGGRFNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNMTVLWSPELPEGFKAFCAQVSIDTSSVQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKDIPVLTGETL
                     KFEEVMANYKKVLIQIARVYNEAMNIIHYMHDKYYYEKAQMAFVETDPRINLAYGVAGL
                     SIAIDSLSAIKYAHVKARRNDIGLTEGFDIEGAFPCFGNDDDRVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGIAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATQEDRIDNLVTMMDGYFTKGAHHLNVNVLN
                     REMLQDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             2874..3599
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_3"
                     /sec_met_domain="Radical_SAM (E-value: 4.2e-30, bitscore:
                     97.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIEAKGG
                     TATDPEEIVRMAVSQKAFFGKKGGITFSGGEPTFQAKSLIPLFKRLKEAGIHICLDTNG
                     GLWNNDVEELLELTDLVLLDIKEFNPEHHQSLTGRSNEQTLKTAAWLETNHKPFWLRYV
                     LVPGYSDFEDDIRQLGEHLGTYQMIQRVEILPYHTLGVHKYEAMNKEYMLKGVKENTPE
                     QIEKAEKLFRQYFRTVQVN"
     CDS             complement(3832..5091)
                     /locus_tag="ctg37_4"
                     /transl_table=11
                     /translation="MKEDEKWIKAFKDKLEDYSEPMPASGWERLERELMPVTEKRIYPY
                     RRWAVAAAAVVLVVTTAVSLYFLNSPVADEIRYATAPSLAVNPDVLPEPALPDVQVAVS
                     EPVKPVGTTSINPVSGYLAKNTDPVIVPEVSSLAEKQPEAVTEEKRAEPQQEATAAIEK
                     KESVTAQPPKRKEARRPSGKDKYQLPIGDSSAKRGGKWSMGVGIGNGGGLPTNGSENFA
                     PRPMTNRVDLMTIMNGAVSIPADQEVIFEEGVPYLKSNTTAVVDYEHHQPVSFGLSVRK
                     SLPKGFSVETGLTYTLLSSDIKRQGDTKMQSQKLHYIGIPVRGNWNFLEKKYFTLYVSA
                     GGMVEKCVYGKLADDKVNVKPLQFSVAGVVGAQFNATDHVGLYVEPGVSYFFDDGSKVQ
                     TIRKERPCNFNLQAGLRFTY"
     CDS             complement(5146..5694)
                     /locus_tag="ctg37_5"
                     /transl_table=11
                     /translation="MNELELSERCRQGDNRARKELYEQYAGRMLGVCLRYAGDRDMAQD
                     LVHDGFLKIFDSFDKFTWRGEGSLRAWMERVMVNTALQFLRKNDVMNQTTALDEVPETY
                     EEPDASAVEAIPQKVLMQFINELPAGYRTVFNLYTFEDKSHKEIAQMLGINEKSSASQL
                     FRAKSVLAKKVKEWLVTNG"
     CDS             5882..6634
                     /locus_tag="ctg37_6"
                     /transl_table=11
                     /translation="MKKFNLITFAVILMLLPILQSCLDDANNDEWVTCPPGGILAIGTM
                     KIPNADTPRDFFIALDNGDNVLPADTADIRNRKYTVAEGQRVFVGYLQMGEEKPGYENG
                     KIFTIEDILTKEIIPLTEATADSIGDDRINVTAHALTKDYLTIEYQYLGSMNENKKHML
                     NLVQNEITGPIKDDGYIYLEFRHNAFNDSPNQLGSSLVSFKLDSIAEQLATAKGIKLRV
                     NTIYDNIQYVTIDINEDKNLKIKSFHSQ"
     CDS             complement(6739..7737)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     -3.5; E-value: 38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg37_7"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-46,
