LOCUS       c00027_gnlPro..        14637 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIHFBEEF_27.
ACCESSION   c00027_gnlPro..
VERSION     c00027_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:44:23
            Original ID  :: gnl|Prokka|HIHFBEEF_27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14637
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..144
                     /locus_tag="ctg27_1"
                     /transl_table=11
                     /translation="STYFIDKTFSSQLKTLTYSSFKINNRSTIILYAFNSYRIIIRQLS
                     NE"
     protocluster    1..14637
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1996:4637]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1997..4637
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..14637
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14637
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             256..885
                     /locus_tag="ctg27_2"
                     /transl_table=11
                     /translation="MITQYDLYETPSPKGEDGKKSLHARVCPKKTYTSQEFVEHVAAFE
                     HLPKNQIGGALAAIVDDLCYLLADGNIVELGDLGFFSTSLKCLKDTDDDEDEIKPKSIA
                     FQNVHLRISSEFRKRIKHEMKFQRVHSLTRRQKIVNSTVKERMKKMVSFLKINICITRK
                     EYIGLVGLTPYEAMNELNDFISQGLLRRRGAGRSVVYVAGENLKVE"
     CDS             922..1050
                     /locus_tag="ctg27_3"
                     /transl_table=11
                     /translation="MVRNELVLHINRYCLCLSVVLPLPYQLSFTISINRPDQNPIC"
     CDS             1997..3901
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_4"
                     /sec_met_domain="Gly_radical (E-value: 3.8e-45, bitscore:
                     143.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.5e-244, bitscore:
                     801.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVENSLEAYGYKLDPMTKEIFTKYRKTHNEGVFSAYTDEMLAARR
                     SAIITGLPDAYGRGRIIGDYRRVALYGTEILIAEKKHYLKRLDIQELTEEIIQSREEIS
                     EQIKALKAFEKMCAGYGFDVTKPAKDAREAVQFVYLGYLAAVKDQDGAAMSLGRTSTFL
                     DIYIEKDIREGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQG
                     VDGRSLVTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPENWKRFCAKVSIDTSAIQYEN
                     DDLMRPDYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDERSGVQVAPR
                     FEPITSEYLDYNEVMEKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMALHDGSVER
                     IRATGIAGLSIVADSLAAIRDTKVKVIRDERGLAVGFEREGDYVPFGNNDDRTDSIAVD
                     ITEKFMEYLRQHQTYRNATPTQSILTITSNVVYGKKTGATPDGREGGTPFAPGANPMNG
                     RDTKGAVAALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQIANMVGLLDGYFTPDG
                     GQHLNVNVFDKELLLDAMEHPENYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             3909..4637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.5e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_5"
                     /sec_met_domain="Radical_SAM (E-value: 1.6e-36, bitscore:
                     116.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEIKGNIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWDS
                     KGLAKYQMTPEELLAEVLRYKNFIAKGGVTVTGGEPLLQAEFLREFFRLCREAGIHTAL
                     DTSGYICTPKALAVLEYADLVLLDIKTIDPDLHPRLTAVKLDNTLRFLDELEKRGVPVW
                     IRHVIVPGLTDNDEALDKLAEYISHYTVVQKAELLPYHTMGTYKYEAQGLDYKLKEVEP
