LOCUS       c00021_gnlPro..        14852 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKEDMBFI_21.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:51:12
            Original ID  :: gnl|Prokka|NKEDMBFI_21
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 47025
            Orig. end    :: 61877
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14852
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[57025:60465]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14852
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14852
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(47..1600)
                     /locus_tag="ctg21_41"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVSDLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
     CDS             complement(1634..3370)
                     /locus_tag="ctg21_42"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLSGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPI
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNQVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKAVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPGGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             complement(3391..3720)
                     /locus_tag="ctg21_43"
                     /transl_table=11
                     /translation="MRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVKNLERKKYVKAK
                     RYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKISTDELKEIIDMI
                     EKGRE"
     CDS             4360..5256
                     /locus_tag="ctg21_44"
                     /transl_table=11
                     /translation="MKMLSFILVLLLGGGMPAGNLLASDKEQNSHYITVKNSRDLQAYF
                     RYAPDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDET
                     IDRTTTGKGKVSDYTYAELQQFNLVDRNGNVTTFKIPTLKECLEWSKDKTILNLDIKDV
                     PLEVMADFIETEKPVNVIYTVHNAGQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPW
                     KQVMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYQSEISTRPD
                     VIETDYPYLFQGLDLTK"
     CDS             complement(5327..5482)
                     /locus_tag="ctg21_45"
                     /transl_table=11
                     /translation="MWEKKRNLYKQLKAVSRQPLTNFVNLKSNTIMKKPHCKDTLVKSV
                     CQAFCR"
     CDS             complement(5507..6604)
                     /locus_tag="ctg21_46"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDTPILFYF
                     KGNTDLDATRIISIVGTRNATKYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRVGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAAATPVQMELFSASEQNPVLAIMRTRNEIHINELASVLEMPVHQ
                     LSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(6601..7008)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_47"
