LOCUS       c00010_gnlPro..        15355 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMJJPEIB_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:08:20
            Original ID  :: gnl|Prokka|LMJJPEIB_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7855
            Orig. end    :: 23210
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15355
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17855:22706]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14851
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15355
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15355
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(1160..1327)
                     /locus_tag="ctg10_11"
                     /transl_table=11
                     /translation="LDIDNHIIPFAYFLISLVATIRTATMLIGGHDDLAAEGFNRILYP
                     DIVGSYANGV"
     CDS             complement(1285..1494)
                     /locus_tag="ctg10_12"
                     /transl_table=11
                     /translation="LFLLSTTFGELGLNRELSKSSSERKGFTNVAICVFASAKQVLIVW
                     ICSGWIKGSSPWILTITSYPSPIF"
     CDS             1502..1792
                     /locus_tag="ctg10_13"
                     /transl_table=11
                     /translation="MYFSRSIIPYIRGKKYTEWLPSHTFYKHIGLYAYRAQVLKEITQL
                     PQSALELAESLEQLRWLENGYKIKVGITEQETIGIDTPEDMEKALAFLANR"
     CDS             complement(1809..3533)
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MTKNERSLQWVIAGIFFVVCFAFFQWIYPNHLFFKEQMRIFLYTT
                     DYFISFWDEPAWLSCYVGNFLIQFFHLTVIGPLIVTCVLLLLWYYSMRVLRKFGNGNMV
                     SIYALFPVALEWGLICRLSYSIASTLTLIFVLWLFLGYIRIKNKRTSVWVAFILLPIIY
                     SMVGSRLFVFSLMVIFYEGAKNRKRWWFWLSLLLSSYLYPLFMRHFYGLSIEEAYKYSH
                     VDGLSVYFPALALILEIFALEIKGIRRIRLNRHSLLITFLVVFGFFSFVIAGTNRKREK
                     VLAVDQAIYRGDWERVLDLSAGFDSPDILVSYYRNIAFSKKNELPQNLMDHYQRGADAL
                     FLPIDLRSSILPVFFSNEVYYQLGDMDMARHRAIEGILFSPKQRSVRQIKRLVEIDMRR
                     GDIEEARKYLNLLDATLFYHSWARSKEEQLKGEETLSMEKRLPRKSDWEREHDILMSIS
                     DYPGVLSSLVAEYPENKQALDYLLCYYLLNENLNSFKNTFDTYYKGKFEVVPRLYEEAL
                     VQVLSKSSDEEVAGYQIPQDVIENYQDYIHCKSGRKAKEELRERYSSTYWYYSDYIH"
     CDS             complement(3550..3735)
                     /locus_tag="ctg10_15"
                     /transl_table=11
                     /translation="LVDKGTFLYILARLLEKQDVLIMILFVYLYLFKTFCLFALFCIQK
                     IDEEIDFFYIEEIGRL"
     CDS             complement(3782..5683)
                     /locus_tag="ctg10_16"
                     /transl_table=11
                     /translation="MDKNTLIGFLLIGVVLFAFSWFNRPTPEQLEAQRRYQDSIAKIEY
                     AQQLELQKQENKSALVEDSLENLPDSVRAQRLQQSFGVFGDAMVGTEDYTTLQNDVVEL
                     RISNKGGRICYARLKEYDTYNDEPLVLFDEKESNFNFTLVTATNRVVNTSDLYFTPVKG
                     NDPNSVIMRLNTGEGSHLDFTYTLKPDDYMVQYQILGTGLNGVLAPSTNALDLLWEQDI
                     RQQEKGRKFEDRYVTLNYKFMADDVEHLSESKSDSKQIPNRLKWIGYKDMFFSTVLISQ
