LOCUS       gnlProkkaFFIHKOFH_84    9343 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFIHKOFH_84.
ACCESSION   gnlProkkaFFIHKOFH_84
VERSION     gnlProkkaFFIHKOFH_84
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 18:25:46
            Original ID  :: gnl|Prokka|FFIHKOFH_84
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9343
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9343
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4910:9224]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4911..9224
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9343
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9343
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             302..880
                     /locus_tag="ctg84_1"
                     /transl_table=11
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSEESISMNSSPLARGEKVRVIKGPLTGLVGELVNVDGK
                     SKIAVRLNMLGCACVDMPVGYVEPIMAAV"
     CDS             945..1259
                     /locus_tag="ctg84_2"
                     /transl_table=11
                     /translation="MLLPGGGSAGCVYLDDLSALQRSIHEKINDLYSQRGETPEQDATL
                     CLAILQGYNVSMYANPEDEERKQAVLTRSLSLLDVLPPSLLKQQLSAVCHGMQELCEIN
                     "
     CDS             1277..3688
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg84_3"
                     /sec_met_domain="Poly_export (E-value: 7.6e-19, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAYPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             3699..4847
                     /locus_tag="ctg84_4"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             4911..5630
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_5"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.1e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             5651..6952
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208;
                     E-value: 2.8e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_6"
                     /sec_met_domain="CTP_transf_like (E-value: 1.4e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 2.7e-121, bitscore:
                     393.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.6e-63, bitscore:
                     203.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVRAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             6969..8093
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.4;
                     E-value: 1.2e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_7"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.5e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.8e-21, bitscore:
                     65.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIARGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             8103..9224
                     /NRPS_PKS="Domain: Aminotran_5 (30-344). E-value: 5.1e-34.
                     Score: 109.6. Matches aSDomain:
                     nrpspksdomains_ctg84_8_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 77.2; E-value:
                     2e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg84_8"
                     /sec_met_domain="Aminotran_5 (E-value: 2.3e-31, bitscore:
                     98.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGDIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKVSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTANTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        8193..9134
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg84_8_Aminotran_5.1"
                     /evalue="5.10E-34"
                     /label="ctg84_8_Aminotran_5.1"
                     /locus_tag="ctg84_8"
                     /protein_end="344"
                     /protein_start="30"
                     /score="109.6"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGDIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKVSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTANTFRICAL"
     CDS             9221..9343
                     /locus_tag="ctg84_9"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKY"
ORIGIN
        1 gttacttctt aggtaacgga atgattcatg gcgcaaagat ggacatattt atgaaaatac
       61 gcaaacaaaa atgaaattaa tttcttaaaa tgaatcaaaa gtcggcataa catacggaaa
      121 atgacaatat ccgtgttatg tctttttttt attccaattt atgaaaaccc ccttcacttc
      181 tgccttattt cctgaatacc agtcctcttc cgatgtttcc gttgaaaaaa gttccctgtt
      241 tcgcttgtcc tttgtttgtg agttacctaa gaagtaacgg ataaacatgg ggtaaaaaaa
      301 tatgatttta agaaaaaaga aatcactaaa tgctgggcct attaatggga caggggaagg
      361 cgtagcacac tcaaaacgct ggtatgttgc tttggttcgg atgcaccatg aaaagaaggt
      421 ttccgagcat ctggacaaga tgggtatcga gaatttcgtt cccgttcaac aggaattcca
      481 ccaatggagc gaccgtcgca agctggtcac ctccgtcttg cttcctatga tggtcttcgt
      541 acacgttgac cctaaggaac gcatggaagt cctgagtttt tctactgtca gccgttacat
      601 ggtgatgcgc ggcgagagta gtcctgctgt aattcctgac gagcagatgg ctcgtttccg
      661 tttcatgctt gattattcgg aagaatcgat aagcatgaac agttctcctt tggctcgtgg
      721 cgaaaaggtt cgcgtgatca aaggtccgtt gacgggtctt gttggcgaac tggtcaatgt
      781 ggatggtaaa agtaagattg ctgttcgctt gaatatgctg ggatgcgcct gtgttgatat
      841 gcctgtcggt tatgtagagc cgattatggc ggctgtttaa ggcaagggat atggatgcta
      901 ttattttaca agaaaatata gagggtttat taagtttggt acgtatgctg cttcctggtg
      961 gggggagtgc aggctgcgtg tatttggatg atctttcagc attacaacga tccatccacg
     1021 aaaagattaa cgatttatat tctcaacggg gggagacacc ggagcaggat gctaccctgt
     1081 gtttggccat ccttcaggga tataatgtgt cgatgtacgc caatccggaa gacgaagaaa
     1141 gaaaacaggc tgttttgacc cgttctctgt ctcttctcga tgttcttccc ccttctcttc
     1201 ttaagcaaca gttatctgcc gtctgtcatg ggatgcagga actgtgtgaa atcaactgaa
     1261 acttttttat ttgtcaatga aaatacaacg actttttagc attctactat tttgtttgat
     1321 gctgggaagt ggctcgctta tggctcagtc catgagtgac tcacaggtac tggaatatgt
     1381 aaaagacggc atccgccaag gcaaggaaca gaagcagctt gcttccgaac tagcccgtaa
     1441 gggtgtaacc aaagaacagg caatgcgtgt gaagcagcta tacgagcagc agaacaatgt
     1501 aaatacctcg aaatcaacgg gcacggacat caacgaatcc cgcctgcgtg aagagactaa
     1561 gaagaatact tccgatatgc tggaggatca tccgactact caggaccttg cccgtggtga
     1621 tcaggtcttc ggacgtaaca tcttcaatac ccgcaacctg acgttcgagc ctagtgtcaa
     1681 ccttgccact cctgccaatt accgtcttgg tcccggtgat gaagtcatca ttgatatctg
     1741 gggtgcgagc cagaacacga tccgccagca aatctctcct gaaggtacta tcaacattca
