LOCUS       c00045_gnlPro..        15578 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GACJGOEM_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:56:10
            Original ID  :: gnl|Prokka|GACJGOEM_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15578
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15578
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2605:5578]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2606..5578
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15578
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15578
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..436)
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MYRKVTTLISFAAFILFWIIMCPLGMYGQESKWVDMNPVRKRYLR
                     FHKDFAVDSVKYPIWEYQNSVIFANSGVTLQFKKGGPFFYTDQSPLHKGEYNVSGVIAP
                     LWNGHVYGMGRQMNLIGIGVFNYAAIGYNKSLSDNLFADVA"
     CDS             complement(1018..1857)
                     /locus_tag="ctg45_2"
                     /transl_table=11
                     /translation="MKRIFILLFVSLALFSCEKEENNKILEYQVLPSENVSKPFNCLGE
                     KRTITFTIIQKTLIDDVLDSEVPIIPKDVSIEFDKTLFSDIETKVKGDQVVLNITSNIN
                     KEDKILNGDLQISYSTINGIKVEKIPLIIDKGELTFMYKIHSEQNPFILPAEGGKFELP
                     FTCKKQTYLNGQFIEERYSALKGLRFKTISTGNIWFLTVRKDGEKIGFYKFTFVGEGPY
                     NQKREPECYFNIYIHDADVVADNPPEIFRQDFMQPQTPGEDYYIPSRASYKHGTFDF"
     CDS             2606..4834
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="Gly_radical (E-value: 2.3e-46, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIKAKQEDLHNLTGPMTDARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4850..5578
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_4"
                     /sec_met_domain="Radical_SAM (E-value: 2e-29, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(5606..6049)
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDEDGKAADTRTSRQKESLHRLVRELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(6036..6227)
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="MITLILDQMKEIVTKILDVIMFLVPFFGKRKRNRIVREVRFNATH
                     KEVCNVKTTEREKDDEKD"
     CDS             complement(6224..6727)
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             6921..7151
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MYYPDQPFHIRTYKKSELAHLYNPNVCLKVALQILRRWIVYNPPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             7239..9356
                     /locus_tag="ctg45_9"
                     /transl_table=11
                     /translation="MDHFTIFQDFYRVIAEMTEEEIVSAISNGTYRETVEDVRRIFAEQ
                     GEKAANEKKIELPEITFSANYRGGRSNATLVKYLGYIVVDIDHQTQEALARILALAKKC
                     AHTRIAFISPKGMGLKIVVRVCRTDGTLPETIQEIEDFHHAAYHKIASFYAQLCGVEVD
                     TSGQDVSRTCLFSYDPDIYFNPDATAVIVEQPPMFFKSQKKKRASGKKKKTTAPDNNPL
                     TEQVALNYHSSHTSLMVTLNYYHNKSEKYVTGNRNNYLHCLACMYNRYGVPQEEAAAFI
                     KSQFTDLPADEMDALIGSAYGHNEEFDTRKLNSTQKRMLQIEQHIKENYDTRYNEVLHI
                     MEYRRRKTDTEQPEPFHILDEMMENSIWMEMNELGYSCTVKTIQNLIYSDFSITYHPIR
                     EYLDSLPEWDGTDYIGILANSVHTSHQKFWVECLERYLVGMCAAATQDDVVNHTVLLLC
                     SEIQNIGKTTFINNLLPPELRAYLSTGLINPSNKDDLAKIAQAMLINLDEFEGMSGREL
                     NIFKDLVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVDSME
                     FIKINYAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPE
                     RFEKVHYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIID
                     TEQVKSNRLYE"
     CDS             complement(9605..9910)
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTVTRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCRIEFSMSL"
     CDS             complement(9891..10223)
                     /locus_tag="ctg45_11"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFDRLDTGTQDKILYVLMLLQTQDRIPLKFM
                     KLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIEKAKILRKEY
                     YGSKNK"
     CDS             complement(10280..10525)
                     /locus_tag="ctg45_12"
                     /transl_table=11
                     /translation="MSHLTPVTIEYRGNPKQYVSVVLDAINRGRLTYDGIANCEQTFRA
                     LASVVDVISPKNGKTLSVETLVSYEKKKRAGEFEEK"
     CDS             complement(10534..10668)
                     /locus_tag="ctg45_13"
                     /transl_table=11
                     /translation="MENSCNDELFCSLKNELREVTAQINVHSEKLMELLDQKKESSVN"
     CDS             complement(10788..12059)
                     /locus_tag="ctg45_14"
                     /transl_table=11
                     /translation="MKRFILLTILCCLVLSISAQIARDEIFEDIHRSAANHYAYPDPHF
                     TMTAPPKGYKPFYLSHYARHGSRYRVNPDDYTKPLAILREAEKDGVLTDLGKKALWLVD
                     SLARGAENRYGDLTPLGARQHRGIARRMYNNFPEVFQGAAEVDARSTTVIRCILSMTAE
                     CLQLQSLNPELRIKDEATSYDMYYMNYGNEYFKKKRQEDEVIAVKAAFRKEHLHPERLM
                     KSLFNNDNYVKWKVDAGKLMSYLFELAAITQSHDTDLDLYSLFTKEECYDLWLISNLNW
                     YIDYGPSPLTQGKMPYVEANLLENILNTADTCVVKKENSATLRFGHETCLLPLACLLEL
                     GDCAYQTTDINKLSDIWRNYRIFPKACNIQFVFYRKKGNDNILVKILLNEQEMKLPLAS
                     ELVPYYHWEEVERYYRNKLATFVH"
     CDS             complement(12096..13301)
                     /locus_tag="ctg45_15"
                     /transl_table=11
                     /translation="MTIPPFPKWEKGYLDIHHINTGRGNCAFLIFPDGTTMMIDAGDFD
                     GKEYAAKYAPMHAAPIFPDSSYTPGSSIINYVTNLLGKDVVIDYFLLTHFHSDHYGDVQ
                     KATGTSKNGYRITGLTEVGDVIPIKMYVDRDYPDYQFPVDLRSKNDGVDLPTFLNLLEF
                     LNYQEKHNGLKVEKFDIGSNTQFVLKKEPKSYPGFEVRNIKSNNRLWTGEGKKTTILFT
                     KEELMAKNGKYSENQMSTAIVVKYGAFKYYAGGDNSGLVDQDHAEWYDIETPMAPIIGK
                     VSAVSLNHHSNRDATNRNFLEVLDPKVVVAQSWSTDHPGAEVGQRLLSKNIGTQPRDVF
                     MTYYDDETGVAIGPWFARSLKAKQGHIVIRVYPDGEYEVYVLDARKTDLVISNRFGPYS
                     SE"
     CDS             complement(13404..14255)
                     /locus_tag="ctg45_16"
                     /transl_table=11
                     /translation="MKYLNILLIILPFIFSCSSDTPENDKEKIPPIIDTSIRVGTFNVD
                     VGQTATAEEIALSLKSFYLDILSLEECPILIDKNSGVEEFYSIIGKALGMEYFYIGDIS
                     SGNHWIEWGKDKTGKYAGKYKVILSKTPILQSKEFALEGKGWTHSSTIRIETKIKNKEL
                     TFYSLHIPGSAGVVEGSVMKNLVDVVLMKDTSKRIIVMGDFNDLPETNAMQYIFNSGFK
                     SVWDDVEDAEQYIDKYKYGQIDNILINKNSGMKAEIAYSIFKKDISLSDHPFLWSKIII
                     GE"
     CDS             complement(14265..15188)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fn3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_17"
                     /sec_met_domain="fn3 (E-value: 4e-11, bitscore: 35.0,