                     EGFEATTLDSKAIPEGDVLKQFKTTASVPFDLQGKEATNLSFYFGPNKFALLKSFDKGV
                     SAEQQLDLEKLVPLGWGIFRWVNQYFVIPLFDFLGKFIHNYGILILLMTIIVKIILFPL
                     TYKSYMSSAKMRVLRPQVEEINAKYPGQDKAMERQKATMELYSRAGASPMSGCLPMLLQ
                     MPILIALFMFFPSAIELRHQSFLWAHDLSTYDAIFSWNKYIPIITPYFGNHISLFCLLM
                     TITNIFYTKYNMEMTNTGQQQMPGMKAMMYMMPLMFLVFFNQYASGLTYYYFISTLITI
                     VQTLIFRYTINEDKLLAKLEANKRKPMKKSGFMKRLEEAQRAQQETLRKQQEAKKKR"
     CDS             complement(5694..7115)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_17"
                     /sec_met_domain="GATase (E-value: 7.3e-55, bitscore: 176.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTVDGHEADLDLGHYERFLNVQTTRANNITTGRIYQSVINKERKG
                     DYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQLKWE
                     LGKNCLCVHLTYVPYIAAAKEYKTKPTQHSVKQLQELGIQPDVLVLRTEHELNANLLRK
                     VALFCNVAEDSVIQSIDVPTIYEVPLVLQRQKMDEVVLRKVGMEVGPTPELKPWKEFLA
                     LKSTATDTVKIGLVGKYVELQDAYKSIDESLLQAAIYNHHKLDLHLFHSEKLNNENAAE
                     QLKDMDGILIAPGFGQRGIEGKFAAIKYAREHDVPCLGICLGMQCMVIEFARDVLGLAD
                     ANSTEMEPNTAHKVIDLMEEQKNVTNMGGSMRLGAYDCTLKEGSKVLEAYGKEHIQERH
                     RHRFEFNNEYKKQYEAAGMMCTGENPETNLVEVVEIPALKWFVGVQYHPEYNSTVVNPN
                     PLFLSFVKAAIENKK"
     CDS             complement(7250..7372)
                     /locus_tag="ctg10_18"
                     /transl_table=11
                     /translation="MKIANFAVSKCRCAIKKITKILLSWQIQSTFSLQAAWSLP"
     CDS             7719..9263
                     /locus_tag="ctg10_19"
                     /transl_table=11
                     /translation="MMMKRHGVYALLLLSLIGGSAYSQENQLVTGTIVQRPAQQVVSDD
                     TIPAINLSEEELDNIVDIRKQFEKQNKTYSEPLAPSTNLLRFLKKDELEISDEAMYWAR
                     LVRDASTIFDNTMTFRDTVIVNPLFMPIVFRGDYLPENLIFYNFDSLKERTPYDNLYRA
                     DSIFKDLERNKQFEEMAYKYVQNNYPTYFRYSERDLPNEVIKPKFIKKNIYEDLPIKVE
                     ADANFEDVDAPARFIPERRYWISAFESAIQFSQNYVSENWYKGGSSNLNLFTKNNLKYD
                     YKKDKVQVTNELEFKASVYTAPKDTLRNYKIGDDVFRIHSNVGYQAFNKWYYTFDAEFK
                     TQFFTNYQENERIKQAAFLAPFSINFGLGMKYELEKQFTDKHKKIKFSTNLAPISYTYM
                     YTTQEIDYSRHGFKKNEETGEFNNKLSQIGSTIRADLAFDFNRNVSWQSRLYFFTTYGD
                     HTIGEFENTLVLAISRFFSTRIYFHLRYDDGVEKTEDNKSYFQLNELLSFGFNYKW"
     CDS             complement(9382..9507)
                     /locus_tag="ctg10_20"
                     /transl_table=11
                     /translation="MILSFFSDAEHIDCAWHPEHADCWVMRTKTVSPSIFSTNPV"
     CDS             9575..9781
                     /locus_tag="ctg10_21"
                     /transl_table=11
                     /translation="MGLQAVLLAFVIPLVIVVGAIVIGTNLQWDETTSGLTGLSLLLPY
                     YCILYLMRDKLKRRFIFTLKKLN"
     CDS             10001..10723
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 36.5; E-value:
                     1.8e-11)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_22"
