LOCUS       gnlProkkaKJBMLOPJ_71    9214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KJBMLOPJ_71.
ACCESSION   gnlProkkaKJBMLOPJ_71
VERSION     gnlProkkaKJBMLOPJ_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 23:25:35
            Original ID  :: gnl|Prokka|KJBMLOPJ_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9214
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9214
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2636:6525]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2637..6525
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(19..888)
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MKNINEKLALLQGKIENNSPIVIMIIGLGSVGLYLLDYLLSLSDP
                     QLRIVVVGRNSEKMLKDVNIVKTAATIRKQLQSKIFIESECDLDSIQTISEILKKHQPD
                     FIINSSRVYSGLKYGSISWSKLRAYGVWTPLSMRYAKNIMAAYELADCDAITINTSYSD
                     AVIPWLKSAGKTFFDFGSGNLNHLIPRIKFYIADKMGIDNLSNIDVTLAVSHFHDVVIS
                     KEGHAEGENVLLDIRYQGKKCNYDTKDLLRSCMIPMPVDQKRNMMNASSNFDIIYSILD
                     FKRFGITV"
     CDS             complement(885..1634)
                     /locus_tag="ctg71_2"
                     /transl_table=11
                     /translation="MKVLIVTVAGISSRFNRDTSRNVLKCLYYEDSPTHSLLYQIVCKV
                     LDFERVIIVGGYLYDELVMYAEKYLSNLGPQIELVYNAHYKDYGSGYSLIKGVERVPEV
                     ANEIIFVEGDLYFDNESFSLVKKSLYDVITVNHEFITSEKAVALYVDEIDKVHYIYDTN
                     HSLLSIPSPIKAIYNSGQIWKFTSLSKLNSVISLLSPKQIQGTNLEIIQTYFDNIPVSD
                     LNFIALNTWFNCNTVADYQKVNSLLTK"
     CDS             complement(1631..2623)
                     /NRPS_PKS="Domain: NAD_binding_4 (83-198). E-value:
                     7.9e-09. Score: 26.8. Matches aSDomain:
                     nrpspksdomains_ctg71_3_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     159.2; E-value: 2.6e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.4e-08,
                     bitscore: 21.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.6e-11, bitscore:
                     31.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLYVISGVTGMTGSELARQLLKAGHSVIGFDNFFASSLDSVQD
                     IMESSHFHFFEYDLNNESQMSHVKEGILRVRNDFAQVIYINCAAVVHTEHFYEVEHTFQ
                     TNVLSMRDFLNQAISLDAAIFINCSTSEVYSMQSWNENGGVKEDDYLVLASAEHSQRTS
                     YAVGKLLTEFFLKDAVDKGYIRGCSIRFANVYSNHERFAKHIIPHIINSLLEDKEVILL
                     ENSKKNRRSFLHNIDSCRAVLALMQSDMALDGTVYNVATDEEISILDLVSMIGSKLDIY
                     NPTIHFEGYRASDPERRILNTDKIRKRTGWVPIVSLSEGLDMCVESLKK"
     aSDomain        complement(2030..2374)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_3_NAD_binding_4.1"
                     /evalue="7.90E-09"
                     /label="ctg71_3_NAD_binding_4.1"
                     /locus_tag="ctg71_3"
                     /protein_end="198"
                     /protein_start="83"
                     /score="26.8"
                     /tool="antismash"
                     /translation="YINCAAVVHTEHFYEVEHTFQTNVLSMRDFLNQAISLDAAIFINC
                     STSEVYSMQSWNENGGVKEDDYLVLASAEHSQRTSYAVGKLLTEFFLKDAVDKGYIRGC
                     SIRFANVYSNH"
