LOCUS       gnlProkkaMCMBGIFA_120  14743 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCMBGIFA_120.
ACCESSION   gnlProkkaMCMBGIFA_120
VERSION     gnlProkkaMCMBGIFA_120
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:31:53
            Original ID  :: gnl|Prokka|MCMBGIFA_120
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14743
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14743
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7364:7712]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7365..7712
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14743
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14743
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(3..272)
                     /locus_tag="ctg120_1"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRT"
     CDS             complement(306..842)
                     /locus_tag="ctg120_2"
                     /transl_table=11
                     /translation="MDTIQIKDKQFTVSIKEQDIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGVTSTGVIKEVIGLNEDIAGRTVVIVEDI
                     VDTGLTMQRLLDTLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(884..2428)
                     /locus_tag="ctg120_3"
                     /transl_table=11
                     /translation="MSSLKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASSLNNTD
                     LAHWLMYGGLGFMILGNGCFKPTVSSLVGQLYEPGDKRLDAAYTIFYMGVNVGSFAAPL
                     ICGFLGDTGNPQDFKWGFLASGIMTLFTVVLFETQKNKYLFSPSGEPIGIVPDARREKK
                     EDKAEHISHPKMDKRTKVRNIIIITALTVVLIAFFSYAFSDDWISVGIFTACIVFPVLI
                     LLDGSLTKVERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTDRSIFGWEMPASW
                     FQSFNPLFVVILAYIMPGIWGFLNKRNMEPASPTKQAIGLLLLSLGYLFICFGVKDAIP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEDGKVKSILGYQIATMYDFFMLFVIMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(2621..2845)
                     /locus_tag="ctg120_4"
                     /transl_table=11
                     /translation="MMEKKRIGSNAGKVWRILNEKGEQSMFTLCHELGLTFEDVAIAIG
                     WLARENKILLRKKEGMLYASIENVEFTFG"
     CDS             3118..3951
                     /locus_tag="ctg120_5"
                     /transl_table=11
                     /translation="MTTKKLTGILSLFLCIICLVSCNDNDDNFSPITLEYEDPQIKFDN
                     ESRSYTLTPFSKETTPLFIKGGDGTYKVTNENEKVVQVNYHNGSLTLKAKEIGRASIKI
                     EDSSNNMYILSVVVKYRTLTHKAFTAKVIVKGDELTSEEHTELMNKVGNSYPINKYVFT
                     FMNAEDSKGTVDLYYSDNNMKTGNFEKEHIVLDEENAIPIKGEYKLSEYYRITIKEDNG
                     KVIDTFYITKNFLPLLNTRMNAHPLIQYCFVRDLTAQYKQDYLALENAYLIQIAE"
     CDS             4417..5928
                     /locus_tag="ctg120_6"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIEHEPIASIDLMERAAQALTKAITNRWNP
                     ETPVTIFAGPGNNGGDALAIARMMAEKGYKIEVYLFNTKGELSPDCQTNKELVEMMEEV
                     TFHEISTQFVPPTLTPEHLVIDGLFGSGLNKPLSGGFAAVVKYINASPAMVVSIDIPSG
                     LMGEENTFNVKSNIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEEGIEETET
                     NYEMLEIEEIRSLIKPRQQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPLCNNDILQTSAPEAMVETDVSETCFAVPTDTDDYQAVGIGPGLGRNEETEAALIEQ
                     LEHCQTPTVLDADALNILANHRHTLTHLPKGSILTPHPKELERLVGKCQDSYERLMKAC
                     ELAHTAKVHIILKGAYSAIITPEGKCYFNQTGNPGMATGGSGDVLTGVILALLAQGYPA
