LOCUS       c00036_gnlPro..        13222 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HFCOLFJE_36.
ACCESSION   c00036_gnlPro..
VERSION     c00036_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:19:29
            Original ID  :: gnl|Prokka|HFCOLFJE_36
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 31244
            Orig. end    :: 44466
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13222
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[41244:44465]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13221
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13222
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13222
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             346..558
                     /locus_tag="ctg36_31"
                     /transl_table=11
                     /translation="MEKHIEKRGLHHIWQNQFSYKLMSNLNVLINKTQIGHLSNVQTKG
                     NVLLSTYNKLLYEHPHYRSPRFRRL"
     CDS             515..1501
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_HSD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg36_32"
                     /sec_met_domain="Beta_HSD (E-value: 7.1e-11, bitscore:
                     33.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 1.3e-18, bitscore:
                     58.9, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNILITGVHGFVGSNLVKALAPENTIYGLDIVAPEKEGVIKTFSW
                     DDLGSIDFPQINVVIHLAGKAHDTRNKSVADVYFKVNTGLTQRIFDWFLTNGSAKKFIF
                     FSTVKSASDKVEGKCLTEECVPTPVGPYGESKIKAEDYIIGHFAPEALKRPYHNFDDGD
                     SLVKGKNVYIIRPCMIHGPGNKGNLNLLYGVVSKGIPWPLGAFENHRSFTSIGNLCVVI
                     DGFLTKNVPSGIYHMGDDEALSTNELIQVICEALGKKAHIWCIPKGLMNGVAKVGGWFH
                     LPLNPLRMQKLTENYVVSNAKIKAALGITRMPVRAKDGLMDTIRSFK"
     CDS             1506..2510
                     /locus_tag="ctg36_33"
                     /transl_table=11
                     /translation="MIMNAYLTYGIIFVILLALELCYFKVADHFNIIDKPNERSSHSTI
                     VLRGGGIIFLIGIWIWSAFFGFQYPWFLAGLTLVAGISFVDDIHSLPDSVRLIAQFAAA
                     AMAFYQLGILHWSMWWIILLALIVYVGATNVINFMDGINGITAGYSLAVLIPLALVNIN
                     GVFVEQSLIISTILASLVFCIFNFRPKGKAKCFAGDVGSIGIAFIILFLLGNVMIRTTD
                     ITWLIFLLVYGVDGCLTIVHRIMLHENLGEAHRKHAYQIMANELKVGHVKVSLLYTVMQ
                     LVISLGFIYLCPDTVFAHWLYLVGVSAVLAIAYILFMRKYYHLHEEYLISLKQ"
     CDS             2516..2953
                     /locus_tag="ctg36_34"
                     /transl_table=11
                     /translation="MEFNKEFLDKLFEQATENPRLRQNFDLRTSSADTSQRMLNALLPE
                     TKVPIHRHEDTTETVICLCGSLDEVIYEEVVSYENDTNDFQKGMNVQDVVRKVEYREVQ
                     RIHLNPTETKYGCQIPKGAWHTVEVIEPSVIFEAKDGAYAR"
     CDS             complement(3229..3651)
                     /locus_tag="ctg36_35"
                     /transl_table=11
                     /translation="MRTITLIIIHCSATPEGKSLSAEACRQDHILHRGFRDMGYHFYIT
                     RDGEIHRGRALEKVGAHCRNHNAHSIGVCYEGGLDANGKPKDTRTLEQEGALLALLREL
                     KRQFPKALIVGHRDLNPMKGCPCFDAVKEYAEIASF"
     CDS             complement(3927..4421)
