LOCUS       c00018_gnlPro..        13437 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDFKIGGP_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:03:35
            Original ID  :: gnl|Prokka|FDFKIGGP_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13437
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13437
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3437]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3437
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13437
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13437
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..671
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="SucD_FumR (E-value: 1.1e-120, bitscore:
                     392.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GRKVVMSVTGIALVLFLTFHMAMNLVAIISAEGYNLVCEFLGANW
                     YALVATLGLAALFVIHIIYAFWLTIQNRAARGSERYAVVDKPKTVEWASQNMLVLGIIV
                     ILGLGLHLFNFWAKMQLPELVHNMGGVADTTYAADGVYHIMNTFSNPVYVVLYLVWLGA
                     LWFHLTHGFWSSMQSLGWNNKIWINRWKCISNIYSTIVVVCFALVVVVFFVKSLACGAC
                     "
     CDS             709..2652
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.1; E-value:
                     1.8e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 2e-60, bitscore:
                     197.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 121.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGQLAEKWSNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFARDYGGTLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQVQKGTVKLYTRYEMLDLVVIEGRARGIIARNLVTGEIERFAAHA
                     VVIGTGGYGNAFFLSTNAMGSNGSVAIQCYKKGAYFANPCFAQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKIEDAKALQAGTKKPTEIPDEDRDFYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEITDENPYK
                     TPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKHSVDSIHKKLGHI
                     MWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEKALRLIDFIEVGM
                     LMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGENSEPELIKEDLNY
                     QFVKVQTRNYKS"
     CDS             2682..3437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="Fer4_7 (E-value: 6.6e-12, bitscore: 38.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 8.7e-26, bitscore: 82.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-06, bitscore: 20.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQIINDGGEPIVFDHDCREGICGMCSLYINGHPHGPATGATTCQMYMRRFKDGDTITVE
                     PWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSVNTGAPQDANAILISKDIADEAMDAAAC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(3518..4648)
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MNKTFRKACAKLHLWLGLLSGIVVFIVCITGCMYAFKDEITDATQ
                     PWRFVAPLEKEFLPPSRLLAIADSVMGGASATAITYGERSDAAWVDYYQPEAGMSTVFI
                     NPYSGQVLKSVVNHNGDFDFFRLVLSGHRTLWLPREIGSPIVGYSVLIFLITLITGVIL
                     WWPRSWTRKALVQRLTLKRPFTFSRLNFDLHNVAGFYAALVLAVLCFTGLIFSLNWFSR