                     EDAAKIGTYIHGLAGDIAQKKQGMIGLIASDIVTCLPTAWRLVSE"
     CDS             6002..7066
                     /locus_tag="ctg120_7"
                     /transl_table=11
                     /translation="MKKLIIATGLLMATSAYAQTEVLTGVTRGKDYGVVYALPKTQIEI
                     EIKANKVNYKPGEFSKYADRYLRLTNVSAEPEEYWELNSVKVKPVGVPNSEATYFVKLK
                     DKTVAPLMELTEEGLIKSINVPYSSNNAKNAANNAVAPQRKANPRDFLTEEILMASSTA
                     KMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNLQEEAMTEMFSGVRNK
                     EEKTFTVRLTPDKEFDNEVAFRFSKKLGIVANNDLAGTPFYISLKDLKTVKIPQEDGKK
                     KKEMEGIAYNVPGQAMVTLTDGKKKLYEGEIPVTQFGIIEYLAPVLFNKNSTIKVYFDP
                     VTGGLLKVDREESK"
     CDS             7088..7375
                     /locus_tag="ctg120_8"
                     /transl_table=11
                     /translation="MGGEGHMLDMIRRLKDGKEASRLRRERRNDKLGRLRRNNDPYLLP
                     DTTPEEMERIIKDSEKKKEKDNSYFVWGTLIIMGVLIGCAVLLWAIFFNG"
     CDS             complement(7365..7712)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg120_9"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 53.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 6.1e-10, bitscore:
                     29.0, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATKEKINLLEVIPCRNEHIKAEQEGETIVLSFPRFKRSWMSRYL
                     LPKGMSKDIHVRLEEHGTAVWNLIDGQRTVREIIEKLADHFQYEAGYESRVSTYLSQLQ
                     KDGFIKWIIIH"
     CDS             complement(7757..9145)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 90.5; E-value: 1.4e-27)"
                     /gene_kind="transport"
                     /locus_tag="ctg120_10"
                     /transl_table=11
                     /translation="MTEQLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AITTTFPEGAMLFGFKMQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGVFHTNIPAPILFCLVMLCVGTIAFFIYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMVIGSVMLIFVHTMFAL
                     PILNIWWFATVIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNSYCKGPVVDGAQTYDYTLPMAIFAMFGVLALIVALMLKVENKKKGYGLEEA
                     NIQK"
     CDS             complement(9436..9831)
                     /locus_tag="ctg120_11"
                     /transl_table=11
                     /translation="MYLLFIILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSVATAYVVPSSSAAKDVLLEQAQKEQQTNPYNMPTGTAAP
                     QTDATAPAESAPATEAPATETPAPVAE"
     CDS             complement(9838..10632)
                     /locus_tag="ctg120_12"
                     /transl_table=11
                     /translation="MTSVNLQQWIQHPETLNRDTLYELRNQLARYPYFQSLRLLYLKNL
                     YILHDINFGAELRKAVLYIADRRKLFHLIEGERFAVESQKKGLPLSEVLKDEPTVDRTL
                     ALIDAFLSTAPEEVTSQTSFDYSMDYTAYLLEETPVADEPAEAMPKLKGHELIDNFIEK
                     SETDPVVYLKPLREEEKAKAASSAETNETGRTDETTETNTIEEEDDSCFTETLAKIYVK
                     QQRYSKALEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(10637..11164)
                     /locus_tag="ctg120_13"
                     /transl_table=11
                     /translation="MNWIKKIARPLILVVLPAVIIACSVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(11151..12392)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 388.8; E-value:
                     6.1e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg120_14"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVQKTDVRIVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFAADFAEKYRMPAIQLTEDAKKI
