LOCUS       gnlProkkaJBGAHFHO_88   11079 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JBGAHFHO_88.
ACCESSION   gnlProkkaJBGAHFHO_88
VERSION     gnlProkkaJBGAHFHO_88
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:41:23
            Original ID  :: gnl|Prokka|JBGAHFHO_88
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11079
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11079
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4478:6250]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4479..6250
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..11079
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11079
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             134..880
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MYQFFIQPDSIKEEEIWIADPQDVNHIRNVLRMKKGEKVSLCCEA
                     KGKEYICSIEEIESDIVKAAIIDINGESRELPVKITLFQGLPKSDKMELIIQKAVELGV
                     AEIVPMATKRAVVKLDAKKAAKKVQRWNEIAKSAAKQSKRGLIPEVKPVMSFKEAVEYG
                     KSMDMLLIPYEDAKGIAHSREVVETVKDKKSLGIYIGPEGGFPEEEVSLAMKAGAEPVT
                     LGHRILRTETAGMTLLSILMFMLEED"
     CDS             967..2076
                     /locus_tag="ctg88_2"
                     /transl_table=11
                     /translation="MAGSSFGTLFRMTTWGETHGKGVGVVVDGCPAGLSLCEEDIQKYL
                     NRRKPGQSKYTTKRKEDDKVEILSGVFEGKTTGTPISMAVFNKDQHSKDYSAIKDIYRP
                     GHADYTFDKKYGFRDYRGGGRSSGRETTARVAAGAVAAKVLKELGIEVFAYTKAIGPVQ
                     IDENRFSKEERDKNALYMPDAQAAAQAEEYLQEKMKELDSCGGIVECVITGMPVGVGEP
                     VFDKLSANLGKAILSIGAVKGFEIGDGFAAAASAGSENNDDFYNDNGTVKKKTNHAGGV
                     LGGMSDGSVITFRAAFKPTPSIAQPQQTVNRDGKDTEIVIHGRHDPIIVPRAVVVVETM
                     AAVTVLDLLLQNMGSRLDSVKNFYENEKK"
     CDS             2145..3287
                     /locus_tag="ctg88_3"
                     /transl_table=11
                     /translation="MYKLLTKDGMAKRGEFETVHGTIQTPVFMNVGTVGAIKGAVSTDD
                     LRTIGTQVELSNTYHLHVRTGDKLIKQFGGLHKFMGWDKPILTDSGGFQVFSLSGLRKI
                     KEEGVYFQSHIDGHHIFMGPEESMQIQSNLGSTIAMAFDECPSSRADRTYIQNSVDRTT
                     RWLERCKKKMQELNSLPDTVNPHQMLFGINQGGVFADIRIEHAKRISELDLDGYAVGGL
                     AVGETHDEMYYILDEVVPYLPENKPTYLMGVGTPANIIEAVDRGIDFFDCVYPSRNGRH
                     GHVYTHHGKLNLFNKKFELDPRPIEEGCQCPACRTYSRAYIRHLLKAKEMLGMRLCVLH
                     NLYFYNHLMEEIRGAIDEHRYKEFKKTTLEGFLTPEEEYR"
     CDS             3321..3641
                     /locus_tag="ctg88_4"
                     /transl_table=11
                     /translation="MLLAQSASASSSITMIIAYVILFGAIIYFMTIRPQKKQQKAADEM
                     HAGMQAGDSVLTTSGFYGVIIDIMDDTVIVEFGNNRNCRIPMQKDAIAAVEKPNLTKTE
                     EE"
     CDS             3999..4379
                     /locus_tag="ctg88_5"
                     /transl_table=11
                     /translation="MDGISYKKWMERAAGLFLSALIAVLLTMLFLAVFAFAMLKGNLSA
                     SVEKIGLIVMSVMACFVGGFLCGKKNIKKRYLWGLGVGVLYCLFFGVIRVGMGQAFVTD
                     TTAFFTMMLYCAAGGMLGGMLS"