                     LSAERLANAKEIFKKHGITI"
     CDS             4687..5628
                     /locus_tag="ctg27_6"
                     /transl_table=11
                     /translation="LSHIVTQIKVGMNMEQHHHDHHHHEITSLNKAFIIGISLNLAFVV
                     AEFTAGFWYNSLGLLSDAGHNLGDVASLVLAMLAFRLAKVHPTCSYTYGYKKSTVLVSL
                     LNAVILLVAVGIIIAESIGKLLHPRPVEGDAIAWVAGIGVVINALTAWLFMKDKDKDLN
                     VKGAYLHMAADALVSVGVVVSGIVIAHTGWYIIDPIIGLLIAFVIIVSTWGLLRDSIRL
                     SLDGVPAGTDIDKVEKTIHSVEGVEGVHHLHIWAISTTETALTAHVSVADISEMERIKQ
                     EIKHDLQHVGIQHATLEFETSGFKCDGHCCSD"
     CDS             5616..5864
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="LLRLKHVYYKPDLLILKDFVYDCIKPFDWIFCSYLESATYLCISN
                     KNKIVITIKIKILWNLLSIHKHPSLKFRHTTTVVSKL"
     CDS             complement(6014..6382)
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MCCRPPVLLLDLTDQIDARFQCFATFFPFGGANFARMFGDELGSF
                     YFTKQFVGVTADTVIVDFCQLNLSFRIYQECTAVSHTVFFDHYTECTAQYACRVCQHRV
                     FDLTNRFRSIVPCFVYEV"
     CDS             6449..7999
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_9"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-46, bitscore:
                     149.3, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSSMRNQLSGIFSGLTNEYIFDIQVSPEHESRKELLELLNDVA
                     SCSDKITVQVADGEGLEFSLLKNGEKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNIPD
                     ESICNRVKALNGPVKLTTYVSLTCTNCPDVVQALNAMATLNPEISHEMVDGAINQEEVA
                     AMKVQGVPSVFADGKLIHVGRGDFGELLGKLEAQYGVKEENLPVVEKNYDVIIVGGGPA
                     GSASAIYTARKGLAVAVVADRIGGQVKETVGIENMISVSQTTGQQLALDLMSHMKDYPI
                     DILEHRRIEKVEVEGREKLLTTSTGEKLIAPAVIVATGASWRRLNVPGESEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGVEAAIDLAGICSKVTLLEFADELKADQVLQDKARSL
                     PNVEIFMHSQTMEVLGNGEKVTGIRIKDRKTEEVRNIELDGIFVQIGLAANSGPFREVV
                     DTNRQGEIVIDSHCRTSVPGIYAAGDVSTVPYKQIIISMGEGAKAALTAFEDRMRGML"
     CDS             8125..9483
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="MSMHEIESLVESSVITVATASPIPPLARNICFNLYQLQNQLDCGY
                     TVLRVREELEKLGYLFLLPPEQLPEPERSAALKLNEEGGFLSDGTYFDHRSDRCCVTAG
                     SLLWTKLIDLGILPESAKTELRELDPLELAELIIPLASKVLAGGDKEDDNYANAADTLG
                     FWYAFFPLFCQMAGMDEEDAPEPERIRALLEMLAVPESFEVLATDEIGKELDDFEEEEM
                     PFLSGWSAPYNEWKNKNNTGDLSLEFCKSMVHDSILKRKFVEADRYASAMEEGPELNRL
                     FHRCLVGMSYYEWVKIQGIKIPIIESVLSQEEAKEGFERVADLSVSSDNVQCARLGIFR
                     ILALQGEYAESVEYLNAVYFKALDECGQKSKELLGQSQRAVLVVVYYRMLEMSIPDSFP
                     GKKELMAHKALNGSDLRKSREILSLLLIEKSEHAYAWQQAFSFCDELIKKYGF"
     CDS             complement(9655..12141)
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="MKRNLLLLAAICSCYNLFAEEVIVKQFRYAGPYEVKKPFLKDSLD
                     VNSKKFTEKELLKTAVPFSNVRQSTQLLEANADGESTLPAGNQSSYIGLASFYLNSDRY
                     VKGTLQVKGPETYEVYVNNEKQTAPDGKVSLSLEPHRYEIVIKYLAESDKAGTLKVSFD
                     TEKEAVITATTDPEKRYTISDVFDGTRFRSVSLSPNGKYLLTSYQTTYPGGQTAYFQQI
                     THKTNGQVLMESSTNNFSWMPQSNRLYYTRKGLQGKELVTVDPVTKAETILSQNLPDGW
                     FSIAPTEDFLIFTISEKGPEKDKDMEEILVPDDRQPGWRNRSFLHKYDLATGVLERLTY
                     GHNSTSLNDISKDGRYLLFTSSRRELTKRPFSTKILYRMDLQNRQVDTLLEDPFINYAS