                     GVYSITSGGEELKPYVLPVSDTLQVVNRVTNPLDRLYTQLRLEEPAAKTFYFALPGQAD
                     GVYRVSVVHKRGSYYRTDNLFFDRYTLVSLKGAGPYAGKYTEASPADKFRRMNLEIHDG
                     RIWGLPGKIIMFLASLTGASLPVTGFIIWYRKRRKR"
     CDS             complement(4655..5875)
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MITMYRIYMYLLAACLLLGVTACEEEGLGNEETPFAPYVLSLGIN
                     SNGTTTYYVVTAPELMSGTINAVAKGIEQNGYRDYEQAGQTVFSIGGLGLTSATGIVRD
                     ANGYLTERGDFVFNSSLNAFTQMDGQNMIGLELPANKESGDQMTLYTVNISDVSITSQV
                     KAPVFPLNQLEWPSITGMCYSEGNVYVTYFPMNPSTFETLYTDTTFVAVYSYPDMQFKT
                     LMKDTRTGPAGSWNAFNGIFKVESGDMYIMSNSAIANGFSQSTKNAAFLRIPKGETHFD
                     DYYFDFETVSGGLKPAHIKYIGNGLVFAEVSTISPQTSADRWGDKSLKCCIIDLNNKTV
                     RDIKEIPVHNGDGGRRFAALVDGGYVYRPVTTSEGTYIYQVDPQAATAVRGAKVSTTFV
                     GGFFRLD"
     CDS             complement(5885..8302)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MNHKVLYRVALFCLFSMLSAVLMHAGEQQQQSKGIVTGRIVDQQK
                     QPYYPVAVAIEGVYIGGYTNENGVYHINDVPAGSQTIVVSGIGVKTKKVPIHVTAGKVN
                     RIPDIEIDTQAEELEEVQVIGKSEARRQQEQAYAISVLDIKKAYNSAAPLNKLLNNVSS
                     VRIREEGGMGSNYNFSLNGFSGNQVKFFLDGIPMDNFGSSFNLANISANMAERVEVYKG
                     VLPVNLGADALGGAVNIVSRKDANYLDATYSFGSFNTHKVSVNGAYTHLKTGFTVRANA
                     FYNYSDNDYKVFVPIIDLATNKKIDERWVKRFNDAYRSGGIRLETGITNKPYADYLLAG
                     IILSKNDKDVQTGATMDAVYGGVKMKSESVIPSIRYKKDDLFLDGLSLSLYGTYNSVNT
                     FNVDTIARRYNWLGESVPSTSAGEGYYTDSKIKNREWLGNGNISYVIDGHQSLILNHVV
                     SAMRRTMNDKVRPDDENNNVPQQLTKNITGLGWQIRYDRWNANVFGKMYKLYSSTYKRL
                     DEYTENARWEKVRDHKTNFGYGAAATYYILPSLQAKFSYEHAYRLPESIEMFGDGLIQQ
                     RNPDLKPESSRNLNLGLSFIQTFGAHQLSADGNFIYRYTTDFILKGVSLTSNPTTGYEN
                     LGKVLTKGVEAAVRYNYKDLFHTGAGFTYQDITDRQRYEKTKDSFVGEGITENITYKER
                     LPNIPYLFANADAGVRFHDLIWRNSVLTFDYNLNYIHSYYLSFPGLGAKSSKKVIPEQF
                     SHDLALGYSMDNGKYSVVVECTNLTNQKLYDNYRLQKPGRAFNVKLRYFLSK"
     CDS             complement(8436..9281)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MPSSVCGDPMMCQNCKKSVPNAIFHVYHRRGFHYPAQKCEENFIL
                     FLIKGEMLVNSREYAGTMLKAGEFMLQPISSKIEMLAMTDVECIYYQFNQPELFCDIRY
                     NRIMKETDPPLIPSPLPIIPELQHFLESARTYLSEKKICRDLLSLKRKELAFILGYFYS
                     DYDLASLVHPLSKYASSFECFVYQNYKKVKTVEEFAKLGGYSQTTFRRIFDNVFHEPVY
                     EWMLSRRKEEIIYELQNTEATISEICYKFGFESLPHFSNFCKKSFGTSPRSIRLKRSSE
                     "
     CDS             complement(9504..10514)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MKKILFAAVAAMAITGCSQNEEIEKAVQPVEISFNTAVSKTTRAT
                     TLVNSAFTKFTAYAYSTTGAFADATEVNALISGTEFELKESTWGSGSSVFYWPATDQVS
                     FFAFSPNTTEQFSWGAAAAKTAPTLTYTVKDAVKDQEDLVVAEAMNKQKATSGSTEAVA
                     LNFKHALTKVGFKIKGEGSGVTYTLNKIVINAKKKGVYTYGATSTTSETTLGTWTIPSD
                     VTANTAYTVEPTKALSITGADNGGTANETLVGADYTAMLIPQDLTGVTFEIYYKAEAGG
