LOCUS       c00018_gnlPro..        15362 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ACELJHIP_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 04:31:05
            Original ID  :: gnl|Prokka|ACELJHIP_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15362
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15362
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6042:12470]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6043..12470
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..15362
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15362
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             complement(229..1959)
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLVETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYMGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRENYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSEEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEKSYAMWTNRMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPKGEKITILKMADGKPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(1978..4404)
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLKKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETTFS
                     APGHEELGRMLEIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NAIEQGRQSMVAEGITMSRYPSSVHQFISSFSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGNSALQDLMYIMTLEFA
                     VEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRGYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKASGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLDERGEGTARLVLPEGTTGIFIWDGKEIPLKPGEQVISLSSRH"
     CDS             complement(4526..5314)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="Fer4 (E-value: 5.1e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.8e-06, bitscore: 15.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNQ
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             complement(5320..5895)
                     /locus_tag="ctg18_4"
                     /transl_table=11
                     /translation="MRFDENFNVSLSLNPKREMIKVMKKYLLASLLALLAFVGKAQEDN
                     SDIVKVGDTMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             complement(6043..6624)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="POR (E-value: 2.1e-43, bitscore: 138.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAATPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             complement(6621..8222)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_6"
                     /sec_met_domain="POR_N (E-value: 9.9e-15, bitscore: 44.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-18, bitscore:
                     56.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRIYGNFAMIQMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNFEEMKSIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             complement(8318..9364)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TINALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKQAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLRRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRI"