                     bitscore: 150.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 6.4e-18, bitscore: 57.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVKLKISIFALIDSISLINQRTMTIQQLEYILAVDQFRHFAKA
                     AEYCRVTQPTLSAMIQKLEDELGVKLFDRSMTPVCPTAIGKKVLEQARKILSEVICVKE
                     IISEEQHSLSGTFRLAVLPTIAPYLLPRFFPQLMEKYPDLDIRVMEMKTPDIRKALLTG
                     EADAAIIASMLDDAALTEETLFYEQFLGYVSKKEPLFKHDVIRTSDVTGERLWLLDEGH
                     CFRDQLVRFCQMEAVKISQMAYRLGSMETFMHMVESGKGITFIPELAVMQLSEEQKELV
                     RPFAIPRPTRQIVLVTRKDFIRTSLLQVLKEEIQAAVPKEMLTLQAVQCLV"
     CDS             7807..8280
                     /locus_tag="ctg37_8"
                     /transl_table=11
                     /translation="MKTLNYTHLEEKGANTIVLSLQQLLADFQIHYANLRGFHWNIKGH
                     GFFVLHSKFEDLYNGAAEKVDEIAERILMLGGTPANKYSDYLKMAQIKEVDGVNKADDA
                     LNHILETYGHLIAEERKILSLASSHNDEVTVAMMSDYLKEQEKMVWMLTAYNG"
     CDS             complement(8384..9382)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_130"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_9"
                     /sec_met_domain="Glyco_hydro_130 (E-value: 1.9e-69,
                     bitscore: 226.4, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEIKIAGAALPAMPWEERPAGCKDVVWRCSANPIIPRDLLPTSN
                     SIFNSAVVPFKDGYAGVFRCDDTNRRMRLHVGFSKDAVHWDINEEPLKFQCDDAEVGTW
                     VYGYDPRVCFIEDRYYVTWCNGYHGPTIGVAYTYDFVTFHQLENAFIPFNRNGVLFPRK
                     INGRFAMLSRPSDNGHTPFGDIFYSESPDMEFWGRHRHVMSPAPFEDSAWQCTKIGAGP
                     IPIETSEGWLLIYHGVLASCNGFVYSFGSALLDIDQPWKVKFRSGPYLISPQKDYECMG
                     DVPNVCFPCAALHDSETGRIAIYYGCADTVTGLAFGYIPEIIEFTKRTSII"
     CDS             complement(9437..10705)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_10"
                     /sec_met_domain="MFS_1 (E-value: 5.4e-11, bitscore: 34.4,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKPISPVCWVPTVYFAMGLPFVALSMVSVLMFSDMEVSNAQIA
                     FWTSLIMLPWTLKPLWSPFLEMFKTKKYFVVATEIITGLAFALVALSLPLPDFFRYAIA
                     LMGIIALSGATHDIAGDGVYLTELTATQQAKYIGWQGAFYNLAKILANGGLVWLAGMLK
                     DEFGVVHAWMIVMLMCAGIMILIGLYHIRILPSGGGASGEVNTMSDALNMLWEVIRSFF
                     QKKHIAFYIVFIILYRFAEGYAIKIVPLFLKASVADGGLGLSTQDIGLVYGTFGAGAFI
                     LGSLLAGYYISAFGLRKTLFSLCCAFNIPFLVYFLLALYQPSDLWIIGMAIVSEYLGYG
                     FGFVGLMLFMMQQVAPGKHQMAHYAFATGIMNLGVMLPGMMSGYLSDWLGYRDFFIWVL
                     IATIPAFIVTWLVPFTYPDGKKK"
     CDS             complement(10955..11968)
                     /locus_tag="ctg37_11"
                     /transl_table=11
                     /translation="MNRHLNFVTLICLITGFVSLASCSNDDDEMDKYQKIYIRTGVAPG
                     AEMGAAVVVDCVSNSSTADRSDFEIQLCAVQPVTRDVTAALGVDTLKVDTYNSANKTKC
                     KLLPQDNYTIETSEVVLKTGQTVADSSFQVVLKNIEKLTNPDGYVLPVTLKGVTGMDEQ
                     AVSTSMKTVYIRIYTSVLYTSYTKPGNWSAVDRSAWSVSCSNVYADDDAKYGAHLAIDG
                     EINTTWFTWGVANAGECWWNTVLDRPVTLTGFSVTKQSAYGSGYNLRSAEIKVRKEGET