     CDS             complement(2637..3371)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Metallophos_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="Metallophos_2 (E-value: 2.2e-26, bitscore:
                     82.3, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKLIILSDIHANLTALLAVLDDAFSKYQPDAIVSLGDIVNYGMR
                     PNEVINALNQISCPVIVNLMGNHEKALLDLDLSHFSTERGKRLLEYTSSVLSDSSYSYI
                     QNRMNQKGFFSINLSGKNILFLHGDIADPYWGKLLPEKIHDIRYSTYDYVFSGHTHQPH
                     YMESYFKVDRPDLRNKKKTVFINPGSVGQPRNQNPRAQYVYIEVDSGSVHFNAVSYDIE
                     SERNLYPDGIDPFYKDRILTGI"
     CDS             complement(3364..4494)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 70.6;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.5e-22, bitscore:
                     69.4, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-21, bitscore:
                     64.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSVEKIYDTFLHHGVDFFTGVPDSLLKNICAYITDHAPRGKHII
                     AANEGSAVGIACGYYMASGNVPLVYMQNSGLGNTVNPLLSLADEKVYSLPLLLLVGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMKIPFIILDTDEDEALAQIHDAVVSAKSRSIPHAIV
                     IRKDTFGKYKLRQEALNDYPLSREEALMQVVDHLGDNDIVVSTTGKLSRELFEYRESKG
                     QGHARDFLTVGSMGHSSSIALGIALEKPDRRVYCLDGDGAFIMHMGAVSNIGDLSPKNY
                     RHVLFNNGAHESVGGQPTLGFRLDIASIAKGCGYAHVLTASDKEGLSCALEKLSGLSGP
                     VLLEIKVRIDSRDDLGRPTTTPVENKEHFMDFITNG"
     CDS             complement(4506..5807)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 214.1;
                     E-value: 3.9e-65)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_6"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-12,
                     bitscore: 37.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 9.2e-123, bitscore:
                     398.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 4.6e-65, bitscore:
                     208.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKIYVGMTADIMHPGLIHIIHEATKYGDVIVGLLTDKAIAEHK
                     RLPYLTYDQRKEVVENIKGVFEVVPQEDWSYVPNLEKLKPDYIIHGDDWKTGPLREVRE
                     QVFEVMDAQGGKVIEIPYTRGINSSSLDKDIKAIGTTPDVRLKSLRRLIQAKPVVRILE
                     AHDGLCGLIIENLEVQKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKVGLKKNSLFGTDAIQTQDS
                     IEGFCDKIRAGKNAQVTGDFMIIARIESLIAGKPMSDALERAYAYVQAGADGIMIHSKD
                     KSGEDIREFCRTFRKEYAHVPIVVVPTTYDHVHESELHEWGANVVIYANHLLRAAYPAM
                     MNVARTILENERAEEVRPLCMPIKEILELIPGTK"
     CDS             complement(5827..6525)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_7"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.6e-14, bitscore:
                     43.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGLGTRFGHYTELVPKGFVEVGGKPMIIRSIETLLSCGIERII
                     FGTGYKKEAYEALQADFPQIETCFSPRYADTNSMYTLYNTRDVIGDDSFLLLESDLVFE
                     RKAILSLLDDEFPDVMLVSSLTKFQDQYYVEYDRNHILTSCSVDKNALEAKGELVGIHK
                     LSNTFYRRMCADYATILESQPKLGYEYELLRMSRSVSPVRVLRVEGLKWYEIDDEADLS
                     YAEEHIIRYC"
     CDS             complement(6539..7822)
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MIRSFLSRSPLYVLALYASVLIFLVYTCAYAYRKPFTAAIYEGEI
                     LWGFDVKILYVLSEIIGYALSKFIGVRILPSMKAGHRIYYIIGLLTFSEVALLGFALLP