                     LLAYPWPGNVRQLKNITEQISIIETNREITAAILQTYLPAQNTQRLPALFGTRESKSFE
                     SEREILYSVLFDMRQEVAELKKMVHNMMAERAGQVGQMGQVVATPVVTTTHQPSVPAII
                     HAVQQPSVCPKEDDDDIQDTEEYVEETLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(12516..13610)
                     /locus_tag="ctg120_15"
                     /transl_table=11
                     /translation="MEENKIRIGITQGDINGVGYEVILKTFSDPTMLELCTPIIYGSPK
                     VAAYHRKALDVQANFSIVNTASEAGYNRLSVVNCTDDEVKVEFSKPDPEAGKAALGALE
                     RAIEEYREGLIDVIVTAPINKHTIQSEEFSFPGHTEYIEERLGNGNKSLMILMKNDFRV
                     ALVTTHIPVREIATTITKELIQEKLMIFHRCLKQDFGIGAPRIAVLSLNPHAGDGGLLG
                     MEEQEIIIPAMKEMEEKGIICYGPYAADGFMGSGNYTHFDGILAMYHDQGLAPFKALAM
                     EDGVNYTAGLPVVRTSPAHGTAYDIAGKGLASEDSFRQAIYVAIDVFRNRQREKAARVN
                     PLRKQYYEKRDDSDKLKLDTVDED"
     CDS             complement(13615..14652)
                     /locus_tag="ctg120_16"
                     /transl_table=11
                     /translation="MKKYFFYLSMALVAFVVASCGLKRNHTSSGRPYELLVVVDAGVWD
                     RAAGRALHDVLDSDMPGLPQSEPSFRIMYTSPKDYDSTLKLIRNIVIVDIKDIYTKGTF
                     KYAKDVYASPQMILTIQAPNEEVFEKFVEENKQTIIDFFTRAEMNRQITLLEEKHNNFI
                     SNKVDSLFDCDIWIPSELNNSKTGEDFFWASTNTGSADRNFVMYSYPYTDKDTFTKEYF
                     VHKRDSVMKANIPGYKEGVYMSTDSLLTDVRPINVHNDYTMEARGLWRMKGDFMGGPFV
                     SHTRLDQKNQRIITAEIFVYSPDKMKRNLVRQMEASLYTLKLPQEGQQSQIPLGVTKEA
                     EPTNK"
     CDS             14654..14743
                     /locus_tag="ctg120_17"
                     /transl_table=11
                     /translation="MFDFYINFYYFPPVSQSTAYRMPQKYPLPA"
ORIGIN
        1 attgttcttg ggaaaccgtc gaaaattaca cctttgctgt ctttgaagct atcgaataca
       61 cttgccagaa tatcaatcat caattcatcc ggaatcaact gcccctggtc gatgtaacct
      121 ttagcagttt tgcccagttc cgtgccgttc ttgatttctg cacgcaatac atctcctgtc
      181 gagatgtggt tgattccata cttttctaca atacgttcgc tctgcgttcc ttttcctgaa
      241 cccggagcac cgaaaattac aatgttcaac atctttttaa cctaaaaatt aatttgtatt
      301 tgaatttaat ctactacagt ataaatatcg ggataattgc gtccgaaacc atcataatcc
      361 aatccgtagc caacgataaa atcattcggt atttccatcg ctacatattc tatgttcaga
      421 ttgaccttca gcttttccgg tttcaccagc aaagaggcga tatgaatcgc ttcggggttg
      481 cgtgtgccca gtgtatccag cagacgctgc atcgtcagtc cggtatctac aatatcttct
      541 acgatcacta ccgtacgtcc ggcaatgtct tcattcagcc cgatcacttc tttaattact
      601 ccggtggaag tcaccccctg ataagatgcc aacttcacga atgaaatttc gcacggaatc
      661 gtaatatgct tcagcaagtc ggcggtaaac atgaacgagc cgttcaacac actgaggaag
      721 agcggattct tacctgccaa atcacgattg atttcgttcg ctacgcgaat cacttctttt
      781 tgaatatcct gttccttaat ggaaacagta aattgcttgt cttttatctg tatggtatcc
      841 ataaccggtc attttaaaaa agttgtcgca aaaatacaat tttttattct accccgtgca
      901 tcatcttctg taatttcttc gagagaagga acagaatcag tgaggcaaca ccggacataa
      961 tgacgaacag catgaagaag tcgtacatgg tagcaatctg ataaccaagg attgatttca
     1021 cttttccgtc ttcgggatag agaccgctca gcatacctgc aaatttattt gcggtggcgg
     1081 tagaaagata ccagatcccc atcatcaagg aggcgaaacg taacggactc aacttattaa
     1141 ccatagaaag cccgataggt gacagagcga tttctcccat tgtatgaata aagtaaagcc
     1201 ctgtcagcca gatcatgctc acctttactc ccggaatagc atctttcact ccaaaacaga