                     EWVTYPRVLTFRNFKGADPQYAAIEPPIPNVKEFRINCLTPDNYTGFAEINLYVKQ"
     CDS             complement(11991..13100)
                     /locus_tag="ctg37_12"
                     /transl_table=11
                     /translation="LFACFVLPMILAGCNDADYQVIDNAIYLNEASENGSAKVTVDPEN
                     VTTTTLTVRVGQPVTENVTAVLTVDPSILKEYNEANETSYEVLPEQYFTYDKEIKIAAG
                     DVSAIPSEFRVKPYSNENGELYAIPVSLTEIQGPVSTIGLSSKFIILLDKPLIQSVPFM
                     NTTNAVKPAKDELWGVTTNEWSLEAWVQMDGFDINNQAIFNSGSSDHEVYIRFGDAMIP
                     YNSLQVKTLGSQVNTVTLFEKNKWYHLAFVYNSSGLLSIYINGVLDVTLQTKGGPVRFD
                     KMNMVSSGSYFRNNCQMAQVRLWKSAISQTQIQSNMYFAVKPADPNLIGYWKMDEGKGN
                     AFADCTGHGYDLVAGGTLVWKEHVRFDKQ"
ORIGIN
        1 aaaaaagaac cttgaatgtc gatttcataa ctcacttttt ttagttgcaa aattaatttt
       61 tacctctcgt tttcgagtta tgcagactat ggactaatca agtcattatc aggtcattta
      121 tggacaaatc gttaccgttt ttgtccggcg gggaataggt aacgatttag taacgaaact
      181 ttgtctttta ccgtactttt gaagtcttgg aagcaggact ttcgggcaat aaaaaaagcc
      241 acaaatcatt gatttgtagc tttttgtccg tttgctgacc atttctgtcc agcacgttca
      301 gcggagagac agggattcga accccgggta cctcgcagta caacggtttt caagaccgcc
      361 gcaatcgacc actctgccac ctctccagaa ctacggttaa gtagtgcttt tctcttaaag
      421 cgctgcaaag gtacgaatca ttttttaact tgcaaattat tccgcaaaaa aatattagaa
      481 aagtatattt ggaagtaata actgctatct agcttctccc cataaatagg tatttttatg
      541 ctattcaaca taaaatagga cccttttata tacctaaacc gaaaaaaggt tgtaaatttg
      601 cgcgctctaa aggataacta accactaact gattaatttt atggaactga ataagacctt
      661 taaagatgga ctttggagta aagaaatcaa tgtaagggat ttcgttagta acaacatcac
      721 tccttatgaa ggggatgctt ctttcctgca aggacctacc gaacgcacca aagctgtctg
      781 gaatcactgt ctcaaagctc tcgaagaaga gagaaacaat aatggtattc gtgcactcga
      841 ctacacaact gtatctacta taacctctca ccctgccggc tacatcgata aagagaacga
      901 actgatcgtc ggactacaga ccgatcaggt gttaaaacgt gccatcaaac cgtttggcgg
      961 aatcaatgtg gttatgaaag cttgccgtga aaacggagtg gaagtagatg acagagttaa
     1021 ggatatcttc actcactatc gcaagactca caatgatggg gtattcgatg tgtataccga
     1081 agaaattcgt tcgttccgtt cattgggatt ccttaccgga cttcccgaca actatgcacg
     1141 cggacgtatc atcggtgatt atcgccgcct ggctctctat ggtcttgacc gtctgataga
     1201 agctaaaaaa gaagatctgc ataatctgac aggtcctatg actgaagccc gcattcgtct
     1261 tcgcgaagaa gtagccgagc aaatcaaggc cctgaaagag attaaagtat tgggcgaata
     1321 ttatggtttg gatctgagcc gaccggcata taccgcacag gaagctgtac aatgggtgta
     1381 tatggcttat ctggctgccg taaaagagca ggatggtgct gccatgtcac tgggtaatgt
     1441 atcttcattc ctcgacatct atcttgaata tgaattaagc cagggtacga taaccgaaac
     1501 attcgctcag gaactgatcg accaattcgt tatcaaactc cgtatggtac gccacttgcg
     1561 tatgcagtcg tacaacgata tttttgcggg tgatcccaca tgggtgaccg aatctatcgg
     1621 tggacgtttc aatgatggac gtaccaaagt tactaaaact tctttccgct tcttgcagac
     1681 actttataac ttaggcccgt caccggaacc taacatgact gtactatgga gccctgagtt
     1741 gcccgaaggt ttcaaagcat tctgtgcaca agtatctatc gacacttctt ccgtacaata