     CDS             4479..4625
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_6"
                     /sec_met_domain="TIGR03973 (E-value: 4.6e-23, bitscore:
                     70.6, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 2.3e-22, bitscore: 68.4,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVKTLTGNKTYGTTMCKGGCGECQTSCQSACKTSCTVGNQTCE
                     SNK"
     CDS             4886..6250
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_7"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.3e-33,
                     bitscore: 104.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3e-16, bitscore: 49.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.6e-14, bitscore: 43.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.4e-20, bitscore:
                     63.3, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVMDVCSGAIHVVDDVTYDVIALYEEKSLEEIEN
                     ELSYSKEDIEEAYKEVTSLKEEGLLFTEDIYEDYIKEVKSRKTVVKALCLHIAHDCNLA
                     CRYCFAEEGEYKGHRELMSAKVGKAALDFLVANSGNRHNLEVDFFGGEPTMNFGVVKEV
                     VEYGRSLEEKHNKHFRFTLTTNGVLLNDEIMEFANKEMDNVVLSVDGRKEIHDYMRPTR
                     NGKPSYDLIMPKFIRFAESRHQQKYYVRGTFTNRNLDFSKDVLHLADLGFEQISMEPVV
                     GQPEEPYAIQEKDLPQIFDEYDRLAKEMIKREKAGKGFNFFHFMIDLTGGPCVAKRLSG
                     CGSGTEYLAVTPWGDLYPCHQFVGEEKFLLGNVFDGIKRTDICDEFRSCNVYTKKKCKD
                     CFARFYCSGGCPANSYNFHGTIDDSYDLSCDMERKRVECAIMIKAALADTEGEEE"
     CDS             6251..8026
                     /locus_tag="ctg88_8"
                     /transl_table=11
                     /translation="MEKWFIASKRADFNKIGEIFHISPVTARLMRNRSLTTVGEMQRYL
                     YGSLSDLYDSHLLKDADKGAEIIREKIETGKKIRIISDYDVDGVSSNYILYQGLKRCGA
                     DVDYKIPDRVEDGYGINEHLIEKAAEDEIDTIITCDNGIAAAEQIAYGNSLGLTLIVTD
                     HHDIPFQRQEDGSISYNLPSAAAVINPKQKDCPYPFENICGAVVVYKFIQVLYDLFGID
                     RRESEAFLEIAAMATVCDVMPLCDENRIIVKEGLRRIQHTNITGLQALIEANHLEEKKI
                     SSYHFGFILGPCINASGRLTSAKDALELLLCEDKELCRQKAEALTQLNAERKEMTANGV
                     KAAKEYLESTGHANDKVLVVYLPNCHESIAGIIAGRMKEHYHKPVFVITRTKEGLKGSG
                     RSIEAYHMYKEMNKIKECFDKFGGHPMAAGFSMQEDRLEEFREKLNANATLTEDDFAEK
                     VHIDVALPISYLSESLINEFELLEPFGNENTKPLFAQKDLYIKGMRVLGTTGRCLKLFL
                     SDANGTSIDAMYFGESDGFLEELISFCGKEEAQRIQKGLSHHIWMDVTYYPQVNEWRGQ
                     KNIQIVIQNYRFKNL"
     CDS             8197..9042
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1179:hydrolase (Score: 176.9; E-value: 1e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_9"
                     /transl_table=11
                     /translation="MEQEKKQPDVRLIGLDLDGTTLTSDKVLTPHTKEVLEKCLAEGIQ
                     VLPATGRVKSGIPEYLTQIEGMRYVILSNGASVLDLKEDKVLYQNCIPWERALELFDVL
                     ETYDTFYDIYALGAGWCEARFYDNVENYGIEKHIEKLVRTSRNRIDDLREWMKENKAPV
                     EKINMFFAKEEDRQRAFRELGQIEDLAVTCSLGNNLEINGATCNKGDAMFNLGKILDIP
                     AESIMACGDGNNDFEMVKMAGVGVAMKNGEESLKEVADFVTKTNDEEGVAYAIEHFCNV