                     /sec_met_domain="Fer4_7 (E-value: 8.3e-12, bitscore: 36.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.6e-11, bitscore: 34.7,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.2e-09, bitscore: 27.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.7e-06, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LLCPVGGGPVMAKVATILGKEAGTAEPMVAVVRCNGTCQARPRTN
                     SYDGTKSCAIASTLYGGETNCSFGCLGYGDCVNACAFDAIHINPATGIAEVDEEKCTSC
                     GACVKACPKNIIELRKKGPKSRRIYVSCVNKDKGAAARKACANACIGCGKCAKECPFEA
                     ITVTNNVAYIDYTKCRLCRKCVAVCPTGAIHELNFPPRKEAAPAPKAETVKPAPKAEAT
                     VKPEAAPKATSEEKTNLN"
     CDS             10873..12066
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_23"
                     /sec_met_domain="Fer4_10 (E-value: 1.7e-09, bitscore: 28.7,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 5.6e-17, bitscore: 52.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.4e-50, bitscore:
                     161.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.2e-14, bitscore: 45.1,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-05, bitscore: 15.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VVKKGDLVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGY
                     KRPAIYIDVEGDEWEETIDRSETLVKECTLSSKEIVDKIAASGIVGLGGATFPTQVKLM
                     PPPGNKAEIVIINAVECEPYLTSDHSLMLEKGEQILVGVTILMKAVNVNKAVIGIENNK
                     PDAIAHLQKLAVNYKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNV
                     GTAYAVYEAVQKNKPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKI
                     IGGGPMMGKALISAEVPVCKGSSGVLLLTTEESVRKPIRDCIRCAKCVGVCPMGLNPTL
                     LMNATEFQNWELAEKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
     CDS             12079..13047
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_24"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.3e-116,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             13080..13664
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_25"
                     /sec_met_domain="FMN_bind (E-value: 1e-25, bitscore: 81.1,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             complement(13552..14154)
                     /locus_tag="ctg10_26"
                     /transl_table=11
                     /translation="LNNLPVPKNSRQAPSSVRAIVKPSPIPIPSKADGTTPFFAAKASA
                     RPSTIQFTTINGINNPKLAYKAGTNASMHICTTVTNVAITTIYPGIRTKSGITFFKAEI
                     TIFEQINTNIVANPILMPLMAEEVVPKVGHIPNSNTNVGFSVMIPFINIFRLLIVLSSL
                     FICYQLKWHPLVRLRQRMRYTHGSRHRGTHGWRLSLP"
     CDS             14279..14851
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_27"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.1e-65, bitscore:
                     210.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALIIFAGIREQLAMTHVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             14865..15353
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_28"
                     /sec_met_domain="Epimerase (E-value: 4.2e-34, bitscore:
                     108.9, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTRMKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIE
                     VLDGIEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYY
                     RNNIVTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQ
                     "
ORIGIN
        1 ataagttact aaaagccttg gtccgcatcg tcggtactta taccgccgtc tgcctagtac
       61 ttatcttttt atggctacaa atcgtgactc cgttcatctg taaacatttg cccggcatcc
      121 aaggaagtct aatctccttg atcttaatcc tagctctgat ctccccgatg ttgcgggcga
      181 tcatgatgaa aaagaatcat tccgtggagt tccagcaatt atggaacgat aataaatata
      241 accggggtcc cctagtatca ctcgtgatcc tcagaatcct gctctgtatc ggtctcgtca
      301 tgcttcctgt cgcacggtta ttgaatgctg cgctaggaat tatgctggcg gtcgcctccg
      361 ctgttatcgt attaatgata ttctccaaac ggctaaagag gcagtcgatc ttgatggaac
      421 ggcatttttt cagtaacctt gtagcgagag aaatggagca agagcgaaaa gccccgatta
      481 accagcgttt cgcgaaccac ttattagaac gagatctcca tttagcagat ttcgaggtga
      541 agcagaattc ccccagtatg ggaaaaagcc tgaaagaatt aaacttcagg caaaagtgca
      601 acgtaaatat cgtaacgatt atccggggag agaagcgaat caacataccg ggaggagacg
      661 agcggctcta cccgttcgat aaactggtag tagttggcgc agatgatgat ctggagcact
      721 ttaggaaata tctggaggaa cgctacaaga aatcatacgc cgagcaatcg aacacaagaa
      781 aggaagagat gaatatggag caaatcatta tctcggaagg ttcccgattg atcggccgct
      841 ccatcataga gtccggtatc cgtgataaag ccgcttgctt ggtaatcggt atcgaacgtg
      901 gaagtagctc gatcaagaat ccgcctccta gtacggtttt cgaggaagga gatatcgtat
      961 ggatcgtagg cgaacgggat aagttgatcc agttaagcga aggaaaagta gtaaccagtt
     1021 aacaaaatga tatagaatga tgaagtttat aggaattatt ccggcgagat acgcctctac
     1081 ccgttttccg gggaagccat tagcggatat gaacggaaag cccatgatac aacgtgtata
     1141 tgagcaagta aaggatgtct tagactccgt ttgcgtagct accgacgata tccggataga
     1201 gaatgcggtt aaagccttcg gcggccaagt cgtcatgacc tccgatcaac atcgtagcgg
     1261 tacggatcgt tgctacgagg cttatcagaa aataggcgaa gggtatgatg tgattgtcaa
     1321 tatccaaggt gacgagcctt ttatccatcc cgagcaaatc cagacgatca aaacctgctt
     1381 cgccgacgca aacacgcaaa tagcgacatt ggtaaagcct ttccgttcgg acgatgattt
     1441 cgagagttcc ctattcaatc ccaattcccc gaaagtcgta ctcaacaaaa acaacgaggc
     1501 tatgtatttc agtcgatcta ttattcctta tatccggggc aagaaatata cggaatggtt
     1561 gccgagtcat accttttaca aacatatcgg gttatatgcc tatcgtgcgc aagtgctgaa
     1621 agaaatcacc caattacctc aatccgcttt agaactggcg gaaagccttg agcaattacg
     1681 ctggttggaa aacggatata aaatcaaggt cggcatcaca gagcaagaaa cgatcggtat
     1741 agatacaccg gaggacatgg agaaagcctt agccttcctt gcgaaccgct gatcacttac
     1801 actattattc aatgaatata gtcagagtag taccaatagg tggaggaata acgttctcgt
     1861 aattcctcct ttgcttttct acccgattta caatggatgt aatcttggta attctcgata
     1921 acatcttgag gtatctgata accggccacc tcctcgtccg agcttttaga taagacttgt
     1981 accaaagcct cctcgtacaa acggggtaca acctcaaatt ttcctttata ataagtatcg
     2041 aacgtattct taaaactatt caaattctcg ttcagtaaat aatagcacaa caaataatcc
     2101 aatgcctgtt tattttccgg atattccgcc accaaacttg acagtacgcc cggataatcg