     1801 cgaaaacgac gacctgatgc gtgaagtccg tcaatcggat gactacggaa tcgcttgttg
     1861 tgtttcatat caggaaatcg gaaagcagat tcagttcttc ggcgcacgtg ccaaccttgc
     1921 caaagccctg ctactggcta tcaacggagg acgttgcgaa aatacaggta cagttatggt
     1981 aaaagacatc cctgtattga ccggtgaaac actgaagttc gaagaagtaa tggccaacta
     2041 taagaaagta ttgatacaaa ttgcacgtgt atacaacgaa gcaatgaata tcatacatta
     2101 catgcacgat aagtattact acgaaaaggc acagatggct ttcgtggaaa ctgatccccg
     2161 cattaacctc gcttatggtg tagccggact ttcaatcgcc atcgattcac tgtccgccat
     2221 caaatatgca catgtgaaag cccgtcgcaa cgacatcgga ctgacggagg gattcgatat
     2281 cgaaggtgct ttcccttgtt tcggtaatga cgatgaccgt gtagaccacc tgggtgtaga
     2341 cctggtatat ttctttagcg aagaattaaa gaaactcccc gtatataaga atgcccgtcc
     2401 taccctctcg ctgctgacta tcacttcgaa cgtaatgtat ggcaagaaga ccggtgccac
     2461 tcctgacgga cgcgccaaag gcattgcctt tgctcccggt gccaacccca tgcacggacg
     2521 tgataaaaat ggtgcaatcg cctcactgag ttctgtagcc aagttgcgtt atcgcgactc
     2581 acaggatggt atcagcaata cattctcgat cgttcccaaa tcattgggag caacacaaga
     2641 ggaccgtatc gacaatctgg tgaccatgat ggacggatat tttacaaaag gcgcacacca
     2701 cctgaacgta aacgtgctga accgggaaat gttgcaggat gcgatggaac atcccgaaaa
     2761 gtatccgcaa ctgactatcc gtgtctcagg atatgccgtt aatttcgtga aattgagccg
     2821 cgaacatcag ttggaagtaa tcagccgcag tttccacgaa agaatgtaat tgaatgataa
     2881 acgtacactc atacgagtca atgggaacat tcgacgggcc gggtctccgg ctcgtcgttt
     2941 tccttcaagg gtgtaacttc cgttgcctct attgtgccaa tccggacaca attgaagcca
     3001 aaggagggac agcaaccgat cctgaggaaa tagttcgcat ggccgtcagt cagaaagctt
     3061 tcttcggtaa aaagggaggt atcacctttt ccggcggaga gcctactttt caagcaaaat
     3121 cgcttatccc actttttaaa agactaaagg aagcaggaat ccatatttgc cttgatacca
     3181 atggcgggct atggaacaat gatgtagagg aactattgga attgactgat ctggttttat
     3241 tagatatcaa agaatttaat ccggaacatc atcagtcttt aaccggaaga agcaacgagc
     3301 agaccctgaa aaccgcagcc tggcttgaaa ccaatcataa accattctgg ttgcgatacg
     3361 tattagtgcc cggctacagt gacttcgaag acgatatccg gcagctggga gagcatcttg
     3421 gaacgtacca gatgattcag cgtgtagaaa tattgcctta ccacaccttg ggcgttcaca
     3481 aatatgaagc aatgaacaaa gaatatatgc tgaaaggagt gaaagagaat actccggagc
     3541 agatagaaaa ggctgagaaa ctattcaggc aatacttccg gaccgtacaa gtgaattgac
     3601 ttatataagt gtcgaaattc gtattcgcca cagattacac gaatttacac agataaagat
     3661 tcattggcaa tcaacagatt aagttcattc tgcggtgaat tatgacgact gcacttattt
     3721 ataattttgt aagtcacgat ataaaagtct ccctgttctt gccttaattc attacaatac
     3781 aaggcaagaa cagggagata atgtaaccgg catatttttt gccaccctac tttaataagt
     3841 gaatcgcaat cctgcctgca agttaaagtt acaaggcctt tcttttcgga tggtttgtac
     3901 tttggagcca tcatcaaaga aatacgaaac tcccggttcc acatataggc cgacatgatc
     3961 tgtcgcattg aattgcgctc ccacgacacc ggctacagaa aattgcaaag gcttcacatt
     4021 caccttatca tccgccaact ttccataaac acacttttca accattcctc cggcagatac
     4081 atagagtgta aaatatttct tttccagaaa attccagttt ccacgtacag gaatacctat