                     "
     CDS             9177..9701
                     /locus_tag="ctg88_10"
                     /transl_table=11
                     /translation="MKKLEDYVINIPDFPKPGIIFRDITSILRDPEGLKLSVHELMHCL
                     EGTEFDVVVGAESRGFLFGMPLAYNKSKGFVPVRKKGKLPRETVSKEYALEYGTAEIEI
                     HKEDIRPGQRIVFVDDLLATGGTAKAAIDLIEELGGVVVKVLFVMELEGLHGRDVLKGY
                     DVDSVITYPGK"
     CDS             9899..10768
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="MEHLNLLQRIEKKSSEFSKGQRRLAQYITENYDIAAYITASKLGK
                     EAGVSESTVVRFAYQLDYEGYPELQKAIQVIVKTNSNSIQRMSLSSKRYQEKGVLKSIL
                     YTDSERLRDTIQSGVDEEEFNRSVMLINDARRLYILGARSAAYLAGLMGYYFKMMFDNV
                     IIVDANSTSETLEQIYDISDKDVMMGITFPRYSKRTICALQYAKNHGAKTIALTDNMQS
                     PIVEYADCKLIAKSDVMTIVDSLVCPLSVVNAMVTAIALLRKDDVEKRLMALEELWNEY
                     DVYNRSLL"
     CDS             10768..11079
                     /locus_tag="ctg88_12"
                     /transl_table=11
                     /translation="MNKVIIVGGGAAGMMAAISASKEGKKACILEKNEKLGKKLFITGK
                     GRCNITNACPADEFLTHVVTNPRFLYSTFSQFNNEDMMDYLEEIGLPIKTERGQRVFPQ
                     "
ORIGIN
        1 tatgccttat tgggggcaat ggcttcgtct gtagtttgtc taatgaatta aatagaaaat
       61 tgacatattt tttgaaagcg gttatgatat attatgtctg ccttataggg caaagaatga
      121 agtggaggag tttatgtatc agttttttat acagcctgat agtattaaag aagaggagat
      181 ttggattgca gacccgcagg atgtaaatca cattcgtaat gttctccgta tgaaaaaggg
      241 agaaaaagtt tctctttgtt gcgaagcaaa gggaaaggag tacatttgta gtatagaaga
      301 gatagaatca gatatcgtca aggcggcaat tattgatatt aacggagagt cgagagaact
      361 gccggtaaag attacgcttt ttcagggact tccaaagagt gacaagatgg aacttatcat
      421 tcaaaaagcg gtagaactcg gggtggcaga gattgtgccg atggcaacaa aaagagcggt
      481 tgtaaagctt gatgcgaaga aggcagcaaa gaaagtacag cgatggaatg agattgcaaa
      541 aagtgcggct aagcagtcaa agagaggtct gattccagaa gtaaagcccg taatgtcttt
      601 taaagaagct gtggaatatg gaaagagtat ggatatgcta ctcattccgt atgaggatgc
      661 caagggaatc gcacattcca gagaagtggt agaaacagta aaagataaaa agagtctggg
      721 aatttatatc ggaccggaag gtggttttcc ggaagaagag gtttctcttg cgatgaaagc
      781 aggagcagaa ccggttacac ttgggcaccg cattttgcgg acggaaacgg cgggaatgac
      841 attactttct atattaatgt ttatgttaga agaagattga tttggtgtag atagtagaaa
      901 tttaattgat gaaaagtcaa acagaggata ctctgtttga cgatagaatt ttaacaggag
      961 gacaaaatgg caggttcatc atttgggaca ttgtttcgta tgacaacatg gggagaaaca
     1021 cacggaaaag gtgtgggtgt tgtagtggac ggttgtccgg caggcctttc tctttgtgag
     1081 gaggatatac agaagtattt gaatagaaga aagccgggac agtcaaagta cacaacaaag
     1141 cgaaaagaag atgataaggt ggagatttta tcgggagttt ttgagggaaa gacaacagga
     1201 actccaattt ctatggcggt atttaataaa gaccagcatt caaaagatta ctctgcaatc
     1261 aaggatattt accgtccggg ccatgcagat tatacatttg ataagaagta tggtttccgt
     1321 gattatcgcg gtggcggccg ttcttcagga agagagacaa cagcaagagt agcagcaggt
     1381 gcagtagcag caaaagtatt aaaagaactt ggcattgaag tatttgctta tacaaaagca