     CDS             9730..10347
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKTKK"
     CDS             complement(10410..12470)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="Succ_CoA_lig (E-value: 5.3e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 7.2e-22, bitscore:
                     67.8, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPETELALISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(12550..13302)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHTHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSND
                     ADRIAALEIAVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHL
                     QIFEVSATKGDGMDAWCDWLQTESAKCK"
     CDS             complement(13332..13679)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLA
                     FALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKE
                     LRMKSIVIKKE"
     CDS             complement(13692..15362)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_12"
                     /sec_met_domain="Peptidase_M22 (E-value: 7.6e-10, bitscore:
                     28.5, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLKLTSRLLLGGEVIAAKGIGGYHLICDASNERAVARLREIKQRD
                     TKPFAVMFRDLEHLQVYTATEPMEERCLVSWRRPIVLLRQRSRLASGINPGMHTLGCML
                     SYMPIHYDWFARTGIPALVMTSGNLSDLPIAITPEDAEAQLAGKVAVLLHHNRPIHNRV
                     DDSVLQVCGGQPCLIRRSRGYVPEPFFTDTNVEGIMAFGAEKVNTFALGKGETILQSQY
                     IGDLKNWETFRFYTESMERFRHLFRFNLQRLVCDLHPDYLSSQEAERISKSLSLPLLKV
                     QHHHAHAAACMLEHGLNEPVLAIVMDGTGLGDDGKVWGGEFFFCDRAKYRRLSHFEYVP
                     LPGGDKAAEEPWRMVVAYLWHYFKDEPSGIPYPADFVERIGTERIAMLERMMEKGVNTP
                     YTSSAGRLFDAVASLLGICDVSSHQAEAPVLLEQAAMGERNAYAYPVSAEGEEISFYSL
                     FEALLHDKTNEVPVSLISARFHTTLASLFVQKARLLIKRTKATQVVISGGCFQNKLLTE
                     SMRRQFIMAGVPVYIPSRIPCNDGGIAVGQLTIASVTPF"
ORIGIN
        1 tctacagaca agaggggtat aaacgttatt tacagaaaaa gttttagaaa catacgtaaa
       61 gatgcgcccc ttgcgcccta acctatcagc aacatcccta atacgggata caaaaaagtc
      121 aatgggacac ggccgtaaag tcattgagaa accatctcta ttccattgac tttaccaccg
      181 tttcccattg agatactatc gcaaaccaga cacttcaagg acggaaactc attccccgaa
      241 aagaaactta caatcccgtt cggccgccgg tctcgtccaa tcctgcggga tcatttgcca
      301 ttggtttaaa ggttgtgggc taagtacacc cttttccttt atatattgaa tcatataata
      361 acggaggtct ttatcggtcg aatgaatgat acgactcttt aactcgtctt ggggaatgcc
      421 ggcccctttc gtcaataact cacctcctcc attacctcgg taagagttaa gagctacttt
      481 atacgtttta ttctcgtcga aaggcttacc atccgccatt ttcaagatcg tgatcttctc
      541 gcccttgggt ttcgttacat ccacggtgta aatgatacca gctgcggagt caaagttaaa
      601 actgaagttg acgaatgaga cataattctc ctgtcctttc tttctctctt tcaataataa
      661 gacatgatcg tccggagatt tcatccggtt ggtccacata gcgtatgatt tctccaagaa
      721 acctttgatc tcggctcccg tcaaattcat cgtataaagc atattctcat atttgtaaag
      781 actgaacata tcgctgatcg tgatatcccc tttatctatt tttgcgtcaa aggataacgg
