LOCUS       c00040_gnlPro..        13437 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GACJGOEM_40.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:56:10
            Original ID  :: gnl|Prokka|GACJGOEM_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13437
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13437
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3437](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3437
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13437
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13437
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             3..3437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_1"
                     /sec_met_domain="PFOR_II (E-value: 4.4e-18, bitscore: 58.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.3e-71, bitscore: 232.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 5e-31, bitscore: 100.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.8e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.8e-08, bitscore: 26.1,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00014, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 8.7e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EYVDEWAAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTT
                     TYTASQGLLLMIPNMYKIAGEFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAML
                     AEGSVQEVMDLAGVAHLATIKSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEAL
                     AEFRARALNPMNPVARGMAENPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYG
                     LFDYYGAEDAERVIIAMGSVTEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVP
                     KTAKTIAVLDRTKEPGANGEPLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSV
                     FENLAMPMPKNHFTIGIVDDVTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNS
                     VKIIGDNTDKHCQAYFSYDSKKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLH
                     MYDVTRGLRKNGSFLLNTIWEGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLG
                     NRTNTILQSAFFRITGVIPVDQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTL
                     AVDPAWANLPDDAKAENNDPAFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYE
                     KRGVAAFVPEWNPENCIQCNKCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGM
                     TFRIQVDVLDCLGCGNCADICPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQH
                     LVDIKSNVKNSQFATPLFEFSGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGS
                     VPSTPYTTNENGHGPAWANSLFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPE
                     AKEVLKAWIENMYDADKTKELAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIG
                     GDGASYDIGYGGLDHVIASGKDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRV
                     RKKDLGLMATTYGYVYVAQIAMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAG
                     MGKSQEEEEKAVKCGYWHLWRYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASV
                     MKQYPAEAEELFKAAEENAKWRYNSYKRLARENWGAE"
     CDS             complement(3398..3547)
                     /locus_tag="ctg40_2"