                     AILCDKTTTPEEITFADGTWTAGQSVAYVLTLKGVEKMSITGSVADSWDFTETPK"
     CDS             complement(10570..11508)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MVLLSFLVVTGCSRRDILDDYPVSGVEVRLDWSGVTEKLPEGVRI
                     IFYPKDEKGRKIDTYLSVTGGEVKVPSGHYAVVIYNYDTETVLIRGEESYETIQAYTNF
                     CKLGIAGTEKMVWGPDPLYVVNIDDLDIQNSEETLILKLKPKLVIRTYSFSIKVQGLSN
                     VSNVIGSIGGMADHYFLGKAYAMCDDYPINIDLNVKAGKIEGVFTTFGLPEAIITRLEI
                     KLPVMMNLMIIKVDNSVQEVKINITEAVQEPTGGGEGGEGEETKPPALVEVEIEDEIKV
                     DDVETPPSGGGGIGGDVGDWDDETNVELPVG"
     CDS             complement(11542..12513)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MENRICILTLFVFLFLLSGESRAMVAMPDAWIRMMIGVNQKDWSL
                     LRERVQADLHVPDREDVLMLIDYHRDDRMKCENLLRRLNGGEAYRYIMNKILPLLYVYR
                     EHSPVPIPDDKAAGVFLSTVNVLPRVKFVHPQPVVPEEGKIETPVIIEQRTVLALKNNL
                     LYDLALAPNIEVEIPLNRRWSVNAEYKCPWWLNSSREFCYQLLSGGVEGRCWLGNRKRR
                     NRLAGHFIGAYAEGGIYDFQFKGDGYQGRYYAASGLTYGYAKQIARHLSFEFSLGIGYL
                     TTEYKKYTPYEGDLVWKSSARYNFIGPTKAKVSLVWLITARR"
ORIGIN
        1 taggaaggaa agtggtgatg agcgttaccg gtatcgccct tgtcctgttt ctaacgtttc
       61 acatggcgat gaaccttgtt gcgatcatct cggctgaggg ttacaacctg gtttgtgagt
      121 tcctgggagc aaactggtat gcgttggtag ctacgctggg cctggctgcc ctcttcgtga
      181 ttcacattat ctacgctttc tggctgacaa tacagaatcg cgcagcacgt ggtagcgaac
      241 gttacgccgt agttgacaaa cctaaaaccg tggaatgggc atcacaaaac atgttggtgc
      301 tgggtatcat cgttatctta ggtttgggcc ttcacctctt taacttctgg gctaaaatgc
      361 agttacctga attggtgcac aacatgggag gagtagcaga cacaacttat gctgctgatg
      421 gtgtttatca catcatgaac actttctcta accctgtata tgtagtgctg tacctcgttt
      481 ggctgggcgc cctttggttc cacctgactc atggtttctg gagctctatg caatctttgg
      541 gctggaacaa caagatttgg atcaaccgct ggaaatgcat ctccaacatc tattcaacca
      601 tcgttgttgt atgctttgct ctggtagtag tcgtattctt cgttaaatcg ttggcatgcg
      661 gtgcttgcta aattgtaaat tgtaaatgat taaattgtaa atagcattat gactaagata
      721 gattcaaaaa ttcctgaagg ccagctcgcc gaaaaatgga gtaactataa ggctcatcaa
      781 aaacttgtta accctgccaa caaacgtcgc cttgacatta tcgttgtagg taccggactt
      841 gccggagcat ctgctgccgc ttctctgggc gaaatgggtt tcagagtatt caatttctgt
      901 attcaggatt caccccgccg tgctcactct attgcagcac agggtggtat caacgcagct
      961 aaaaactatc aaaatgatgg tgactcggtt taccgtcttt tctacgatac aatcaaaggc
     1021 ggtgactacc gtgcacgcga agccaacgtt taccgtctgg ctgaggtatc aaacgctatc
     1081 atcgaccaat gcgtagcaca gggtgtacct ttcgcacgcg attacggtgg cacacttgac
     1141 aaccgttcat tcggtggtgc acaggtatcc cgtacgttct atgcccgcgg ccagaccgga
     1201 cagcagctgt tgctgggcgc ttattcagca ttgagccgtc aggtacaaaa aggtactgtt
     1261 aaactttaca ctcgttacga aatgctcgac ctcgttgtaa ttgaaggacg tgcgcgcggt
     1321 atcattgccc gtaacctcgt aactggtgaa atcgaacgtt tcgctgctca cgctgtagtt
     1381 atcggtacag gtggttacgg aaacgcattc ttcctttcta ccaacgctat gggttccaac
     1441 ggttcagttg ccatccagtg ctataagaaa ggtgcttatt ttgccaatcc ttgtttcgct