     4141 ataatgcaat ttctgactct gcatcttggt atccccctgc cgtttgatgt cagaagacaa
     4201 caacgtataa gtcaatcccg tctctacaga gaaacctttg ggaagagact tacgtacaga
     4261 cagtccgaag ctaaccggct gatgatgttc ataatccacc acggcagttg tattggactt
     4321 caggtaaggg actccttctt caaatataac ttcctgatcg gcaggaatac tcacagctcc
     4381 attcatgatc gtcatcaagt cgaccctgtt agtcatcgga cggggcgcaa aattttcgga
     4441 accatttgtc ggaagtccac ctccattacc gatacccact cccatcgacc atttaccacc
     4501 acgtttagca gaagagtctc cgataggcaa ctgatacttg tctttaccgg acggtcgccg
     4561 cgcttctttc ctctttggag gctgcgctgt cacactttct tttttctcga ttgccgcagt
     4621 tgcttcctgt tgcggctcag ctctcttttc ctccgtcact gcctccggtt gcttctctgc
     4681 cagggaggat acctccggaa caatcaccgg atcagtattc tttgccaaat agcccgaaac
     4741 agggttaata ctcgtcgttc ctaccggctt aacgggttcg gatacagcta cctgtacatc
     4801 cggcaaggca ggttccggca atacatccgg gttgacagcc agtgaaggag ccgttgcata
     4861 acggatttca tcagctaccg gactattcag aaaatacaaa ctgacagcag tcgttaccac
     4921 caataccaca gctgccgcag caaccgccca ccggcgatac ggatatattc gtttttcggt
     4981 tacaggcatc agttcccttt ccagtcgttc ccaaccggaa gcaggcatcg gctccgaata
     5041 atcttcgagc ttatccttga atgctttaat ccatttttcg tcttctttca tcattctatt
     5101 tcatttttga aatccaaggt tcacctcagt atctgtaaat acatgtcaac cattggtcac
     5161 caaccattct ttcactttct ttgccaatac actttttgcg cgaaaaagct gtgaggcaga
     5221 agatttttca ttaatcccca acatctgtgc gatttccttg tgcgacttat cttcaaaggt
     5281 gtataaattg aatacggtac gatatccggc ggggagttca ttaataaatt gcatcagcac
     5341 tttctgtggt attgcttcaa cagccgaagc atccggttct tcatacgttt cgggaacttc
     5401 atccagtgcc gtggtctggt tcatcacgtc gttctttctt aagaactgta aagccgtatt
     5461 caccattaca cgctccatcc atgctctcag agagccttca ccccgccagg taaacttgtc
     5521 gaaggagtcg aaaatcttca ggaaaccgtc gtgtaccaag tcttgtgcca tgtccctgtc
     5581 tccggcataa cgaagacaga caccaagcat gcgccctgcg tactgctcat aaagttcttt
     5641 gcgggcacga ttatctccct gcctgcaacg ttccgacagc tctaattcat tcattctcct
     5701 aaacacgtgt ttaccttata aatgcagcaa agatagaaat actgcacaga gagaacaact
     5761 cttttatcac ttttgtttct ttaacatttt aggatgcaat atttcatcac ttcctgcatt
     5821 ttctcaatac aataaagaat aaatctcaat ggataaatag gataaaacca acaagaaact
     5881 tatgaagaaa tttaatttaa taacttttgc cgtcatcctg atgttattgc ccattttaca
     5941 gtcatgtctg gacgatgcca acaacgacga gtgggtcact tgtcctccgg gtggaatatt
     6001 ggccatcggc acaatgaaga ttcccaatgc ggacactcca agggactttt tcattgcgtt
     6061 ggacaatgga gacaatgtac ttccggcaga tacggccgat atacgcaaca ggaaatacac
     6121 tgttgcagaa ggtcaaagag tcttcgttgg ctatctgcag atgggagaag agaaacccgg
     6181 atatgagaac ggtaaaatat tcacgataga agatatattg acgaaagaga tcatcccact
     6241 gacggaagct acagcagaca gcattggaga cgaccgtatc aacgtcacag cgcatgcact
     6301 tacgaaagat tatctgacca tcgaatatca atatctgggc agcatgaatg aaaataaaaa
     6361 acacatgctg aacttggtac aaaacgaaat aacaggtccc ataaaagatg acggatatat
     6421 ctatctggag ttccggcata atgcctttaa tgactccccc aatcaattgg gttcgagcct
     6481 tgtttctttc aagctggata gtatagccga gcaattggcg acagccaaag gaataaaact