                     /transl_table=11
                     /translation="MNSSGKKVVLFMLDRVHTIKNGNLLQDYRFIFIGYYYYSAPQFSL
                     AKRL"
     CDS             complement(3592..4455)
                     /locus_tag="ctg40_3"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRGEHRQLVDSW
                     IPKSEN"
     CDS             complement(4476..5300)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg40_4"
                     /sec_met_domain="BPD_transp_1 (E-value: 9.2e-29, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGMAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             complement(5297..6523)
                     /locus_tag="ctg40_5"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDTDDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(6823..7161)
                     /locus_tag="ctg40_6"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             7245..8540
                     /locus_tag="ctg40_7"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             complement(8682..11564)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 62.8; E-value: 1.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_8"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.6e-19, bitscore:
                     62.8, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKEMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDILEEQRD
                     KLEEQRDQLIQLSHQLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQR
                     RMLLLVQRNVNILLRLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAVARKKH
                     IHFSFDYMPDTDYRTLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIR
                     FTVANTGSMISAEHIRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQG
                     TIFTVDLPVQTCETVVSENSPAFSVPATSVTSTDAATSAVAGAPVTPATSGYSGSSSLN
                     DALTYEEEELEKSYDSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAAYGSEGIRKAMK
                     YVPDLIISDVMMPGMDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYI
                     SKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGD
                     SNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGY
                     EVGFSSPSYFTKCYREQFGESPTDLLKRKG"
ORIGIN
        1 ctgagtacgt agacgaatgg gctgccgcag gacgtaagaa catcttcggc gaaacagtat
       61 tggtacagga aatgcaatct gaaggtggtg ctgccggtgc agttcacggt tctcttcagg
      121 ctggtgcgtt gactactact tacactgctt ctcagggtct tctcctgatg atccctaaca
      181 tgtacaaaat tgccggtgag ttcttgcctt gcgtattcca tgtatctgct cgtacattgg
      241 cttctcacgc attgtgtatc ttcggtgacc accaagacgt aatgtcagct cgtcagactg
      301 gctttgcgat gttggctgaa ggctctgtac aggaagttat ggatttggct ggtgttgctc
      361 acttggctac tatcaaatct cgtgttccgt tcatgaactt cttcgatggt ttccgtacat
      421 ctcacgaaat ccagaagatt gaaatgttgg aaaatgatga tcttgctccg ctgattgatc
      481 aggaagcttt ggctgaattc cgtgcccgcg cactgaatcc gatgaatccg gttgctcgtg
      541 gtatggctga aaatcctgac catttcttcc aacatcgtga atcatgcaac aactactatg
      601 aagcagttcc tgctatcgta gaagaataca tgaatgaaat ttctaagatt acaggtcgta
      661 aatacggttt gttcgattat tatggtgcag aagatgcaga acgcgtaatt atcgctatgg