     1441 attgggccag ttcaaattga tgaaaataga ttttcaaaag aagaacgaga taagaacgca
     1501 ttatatatgc cggatgcaca ggcagcagca caggcggaag agtatcttca ggagaaaatg
     1561 aaagagttag attcctgtgg tggcattgtg gaatgtgtaa ttacaggaat gcccgtcggt
     1621 gttggtgagc cggtatttga taaattaagt gcgaatcttg gaaaagcaat tttatctatc
     1681 ggagcagtaa aaggcttcga aatcggagat ggatttgcgg cggcagcaag tgctggttct
     1741 gagaataatg atgattttta taatgataat ggtacggtga aaaagaaaac gaatcatgca
     1801 ggtggtgtgc ttggtggaat gagcgatggt tcagtaatta catttcgtgc agcatttaag
     1861 ccaactccat cgattgcaca gccacagcag acagtaaata gagatggcaa agatacagaa
     1921 attgtaattc acggaagaca tgacccgatt attgtgccaa gagcagtcgt tgttgtagag
     1981 acaatggcag cggtaactgt tcttgatctg ctgcttcaga atatggggag ccgcttagat
     2041 agcgtaaaaa acttctacga aaatgagaaa aaataaggat agaggttgta catttgcttt
     2101 gtttatgata aaattaaatt tatgtgtaaa gttaaggaga gtatatgtat aagttattaa
     2161 cgaaagatgg catggccaaa cgaggagagt ttgagacagt ccatggtacg atacagactc
     2221 ctgtttttat gaatgtagga acagtaggag caatcaaagg tgctgtaagc acggatgacc
     2281 ttcgtacaat cggaacgcag gtggagctgt ctaataccta tcatcttcat gtaagaacag
     2341 gtgataaact aatcaaacag tttggcgggc ttcataaatt tatgggatgg gataaaccaa
     2401 tccttaccga ttctggcgga tttcaggtgt tttctctgtc aggtcttcga aagataaagg
     2461 aagaaggcgt atatttccag tcacatattg atggacatca tatttttatg ggaccggaag
     2521 aaagtatgca gattcagtct aatcttggtt ctacgattgc gatggcattt gatgaatgtc
     2581 cttcaagtcg ggcagacaga acctacattc agaattctgt tgacagaaca acaagatggt
     2641 tagaacgctg taaaaaaaag atgcaggaat taaacagcct gccagatacc gtaaatccac
     2701 accagatgtt atttggtatt aatcagggtg gtgtttttgc ggatatccgt atcgagcacg
     2761 ctaaaagaat cagtgagctt gatttggatg gttatgcagt tggcggactt gcagtaggag
     2821 agacacatga tgagatgtac tatatccttg atgaagttgt tccgtatctg ccggaaaata
     2881 aaccaactta ccttatgggt gtaggaaccc cagcaaatat tattgaggca gttgacagag
     2941 gaatcgactt ctttgactgt gtatatcctt ccagaaatgg aagacacgga catgtgtata
     3001 cgcatcatgg aaagttaaat ctttttaata agaagtttga attagacccc cgcccaatcg
     3061 aggaaggatg ccagtgtccg gcatgtcgga catacagcag agcctatatc agacacctgc
     3121 tcaaggcaaa agagatgctt ggaatgcgtc tttgtgttct tcataacctg tatttctata
     3181 atcatttaat ggaagaaata cgtggagcaa ttgatgaaca ccgctacaaa gagttcaaaa
     3241 aaaccacatt agaaggtttt ttgacaccgg aagaagaata ccggtaatat attatataga
     3301 agaataacgg aggtaaggac atgttattag cacagagtgc gagcgcaagc tcatctatta
     3361 caatgatcat tgcatatgtc attctttttg gagcgattat ctactttatg acaatccgtc
     3421 cacagaagaa gcagcagaaa gcagcagacg agatgcatgc aggaatgcag gctggagaca
     3481 gcgtattgac tacaagcgga ttctatggcg taatcatcga catcatggat gacactgtaa
     3541 tcgtagaatt tggtaacaac cgtaactgca gaatcccaat gcagaaagat gctattgcag
     3601 cagtggagaa gccaaatctt acaaagacag aagaagagta gtttcggtta gcgggacaga
     3661 cgaaaaatga aaaagcagat atcctatatt tgtgactcta tcactgcggg ttgaatgttc
     3721 gcctccgggt tcacattcaa tcctcgctct aaggccacaa atataggata tctgcttttt
     3781 gctaaattga aagtactctc cagtttaaca aagacagaaa ttaagagacc gccaatatat