                     /sec_met_domain="HBT (E-value: 5.3e-09, bitscore: 28.2,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.1e-09, bitscore: 30.6,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLRSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             complement(7008..8279)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_48"
                     /sec_met_domain="Peptidase_U32 (E-value: 1.1e-68, bitscore:
                     222.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKNLNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSR
                     SSNNFTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAAD
                     VAAMNYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQ
                     QITGPKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDS
                     NIELDIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRA
                     YCNDTFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIK
                     YFDKIGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLK
                     VNEKIRPSDRLYKMEKVQLEKVFE"
     CDS             8732..9679
                     /locus_tag="ctg21_49"
                     /transl_table=11
                     /translation="MCKRFGADMVYTEFVSADALIRSVNKTQQKLNVADEERPVAIQIY
                     GRDVPTMVEAAQICEAAHPDILDINFGCPVKRVAGKGAGAGMLRNIPLMLDITREVVKA
                     VNIPVTVKTRLGWDADNRIIVDLAEQLQDCGIAALSIHGRTRAQMYTGEADWTLIGEAK
                     NNPRIQIPIIGNGDVTSAEICKQRFEQYGVDAVMIGRGSIGRPWIFREARHYLDTGETL
                     PAESFSWYLDILKKQVEQSVERLDERRGILHIRRHLAATPLFKGIADFKQTRVAMLRAE
                     TVEALFDILDSIPDKFHTGYGFQSDSQVSESTDC"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_50"
                     /sec_met_domain="Fer2_3 (E-value: 4e-26, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.2e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_51"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.8e-60, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.3e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLSEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12766..13440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_52"
                     /sec_met_domain="SucD_FumR (E-value: 4e-67, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             13700..14653
                     /locus_tag="ctg21_53"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKALDYKIGNKLL
                     FSYNYTTVYPAPGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
ORIGIN
        1 ttctatattc catatttata tcgattatat tgttcagcta ttctatctat tccaagtcgg
       61 cgtctttcaa cattttccgt gctttctctt tttcttcctt actcagggcg agcgtatcga
      121 gtttagcacc gcttttacgc aattcctttt ctttttccct ggctttttta atatgttcct
      181 gcatcttctc gcgcctcaaa cgttcatctt ccggcatttg cggtaactgg gcgaccaagg
      241 cacgcagatc ggagacagcc aacttcgtct tcttcccatc gggagccaac atcgtcactt
      301 catcggcatt ccggaaaaag gcatcttcac aaaccgcttc caagaaaggg cggtaattat
      361 aaagatactt ttgcgacttg tctgtcttca tataggctgt caggtaagtg tatctactga
      421 aaatcgtctt ttgcaatttt tcctcctgct gaaagagtcc cggatcgaca tcccagtatt