      721 gttctgtaac agaagctgcc cgcgaagcta tcgaccactt ggtagcaaat ggcgaaaaag
      781 tgggtatggt tgccgtacac ctgtatcgtc cgttctctgc taaacacttc ctggctgctg
      841 tacctaagac tgccaagact atcgcagttc ttgaccgtac taaagaaccg ggcgctaacg
      901 gcgaacctct ttaccttgac gttaaagact gcttctacgg cgcagaaaat gctccggtta
      961 tcgttggcgg tcgctacggt ttgggttcaa aagatactac tcctgctcaa attctttcag
     1021 tattcgagaa cttggccatg ccaatgccga agaatcactt cactatcggt atcgtagacg
     1081 acgttacttt cacttctctt cctcaaaaag aagaaatcgc tttaggcggt gaaggaatgt
     1141 tcgaagctaa attctacggt ttgggtgctg acggtacagt aggtgctaac aagaactctg
     1201 taaagattat cggtgacaac actgacaaac actgccaggc ttacttctct tatgactcta
     1261 agaagtcagg tggtttcact tgttctcact tgcgtttcgg tgatactccg atccgttcca
     1321 cttatttggt aaatactccg aacttcgttg cttgtcacgt tcaggcttac ctgcacatgt
     1381 acgatgtaac tcgtggtttg cgtaagaacg gttctttctt gctgaacact atctgggaag
     1441 gtgaagaact ggctaagaac ctgcctaaca aggttaagaa atattttgca cagaacaaca
     1501 tttccgtata ctatatcaac gcaacacaga ttgcattgga aattggtttg ggtaatcgta
     1561 ccaacactat ccttcaatct gcattcttcc gtatcacagg tgttattcct gtagaccagg
     1621 ctgttgaaca gatgaagaaa ttcatcgtta agtcttacgg taagaagggt gaagacgttg
     1681 ttaacaagaa ctatgctgcc gttgaccgtg gtggtgaata caagacttta gctgttgatc
     1741 ctgcttgggc taacctgccg gatgatgcaa aagctgaaaa caacgatcct gcattcatca
     1801 acgaagtagt tcgtccgatc aatgcacaag atggtgactt gctgcctgta tctgcattca
     1861 agggtatcga agacggtact tggtatcaag gtacttctaa atacgaaaaa cgtggtgtag
     1921 ccgcattcgt tcctgaatgg aatccagaaa actgtatcca gtgtaacaag tgtgcatacg
     1981 tttgtcctca cgcttctatc cgtccgttcg tactcgatgc tgaagagcag aagggtgcta
     2041 agttcgaaca attgaaagca gtaggtaaag tattcgacgg tatgacattc cgtatccagg
     2101 ttgacgttct cgactgtctg ggttgcggta actgtgctga catctgtccg ggtaatccga
     2161 agaagggtgg caaagcattg acaatgaaac acctcgaaag ccaattggct gaagctgaca
     2221 actggactta ctgtgctgaa aacgtgaaga ctaaacaaca tcttgttgat atcaagtcta
     2281 acgtgaagaa ctcacagttc gctactccgt tgtttgagtt ctctggtgct tgctctggtt
     2341 gtggtgaaac tccgtatgtg aaattgattt ctcaattgtt cggtgaccgt gaaatggttg
     2401 ctaatgctac cggatgttct tctatctact ctggttcagt tccttctact ccgtatacta
     2461 cgaacgaaaa cggtcacggt cctgcttggg ctaactcact gttcgaagac ttctgtgaat
     2521 tcggtctggg tatggaattg gctaacgaaa agatgcgtgc tcgtatcgtg aagttattca
     2581 acgaaatcct tgctgccgac aacgcttcac ctgaagcaaa agaagtgctg aaagcatgga
     2641 ttgaaaacat gtacgatgct gacaagacta aagaattggc tcctcaagtg aaagcagtga
     2701 ttgaagaagg tctttctcac ggatgtccta tttgcaaaga actgaaagga ctgactcaat
     2761 atcttgtaaa acgcagccag tggatcattg gtggtgacgg tgcttcttac gatatcggtt
     2821 atggtggtct tgaccatgta atcgcttccg gtaaggacgt taacatcctc gttctggata
     2881 ctgaagttta ctctaacaca ggtggtcagt cttctaaggc tactccggta ggtgctatcg
     2941 ctaagttcgc tgctgctggt aagcgcgtac gtaagaaaga cctcggtctg atggctacta
     3001 cttacggtta tgtatatgtt gcacagatcg ctatgggtgc tgaccaagct caaactctga
     3061 aagctatccg tgaagctgaa gcatatccgg gaccatcttt gattatcgct tacgctccat
     3121 gtatcaacca tggtctgaaa gcaggtatgg gtaagagcca ggaagaagaa gaaaaggctg
     3181 ttaagtgcgg ttactggcac ttgtggcgtt acaacccggc tctggaagaa gaaggcaaga
     3241 atccattcca attggatagc aaagaaccga actgggaaga tttccaaggt ttcttgaagg