     1501 cagattcacc cgacttgtat ccccgtacac ggtgacaagc agtctaagct gacattgatg
     1561 tctgaatcac ttcgtaacga cggtcgcatc tgggttccga agaagattga agatgccaaa
     1621 gcattgcagg caggcactaa aaagccgacc gaaattcctg atgaagaccg tgacttctat
     1681 ctggaacgcc gttacccggc attcggtaac cttgttccgc gtgacgttgc ttcacgtgca
     1741 gccaaagaac gttgtgatgc cggtttcggt gtgaacaata ccggtttggc cgtcttcctc
     1801 gatttcaaat atgctatcga tcgtctgggt gaggacgtgg ttcgtgcccg ttatggtaac
     1861 ctcttcgaca tgtacgaaga aatcactgac gagaacccgt acaagactcc gatgatgata
     1921 ttccccgcta tccactacac catgggtggt atctgggttg attatgaatt gatgacttct
     1981 atcccgggtc tgttcgctat cggtgaagcc aacttctccg accacggtgc taaccgcttg
     2041 ggtgcatctg cattgatgca gggtctggct gacggatact tcgtattgcc ttacactatc
     2101 cagaactacc tggccgatca gattcaggtt ccgcgcttct ctaccgacct gccggaattt
     2161 gctgcagccg aaaaggaagt gaaagataag atccagaaga tcaaagccgt aaacggaaaa
     2221 cactctgttg actctatcca caagaaactg ggtcacatca tgtgggactt cgtaggtatg
     2281 gcccgtacaa aagaatctct gcagaaagcc ctgacaggca ttgaagaggt gaagaaagat
     2341 ttctggacca acgttcgcat cccgggtgat gtaaacgaac tgaacgtaga actggaaaaa
     2401 gcactccgtc tgatcgactt cattgaagta ggtatgctga tggctcgcga cggtttgaac
     2461 cgtgaagaat cttgcggtgg acacttccgt accgaatacc agaccccgga aggtgaagcg
     2521 ttacgtgacg ataagaactt ctcatacgta gcttgctgga aatacaccgg tgaaaattca
     2581 gaaccggagt tgatcaaaga agatttgaac taccagttcg taaaagttca gactcgtaac
     2641 tacaagtcat aattcggcta atcaattaaa ggaaaacaaa aatggataaa aatatatcat
     2701 tcacactgaa ggtatggcgc cagaaaggcc cgaaagcaaa aggtgctttt gaaacatatc
     2761 aaatgaaaga tatcccgggc gatacgtcgt tcctcgaaat gctggatatc ctgaacgaac
     2821 agattattaa tgacggtggc gaacctatcg tattcgacca tgactgccgc gaaggtatct
     2881 gcggtatgtg ttctctttac atcaacggac acccgcacgg acctgcgaca ggtgctacta
     2941 cctgccagat gtatatgcgt cgcttcaaag atggagacac catcacagtt gaaccttggc
     3001 gttctgccgg tttcccggta atccgtgact tgatggttga ccgttcggct tatgacaaga
     3061 tcatgcaggc cggtggttac gtaagcgtaa acacaggtgc tcctcaggat gccaacgcta
     3121 tccttatctc taaggatatc gccgacgagg ctatggatgc cgctgcatgt atcggttgcg
     3181 gtgcttgtgt agctgcttgt aagaatggtt ctgccatgtt gttcgtatca gctaaggtca
     3241 gccagctgaa cctccttcca caaggaaaag tagaagcagc acgccgtgca aaagctatgc
     3301 tttctaagat ggacgaactg ggattcggta actgtacaaa cacacgtgct tgtgaagcag
     3361 agtgtccgaa gaacatttca atcagcaaca tcgctcgttt gaaccgcgat ttcatcatcg
     3421 caaaactgaa agactaagca caacttagca tttgattaat aagtaggaaa attccccacc
     3481 ggtatcggtg gggaattttt gtatatggag agcagtgtta tctcttacgg cgcttacgat
     3541 accagatgat aaagccggtc acaggaagtg aagcacccgt caggctcgca aggaacatta
     3601 taattttacc gggaagcccc cagatgcgcc cgtcatgaat ctccagattc atacgacgga
     3661 acttatcggc gggagaggcc tcggtatatt taccggcata aggaccggct cctttcaaag
     3721 aaaccagtgt ataccggtca aaaaacaaat tatcggtacg gtagtaagac cctcttttat
     3781 gtacaacact gacccggtaa acaccatcgg cttgtccggg taaagcaaaa taaaaggtct
     3841 tggcagcagg ttcttcaagc cgtagctgag tataaagtct gtccaaaggg tttgtcacac