     1261 tgaagagata accaagagaa agcagcaaca gaccgattgc ctgtttggta ggggaagccg
     1321 gttccatgtt tcgcttattc agaaagcccc atataccggg cataatatag gcaaggatca
     1381 ctacaaaaag cggattgaat gactggaacc acgaagccgg catctcccag ccgaaaatgc
     1441 tgcggtcagt ctgttcggaa gcgaataatg tcagagaagc tcctgcctgc tcgtaagctg
     1501 cccagaagaa aatgacgaag aaagctacga tatagattac gaaaatacgg ctacgttcta
     1561 ctttggtcaa tgaaccatcc agcagaatga gcactggaaa gacaatacaa gccgtaaaga
     1621 tacccacact aatccagtca tcgctaaagg catagctaaa aaaggctatt aagacaactg
     1681 taagggcagt aatgatgata atattacgta ctttggtacg tttgtccatc ttcggatgtg
     1741 aaatatgttc ggctttatcc tccttttttt cacgtctggc gtcggggacg ataccaatcg
     1801 gttcaccgga aggagagaaa aggtatttat tcttctgagt ttcaaagagg acaacagtga
     1861 acagcgtcat gattccggat gcgaggaatc cccatttaaa gtcctgcgga ttccctgtgt
     1921 ctcccaagaa accgcaaatc aaaggagcag cgaaagaacc tacattaaca cccatataga
     1981 aaatggtgta tgcagcatcc aaccgtttgt ccccgggttc atataattgc ccgacgagcg
     2041 aagaaacggt aggcttaaag caaccgttac ctaaaatcat gaatccgagt ccgccataca
     2101 tcagccagtg ggcaaggtct gtattgttca gtgaagaggc actcataaac atcaggaact
     2161 gaccgactgc catcatcacc gctccccaaa ataccgaacg acggatgccc caatatttat
     2221 cggcaatgta tccgccgatc aacggagtca gatagaccag tccggtgtag ctaccgtaga
     2281 tagaggccgc cgcttcttta tcaaaaagca atgcctgcgt cagaaagagg ataaagatag
     2341 cacgcatacc gtagtaactg aaacgttctg ccgtgctcgt tgcgaaaatt aggtaaaggc
     2401 ctttcgggtg ccctttcaat gaactcatga attatgtgtt tagtagttta tggggtgcaa
     2461 aggtactaaa aagtagatta aatgcctcaa aaaagaagat tcttatggaa tagaaaaata
     2521 caggatggcg tgcaagaagt ctcagttacc caccttatta tgttttcaac agtgtaaata
     2581 atcaagtgga tattctcctt aaatgtgggt cagtccccat ttatccaaag gtaaattcaa
     2641 cattctcaat actggcatag agcattcctt ctttttttct aagcaggatt ttgttttccc
     2701 ttgccagcca accgatagca attgctacat cctcgaacgt caaacctaac tcatggcaca
     2761 aagtgaacat agactgttcg cccttttcat ttaagatgcg ccatactttc ccggcatttg
     2821 agccaattct tttcttttcc atcatgcaaa ctttagaaga ttaaacaatt tatatttata
     2881 atctaaacat tgtgagcaca ggagaataac gtaaagcaca ttactgcact acaaagatat
     2941 catttttttc gaaaaaagca aataatcaag gcattagctg ctattattag ttacattcta
     3001 atcatttatg ccgatctctg ctaaaaaata gcacaaataa agaaacagtt caattctttt
     3061 tcataagttt gcagacgaga actaaactaa tatcgcacat ttaaaacttt aattagcatg
     3121 actaccaaaa aactaacagg aatactttcg ttattccttt gtattatttg cctcgtgagc
     3181 tgtaatgaca atgatgacaa cttttctcca atcactctgg aatatgaaga tcctcaaatt
     3241 aagttcgaca acgagagccg ttcttacaca ctgactccgt tcagcaaaga aacgacacca
     3301 ctcttcatca agggtggaga cggaacttac aaagtgacca atgagaatga gaaagtggta
     3361 caagtaaact accacaacgg aagtttaaca ttgaaggcaa aggaaatagg acgcgcatcc
     3421 atcaagatag aagacagttc gaataatatg tatatactgt ctgtcgttgt aaaatatcgt
     3481 actcttactc ataaggcgtt tacagcaaaa gtcattgtga agggagacga gcttacatct
     3541 gaagaacaca ctgagttaat gaacaaagtg ggcaattcat atccgattaa taaatatgta
     3601 tttactttta tgaatgcgga agacagcaaa ggaacagtag atttgtatta ttcagataat
     3661 aacatgaaaa caggcaactt tgaaaaagaa catatagtgc tggatgaaga aaatgccatt
     3721 cccatcaaag gtgaatacaa attgagtgag tattatcgta taacaatcaa agaagataat
     3781 ggcaaagtta ttgatacttt ctatattacc aagaactttc taccactcct caatacaaga
     3841 atgaatgctc atccgttaat tcagtactgt tttgtcagag atttaaccgc acagtacaaa
     3901 caagattacc ttgcactgga aaatgcatat ctgattcaaa tagcagaatg agaactacac