     1801 gaagatcggc cctgtcaacc ttagcggtat gacagtctct gccgccaatg actatctgaa
     1861 gaacgccctg aataaaatat ataacggtct gaataatact accgatccta cttccgacat
     1921 ccgtctgacg ttaggtaata tccgtactat tcagattaat gtgatgggag aagtcgtaca
     1981 gcccggtacc tacgcccttt cttccttctc taccgtcttc catgcgcttt atcgtgcagg
     2041 cggtgtgagt gatatcggta gcctccgaaa cgttcagttg gtacgcaacg gaaagaatat
     2101 tgccaccatc gacgtctacg aattcattat gaaaggcaac acacaggatg acatccgcct
     2161 acaggaaggt gacgttgtga ttgttcctgc ctatgatgta ttggtaaaga ttagcggcaa
     2221 ggtaaaacgt cctatgcgtt ttgaaatgaa gaaagacgag aaccttgcta ctctcattaa
     2281 atatgccggc ggctttgaag ctgatgccta cacccgttca ttacgtgttg tccgtcagaa
     2341 tggtgaggaa tacgaagtca acacagtcaa agatatagat tacaacattt ataaaatgcg
     2401 taacggtgac gtagtaaccg ccgaagccat ccttaaccgc ttcacaaaca aactggaaat
     2461 ccgtggcgct gtctatcgtc ccggtatcta ccagctcagc ggtaaactga acacgatccg
     2521 cgaacttgtc catgaagctc agggtctgac cggtgacgct ttcctgaatc gtgccgtcct
     2581 ctatcgccag cgtgaagacc tgaccagtga agttgttcag atagacatta agtctatcat
     2641 ggacggcact tccccaaacc ttgccctaat gaagaatgac atcctctaca ttccaagtat
     2701 ccatgacctg gaagaccggg gtaatgtcac agttcacggt gaggttgcct accctgattc
     2761 ctatccttat gcggataaca tgacacttga ggatctgatc attcaggccg gtggcttgaa
     2821 agaagccgcc tctactgtcc gtattgatat atcgagacga atcaagaatc ctcgtagtac
     2881 tgcggataat gatacgattg gtcagatgta taccttctct ttaaaggatg gttttgtaat
     2941 agatggtcag cccggtttta tccttgagcc ttatgatcag gtttatgtcc gtcgcagtcc
     3001 gggctatcag gcacaacaga atgtagccat tgaaggtgaa atccttttcg gaggaaatta
     3061 cgccatgacc agccgtgagg aacgtctttc cgatttagtg aataaagccg gcggtccgac
     3121 caattatgcc tatctgcgtg gtgcgaaact gacccgtgtg gctaacgcta gtgaaaagaa
     3181 acgtatgggt gatgtaattc gccttatgag caggcaattg ggcgaagcca tgattgactc
     3241 tttgggtatt cgtgttgaag atacttttac ggttggaata gatttggaaa aagccttgag
     3301 caatcctaaa agtaatgccg atcttgtctt acgtgaaggt gatgtgatct ccatacctaa
     3361 gaatactaat actgtaacta tcaatggtgc tgtcatggtt ccgaatacgg tttcttatat
     3421 gaagggaaag aatgtggatt attacctgaa tcaggccggt ggctgttctg ataatgcaag
     3481 gaagagtaag aagttcattg tttacatgaa tggtcaggtg acgaaggtta agggtagtgg
     3541 taagaaacag attgagccgg ggtgtgagat tattgtgcct ggtaaggcta agaagaaagg
     3601 gaacatagct aatattttag gttatgctac ttccttcagt tctttgggaa tgatgattgc
     3661 ttctattgct aatttgataa agaaataaat gacctattat gattgaaaag caatcttatc
     3721 aagaaccgtt ttctgaagtg gataaaagga aagatgatga aatggaaata gacttgatgg
     3781 ctatttttta taagattatt actgttcgtg gagtactatg caaagctgct ggagtgggag
     3841 taataattgc tatagtggtg gcattgagca ttcccaagca atatacagta aaggttaccc
     3901 tttctcctga aatgggtaat gcgaagggaa gtaatggttt agccggactt gctgcctcgt
     3961 ttttgggaga tggggctcta ataggggaaa gcacagatgc cttgaacgct tctctttcag
     4021 cagatattgt ttcttcaact ccttttttat tggaactttt agaaatggaa gtctccgttt
     4081 ctaaaaagga tgataaaatg actttggggt cttatctcga tgaagagtca tctccttggt
     4141 gggattatct tataggtttt ccgggcatag taataggagg agttaaatca ttattcggag
     4201 aagatacggt tcctgccagt ggagggcggc aaggaactat cgaattgacg aaagaagtaa
     4261 atgagaagat taattttctt aaaaagaaga ttagtgcatc cattgataag aaaaccgcca