                     /locus_tag="ctg36_36"
                     /transl_table=11
                     /translation="MIRYKIYQNQQKKGLNAGKWFARAVSDETFDLAKLAEHMSKHNSP
                     YSGGVIKGVLSDMVDCIKELLLDGKCVKIDDLAIFGVGIRSKAADTLEEFSLEKNISGM
                     RLKARATGNLSTNNLKLDSQLKQQAEYQKPTTAGEGSDSGDNPDPKPDGGGEGEAPDPA
                     A"
     CDS             4641..4859
                     /locus_tag="ctg36_37"
                     /transl_table=11
                     /translation="MNEFKIRAYGRMELAQLYSPELTDIAAYRKMKKWISLCPGLLQRL
                     YDLGYESKRRSFTPLEVRVIVDALGEP"
     CDS             complement(4904..5038)
                     /locus_tag="ctg36_38"
                     /transl_table=11
                     /translation="VKRGKCPHCPRLPCCNRLDRYTHFDYRIRFYCIKHRFRRCKAKL"
     CDS             complement(5035..6861)
                     /locus_tag="ctg36_39"
                     /transl_table=11
                     /translation="MTDIESLRRLTEAVETAGADIAPTYLEYVQLSFAIATDCGEAGRE
                     FFHRLCRVSPKYQREHAERVFSNALHTQRGEVHLGTAFHLAEATGVAISYVETVGTVGT
                     APQILTQARAYNKVANEETDEETITEEKEELLSGSDPQHPLPTLSEANWPKLLQRIIKV
                     AKSEIQRDIMLMGAFTALGACMSRHVRCLYGGKYYYPSLQCFIVAPSASGKGILSYLRL
                     LVQPIHDEIRAKVAEQMKIYKKEKAEYDAMGKERSKMEVPQMPPNKMFLISGNNTGTGI
                     LQNIMDSEGTGLIFESEADTLSTAIGSEHGHWSDTLRKAFDHDFLSYNRRGNQEYRETK
                     KVCLSLLMSGTPLQVKAFIPTTEDGGSSRQLYYYMYGIDKWVSQFVDDETDWEEVFNAL
                     GLEWKKQLDVIKKNGIHTLQLTNEQKSEIDAVFSELFDRSSIANDREMYSFVARMAINL
                     CRIMSEVAVLRALEHPNPYSLQISSSSPFTPDKSIPSDNRKDGIVTRWNVSISAEDFHA
                     VLNLAEPLYCHAMHILSFLPNTEVSHRPNADRDFLFQQLGKEFTRTELLEKATALGINK
                     STAITWLKRLTRQGKLISVDGKGSYARACVYE"
     CDS             complement(6889..7521)
                     /locus_tag="ctg36_40"
                     /transl_table=11
                     /translation="MMPNNYRMSYFMPPIAPIKDKQGRLMTPPTLIPFCEVSIEQVFQM
                     ITCNENLKALTEQVRNSEDIRTAKASLLPYVTPCGTFTRRSSKDFVSPSHLVIVDVDGL
                     HSYQEAVEMRRMLYDDPLLQPVLTFVSPSGLGVKAFVPCHYSSTTNDIPNITDNMSWAM
                     RYVETAYNTVTAVSSETKSKVDFSGKDLVRSCFLSYDPEALFRTTNE"
     CDS             7686..7838
                     /locus_tag="ctg36_41"
                     /transl_table=11
                     /translation="MENEKGLYVALGVYIGELQKRADLKNDEIRKSVHIGHSTFNDLKK
                     GQNAH"
     CDS             8118..9284
                     /locus_tag="ctg36_42"
                     /transl_table=11
                     /translation="MSSKIYPIGIQNFEKIRKDGYFYIDKTALIYQMVKTGSYYFLSRP
                     RRFGKSLLISTLEAYFLGKKELFEGLAMEKLEKDWITYPIFHIDLNTEKYDTRDSLDSI
                     LNFTLEKWEQQYGTAPSETTFALRFRGLIERAYEQTGQRVVILIDEYDKPMLQAIGNEE
                     LQKEFRNTMKAFYSVLKTMDGCIQFAFLTGVTRFGKVSVFSDLNNLDDISMRKQYVDIC
                     GVSEKELHDNLEIELHELADAKELTYGELCNRLREYYDGYHFTYNSIGIYNPFSLLNTF
                     KYREFGSYWFETGTPTYLVELLKKHHYDLERMAHEETSAAVLNSIDSTSDNPIPVIYQS
                     GYLTIKGYDEEFGIYSLGFPNREVEEGFIKFLLPFYANTNAVESEFEI"