      481 gtgtactgat cttatacagg aagtgcaact gggttgggtc ttccttccat gcggcataat
      541 acagcttttc cgcttcgggc caacggccgt ccctttccaa ggcatcacct cggaaggtcg
      601 tcaacatatt aactaggaac tttttcggct gcatattcgt ttccgccaga tcgaaaagct
      661 cataagcccg tttacggtcg tatgtttttc ccagggaagc gccatacaac atgactgttt
      721 ccacatccgt cgaatctatt tcataggcct tctccagcag ctcgacccca tcaagtgcat
      781 gaccggacat atagcgggcc gcccccgcat atttaagatt caaaaaagaa gaatcgccat
      841 cggccaatag accggtatag actgaatcag cctgcttata atctttcgtc atatagagag
      901 ccatcccttt actctgccgt atctggctgt tatccggatt atagaacaag gcggtatcgc
      961 acacctgcaa agctccctgt ccgtccccca tccgcaataa cgtatttatc agagaagatg
     1021 ccacacgcac attttccggg ttcagctcca aagcacgggc atacaaagaa agagcgatca
     1081 tcgtattagg accggtccct cttttaatat ggcaatcagc cagcccagtc aggatagaag
     1141 gattttcacc ttcgatggaa gcaagtatat gatagtgttc cgtcgctcga ccataatctc
     1201 ccaactgata atagagacgc gccaactgat agttggcata gaaattcatg ctgtcggttc
     1261 ccaatacttt acgataacat tgtttagctt ccgctatcct tccgaaattg atcgcattcc
     1321 tggcaacggc attcaatgca tccacattgt tcgtatccat cttcaagcaa tgagaaaagc
     1381 actgataggc ctccttatag cgcaacagtc cctcatacgc ctgcccgatt gccgacattg
     1441 tagcataatc ggctgaatcg gcaggagtaa gactatccgc acgtgctaca acttcctgaa
     1501 attgtttttt attgaccaat tcctgaagat taagactctg cgcctgtccc caaagggaca
     1561 gtacgcaaag aaacagtaat agagaaaact tacatttcat aatggtatcg tattaatgac
     1621 cgattctggt caattactgc aaacggaaag taaccggaac cgtatatttt acggctacag
     1681 ccatattgtt ttgtacgcca ggattccatt tcggcatttc ccggatcacc cggacagcct
     1741 ccctgtccag cgaaggatcg attccacgga tcacttcaat atttttcaaa cttccatccg
     1801 tgtcgacaac gaaagaacaa gagacacgtc cttgtattcc attctcctga gcaatagccg
     1861 gatattttat gcgtgttgcc agatatttca acaacgaagc ctgtccaccc ggaaattccg
     1921 gcatctgttg cactaccgta aagacacgac cggacgtatc gacttcttta atctgcctct
     1981 gcacgatacg agaggatgtt tttttctttc caccggaaag ccggaaagtt accggtaccg
     2041 tatatttgac attaaccgct ttgccccgct gttttcccgg cgaccatacc ggcatggagt
     2101 ttatcacacg caaagcctcc tcattcagtt ccggacttac cccacgaatc acttctgcct
     2161 ccgagatagc cccgtctttt ccaacaacga aagaacagct aacccgtccc tctataccat
     2221 ttttaacggc cgattccggg tatctgacat tcgtcgccag gaatttcagc agagcaccct
     2281 gtccgccagg gaattccggc attacctcca caacggtaaa cacctggtta cgggcacgtc
     2341 tggcagcctc aattccttcc tccgatagca catactcctc acgtttttca gcaggagaag
     2401 catcaccgac aaaagggaac ggcaagatag cctccggtag taaaacatcg gcaaacgtgc
     2461 tttccgtcag ttcgtccgtg atccgggcca atgcatcgac attgctcaaa atcagcaagg
     2521 cgcccacaat cggtataaaa atcaggtatt tcgtcctccc tatgctccgg gaacgtttct
     2581 tattcatcat gctgatccga tttttcagat gcagcatatt aaagttatta gataaagagg
     2641 tcaccgatct attggtatgt gccaacccca aaaggtgata ttggtagcta cgactgtcat
     2701 agcccgattc aagtaccgta tcatccgcca aatattccag attatgacgt acctctcttt
     2761 tcaacagcca gacaaacgga ttcacccaac agatgataca aaccaattcg caaataatca
     2821 cgtcaatcga atgccactgg ctgacatgcg tacactcgtg taccaaaatc tcatcgatct