     2161 gatatggaca ttagtatgtc gtgctctcgc tcccaatcac ttttcctcgg caaacgtttc
     2221 tccatcgaca aggtctcctc acccttcaac tgttcctcct tcgaccttgc ccatgagtga
     2281 taaaataacg tcgcgtccaa taggttcagg tattttctag cctcctcaat atcccctcgc
     2341 cgcatatcaa tctccaccag ccgcttgatc tgccgtacgc ttctttgttt agggctgaac
     2401 aagattcctt cgatcgcccg gtgacgggcc atatccatat ctcccaattg ataatacacc
     2461 tcattactga aaaacacggg aagtatagaa gacctcaaat cgatcggcaa gaacaaggcg
     2521 tccgcccctc gttgataatg atccatcaaa ttctggggca actcgttctt cttggagaaa
     2581 gcgatattcc tataataact taccaagata tcgggagaat caaatccggc agacaaatcc
     2641 aagactcgct cccaatcacc cctatagatc gcttggtcta ctgccagaac cttttcccgc
     2701 ttccggttcg tacccgctat aacaaatgaa aagaatccaa atacgactaa aaaggttata
     2761 agcaagctat gccggttcag acgtatccta cgtatacctt taatctccaa agcgaatatc
     2821 tctagaatca acgctaaagc ggggaaatat acgctcaagc catccacatg ggaatattta
     2881 taggcctcct caatgctcaa tccataaaaa tgacgcatga acaacggata taaataactc
     2941 gataacaaaa gagaaagcca gaaccaccac cgtttcctat tcttggctcc ctcatagaat
     3001 atcaccatca aggagaagac aaacagccgg ctaccgacca tgctataaat tatgggaaga
     3061 agtataaaag ccacccaaac ggacgttctc ttattcttaa tccggatgta tcccaagaag
     3121 agccatagca cgaaaatcaa cgtaagcgta gacgctatac tatacgacaa ccggcaaatc
     3181 aatccccact ctaacgctac cggaaacaac gcatatatgg agaccatatt accattcccg
     3241 aacttgcgta aaacccgcat agagtagtac cataagagca acaacacgca cgtcacgatt
     3301 aacgggccta tcacagtcaa atggaagaac tgtatcaaga aattccccac ataacagctc
     3361 aaccaagccg gctcatccca gaacgaaata aaataatcgg tggtatacaa aaaaatcctc
     3421 atctgctctt tgaagaacaa atggtttggg taaatccatt gaaagaaagc aaagcatact
     3481 acgaagaata ttcccgctat tacccattga agcgatcgtt cattttttgt cattgacaaa
     3541 atctcttatt tataacctcc ctatttcctc aatatagaaa aaatcaattt cctcatcaat
     3601 cttttgaata caaaacaatg caaacaaaca aaaagttttg aataaataca aataaacaaa
     3661 tagaatcatg atcaagacgt cttgtttttc aagtagacga gccaagatat acaaaaaagt
     3721 ccctttatct accaataagc agataaaggg acctttttca aggacaacaa ttactattat
     3781 cctatcgttt tttcttagcc tcttgttgtt tacgcaacgt ctcctgctgt gctcgttgag
     3841 cctcttccag acgtttcatg aaaccggatt tcttcatcgg tttccgtttg tttgcctcca
     3901 acttagctaa caatttatcc tcattgatcg tatagcggaa gatcaatgtc tgcacgattg
     3961 tgatcaacgt agagatgaaa tagtaatacg tcaaaccgga agcatactgg ttgaagaaca
     4021 ccaagaacat caacggcatc atgtacatca tggccttcat gcccggcatc tgttgctgcc
     4081 cggtattcgt catctccata ttatacttgg tataaaaaat attcgtgatc gtcatcaaca
     4141 aacagaacaa actgatgtga tttccgaaat acggagtgat gatcggaata tatttattcc
     4201 aactaaagat agcgtcgtaa gtagacaagt cgtgcgccca aaggaaactc tggtgacgta
     4261 actcgatcgc cgacgggaag aacatgaata aagcgattaa gatcggcatc tgcaacaaca
     4321 tcggcaagca accactcatt gggctcgccc ccgcacggct atatagctcc atcgtcgctt
     4381 tctgccgttc catagcctta tcctgtccgg gatacttagc gttgatctcc tccacttgcg
     4441 gacgcaatac acgcatcttg gcggacgaca tataagactt atacgtcaac gggaaaagga
     4501 tgatcttcac gatgatagtc atcaaaagaa tcaagatacc ataattatgg ataaacttac