     CDS             9568..9993
                     /locus_tag="ctg36_43"
                     /transl_table=11
                     /translation="MTNNTIKHLGIVENIQGSHLSVRIVQTSACAACSAKGHCSSADSK
                     DKIIDIIDTAASSYQVGEKVMVVGETSMGMMAVVLAFVLPFVLLIFSLFLLMAWIENEL
                     YAALLSLAVLIPYYFVLWLNKTRLKQQFSFTIKPINN"
     CDS             10001..10882
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.6; E-value:
                     4e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_44"
                     /sec_met_domain="Fer4_7 (E-value: 3e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1e-08, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 2.1e-08, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9.8e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 3.5e-08, bitscore: 25.6,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 8.7e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-05, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMIAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             10907..12244
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_45"
                     /sec_met_domain="Fer4_10 (E-value: 4.5e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.7e-16, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9.4e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5.9e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.2e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             12250..13221
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg36_46"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.5e-117,
                     bitscore: 383.7, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIHAADKSAAMDALNQIPDALSLLIGQNGGCLGEVSALALLIGLVYMLWKKIIT
                     WHIPVSILATVFIFAGIMHLADPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGM
                     LIYGVCIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCK"
ORIGIN
        1 aggttctaat ggtcaactaa aaaataagat gcgtatcatt aataaagagg gtatagataa
       61 gtatatcttt actgatatta caacaagaag gtgtagagac tagtattttg acataacgga
      121 ttttgaagct attcgtgaga tagtagctga gtatctggta aatgcaatcg taacgatttt
      181 atctactact tagcgactcc tccactaata tcaatcttaa aggcgatcct tttttatcca
      241 ttcgatttat ctaaagtttc aagtcataaa tctgaataga atttccgcta ttgaagaccg
      301 ttctaaattt tttgatgcaa ttgacatggt ttcttaacga gaactatgga gaagcatatt
      361 gagaaaagag gactacatca catctggcag aatcagttta gctacaagct aatgtcaaat
      421 ttaaatgtat taattaacaa aactcaaatt gggcatcttt caaatgttca aacaaagggt
      481 aatgtccttt tgagtactta caataagtta ttatatgaac atcctcatta ccggagtcca
      541 cggtttcgtc ggctctaatt tagtgaaggc tctcgcgcct gagaatacaa tatatggttt
      601 ggatattgta gctcctgaga aggaaggtgt aataaagact ttctcatggg acgatctagg
      661 cagtattgac ttcccgcaga ttaatgttgt tattcatctt gcgggtaagg cccatgacac
      721 tcgcaataag agtgtggcgg atgtgtattt caaagtaaat acaggtctta ctcaacgtat
      781 ttttgattgg tttcttacca atgggtcagc aaagaaattt atatttttct ctacagtaaa
      841 gagtgcttca gacaaagtag aaggcaaatg ccttacagaa gaatgcgttc ccactcccgt