     2881 ctttctcgga atggctgtcg ggatgcagaa ataccagccg gaaaaaagaa aaaggaccgg
     2941 ccggtttatt caacagatgt acacgtacgt tacggatcaa agtcacttcc gaccgccgtg
     3001 ccagtaacaa gatgctgctc aactgtacta aaaaacggaa cgataaggca attacaccgc
     3061 tccaataaag ataagaaata ccggaaagta acaaatcatg ccaatttgtt tggggaacat
     3121 tgccgggggt tattgtcgtt tcaggcaaaa tggctgaata catttgtatg acttccacta
     3181 tcggcccctg ctcccggatc caatcctgaa tattcatcag cggataaagc aatgacaccc
     3241 cgaaaaatgc caacaagatg gtacggcgta gtttaaagaa ggtgtcctta taaaagaaca
     3301 gccggtagaa ggcataaagg agtataaaag ctacatttac cttcaagaag taggcaaatt
     3361 ccggtgtcat ggcattatgt atttaacagt ttattctcgt cctttttcaa tcatatcgat
     3421 aatctctttc aactcatcgg tcgatatctt ctgttcctta gcaaaaaagg agaccatttc
     3481 cttgtaagaa ttctcgaaat agttgttcac cacacttccc ataaacgtcc gtttatattc
     3541 ctcctgtggg atcagcggcc tgtattcgta agtatttccg taacgtttcg ctttcacgta
     3601 tttcttacgt tccagattct tcacaataga agcgagtgtc gtataaggag gcttaggctc
     3661 ttcatacttc gccaggatgt ctttgataaa acacggctcg atctgccaga tccagcgcat
     3721 tacatcctct tcctgtcttg ttaatctttc catgtttcta tattattttt tacgatcgca
     3781 tcgcaaattt acgaatatat cgtaaataca caaggaataa tgcattaatt tgtattaata
     3841 attaataatc catcatctat tcgctgcata cgccaaaaag gaatttatct ataagcagcc
     3901 acaccaaaac attccccccc tatattaatt aatgatttta tatactccaa gggaacattt
     3961 tttaagcatg ggatttcact tttttcgacg ataaaaagta tttgaattag cagtttttac
     4021 atgtaatctg tatagtttag aaataaccaa cattttttga caaaatagct attaaaactt
     4081 aacatatatt atccatgaaa ggcttgacaa acaagcttgg ttagtgtact tttgtactgt
     4141 ggttttttca taatagtatt agatttaagg ttaacaaagt tggttagggg ttgtcgagat
     4201 gacaatcctt aattttttat atacctgcct cttcctttgc atatattgtt tccggtcata
     4261 ttttcatatt tttgtagcgc tttttatagt acgccactga taaaaaagtc ttacttttaa
     4321 gccgcataat tgataaggaa tctatataaa tacaatatca tgaaaatgct atcttttatt
     4381 ttggtactcc ttttaggggg gggtatgcct gccgggaatc ttttggcttc agacaaagaa
     4441 caaaattctc attacattac tgtgaagaac agtcgggacc tgcaagccta tttccggtat
     4501 gctcccgatc gcccgattgt aatcagcgga catcgtggtg gaatgctgga cggctatccg
     4561 gagaactgca tcgaatcatt cgaaaagacc ctgtcctata tggaatcgtt tttcgagata
     4621 gacccacgtt tgacaaaaga cgggataatc gtattgatgc acgacgaaac catcgaccgg
     4681 acaactactg gaaaaggaaa ggtttcagat tacacttatg cagaactgca acaattcaat
     4741 ctggtggacc gaaacggcaa cgtgacaacc ttcaaaattc caactttaaa agaatgcctg
     4801 gaatggagca aagacaaaac aatcctgaat ttggatatca aggatgtacc tttagaagtt
     4861 atggctgatt ttatagaaac agaaaagcct gttaacgtaa tatacacggt acataacgcc
     4921 ggtcaagccc gctattatct tgaccggaaa ccggatgcga tgttttcttg ctggtgtaag
     4981 aatcgggaag aattcgataa ttatgaaaaa gccggcatcc cctggaaaca ggtaatggct
     5041 tatgtcggtc cgaagatgaa gcctgaacag caaccactgt atgacgctct gcaccgtaac
     5101 ggagtcatgt gcatgatttc cgttgctccg acacatgatc gcgcgaaaac ggaaacagag
     5161 aaaaccgccg gttaccagtc agagatcagc actcgtcccg acgtgatcga aacggactat
     5221 ccgtacctgt ttcaaggact cgatttaaca aaatagcgca gtttaaagga ctctttatag