     4561 ccaagaagtc gaacaagggg atcacgaaat attggttcac ccagcggaag ataccccagc
     4621 ctagcggaac caacttctcc agatccagtt gctgctcggc agagactccc ttatcgaagg
     4681 acttcaacaa ggcgaactta ttcggtccga aataaaagga caggttcgtg gcctccttac
     4741 cttgcaagtc gaaaggtacg gaagcggtcg tcttgaattg tttcaacaca tccccctccg
     4801 gaatcgcttt cgagtctaag gtagtagcct caaagccctc ttgcgagatc aatacggtag
     4861 agaagaacat atccttataa ccgatccatt tcaagcggtt cgggatctgc ttgctgtcac
     4921 tcttcgactc gctcaggtgt tccacgtcgt ccgccatgaa cttgtagttc aaggtcacgt
     4981 agcgatcctc aaacttacgt cctttttcct gttggcggat atcctgctcc cacaacaaat
     5041 ccaaggcatt cgtgctcggt gccaagacac cgttcaatcc cgtacccaga atctggtatt
     5101 gcaccatata atcatccggt ttcaaggtat aggtaaaatc cagatgacta ccctcgccgg
     5161 tgttcaaacg catgatcacg gaattcgggt cattaccttt aaccggggta aaatacaaat
     5221 cgctcgtatt cacgacacgg ttcgttgccg tgaccaacgt gaaattaaaa ttagactctt
     5281 tctcgtcgaa caaaacgaga ggctcgtcat tatacgtatc atactccttc aagcgtgcgt
     5341 aacaaatacg tccgccctta ttgctgatac gcagctcgac cacgtcattt tgcagggtcg
     5401 tgtaatcttc cgtgcccacc atagcgtcgc cgaatacgcc gaagctctgc tgcaaacgtt
     5461 gcgcccgtac cgagtccggc aggttctcca acgaatcctc cactaaagca ctcttgttct
     5521 cttgtttctg caactccagt tgctgagcat actcaatctt cgcgattgaa tcttggtaac
     5581 ggcgctgtgc ctccaactgc tcaggcgttg gccggttgaa ccagctaaac gcgaataata
     5641 cgacaccgat cagcagaaaa cctattaatg tgtttttatc catttatcac caattatttt
     5701 ttattttcga tagcagcttt cacgaagctg aggaaaagag gattcggatt caccacggta
     5761 ctgttgtact ccggatgata ttgaacgccc acgaaccatt tcaaggcggg gatctctacc
     5821 acctctacca gatttgtctc cggattctca cccgtacaca tcataccggc ggcctcgtat
     5881 tgcttcttat actcgttgtt gaactcgaaa cgatggcgat gacgctcttg gatatgctcc
     5941 ttgccgtatg cctccaatac cttggagccc tctttcagcg tacagtcgta agcgcccaaa
     6001 cgcatggaac ctcccatatt ggtaacgttc ttctgctcct ccatcaagtc gatcacctta
     6061 tgtgccgtat tcggctccat ctccgtagag ttggcatccg ccaaacctaa cacgtcacgc
     6121 gcaaactcga tcaccatgca ctgcataccc aagcagatgc ccaagcaagg gacatcatgc
     6181 tcacgagcgt atttgatagc ggcaaacttg ccctcgatac ctctctgccc gaatccgggg
     6241 gcgatcaaga taccatccat atccttcaat tgctcggcgg cgttctcgtt atttaatttc
     6301 tccgaatgga acaaatgcaa atccagttta tgatgattgt aaatagcggc ttgcaacaaa
     6361 gactcgtcga tcgacttata agcgtcttgc aattccacgt atttaccaac caaaccgatc
     6421 ttcaccgtat ccgtagccgt gctcttcaag gcaaggaatt ccttccaagg cttcaactcc
     6481 ggagtcgggc cgacttccat acccacctta cgcaagacca cctcgtccat cttctggcgt
     6541 tgcaatacca aaggaacctc gtagatcgtc ggtacgtcga tcgactggat cacggaatcc
     6601 tcggccacgt tacagaacaa cgccacctta cgtaacaagt tcgcgttcag ctcatgctcc
     6661 gtacgtaaaa ccaacacgtc tggctggatg cctaattcct gcaattgctt cacggaatgt
     6721 tgcgtaggct tcgtcttata ctctttcgcc gcggcgatat aaggcacgta agtaagatgt
     6781 acgcaaaggc agttcttgcc cagctcccat ttcaactggc gaacgctctc tatgaaaggc
     6841 agagactcga tatcacccac cgtaccaccg atctcggtga tcacgaagtc aaatttatac
     6901 ttgctaccca ataatttcac gttacgcttg atctcatccg tgatatgagg caccacctgc
     6961 accgtcttac ccagataatc ccccttacgc tccttgttga tcacgctttg atagatacgt