                     FSPDGKQLAVSGSGEAFNKIGLNIAPEQTSNLADGQLFIYDLSNKQATAVSKDFNPSIQ
                     SFTWNTGDKQIYLQGEDKDCVRLYTLNPANGKISPVPLKEDILSDFTIAENTPELVYFG
                     ESASNSQRLYSMNLKKKEKESVCLKDLSKDILKDITLGEVHDWNFQAAAGDTIYGRYYL
                     PPHFDPSKKYPLIVNYYGGTSPTERSLENRYPSHTYAALGYVVYIIQPSGATGFGQEFS
                     ARHVNAWGKRTGDEIIEGTKKFCEEHSFVDAKKIGCIGASYGGFMTQYLQTKTDIFAAA
                     ISHAGISDITSYWGEGYWGYSYSALATANSYPWNARDIYVEQSPLFHADKINTPILFLH
                     GSVDTNVPVGESIQMFTALKLLGKPTAFIQVNGQNHQILDYKKRAEWNKTIYAWFAKYL
                     KEQPEWWEALYPPKSL"
     CDS             complement(12246..14105)
                     /locus_tag="ctg27_12"
                     /transl_table=11
                     /translation="MRKAIIMLSLFLCHFTLVYGNNQGKQEYILVLNSVNYDEVWTNGV
                     YQSIYNTFNGSQYAIRTEELMVPTIANADEAEAKRNSLLEKYPIRPKVVVFIGDPGWIV
                     YRSLFDSEWKEVPVLICYSRKTMPGCIENLLSRNISDKELVPASQMLKGYNITTLYQPF
                     YMKETIELMQRIQPEIKNIAFISDNRYISLCAQKEVEQAMADYYPSLKLDILTTTRLST
                     EQLLDTISRYNKETGILYYSWFSKQVQENNYLNDNIQRIVYGFAHNPVFTVADLQAENG
                     NFAGGHYISLPDFSEEVIHTLQQIVDGTPARDIQPHNGGEPQTYLNYRHLKLHNTDSNL
                     YPRNAVYYQRPPSFYEQNKLAIICIIALACAIVIILVMRLRFYWQVQQEIREREKAEEA
                     NRLKSAFLANMSHEIRTPLNAIIGFSTLLANEENLEERQEFIKIIENNNELLLQLINDI
                     LDLSKIEAGTLEFIYSDVDVNSLLTEIEQSSRIRNRHPEIQISFEERLPQCIIHTERNR
                     LTQVINNLLTNSMKFTTRGSIRFGYRQEGNRLRFYVKDTGCGIPADKIDSVFGRFVKLN
                     NFQQGTGLGLSICKTIVEKLGGEIGVESKEGVGTLFWFTIKVE"
ORIGIN
        1 tcaacctact ttatcgataa gacatttagt agtcaactaa aaacgttaac atacagttcg
       61 tttaaaataa ataatcgttc gacaatcatt ctttatgcat ttaacagcta tcgaataatc
      121 attcgacaat tgtcgaacga ataaagaatg attgtcgaat gatttttttt ctagaagcga
      181 aatttatttt tagaagtatt tcgatttatc agggagaaac aagttatatt tgaacaatta
      241 atatcaatat aacctatgat cacacaatac gacctgtatg aaacaccttc acccaaaggg
      301 gaagacggta aaaaatcgct gcatgcccgt gtttgtccga aaaagactta caccagtcaa
      361 gagtttgtag aacatgtggc cgcctttgaa catctgccga agaatcagat tggcggggca
      421 cttgctgcca ttgtcgacga cctttgttat ctgcttgccg atggaaacat tgtggaatta
      481 ggtgatcttg gatttttttc tacttcattg aagtgcctga aggatacgga tgacgatgag
      541 gatgaaatca aaccgaaatc gatcgctttt caaaatgtac atctgagaat cagcagtgaa
      601 tttcgaaaaa gaatcaaaca tgagatgaag tttcaacgcg tgcattccct tacgcggaga
      661 caaaaaattg tcaattctac cgtgaaagag cggatgaaaa aaatggtctc tttcctcaaa
      721 ataaacattt gtattacccg aaaggaatat ataggactgg tcggattgac accttacgag
      781 gcgatgaatg aactgaacga ttttatcagc cagggtcttc ttcgccgtcg cggggcgggc
      841 aggtctgtgg tatatgttgc gggggaaaat ctgaaggtag aataattata taggtaatat
      901 tttaccctgt aatccctatt tatggttaga aatgagctcg ttttacatat aaataggtat
      961 tgcctgtgcc tttccgtggt tttacctttg ccgtatcaat taagttttac tattagtata
     1021 aatcgtcctg accaaaatcc gatttgttga tttttatgta cacctattat ttaaggtaaa
     1081 tacccatgga agggagtttt tttattggtt gtccctttca tatataaaag ggagccatcc
     1141 tgtgaagaat ggctcttttt tatttatcaa agaaagcaat ttttgcaaat attgtttatt
     1201 ccaatgatca attttcccga ttataacaca gaataggtag taggaagctc tttttttact
     1261 atataatagg tattgtgtac tccccttgac ggctctatct ttgcaacata gaaaaaagta
     1321 acactattag tataatcgct atatcaaaac cttttgctaa ttatgtaagc atataagatg