     5281 ccgattaaaa tctttttgct atttatgctc atctgattaa caagtattag cgacaaaatg
     5341 cttgacaaac gctcttgacg agtgtatctt tgcaatgtgg ttttttcata atagtattag
     5401 atttaaggtt aacaaagttg gttaggggtt gtcgtgagac agcctttaat tgtttataga
     5461 ggttccgttt cttctcccac atacaaatcg tatacgaaaa agccggtcag gacagcttat
     5521 agagatttcc cggcaacgct tttaccttcc cgtttatttc cagttcgaac aatagcatag
     5581 agagttgatg taccggcatc tccaacactg aggcaagctc gttgatatgg atctcattcc
     5641 gcgttcgcat aatggctaaa accggatttt gttccgaggc ggaaaacagc tccatttgaa
     5701 cgggagtagc cgcagcttgg atatcccaac aaagagcgga gagcagatcg tccgcagaag
     5761 tgatcaggcc ggctttgttt tgtcggatca aattgttgca tcctttggaa tggctgtcac
     5821 cgacgcgccc tggaaagcta tagacatctc ggccataaga gaatgcaata tcggcagtta
     5881 ccaaagagcc tcctttttca gccgattcaa ccacgatcgt acaatccgag attccggcga
     5941 caatccggtt ccgccggagg aaatttggac ggtctggttc tgtgccgctg ggaaaatcgg
     6001 tcaacagacc gcccgattcc agcatttcga cagccgtatt ccgatggcag gaaggataga
     6061 tacgatccaa gccatgcgcc agcacagcaa cagtcggaag tcggttgtac aaggcgttcc
     6121 ggtgggcaca gatatcgatg ccgtaagcca atccactcac gaccaacaag tccgggatca
     6181 cttttgccaa gtcttttata agggattcgg taagctcccg gccatatttg gtcgcgttgc
     6241 gagtacccac aatactgatg atacgggttg catcaaggtc agtatttccc ttaaaataga
     6301 aaagtatagg ggtatccgga cattctctca agcgcaccgg ataatctgta tcagtcagat
     6361 aataacagga aatattgttt ttctcaataa aagccaactc tttttccgcc cgttgcaaga
     6421 tttccgggcg tttgatttcg gcagcaatat tgctgccgat accagggatc cttcctaaca
     6481 actgttgctt ttcagtaaac acagcctctg cttctcccaa agcctgcagg agatggcgcg
     6541 ccaggatatc tcccacgccg tttatcatag taaggccgat ttggtaaatc cgtttgtcag
     6601 tcatgtatgt tctattcttt ttagcatttc gtcgaaatat tcaccgcgtg tcaactttcc
     6661 gttctcaacg ataaccgact cgacgattcc tttcgtcgcc aatgcattgt cagaagccct
     6721 atatatatcc tgctcgaata cgagcttgac tcctttttta tagacattga ggcaagagat
     6781 atagctgtcg ccgctcctga gcgaggtctt atactggatt tctacccgcg atacaaatcc
     6841 gtcaacccct ttttcgtgca tcttcccgaa gttctcacca agcgactcca agaattcatg
     6901 tcgagtatgt tccatataat gctgataatt ggagttgttg accactcctt gcaggtcgca
     6961 ttcgtagtca cggaccttgt ctgtcagttt aaaaatatac tctttcatta ttcaaatacc
     7021 ttttcaagtt gcaccttttc cattttatac aatcggtcag acggccgaat cttctcattc
     7081 accttgagag agaaccgttc acctttaacg gtctcgtcca ccggcttcaa gtccacacgg
     7141 atttcttcta tcgtttgcat aaccgcaccc gttgtcggtc cggtaattag gatctcatca
     7201 cccactttca ggttaccgga ttccatttcg aactccgcca cgccgatctt gtcgaaatat
     7261 ttgattcctt tggcaacata cactttcttc ttagtcgcac cagagccata tttgctactc
     7321 cactcaccca accgttgccc caaataatag ccgtcccaga atcctcgatt aaacacacta
     7381 cgcaggcgtt cgtcccaagc ggcaaccttc ttttcatcga acgtgtcatt gcaataggca
     7441 cgcacagctt ccttatagca ttcggtcacc agacggacat attcgggacc gcgagcacgt
     7501 ccttcgatct tgaatacccg tacacctgca tccatcatct tattcatgaa atgaattgtc
     7561 ttaaggtctt taggcgacat aatatactgg ttttcgatat ccagttcgat attgctgtct