     3961 tgattttctt ctttagcaga gtgaatagag tatttattat atgagcaaac tccccattag
     4021 atttagcaaa aaacaataag ctattagcta atcaagaata tgcccatagc atatttatca
     4081 caatcacctc ttccaccctt ttcctgaacc tttgatgaat aaggcgattg cgggtgaaag
     4141 aggtgaacca gaggaatata cagtagtaga aacacgcatg ggaaggttaa caaacagcca
     4201 tgaatgttct ccggagagag taaaagtaaa tgagataaca atcattaata tctgacttct
     4261 caactattaa taactgacac atcaactatt aatacctgac aactcaagta ttaatacctg
     4321 aagttccttc ccaaaaagcc gaaaaccaac cggaataaag gattaattca gagtttttgt
     4381 gtaagtttgt gcgtcgaaaa ctaaaagaat atcgcaatga aaatatttcc aagcagcagc
     4441 attaagaagt tagatgccta taccattgaa catgaaccga ttgcatccat agatttaatg
     4501 gaacgtgccg cacaggcact gactaaagcc atcaccaaca gatggaatcc ggaaacacct
     4561 gtcaccatct ttgccggacc gggcaataat ggcggagacg ccctcgccat cgcccgcatg
     4621 atggcggaaa aaggatacaa gatcgaagta tatctcttca acacgaaagg cgaactttcg
     4681 cccgactgcc agaccaacaa agaactggta gagatgatgg aagaagtaac tttccatgaa
     4741 atcagcaccc agttcgtacc tcccacactg acaccggaac atctcgtgat cgacggatta
     4801 ttcggttccg gactcaacaa accattgagc ggaggattcg ctgccgttgt gaaatatatc
     4861 aatgcctctc ccgccatggt agtctccatc gacatccctt ccgggctgat gggagaagaa
     4921 aatacattca atgtaaaaag caatattatc cgtgcggacg tcactttcag cctgcaactt
     4981 cctaaactgg ccttcctctt tgccgaaaat acagaatttg ttggcgaatg ggagttattg
     5041 gacatccagc tgagcgaaga aggaatcgaa gagactgaaa caaactacga aatgctggaa
     5101 atcgaagaaa tccgttcact gatcaaacca cgccaacaat tcgcccataa aggaaacttc
     5161 ggacatgccc tgctgatagc cggctcaaaa ggaatggcag gtgcatcggt actggccgcc
     5221 cgtgcctgtc tgcgatcggg agtaggtctg ctgacggtac acgcgccgtt atgcaacaac
     5281 gatattctgc aaacgtccgc ccccgaagcc atggtagaaa cagatgtcag cgaaacatgc
     5341 tttgccgtac ctaccgatac ggacgattac caagctgtcg gcatcggtcc gggactcggt
     5401 cgcaacgaag aaacggaagc cgccctgata gaacaactgg aacattgtca gactccgacg
     5461 gtactggatg ccgacgcact caatattctg gccaatcacc ggcatacgct cacccatctg
     5521 ccgaaaggtt ccatcctcac ccctcacccg aaagagctgg aacgcctggt cggcaaatgt
     5581 caggactcat acgaacgact gatgaaagcc tgcgaactgg cgcacactgc caaagtacat
     5641 atcattctga agggagctta ttccgccatt atcacccccg aaggcaaatg ttacttcaac
     5701 cagaccggta atcccggtat ggcaacagga ggcagcggag atgtactgac aggagtaatc
     5761 cttgcactcc ttgcgcaagg ctatcccgcc gaagacgccg caaagatcgg tacttacatt
     5821 cacggattgg ccggagacat cgcccagaaa aaacagggca tgatcggatt aatcgcaagt
     5881 gatatcgtga cttgtctgcc gacggcatgg cgacttgtaa gcgaataaaa gttaagaact
     5941 tacggtttat tcaataactt cattaacttt gtttttcaaa atcagctaaa aagaaccgaa
     6001 tatgaaaaag ttaatcatag caacaggact actaatggca acttccgcct atgcgcagac
     6061 cgaagtgctg acaggagtga cgcgaggaaa agactacgga gtagtgtacg ccctccccaa
     6121 aacccagata gaaatagaaa taaaagcaaa caaagtcaac tataagccgg gtgaattcag
     6181 caaatacgcc gaccgctacc tgagactgac caacgtctct gccgaacccg aagaatactg
     6241 ggaactgaac agtgtcaaag tgaaacctgt aggtgtacca aacagcgaag ctacttattt
     6301 cgtcaaactg aaagacaaaa ccgtagctcc tcttatggaa ctgactgaag agggtcttat
     6361 caaatcaatc aatgtcccct acagcagtaa caatgcaaag aatgcagcaa acaatgccgt
     6421 tgctccccaa cgaaaagcca atccccgcga ctttctcaca gaagaaattc tgatggcaag
     6481 ttcaaccgcc aagatggccg aactggtagc aaaggaaatc tataatatcc gcgaaagtaa
     6541 aaacgcatta ttgcgcggac aagcagataa tatgccttcg gacggcgcac agctcaaaat
     6601 catgctcgac aacctgaatc ttcaggaaga agccatgacc gagatgtttt cgggagtccg