                     seeds: 98, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDILNFIIILSMSLLLASCGDDKDGINQPDPITGLTTEVFEESI
                     SLSWDVPNGEVKKYVIVYNPGDGLIDIVDPAITKYSIEKLKPGTDYEIDLYWVNNANVR
                     SLASTVNVTIPQKEGVIEHIYVGDLLLPNQKAIDNLQLKYTSVTGKLRIGNGTSGSDIT
                     DVSMLANITEVGTNLEVDGNSLLGNLDFLKNLKKIGGNFWLRNNPMLTSITGLKNLSEI
                     KTNLYIMGNPSLTNLNGLEGLTAVKLINIGIRSGNKSDKGNEKLTDLSALKPILTSLPT
                     VSYHCEGNAYNPSVDDILNDRGSDSK"
ORIGIN
        1 atgcaacatc agcaaataaa ttatctgaca atgatttgtt atatccaata gcagcatagt
       61 taaaaacacc aataccaatt aaattcattt ggcgtcccat gccgtaaacg tgaccattcc
      121 acaatggggc tattaccccc gacacattat attccccttt atgtaaagga ctttggtctg
      181 tgtaaaaaaa cggcccaccc ttcttgaatt gaagagtaac accagaattt gcaaaaataa
      241 cagaattttg atattcccaa ataggatatt taaccgaatc aactgcaaaa tctttgtgaa
      301 aacgcaaata ccgttttctc acaggattca tatcaaccca cttcgattct tgaccataca
      361 tcccaagagg acacatgatg atccaaaaca aaataaatgc tgcaaaacta attaatgtag
      421 tcacctttct atacatattg attttcatca ttatgcccaa agcatgaaaa taaaagcatc
      481 atacacaagg gctgtaaata aatccactgt caatttacat ttctgcgata tttatttaaa
      541 tgaacaatca ggatttttgc acgatttttt acataatcct ttaacagata atataaacag
      601 aaaaactatt acgaagcatt ttgtataata ttcctgttcg aataaatcaa caagcagtgg
      661 gattataatg aatgttgata gacaaaagat cattatcaga gtgctttttt tcatgtttta
      721 gcaaaaagta gcaactccta ctaaggcgcc gctctaccca cctaaagcgg ttcccgatac
      781 tgtaccgata acaggtagtg tgacagtacc aactcccgca ccaccaagcg caccctttcc
      841 agattatcca ttgaaatatt tatcacttct tgaaggtatc tctcaaaaag aacatgatta
      901 gagcctccta tttcttcaac tgtatcatcg gaacataaaa ttaaaaacat aattggcaaa
      961 atcaacaaca tacatactgt ttcataatta atataattaa ggttaatact gaatatgtta
     1021 gaaatcgaaa gtcccatgct tataagaggc ccgggaaggg atataataat cctcacctgg
     1081 ggtttggggc tgcataaaat cttgtctgaa tatttctgga ggattatctg ctaccacatc
     1141 tgcatcatgg atatatatgt taaaatagca ttcgggttct ctcttttggt tatatggccc
     1201 ttctcccaca aaagtaaatt tgtagaaacc gattttttcc ccgtcttttc tgaccgtaag
     1261 aaaccagata ttaccagtac ttatcgtttt aaatcttaat cctttcaatg cagaatacct
     1321 ttcctctata aactgcccat tcaaatatgt ctgtttttta cacgtaaaag gcaactcaaa
     1381 cttgccacct tcagctggta gaataaaggg attttgttcc gaatggattt tatacataaa
     1441 tgtcaactcc cctttatcta taatcagtgg aattttttct acttttatgc cattaatagt
     1501 agaataagaa atctgtaaat caccattcaa aattttatct tccttattaa tatttgaggt
     1561 tatatttaat acaacttgat caccctttac ttttgtctct atatcagaaa aaagagtttt
     1621 atcaaattct atcgaaacat ccttgggaat aatcggaacc tctgaatcta aaacatcatc
     1681 tatcaatgtt ttttgaataa ttgtaaaagt aatagtacgt ttctccccca gacaattaaa
     1741 tggtttagat acgttctcac ttggtaacac ctgatattca agaattttat tattttcttc
     1801 tttttcacag gaaaataatg ctaaggaaac gaatagaaga atgaatattc ttttcatatt
     1861 aatacagttt agtttttttg caaattaaaa gatttttccc gtacaataaa ataccaatta
     1921 attggtattt tattacaaat aaccattcaa tttcattatt atgcccaaag catgaaaata
     1981 aaagtataac atacaagagc tgtaaacaaa gacagaatta ttcgggagac tccctactct
     2041 aaaaaagtta aaaaaaagaa aatgatttaa ataaatatta gtataacaat gtcatcaaca
     2101 acacaatatc cccttttcaa attatacaat aaataatagt taagcaacca aagacagcgc
     2161 aaagccaaac aagtaataaa agaataaagt attaaataaa gcaaaaacac ccaattctac
     2221 tttttagggt gtaaaattgg gcgttattct tgtaaattgc tgattatcag cgtttattgc