      841 ggcggcaaaa gagacgtccg caccagtcaa ctccaattgt aaagagtgaa taaaatcaat
      901 aaaagcggat ggcccaaagt aagcgggacg ggtcgcgata ctctccgtaa aagttcccac
      961 cttctcggag acaaaatcat tcaccgcttt gtattgcgga gcgaatttct ccataaactc
     1021 ctcgctaggc tccaacttat ccacatccgt caaaacaccc gatacttgtt tgtccaaaac
     1081 ctttccatgc tccatcttta acacgacatc aacggaaccg actacacgcc cattacttgc
     1141 cggatttatc agtaacacgg aatctccctc gatattcgcc accttaccac aataccggcg
     1201 atgatcatgc cccatcataa ccacatcgaa gcccggaatg cgctgggcaa cctccatcga
     1261 cgcatcctca cggtactggc cggacatggt acgagcctca tttcccgcat gaaagatacc
     1321 taccacaaca tccggtttct ccttctcctg aatgatcttc atccatttac gggccgtctc
     1381 ttccatatcg gcgaaataaa gaccttgcca cagagtctcc ggtaaccata caggaatggc
     1441 cggagtaatc atccccagta caacgatctt cacaccatca cgctcaaata cctcataggg
     1501 ctttaaatag ttctcccggt cggaggtacg gataatattg gcacccaaga tagggaaatc
     1561 acattgtttg atccaacgat cgaaaacggc atggccagcc tctacatcat ggttacccat
     1621 atttcccgca ttgtacccca tataattcat catggcggaa gctatatgcg tagagaccgt
     1681 atccatgaaa ttgtaataat acgccgaagg ttgtccttgc aagatgtcgc cattatccaa
     1741 tagcaaaagg ttatcgccat acgcccggcg ttcttcttgc acgaacgaat atacccgtgc
     1801 cagacttcct ccccactccc gctgctcgat aaaattatac gggaagaagt ttccatggat
     1861 atcactggtt tccactaatt tcaactttac ttccttcgtt gtcgccgaca gaccgagagc
     1921 gaccagcagc aataaggcaa ttgaataaac tcgtctcata tcaggatttt agatagatta
     1981 atgacgcgaa gataacgaaa taacctgttc gcccggtttc aacgggattt cttttccatc
     2041 ccagataaat atacccgtag taccttccgg caagaccaga cgggcggttc cctcacctct
     2101 ctcatccaat ttataagcgg cggtcacgct tccaagcgga tgtgggatcg taccggaaac
     2161 ctccttcagt tttcccaaag acggagcgat ccgtatcttc ctaaatccgg gagcatcgct
     2221 atctatcccc aacaagatcc ggtaaaactc gatattcgga ctggctcccc aagcatggca
     2281 atcagaacgg gatggctccg gcatctctgc ccatgtggtc aatcccaacg ccatctgatc
     2341 ccgccatatt tgtaagttat ccaagaactg atcccctaaa ccggaagctt tcaacgcttg
     2401 attcaagtaa taacggaaat agatcgtaca ctggatcaag ctcgtatccg ccaaggtttg
     2461 gttcatcacc tttacggcct cctctccttt cgtaacccca gtcaagatcg ccaaggcgtt
     2521 cacatgctgg gaatagccac gatgatcctg cgtatcggcg aatagattac gggcagcgtc
     2581 ccaatatttc gggcggatcg tcttacgcat ctcggtagcg atcttccggt aatgatccgc
     2641 catggcaggg aggccgatcg cttgttccat ctccaccgca aactccaagg tcattatata
     2701 catcaaatct tggagcgccg agtttccctc tttctcccgt atcggctcgc cataatcaaa
     2761 accggccgcc caatccacga agaaccaatg aggaacgtac gacaaactat aatccggctt
     2821 caaccattgc tcgtaccacg acaaaacctg acggtaagcg ggaagcaagg tcttcatgta
     2881 tgcctcatcc ccacggtaca tccaataatc gtgccccata caaatccacc agagagagaa
     2941 cgaggatata aactgatgta cgctagacgg atatcggctc atcgtaatcc cttccgccac
     3001 catggactgc cgtccttgct ctatggcatt cttcaccata taagggtctg atgtattata
     3061 catggaaatc attgcctgta tgcgtgtatc cccgaaatat tgcagttgct cgtaatacgg
     3121 gcagtccata tacgtctcat tggcgcacag acgggcggta cgccatccta tctcgagcat
     3181 acggcccagc tcctcatgtc ccggagcgga gaaagtggtc tcgttacgga aaggataggc