     3301 gtgaagttcg ttacgcttct gtaatgaaac aatatcctgc tgaagctgaa gaactattca
     3361 aagctgccga agaaaacgct aaatggcgtt acaacagcta caaacgtttg gctagagaaa
     3421 actggggtgc tgaataatag taatacccta taaatataaa acggtaatct tgtagaagat
     3481 taccgttttt tattgtatga actctgtcca acataaacag tactaccttt ttcccactag
     3541 agttcatgtc tattttatat ttaaaattaa gaataacaat gcttcaatct attaattctc
     3601 tgacttcgga atccaactat ccaccaactg ccgatgttca cccctccatt tgcgggctat
     3661 ttcttcttca tccatcctgg catccttcat agctgtcata aaagagctaa gttcttctgt
     3721 cgttagtttg atgttgccaa agaattcggc agcaaacgga tctttctcac tgaatccttt
     3781 ccatgcaata gcatgtattt cttccaagtc tccgtatact ttcttcggat catccaagaa
     3841 tttcaagtca aactggtcga acatccaatg cggtgtccac cccgtaatga caatccattc
     3901 tcctttgtcc atcgcttttt tcaaagaagc cagcatggtg gaactacttg aagtcatgag
     3961 ggtataccca tcaagtccgt aagcagcaat ggccttatcg gtcgtcttca ttatccctgc
     4021 tcccgcatca attcctacta tttcagaaga gaaacggtct ttattagctt ccagctcact
     4081 aatagactgg atcgtaacat attgaggaac aactagtcct acacgggcct ctccatatac
     4141 ctcacccaga aattcaatac tgtctccata ctgatccata taatctttca tcgttattgg
     4201 taaccatgca tccagaaaca catctgattt ctttcctgac atagatacaa aaataggggc
     4261 aagatcagca ttttgcaatt caacctcata tccatgctct tccaatacca ccttagccaa
     4321 atgactcatg gcaatacctt ccagccaatt ggcataggct atttttactt tctttttctc
     4381 taagtctgaa ttagtacagg aagctagcaa aagcatagct gacaatacta ttcctactat
     4441 tttatatatt ctcatacgta ttttatcctt tccgtttagt tcttattttt tcgtcctgcc
     4501 attccttgcg tgatacggtc taagatgata gctaaaataa caactgctat accaccttca
     4561 aacccaagtc cgattttcat ttgggtaata cctttcaata caatttctcc cagaccaccg
     4621 gcagcaatca tggcagcaat tacaaccata gaaagcgaca tcattattgt ctggttgaca
     4681 ccagtcagaa tggtgggcaa cgccaaagga agctgcactt tatacaataa ctgccaacgg
     4741 gtagctccga acgaacggga ggcttccact acatttttag gaacttgccg gattcccaat
     4801 ccggtaaggc ggaccacagg aggcatagca aagataatgg tggcaaacac ccctggcact
     4861 gctcccaatc cgaaaaacaa aacagcagga atcagataaa caaaagcagg catcgtctgc
     4921 atcaagtcga gaacaggacg gagtattttc tctgcacgcg aactgtttgc cgtccatact
     4981 cctaaaggta caccaacaat cagggccaga caggtagatg aaaaaacgag agccagggtt
     5041 tgcatagtag cctcccaaaa tcccattcca tagatcagta ataatcccaa tgcggtgaaa
     5101 attgccatac cgcgtcctgc tttcatccat gcgagtgcag caagtaccaa aatggttata
     5161 taaaaaggta ttccgaaaag tatgtgttgg aatcctataa taaaactacc gatgcccgca
     5221 ttcacggcat caaagaaagt ggaaaaatgt accatcatcc aattgatggc catctctata
     5281 tattgtccta tatttatcat aaatctattg cgttttgaat tatttcgttt atttcttctt
     5341 tatctttccc ggtcacttcg atgattaagg atgaaagcgg gattgttcct aaaaactcgc
     5401 gcgtctcatc aatcacccat accggcgaat tgctctttgt cattagagga agtatatcct
     5461 ccaacaccgt atcctccaac acagaatgta cttctgtacg cacaatcgtt tcaatggatt
     5521 tttcctgttt gctacgtaac ttaagcaagt cgttcagacg tacttctccg accagtttat
     5581 catcggtgtc tatgacaggt aatacggtga tattcttcgc acgcatctta cgaatcaata
     5641 cttcgggacc ttctttcttc agacgggcca ccaacggttt gtcaatcatt aaagaagagg
     5701 cggtaataat tttgctccta tccacgtttt caacaaaacg ggctacataa tcgttagccg
     5761 gttcagtcag gatttcctcc gaagtaccta cctgcaccac ttctccgtct ttcatgatgg