     2281 ggagagacag ggattcgaac cccgggtacc tcgcagtaca acggttttca agaccgccgc
     2341 aatcgaccac tctgccacct ctccaaaact tctttatcag aagtgctttt cgttaaaagc
     2401 ggtgcaaagg tacgaatata ttttaaactt acaagagttt tcacaaaaaa aaatcacgaa
     2461 catcatttcc aaagaatagc aatatctagg tattttatgt tgaaaagcat aaaatagagc
     2521 atatttatgc tgattatatg aaaaaacgtt gtaactttgt gcgctctaaa gaaaaggata
     2581 actacaacct ctaattttat catttatgga attaaataag atctttaaag acggtctttg
     2641 gagcactgaa atcaatgtca gagatttcgt aagtcataac atcactccgt attacggaga
     2701 tgcttctttc ctcgaaggac ctaccgaacg cacaaaagct gtatggaacc gctgcctcga
     2761 agcactggca gaagaaagag ccaataacgg agtacgctca ctggataatg tcaccgtctc
     2821 aaccatcact tctcataaag ccggatatat cgacaaagaa aacgaactga tcgtcggtct
     2881 gcagacagac gaacttctga aacgtgccat caagcctttc ggaggtatca atgtggtaag
     2941 caaagcctgc cacgaaaacg gcgtggaagt ggacgaccgc gtaaaagata tattcactca
     3001 ctaccgcaag acgcacaacg acggagtatt tgacgtatat accgaagaaa tccgttcgtt
     3061 ccgttctctg ggattcctca ccggacttcc tgacaactat gcccgcggac gtatcatcgg
     3121 cgactaccgc cgtatggctc tctatggtat cgaccgactc attaaagcaa aacaggaaga
     3181 cctgcataac ctgactggtc cgatgactga tgcccgcatc cgcctgcgcg aagaagtggc
     3241 agagcaaatc aaggcattga aggacatgaa ggtaatgggc gaatactacg gactcgactt
     3301 gagccgtcct gcctacaccg cacaagaagc agtacaatgg gtatacatgg cttaccttgc
     3361 tgccgtaaaa gaacaagacg gtgctgccat gtcactgggt aacgtctctt cgttcctcga
     3421 catttatatg gaatatgaat tgagcaaagg aaccatcaca gaatctttcg cacaggagct
     3481 gatcgaccaa tttgtcatca aactgcgtat ggtgcgccac ctgcgtatgc aatcttacaa
     3541 cgacatcttt gccggcgacc cgacatgggt aaccgaatcc ctgggcggac gcctcaacga
     3601 cggacgcacg aaggtgacaa agacttcttt ccgcttcctg caaacactct acaacctcgg
     3661 cccttcaccg gaaccgaacc tgactgtatt gtggagcccg gaacttccgg aaggattcaa
     3721 agaattctgc gcaaaagtat ctatcgacac ttcttccatc caatatgaaa acgacgacct
     3781 gatgcgtgaa gtacgccagt ctgacgacta cggaatcgca tgctgcgtat cttatcagga
     3841 aatcggaaaa caaatccaat tcttcggcgc acgttgcaac ctggcaaaag ccctgctgct
     3901 tgccatcaac ggcggacgtt gcgaaaacac cggtacggta atggtgaaaa atatccccgt
     3961 actaaccagc gacacactga acttcgaaga agtaatgagc aactacaaga aggtattgac
     4021 agaaatcgcc cgtgtttaca acgaagcgat gaacatcatc cattatatgc atgataagta
     4081 ttactacgaa aaagcccaaa tggctcttgt agataccaac ccacgcatca accttgctta
     4141 tggtgtagcc ggactttcta tcgccctcga ttcactgtcg gccatcaaat atgccaaagt
     4201 aactgcacgc cgcaacgaca tcggtctgac agaaggtttc gatattcaag gcgaattccc
     4261 ttgcttcggt aatgacaacg acaaggtaga ccacctgggt gttgacctgg tctatttctt
     4321 cagcgaagaa ttgaagaaac ttccggttta caaaaatgcc cgtcctactt tatctttgct
     4381 caccatcact tccaacgtga tgtatggcaa gaagacaggt gctactcccg acggacgcgc
     4441 caaaggtgtc gcttttgctc cgggagccaa ccctatgcac ggacgtgaca agaacggtgc
     4501 catcgcctct ttgagttccg tagcgaaatt acgttaccgc gactcacagg acggtatcag
     4561 caacactttc tccatcgtcc ccaaatcact gggagctact gaagaggatc gcgtagaaaa
     4621 tctggtgaca atgatggatg gctatttcac caaaggcgct caccacctga acgtgaacgt
     4681 actgaaccgt gaaatgcttt acgatgccat ggaacatccg gaaaaatatc cgcaactcac
     4741 catccgtgtt tccggttatg ccgtaaactt cgtgaagttg agccgcgaac atcaattgga
     4801 agttatcagc cgtagcttcc acgaacgtat gtaatcagat ctactcaata tgacgataaa
     4861 cgtacattca tacgaaagta tgggaacatt cgacgggccg ggcttacggc tcgtcgtttt