     3241 agagaaagtc ccatacatat cctcgatcac caaaggctcg gaagccgtct tcactttcaa
     3301 ctccacatat ctccatgtac gccaccacag ggaggtgaag agacgattat ctcccccatc
     3361 agccagtatc ttatccccgt acccgataaa ctgcttatcc gtcaactcgt cccgatgtcc
     3421 cttgccattc aacgcatacg atttagtggt cgattcctct tcttgcttat agagggcttc
     3481 cgaataaccg atatggatct cggcctcctt tcctttgctg aaggctaagg agaaataacc
     3541 cgtcgtcagg taatcattat ccagaagcaa gcggacctcc gtattcgccg ggatcgtcaa
     3601 agcttttggc cagtaaggaa atccttgcgg gcattcgatc ccttccgacc ggcggagctt
     3661 ggccagacgc tcgatccggc tgtccatcgg aggtatcggg ctaggaacca gcaaccgtcc
     3721 cgggtaatct ctcgatcctt tcgtggcacc ctccatgccc cgtacggcct tctcccattt
     3781 cctgtcgtcg taatccggtt gttcccagcc ccaaggataa gcggaggctt ccagttcctc
     3841 gcccgggcca gccacgtaat accccaatac ctgccattcg gtccaaggag catacgcctt
     3901 attacgcagg cagacccaag tggtatccgt atttaccacc gcctcatgcc ccgtattgcc
     3961 ttgcaggata aaacccgtct gatcgtaact gatctgggcg acaggtttcc gctcggcata
     4021 attccagaca acggaggcca gcgtattctt ccctttcttc agataaggag ccagatccac
     4081 cgtctcgaaa ctccagttat agatatcccc acgggccggg cccaaggata ccaatttccc
     4141 gtttacatat aatttatacc ggttatcggc ggaaacatgg acgataaacc gggaaggaac
     4201 cacctccaga tcgaacgatt tacgaaaatg atagacccca tatacattcg gggcctcacc
     4261 cgggtaggag atccaacggg ctttccatcg tccctcgaaa agagaaggat cgatcttctc
     4321 ctgattatac cctttcaggc taatctggga ggaaagggag aaggcttgaa acacaaaaag
     4381 caaaaggaat aaataggttt tcatacaaac acggtattat ttgagattaa cgatccgaac
     4441 aaaggtacaa aaaaagagaa agcgccaaaa gaacttttgc cttttgacgc tttccctcac
     4501 aatataccgg atgcccggtc ctccattaga agaatatctc cggctccctg cgcgcgctaa
     4561 agttcttatg gagcatcgcc gtgtaaggag tatcgaaagt acgtgcgccc tcgggacact
     4621 ctttcacgca ggcgcaacat ttgatacatt ggttcgggtc gctatacata ccctcgtctg
     4681 ccaaggatat cgcatgcgta ggacacacat ccacgcaata ctcacattgc gtacataaat
     4741 cgttatccgt aacaggagct tgaggagtgg aagggccttt cacccgatac gggaaattac
     4801 ctttcacctc caaggcggac aagcattcca cgcaggaaac cttctccagc tcctcgataa
     4861 tctttttccc gaattccgta gcctgattaa gatccgactc gtccggacgc ccctcggcaa
     4921 tgggcatccc cttgcggctg aaagaatgct cgccgataaa cgctccggca gccacaggta
     4981 cgaacccctg ctccgacact aaatcacaga gctctttcaa ggcatcctca taatcccggt
     5041 tcccatacag taccacgggg actaccggcg catggtgggc agaacggaac atgcgaaaac
     5101 gttccatggc agtctccgcc acacggccac cgtatacagg agcggctata atcgtcagct
     5161 catcatcaat atactcttcc atatccagac tctcacaagt gacatcagac tcggacatcg
     5221 aagtggcacc cattccttcc gctatcgcgt aaacgatctt ggcggacgtg tgtgtcggag
     5281 aaaaataaat taaatgtatg ttactatatt tcatgattct tattttaacg caccctctat
     5341 tttagtcatt aactcagcaa attcctcatc ggtatagcct ttgctcgtat aaatgatctt
     5401 cccgtctttt ccgaccaaat agccacgagg gatcaagttc ttggcgaaag cgccgaaaat
     5461 agcccggtcc ttatcgggat acaaaggaaa atcgaagcct tttttctcgt tatatttctg
     5521 tagatcggca tcggaatgct cacgcccgat caccaagaga acgaagtcct tgttgttctt
     5581 gtatttcggc cagagggttt gttggacagc ggccaattct ttttggcagg gaggacacca
     5641 agtggcgaag aaattcacga ggatcacttt tccctttaac gaagcggact gcaacttact