     7621 ttatctttta ccgaataagc acgccgacaa atctgcatgc aagctccccg gttggcggaa
     7681 gcgttcattt cgtgcaggct caggtaacat ttaccggaaa cggccataca gagagctccg
     7741 tgggcaaaca tttcgatacg gatcagttct cctttcggtc ccgtaatctg ctggtcgacg
     7801 atctgccgat agatttcatg cacctgtttc aaattcagct cacgcgccaa gacgacaaca
     7861 tcggcaaaac gggcatagaa tttcagtgct tccgcattgg aaatgttgag ctgtgtggaa
     7921 agatgcacct cctgtccgat gctgttggca tagttcatag ctgccacatc ggccgcaatg
     7981 atcgctgaaa cttccgcctc tttcgctgca tcgataatct cgcgcatcag aggcaggtct
     8041 tccccataaa taaccgtatt gacggtcaaa tagctcttaa taccgtgctc acgacaaagc
     8101 gcaacgatct tgcgcaaatc gtctgtcgta aagttattgg aagagcgcga acgcatattc
     8161 aatccttcga taccgaaata gatagaatcg gctccccctt ggatagccgc catcagcgat
     8221 tcgtacgaac cgacaggcgc cattatttca aaatctttct cgttcaagtt cttatacatt
     8281 tactggttcg ttcgcaaagg taggaataat atccgagaag aattgcatgg gtatccgttt
     8341 ctcagagcat caaaatcgtg atcaaatacc attttctata aagatttgca aaacaaccat
     8401 catactgtca ttgttgtcct ttagaatctg ttattcaata ccttaagaca tgatagtttc
     8461 tatttttaac tatcatgcta ctatcatgca actatcatga tttcagctta tcattttatc
     8521 tatatcattg acagtatgac atttgtactt tttattgatc aattactaca ttttttagta
     8581 gatatccttt tatccctgtt tttagcagga aatcagtacc tttgtccccg tcattgataa
     8641 tataaatatg aaaataggta caatagattt aggcgaacgc cccgtcttct tagctccgat
     8701 ggaagacgtt acagatattt ctttccggtt gatgtgcaaa cgctttggtg ccgatatggt
     8761 ttataccgaa ttcgtttcag cagacgccct gatccgcagt gtaaataaaa cacagcaaaa
     8821 gctgaacgtg gcggatgaag aacgtccggt cgccatacag atatatggcc gtgatgttcc
     8881 gacaatggtc gaagccgcgc aaatttgcga agccgctcat ccggacattc tcgatatcaa
     8941 tttcggttgt cctgtcaaac gagtggcagg caaaggagca ggcgccggca tgctgcgcaa
     9001 tattccactg atgctggaca tcacccgtga agtcgtcaaa gcggtgaaca tccctgtcac
     9061 cgtaaagacc cgcttgggct gggatgccga caaccggatc atcgtagact tggccgaaca
     9121 gctacaggat tgcggtatcg cagccctttc catccacgga cgtacccggg cacagatgta
     9181 cacaggagag gcagactgga cactgatcgg cgaagcaaaa aacaatcccc gcatacaaat
     9241 tcccatcatc ggcaatggcg atgttacttc cgccgaaatc tgcaaacaac gtttcgaaca
     9301 atatggcgtg gatgccgtta tgattggccg gggcagcata ggccgcccct ggattttcag
     9361 agaagcgagg cattatctgg atacaggcga gacattacct gccgaatctt tttcatggta
     9421 tctggacata ctgaaaaagc aggtggaaca aagcgtggaa cgtttggatg agcgccgggg
     9481 aattctccac attcgccgcc atttggctgc aactccgctg tttaaaggta ttgcagactt
     9541 caagcagaca cgcgttgcca tgctacgtgc ggaaacagtg gaagcattat tcgacattct
     9601 ggattctatc cccgacaaat ttcatacagg atacggattt caaagcgact ctcaagtgtc
     9661 agaatcgacc gattgttgat ataataacag tgtgaatccg cacacagtgt caattttaaa
     9721 acaaaaagta gcaaatttgc aataaaatgt aattacaaac tcttgcgtat tcagtaaata
     9781 tactttatat ttgcagtgag tttttttcat agtattttag atctaaggtt aacaaagtct
     9841 ttgcagagag ggaatcgaga gactgtttca ctggaaagca acaaaaaagc cgcatccatt
     9901 tttattatag ggagtgcggc ttttttgtgg gtttgaacga acataaagaa aacccgttgc
     9961 caatggcaac gggcttttcc atatacatat atataatgta ttagtcttgt aacttagcag