     1381 attaaacgtg tgtcggaaat tttttattgg ttgtttccgg cataaaaaag ggactctcct
     1441 gcgaaggatg gttccttttt tatttttttg atattattta taatccttcc tgtttgatac
     1501 ctatatcagg cgatacgttg cactatatct accgttttag taactatttg tagggatttt
     1561 ggccgttggg aatacatgat gtttttgttg attgtttcgc atgccatata aataacgtac
     1621 ctttgcaccg aaattaaaac cgaagaaaac aaaataaggt atgaagtttg aaaacgagaa
     1681 ctgggcgcag ttcaaaggcg aaatttggaa aagagagatt aacgtaaggg attttatcca
     1741 gaacaactac aaaccttacg aaggggacga ctctttcttg aaagactcct cagataagac
     1801 gaagaaagtt tgggataaat tgaccgaaat gtttaaggtt gaaagggaga agggtgttta
     1861 cgacgctgaa acaaaatatc ctcaaggtat agatacttac ggaccaggtt atattgacaa
     1921 agaaaacgaa gtaattgtcg gcctgcaaac cgatgccccc ctgaaacgcg gtatttaccc
     1981 gaaatgtggt acccgcatgg tggaaaacag tctggaagca tatggctaca aactggaccc
     2041 gatgacaaaa gaaatcttca cgaaatacag aaagacgcat aacgaaggcg tattctccgc
     2101 ttatacagat gaaatgcttg cagcgcgccg ttccgctatc atcaccggcc tgccggatgc
     2161 ttacggacgc ggacgtatta tcggtgacta ccgccgtgta gcactttacg gtactgaaat
     2221 cctgatcgct gaaaagaaac attatctgaa aagactcgat attcaggaac tgaccgaaga
     2281 gatcatccag agccgtgagg aaatatccga acagatcaag gcgctgaagg ctttcgaaaa
     2341 gatgtgtgcc ggttatggtt tcgacgtgac caagcctgca aaggatgcac gcgaagcggt
     2401 tcagtttgtc tatctgggtt atctggctgc ggtgaaggac caggatgggg ctgccatgtc
     2461 gttgggacgt acttctactt tccttgatat ttatattgaa aaagatatcc gcgaaggcaa
     2521 gctgacggaa gaagaagctc aggagctgat cgatcagttt attatcaaac tgcgtatcgt
     2581 ccgtttcctt cgtactccgg aatataacga cctgttctcc ggtgatcctg tttgggtaac
     2641 cgagtctttg ggcggacagg gtgtcgacgg ccgttcattg gtgacgaaga cgtcttaccg
     2701 ttatctgcat acattatata acctcggccc ggcaccggaa cccaacttaa cggtactgtg
     2761 gttcaacaac gctcctgaaa actggaaacg tttctgtgcg aaggtttcta tcgatacttc
     2821 cgctatccag tatgagaacg acgatctgat gcgtccggat tatggagatg attatggtat
     2881 tgcctgctgc gtgtctccga tgaagatcgg taagcagatg cagtatttcg gggcacgtgc
     2941 caacctggct aaatgtttgt tgtatgccat caacggaggg cgcgatgaaa gatcaggtgt
     3001 acaggtggct ccgaggtttg aaccgatcac cagcgaatac ctggattaca acgaagtgat
     3061 ggagaaatac gaacagatga tgcgctggct ggctaaagtt tatgtgaacg cactgaagat
     3121 catccattac atgcacgata aatatgcata tgaagcattc gagatggctt tgcatgacgg
     3181 ttcggtagaa cgtatccgcg caacaggtat tgccggcctt tctatcgttg ccgactcatt
     3241 ggctgctatc cgcgatacga aagtaaaagt gatccgcgac gaacgtggcc tggctgtcgg
     3301 tttcgaacgt gaaggcgatt atgttccttt cggtaacaat gacgatcgta cagatagtat
     3361 tgctgtcgat atcactgaaa agttcatgga atatctgcgt cagcaccaga cataccgcaa
     3421 cgccactccg acacagtcta tcctgactat tacgtctaat gtcgtatatg gaaagaaaac
     3481 aggtgcaact cccgacggtc gcgaaggtgg tacgccgttt gctccgggtg cgaacccgat
     3541 gaacggacgt gataccaaag gcgctgttgc tgcactggct tctgttgcta aactgccgtt
     3601 ccagcatgca cacgacggta tctcttatac attcgctgtt tctcctgcaa cgttaggaaa
     3661 agaacgtgat attcagatcg ccaatatggt cggcctgctg gacggttact ttactcctga
     3721 cggcggacag catctgaatg tgaacgtatt cgacaaggag ctgttgctcg atgctatgga
     3781 gcatccggaa aactatccgc agttgacaat ccgcgtatcg ggttatgcag taaactttgt
     3841 gaaactgaca cgcgaacagc agctggatgt gatttcaaga acaatcaatc attctttgta
     3901 attgaaagtt ggaaattaaa ggaaacatac attcactaga gagtttcggg accgttgatg
     3961 gtcccggaat tcgttttgtt gtctttatgc agggttgtcc gctccgttgc ctgtattgcc