     3901 gattgacaac ctgcaatgta tcggataccg gtaaaacgta gggcttcaac tcttcaccac
     3961 ccgaagtgat gctgtacacg cctctgctaa accaattcag gctaaatatc aatccggtaa
     4021 aacataatac ggccagcacc aatgcagcat aaaaacccgc aacattatgc aggtcgaagt
     4081 taagccttga aaaggtaaag gggcgtttca gagtcaaccg ttgcacaagt gccttgcgtg
     4141 tccagcttct gggccaccaa agtatcactc ccgttatcag ggtgatgagg aaaatcaata
     4201 cactgtaacc aacaatcgga ctcccgatct ccctggggag ccataaagtg cgatgcccgc
     4261 taagcaccaa ccggaagaaa tcgaaatcac cgttatgatt cactaccgac ttcaatacct
     4321 gtccgctata cggattgata aaaacagtac tcatccctgc ttccggctga tagtagtcca
     4381 cccaggccgc atccgatctt tcaccgtaag tgatggctgt ggccgaagct cctcccatga
     4441 cagaatccgc tatcgcaagt aagcgggaag gcggcaaaaa ctctttctcc aatggagcta
     4501 caaagcgcca aggttgtgtg gcatcggtaa tttcgtcttt aaatgcatac atgcagccgg
     4561 tgatgcagac tatgaatacc acaatacccg aaagcaatcc aagccataaa tgaagtttcg
     4621 cacaagcctt ccgaaaagtc ttattcatct cctatcaatc cagacggaag aaaccgccga
     4681 caaacgtggt tgaaacttta gctcccctga ccgcagtagc cgcctgagga tctacctgat
     4741 aaatgtaagt accctctgaa gtagtgaccg gacgataaac ataacctccg tctaccagag
     4801 cggcaaaacg ccgtccgcca tctccgttat gcaccggaat ctctttaatg tcacgtaccg
     4861 ttttattatt aagatcgata atgcagcatt tcaaactctt atctccccaa cggtcggcgg
     4921 atgtctgcgg actgatggtg ctgacctcgg caaataccag accattaccg atatatttga
     4981 tatgggcagg tttcaatcct cccgaaaccg tctcaaagtc aaaatagtag tcatcaaaat
     5041 gcgtctcacc tttagggata cgaaggaaag cagcattctt ggtactttgt gagaacccgt
     5101 tggcaatggc agaattagac atgatgtaca tatcgccgga ctctacctta aaaataccgt
     5161 taaatgcatt ccacgaaccg gcaggaccgg tacgcgtatc tttcatcaat gtcttaaact
     5221 gcatatccgg ataagagtat accgcaacaa aagtagtatc ggtatataaa gtctcaaaag
     5281 tggaagggtt catcggaaaa taagtaacgt acacattacc ttcactataa cacatacccg
     5341 tgatactcgg ccattcgagt tgattcagcg gaaataccgg agctttgacc tgagaagtga
     5401 tagaaacatc actgatattt acggtatata aggtcatttg gtccccactc tccttattag
     5461 ccggaagttc aaggccgatc atgttctgcc cgtccatttg tgtaaacgca ttcagcgaac
     5521 tgttaaagac aaagtctcca cgctccgtca gatagccgtt tgcatcacgt acaattccgg
     5581 ttgcactggt cagtcccagt ccgccaatac tgaacaccgt ttgtccggcc tgttcataat
     5641 cacgatatcc gttttgctcg atacctttgg ccaccgcatt gattgttccg gacattaatt
     5701 cgggtgcagt aaccacataa taagtggtag tcccattgga attgataccc aggctgagta
     5761 catagggagc aaaaggagtt tcctcatttc ccaatccttc ttcttcacat gccgtgacac
     5821 ccaataaaag gcaggcagca aggagataca tataaattcg atacattgta atcatcagac
     5881 ttttttattt actcaagaaa tatctcagtt tcacattaaa ggcacgcccg ggtttctgca
     5941 agcggtagtt atcatacagc ttttgattgg tcagattggt acactccaca accacactat
     6001 actttccgtt gtccattgaa taccccaatg ccagatcgtg tgagaactgt tcggggatta
     6061 cttttttaga gctttttgca cccaagcccg ggaacgaaag ataatacgaa tgaatataat
     6121 taagattata gtcaaacgtc agcacagagt ttctccaaat caaatcgtga aaacgaaccc
     6181 ctgcatcggc attagcaaac aaataaggga tgttcggcaa acgctcttta taggtaatat
     6241 tctctgtgat accttcgccg acaaagctgt ccttcgtctt ctcatatcgc tgccggtcgg