    10021 agatgaactc gcggttcaag cgagcgatgt tgctaacgga gatgttcttc ggacattcca
    10081 tttcgcaagc gcgagtgttc gtacagttac caaagcccag ttcatccatc ttagcaacca
    10141 ttgcttttgc acggcgagca gcttccacct taccctgagg caaaagagcc agctggctaa
    10201 cctttgcaga gacgaacagc atagctgaac cgttcttaca agcagcagca caagcaccac
    10261 agccgataca agcagcagca tccatagcca aatccgcatc agccttagaa ataggaattg
    10321 cattagcatc aggaacccca cctgtgttta cagaaacgaa accacctgcc tggataatct
    10381 tatcataagc ataacggtct accatcaagt cgcggattac cgggaaaccg gcagaacgcc
    10441 acggctcgat cgtaatcgtc tcaccatcat taaaacgacg catatagagc tgacaggttg
    10501 ttgcacctgt tgccggtccg tgcggatgtc cgtttacata caatgaacac ataccgcaga
    10561 taccttcacg gcagtcgtgg tcgaatacga taggttcttt gccttcgcta accaaacgtt
    10621 cattcaaaat gtctaacatt tccaagaaag aaacactctg attgattttg tcgatttggt
    10681 aagtctcaaa ctgtccttta tctttcggac ctttctgacg ccaaacttta agtgttacct
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc gggtctttgt
    10861 cttcaccctg gtattcccaa caagagacgt acatgaactt atcgtcatga cgcatagctt
    10921 cgccttcttc ggtctgatgt tccgtacgga agtggccacc acaagattct gcacggtcta
    10981 acgcatcgtg tgccatcaat gcaccgattt cgataaagtc agccaaacgc aatgccttgt
    11041 ccaattccac gttcaagcta ttggcctcac ccggaatgaa tacattgctc cagaattcct
    11101 tcttcaggtc tttcaacatt tggatagctt ctttcaagcc ttccgcgtcg cgtgccatac
    11161 cgacgtgttc ccacatgata tgtcccagct tacgatggat agaatcgaca gtttctttac
    11221 ccttcacgtt catcaacttc gcgatacggg cgttaatagc cttttctgct tccacaaatt
    11281 cagacaggtc agtgctgaag cgcggaacct ggatctggtc agacagatag ttctggatgg
    11341 tgtaaggcaa tacaaagtaa ccatcggcca atccctgcat caaagcagaa gcacccagac
    11401 ggttagcgcc gtggtcagag aagttagctt caccaattgc gaacagcccc ggaatagaag
    11461 tcatcaattc atagtctacc cacaaaccac ccattgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtacgga tcatcgttcg tgatctcttc gtacatatcg aacaggttac
    11581 catatttctg tttaactact tccttaccca gacggttgat agcgtcggag aaatccagga
    11641 atacagccaa gcccgtgcta tttacaccga aaccggcatc acaacgttct ttagcggcac
    11701 gtgaagccac atcacgagga accaagttac cgaatgccgg ataacgacgt tccagatagt
    11761 agtcgcgatc tgcttcagga atatccttac ctttttttgt tccggcctgc aatgccttcg
    11821 catcttccag tttcttcgga acccagatgc gaccatcgtt acgcagtgat tcagacatca
    11881 aagtcagctt agactggaag tcacctttca ccggcacaca agtcgggtgg atctgcacca
    11941 tacaagggtt agcaaagtaa gcccctttct tgtagcactg ccatgcagca gaaccgttag
    12001 acgccatcgc gttagtagac aagaagaatg tatttacata accacctgtc gcaacaacga
    12061 ctgcgtgagc ggcaaaacgt tcgatcttac cggtaatcaa attacgggca ataataccgc
    12121 gagcacgtcc gtcaaccttc acaacatcca gcatttcatg gcgtgtgtac atcttcacct
    12181 ttcccaaacc aatctgacgg ctcaatgcag agtaagcacc caatagcagc tgttgtccgg
    12241 tctgaccacg ggcatagaac gtacgggata cctgagcacc accgaatgag cggttatcca
    12301 acagaccacc atattcgcga gcgaatggta caccctgtgc cacacactgg tcgataatag
    12361 agtttgacac ttcagccaga cgatagacgt ttgcttcgcg ggcacggtag tcaccacctt
    12421 tgattgtatc gtagaacaga cgataaaccg agtcaccatc attctgataa ttctttgccg