                     VPLKVCSIFLSGLPLGMIWGVIFSYIEGRRISEILNVGLSVALIVSSGLVKTLGQFVMD
                     NLHVSEYWMPFTTGLLVYPVMLLCSWLLNQIPAPNEQDIIQRTKRAPMDGKDRRKFLRQ
                     FFWGICMLVVFYGALTVFRELRDSFAADIWKELHIEGAMIFTQTEVPIAVFVLVLMFLI
                     VFVRNNRLALNIIYCIAVTGGSLMVFSTLLYVYGFLSPIWWMILSGLGLYMGYIPFTYL
                     IERLIASLRVVSTAVLIIYLADSFGYLGTTGVFMVKNFVSADISWTVMLMRTALFSGFV
                     SILSIFAIYCYFKQQLNSLILIPSEIHD"
     CDS             complement(7819..8304)
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MNTLTSQIEQLQSLAHELLYLGVDGAPIYTDHFRQLNKEVLEQSD
                     ALYPQRGATPEEEANICLALLMGYNATIYNQGDKEEKKQVVLNRCWDVLDQLPATLLKC
                     QLLTYCYGEVFEEELAKEAHTIIESWSNRELLKAEKEIAESLNNLEANPYPYSELHE"
     CDS             complement(8308..8832)
                     /locus_tag="ctg71_10"
                     /transl_table=11
                     /translation="MSEQQKYWFAARTRDKQEFAIRDSLEKLKTELDLNYYLPTQFVIR
                     QLKYRRKRVEVPVIKNLIFIQATKQDACDISNKYNIQLFYMKDLLTRAMLIVPDKQMQD
                     FIFVMDLDPNGVSFDNDHLSVGSRVQVVKGDFCGVEGELASEANKTYVVIRIAGVLSAS
                     VKVPKSYLRVI"
ORIGIN
        1 tcgctaaaag tttattcctc aaacggttat accaaaccgt ttaaaatcta aaatagaata
       61 tataatatca aaattactag aagcattcat catatttcgt ttctgatcca caggcatagg
      121 tatcatgcat gatcgcagga gatctttcgt atcataatta cattttttgc cttgatacct
      181 aatgtctaat aaaacgtttt ctccctctgc atgcccttct ttactgataa caacatcatg
      241 aaaatgactg acagctaagg ttacatcaat attactcaaa ttatcaatac ccatcttgtc
      301 tgcaatataa aattttatcc tcggaatcaa gtgattgagg tttccgctcc caaaatcaaa
      361 aaaggttttt cccgcagatt tcaaccaagg aattactgca tccgaataag aagtattgat
      421 cgtgatagca tcacaatcag ccagttcata ggccgccatt atatttttcg cataacgcat
      481 agagagaggt gtccatacac cgtacgcacg taatttactc caagatatac ttccatactt
      541 gagtcccgaa tagacacggc tactattaat gataaaatcc ggttgatgtt ttttcaaaat
      601 ctcacttata gtctgtatac tatcaaggtc acattctgat tctataaaaa ttttactctg
      661 taactgtttc ctaatcgtag cagcggtctt cacaatatta acatccttaa gcatcttttc
      721 cgaattacga ccaactacaa caatgcgtaa ctgaggatca gacagactta ataaatagtc
      781 aagtaaatac aaccctacac tacctaaacc aataatcatg atgactattg gagaattatt
      841 ttcaatcttg ccttgcaata aggctaattt ttcatttata tttttcattt tgtcaatagt
      901 gaatttactt tctgataatc cgcaactgta ttacaattaa accaagtgtt caaagcaata
      961 aagttcaaat cgcttacagg aatattatca aaataagttt gaattatttc caaattagta
     1021 ccttgtattt gtttgggaga caataggctg ataaccgagt tcaatttgct taaagaagta
     1081 aatttccaaa tttggccaga attataaatg gcttttatag gagaaggaat agataacaaa
     1141 ctatgattag tgtcataaat ataatgaact ttgtcaattt catcaacata taaggccaca
     1201 gctttctcag aagtaataaa ttcatgatta accgtaatca catcatacaa tgattttttt
     1261 accaaagaaa aactttcatt atcaaaatac aaatccccct caacaaaaat aatttcgttc
     1321 gcaacctcag gaactctttc aacaccttta atcaagctat atccggaccc ataatcttta
     1381 taatgagcat tatatactaa ttctatttgc ggtccaagat tgctcaaata tttttcggca
     1441 tacattacca attcatcata caaataccct ccaacaatga taacacgctc aaaatcaagc
     1501 actttacaca caatctggta caataaagaa tgtgtagggg aatcctcgta atataaacac
     1561 tttaacacgt ttctcgaggt atcgcgatta aaacggcttg atattcccgc aactgttaca