     5821 caatacggtc acctagctta attgcttcac tcaagtcgtg ggtaataaaa acaatcgtct
     5881 ttttcatctt tgattgcaag gccagtagtt catcctgcat ctgtacgcga atcagaggat
     5941 cgagagcaga gaaagcctca tccattaaaa gcacttcagg attattagcc agagcgcgag
     6001 ccagtccgac acgctgttgc attccaccgg aaagctcgcc taccatctga ttttcatatc
     6061 ctttcaatcc gacaagcttc atgctttcca tcgctttctt ctcacgttcc tctttcttca
     6121 ctccctgaag ttcgaggccg aacgcgatat tgctcaatac ggaacggtga ggtaacagac
     6181 cgaaattctg gaaaaccatc gccagctctt tccgacgaac ctgcaataat tctttttcgg
     6241 aaattttaga tatatctact ccgtttacaa gcacttgccc ggtagtagga cgtatcagac
     6301 gattgataca acgcagtaat gtcgattttc cacttcccga gagtcccatt atcacgaaaa
     6361 actctccttc attaattgaa agattggcat ctttcactcc taccgtacaa ccggtatctt
     6421 tcagaatttc ctctttactc ttatcttttt tcaacatctt gagggctttc tgcttctcgt
     6481 taccaaagat aaggtacaaa tcctttattt ctattttact catataatat attggtttag
     6541 attataatat ttgttttgtt ttcaactgcc gcattcctta ttctcactta cgataaacaa
     6601 gttgaatgtt cgcatggttc agtcatgtca catgataaca tgacggtccg acgtttttta
     6661 aatggttaaa aaaaaacaga cagagtagtt taaaaggaat agaatttgat aagattatcc
     6721 tcttaatgaa cagtagaaaa cagtattttc ataaataaat aacagtctgt tcttgcatat
     6781 tgttggcaca aaggtaagga aaatagatta aatatgcaaa tttcattcag gtacggagta
     6841 attccaaaga tgctttttca agtctacgca tccattttgt ttgaaagaga tcccttcttc
     6901 caacaagagt tgtttctgct ctgtccaacc cggaacaagc cgtcccgacg cattgacaac
     6961 ccgatgacaa ggcgcagata aatcatccgg aatctgtttc aaagcacgcc ccaccatacg
     7021 ggaacattga gacattccca ataatgcggc aattccccca taggtagaaa ctttacctac
     7081 cggaatttct cggacaacct gatacacctc ttgacaaaag gatgcggaaa ggctcgcctt
     7141 atctacttta taatctttca tcactcaaac attactttat ttcagttcca aaactagata
     7201 aaaagaaaag aatttgcaaa taataaaagc atttcaaata aaatatgcaa ctttatttgc
     7261 tttatttaca aataatcccg acctttgtac ccattaaaag caaccctatt attaacaaaa
     7321 caagcactgc tgttatgaaa aagaaaacta tcctgttcgc ttcttgttta ttaggagcac
     7381 tggctttcag ctcctgtgag aagaaccttt atgatgaaag taaacaaccc gagaaagaaa
     7441 agaagatgac tgacttggaa gtacctgccg atttcgactg gaaaggttct caaaatgcca
     7501 aagtgaaaat tgccagtcaa tcaactgcta ctatttctgt atttctagaa gaaaattgca
     7561 atgaagaggc tttgatgctt cgaatggatg tcgatgccaa cacatcaaaa ttggaactcc
     7621 caattgaaat tcctgcatat ataaaaaatg tgtatgtaaa atatggtaat ggctctgaaa
     7681 tacaaactgt tcctgttgaa agtaatggta ctatttctat agtagtacct gctaacgcta
     7741 cggcattatc cagagttacc acaagagcta ataaagaagt tgaaacgaac aacatcttca
     7801 attatccggg atatggcaac ggaactatta tgttcgaaga tatgtatcca gctttaggcg
     7861 attatgattt taatgatttt gttgcatggt ataatttcca aattgacggt ttttattgga
     7921 gtcacaatca atgttatgca gaatacttaa tgataggatt ccaaatcaga gctataggag
     7981 gtatatatga ctacaatcct tatatccgct tggcagaagt acaatataat gaacttgatt
     8041 tagaagaaac tcaaatgtat cttgagcgta acaatcctga agaggctgaa aatatcaaaa
     8101 tcctaaaagg cccaaaaggg gaattgatta tttcactaaa gaaaccggcc attcctaacg
     8161 gatacaagta ttataatacg gaggtaaatg aaaaaacaaa gcctaaaaaa atgatggcca
     8221 tttacttggt gttcaactca cctgttaacg ttaaaagcct acaagacagt aaaatggact
     8281 tttatattgc aaaaactaat aaaggacaag aaatccactt aaaaggttat agcccggttt