     6301 taatgtcctg gtaagtaaaa ccggctcccg tatggaacag atctttatag ttatatctga
     6361 cagcagcctc aacacccttt gtcaacacct tacccagatt ctcgtaaccg gtagtcgggt
     6421 tactggtcag gctgacccct ttcaggataa agtctgtcgt ataacgataa atgaagtttc
     6481 catcagccga aagttgatgg gccccgaaag tttgaatgaa gctcaacccc agattcaaat
     6541 tccggctgct ttccggtttt aaatccggat tccgctgctg aatcaacccg tctccaaaca
     6601 tttcgatact ttccggcaaa cgataggcat gctcgtaaga gaacttagcc tgcaaagagg
     6661 gtaagatata ataagtagcc gccgcaccgt atccgaaatt ggttttatga tcccgcactt
     6721 tttcccaacg ggcattctct gtatattcat ccaaccgctt ataggtagaa ctgtacaact
     6781 tatacatctt tccgaataca ttggcattcc aacgatcata gcggatctgc catcccaagc
     6841 ctgtgatatt cttagtcagt tgctgaggta cattgttgtt ttcatcatcc ggccgtactt
     6901 tatcattcat ggttctccgc atagcagaaa ccacatggtt cagtatcaat gattggtgac
     6961 cgtcgatcac gtaactgatg tttccgtttc ctaaccattc gcggttcttt atcttggaat
     7021 ccgtataata cccttctcct gcagaagtag acggaacgga ttctcccaac cagttgtaac
     7081 ggcgggcgat agtatccaca ttgaaagtat ttacagaatt atacgttccg taaagtgaca
     7141 gcgaaagtcc gtcaagaaac agatcgtctt tcttataacg aatagaaggg atcacagatt
     7201 cactcttcat ttttacgcca ccgtaaacgg catccatcgt agcaccagtc tgtacatctt
     7261 tatcattctt cgaaagaata atgcctgcaa gcagatagtc ggcataaggc ttattggtta
     7321 ttcccgtctc caggcggata cctcctgacc ggtaggcatc attaaagcgc tttacccacc
     7381 gctcgtctat cttcttattg gtagccagat caatgatggg cacaaacact ttataatcat
     7441 tgtcggaata gttatagaaa gcattggcac gcaccgtgaa acctgttttc agatgggtat
     7501 aggctccatt caccgagact ttatgagtat tgaaagagcc aaaagaatag gtcgcatcca
     7561 gataattggc atctttacgg ctgacgatat tcaccgctcc tcccaaggca tcggcaccca
     7621 gatttacagg taatacccct ttatatacct ctacacgctc agccatgtta gccgagatat
     7681 tagcgaggtt aaaagacgat ccgaaattat ccatcggtat tccgtccaaa aagaatttca
     7741 cctgattgcc cgaaaatccg ttcaggctga aattatagtt agaccccata ccaccttcct
     7801 cacggatacg gacactcgac acattgttca ataatttgtt gagaggtgca gcgctattat
     7861 acgctttctt gatgtcgagt accgatatgg catacgcctg ctcctgctgc cggcgagctt
     7921 cagattttcc aatcacctgt acttcttcca gctcttccgc ctgggtatcg atctctatgt
     7981 ccggaatccg gttcactttt ccggcagtca catgtatcgg caccttttta gttttcactc
     8041 ctatgcccga tacaactatc gtctgactgc ccgccggcac atcattgata tgataaactc
     8101 cattctcgtt ggtatatccg ccaatataaa caccttcaat ggcaactgca accggatagt
     8161 aaggttgctt ctgttggtcg acgattcgac ctgtcactat acctttactt tgttgttgct
     8221 gttcgccggc atgcataaga acggctgaca gcatagaaaa aagacagaat aaagctactc
     8281 tgtacaacac tttgtggttc attaatcact ctgtttaatt agtccgcaaa ggtacgtata
     8341 tcgacaccgg acgacaatca ccatatttag gtattcaccg aaactccgat acctaaatac
     8401 aatgataaaa aaaatctctc ttccagaggc ctgtctcatt cggatgaacg cttcaatcga
     8461 atgctgcgtg gcgaggtacc aaatgacttt ttacagaagt ttgagaaatg cggtaaagat
     8521 tcgaacccga atttataaca gatttcagag atggtagcct ctgtattctg aagttcgtaa
     8581 atgatctcct ctttgcggcg gctaagcatc cactcataca ccggctcatg aaaaacatta