     4921 tcttcaagga tgcaatttcc gctgcctgta ttgcgccaac cctgacacaa tagccgggaa
     4981 aggaggcaca cctactccac cggaagaaat cgtccgcatg gctatgagcc aacgtccttt
     5041 tttcgggaaa cgcggaggag tcactttctc cggaggagaa cctacgtttc aggccaaagc
     5101 actagtccct ttagtgcgtg aactgaaaga aaagggaata catgtatgca tagacagcaa
     5161 cggcggtatc tggaacgaag aagttgaaga acttttcaaa ctgacggatc ttgtattgct
     5221 ggatattaaa gagttcaatc cggcacgcca tcaagcactg accggaagaa gtaacgagca
     5281 aaccatccgc acggcagcat ggctggaaga aaacgagaaa cctttctggc tgcgttatgt
     5341 attagtgccc ggatacagcg atttcgagga agacatccgc cgtttaggag aagctctggg
     5401 aaaatataag atggtgcaac gagtggaaat cctgccttat catacattag gcgtacataa
     5461 gtatgaagcg atggagcagg aatacaagct gaaagacgta aaagaaaata cccccgaaca
     5521 acttgaaaaa gctgcggagg tatttaaaga gtatttcact actgtggtgg tcaattaacc
     5581 accacagtaa taaataggat aaaaatcacc atgtctctgc tttcacctcg aaacagggac
     5641 actctttgat ccgctcccaa gggtcaacaa ttccattata attggtgtca ggactcaaat
     5701 cacggtgtcc caccactttt gcatccggat aacgctgcaa cagttcgcgc accaggcgat
     5761 gcaaagattc tttctggcgg gaagtacgcg tatccgctgc ctttccgtcc tcatccagtc
     5821 cgccttcata acacacccct aaactaatcg cattaaaacc gcgtgcatga gcacccaccg
     5881 tatcttcatc cctcatcggc tctatctgtc ccgacttgcg aatgtagtaa tgataccccc
     5941 aacacgaaaa gccccgaaag cgatgggcag tgtccacatc cttcgccgtg aagtcgcgat
     6001 cagcacgggt agcagagcag tgaatcacaa tcagactaat ctttctcatc gtccttctcc
     6061 ctttccgtcg ttttcacatt acacacttcc ttatgggtag cattgaagcg cacctctctc
     6121 acaattctgt tccgctttct ttttccgaag aaaggcacaa ggaacataat tacatccaaa
     6181 atcttagtta caatttcttt catttgatcc aatattaaag ttatcatgct gccggatccg
     6241 gagcttctcc gcttccacca ccgtctgaac caccaccgga acctttgtca tcgtcttctc
     6301 cttcattgcc gctaccgccc gtttgagcca ccgcacgcgt cgttacctgc tggtagctaa
     6361 gaatcttcgt gatgtccgcc aacgtctttc cgggacggaa aataatatgg gcagccgtaa
     6421 tcagcgaact tgaaaactcc ttgaccgaca cagctccttc actgttcaac ccgatctgca
     6481 aactgcccaa atcacccagc cggactattc ttcccgcttt caacgcacgc ttcgcctcat
     6541 aaagaatacc cgaaatggcg gcacgcacat ctgtctccgt acaggtagac cgactggtga
     6601 ttccttcgca caactcttca aaatccaact ctcccgaagc ctgtgcctgc gcgtaatact
     6661 ttgccgactc atcctttttg gcaggattct tgcgcggcac tactgaataa gttactgtca
     6721 ttgccataat aaaataattt taagatttca cacatttcga acgcgttcct tatttgttaa
     6781 cgacataaag ataacacatt ttccatcctc cggattcccc aacgaagttt cctgatactc
     6841 tatgaataat aatgacgtta ttcttttaat aaaccattaa ttttcagtaa ctttatagca
     6901 taaaccaaac attattcatc atgtattatc cggaccagcc gtttcatatc cgcacttata
     6961 aaaagtcgga actagctcat ctttacaacc ccaacgtatg ccttaaagta gccttacaaa
     7021 tactacgtcg ttggattgtc tacaaccctc cgctcctgca agaactcgaa caagaaggct
     7081 atcgtgcccg caaccgcctt ctctctcccc ggcaagtggc aacgatcata cgctatttgg
     7141 gagaacccta ggaacttaat caaaaaaacg aaaagttcca ttctattatt ttacaaacaa
     7201 atttctttgc aaccgcaaat taaaaagaac aaaccaacat ggatcatttt accatctttc
     7261 aagactttta ccgcgttata gccgaaatga cagaagaaga aatcgtatcg gccatcagca
     7321 acggcacata ccgggaaacg gtggaggacg tgcgccgaat cttcgcggaa caaggcgaga
     7381 aagcagccaa cgaaaagaaa atagaactac cagaaatcac cttttcagcc aactaccggg
     7441 gaggacgttc aaacgcaact ctcgtcaagt atctgggata catcgtggta gacatcgacc
     7501 atcagacaca ggaagcattg gcacgcatcc tcgcactggc aaaaaagtgt gcccacaccc
     7561 gcatcgcttt catcagcccc aaaggaatgg gactgaaaat cgtggtacgt gtatgccgga