     6541 ccgtgtgaac accatttatg acaatataca gtatgtcaca atagatatca acgaagacaa
     6601 aaacttaaaa ataaaatcat ttcattctca ataaaacaac aagaaacacc tacacaatca
     6661 ggcaaaacga gtaataattc tgatacataa aagaaataag gcggcgatgt ttgtgaaaat
     6721 atcgccgtcg tttttatatt ataccagaca ctgaacggcc tgcagggtaa gcatctcctt
     6781 gggaaccgcc gcctgaatct cctctttcaa aacctgcagc agactggtgc ggatgaagtc
     6841 tttccgggtc accaggacaa tctgacgggt aggccgcggg atagcaaacg gacggaccag
     6901 ttctttctgc tcttcgctca attgcatcac tgccagttcg ggaataaacg taatcccctt
     6961 accactctcc accatatgca taaaggtttc catactaccc agccgatacg ccatttggct
     7021 gatcttaacc gcttccatct gacaaaaacg aaccaactga tcgcggaagc aatgcccttc
     7081 gtcaagaagc caaagccgtt cccctgtcac atcggacgta cgaatcacat cgtgcttgaa
     7141 caacggttcc ttctttgaga catagcccag gaattgctcg tagaataagg tctcttccgt
     7201 taatgcggca tcatccagca tgctggcaat gatagcagca tccgcttcac cggtcagcag
     7261 agccttgcga atgtcgggcg tcttcatctc catcacccgt atatcaagat ccgggtattt
     7321 ctccatcagt tgcggaaaga aacggggcag aagataaggt gcaatcgtcg gtaacactgc
     7381 caatcggaat gtacccgaca gggagtgctg ttcttcgctg atgatctcct tgacacagat
     7441 aacttccgaa agaatcttac gggcctgttc cagcactttc ttaccaatgg cagtagggca
     7501 aaccggtgtc atgctacggt cgaacagttt cacccccaat tcgtcttcca gcttctggat
     7561 cattgcactc aaagtaggtt gcgtcacccg gcaatactcg gcagctttag caaaatgccg
     7621 gaactggtcg acagccagaa tatattccaa ttgttgtata gtcatcgttc tctgatttat
     7681 taaagatata gaatctatca atgcaaagat agaaattttc agtttgacac gaatcatttt
     7741 gtgccgtatc tttgttccag ataaaaagaa gaaatatagt attaactcaa aaaaaacaat
     7801 atcattatga agactttaaa ttatacacat ttggaagaaa aaggagctaa caccatcgta
     7861 ctgtcattac agcaactgct tgccgatttt cagattcatt atgcaaacct gagaggattt
     7921 cactggaaca tcaaaggaca cggtttcttc gtactgcaca gcaagtttga agatttatat
     7981 aacggagccg ccgaaaaggt ggacgaaata gccgaacgta tactgatgct gggaggaact
     8041 cccgccaata aatacagtga ctatctgaag atggcgcaga tcaaggaagt ggacggagtg
     8101 aataaggccg acgacgctct gaatcatatt ctcgaaactt acgggcatct gattgcggaa
     8161 gaacgtaaaa tcctgtctct cgcctcttca cacaacgacg aagtaacagt ggccatgatg
     8221 agcgactacc tgaaagaaca ggaaaagatg gtttggatgc tgactgcata caacggataa
     8281 cagccgaaag ggtgtagcca tctgaccgaa aaggtgtagc catacaagca aaagggtgta
     8341 gccatcccgg cgggatagct acaccctttc tgttttattc gattcagatg atacttgtac
     8401 gtttggtaaa ttcaataatt tccggaatgt atccgaatgc gagcccggtc actgtatccg
     8461 cacacccata atagatggca atccgtccgg tctccgaatc atgaagcgct gcgcatggga
     8521 aacagacatt aggcacatca cccatacatt cgtaatcctt ctgaggtgaa atcagataag
     8581 gccccgaacg gaattttact ttccagggct gatcgatgtc aagcagtgcc gaaccaaaac
     8641 tatacacaaa accgttgcag gaagccaata caccatgata gatcagtaac cagccttccg
     8701 aggtttcaat cgggataggc cctgcaccga tcttggtaca ctgccaggca ctgtcttcga
     8761 acggagccgg cgacataaca tgacgatgac gtccccagaa ctccatatcg ggagactcgc
     8821 tatagaaaat atctccaaaa ggagtatgcc cattatcact cgggcggctc aacatcgcaa