     6661 caataaagaa gaaaagacat ttactgtccg cctcactccg gataaggaat tcgacaatga
     6721 ggtagctttc cgcttttcaa agaagctggg tatagttgcc aacaacgatt tggcaggcac
     6781 tccattctac atcagtctga aagacctgaa aacggtgaag attccgcaag aggacgggaa
     6841 aaagaagaaa gagatggaag gcattgctta taacgtaccg ggacaggcaa tggtgacgct
     6901 gacggacggc aaaaagaaat tgtatgaagg agaaatacct gttactcagt tcggtatcat
     6961 agaatacctt gctccggtat tattcaacaa gaactcgacc atcaaagttt actttgatcc
     7021 ggtgaccggt ggactactga aagtagatag agaagaaagc aaataaaacc tctaaaaaaa
     7081 caaaacgatg ggtggcgaag gacatatgct cgacatgata cgtcggctga aagacggcaa
     7141 agaagcctcc cgcttacgcc gtgaacggag aaatgacaag ttagggcgac ttagaagaaa
     7201 caacgaccct tatcttctgc cggatacgac tccggaagag atggaacgca tcatcaagga
     7261 ttcggaaaag aaaaaagaaa aagataacag ctatttcgta tggggaacgc ttatcattat
     7321 gggcgtactg ataggatgtg ctgtcctcct gtgggcaatc ttttttaatg gataattatc
     7381 catttaataa atccgtcttt ctgtaattgg gaaagatagg tagatacacg agactcgtag
     7441 cctgcttcat attgaaagtg gtctgcgagt ttttctataa tctcacgaac cgtccgctgc
     7501 ccgtctatca ggttccatac ggccgtaccg tgttcttcca gacgcacatg aatatctttg
     7561 gacattcctt tcggcaataa ataacgactc atccacgaac gtttaaaacg agggaaggag
     7621 agcacaatag tctccccttc ctgttcagct ttaatatgtt cgttacgaca aggtatcacc
     7681 tccaggaggt ttattttctc tttcgtagcc atatcttttc tcttttatat cttttcagat
     7741 agaatatata ctgtgattat ttctgaatat ttgcttcttc cagtccgtag cctttcttct
     7801 tgttttccac tttcagcatc aaggcaacaa tcagggcaag tacaccgaac atagcaaaaa
     7861 tagccatcgg caaggtataa tcataagtct gtgcaccatc tacaaccgga cctttgcaat
     7921 aagagttcaa cacccatccg atcagcaaag gcacgcccat caatccccag ttctgtaccc
     7981 aaaagatcaa cgcataagcc gttcccaact gtttctccgg aataatcttc ggaaccgaag
     8041 gccacattgc cgaaggaacc aatgagaaag caaatcccag aataatcatg atcaccgttg
     8101 caaaccacca tatattcaga ataggaagag cgaacatcgt gtgtacgaaa atcagcatca
     8161 ccgacccgat caccatcagc gtggctccct taccgatacg gtcatataat gaaccgaaca
     8221 atggtgtcag gatgatcgcg ccaatcggca gcaatccggg aatcgttccc gcaagtttcg
     8281 gatcaacatt gtacttctgt accatcaaat cggccgcata cttgatgaag gggaatacag
     8341 ccgaatagaa caatacgcac agtaatgcga tcagccagaa tcctttgttg gtaatgatat
     8401 agacaatgtc tttcatgcgg aaaggttctt ccggttccag tccttccgca tccagtgaag
     8461 catccagttt cttatcgtag aaagtataga tgaagaatgc gatggtacct acgcacaaca
     8521 tgacgagaca gaacagaatc ggagcgggaa tattggtatg gaatacgccg ctctcatccg
     8581 tagacccgaa gaagtctgcc aaaggaacgg taagcaccat ggccaaagtt gttccaatac
     8641 gcgcggtcgc catttccagt cccatagcga gagccatctc tttgccttta aaccacttca
     8701 cgataatctt cgaaacggtg atacccgcaa tttcgactcc tacaccgaaa atagcataac
     8761 ccaatgcagc caatgtgact tgcatcttga atccgaaaag catcgcacct tccgggaaag
     8821 tagtagtaat agcataatat ttcaatccac aaccgaacac catcaataaa caggcaccca
     8881 ttccggtgaa gcgtactccc atcttatcca gaatgatacc accaaagatg agcatcagca
     8941 ggaatacatt aaaccagcca taagcactgg tgaaaaaacc gtaatctaaa ctgtcccaga
     9001 gaagttcttt ttcaagcatg ggtttcagag gagacataac gtctgtgagg aagtagccgc
     9061 acaacatggt aaaagcgact aatgctagaa cactccaacg cagcactgcg gagtcattca
     9121 gcttttgttt caattgttct gtcattgtaa tatttaaaag gagttaataa tctcgtaacg
     9181 ggcaacaaag ttaactaatt atcatttgtt ttactaaaaa aggagaacat tttataagaa
     9241 aaaggacatc tgaccggata ttcctgtatg aagaagagca gaccgggccc aataataaag
     9301 acagacgcga actacacgta ttacacgatt ctattagaat ctcttgtaat tcgcgtaatt