     4021 acaatccgga tacctgggat agcaaaggtc ttgccaaata tcagatgacg cctgaagaat
     4081 tattggctga ggttttacga tataagaact ttatcgccaa gggaggcgtg actgtcaccg
     4141 ggggagaacc tttattgcaa gctgaatttc tcagggagtt tttccgtctt tgccgggaag
     4201 ccggtattca tacggcgctc gatacatccg gctatatctg cacaccgaaa gccctggcgg
     4261 ttctggaata tgccgacctg gtcttattgg atataaaaac catcgatccc gacctgcatc
     4321 cccgtctaac ggccgtgaaa ctggataata cgttacgttt cctggacgaa ctggaaaaac
     4381 gcggtgtccc ggtttggata cgccatgtca ttgtgcccgg actgacggat aatgacgaag
     4441 ccttggataa actggccgaa tacatcagcc attatacggt tgtacagaag gcggaactct
     4501 tgccttatca cacgatgggc acatataaat acgaggcaca aggtctcgac tacaaactga
     4561 aagaggtaga acctttatcg gccgaacgtc tggcaaatgc caaagaaata tttaagaagc
     4621 acggtataac catctgataa tttacctata atcaggtata tttttattgc tctaaaaaac
     4681 atagttttgt cccatattgt tactcaaata aaagtaggaa tgaatatgga acaacatcat
     4741 catgatcatc accaccacga aataacctct ttgaacaagg ctttcattat aggtatctcc
     4801 ctgaacctgg cttttgtcgt agccgaattt acggctggct tctggtataa ttcattagga
     4861 cttctgtcgg acgcagggca taacctggga gatgtggcca gcctggtact ggctatgctg
     4921 gctttccggc tggctaaggt gcacccgact tgcagctata cctatggata taagaaaagc
     4981 actgtactcg tatcccttct gaatgcggtc atcctcttgg tggccgtcgg gattattatt
     5041 gctgaaagta taggaaaatt gctgcatccg cgtccggttg agggtgatgc gatcgcttgg
     5101 gtggcaggta tcggagtcgt tataaatgca cttacggcat ggcttttcat gaaggataag
     5161 gataaagact tgaatgtgaa aggtgcttac ttgcatatgg ctgccgatgc actggtatcg
     5221 gtcggcgtgg ttgtctccgg aattgttatt gcccataccg gatggtatat catcgacccg
     5281 attatcggcc tgttgattgc gttcgttatc attgtttcta cctggggact gctgcgcgac
     5341 agtatccgtc tctctctgga cggtgtgccg gcgggaacgg acatcgataa ggtggaaaag
     5401 acgatacatt cggtcgaagg cgttgaaggc gtccatcatc tccatatctg ggcgatcagt
     5461 acgaccgaaa cggcacttac cgcccatgtt tccgttgcgg atatttcaga aatggaacgt
     5521 atcaaacagg agataaaaca cgaccttcag catgtgggaa tccagcatgc tacgctcgaa
     5581 tttgaaacgt cgggattcaa gtgcgatggg cactgttgct cagactgaaa catgtatatt
     5641 ataaacctga tttactgata ctcaaagatt ttgtctatga ctgcataaaa cctttcgatt
     5701 ggattttttg ttcttacctc gaatcggcaa cttatctttg catcagtaac aaaaacaaaa
     5761 tagtaataac gattaaaata aaaattctat ggaacctatt atcaattcac aagcacccga
     5821 gtttaaagtt caggcatacc acaacggtag tttcaaaact gtaagcagcg acgacatcaa
     5881 aggcaaatgg gcgattttct ttttctaccc ggctgacttt acatttgttt gtccgaccga
     5941 gttggtagat atggctgaca aatatgacca gttccaggca atgggtgtag aagtttactc
     6001 tgtaagtaca gattcacact tcgtacacaa agcatggcac gatgcttctg aaacgattcg
     6061 taagatcaaa tacccgatgt tggcagaccc gacaggcgta ttgagccgtg cattcggtgt
     6121 aatgatcgaa gaagacggta tggcttaccg cggtacattc ctggtaaatc cggaaggaaa
     6181 gattaagctg gcagaaatca acgataacgg tatcggccgt aacgccgacg aactgcttcg
     6241 taaagtagaa gctgcccagt tcatcgccga acatccgagc gaagtttgcc ccgccaaatg
     6301 gaaaaaaggt ggcgaaacat tgaaaccgag catcgatctg gtcggtaaga tctaatagta
     6361 aaactggagg ccggcaacac attgtcggcc ttttttatct aaacaaatat cagttgttct
     6421 attcataatt aaaataaagg attcaactat gttagattca tcaatgagaa atcagttgtc
     6481 cggtatcttt agcggattga cgaacgaata tatatttgat atacaagttt ctcctgaaca
     6541 tgaaagcagg aaggaattat tggaattgct gaacgatgtg gcttcctgtt ccgataagat
     6601 caccgtacag gtggcagacg gcgaaggcct ggagttctct ctgctgaaaa acggggaaaa