     1621 atcagaactt tcattttttc aaactttcaa cacacatatc caatccttca gaaagcgaaa
     1681 cgatcggtac ccaaccagtt cttttacgaa ttttgtctgt attcaaaatc ctacgctcag
     1741 gatcagatgc acgatatccc tcaaaatgaa ttgttggatt atagatgtct aatttggaac
     1801 caatcataga aacaaggtct aatattgaga tttcttcatc agtagcaaca ttataaacag
     1861 ttccatccaa cgccatatcc gattgcatca gcgcaagtac agcacggcaa ctatcaatat
     1921 tatgtaaaaa agagcgccta ttctttttag aattctctaa taagattact tctttatctt
     1981 ccaataaact attaataata tggggaatta tatgcttagc aaaacgttca tgattactat
     2041 agacattagc aaaacgaatg gagcaacctc taatataacc tttatcaaca gcatctttta
     2101 aaaaaaattc cgtcagcaac tttcccaccg catagcttgt acgctgacta tgttccgctg
     2161 aggcaagtac aagataatca tcttctttca cacctccatt ttcattccac gattgcatcg
     2221 aataaacttc agaagtagaa caattgataa aaatagcagc atcaaggctt attgcctggt
     2281 taagaaaatc ccgcatagac aaaacatttg tttggaatgt atgctccact tcatagaaat
     2341 gttctgtatg tactactgcg gcacaattta tatagattac ttgcgcaaaa tcatttcgca
     2401 ctctcaaaat cccttcttta acatgtgaca tctgactttc attgttcaaa tcatattcaa
     2461 agaaatgaaa atgagaagat tccataatgt cttgtaccga atccaaagaa ctggcaaaaa
     2521 aattatcaaa accaattacc gaatgtcctg ctttcagaag ttgccgagcc aattcactgc
     2581 ccgtcatacc tgtcacacca ctaatcacat ataaattatt catgtcaata tattatctat
     2641 atacctgtta atattctatc tttataaaaa ggatcgatgc cgtccggata caaattccgc
     2701 tctgactcaa tatcataaga cacagcatta aaatgtactg agccgctatc gacttctata
     2761 tatacatatt gcgcacgagg attctgattc ctaggctgtc ccacagaacc aggatttata
     2821 aaaactgtct tttttttgtt tcgaagatca ggacggtcca ctttaaaata agactccata
     2881 taatgaggct ggtgtgtatg cccggaaaaa acataatcat aagtactata acgaatatca
     2941 tgaatcttct ctggcagtaa cttgccccaa taagggtcag caatatcacc atgtagaaat
     3001 agtatattct ttcctgataa atttatagaa aaaaaacctt tctgattcat cctattttga
     3061 atataagaat aagatgaatc tgaaagcaca gatgatgtat attccaacaa acgtttacct
     3121 ctctctgtgg aaaaatggct caaatccaaa tctaataaag ctttttcatg atttcccatc
     3181 aagtttacaa taacagggca cgaaatctga tttaatgcat taataacttc attgggacgc
     3241 ataccgtaat taacaatatc tcccaatgaa acaatcgcat ctggctgata tttagagaaa
     3301 gcatcatcta aaacagcaag tagtgcagtt aaattcgcat gtatgtcaga aagaataatt
     3361 aatttatcca ttggtaataa agtccataaa atgctcttta ttctctaccg gagtagtcgt
     3421 agggcgaccc agatcatcac gtgaatcgat ccggacctta atttcaagaa gaaccgggcc
     3481 ggacaggccg gacagcttct caagcgcaca cgaaagccct tccttgtcgg aggcagtcag
     3541 tacatgcgca taaccgcaac ctttcgctat cgaggcgata tccagacgga aaccgagcgt
     3601 gggttgaccg ccgacagatt catgcgcacc gttgttgaaa aggacgtgcc tgtaattctt
     3661 gggagaaaga tcgccgatat tgctgacagc acccatgtgc atgataaagg caccgtcacc
     3721 gtcaagacag tagacacggc ggtcaggctt ctcaagggca atccccaggg caatggaaga
     3781 actgtgcccc atggaaccca cagttaggaa atcccttgcg tgcccctgcc ctttcgattc
     3841 acggtactcg aaaagctcac gggagagctt gcccgtggtg gaaaccacaa tgtcattgtc
     3901 cccgaggtgg tcgacaacct gcattagcgc ctcctcgcgg gacagaggat agtcattcaa
     3961 ggcttcctga cgcaatttat attttccaaa cgtatcttta cggatgacaa tcgcatgggg
     4021 aatcgaccgg ctcttcgccg agacaaccgc gtcatggatc tgtgccaggg cctcgtcttc
     4081 atccgtatcc agaattataa aaggaatttt catggctttc agaagatcaa gggtaacctc