     9361 cgcgcctata atgaagagaa cgggtcaaaa agcccgttca ctcaataagt ttaaaccgaa
     9421 tatcctgtca ctgaattatt ctgctacagg agcaggagtt tcagtagccg gagcttccgt
     9481 tgctggtgca gactctgcag gagcagtagc atctgtctga ggagcagcag taccggtagg
     9541 catattatac gggttggttt gttgttcttt ctgtgcttgt tccaacaata catctttagc
     9601 tgcagaagaa gaaggaacaa cgtaagcagt agcaacgctc atcacaacca tgaagatagc
     9661 cagaccccaa gttgcttttt ccagaaaatc tgtagtcttg cgcacgccca tgatagcgtt
     9721 tgatgaagaa aaaccagaag caagtccgcc tccttttgaa ttctgaatca gcacgatgaa
     9781 gcacatcagc aaggctgcaa tcaccattaa gataatgaat aataagtaca tttttagtta
     9841 ttttgaatta gcgttaataa tcaatttctc caaaaatctg atttggtctg caaagtaagc
     9901 attttttttt ggatatttca agcttaattt tttaattatt tcaagagctt tcgaatatcg
     9961 ttgctgtttt acgtagattt tggccaaagt ttctgtgaaa cagctgtcat cttcctcttc
    10021 tatggtgttg gtttcagttg tttcgtctgt tctgcccgtt tcgtttgttt cagcggaaga
    10081 agctgccttt gctttctctt cttccctcaa aggtttcagg tatacgactg gatcagtctc
    10141 gcttttttcg ataaagttgt caatcagctc gtgtcctttc agcttgggca ttgcctctgc
    10201 cggctcgtcg gcgacaggtg tctcttcgag aaggtatgcc gtatagtcca tggagtaatc
    10261 aaagcttgtc tgactggtta cttcttcggg agccgtcgaa aggaaagcat cgatcagagc
    10321 cagtgtccgg tcgacggtag gctcatcttt caatacttca gagagaggca accctttctt
    10381 ctgggattcg acagcgaagc gttcgccttc gatcagatga aacagtttcc gtcggtcggc
    10441 aatatacaga acggctttcc gcagttccgc accgaaatta atgtcgtgga gaatatacag
    10501 gttcttgaga tacaacaacc ggagcgactg aaaatacgga tacctcgcga gctggttgcg
    10561 cagttcgtac aaagtatccc tattcagcgt ctcgggatgc tgaatccatt gttgcaagtt
    10621 aacagaagtc attaaattac cagtttgcta cagttgcatt aaatatttgg tcggttatct
    10681 ctttactcat ttccgctatt aatccatcct gtacggccgt cagcagctgg ctggaatcat
    10741 aggtacggaa agctgagaat tgttgttcga agtcttcggc gtgatttgtg ttgttgacaa
    10801 agcgtacatt gaccgtgatg gtcagcttcg tttccgaaga gtaaccatcg gcagacactg
    10861 cctggttata ctggttgtag cccgtaattt caccgtcaat ctgcagatcc gcattctggt
    10921 tcggtttcag cagttgcaga cgggtctgtc tgatgaagat atctttcagg tcttcattga
    10981 acttggtagc cagcggagca tacacatact ccgacttaat cgggaaatca gcaatcgaaa
    11041 tagtcttcac cttatcgtaa ttgatagagg agccattaaa cttataggac acactacagg
    11101 cgatgatgac tgccggtaaa acaaccaata tcagcggtcg tgctattttc ttaatccaat
    11161 tcatattctt ttatttttct gtaaagggta cgctcggaga tattcagatc cttcgccgca
    11221 cttttccgct taccatgatg cctctcaagc gctttacgta tcatttcttt ttccacttca
    11281 tcgagcgaaa gggtttcttc tacatattct tccgtgtcct gaatatcgtc atcgtcttct
    11341 ttgggacaaa cagacggttg ctgcacagca tggataatgg ccggcacgga aggttggtgc
    11401 gtcgttgtca ctaccggagt agctactacc tgtcccatct gtccgacttg tcccgcacgt
    11461 tcagccatca tattgtgcac catcttcttc agttccgcca cttcctgacg catatcgaac
    11521 aagacagaat atagtatttc gcgttcgctc tcaaagctct tgctctcgcg tgtgccgaac
    11581 agtgccggaa ggcgttgggt attctgtgcc ggaagatagg tctgcagaat cgcagccgtt
    11641 atctcacggt ttgtttctat aatcgaaatc tgctctgtga tgttcttcaa ctgccggacg
    11701 tttcccggcc acggataagc aagcaatatc ttcttggcat cttccgtcag ctggatagcc
    11761 ggcatccggt acttttcggc aaagtctgcg gcaaacttac ggaacaacaa cagcacatca
    11821 tctccacgct cacgcaaagg tggtatctga ataggcaccg tgttcaaccg ataatacaaa
    11881 tcttcccgga agcgtccttc ggcaatggct tgtgtcaggt tcacgttggt agctgccaca
    11941 atacgtacat ccgtcttttg cactttggat gaacctacct tgataaattc accgctttca
    12001 agtacacgga gcagacgcgc ctgtgtaggc aacggcaact ctcccacttc atcaaggaag