     6661 aaccggtatt aaattccggg gcgttcccaa cggacacgaa tttacttcgt tgctgctggc
     6721 tatcctgaac agtgacggca aaggcaaaaa tattcccgat gaaagtattt gtaaccgtgt
     6781 gaaggccctg aatggcccag tcaaactgac tacatatgtt tctttgacct gtaccaactg
     6841 tccagacgtt gtacaggctt tgaatgccat ggctacgctg aacccggaaa tctctcacga
     6901 aatggtggac ggtgcgatca accaggaaga ggttgctgcc atgaaagtgc agggagtacc
     6961 ttccgtattt gccgacggta aactgatcca tgtaggtcgt ggagactttg gcgaactgct
     7021 tggcaaactc gaagcgcagt atggcgtgaa agaggagaac ctgccggtgg tagaaaagaa
     7081 ctacgatgtt atcatcgtcg gcggaggtcc tgccggaagt gcgtcagcta tctatactgc
     7141 ccgtaaaggt ttggcggtgg ctgttgtggc cgaccgtatc ggcggacagg tgaaggaaac
     7201 tgtcggtatc gagaatatga tttctgtttc gcagacgacg gggcagcagc tggctctcga
     7261 cttgatgtcg catatgaaag attatccgat cgatatcctt gaacaccgcc gtatcgagaa
     7321 ggtggaagtc gaaggacgcg aaaagctgct gacaacctct accggcgaaa aactgatagc
     7381 cccggccgtt atcgtagcaa ccggagccag ctggcgcagg ttgaatgtcc ccggagaatc
     7441 cgaatatatc ggacgcggtg tcgctttctg tccgcattgc gacggtccgt tctataaagg
     7501 caagcatgtg gctgttgttg gcggaggaaa ttcaggcgtt gaggcggcta tcgacctggc
     7561 aggtatctgt tcaaaagtga cgcttctcga atttgccgat gagttgaaag cggatcaggt
     7621 cttgcaggat aaggcaagaa gccttccgaa cgtggagatc tttatgcatt cccagacgat
     7681 ggaggtactg ggtaacggtg aaaaagtgac cggtatccgt ataaaggacc gtaagacaga
     7741 ggaagtccgc aacatcgaac tggatggcat ctttgtccag atcggcctgg cagccaacag
     7801 cggtccgttc cgtgaggtgg tagatacgaa ccgtcagggt gagatcgtga tcgatagcca
     7861 ttgtcgtaca agtgttccgg gtatctatgc ggccggagac gtatcgactg tcccttataa
     7921 acagatcatt atttcgatgg gcgaaggggc caaagcagcc ctgacagctt tcgaagaccg
     7981 gatgcgggga atgttataag ccgcagaact ttccggaagg cataaaaaat aatacccggg
     8041 tataaatcga ttcagaagcg tttctatgtc ggtttatatc cgggtattgc tatctttgca
     8101 agattcattc taatctatac aattatgtcg atgcatgaaa ttgaaagtct ggtggaaagt
     8161 tctgtgataa cagttgccac tgcttctcct atccctcctt tagcccgaaa catttgtttc
     8221 aatctttacc agctccagaa tcaactggat tgtggatata ctgtcctgcg ggtacgggaa
     8281 gaactggaaa aactcggtta tctcttcctt ctgcctccgg agcaattacc cgagccggaa
     8341 cgtagtgcag ccctgaaact caacgaagaa ggtggctttt tgagtgacgg aacttatttc
     8401 gaccaccgtt cggatcgttg ctgtgtcacc gcaggatcgt tgctgtggac gaaactgatc
     8461 gatctcggca tccttccgga atcggcaaag accgaacttc gtgaactcga tcctttggaa
     8521 ctggccgaac ttatcatccc actggcttca aaggtgctcg ccgggggaga taaagaagat
     8581 gataattatg ctaatgccgc tgatacgctg ggattttggt atgccttttt ccccttattc
     8641 tgtcagatgg cggggatgga cgaggaggat gcgccggaac cggagcgaat ccgggcgtta
     8701 cttgaaatgc tggctgttcc cgaatcattt gaagtacttg cgactgatga gattggcaag
     8761 gagttggatg actttgaaga agaagaaatg ccttttctct ccggttggag cgctccgtat
     8821 aatgaatgga agaacaagaa caatacaggg gatttatccc tggagttttg caaatcgatg
     8881 gtccacgatt ctattttgaa gagaaagttt gttgaggccg atcgttatgc gtccgctatg
     8941 gaagaaggac cggaacttaa ccggcttttc catcgttgtt tggttggcat gtcttactat
     9001 gaatgggtga aaatacaagg aataaaaatc ccgattatag aaagtgttct ctctcaggaa
     9061 gaggcaaaag aaggttttga acgtgtagca gacttgtcgg tatcgtctga taatgtgcag
     9121 tgtgcccgac tgggtatttt cagaatcctt gctttacagg gtgaatatgc cgaatcggtt
     9181 gagtatttga atgccgtata ttttaaggca ctcgatgagt gtggtcaaaa atcgaaagaa
     9241 ctactggggc aatcgcaacg tgctgtgtta gtggtagtct attatcggat gctggaaatg