     3841 aaaaaatgcg ccttagagca agctcttaat gcggacgagc attaagagcg cagtgatacg
     3901 aagcattttt tatatattgg cggtctctta atttcgtctc ccctgttcta aacagagccc
     3961 ccttttcata ggctataaaa aagcctttgg tgcagcctat ggatggaatt tcgtataaaa
     4021 aatggatgga gcgtgcagca ggcctgtttc tttctgcatt aattgcagta ttactcacaa
     4081 tgctattttt agcagtgttt gcatttgcca tgttgaaagg taatctttcc gcttccgtag
     4141 aaaaaattgg tttaattgtt atgagtgtga tggcttgttt tgtcggggga tttttgtgtg
     4201 ggaaaaagaa tataaaaaaa cggtatttat gggggcttgg cgtaggtgtt ttatattgct
     4261 tgttttttgg agtaatacgc gtcgggatgg ggcaggcatt tgtgacagat acgacagcat
     4321 tttttacaat gatgctttat tgtgcggcag gaggaatgct tggaggaatg ttaagctaaa
     4381 aagttctttt cttacgggag ggtttgtgtt ataataacct acaaagtgtc atcttagatg
     4441 ctttacatac tagatcatga agtgaggagg cgttattaat gaaacgtgta aagacactga
     4501 ccggaaacaa aacttacggt actacaatgt gtaaaggtgg atgcggcgag tgccagacat
     4561 cctgccagtc tgcctgcaag acatcttgta cagtaggtaa ccagacttgc gagagtaata
     4621 aataattaga gagcacaaca ggaagaatgc ttcctgatat atgcttgaag tagggtgaac
     4681 tgtctttttt gtcagttcac cttatctctt gtatggaaaa atatgtttgc agagattact
     4741 ttattgtaag ttgaaaatat tgtatacagg aatgttctgt attatatatc tattttaaag
     4801 ttagcaggac atatcttcaa attaaaaata tattttagaa aattaagtat aaaaactata
     4861 aaagaaatag aaagggatat ttaacgtgat tcaccagtat aaaaataatg gatataatat
     4921 tgtcatggat gtgtgcagtg gtgccattca tgttgttgat gatgtgactt atgatgtcat
     4981 tgctttatat gaagaaaaaa gcttggaaga aatagaaaat gaactttctt acagcaagga
     5041 agatattgag gaagcatata aagaggtaac ttctttaaaa gaagagggac ttttatttac
     5101 agaagatatt tacgaagatt atattaaaga ggtaaagagc agaaagacag tagtaaaggc
     5161 actttgcctg catattgcac atgattgtaa tcttgcctgc cgctactgtt ttgcagaaga
     5221 aggagagtat aaaggacacc gtgaacttat gagtgcaaag gttggaaagg ctgcccttga
     5281 tttccttgta gccaattctg gaaaccgtca taatcttgaa gttgacttct ttggcggtga
     5341 gccaacaatg aacttcggtg ttgtaaagga agttgtagaa tatggacgtt ctcttgaaga
     5401 aaaacataac aaacatttcc gtttcacttt gacaaccaat ggtgtgctgt taaatgacga
     5461 gattatggaa tttgccaata aagaaatgga caacgttgtt ttaagtgtcg atggacgtaa
     5521 agaaatccat gattacatgc gtcctacaag aaatggtaag ccaagctatg accttatcat
     5581 gccgaagttt attcgttttg cagagtccag acatcagcag aaatactatg taagaggaac
     5641 atttaccaat agaaatcttg atttctccaa agatgttctt catcttgcag acttaggatt
     5701 tgaacagatt tccatggaac cagttgttgg acagccagaa gagccatacg caattcagga
     5761 aaaagacctt ccacagattt ttgatgagta tgacagactt gcaaaagaaa tgattaagag
     5821 agaaaaagca ggaaaaggct ttaatttctt ccactttatg attgacctta caggtggtcc
     5881 atgtgtagca aaaagacttt ccggctgtgg aagcggaaca gagtatttag cagtaacacc
     5941 atggggagat ttatatcctt gccaccagtt tgtaggagaa gagaaattcc ttcttggtaa
     6001 cgtttttgat ggaatcaagc gtaccgatat ttgtgacgaa ttccgttcct gcaacgtata
     6061 tacaaagaaa aaatgtaaag actgttttgc gagattctac tgtagcggcg gctgtcctgc
     6121 aaactcttat aatttccatg gaacaattga tgattcttat gatttaagtt gcgatatgga
     6181 acgtaagaga gtagaatgcg caattatgat taaggctgca ttagcagata cagaaggcga