      901 aggcccttat ggagagagta aaattaaagc ggaggattat ataatcgggc attttgcccc
      961 tgaagcactt aaacgtcctt atcacaattt tgatgatggc gactctcttg taaaagggaa
     1021 gaatgtatac attatacgcc cttgtatgat tcacggacct ggaaacaagg gtaacctcaa
     1081 tcttctttat ggagtagtga gcaaggggat tccatggcct cttggtgctt ttgagaatca
     1141 tcggtcgttt actagtattg gaaatctttg tgtagtaatt gacggatttt taactaagaa
     1201 tgtaccttca ggtatttatc atatgggaga cgatgaagct ctttcaacta atgaactcat
     1261 tcaagttatt tgtgaggctc ttggtaagaa agctcatata tggtgcattc cgaaaggtct
     1321 gatgaacgga gttgcaaaag tgggtgggtg gtttcatctt ccgcttaatc ctcttcgaat
     1381 gcagaaactc acagaaaact atgtagtgag taatgccaag atcaaggctg ctcttggcat
     1441 tacgcggatg ccggtaagag cgaaggatgg attgatggac actattagaa gttttaagta
     1501 gtagaatgat tatgaatgca tacttgactt acggaattat ttttgtgatt ctattggcat
     1561 tagagttatg ctatttcaag gtggctgacc actttaatat tatcgacaaa cccaacgaac
     1621 gctcatcaca ctctacgatt gtattgcgtg gcggaggtat aatctttttg attgggatat
     1681 ggatttggag tgccttcttc ggattccaat atccttggtt cttagccggt ttgacattag
     1741 tagccggcat tagttttgta gatgacatcc attcattgcc ggactctgta agattaatag
     1801 cccagtttgc agctgccgca atggcattct atcagctcgg catattgcat tggtcaatgt
     1861 ggtggataat attactggca ctaatcgtct atgtcggtgc cacgaatgtg ataaacttca
     1921 tggatggaat caatggtatc acagcaggct actctttggc tgtattgatt ccgttggcac
     1981 tggtgaatat aaatggtgtt tttgtagaac agagtttgat catatcaacg attcttgctt
     2041 cattggtgtt ttgtattttc aatttccgtc cgaagggtaa agcgaaatgc tttgcagggg
     2101 atgtcggctc tattggtatt gcttttatta tactgtttct gctaggtaat gtgatgatca
     2161 ggacaacgga tattacttgg ctgatattct tgttagtata tggtgtggat ggctgtctga
     2221 ctattgtaca tcgtattatg ttgcacgaga acttgggcga ggcacatcgt aagcatgctt
     2281 atcagattat ggctaatgag ttgaaagtgg ggcatgtaaa agtttcattg ctgtatacgg
     2341 ttatgcagtt agtgatttct cttggattta tctatctttg tcccgatacg gtgtttgctc
     2401 attggttata tttggtgggt gtatcagctg tattggctat tgcttacata ttgttcatga
     2461 gaaaatacta tcatttacat gaagaatatc tcatatcatt gaaacaataa cgattatgga
     2521 atttaataag gaatttttag acaagctatt tgaacaggcc acagaaaatc ctcgtttgcg
     2581 tcagaacttt gacctacgca cttcatctgc cgataccagt caacgtatgc taaacgcatt
     2641 gctgccagaa actaaagtgc ccattcatcg gcatgaagat actaccgaaa cagtaatctg
     2701 cctgtgtggc agtttggacg aagtaattta tgaggaagta gtttcatatg agaatgatac
     2761 gaatgatttt cagaagggga tgaatgtgca agatgtagtt cgtaaggtgg agtatcgaga
     2821 agtacagcgt atccatctca atcctacaga aaccaaatat ggttgtcaga taccaaaggg
     2881 tgcatggcat actgtggaag tgattgaacc atctgtcatc tttgaggcta aagatggagc
     2941 ttatgctcgt taaacgatga aaaacagatg aaatgaatag gaagtactga aagtgctttt
     3001 taatacgtta tgttataatt gaacatttac aatggaatga aaaaatgtag gtccctagat
     3061 tcatgtgaca aacataaatc cctacattta gtagattagg agcaatatag tgatattgtc
     3121 ctaatctcgc tcttcatatt agtgttaaca ctaatatgat ttccaaaaat accaactgtc
     3181 tgtgaagatc gttgatattt ttttatacaa taagacagtg gtggaaatct aaaaggatgc
     3241 tatttctgca tactctttca ccgcatcaaa gcatggacat cctttcattg gattcaagtc
     3301 ccggtgtccc acaatcaacg ctttcggaaa ctgccttttc aactccctca acaaggcaag