     5701 cccgttgtcg gaaacaatcg taaatgacgg catggtatca ccgaccttca cgatatcgga
     5761 attatcctcc tgagctttgc ctacgaaagc caataacgct agtaaactag ccaataaata
     5821 cttcttcata accttaatca tttctcgttt aggattcagc gacaaagata cattaaaatt
     5881 ctcatcaaac cgcataattc taaggcttac gaaagttcta cgatgctgta cctacccctc
     5941 gacagctctt ctaaaagttc tagggggtta gatgttaaaa aaaacgtacg tgaaacccgg
     6001 agatgtcacg tacgctgata ccatgcaaac ccggagaaag atttaccgca gactttgcgc
     6061 taagtcataa ccggctttca acgcctttag gttcatatta actatatcct cgcccttacg
     6121 accgaatatc tgacggattc ccgcctcgat cttatcatac tcgatcccga taaatggggt
     6181 agctgccccc aacatcacga tattggcggc acggacagaa cccgcttcct tggcgatctc
     6241 ctccacgtcc aatacgacct tgtgagggag cttgtccaac tcggcgttca ctttctcgat
     6301 ctccggatag ttcgggatgt tcacgaacgg acgggagttc gtcaccagcc aaccctcttt
     6361 cttcaggtaa ggcagataac gcaagctctc catcggttcc aaggagatga tcaaatcggc
     6421 gtggcccttc gggatcaagt ccgaggcgat cggctcgtcg gaaagacgca ggttagactg
     6481 cacgtctcca ccccgttgac tcataccgtg tacttccgct tgcttcatat acagaccttc
     6541 ttttaaggcg gcttctccaa taacggcggc gatagaaagg ataccctgtc ctcctacacc
     6601 tgatagtata atatctgttt tcatttcttg cttgcttttt tctttctggt taatgtctgg
     6661 atacactcac ggcgggggat caatacggat acgcccttgt actcgatttc ctcacggatg
     6721 atagacttca tctcctcgaa gttctttttt aaaggaacca tcacacggat gtgagccggg
     6781 tccacaccga taccggcgca gatagactcc agacgtcctg ttccggcgga atcctgccct
     6841 ccggtcatgg ccgttgtctc attatcggag ataacgatgg tgatattcgt gttctcgttc
     6901 acgcaatcca gcaaaccagt cataccggaa tgggtaaacg tagaatcgcc gatcacggag
     6961 atagccggga atacacccgc gtcggaagcg cccttcgcca tcgtgatgga ggcgcccata
     7021 tcgatacaag aatcgatcgc acggaaagga ggcaaagctc ccaaggtata acagccgata
     7081 tcgccaaaca ccttagccgt accgttatac tcggcgatca cctcgttcaa ggcctcatac
     7141 atatcccggt gtccacaacc ttggcacaag gcgggcggac gttgctcaac cacctcgggg
     7201 atcgcgtaat agctctggat ctccttaccc aaggctttgc ctaccgcgtc tggcgtaagc
     7261 tcgccgtcac gctgaagcgt accgtccaga cggccatgaa ccgtcacgcc tttcgccaag
     7321 aaacctttta attgctcttc aacgaccgga tatccctctt ccaacaccaa gatctcctta
     7381 cactcgccaa cgatcttctc cacttgcttt ctcggaagcg gatactggga gatcttcaat
     7441 acgggatgct cgaaaccgtc cggataattc tcggaaagat aattgaaagc gatacccgtc
     7501 gtgatgatac ccaagtcttt attcggggca tcgaaatact tattatatgc ggaattctcg
     7561 gaagcttccg tgaaagcctc ttgagacgcc agcaaactct tgaaacgttt acgggccaat
     7621 gccgggagta agataaaacg ttgacgaccg tcttccggac aattcatccg gttctccggc
     7681 ttcaacgggc tggttacgac accggcacga gaatgcgcca tacgggtcgt tacacgcagc
     7741 aagataggat accctaattt ctcggataac tcgaatccat gatataccat atcataagcc
     7801 tcttgctggc tggatggctc aaacatctgg atcatggcga aattgccata aatacggttg
     7861 tcttgctcat tctgggaaga gtgcatggat gggtcgtcgg ccgtaaggat gatcatacct
     7921 ccgttgatac cgctcatagc ggcgttcata aagcaatcgg cggctacatt caaacccacg
     7981 tgcttcatgc agcaaagcgc acgtttaccg gcatagcaca tacccaaagc ggcttccatg
     8041 gcggttttct cattcgcgct ccagcgacaa tggatacctc tttccttcgt taccggagaa