     6241 agaagaatag atggaaaagt ggtttatcgc ttcaaaaaga gcagatttta ataaaattgg
     6301 tgagatattt catatcagcc cggtaacggc gcgtctgatg agaaatagga gcttaacaac
     6361 agttggggaa atgcagcgtt atctttatgg ctctctgtct gatttatatg attctcatct
     6421 tttgaaagat gccgataagg gagcggaaat cataagagag aagatagaaa caggcaaaaa
     6481 gattcggatt atttcggatt atgatgtaga tggtgtttca tcaaactata ttttatatca
     6541 gggattaaaa cgctgtggtg cggatgttga ttataagatt cctgaccgtg tggaagacgg
     6601 ttatggaatt aatgaacatc tgatagaaaa ggcagcagag gacgaaattg atacgattat
     6661 cacctgtgac aatggaattg cggcagcaga acagattgct tatggaaatt ctttaggact
     6721 caccctgatt gtgacagatc atcatgatat tccgtttcaa aggcaagaag atggaagcat
     6781 ttcttataat ttgccgtcag ccgctgccgt tattaatccg aagcaaaaag attgtccgta
     6841 tccatttgaa aatatatgcg gagcagttgt tgtctacaag tttattcagg tgctttatga
     6901 tttgtttgga attgaccgta gagaaagtga agcatttctt gagattgcgg cgatggcaac
     6961 agtctgtgac gttatgccat tgtgtgatga gaaccgtatt atcgtaaagg aaggcctgcg
     7021 acggatacag catacgaata ttaccgggct gcaagcttta attgaggcaa atcatcttga
     7081 agaaaaaaag atatcttctt atcactttgg atttattctc ggtccgtgta ttaatgcttc
     7141 cggtcgtttg acctctgcaa aagatgcgtt agaacttctt ctatgcgaag ataaagaact
     7201 ttgcaggcag aaagcagaag cactcacaca gctaaatgca gagcgaaaag aaatgacagc
     7261 taacggggta aaagctgcaa aagaatatct cgaaagcacc ggacatgcaa acgataaggt
     7321 acttgttgta tatcttccaa actgtcacga aagtatcgcc ggaattattg ccggaagaat
     7381 gaaagaacat taccataagc cggtatttgt catcacaaga acaaaagaag gattaaaagg
     7441 ctctggccgt tctatcgaag cctatcatat gtataaggaa atgaacaaaa tcaaggaatg
     7501 tttcgataaa ttcggtgggc acccgatggc agcaggattt tctatgcagg aagaccgctt
     7561 agaagaattc cgggaaaaat taaatgccaa cgcaaccctt accgaggatg atttcgcaga
     7621 aaaagttcac attgatgtag ccttgccgat atcttattta tccgaaagtc tcatcaatga
     7681 atttgaatta ctagaaccat ttggaaatga aaacacaaaa cctctctttg cacaaaaaga
     7741 cctttacata aaaggaatgc gggtactcgg aacaacaggc agatgtttaa aactcttcct
     7801 gtcggatgcc aatggaacaa gcatagatgc catgtatttt ggagaatccg atggattttt
     7861 agaagaactc atctcttttt gtggaaaaga agaggcacag agaattcaaa aaggcctgtc
     7921 acatcatata tggatggatg tgacttatta tccacaggta aatgaatggc gagggcagaa
     7981 gaatatccaa atcgtcatcc agaattatcg ttttaaaaat ttatgagata aattttttag
     8041 tgcttctttc gcatattttt tcgtctgttt agattcccaa ttaataaaaa actatcctaa
     8101 tttgacaaat aaggcgagaa tcaatagaat aatatgagga tgaaaagaga gatacatcaa
     8161 aatcgctatg aattaagaga tagataagga gaaaatatgg aacaggagaa aaaacagcca
     8221 gatgtcagat tgataggatt agatttagat ggaacaacgc tcacttcaga taaggtgtta
     8281 actccacata caaaggaggt acttgagaaa tgtcttgcgg aagggattca ggttttaccg
     8341 gcaacaggaa gagtaaaatc gggtattcca gaatatttaa cacagattga aggaatgaga
     8401 tatgttattt tatccaatgg tgcaagtgta ttagatttaa aagaggataa agttctttat
     8461 cagaattgta ttccgtggga gagagcattg gagttattcg atgtgttaga aacatatgat
     8521 acattttatg atatttatgc attaggagct ggctggtgtg aggctcgctt ttatgataat
     8581 gtagaaaact atggaattga gaaacatatc gagaagctgg ttcgtacatc acgcaatcgt
     8641 attgatgatt taagagagtg gatgaaagaa aataaagctc cagtggagaa gataaatatg