     3361 cagggctcct tcttgctcca atgtacgcgt atctttcggt ttcccgttcg catccaatcc
     3421 tccctcataa caaacaccta tcgaatgggc attatgatta cggcagtgtg ccccgacctt
     3481 ttctaacgca cgtccccggt gaatctcccc atcgcgagta atgtaaaaat gatagcccat
     3541 atcgcggaaa ccacggtgca agatatgatc ctgtcggcaa gcttccgccg aaagggactt
     3601 tccttccggc gtggcactgc aatgaatgat aattaatgta atagtccgca tgggggttac
     3661 atgcaacttt gtattccgaa cacacctccg atggcggtgg ctacagtgat aatgattttg
     3721 agaactaagc tccatacgga gcggggagat gatgaattac tcataataag aggttttgaa
     3781 taaattaata atagttttct ttgtcacaga tttactatag atttaccaca gatctacaca
     3841 gactcacaca gataaataat cgactacttt agtaactacc aattcaatat aatctgtgga
     3901 aatctgtgta atctgtggtg aaccttttaa gcagccggat caggagcttc tccttcgcca
     3961 cctccgtccg gtttcggatc agggttgtca cccgaatcag aaccttctcc ggcggttgtc
     4021 ggtttctgat actccgcctg ctgcttcaac tgactgtcga gtttcagatt attagtcgac
     4081 agattaccgg tagcacgagc tttcagacgc ataccgctaa tattcttttc caacgagaac
     4141 tcttccagcg tatcggctgc cttactacga atacccacac caaaaatggc aagatcatca
     4201 attttcacac acttgccgtc tagcaacaat tccttgatgc aatctaccat atccgaaagc
     4261 acacctttga tgaccccacc ggaatacggt gaattgtgct tcgacatatg ttcggcaagc
     4321 ttagccaaat caaacgtctc atcgcttact gcacgggcga accacttacc cgcattcaaa
     4381 cctttcttct gctggttctg ataaattttg taacgaatca taaaacaata aattaaaggg
     4441 ttaaacagat tgtccgggga ttcttttccc tttcgacgat acaaagatac caccctcaaa
     4501 ctctggaaaa tcaatagtac acagttgcgt acaattgttg tcggttgtgt gcaattatga
     4561 tcgattattc aatgaaaagg cgttggctat gtagaaatat tttgctattt ttgtaactgt
     4621 aaatcagaaa tttatccatt atgaacgaat tcaaaatacg tgcctacggg cgcatggagc
     4681 tggcgcaact ctattctccg gaacttaccg atattgccgc ttatcgaaaa atgaagaaat
     4741 ggatctctct atgtcccgga cttctgcaac gcctgtacga cttaggctac gaatcaaagc
     4801 gacgctcatt cacaccattg gaggtgagag tgattgtgga tgccctggga gagccttaaa
     4861 taatgcggca ctttatgatg cataaagcac cgctttacga tgtctaaagc ttagctttac
     4921 acctcctaaa gcgatgcttt atgcagtaaa aacggatgcg gtaatcaaaa tgagtgtacc
     4981 ggtccaaacg attacagcaa ggaaggcggg gacagtgggg acactttccc cgtttcactc
     5041 atacacacac gcacgcgcgt aactcccttt gccgtctaca ctgattagct tgccttgtcg
     5101 ggtgagacgt ttcagccagg tgatggcggt acttttgttg atacccagag ctgttgcttt
     5161 ttccagcaat tccgtgcggg taaattcctt acccagttgc tggaagagga aatcccggtc
     5221 ggcattgggg cggtggctga cttcagtgtt ggggaggaat gacaggatat gcatggcgtg
     5281 acagtagaga ggttccgcca aatttaatac ggcgtggaag tcttccgccg agatggatac
     5341 gttccagcgg gtgacgatgc cgtccttgcg gttgtccgaa ggaatagact tgtcgggtgt
     5401 gaagggggag gaggaggaaa tttggaggct gtagggattc gggtgttcga gcgcgcgcaa
     5461 cacggctact tccgacatga tcctgcacaa attgatagcc atacgcgcca caaagctata
     5521 catttctctg tcgttggcta tgctcgaacg atcgaacaac tccgaaaaga cggcgtcaat
     5581 ttcgcttttc tgctcgttcg tgagctgcag cgtgtggata ccattcttct ttatcacgtc
     5641 cagttgtttt ttccattcca gtcctagagc gttgaatacc tcttcccagt ctgtttcgtc
     5701 gtctacaaac tggctgaccc atttgtcgat tccgtacatg tagtagtaca actggcggga
     5761 ggatcctccg tcttccgttg tcgggatgaa ggctttcact tggagtgggg tgcccgacat