     8101 ccttggatat attctgtgat ttcagtagaa ggggttcccg ggtatgcgta taccccggag
     8161 attccagcgt ctatagcggc ttgcgctatg gcctcgtccc ccaaaaataa atgtttttcc
     8221 atgtgtatct gttttcttaa tattgactat tcacactatt tagccgccaa aggtaatgaa
     8281 aaatgttcaa tttagaatga gagacttatg atttatacta gatccggcgc ctattcaact
     8341 ccgcccgata ccggttggca ttgcggttat gctccgccaa cgtcacggcg aaattatgcc
     8401 gtcccgagaa atcctcctta gcgcacatgt ataagtattt atgtttcgta tgattcaata
     8461 cgctattcaa gcccttgata gtaggaatcc gtagaggacc gggaggtagg cccgcatatt
     8521 tataggtatt atagggagaa tctatttcca aatgctcaaa taagatacgt cgcaaagaaa
     8581 aatcccccac cgcgaacttt acggtagggt ctgcctgtaa aggaatacca gcatgaaggc
     8641 ggttgatata aaggcccgcc acgattggat attcgtccga tgccgccgtc tcctcttcta
     8701 cgatagaagc caagatagat acctcgactg gagtaagccc gatctcctct gcctgtttca
     8761 atcgttccgg tgtccagaaa gcgtcatatt cacgcttcat gcgacgtata aatttatccg
     8821 cggatatatt ccaataaatc tcataggtat taggaatgaa gagggcattg atcgtttccg
     8881 gggtaaaacc taaagagtcg caatacacag aatcattcaa tagacgcagg agattttcct
     8941 tcccgaacat caattgatca cttatacgtt ccgccaaatc ttccttgaaa cggatattat
     9001 taaaagtaac ccgggccgct acttgatgtc ctctccgcaa atcattcaat aaggttaaat
     9061 tactcatgcc gggcttcacg gcgtatcgac cggtacgcat ggacgcagga tacttcaaca
     9121 atccactcaa ttgcttaaag ctaccgatac ggagacagtt cgccgaatcc ctcaactgcc
     9181 ggcaaagatc atcaaaatcc tttttatcat ctatatagac atagaccgtc ttatccggct
     9241 taaaattcgg agcccaagcc aaacggtaca cccaaaagcc tccaccgcct atcaaaacaa
     9301 cgagaatcgc tatcaaggcg ataattatcg ggcgcctcga taaaatttgt ttgttcaaat
     9361 ccatgaataa tctattgaat atcagaataa ggcacaaaag tagtatcttt tttcgaaaaa
     9421 aatgatgtgc aaagccttgt ttatttaaaa ttatagttct acctttgcat cgcaattcta
     9481 aggaagaagc acagaacaca caaggaagtg tgggtgagtg gctgaaacca ccagtttgct
     9541 aaactgacgt actcgtaagg gtaccggggg ttcgaatccc cccgcttccg caaagagcca
     9601 actaataaat ttattagttg gtttttttgt ttttaagcca accgaattaa agtgtttcat
     9661 atatttgtca tatttgaact tatcgtaagt cgatctgtta ttaaaaggag ataattaaat
     9721 atatacatta tgacaattgc ttttatccga acatataata ataagcaaaa ctccgaggtc
     9781 caagaagctg tgatccggga atttgccgaa tctcagaaga tagagatcgg gaagtgggct
     9841 aaagaggtgg gaaatagtcc tcgtgcgaac cgcagactgg aaagtattgt caaatcttta
     9901 agtcccgggg atgagatact tgtgtccgat atatcccgtg tgagccgtaa gatgatcgag
     9961 atcatccata tcattttgct ttgtatagag cgaaaggtaa cgcttcgtag cgtaagcgac
    10021 ggatatgtgt tcgaggataa tatcgacagt aagactttgg cctttacctt cggtctggtc
    10081 tccgagatcg agcgaaagct ggtctctatc cgtacgaagg aagcccttgc cttgatcaga
    10141 agtaaaggtg tggtgctggg ccgtccgaaa ggtagtcaac aaatgggacg cttggagcct
    10201 tataaggaac aaatcgagaa agacttgaaa gacccgagct tgacttacgc ccagatagcg
    10261 gagaaataca atgtatcgct aagtagcttc aaacgctttc tgaaagagta tcttcccgat
    10321 aagaaaaaga agaagactaa aaaataagaa aagctccttt cacctctgct aagtatatta
    10381 gcattcagta gtgaaaggag cttgtttttt tatttctcta tacggatacg ggcgtctaca
    10441 gcgaacaagc ctctatccgt agccaccaac ggatttatat ccatttcctt tatctcgctg