     8641 tcgaaaatcc tcctgaatgt agtctggcta tatcctccaa gtttagcaaa ctcttcaaca
     8701 gtcttcacct tcttatagtt ctgatataca aagcactcaa acgaagaagc atattttgag
     8761 agaggatgta ccaaggaagc caggtcataa tccgaataaa aataaccgag tatgaaagca
     8821 agctctttcc gctttaatga taagagatcc cgacaaatct tcttttcgct cagataagta
     8881 cgtgcagact caagaaaatg ttgaagttcg ggaataatgg gtaagggtga gggaattaac
     8941 ggaggatcag tctccttcat gatacgatta taccggatat cacaaaacaa ttcaggttga
     9001 ttaaactgat aatagataca ttccacatcg gtcatggcca gcatttctat tttcgaactg
     9061 atgggctgaa gcataaattc tccggcttta agcattgttc cggcatactc ccggctattc
     9121 accagcattt ctcccttgat aagaaacaaa atgaaattct cctcacattt ttgtgcagga
     9181 taatggaaac cacgtctatg gtaaacatgg aaaatggcat taggaactga ctttttgcag
     9241 ttctgacaca tcatgggatc tccacaaacg gagctgggca tatatacggg tgtgtttgtt
     9301 tgtatgttta cgacaaatgt aagagaatta tttagaaaga caataaaaga aggaataaaa
     9361 aaatagccct acttgaacag ggctatcaaa tgcatcattt attataatat tatggatagt
     9421 cccatatttg aaaacaggat tcaagtttta tacttgaatc ctgaagtttt ctatttacac
     9481 aaaatgatgg acagtatcga atactactta ggagtctcag tgaaatccca gctatcagca
     9541 actgaaccgg taatagacat cttctcaacg ccttttaacg tcaatacgta agcaacactt
     9601 tgtccggcag tccaagttcc atcggcaaat gtaatttctt ccggagtagt tgttttatca
     9661 cacaatatcg caccaccagc ctcagctttg tagtaaattt cgaatgtaac gccagttaaa
     9721 tcttgaggaa taagcatggc tgtgtaatct gctccaacca aagtctcgtt cgcagtgcca
     9781 ccgttatctg ctcctgtaat agaaagtgcc ttagtaggtt cgacagtata tgctgtatta
     9841 gctgtaacat cgctaggaat agtccatgta cctaatgttg tctcactagt agtagaagta
     9901 gccccataag tatacacacc ttttttcttg gcattaataa ctattttatt taaagtgtaa
     9961 gtaacaccac ttccttctcc ttttatttta aaaccaacct tcgtcaacgc gtgtttaaaa
    10021 tttaaagcaa ccgcttctgt ggaaccactc gtagcttttt gcttattcat cgcttctgct
    10081 accaccaaat cttcctgatc tttcacagca tctttcacag tataggtcag tgtaggcgct
    10141 gttttagcag cagctgctcc ccaagaaaac tgttctgtag tgttaggtga aaaagcaaag
    10201 aaacttactt gatctgttgc cggccaatag aatacagagc taccactgcc ccatgtgctt
    10261 tcttttaatt caaattcagt tccagatatc agcgcattaa cttctgtagc atcagcaaat
    10321 gccccagtag tagaataggc atacgccgta aactttgtaa aagctgagtt cactaaagtc
    10381 gtagctcttg ttgtcttact tactgccgta ttgaaactaa tttccaccgg ctgtacagcc
    10441 ttttcaatct cttcattctg tgagcaaccc gtaattgcca ttgcagcgac tgctgcgaat
    10501 aaaatcttct tcataatagt atgttttttt aagttattaa tatttttatt tgtatgtatt
    10561 tcttttttct tatccaacag gcaactctac attcgtttcg tcgtcccaat ctcctacatc
    10621 accaccaatg ccaccacctc cacttggagg agtttccaca tcatctactt ttatttcatc
    10681 ttctatttca acttcaacca atgccggcgg ttttgtttcc tctccttctc ctccttcacc
    10741 accgccggta ggttcttgta cagcttccgt tatattaatc ttaacctcct gtaccgaatt
    10801 gtccacctta ataatcatca ggttcatcat caccggaagt tttatttcta aacgggtaat
    10861 aatagcttcc ggtaatccaa aagtggtaaa taccccttct atcttcccgg ctttcacatt
    10921 caggtcaata ttaatcggat agtcatcgca catagcataa gcttttccta aaaaataatg
    10981 atctgccatc ccaccaatac tccctatcac gtttgaaaca ttacttaatc cctgcacttt