     5821 caggagcgaa aggcagactt tttttgtttc ccgatattct tggttaccgc gacggttgta
     5881 ggacaagaag tcgtggtcga acgctttgcg cagcgtgtcg ctccaatggc cgtgttccga
     5941 tccgatggcg gtggacagtg tgtcggcttc cgactcgaag ataagtcctg taccttcgga
     6001 gtccataatg ttttgtagga tgcctgtgcc ggtgttgttg cccgaaatca agaacatttt
     6061 gttagggggc atttgcggga cttccatttt cgaccgctct tttcccatcg cgtcgtattc
     6121 ggctttttct tttttataga tcttcatttg ctccgccact ttcgcgcgaa tctcgtcatg
     6181 gatgggttgc acgagcaggc ggaggtagga gaggatgcct ttgccggaag cagagggcgc
     6241 cacgatgaaa cattggaggc tgggataata gtatttgccg ccatagaggc atcgcacgtg
     6301 gcgcgacatg caagctccca gcgcggtgaa tgctcccatc agcatgatgt cgcgttgaat
     6361 ctcacttttc gcaactttga tgatacgctg caggagtttc ggccagtttg cttccgacag
     6421 agtggggagc gggtgttgcg gatcgctacc ggatagcagt tcttcttttt cttccgtgat
     6481 cgtttcttcg tctgtttcct catttgccac cttattatac gcgcgtgcct gtgtgagaat
     6541 ttgaggggct gtccccactg tccccactgt ctccacatag ctgatggcga ctcccgtcgc
     6601 ttcggccagg tggaaagcgg tgcccaggtg cacttctcca cgttgggtgt ggagtgcgtt
     6661 ggagaatacc cgttcggcat gttcgcgctg atacttggga gacaccctgc ataggcggtg
     6721 aaaaaactca cgtcctgctt cgccgcaatc cgttgcgatg gcgaatgaca attgtacgta
     6781 ttcaagataa gtgggagcaa tgtccgctcc tgccgtttcg actgcttcgg tgagacggcg
     6841 taaagattca atatcggtca ttttgattta tgatttttga tttatgattt attcgttggt
     6901 ggttctgaac aatgcttccg ggtcgtaact aaggaaacag gatctcacga ggtctttgcc
     6961 ggagaaatct actttggatt ttgtttcgga agaaactgct gttaccgtat tgtatgccgt
     7021 ctctacgtac cgcatcgccc aactcatgtt gtctgtgata tttgggatgt catttgtcgt
     7081 ggaggaataa tggcagggaa caaatgcctt tacacccagt ccgctggggc tgacaaaggt
     7141 gagtacaggt tgtaggagag gatcgtcata gagcatacgt cgcatttcca ctgcttcctg
     7201 ataagagtgg agaccgtcca catctactat caccaggtga gacggggaga cgaaatcctt
     7261 actgctacgg cgggtgaatg tgccgcaggg ggtcacatac ggtagtaatg acgctttggc
     7321 ggttcgtata tcttcggagt tgcgcacttg ttcggtcagg gctttgagat tctcgttgca
     7381 agtaatcatt tggaaaactt gttcgatgga gacttcgcag aaggggataa gcgtgggagg
     7441 agtcatcagt cggccttgtt tgtctttgat aggagcgata ggtggcatga aataggacat
     7501 tctgtagttg tttggcatca ttttcttttt gtttcaagtt aaaatgttta tttttgcaaa
     7561 aaaatatgag tgtgtttcaa aacacggcgt aaaattagta aatgcaaaat agacatcgtc
     7621 ccgacatgtt gggatgaaag tgaaaataat taaccgttac ggtgtaattt taacaataaa
     7681 aaagaatgga aaatgaaaaa ggtttatatg tagctttagg agtttacata ggagagttgc
     7741 aaaagcgtgc ggatttgaaa aatgacgaaa tacggaagag cgtacacatc ggccactcta
     7801 cttttaatga tttaaaaaag gggcaaaacg cccattgagt gattacgtaa aagtggtgga
     7861 gtgctgtctg gatgccttca atgaagagga agccggagtt atctgggatg aatggaggag
     7921 aatgtatttt cgatacagaa gaagaaaaga ggaggagaga ggagaacggt gaaaaaacag
     7981 ataaggtaaa agtggcaggc gggaaaaagt ttcccgcctg cggtctttat gaatggattt
     8041 ttttgtagct ttgtgaaaaa taagattgat atggaagatt tgtctggtaa tttttataat
     8101 ttaagaaaaa gaagcgtatg agtagcaaga tataccccat tggcatacag aactttgaaa
     8161 aaatccggaa agacggttat ttctatattg ataagactgc tttgatttat cagatggtga
     8221 agacaggcag ttattatttc ttgagccgtc cccgtcgttt tggaaaaagt ctgttgatat