    10501 gcaaaacgca ataaggtaga gaggcgaacg ataatgtccg catattgttg ctcgtcgata
    10561 cccttttgcc cacgtgtacc tttaatgatc ggataccctc tcaaagaacg aatcattgaa
    10621 taagtctcat cgtatgacaa cggagccaaa ccataagaca catctttcaa tacctccacg
    10681 aagattccac ccaacccgca aagtaccaca tggccgaaac gatcctcata tttagctccc
    10741 aagaataatt cctgtccttt caacatcggt tgtaccatga tgcccgtaac acccggcaga
    10801 cgcatcatac gttcatactc gaacaataaa tgctcttctc cacggatatt caaggccaca
    10861 ccaccgatat cgctcttatg cacaggccct acaaccttgg ctaccaccgg atatttcacc
    10921 ttcttggcaa aagccagcaa cgcatcccta tcatccgaag catattcctc cactaacggg
    10981 atattagcgg cacgcaacaa tgtacgcact tcctccggat ttaaataacc gctacccggc
    11041 aaccgatcta tgatacgacg aacttccggt acatccacgc catatagctg gatatccgtg
    11101 ctcatcggtt tcggcgtatt gatcacccgt gaaagggcag tacccaatgt cacctcgtcc
    11161 gagaagttca catggccttt cttgacaaag ctcttcactt ccggtccggc cgttacgata
    11221 gacggtaata tcgggaagat cggcttcttg cactcttcca tctttttatg aagtacctcg
    11281 taggtatcat aaagttttac caaaccggga ctaccgaaga tgaccatcat caaatccaca
    11341 ttatcgaaac gattctcaca gaaatcgatg gctgtagcca aatgttccgg tgtccccgta
    11401 ccgataatat caatcggatt accgacagcg gcacccggat acagtttgga tttcaactca
    11461 tcagcgatag ggccttccaa actaggaaca ttcaaacgcc ccttggataa agcgtccgcc
    11521 agcattaccg caggccctcc ggcatgtgtc acgatcgcac aattcttccc tttcacgtct
    11581 ttcaaggtaa agatactcgc cacggtagtc aattcctcac ggctaaaaca acgcacgata
    11641 cccgccttac ggaacaaagc ctccacagca gagtccgaac tagcgatagc gcccgtatgc
    11701 gaagaggcag ctcgctttcc cgactccgta cttcccgcct tgatagcggc gatcttgcat
    11761 cccttacgta tcaaggaaga cgcatgatac aacaatttat ccggttgctt gatttgctcg
    11821 atatacaaca tcttgatctt ggaatccaat accggatcaa agttccgatc catatattca
    11881 aggatatcct ctactccatt ctgcttggag tttccaaccg accaaacaga agagaaacgc
    11941 agcccttttg tcagcgccga ctcgataatg aacaaggccg taccgccgga gctagagatg
    12001 aaatccacgc catcgggatg gaattccggt atcggttgcg taaacacgcc atgataattc
    12061 atattcatca acccgataca gttcgggccg atcaaggagg ctcccgcctc attcacgaca
    12121 tccagcatct gttgctccaa gataccgccc tcgtgtgtct cctcgccgaa accggctgag
    12181 atcacgataa aagcttttac ccccttttgc cgggccagca cttccatcac ctcggggcac
    12241 gatttactcg gaatcgagat gagcgccaac tccgtctccg ggatatcatg tacagaagga
    12301 taagacttga cgccttgcac gtctgtctcc ttggcgttta ccacacataa ttctccttta
    12361 tattttccat ccaacaggtt tcgcacgata cgaccgcccg gtttatgtac gttgttggaa
    12421 cctcccacca ctacgatgct ttgaggatta atcaattctc ggttaatcat aacattttga
    12481 ttagttagat tcaatgaatg ggagcaaata tagttttttt ctccatttat tcattaaaac
    12541 ccggggtatt tatttacact ttgcactctc tgtctgcaac cagtcacacc atgcatccat
    12601 cccgtctcct ttcgtggcgg atacctcgaa tatctggaga tggtgattta ccttcaaggc
    12661 gttttcccga agcacttcca cctttgtatt cagataagga gccagatcaa tcttgttgat
    12721 tacgcagata tctgcctcct gaaagatatg tgggtatttc aacggtttat catctccctc
    12781 cgtcgtactc acgataacga ctttcttgga ctctccgaga tcgaacatgg ccggacagac
    12841 cagattgccg acattctcta taaaaagtat cgctccctcc ttcggattca gatgcttaac
    12901 agcatgattg accatgtcgg cttccaaatg acagccggta ccggtattta cctgaaacac