     9301 tctatacccg atagttttcc tgggaaaaag gaactgatgg ctcataaagc attgaacggt
     9361 tctgatcttc gcaaatcccg ggaaatactc agtttattgc ttattgaaaa atccgaacat
     9421 gcctatgcat ggcaacaggc cttctctttt tgtgatgagc tgataaaaaa gtatggattc
     9481 tgaaatcgtt agtgctgatg aaatatgtgt tatttgcatc ggggttcgat gtaacgttgc
     9541 atcagctgtc aatgtaacgt tacatcagct gtcaatgtaa cgttacatca gctgtcgatg
     9601 taacgttgca ctgcatgtcg atgtaacgtt gcgtcgcatc ccgacgcaat tcttttacag
     9661 actttttggc ggatagagag cttcccacca ttccggctgc tctttcagat atttggcgaa
     9721 ccaggcatag atggttttgt tccattccgc ccgtttctta taatccagta tctgatgatt
     9781 ttgtccgttt acctgtatga aggctgttgg cttgccgagt agtttcaggg cagtgaacat
     9841 ctggatactt tctcctacag gtacgtttgt atcgacggag ccgtgcagga acaggatcgg
     9901 cgtgttgatc ttgtcggcat ggaacaaggg gctttgttct acatagatat cccgtgcatt
     9961 ccaggggtaa ctgttggcgg tagccagtgc actgtaagaa tatccccagt aaccttctcc
    10021 ccaataactg gtaatatcgc tgataccggc atgtgagatg gcggcggcga agatatcggt
    10081 tttagtttgc aggtactgtg tcataaagcc gccgtaagag gcgccgatgc agccgatctt
    10141 tttggcatcc acgaaactgt gttcttcaca aaactttttt gttccttcga tgatctcgtc
    10201 tcccgtacgt tttccccagg cattgacgtg gcgtgcggaa aattcctgtc cgaaaccggt
    10261 ggcaccgctg ggttgtatga tataaaccac atatcccagt gcagcatagg tatgcgacgg
    10321 ataacggttt tcgagtgagc gttccgtcgg acttgtccca ccgtaataat taacgatcag
    10381 cggatatttc ttgcttgggt cgaaatgcgg cggcagatag taacgtccgt agattgtatc
    10441 tccggcagcc gcctggaaat tccagtcgtg tacttcgccc agggtaatat ctttcagaat
    10501 gtctttggac aagtctttca ggcagacaga ctctttctct ttctttttca gattcatgga
    10561 gtagagtcgt tgtgagttgg aggcactttc gccgaaataa acaagttcgg gggtattttc
    10621 agcaattgtg aaatccgata atatatcttc tttcagtgga accggactga tctttccgtt
    10681 tgctgggttg agcgtataca ggcggacaca gtctttgtct tctccttgca ggtagatttg
    10741 tttatctccg gtattccatg taaatgattg gatagacgga ttaaaatcct tgcttacggc
    10801 tgtcgcctgc ttattggaga ggtcgtagat gaacaactgt ccgtcagcca ggttggatgt
    10861 ttgttccgga gcaatattca agccaatttt gttgaatgcc tctcccgaac cggaaacagc
    10921 cagttgcttt ccgtccggtg aaaaactggc atagttgatg aacggatctt ccaggagtgt
    10981 atcaacctgc ctgttctgca aatccatccg gtaaaggatt tttgtgctga acggacgctt
    11041 cgtcagttcg cgccggctgc tggtgaacag cagataacgg ccatctttcg aaatgtcgtt
    11101 aagcgaagtg gaattgtggc cgtaagtgag gcgttcgaga acacccgttg ccaggtcata
    11161 tttgtgtagg aaggaacggt tgcgccatcc cggctgacgg tcgtcgggca cgagtatttc
    11221 ttccatgtct ttgtcttttt ccggcccttt ctcggagatc gtgaagatca gaaaatcttc
    11281 tgtcggggca atactgaacc agccatcggg caaattctgg gagaggattg tttcggcttt
    11341 tgttaccgga tcgacggtca ccagttcttt tccttgtaat cctttacggg tataataaag
    11401 acggttgctt tggggcatcc agctgaaatt gttcgtactg ctttccatca gtacctgtcc
    11461 gttggtttta tgggtaatct gctgaaaata tgcggtctgt ccgccgggat aagtagtctg
    11521 ataggaggta agcagatatt ttccgttggg ggagaggctg acagagcgga aacgtgttcc
    11581 gtcgaacacg tcgctgatcg tatatctttt ttccggatcg gtggtagccg tgataacagc
    11641 ctctttttcc gtatcgaacg aaactttcag ggtgccggct ttatcgcttt cggctaaata
    11701 tttgataacg atttcgtaac gatgaggttc cagtgacagg gaaacctttc cgtcgggggc
    11761 tgtttgtttt tcgttattta catagacctc gtatgtttcc gggcctttaa cctgcaaagt
    11821 cccttttaca taccggtcgc tgttcagata gaaagaggcc agtccgatat aagaagattg
    11881 gttgccggcc ggaagtgtac tttctccgtc ggcatttgct tccagcaatt gtgtactttg
    11941 acgtacattg ctaaacggaa cggctgtttt taataattct ttttcggtga atttcttact