    12061 atggttccac cgtcagcttc tccaaaatat cctttccgct caccaatagc accggtaaat
    12121 gctcctttct cgtgtccgaa cagttcggaa tcgatcgtac cttccggtat ggcaccacag
    12181 ttgacagcaa tatactgccc atgctttctc cggctatatt gatgaatgat ctgtggaaaa
    12241 ctttcttttc cgacaccact ttctccggta atcagcacag acaaatcggt aggcgctacc
    12301 tgaatggcaa catctatggc acgtgataag gcctcggtat tgccaataat accgaaacgc
    12361 tgtttcactt gttgtatctc tgctttggtc atctatctta atattaagta ataggtaata
    12421 agtattaagt aataagtatt aagtattacc atcactatca tctcgcttct atccgcatgg
    12481 ctaatactta atacttatta cttaatacct attacttaat cttcgtctac tgtatccagt
    12541 tttagtttat cactatcgtc ccgtttctcg taatactgct tccgcaacgg gtttacccgt
    12601 gctgctttct cgcgctggcg gttgcggaat acatcaattg ctacataaat agcctggcgg
    12661 aaagagtctt cgctggccag tcctttaccg gcgatgtcat aggctgttcc atgagccgga
    12721 gaggtacgta caaccggcag tccggcggta tagttcacac cgtcttccat agccagggct
    12781 ttgaacggag ccagtccctg atcatgatac atagcaagga ttccgtcaaa gtgggtataa
    12841 ttgcccgaac ccataaaacc gtccgcagca taaggaccgt aacagatgat ccctttctct
    12901 tccatttctt tcatggcagg gataatgatt tcctgttctt ccatacccag cagtccgccg
    12961 tctcctgcat gaggattcag tgaaagcact gcaatacggg gcgcaccgat accgaaatcc
    13021 tgtttcaggc aacgatggaa aatcatcagc ttttcctgaa tcagttcctt ggtgattgtt
    13081 gtagcaatct cccttaccgg aatatgcgtc gttactaaag ccacacgaaa atcgtttttc
    13141 atcaggatca tcagtgactt gtttccattg cccagacgtt cttcaatata ctccgtatgc
    13201 ccggggaaag agaactcttc cgactgaatg gtatgtttgt tgatcggagc tgtcacaatg
    13261 acgtcgatca gcccctcacg atactcttct atggcacgtt ctaaagcacc caatgcagcc
    13321 ttacctgctt cgggatcggg tttggagaat tccactttca cttcgtcatc cgtacagttc
    13381 actacactca gacggttgta tccggcttcg gaagctgtgt tgacaatgct gaaattagcc
    13441 tgtacatcca gtgctttacg atggtaagcc gctactttag gtgaaccgta gataatcgga
    13501 gtacatagct caagcatggt agggtctgag aatgtcttca agatcacttc ataacctacc
    13561 ccgttgatat ctccttgggt aatgccgatt cttattttgt tttcttccat gtttttattt
    13621 attagttggt tccgcttctt tggttacccc cagtggaatc tggctctgct gaccttcttg
    13681 cggaagtttc agcgtataaa gagatgcttc catctggcga accagattgc gtttcatttt
    13741 atcgggtgaa tatacaaata tttctgctgt aataatacgt tggttcttct gatccagacg
    13801 agtatgggaa acgaacggcc cacccatgaa gtcacccttc atgcgccaca atccacgagc
    13861 ttccatcgtg tagtcattgt gcacgttgat cggacgaaca tcggtcagta acgagtctgt
    13921 cgacatatat acgccttctt tatatccggg gatattggct ttcatcacgg aatcgcgctt
    13981 atgaacaaag tattctttgg tgaatgtatc cttgtcagta taaggataag aatacatcac
    14041 gaaattgcga tccgcgctgc ctgtattggt agatgcccaa aagaagtcct ctcctgtctt
    14101 ggagttattc agttcggaag gtatccagat atcgcagtca aacagactat ctaccttatt
    14161 tgagataaag ttgttgtgct tttcctccag caaagtaatc tgacggttca tttcagcgcg
    14221 agtgaagaag tcgataatcg tctgcttgtt ttcttcgaca aacttctcaa acacttcttc
    14281 gttcggagcc tgaatggtca gtatcatctg tggagaagca taaacgtctt tcgcatactt
    14341 gaaagtacct ttggtataaa tatcttttat atctactatc acaatattac ggatcaactt
    14401 cagcgtagaa tcatagtcct tcggtgaagt atacataatc cggaaagaag gttccgactg
    14461 gggcagtccc ggcatgtcag aatcaagcac atcatgcaag gcccttccgg cggcacggtc
    14521 ccacactccc gcatctacta caaccaacag ttcatacgga cgaccgctag aggtatgatt
    14581 cctctttaat ccacaagaag caactacgaa ggctaccaga gccatgctta aataaaaaaa
    14641 gtactttttc atgatgttcg atttttatat taacttttat tattttcctc ctgtttcgca
    14701 gtcgacagca taccgcatgc cgcaaaaata tcctctcccc gcg
//