    11041 gatactaaag gagtaagttc ttatcaccaa ttttggtttc agcttcagaa tcaatgtctc
    11101 ttcactattc tgtatatcca aatcatctat atttaccaca taaagcggat ccggtcccca
    11161 aaccatcttt tctgtacctg caatacccaa tttacaaaaa ttggtataag cctgaatggt
    11221 ttcataagat tcctctccac gaattaagac cgtttcagta tcgtaattgt aaataacaac
    11281 agcgtagtgt cccgaaggaa cttttacttc cccacctgtt accgacaaat acgtatctat
    11341 ctttctacct ttttcgtctt tcggatagaa aataatccga actccttccg gcaacttctc
    11401 cgtcactccg ctccaatcca gccgcacttc cacaccactc accggataat cgtccagaat
    11461 atcccgccgg ctgcatcccg tcaccaccag aaacgagagg agaaccatgc aaagcaacct
    11521 tgttatatct ttcattcatt atcatctcct tgctgttata agccacacca aagatacttt
    11581 tgccttggtg gggcctatga agttatagcg tgcactactt ttccaaacca agtctccctc
    11641 ataaggagtg tacttcttgt actccgtagt cagataacct atgcccaggc tgaattcaaa
    11701 cgagagatgc cgtgcaatct gctttgcata tccataagtc agccctgaag ctgcataata
    11761 tcttccttga tagccgtctc ctttaaactg gaaatcataa attccccctt cggcataagc
    11821 tccaatgaaa tgtcctgcca agcgattcct ccgcttccgg ttgcccaacc agcaacgacc
    11881 ttcaacgcct cccgaaagca attgatagca aaactcccgg ctactattga gccaccacgg
    11941 acatttatac tcggcattga ccgaccagcg tctgttcaat ggtatttcca cctctatatt
    12001 cggtgccaat gccaggtcgt atagcaggtt gtttttcagt gcaagcactg ttctctgttc
    12061 tattattact ggtgtttcta tttttccctc ttccgggacc accggctgag gatgtacgaa
    12121 tttcactcgg ggcaatacat tcaccgtact caaaaacaca ccggcagctt tatcatccgg
    12181 tatgggtaca ggtgaatgtt ctctgtatac atataaaagc ggtaagattt tattcataat
    12241 atagcggtat gcttctccac cgttcaacct gcgtaataaa ttctcacatt tcatccggtc
    12301 atcgcggtga taatcgatca acatcagcac atcctcacga tccggaacgt ggaggtcagc
    12361 ctgcactctt tcacgtaaca gcgaccaatc cttctggttt acaccaatca tcattctgat
    12421 ccaggcatcc ggcattgcta ccatggcccg gctttctccc gaaagcagaa agagaaaaac
    12481 aaaaagggtc agtatgcaga tacggttttc cataatttgt ctgtttgtgc aatacaaata
    12541 tagaagttca aatcgataca taataattta atcaaagcta aatacaagct ctgaatgctt
    12601 ctgtgaaacg attgaaagga atttgcaagt ttggcggtga agcacccccg cacttgggta
    12661 gctttccggc caatgtcggc ctctaaaagt gggtactgcc gttgcttaaa tcttcttact
    12721 taccacctga cttacttatc ccggcaagaa aatagatttg tctctacgac atacgttgtc
    12781 cgacatgggg gtgtcagacc gtccgacacc cccatgttaa acctcccgac atccccatgt
    12841 cagactatga agagtgggaa cctaatgaag aaagcttttc aaggaaagtg aagggaggtt
    12901 aaaagcaaaa gagttattgc cgatgtttag cccacttgta aaagagaaca gtaaaaaaca
    12961 gtaaaagaaa ctcaaagaga gccaatatta agaagaatat ttggataata gataagagaa
    13021 acctacattt gtacagtgat ttttttcata gtattagatt taaggttaac aaaaggttgg
    13081 agtcaggcgt gactcctttt tttttgcctt ttttatctga gtaactggta aactcctcct
    13141 gccagaaccc gaataacgcc tttcatttca agttcaaaca gaatagcact gatcttatta
    13201 atgggaatat cggcctgaac catcaatgcg tttatttgca gatcgcccag ctttccgaga
    13261 atatcgacaa ttctcagttc ctcggcagac agatccggaa agaggtttcg ctgtacggtt
    13321 tccggcttga cacttttcaa atcgctgtcc cagcccattg ctttcacaaa gtccgatgca
    13381 gactccagca aaacagcttt gttctcttgt atcaactggt tgcatccctt tgaatat
//