     7621 cagacgggac attgcccgaa acaattcagg aaattgaaga tttccatcat gctgcttatc
     7681 acaaaatcgc ttccttttat gcccagctct gcggagttga ggtcgacact tccgggcagg
     7741 atgttagccg cacttgcctg ttctcttacg atccggatat ttatttcaat cccgatgcca
     7801 cagctgtcat cgtggaacag ccaccgatgt tcttcaagtc tcaaaagaag aaaagggcat
     7861 ccggcaaaaa gaaaaagacg acagcaccag acaacaatcc cctcaccgaa caagtggccc
     7921 tcaactacca ttcctcgcac acttccttaa tggtgactct gaactattat cacaataaat
     7981 ccgaaaagta cgtcaccggc aaccggaaca actacctgca ttgcctggct tgtatgtaca
     8041 atcgctacgg cgtcccccag gaagaggcgg cagcttttat caagagccag ttcaccgatc
     8101 ttcccgcgga tgaaatggac gcactgatcg ggagtgctta cggacacaac gaggaattcg
     8161 acacccgcaa gctgaatagt acgcagaagc gaatgttaca gattgagcaa catatcaaag
     8221 aaaattacga tacacgctac aacgaagtgc ttcatatcat ggaatatcgc agaaggaaaa
     8281 cggacacgga gcaaccggaa cctttccata ttctcgacga aatgatggaa aacagcattt
     8341 ggatggagat gaacgaactg ggctattcgt gcaccgtcaa gacgattcag aatctgatct
     8401 actccgactt cagcatcacc taccatccta ttcgcgagta tttagactcg ctgcctgaat
     8461 gggacggaac ggattatatc ggtatccttg ccaacagcgt gcatactagt caccagaaat
     8521 tttgggtaga atgtctggaa cgttatctgg tgggaatgtg cgctgccgcc acacaagatg
     8581 atgtggtgaa ccacactgtt ttgttgcttt gcagcgaaat acagaacatc ggaaagacta
     8641 cgtttatcaa caacctgctg ccgcccgaat tgcgcgccta tctttctacc ggtcttatca
     8701 acccgagcaa caaagatgat ctggctaaaa tagcgcaggc gatgcttatc aatctggatg
     8761 agtttgaagg gatgagcgga cgggaactga atatcttcaa ggatttagtc acccgcaaag
     8821 taatcagcat ccgcctgcca tacgcgcggc gttcgcagaa ctttcctcat acggcttctt
     8881 ttgccggcac atgcaattac caggaagtgc ttcacgacac cacaggtaac cgccgttttc
     8941 tctgctttca tgtcgactcg atggagttta tcaaaataaa ctacgcgcag ttgtatgcac
     9001 aaatcaagta tctactcaac aagccggggt atcagtattg gttcacccag tcggaaaact
     9061 cacggattga agagaacaac gaggatttca ttttccactc accggaagaa gaactggtgt
     9121 tgacacatat ccgcaaaccg gaacgtttcg aaaaggtgca ttatctgacg gtcactgaaa
     9181 ttgcggaatt gattcgcgaa cggacggggt atcaatattc tcacggaacc aaagcccaac
     9241 taggaaaagt gatgtccaaa cacggcttcg aatttcataa gggaaaaaac gggagaagat
     9301 acactgtatt cattattgat acggaacagg tgaaatcaaa caggctatat gaataagatt
     9361 tcatctcctt cgcacgcaaa aaggtgaggg ttggtgaggg tacttttgca acttttcatt
     9421 tttatatttc ttatttctat tcttctattt tcttctaaaa aaaaatacga atgttagaaa
     9481 tttaccctca cctaccctca cctttttcct ttttcttcct ctttcttcct caaaaaaacg
     9541 gtgggaaatt tgaaaaagac agttaacttt ttcaaatttc ccaccatgtt tttttaatcg
     9601 cttcttataa agacatcgaa aattcgatcc tacaacctaa cgcattcatg atgcgataga
     9661 aggtagaaac cttaggctct gtctgaccac tttccactct tgaaatataa gaacggtcgg
     9721 aaccgatacg tcgggctaac tctgcttgag taatcttagc ctttttcctt gcgtcttcga
     9781 taatttgccc ggtgtagaaa gcatacgctt tttcttctgc ttccgcacga gtaacagttc
     9841 cttccttacc aaaacgctca tctattaatg cgctgacgtt aaagaattcc tcatttgttt
     9901 ttgcttccat aatactcctt tcttaatatc tttgcttttt caatttcttt ctttggggtc
     9961 ttttctgttt tcttttggaa tccgttaaag agtatcacaa tacgtccttc atcgaaacaa
    10021 aagaatattc tatatatatt actctggtac tcaatacgaa gttcataaag tccttcttct
    10081 atcaacttca taaacttcaa aggtattctg tcctgcgttt gcaatagcat taacacatat
    10141 aatatcttat cttgggtgcc agtatccaga cgatcaaaga actctttgaa atatccttta
    10201 tatgctatta tttctctttt catactgcaa atatatgaat tgttgttcaa ctatacaaca