     8281 ctacgcttga agcgtatttc ttgggcaaga aagaactttt tgagggcttg gccatggaaa
     8341 agctggaaaa ggattggatt acatatccta tttttcatat cgatcttaat acggagaagt
     8401 atgatacgcg ggatagcctg gacagcatat tgaatttcac attggagaaa tgggaacagc
     8461 aatatggcac cgccccgtcg gaaacaactt ttgcattgcg ttttcgcggc cttattgaac
     8521 gggcttatga gcaaaccggg cagcgtgtgg tcattctgat agatgaatat gataagccca
     8581 tgttacaagc aataggtaac gaggagcttc agaaggaatt ccgtaatacc atgaaagctt
     8641 tttatagtgt gctgaagact atggacggtt gcattcagtt tgcttttctg acgggagtga
     8701 cgagattcgg taaggtaagc gtgttcagcg atttaaataa tctcgatgac atctcaatgc
     8761 ggaagcaata cgtggatatt tgcggagttt ctgaaaaaga attgcatgat aatttggaaa
     8821 ttgaactgca tgaactggcg gatgcaaagg agctgactta tggtgaactg tgcaatagat
     8881 tgagggagta ctatgatggc tatcatttta catacaattc tatcggaata tataatccgt
     8941 tcagcttgct taatactttt aaatatagag agttcggtag ttattggttt gaaacgggaa
     9001 ctcctactta tctagtggag ttgctgaaaa aacatcatta tgacttggaa cgtatggcgc
     9061 atgaggaaac gagtgccgct gtattgaaca gtattgattc aacatcggac aatcccattc
     9121 cggtcattta tcagagcggt tatctcacta taaaagggta tgacgaagaa tttggaattt
     9181 atagtttagg cttccctaat cgcgaagtag aggaaggatt tattaaattt ttgcttccct
     9241 tttatgcgaa caccaatgcg gtagagtcgg agtttgaaat atagaacttt aacgcgaaaa
     9301 tgcggaatat tgagagatgg atagtgggat aatggtgaaa taacgataga aaatcccggt
     9361 tgaatgaata aaacggccgg gattttcttg tttaaaatgt ttgtttgcca ctcttgaaaa
     9421 atatcaaatg gtagctatat cttttccgtg tgcgataacg aaaacgcaaa aaataacaat
     9481 ttattatgta gaaaaagttg ggggaatgct tcgtagttca caaataatga ttaaatttgc
     9541 cgcgatttgt aatgcggagt ttgcaaaatg acgaataata ctataaagca tctaggtatt
     9601 gtggaaaaca tccaaggttc tcatctgtcg gtgaggattg tccagacatc ggcttgcgcg
     9661 gcttgtagcg caaaggggca ttgttcctcg gcggatagta aggacaaaat catagatatt
     9721 atagataccg cggcttcttc ctatcaggtg ggagagaagg tgatggtggt cggcgaaacg
     9781 tcgatgggca tgatggcagt ggtattggct ttcgtacttc ctttcgtact tcttatattt
     9841 tcattgtttc ttttgatggc gtggatagag aatgagttgt atgcagcact tctttctctg
     9901 gctgtcctta taccttatta tttcgttttg tggctcaata aaacgcgact caaacaacaa
     9961 ttttcattta ctataaaacc aataaataac taaaaacatt atgaatttga ttctgattgc
    10021 agtgatttca ttgggagcta tagcgctcgt gctggccgct attctttatg tagcttccaa
    10081 gaaatttgcc gtgtatgaag acccgcggat tgcccaggtg ggggaagtgt tgccccaggc
    10141 aaactgtggt ggatgtggct atcctggttg tagcggattt gccgatgctt gcgtcaaagc
    10201 cggttcgctg gatggtaaat tctgccctgt aggcggtcag cctgtcatgg cacaaattgc
    10261 tgatattctc ggactggcag ctactgaagc tgaaccgatg atagcagtag taagatgtaa
    10321 cggaagctgt gccaatcgtc cgcgtattaa tcaatacgac ggtgcgaaga gttgcgctat
    10381 tgccgcttca ttgtatggtg gagaaacagg ttgtagctac ggatgcctcg gatgtggcga
    10441 ctgtgtggct gcctgccagt ttgacgctat ccacatgaat cctgaaacgg gacttccgga
    10501 agtggatgaa gccaaatgta cagcttgtgg cgcttgtgtg aaggcttgtc cgaaggcgat
    10561 catcgagatt cgtccgcaag gcaagaaatc acgccgtgtg tacatctctt gtgtgaacaa
    10621 agacaaggga gccgtagcac gtaaggcttg tacagtgagc tgtatcggct gtggtaagtg
    10681 tgtcaagact tgtccgttcg aagccattac gctggagaac aacctggctt acatcgatcc