     8881 aacgaccgtt tatcttacga gggaacaaga ctccattccg attgaaggga ataaaggcat
     8941 tctccaactg gtgaaaagta acaaaatcat aggtgtaggc cacaccgata gtaggaccat
     9001 gatagccatt acaccaggtc acatagtagc ggtcttcgat aaagcaaacc cgtggatcat
     9061 atccatagac ccaggttcca acctcagcgt catcacattg aaactttaac ggttcttcgt
     9121 tgatatccca atgaacagca tccttgctga atcccacatg caaacgcatg cgacgattag
     9181 tatcatcaca acggaacacc cctgcatagc catccttaaa cggaactacg gcactgttga
     9241 atatactgtt tgaagtaggg agcaagtcgc gcggaataat cggattggcc gaacaacgcc
     9301 acactacatc tttacatcct gccggacgtt cttcccaagg catagccggc aaagcagcac
     9361 ctgcaatttt aatttcttcc atgattcgat taaattaata ttatgtatat atcttgttta
     9421 tattgaaaat ctctttttat ttcttctttc cgtccggata tgtgaaaggt accagccaag
     9481 tcacgataaa agccggtatg gtagcgataa gtacccagat aaagaaatcg cgataaccca
     9541 gccaatcgct caggtatccg ctcatcattc cgggaagcat cacccccaga ttcataatac
     9601 cggtagcaaa agcataatgt gccatctgat gtttgccggg agccacttgc tgcatcataa
     9661 agagcatcaa tccgacaaaa ccaaacccgt aacccaagta ttcagacaca atggccatac
     9721 caataatcca tagatcggaa ggctggtaaa gggctaacag gaaatatacc aagaacggaa
     9781 tattaaaagc gcaacataaa gaaaacaaag tcttccgaag tccgaaagcc gaaatgtaat
     9841 aaccggccaa aagcgaaccg agaataaaag ctcccgctcc gaacgtacca tataccaagc
     9901 cgatatcctg agtgctgagt cccaatccac catccgcaac cgacgctttc aggaacaacg
     9961 gtacaatctt gatggcatat ccttcggcaa accggtacaa aatgataaag acaatgtaga
    10021 aagcaatatg ttttttttgg aaaaaagagc ggatgacttc ccaaagcata ttcaatgcgt
    10081 cactcatcgt attcacttca ccggaagcgc ctcctcccga aggcaaaatc cggatgtggt
    10141 aaagaccgat cagaatcata atacccgcac acatcaacat gacaatcatc caggcatgta
    10201 ccactccaaa ttcatccttc agcatacctg ccagccaaac caagcctccg ttggcaagta
    10261 tcttggccag attataaaaa gctccctgcc aaccgatata cttggcttgc tgggtagcag
    10321 tcagttcagt caggtatact ccgtcacccg caatgtcatg agtcgcacca ctgagagcaa
    10381 tgatccccat cagagcgatg gcataacgaa aaaagtcggg cagcggcagc gaaagtgcta
    10441 ccaatgcaaa tgccagtccg gtaatgattt ccgtagcgac aacaaagtat tttttcgttt
    10501 taaacatttc cagaaacgga ctccataaag gcttcaatgt ccagggaagc ataataagag
    10561 aagtccagaa agcaatctgt gcattcgaca cttccatatc ggaaaacata aggacagaaa
    10621 ccatcgaaag ggccacaaac ggcaatccca tagcaaagta aacagtaggc acccaacata
    10681 cagggcttat cggcttttta ttcatcagtt agttttttat aataattcca tcggttaaca
    10741 attccagtaa gcaaagatag gggatattaa aaacataacc caagattacg acaagaagtt
    10801 gctttcatta tttaataata caactcaccc gggaaaacta ctaacctcta tcaccctttt
    10861 tttattaaac tttatcaata caatacacgc aaagaagcac cgaagacttt catccccgat
    10921 gcctctcgcc cccttatcta caatctaaac acctctattg cttcacatat aaatttatct
    10981 cagcaaaccc ggtataatta tccggagtca gacagtttat tctgaattcc tttacattcg
    11041 ggataggtgg ttcgatggcc gcatattgcg gatcagcccc tttaaaattt ctgaaagtca
    11101 agactctcgg gtaagtaacc cactcggttt caccctcttt ccgaacctta atctcagcac
    11161 ttctcaggtt ataacccgat ccgtaggcac tctgtttagt gaccgaaaat ccggttaagg