     8341 attataacag caacgaaagt tatgtaaatg aagacaactt tatatgggga ttaaaagtac
     8401 ctgcatcttt acatcatgcc agagaagaag taaacttctt ggaagcatat ccagactttg
     8461 aacaatgggt aacatcggga ggtcaagaga accaaagatg gtggaataag ccaaaaacga
     8521 ataagttgat tatgaattaa taaatataca gtaaatcata tactgaatta aataagaggt
     8581 aaggtatgtc aatagatttc cttacctctt atttttatca tatgaattcc atagaagtat
     8641 aaacagataa atgctcacca ccaaattttg cagattctat cctatccttt cctcttcaac
     8701 aaatctgtcg gactctctcc aaactgttct ctataacatt tagtaaaata agaaggagaa
     8761 ctaaaaccaa cttcataacc tatctctgcc actgtcatat ccgacgaagc aagcagggaa
     8821 gcagctttct tcaaacgagc tatacgaagc agttcattcg gggaataatt agttagggat
     8881 ttgattttgc gatagagttg cacacggctt aatcccatat ctttacccaa gtcttccaca
     8941 ttcaaatttg aatctcccat ctttgcctca atcaaagctt tgaatttttc cacaaagtct
     9001 ttatccatat cacagacatc ctctttcgcc aacgtttgtc cgtcaccaaa aaactgtttc
     9061 aggcggcggt gtgaatctat cagattacga acgcgtgcca atagtaattg cgaactgaaa
     9121 ggcttggaga tataagaatc tgcaccacca tcataccctt gaattcgttg ttcatccaaa
     9181 gaacaagctg tcaataggat aacaggaata tgacaggttt gtaattcgct tttcaagcga
     9241 cgacaacatt caattccatc catcccgggc atcattacat cggagataat caagtccggg
     9301 acatatttca tagctttacg aataccttcc gagccgtatg cagcttctat aacagtataa
     9361 tcagtgtgaa gcaatccatg cacatataag cgaatatcag cgttatcatc aataatcaga
     9421 acgcaaggtt tggaagagtc ataacttttt tccaattcct cttcttcgta agttaaagca
     9481 tcattcaagc tcgaagaacc ggaataacca gaagttgcag gagttacggg agccccagca
     9541 acggcagagg ttgcagcatc ggtggaggtt acagaagtag cagggacaga gaatgccgga
     9601 gagttttcag aaacaacagt ctcgcaagtc tgtacaggca aatcaacggt aaagatagtt
     9661 ccttgctttt catcactttc caccgtgatg gtacctttat gcaattccac aaaagccttt
     9721 accaatgcca gtccaatacc cgaaccggca tggtgcatat ctatcttata gaaacggtcg
     9781 aaaatattcc gaatatgctc cgcagaaatc attgaaccgg tattggcaac ggtaaagcga
     9841 atccagcaat gatcgtcttt agtcagggaa gacaagcgta cagttacttt tccgttttcc
     9901 ggagtaaatt tgaaagcgtt ggaaaggagg ttgaaataga tgcgttccaa cttttctaca
     9961 tctgccaatg tgcggtaatc cgtatccggc atataatcga atgagaaatg aatatgcttc
    10021 ttccgggcta ctgccatgaa agattcgttc catccttcaa aagaagaaag aatgtctaac
    10081 gaaataggag tatattccat ttttccattc tcgtatttac gaaaatccag aatctgattg
    10141 acaagacgca aaaggatatt cacgtttcgc tgaactaaca ataacattcg gcgctgatct
    10201 tcactcaaag acgaatcagc cagtaaatgc tctaccgggt cggcaactaa tgtcagtgga
    10261 gtacgaaaat cgtgagatat atttgtgaag aaaaccagct tggcatgagt cgcttcttcc
    10321 agttgatgag aaagctggat aagctgatcc cgctgttctt cgagtttgtc acgctgttct
    10381 tcaagaatat cccgttgctc ttcgagttta tcgcgctgtt gctctacttg tttcttctgt
    10441 tcggacaact ctttattcag gcgattcttg gaacggaggg atttatagac taccaacaac
    10501 aatcccgcta ctaataaaag aataaccaag ccgccataca tcacgacctg ctgcgtagct
    10561 acacgcgaca gatacccacc gatacgtccg ttcaatgttt caatcttctg atccagttcc
    10621 gagatatggg tagtctgaag ttgcataacg tgcgcgttcg tgcggtctac aacggcagta
    10681 ttcatgaccg tttcgcgagg ataagacttc ttctcaagaa tattcatggc cagttgcatc
    10741 actttgtccc cattagtcgg ataaataaaa gttgcatcca gcacattgtc aagcaccaat
    10801 tcaagcccgt ttcctttgcc gggcagggca tcaatgccaa caaaaatcat ttccttttca
    10861 cgtccggctt tcttcgcagc ttgataggct cccggagcga tacggtcgtt atgtgcatat