     4321 taacgagcat tacggtcacc ttacaaaatc cgcagatcac tgcggttata gcagattctg
     4381 tcgttcataa attacaggaa tatattattg ggtatcgaac ttcaaaagta aaagaagact
     4441 gtgcgtattt ggaacggttg tttaaagaac gtcagcagga atattatgct gctcaaagaa
     4501 aatatgcgga ttatgtagac gcccatgata atgtggttct tcaaagtgta cgtgctgagc
     4561 aggagcgttt acagaacgac atgagtttgg cttatcagat atatagtcag gttgctaatc
     4621 agttgcaggt atccagagcc aaagtacagg aggaaaagcc agtctttgca gtagttgagc
     4681 ctgccgttgt acctttgaaa ccttcaggta tgggactcaa aatttatatt ttattatttg
     4741 tgttcctgtc cgtatctggt actctcgtgt gggtgttttt tggcaaaagt ctgctggcta
     4801 gcttgagaaa agaactgaaa aataaggaga tagaacagga taaatgatgc taaaacgtcg
     4861 tttacaacat tcttacatca attaaattca cttactatat tattaaacga atgatacgta
     4921 cagctatgat aatggctgcg ggcatgggaa cccgttttgg ccaatataca gaattgatac
     4981 ctaaagggtt cgtcaaagtg ggaggtattc caatgatagt tcgttctatt gatactttgt
     5041 tatcatgtga cattgagcga attgtaatcg gtacaggata taaacaagaa gtttatgaag
     5101 aattgaagac agactatcct atgcttgaaa cctgttttag tcctcgttat gctgaaacaa
     5161 atagtatgta tactttatat aatacgcggg agattctggg caatgatgat tttttattgt
     5221 tagagtcaga tttgattttt gagaaacaag caataatgag cttattggag tgtcctgcgg
     5281 cagatgcaat gctaataact ccagtgacaa agtttcaaga tcagtattat gtggaacatg
     5341 atgataattt tcgcctttct tcatgttctg tcaataagaa taaactaaac gctaaaggcg
     5401 aattggtcgg catccataaa ctatccggtt ccttttacaa aataatgtgt gctgattatg
     5461 cgagtattgt tgatgaacaa cccaatttgg gatatgagta tgaattacta cgaatatctt
     5521 gttctcaatc tcctgtttat gtgcataaag tagaagggct gaaatggtat gaaatcgatg
     5581 acatatcaga tttggaatat gcagagaaat atattgttcc gtattgttaa ttaaaataat
     5641 atatcaaatt atgagtaaga cagtttatat tgggatgact gcggatatta tgcatccagg
     5701 acttatccgc attattaatg aggctactaa atacggtgat gttataattg gtcttcttac
     5761 agataaagct attgcggagc ataaacgcct tccttatctg acctatgaac aacgaaaaga
     5821 ggtagttcag aatattaaag gcgtatgtaa agttgttcct caagaagaat ggagctatgt
     5881 tgagaatctc aaacgcatta aacctgacta tataattcat ggtgacgact ggaaaaccgg
     5941 gcctttacgt gaagaacgtg tgcgcgtatt tgaagtgatg aatgaacagg gaggaaaggt
     6001 tatcgaaatt ccatatactt tgggaattaa ttcatcttct ttggataaag atattaaggc
     6061 tataggtaca acccctgatg tacgtttaaa atcacttcgt cgtttgataa atgccaaacc
     6121 cgtagttcgt attttggaag ctcatgatgg actatgtggc ttgataattg aaaatcagga
     6181 aatattaaaa ggggataaga gggaagtatt tgacggaatg tggtctagta gccttacgga
     6241 ttcaaccagt aaaggtaaac ctgatattga ggcggttgat ttaactaccc gattgcaaga
     6301 tttgaataat attctggagt gtactactaa acctattatt tttgatggag atacaggtgg
     6361 taaaattgaa catttcgtat ttacagtacg cactttagaa cgtcatggaa tttcagctat
     6421 aataattgaa gataaagttg gattaaaaaa gaattcattg tttggtacag atgttattca
     6481 aactcaagat acaatcgaag gtttctgtaa taagatcaaa gcaggaaagg catctcagat
     6541 tactgatgat tttatgatta tcgctcgtat tgagagcctt atagcgggaa agccggtaag
     6601 tgatgcttta gagagagctt ttgcatatgt ccgagcggga gcggacggta ttatgataca
     6661 tagcaaaaat aagtcgggtg aagatataaa agaattttgt ttggcgtttc gaaaacagta
     6721 tgctcatgta cctatcgtgg ttgtgcctac tacatatgat catatttatg agtctgaatt
     6781 gtgtgattgg ggtgtgaata taattattta tgctaatcat atgcttcgtg ccgcttatcc