    10261 ttcgtctttt tattttatat tatttttcct caaattctcc ggcacgcttt ttcttctcat
    10321 aagacaccag cgtctctaca ctaagcgttt tcccattctt agggcttatc acatctacaa
    10381 cgcttgctaa cgcacgaaaa gtctgttcgc aatttgctat tccgtcatac gtcaacctac
    10441 cccgattgat ggcatcgagc acaacagaga catattgctt cggatttccc cgatactcaa
    10501 tggtgacagg cgtgagatgc gacatctctc gagtcagttg actgacgatt cttttttttg
    10561 gtcgagcagc tccattaatt tttcactatg cacattgatt tgtgcggtta cttcacgaag
    10621 ttcatttttc aatgaacaaa acaattcatc attacatgaa ttttccataa aacttttcat
    10681 ttaattgatt ataaaaaagc cattccggaa agataagcaa tcattactta cttcccggaa
    10741 tggtgactaa catttttaag accagttttt gtatattact gtttctttca atggacaaaa
    10801 gtagccaatt tattcctata atatctttcc acctcttccc aatgataata gggtactagc
    10861 tcacttgcaa gcggaagttt catttcttgt tcattgagta aaattttcac caagatatta
    10921 tcatttcctt tcttacggta aaaaacgaac tgaatattac aagcttttgg aaagatacga
    10981 tagttacgcc atatatctga caatttattt atatcagtag tctgatatgc acaatcacct
    11041 aattccaata aacaagccaa aggaagtaga caagtctcgt gcccgaagcg cagggtagca
    11101 ctattctctt ttttcacgac gcaagtatct gcagtattca gtatattctc aagcaggttt
    11161 gcttccacat aaggcatctt accttgagtg agcggagacg gcccgtagtc aatataccaa
    11221 ttcagattgc tgattagcca taaatcataa cactcttctt tggtaaaaag agaataaaga
    11281 tcaaggtccg tgtcgtgact ttgcgtaatg gctgccagtt caaacaaata actcatcaac
    11341 ttgccagcat ccactttcca ctttacataa ttatcgttat taaaaagaga cttcatcaaa
    11401 cgttcgggat ggagatgctc tttccgaaaa gctgccttta cagcaatcac ttcatcttcc
    11461 tgacgcttct ttttgaagta ttcatttcca taattcatat aatacatatc ataagaagta
    11521 gcctcatcct tgattctcaa ctccggattc agagattgca attgcaagca ctcagccgtc
    11581 atagagagta tacagcggat aacggttgta gaacgtgcat ccacctctgc cgctccctga
    11641 aacacttcag gaaagttatt gtacattctt cgggcaattc ccctgtgttg acgggcacct
    11701 aatggagtca aatcaccata tctattttct gctccgcgcg caaggctgtc tacaagccag
    11761 agggccttct tgcctaaatc tgtaagtact ccgtctttct ctgcttcgcg aagaattgcc
    11821 aacggcttcg tataatcatc aggattcact ctataacggg aaccgtgacg agcataatgg
    11881 cttaggtaga acggtttata ccccttgggt ggggcagtca ttgtgaaatg gggatcagga
    11941 taggcataat ggttggctgc cgagcgatgt atgtcttcaa atatttcatc tcttgctatc
    12001 tgtgcactta tactaagcac aaggcaacaa aggattgtca acaaaataaa acgtttcata
    12061 ctttcttttt ttaataagtt taagatacca cagaattatt cactagagta aggaccaaac
    12121 ctgttcgata taaccaagtc tgttttccgg gcatccagca catatacttc atattccccg
    12181 tctggatata ctcttatcac aatgtgcccc tgttttgctt tcaagctacg ggcaaaccaa
    12241 ggaccaatag ctacccccgt ttcatcatca tagtaagtca taaaaacatc cctaggctgc
    12301 gttccgatat tctttgataa caaccgttgc cccacttccg ctcccggatg atcggtactc
    12361 catgattgag ccactactac tttaggatcg agcacttcga gaaagttccg gttagtggca
    12421 tcccgattgc tatgatgatt gagcgacact gccgacacct ttcctattat gggtgccata
    12481 ggagtttcta tatcatacca ttccgcatgg tcttggtcta ccaaaccaga attatcccct
    12541 cccgcataat acttgaatgc gccatatttc accacaatag ccgtcgacat ttggttttca
    12601 ctatacttgc cattttttgc catcaattct tccttggtaa acagaatagt cgttttttta
    12661 ccttcccctg tccacaaccg attattcgat tttatattcc tgacttcaaa ccccggataa
    12721 gatttcggtt ctttctttaa tacaaattgc gtattagagc ctatgtcgaa cttttcgact
    12781 ttcaatccgt tgtgtttttc ctgatagttg aggaactcca ataggttcaa gaaagtaggc
    12841 aaatctactc catcattctt tgatcgtaaa tccacgggga attggtagtc aggataatcc