    10921 accgcatcaa tcttcggatg acggcgaagc atactatcca tttccacttc tgccggttca
    10981 cgttcccagg cagcatccgc tttatcaatc agtttgatat ccggataatt gctgatagca
    11041 gccataaatc cctgatggcg ttccatggca ggggtggaac cacccagtcc ggtaagctcc
    11101 actacattcc ctttcccttt cagacttgat gcgatataat ttcctaccgc acgacctatt
    11161 tcataattat cggcaccgat ataggcagta tatttatcag aaagtatctt ccggtctaca
    11221 agaatgacag gtattccttt ctgataggcc tcctccacaa ttggagtcat gggagccgct
    11281 tcattggcgg aaattatcag taaatcaact cctttatcta taaaataatg aacatcttcc
    11341 gcctgcttac ggttatcatc cgccgccgag cggatttcaa ccgacactcc atcataaaac
    11401 atcgcttcgc gaagaatctc atcattcatc ttgtgcctcc aagagtcatc gctacattgg
    11461 gccaccccaa tacggaaacg aggcgcatcc tgccgacagg ccgccaagcc caaaagacaa
    11521 aacaagactg ttatccactt cgtatatttc atcgcttcaa tcattccctt tctttcgtat
    11581 atcttttgta tttctttctg taatccaaat ttctctcccc gcattatttg cattcaccac
    11641 cgggaaatac atcagttcca ctttcacagg gttcagcgta tattttccag taaagcgtgg
    11701 aagcaaagga accgtaaact gataagtacc taccggtaat ttttcgctaa agataacagt
    11761 tttctcttta aaatactcac gatatacttc agaacgggag aaattaacag gttttgaggc
    11821 ataactacaa cctgccggaa caggaacttc gagcatcaca tattgcgcac cctcctgctt
    11881 cacctgcaag gtaactgtca atgtaacagg tacacctgcc accaaagagt ctttttccaa
    11941 agtcgcctcc accttgaaag catcactctg acgagcattc atcacacgct tcattgaata
    12001 gacactatac aataaaggct cttttcccgt ttttgaaata agcagactgt cgcctgctgt
    12061 cagccgggca tgataaggaa attccgtaat tcgttgatga tccttaccgc tcacagacac
    12121 cgacgttcct gacatccctc cggaacctgc cagcaaatcg gtcagaacag ttgccacagc
    12181 cgaagaagcc tgatacgtat tccatccgcg ctccttagtc cgcaaaatat acaattgcat
    12241 attttctttc aacttacaca gggaagggtc atttttaata atccggtagg ctatcaatgt
    12301 atttatcatc tgatttccct cccaataata agtacgccgt ccgtcgtcac agtaaacacc
    12361 ttccagcata tcctttttca gataaggacg tacgctatca cccacattca ccgaatccac
    12421 ctgttgcttg atttcccaga gaagcagctt ctctttcaag tatgaaagag gacgataata
    12481 cttgtttcta tttgccaacg agtcttcttt ctgttccaat tgccggacga aaggttccaa
    12541 taatctgact gccgaagaat aatccgcctc tactttccac tcatgcagag catgaagtat
    12601 ttctatatct tccagtttca ttcctcgata aggacgcgta tgagcatact ccactttcaa
    12661 accattcaga ttcaactcca caggataacc tgcatcttgc gccatcttca aagcccgcag
    12721 aatatgcgca gacatccaga aagaagtatt ttcagagttc ccccaccacg accataactg
    12781 atgtttgttc tgatgattcg tcagtcgatg gatgataggt cgaattgctt tatctacttt
    12841 caccttttca cccttactct gcatatactg ttggtaagcc aacaaaccga ttaacttgga
    12901 tgccagctgc tcattgcaca aatatttgta tcctgtcaag taattcactg attctttata
    12961 gatgtccaac tgattgtcag tgatactcac catcacttct tcatcctcgc cggattgcac
    13021 tttgaccgtc tttgcatcgg acagaatacc caatgtgccc tccgccaatt cagttccctg
    13081 tggcagtatc ggaatcgtat attcctctcc atcctgatag ccatcgtcgc gagtgaaaag
    13141 atagctgatg gtcacgctat cggcatgaac tgcctgcatc ggcactgttt catgaaatcc
    13201 ctccatgaaa ctcacttcct gccgtttcaa cgtatccgtt ccgacgcaga actgtgtctt
    13261 tccggctatg tgctgcccat ccagataatt gcggatagtc ccgaccaccg tactctgatc
    13321 cccctccacc aagaagcggg gagttttcaa ctccgccatc aacggtttgt aagagcggac
    13381 gaaacgtcgg aaagtacccg tctgcaaacg acggttcatg ccataaacga cagtttc
//