    12001 gtttacgtcg aggctgtctt tcaggaacgg ctttttcact tcatacgggc cggcatatct
    12061 gaattgcttg actatgacct cctcagcgaa aaggttatag caggaacaga tagctgccag
    12121 aagcaatagg tttcttttca tggcgaataa aatttgatgt ttcctgcaaa ggtatttatt
    12181 tttttgacag ggagacctat acttttgaaa tcctgaaatg tattgtaaga aatgaaagaa
    12241 gaactttatt caaccttaat agtaaaccag aataaagtcc ctaccccttc tttcgactcg
    12301 acacctatct ctccgccgag cttttctacg atggttttgc agatggatag gccgaggccg
    12361 gttccttgct ggaagttgtt cagtttgacg aaacgtccga agactgaatc tatcttatcc
    12421 gcagggatgc cgcatccggt gtcttttaca tagaaacgca gcctgttgcc ttcctgtcga
    12481 taaccgaagc ggatacttcc ccgggttgta aacttcatag agttggtcag caggttgttt
    12541 atgacctggg tcaggcggtt tcgttccgta tggatgatgc attgtggcag acgttcttcg
    12601 aaagagattt ggatttccgg atgccggttc cggatgcggc tgctttgttc tatctccgtc
    12661 agtaaagaat tcacgtctac gtccgagtag atgaactcca gggttcctgc ctcaattttg
    12721 gagaggtcca gtatgtcgtt gatcagttgg agcaataact cattgttgtt ctcgatgatc
    12781 ttgatgaatt cttgcctttc ttccagattt tcttcattgg ctaacagggt ggagaagccg
    12841 atgatcgcat tcagcggggt gcgtatctca tggctcatgt ttgccaggaa ggccgatttg
    12901 aggcggttgg cttcttctgc tttttcgcgt tcgcgtatct cctgttgtac ttgccagtaa
    12961 aaccggagtc tcatcaccag gattatgact atggcacaag caagtgcgat gatacagata
    13021 atagccagtt tgttctgttc atagaaactc ggaggacgct gataatagac cgcattgcga
    13081 ggatagagat tgctgtcggt attatgtagt ttcaaatgcc ggtagttcag gtaggtttgt
    13141 ggttcacctc cgttgtgcgg ctggatatca cgagccggag tgccgtctac tatttgctgt
    13201 aaagtatgaa taacctcctc gctaaagtcg ggtagcgaga tataatgacc tccagcaaag
    13261 ttcccgtttt ccgcttgtag gtcggcaacg gtaaataccg gattatgggc aaagccgtaa
    13321 acgattcgtt gtatgttgtc attcaggtaa ttattttctt gaacctgttt agagaaccag
    13381 gagtaataca atattccggt ttctttattg taacgtgata ttgtgtccag taactgttcg
    13441 gttgaaagcc gggttgtagt gagaatatct aacttcagtg acggataata gtcagccatt
    13501 gcttgttcca cttctttttg tgcacacagg ctgatatagc gattatcgga tatgaaagca
    13561 atatttttta tctccggttg aatacgttgc atgagttcaa tcgtctcttt catatagaaa
    13621 ggttgatata aggttgttat attatagcct ttcaacatct ggctggcagg gacaagttct
    13681 ttgtccgata tattccggga aagaagattt tcgatgcaac ctggcatggt tttgcgtgaa
    13741 tagcagatta agacagggac ctctttccat tcactgtcga ataaggaacg gtatactatc
    13801 catccgggat cgcctataaa gacaactact ttggggcgta tgggatattt ttccagtaag
    13861 gagtttcttt tggcttcggc ttcatccgcg ttcgcgatgg taggaaccat cagttcttct
    13921 gtgcggattg catattgcga gccattaaag gtgttgtaga tagattgata gactccgttc
    13981 gtccagactt cgtcgtaatt aacggagttc agaacaagga tgtattcctg cttgccttga
    14041 ttattaccgt atactagtgt gaaatggcag aggaaaaggc ttagcatgat gattgctttt
    14101 cgcataaagc ctgtataatt tgaagtaaaa aagccgtctg aaagacttac tgtcggaaag
    14161 aggtaagtct tttagacggc tttaatgttg atgttttacc ctattgaata ataatttcgt
    14221 ctacgaacag ataggccgga ttacctgcgc cgccatgcca tgccggcagt ttgtcacttt
    14281 tgattatcac ttccacgtaa cgggctttta ccggatcgaa ggtaatttcc tgcggataga
    14341 tgccatcctt atcggtttgt ttcagggacg ggattgtttt ggataccact tccctgaagt
    14401 tcttaccgtc ttcggatacc tttacggtaa ctccggcagc ccccatgatc cagtcgcctt
    14461 taaccacatt ggtattgaaa gccaccttgc tgatttcgac cggctgtttc aggtcgatcg
    14521 ccgcatccag gtcttttccc tggaagccca gccaacggcc ggttttgtaa tttgtatcac
    14581 cggtcaggcc gtccgtcatt tcaggaccac ctttgaaatc gtatccttta ctcggag
//