    11221 taacaggccg gtccagtacc gtattccacc aacactctcc ggcattagcc actccccatg
    11281 taaaccaagt agtatttatc tcaccgtcaa tagccagatg tgcaccatat ttggcatcat
    11341 catcggcata aacattactg caacttacac tccacgcact tcgatctaca gcggaccaat
    11401 tcccgggttt cgtataactg gtataaagca cgctggtata aatccggata taaaccgtct
    11461 tcatagatgt actgacagcc tgttcgtcca tgcccgtaac tcctttaagc gtcacgggaa
    11521 gcacatatcc gtcaggatta gtcaactttt ctatattctt caaaacgacc tgaaaagatg
    11581 aatcggccac tgtctgtccc gtttttaaga caacttcact tgtttcaatg gtataattat
    11641 cttggggcaa caacttacat ttcgtcttat tggcagaatt gtaagtatcc actttcagcg
    11701 tatctactcc caaagcggca gtgacatccc gcgtaaccgg ctgtacggca cacaattgta
    11761 tttcaaaatc agaacggtca gcagtagagg aattgctcac acaatccacc actaccgcag
    11821 cacccatttc ggcccccggt gcaactcccg ttctgatata tatcttttga tatttgtcca
    11881 tttcatcatc atcgttgctg cacgaagcca acgatacaaa gcctgttatc aggcagatta
    11941 aggtcacaaa attcaaatgt ctattcatat cttatcttct ttttacatag ttattgctta
    12001 tcaaaacgaa catgctcttt ccagacaaga gttcctcctg ccaccaaatc gtatccgtgt
    12061 ccggtacagt cggcaaaggc atttccctta ccttcatcca ttttccaata gcctatcagg
    12121 ttcggatcgg cgggtttcac ggcaaaatac atgttggact gaatttgcgt ctggctgatt
    12181 gcgctcttcc aaagacgcac ctgggccatc tgacaattgt tgcggaagta actaccgctc
    12241 gaaaccatgt tcatcttgtc gaatcttacc gggccaccct ttgtctgcag agtcacgtcg
    12301 agcactccgt tgatataaat cgacaataac ccggaagaat tataaacgaa ggccagatga
    12361 taccacttat tcttctcaaa caaagtcacc gtattgacct gacttccaag tgtcttcacc
    12421 tgtaatgaat tataagggat catagcgtca ccgaaacgga tataaacctc gtggtcgctg
    12481 ctgcccgaat taaatatagc ctgattatta atatcgaatc cgtccatctg tacccaagcc
    12541 tcgagtgacc attcattggt tgtcactccc cacaattcgt ccttggcggg cttcacggca
    12601 ttggtcgtat tcataaacgg tacagactgt atcagcggct tatccagcaa aatgataaac
    12661 ttcgacgaaa gcccgattgt agacaccggt ccctgaattt ctgtgagaga taccggaata
    12721 gcatacaatt ctccgttctc gtttgaataa ggtttcactc taaactcact ggggattgcg
    12781 ctaacatcgc ctgccgctat ctttatctct ttgtcataag taaaatactg ctcgggaagg
    12841 acttcgtacg aagtttcatt agcttcattg tactctttaa gaatagaagg atctaccgtc
    12901 aggacagcag tcacattttc ggttacaggc tgtcccacac gtacggtcag agtagttgtt
    12961 gttacatttt caggatcaac ggtaaccttt gccgaaccat tctcggatgc ttcattcaaa
    13021 taaatcgcat tgtcgataac ctggtaatcg gcatcgttgc atcctgccag gatcatcggc
    13081 agaacgaaac aggcaaacaa acattgtttt attgttattc ttttcataat caaattcttt
    13141 aaagtcattt tacagcagga ttcattattc tgattgcttc acgcaggtac ttatattcga
    13201 tgtcgcccgg atagtcatat tccatgtgat aggtgcctac tccacccttc cgtacctgtt
    13261 ttccgtcaat agtcggagtc cagcgtgcca tgccggcaag tgctctcatt ttgtttccgt
    13321 aacgatctac ataatcacct cctcctgtcg gagcataaga ttcgaaattc tccgtaacga
    13381 tgtacatatt agccactttc tccggaggaa gtattccttt aaagttggca atcgtaccag
    13441 ccagacgtct gtcaagatta gcgtcggaat tacccgcaag gttagagtat gcctgcacaa
    13501 tgaaatagtc aaagtaaggc ccggtttccg gatgaatact ttgaggctcg ccatcaatca
    13561 caagtaaccg tcccgtaccc gatttaggtc cgattcttt
//