    12901 ctatcaacat acattttgat aggaatcaca tctccgactt ccgtcagccc cgtaatacga
    12961 tatccgtttt tggaagttcc agtggccttc tgaacatcac cataatgatc ggaatgaaaa
    13021 tgggtcagaa gaaaatagtc aatcactaca tcctttccca atagatttgt cacataatta
    13081 atgatagacg aaccgggcgt ataactacta tccggaaata tcggagctgc atgcatcggt
    13141 gcatacttag cggcatattc cttgccatca aaatcaccgg catcaatcat catggtcgtt
    13201 ccgtcaggaa aaatcagaaa agcgcaattc ccccgcccgg tattgatgtg atgaatatca
    13261 aggtatcctt tctcccattt agggaaaggc ggtattgtca tttgagcctt gattatacaa
    13321 ctaaaaacga gtaaaaatat gaaattaact attttcttta tatccatcgt tctatcaatc
    13381 tgtttataaa ttactactgt actttattct ccaataatta ttttactcca tagaaatgga
    13441 tgatctgaaa gactaatgtc ttttttaaaa atgctatatg cgatttccgc tttcatacca
    13501 gaattcttat tgattaatat attatcaatc tgcccatatt tgtatttatc aatatattgt
    13561 tcagcatctt ccacatcatc ccatacactc ttaaagcctg aattaaagat gtattgcatg
    13621 gcattagttt ccggcaaatc attgaagtcg cccatgacta tgattctttt actagtatct
    13681 ttcatcaaaa caacatctac taaattcttc atgacagaac cttcaactac tcctgcgcta
    13741 cccggaatat gcagactata aaaggttagt tccttatttt taatcttggt ttcaatccga
    13801 atagtcgatg aatgtgtcca accttttccc tccaaagcaa attcttttga ctgcaatata
    13861 ggagttttac tcaatattac tttgtatttt cctgcatatt ttccagtttt atcctttccc
    13921 cattcaatcc aatgatttcc ggaggatata tcaccgatat aaaaatattc cattcccaaa
    13981 gctttaccta ttattgaata aaactcttca actccggaat tcttatcaat caaaatggga
    14041 cattcttcca atgaaagaat atctaaataa aaagacttta gactcaatgc tatttcttcc
    14101 gctgtcgccg tttgccctac atccacgtta aaagttccga cacgaataga agtatctatt
    14161 atagggggga ttttttcctt atcattctcc ggagtatcac tactgcatga gaatataaaa
    14221 ggcaatatta taagcaaaat attcagatat ttcatagcta ttaattattt agaatcagac
    14281 cctctatcat ttaagatatc atctactgat ggattgtagg cattaccttc acaatgataa
    14341 cttactgtag gcagactggt taatattggt tttaatgcgg aaaggtcagt taatttttca
    14401 ttacctttgt ctgatttgtt tccacttctt atccctatat taattagttt cactgccgta
    14461 agcccttcta atccattcaa gtttgtaagg ctgggatttc ccataatata aagattcgtc
    14521 tttatttcac ttaaattttt cagaccggtt attgaagtca acattggatt atttctcaac
    14581 caaaaattac cgccaatctt ctttagattt tttagaaaat caagatttcc cagaagacta
    14641 ttaccatcta cctcaaggtt tgtacccacc tcggtaatgt ttgcaagcat agatacatct
    14701 gtaatatcac tgcctgatgt cccatttcca attcgtaatt taccggtcac agaagtgtat
    14761 ttcaactgta aattatcgat tgccttttga tttggcagca gcaaatcgcc tacataaata
    14821 tgttctatca ctccttcttt ctgtggaatc gttacattaa ccgtacttgc aagagaacgt
    14881 acatttgcat tattcaccca atacaaatca atctcgtagt ccgtgcccgg tttcaacttt
    14941 tcaattgaat atttagttat agcaggatca acgatatcaa tcagtccgtc tccgggatta
    15001 tatacaatga catacttctt tacttccccg tttggtacat cccatgataa agaaatactt
    15061 tcttcaaata cctccgttgt caaccctgtt atcggatctg gttgatttat cccgtcttta
    15121 tcatctccac atgaggctaa caataaggac atcgataaaa taatgatgaa gtttaaaata
    15181 tctttcatga ctctattttt attttttata ttaatattcc ggattttgtt taataacgac
    15241 aggatttgca ttaatctcgc gttgcggtat aggatatact aattgataat ctttcaccgt
    15301 gaacttactg ctctcctggc tgctattatt cattgtttcg acagcagtac ctgtacgaat
    15361 caaatcgaac cacctatggt tttcaaaagc gagttccaat cttctttcat ccgcaatggc
    15421 ttttctgaaa cttgtttgat ccggcaaatc gtctgaatca taagtagata ctcctgcgcg
    15481 cgaacgtata ctgttcagaa gcgtaaaggc ctcacctgaa tcgtcacccg tatatcctat
    15541 ttcatttaaa gcttctgcca gcataagaac tacatccg
//