    12481 cattgatacc gccctgtgca gcgatagagt gtgcacgacg gggagagtcc tgaatacaga
    12541 aattcaatac attgaatccc atttcagcca gagaggcagc agcagaagca cccgccagac
    12601 cagtacctac tacaattatg tccaaacgac gtttgtttgc gggattcacc aatttctggt
    12661 gatttttata atttgtccac ttctcagcca acgggccttg aggaatttta gaatctattt
    12721 gagtcataat gttttatttt caaattgaaa aaataatatc cgaaattaag cacctacacc
    12781 gttcaggtag aagataactg tgataacagc gaataagcca caaataatag tggcaaccca
    12841 tttagagata cattcccaac ggcttaacca aacggtattg ttccagccaa ttgtgtgaat
    12901 cgcagaccag aaaccgtgag tcaggtgaaa ccacagagca acgaaccaga tcagatacaa
    12961 caccgtattc acgacattgc cctggaagta gaaattgata aacgctgcac catcctgcgg
    13021 atgaatgtca ccatgaatac ctgccagttc ggcaaacatc atgttgtacc agaactgagt
    13081 aaagtgcaga accatgaaca ggataacgat cacacccaaa acaaacatgt tctgagaagc
    13141 ccattcaaca cctttcggac gagcgttgat ggcataacgg tcgttaccgc gagccttacg
    13201 attctgcaga gtcaagataa tagcatacac gaagtgcacg actacacctg cagccaacac
    13261 caatgtaccg agcaaagcat accagttaga acccagcaaa ccgcaaatca cgttatacgc
    13321 ttcaccagaa aatactgccg caatgttcat acataagtgg aacaccaaga acagaatgag
    13381 aaaaagacct gatatactca ttatcagctt cttcccgata gaagaattaa gtaaccacat
    13441 aagataataa tttaagttat ttaattgtat ttagaaattt cttccaatct atggttatta
    13501 tcgtgcaaag gtatgctaaa tccccatatc acgcaaacga ttaaagaaat atttcatcaa
    13561 ttagaacgct gcttgctggc tggttttatt ttcatcagat atcacaaacg gattgtacga
    13621 aacgaaaaaa tttcgttttt ttgtagccga tacaggcaag gtcttgccgg ataactgatt
    13681 attatttaat tgtcatatta tgaaaactgc tattttttct attggtgttt ttttgatttc
    13741 tctgttctta ggctcttgtc agccttccga aacatcctgt tccgtcgtcg acacggggaa
    13801 agccttggac tataagatag gaaataaact gttgttctct tacaactata ccacggttta
    13861 cccagcccct ggcgttgact cggtctataa acgcagcggt ttcatccatc ctttgaagac
    13921 attgggaggc gaagtgatga ccaattgttc tcccgccgac cattaccatc atttcggttt
    13981 gtggtatgcc tggacgaaaa ccacgtttga aggaaacgag atcgacttct ggaatctcca
    14041 caaaaaacaa ggaacagttc gcttccgcaa cttcgagcac gtatccgaca acggttttgt
    14101 tgcgacactg gaccatgtgg tctaccccga ttctcccgca gaaaaagtag caatgaacga
    14161 acgcctggag atcaacatcg ggacaacatc cttaccaggt tattacatcg actatcatac
    14221 cactatccgc ctcgccagcc ccagcccgat caccatggaa gcttaccgtt atggcggcat
    14281 atgcatccgt acgcgcgaag actggaacga tcagacagcc gaaatgctca cctcggaagg
    14341 cctttcccgc gacgaagctg acggttcgag agcccgttgg tgctattacc aagggaaagc
    14401 cggaaacgaa aaggcctgta tcctaatcgt tgcctcccct tccaacctga actatcctga
    14461 gcctttacgc gtatgggaca aaactgtcaa caagcctgcc ggtgacgtca tgtggaattt
    14521 ctcaccgacc aagcagaagg cattcacctt ggaacccggt aaagaactga gcctgtctta
    14581 ccgcatttat gtattggaca agaacatcaa cgctactacg gcagaagtgc tgtccgattt
    14641 cgaacgtgat tgaatttcta ctaaaacaaa ctgacaattt gcagggcaag gtaaacaaga
    14701 aaagggaaaa gggcttgttc tcctatatca tcaaagacaa ggctctttta tgtaaataca
    14761 gctacaaatc aatgaaaaac acgtaataaa acttgcccaa tacccccatg tgcccgcccc
    14821 cgacacccgg atcttacgct cttatagatc cg
//