     6841 tgctatgatg aatgtcgcaa agataatatt agagaatgaa cgtgctttag aggtgcgcga
     6901 actgtgtatg cccataaaag aaatattgga actgattcca ggtactaaat aaaaagagga
     6961 atatcattat gttaagcgta gaaaaagttt atgaaacgtt tctgagtcat gacgttgatt
     7021 tttttacagg agttccagac tcattactaa aaaatatttg tgcctatatc acagaccata
     7081 cttcacgtga gaaacatatc atagctgcta atgaaggtgc ggctgtagga attgcttcag
     7141 gttattatat ggcatcaggt aaggttcctg tggtttatat gcaaaattcc ggcttgggta
     7201 atactgttaa tcctctgctg tctcttgcag atgaacaagt atacagtttt ccaatgcttt
     7261 tgatgattgg ctggcgtggt gaaccgggaa caaaagatga acctcagcat aaaaaacagg
     7321 gtgaggtaac tttagatttg ttgaaagcaa tgcggattcc ttatataatt cttgattcaa
     7381 atgagaatga tgcatttatt cagctccatg atatcataca atcagcaaaa actaagaata
     7441 ttcctcatgc aataattatt cggaaagatg tttttggcaa atataaactt caaaaagagt
     7501 tcggatgtaa ttatccttta tctcgtgagg atgctttgca aatagttgtg gattatctgc
     7561 ctgaaaattc agtggtcgtt tctactactg gcaagctttc tcgtgagtta tttgaatatc
     7621 gagaaatgaa agagcaaggt catgaacatg attttctcac ggtaggctct atgggacata
     7681 gttcatcaat ctctttgggt attgctatag caaagcaaga tagacctgtt tattgcttgg
     7741 atggtgatgg agcatttatt atgcatttag gggcaattag taacattggc gatttatctc
     7801 ctaaaaacta ttatcatatt ttgtttaaca atggtgctca cgagtctgta ggaggacagc
     7861 ctactttagg atttagttta gatattccgg ctattgcccg ggggagcgga tataagcata
     7921 cttatactgt ttgtacaaaa gttgaaattg aagaagcaat gaagcagctt ccaaagttat
     7981 gtggtcctgt tttgttggaa ataaaggtta agatagattc tcgggagaat ttgggacgtc
     8041 ccacgactac tcctatagag aataaggagc attttatgga ttttttaaaa taaatatatt
     8101 cgatgaaaat agaaagaaaa atattattaa atcctggccc tgccactact actgacagtg
     8161 taaaaatggc acaagttgtt ccggatattt gtcctcgcga gaaagaattc gcaggtatga
     8221 tgaaacaact tcgggacgat ttggtcagag ttgctcatgg gaatttggaa aaacatacag
     8281 ctgtattatt ttgtggctca ggaaccatca atattgatat atgtctaaat tctcttcttc
     8341 ctgaagacaa aagggtgctt atagtgaata atggggcata tagtacccgt gctgtagaag
     8401 tgtgtcaata ttatggtttg cctcatatta atttggaatt ttctgtttat gaacgtcctg
     8461 atttatcggt agtggaaaat gtgttacaag aaaatcctga tatagctatg gtttatacta
     8521 ctcatcacga gacgggtaca ggaattctga accctattcg cgagatgggc gatatagctc
     8581 ataaatatca ggctaaattt gtcgtcgata ctacttcttc tttgggcatg attccttttg
     8641 atatagagaa agataatgta gatttttgta tggcatctgc tcaaaaagga cttcaagcga
     8701 tgacaggtct ttcttttatt ataggcaatg aggaacagat taaggtttca aaaaaatatc
     8761 ccaagcgttc ttactattgt aatctttatt tgcagtatga gaattttgag agaacaggtg
     8821 aaatgcattt tactccaccg gtacaaacta tttacgccac tcgtcaggca ttaaatgaat
     8881 attttgaagt gggcgaagaa gctaagtttg cccgtcacaa aagagttttt gaggctattc
     8941 attcaggtat aaatgaaatt ggtcttaaaa gtgtaataaa gcgtgaatgg cagtcaggac
     9001 tggttgtctc agttcaatac ccagaagatc ccaactggga ttttgagaaa atacatgatt
     9061 attgttatga gcgtggattt acgatttatc caggtaagat atcgactgcg aatactttta
     9121 gaatctgtgc tttaggagaa atagaagtag atgatattga gaacttcttt aaagtactaa
     9181 aagctgcatt aaatcattat aacgtcacat taccgatgtc atgattgcag aaatattatt
     9241 gaagattcgt catttttatt tttcccttcg tggtatacac ttccatccgg aaagtgttat
     9301 ttctggagtg cctattcgta gctttcgctt agtaggcaaa tat
//