     4141 gccctgcttc ttatgctggg gttcgtcttt cgtgccgggc tcaccgcgcc agccgaccag
     4201 caaaagaaga ggaaggctgt acactttctc gtccgcaagg gacaagaggg gattcaccgt
     4261 atttcccaga ccggagttct gcatataaac caaaggaacg ttgccagaag ccatataata
     4321 accgcaggca atgcccaccg cggaaccttc attggcggcg atgatatgct taccacgcgg
     4381 agcatgatcc gtgatatagg cgcaaatatt cttcaaaagg gaatcgggaa cacccgtaaa
     4441 gaagtcaaca ccgtgatgaa ggaacgtatc gtatatcttt tctacactta ccataaccgt
     4501 ctgatttatt tagtgcccgg aatcaattcc agaatttcct tgataggcat acaaagcgga
     4561 cggacctcct cggcgcgctc gttttcaagg atggtcctgg ccacgttcat catggccggg
     4621 taagcggcac ggagaaggtg gttggcgtaa atgactacgt tggcacccca ttcgtgaagt
     4681 tcggattcgt gcacatggtc ataagtcgtc ggaacaacga caatgggaac atgggcgtat
     4741 tctttgcgga aagtccggca gaactcacgg atatcctcac ccgacttatc cttgctgtgg
     4801 atcatgatgc cgtccgcacc cgcctgtaca taggcataag cacgttcgag ggcatcactc
     4861 atgggtttgc cggcaataag gctttcgata cgcgcaatga tcataaagtc accggtgacc
     4921 tgggcattct tccctgctct gatcttatcg cagaaaccct cgatactatc ctgagtctgg
     4981 atagcgtcag taccaaaaag ggaattcttc ttcagaccga ctttatcttc aatgattacc
     5041 gcagaaatgc cgtgacgttc cagagtgcgc acagtaaaga caaagtgttc gatcttgcca
     5101 cccgtgtctc catcaaaaat aataggcttg gtggtgcatt caaggatatt gttcaggtcc
     5161 tgtaaacggg tggtaaggtc gaccgcttca atatccggtt tacccttact cgtagagtcg
     5221 gtcaggctgc tggaccacat gccgtcaaag acctcgcgct tatcaccctt ctggacttca
     5281 agattctcaa taatcagacc gcaaagaccg tcgtgagcct ccaggatacg gaccacaggc
     5341 ttggcctgga tcaggcggcg gagggactta agacgtacgt caggggtagt cccgatcgcc
     5401 ttgatatcct tgtcgagcga ggaggagttg atgccccggg tataagggat ctcaataacc
     5461 ttgcccccct gagcgtccat cacctcaaaa acctgttcgc gcacctcgcg caacgggccc
     5521 gttttccagt cgtcaccgtg gatgatatag tcaggcttga gtttttccag attcggaaca
     5581 tagctccaat cctcctgggg aacaacctca aaaaccccct tgatattctc aacaacctcc
     5641 ttacgctgat cataggtaag gtaagggagg cgtttgtgtt cggcgatggc cttgtccgtc
     5701 agcagaccga cgatgacatc accgtattta gtagcttcat gaataatatg gatcagcccc
     5761 ggatgcatga tatccgcggt cataccgaca tagattttct tgttcatata tggaaaagat
     5821 ttgtttttaa caatagcgga tgatgtgctc ctcggcatac gaaaggtcgg cttcatcatc
     5881 gatttcatac catttaagac cctccaccct gagcacacgg acaggggaaa cggaacggga
     5941 catgcggagc agttcgtact cgtaacccag tttaggctgg gactccagga tggtcgcata
     6001 atcggcgcac atccggcggt agaaagtatt ggaaagttta tggataccga ccagctcgcc
     6061 ttttgcctca agggcgttct tgtctaccga acaggaagta aggatgtgat tgcggtcata
     6121 ttccacataa tactgatcct ggaacttggt cagagaagag acaagcatca catccgggaa
     6181 ttcgtcatcc agtagcgaga ggatggcctt gcgttcaaaa acaaggtccg attcaagcag
     6241 caggaaactg tcatcgccta tcacgtcacg cgtattgtac agagtgtaca tactgttagt
     6301 atcggcatag cggggactga aacaggtctc tatctggggg aaatccgcct gaagggcttc
     6361 ataagcctct tttttataac ccgtaccgaa gatgatacgt tcgataccgc aggaaagaag
     6421 ggtttcgata gagcggataa tcataggttt tccaccaacc tccacaaaac ctttgggcac
     6481 aagctcggta taatgcccga agcgggtacc aagaccggca gccatgatca ttgctgtttt
     6541 aatcatgaat ttcagaggga attaatataa gtgaattcaa ttgttgcttg aaataacagt
     6601 aaatcgcaaa aatcgacagg atagaaacaa atcctgaaaa aagggcagta cgcattagca