    12961 ggcaatctcc aacgccgcta tacggtcggc atcgtttgag gtttgttgat cgccttctat
    13021 cacatagatc ggtcgcttcg ctttcaaacg gcggatcgtc tcttccagca aagttgtctt
    13081 accggatccg ggcgaactca tcaagttcag gcagaacagg ttcttagcct cgaaatatcc
    13141 ccggtttcgc tccgccaata agttgttacg ttgaagtata tcttgttcca gattgattac
    13201 gatcccttca tcaggatggt gatgatgttc atggccatga gaatgctcat gcgtatgatc
    13261 gtgatggtga tgatgctctc cgcatccgca agttccgcac atagtattta agtttttatt
    13321 tcattaatat atcattcctt tttaataaca atcgacttca tccgaagttc cttcccttta
    13381 aggattttaa ctaaatagga gccacaatgg ggacaagggg aaaacaaggc gttcattggg
    13441 aaaatggtct cacagtcgct acactgtcct tccccctcaa tataatgacg gataatccgg
    13501 gccttttcca gcttgctacc ttttatggcg ctatccaatg cgaacgctaa ggtttggatc
    13561 tctacgccgg acaaatgtcc tatctctaac tccaactctt cgaccaccga ggctccccgg
    13621 ttatccgctt gttcctcgac cagctccacg atactacggg ctatagacaa ctcatgcata
    13681 tctgatctct tttaaaaggg agtcaccgag gcgatcgtta attgccccac ggctatcccc
    13741 ccatcgttac aaggtatacg agacggaata tagacgggga ccccagccat gatgaactgt
    13801 ctcctcatcg actccgtcaa taatttattc tggaaacatc ctcccgagat aaccacttgt
    13861 gtcgctttcg tccgtttaat caacaagcgg gctttctgca caaacaagga agccaatgtc
    13921 gtatggaaac gggcggatat caagctcacc gggacctcgt tcgtcttatc atgcaataat
    13981 gcctcaaaca aagaataaaa agagatttcc tctccctccg ccgagactgg atacgcataa
    14041 gcgttcctct ctcccatcgc cgcctgctcc aataagaccg gagcctccgc ttggtggctg
    14101 gagacatcgc aaatccccaa taaagaagct accgcatcaa acagccggcc agcgctggat
    14161 gtatagggtg tattcacacc tttctccatc attcgttcaa gcatagcgat cctttccgtg
    14221 cctatgcgtt ccacgaaatc ggccggataa ggaatacccg acggttcgtc cttgaaataa
    14281 tgccacaaat aggcgacaac cattcgccat ggctcctcag ccgccttgtc gcctcccggt
    14341 aacgggacat actcaaaatg ggaaaggcga cggtatttcg ctcggtcaca aaagaagaac
    14401 tcgcctcccc aaaccttacc atcatcaccc agacctgtcc catccatcac gatagcgaga
    14461 accggctcat tcaatccatg ctccaacata caagcagcgg catgagcatg atgatgttgt
    14521 acctttaata aaggtaagga aagagatttc gagatacgtt ccgcctcttg gctggaaaga
    14581 taatccggat gcagatcaca aaccaatcgc tggagattga aacgaaacaa atgacgaaac
    14641 cgctccatag attccgtata gaaccggaaa gtctcccagt tctttaagtc gccaatatat
    14701 tgactttgca ggatcgtctc tccttttccc aaagcgaacg tgttcacttt ctccgcaccg
    14761 aaagccatga tcccttccac atttgtatcc gtgaaaaagg gttccggcac atagcctcgg
    14821 gaacgacgga tcaagcaggg ttgtcctccg cagacctgca acacagaatc atctacccgg
    14881 ttatggatcg ggcgattatg atgcaagagg accgctacct ttcccgctaa ttgcgcctcc
    14941 gcatcctccg gggtgatcgc tattggcaaa tcgcttagat tcccgctggt cattaccaac
    15001 gcaggtatcc ctgtacgagc aaaccaatcg taatgaatcg gcatataaga caacatacat
    15061 cctagcgtat gcatgcccgg attgattccg gaagctaacc ggctccgttg cctcagcagc
    15121 acgatcggac ggcgccaaga gacgaggcat cgctcctcca tcggttccgt agccgtatag
    15181 acctgcaaat gttccaaatc acggaacata acagcgaatg gtttggtatc ccgctgcttt
    15241 atctctcgca gacgggcaac cgctctctcg ttcgaggcat cacaaatcaa atgatagcct
    15301 ccgattcctt tagccgcaat aacctctcca ccaagcaata agcgagaggt aagtttcaat
    15361 aa
//