     8701 ttctttgcaa aggaagaaga cagacagaga gctttccgtg aacttggaca gatagaagat
     8761 ttggcggtta cctgttctct tggtaataat cttgagatta atggggcaac ttgtaataaa
     8821 ggagatgcga tgttcaatct tggaaagatt cttgatattc cggcagaaag tattatggca
     8881 tgcggggatg gcaataatga ttttgagatg gttaagatgg ctggtgtcgg tgttgctatg
     8941 aaaaacggag aagagtcttt gaaagaggtt gcagattttg tgacaaagac aaatgatgag
     9001 gagggcgtag catacgctat cgagcatttt tgtaatgtgt aagcagaaat aaacgttttt
     9061 ctgttgtttt ttacataaaa aatctgttat aattaatcat aagaagaaaa agcgcgaaga
     9121 taaaagtctg tgcttaatag ttttatgcct gatttggggc agaaagggtg gacaaagtga
     9181 aaaaacttga agattatgtc attaatattc cagatttccc aaagccggga attattttca
     9241 gagatattac ctctatttta cgtgatccgg agggactgaa acttagcgta catgaattaa
     9301 tgcattgctt agagggaaca gagtttgacg tagttgttgg agcagaatcc cgtggatttt
     9361 tatttggtat gcctcttgct tacaataaaa gcaagggatt tgttcctgtc cgtaagaaag
     9421 gaaagctgcc aagagagact gtaagcaaag aatatgcttt agagtatgga acagcagaga
     9481 ttgaaatcca taaagaggac attcgtccag gacaaagaat cgtatttgtg gatgaccttt
     9541 tagcaactgg tggaacagca aaggctgcga ttgatctgat cgaagaactt ggtggcgttg
     9601 tcgtaaaggt tctgtttgtt atggaacttg agggattgca tggccgtgat gtattaaaag
     9661 gctatgatgt agattctgtt attacttatc ctggaaagta attttgaagg aaaagaaact
     9721 gtgtggatgg aattttttgg aagcacagtt tctctttgtg taaaaattgt tctgtagtta
     9781 taaagttgaa tttctatttg caatttcttt ctttaaatcc tgcattttgc tttacaaaaa
     9841 gaagaaaatg gagtattatg aaatatactt aattttacag aataggtgga agaatagagt
     9901 ggaacattta aatttattac agagaataga gaagaagtct tccgagttca gtaaaggaca
     9961 gagaagactg gctcagtata ttacagagaa ctatgatatt gcagcgtata ttactgcttc
    10021 aaagcttgga aaggaagcag gagtcagtga gtctacagtg gttcgttttg cctatcagct
    10081 tgattacgag ggatatccag agctgcagaa ggcaattcag gttattgtaa agacaaactc
    10141 aaactccatt cagagaatgt ccctttcctc aaaaagatat caggaaaaag gtgtattaaa
    10201 gagtattttg tatacagatt cagagcggct tcgcgatacg attcagagcg gtgtagatga
    10261 ggaagaattt aacagatccg ttatgcttat caatgatgca agaagattgt atattttagg
    10321 tgcgagaagt gcagcctatc ttgccggtct gatgggatat tattttaaga tgatgtttga
    10381 caatgtaatt atcgtagatg ccaacagcac gtccgagaca ttagagcaga tttacgatat
    10441 cagtgataag gatgttatga tgggaattac tttcccaaga tattcaaaga gaaccatctg
    10501 tgcgcttcag tatgcgaaga atcatggagc gaagacaatc gcacttaccg acaatatgca
    10561 gtctccaatt gtagagtatg cagattgtaa attgattgca aagagtgatg taatgacaat
    10621 cgtggattct ttagtatgtc cgttaagtgt ggtgaatgcg atggttacag cgattgcatt
    10681 gcttcgtaag gatgatgtag agaagcgtct tatggcactt gaagaactct ggaacgagta
    10741 tgatgtttat aacaggagtt tactataatg aacaaagtaa ttattgtagg cggaggggca
    10801 gccggtatga tggctgccat ttctgcgtct aaagagggga aaaaggcctg cattcttgaa
    10861 aagaacgaaa aacttggcaa gaagcttttt attacgggga aaggcagatg caatattaca
    10921 aatgcctgtc cggcagacga atttcttact catgtggtaa caaatccaag atttttatac
    10981 agtacatttt cgcagtttaa taatgaggat atgatggact atttagaaga aatcggtctt
    11041 ccgataaaga cagagagagg acagagagta tttccacag
//