    10741 gaacaagtgt aaatcatgcc gtaagtgcgt ggaagtttgt ccgcagaaca cgattatcga
    10801 gctgaacttc cctccacgta aaccgaaggc ggaagaagca ccgaaaacag ttgctgcaga
    10861 agctccgaag gtaacagaat aataacagaa taaaatacag aattgtatgt taaagacatt
    10921 ttcaattggt ggagttcatc cacacgaaaa taaattgtcg gcacatcaac ctatcatcac
    10981 agcggaagtt cctgcaaagg cagttattct gttggggcag cacattggcg cacctgccaa
    11041 accgatagta gcaaaaggtg atatggtgaa ggtaggcacg aagattgccg aacctgccgg
    11101 cttcgtttcg gcagcaattc actcttctgt cagtggaaaa gtggcgaaga ttgatacagt
    11161 agtcgatgcg agcggttatg caaaacctgc tatctttatt gatgtagaag gcgacgaatg
    11221 ggaagaaacc attgaccgta gcaagacact ggtcaaagaa tgtgagcttt cgtccgaaga
    11281 aatcgtgaag aagattgccg atgccggtat cgtaggtttg ggtggtgctt gtttccctac
    11341 acaggtgaaa ctttgtccgc ctccttcgtt caaggcagaa tgtgtgatta tcaatgcggt
    11401 ggaatgtgaa ccgtatctga ctgccgacca tcagctgatg ctggaacacg cggaagaagt
    11461 catggtaggt gtctccattc tgatgaaagc cgtgaaggta aataaggcat ttatcggaat
    11521 tgagaataac aagccggatg ctattgaact gatgacgaaa gttgcttcca gttatgcagg
    11581 catcgaagtt gttcctttga aagtgaaata tcctcagggt ggtgagaaac agttgattga
    11641 tgcgattacc aaacgccagg tggcaagtgg tgcgctgcct atctctactg gggcagttgt
    11701 gcagaatgtg ggtacggcat ttgctgttta tgaagctgtt cagaaaaata aaccgttgtt
    11761 tgagcgtgtg attaccgtaa ctggtaagtc tgtggccaaa ccttccaact tcctggctcg
    11821 tatcggtaca ccaatgaaac agctgattga tgcttgtggc ggtctgccgg aggatacggg
    11881 aaaagtgatc ggtggcggtc cgatgatggg taaggctctg gtgaatatcg aagttcctac
    11941 cgcaaaaggc agttccggta tcctgattat gaatcagaag gaagccaaac gtggtgaagc
    12001 acaaacctgt atccgttgtg caaagtgtgt gagcgcttgt ccgatgggac tggagccgta
    12061 cttgctcgga gctttgtccg aaaacggaga ttttgaaaca atggaaaaag aaagaatcat
    12121 ggattgtatc gagtgcggct cttgccagtt cacttgtcct gccaaccgtc cgttgctcga
    12181 ctactgtcgt ctgggcaaag gtaaagtagg tgctatgatt cgtgcacgtc aagctaaaaa
    12241 ataacgaata tggaaaataa attaatcgta tcactatcac cccacgttca tggcggagac
    12301 agcgtacaga aaaatatgta tggcgtgctg atcgcactga ttccggcttt tctggtgtct
    12361 ctctatttct tcggactggg tgccctgatt gtcacggcta cttccgttgc agcttgtttg
    12421 ttcttcgaat gggcgatcgg gaaatattta atgaagaaac ctaccactac catctgtgac
    12481 ggctctgcca tcatcacagg tgtgttgctg gcattcaact taccgtctaa tctccctatc
    12541 tggattatca ttctgggtgc actgtttgct atcggtgtag gcaaaatgtc tttcggcgga
    12601 ttaggttgca atccttttaa tccggcactg gcaggacgtg tgttcctgtt gctttctttc
    12661 ccggtgcaga tgaccagctg gccggtagtc ggacagttga ccgcttatac ggatgctacc
    12721 accggtgcca ctccgctggc attgatgaaa caagcgattc atgctgcaga taagagtgcg
    12781 gctatggatg ctttaaacca gattccggat gcattgagtt tgctgatcgg acagaatggc
    12841 ggatgcttgg gtgaagtgag tgcattggct ctattgatcg gactggttta tatgctctgg
    12901 aagaagatca tcacgtggca tattcctgtg tctatcctgg ctaccgtgtt tatctttgca
    12961 ggtatcatgc acttggcaga tccggaaaaa tatgtttctc cggtattgca gttgctctcc
    13021 ggtggtctga tgctgggtgc tgtctttatg gcaaccgact atgtgacttc tccgatgagt
    13081 aagaaaggaa tgttgattta tggtgtatgt atcggtctgc tgacggttgt catccgtctg
    13141 ttcggtgctt atcccgaagg tatgtcgttc gccatcctga ttatgaatgc gttcactccg
    13201 ctgattaaca cctattgtaa ac
//