     6661 tgacagtcca ggaaatgtca gcagaaacga agttcttgac cataaacaca cccgtagtgc
     6721 ccagatagcc gaaagaatcg gccaaataaa taataagaac agccgtacta accaccctaa
     6781 gggaagcaat caggcgttct atcaggtaag tgaaaggaat ataccccata tacagaccaa
     6841 gaccggaaag aatcatccac caaataggag aaagaaaacc gtacacataa agcaatgtgg
     6901 aaaaaaccat taaggaaccg cctgtaacgg caatgcaata aatgatatta agagccaaac
     6961 ggttattacg gacaaacaca atcaggaaca tcagtacaag gacaaaaacg gcaatgggaa
     7021 cctctgtctg agtaaagatc attgcacctt caatatggag ctccttccaa atatcggcag
     7081 cgaaagagtc acgaagctca cggaacacgg tcagggcacc gtaaaaaaca accagcatgc
     7141 agattcccca gaagaattgc ctcaaaaatt tacgcctgtc tttaccatcc atcggagcac
     7201 gtttggtacg ctgtatgata tcttgctcat tgggagccgg aatctgattg agaagccagc
     7261 tgcaaagcaa cataacaggg tataccaaca aaccggtggt aaaaggcatc caatattccg
     7321 acacatgcaa attatccatc acgaattgtc ccaaggtttt caccaaaccg gaagagacta
     7381 tcaaagcaac gctcagcccg acattcaata tttcactgat acgacgccct tcgatatagc
     7441 taaaaatgac accccagatc atacccaggg gaagaccgct cagaaaaata gaacacacct
     7501 tcaaaggaac cggaagaagt gcaaaaccca acaaagcaac ttcggaaaaa gtaagcagcc
     7561 ctattatata atagatgcgg tgacccgctt tcatcgaagg caaaatacga acaccgatga
     7621 acttggaaag ggcgtagccg ataatctcag aaaggacata caggattttg acatcgaatc
     7681 cccaaagaat ctcaccttca taaatggctg cggtaaatgg cttacggtag gcataggcac
     7741 aagtataaac cagaaaaatc aaaacgctgg catagagagc caaaacgtaa aggggagaac
     7801 gggaaagaaa ggaacgaatc attcgtgtag ttcgctgtac ggataaggat tagcttccaa
     7861 attattcaaa ctttcagcta tttctttttc agcttttaaa agttctcgat tgctccaact
     7921 ttctatgata gtatgcgcct ctttcgccaa ctcctcttca aacacctcac cataacaata
     7981 agtcaacaac tggcatttca ataaagtagc aggaagttgg tcaagcacgt cccaacaacg
     8041 attgagaaca acttgctttt tctcctcctt gtcaccctga ttatagatgg ttgcattgta
     8101 acccatcaat aatgccagac agatgtttgc ttcctcttcg ggagtagcac cacgctgagg
     8161 atacaacgca tcggattgtt ctaaaacttc tttgttcaac tgacggaaat gatcggtata
     8221 aataggagca ccatccacac ctaaatagag taactcgtgc gcgagactct gtaattgttc
     8281 aatttgagaa gtgagtgtat tcataactta aatgacacgt aaataacttt tgggaacttt
     8341 gacgctggcg ctcaatacac cggcaatacg aataacaaca taagttttgt tggcctcgct
     8401 ggcaagttcg ccctcgacac cacagaaatc acctttaact acctgaaccc tgctaccaac
     8461 agataaatga tcattatcga aactgacgcc attcggatct aaatccatga caaatatgaa
     8521 gtcctgcatc tgtttatcag gaactatcag catagccctg gtaagcaggt ctttcatata
     8581 aaaaagctgg atattgtatt tattagaaat atcacaagca tcttgcttgg tagcttggat
     8641 gaagataaga ttcttaataa cagggacttc cacccgtttt cgacgatatt tcaactgccg
     8701 gatgacaaac tgagtgggaa gatagtaatt gagatcaagt tcagtcttca atttttcaag
     8761 agagtcacga atagcaaact cttgtttatc tcgggtacgg gcggcaaacc aatacttctg
     8821 ttgttcagac atttacgatt tatacttggg gaaattttcc tttgtttcgg gtgcgcttcg
     8881 cggtttgaac gagacatctt ttctctttca aaccgtcaaa ttttacgaaa cttttttaga
     8941 agttgagaac gaacgaatgt gtttcaaaaa acgttcgttt gattgaacaa aggtaaggag
     9001 tctgttttaa tgtacaaaat atttagtgga taaaatttta ttaaagattt tatattgttg
     9061 attttcaaac acatatagag caaaaaaagt tctctgctca gcaactttac aatattcatt
     9121 ttttcatcga aaaaaactca aaaaatgctg tttcaaaaga cgaacgtttt ttgaaacaac
     9181 acctatatct taagataaat aactaataac aaga
//