     7021 ccggtagtga tattattcgc acgggtagtc tggacattca agaaacgctc gtaatggccc
     7081 aagtccaagt cagcctcatg tccatcgacg gtcacgtaac attccccatg ttcataaggg
     7141 ttcaacgtac ccgggtcgat gttgatgtaa ggatcaaatt tttggatagt aaccttgtaa
     7201 cctcttgctt gaaggagctt acctaaagaa gcggaaataa tacccttacc taaggaagag
     7261 accacgccgc ctgtaacgaa aatgtacttt gtatctgcca cgatagtaat attttagtta
     7321 tctttttaat tgcacacctg catttcgaaa ccgcaaagtt agcgattttc atcgagacat
     7381 gccaaattta atgtttttat ttctcgctga atatctccag aactgacccg ggcttcggca
     7441 ggactcttcc gattcccgac ccgaagcacg gcactaaaga cagtacttct catggaatta
     7501 cttcggtact acgtaggaag tactgaagta ctttgaccga agtattccag tacttccagc
     7561 ggagtactga ggcaagtccg tataagcctc gctagacaca cctgctttgc ctcagtgatc
     7621 gtaactttta cccagataaa tatcaaatcg tatgttgtat atcattcttt ttagctaatt
     7681 ttgcgaccac tacaactaat agatgtaaat aaggtattat gatgatgaag aggcatggtg
     7741 tgtatgcgct attattactt tcactaattg gaggctcggc atacagtcaa gagaaccagc
     7801 tagttaccgg aacgatagtt caacgtcccg cacagcaagt cgtatcggat gatacgattc
     7861 ccgcgatcaa tcttagcgaa gaggaattag acaacatcgt agacattcgt aagcaattcg
     7921 agaagcaaaa caagacttac tcggagccct tggccccaag cacgaattta ctgcgtttct
     7981 tgaagaaaga cgagctggaa atctcggacg aggcgatgta ttgggcccgt ctggtacgag
     8041 acgcctccac gattttcgat aatacgatga ccttccggga taccgtgatc gtaaaccctt
     8101 tgttcatgcc gatcgttttc cggggagatt atttacccga gaacttgata ttctacaact
     8161 tcgattcgtt gaaggagagg actccctatg ataacctata ccgggcagat tccattttca
     8221 aagatctgga acgaaacaaa caattcgagg agatggctta caaatatgta cagaacaatt
     8281 acccgactta tttccgctac tccgagaggg atctgcccaa tgaggtaatc aaacctaaat
     8341 tcatcaagaa gaatatttat gaggacttgc cgatcaaggt ggaggctgat gccaattttg
     8401 aggacgtaga cgctcccgcc cgctttatcc cggagcggag atactggata tcggccttcg
     8461 agagcgccat ccaattctcc cagaactacg tttcggagaa ctggtataaa ggtggaagta
     8521 gcaacttgaa cctgttcacc aagaacaatt taaaatacga ctataagaaa gataaggtac
     8581 aagtaacgaa cgaactggaa ttcaaagcca gcgtatatac ggcaccgaag gataccttaa
     8641 ggaactataa gatcggtgac gacgtattcc gtatacacag caacgtcggc taccaagcgt
     8701 tcaacaaatg gtactatacg ttcgacgctg agttcaagac ccagttcttc accaactacc
     8761 aagagaacga gcgcatcaaa caggccgcat tcctagcccc gttctctatc aacttcggtc
     8821 tcggtatgaa atacgagctg gaaaaacaat ttaccgacaa gcataagaag attaaattca
     8881 gcaccaactt ggcgccgatc tcctatacat atatgtatac gacacaagag atcgattata
     8941 gccgtcacgg tttcaagaaa aacgaggaaa ccggtgagtt caataacaag ctaagccaaa
     9001 taggttccac gatccgcgca gacctcgcct tcgatttcaa ccgtaacgta agctggcaat
     9061 cccgtcttta tttctttacc acttacggcg atcataccat cggggagttc gagaatacct
     9121 tggttctggc catcagccgc tttttctcca cacgtatcta ttttcacctt agatacgacg
     9181 atggagtgga aaaaacagag gataacaaga gttatttcca gcttaatgag ttgttaagtt
     9241 tcggttttaa ttacaaatgg taagctagga tttaagattt cgaataataa actttgttaa
     9301 tcgtgacata gtttctaaat tatacttact tttgccttga ttttgcaatg tcgagattac
     9361 aaatatgagc gaaagtataa atcatacagg atttgtagag aagatcgatg gcgacaccgt
     9421 cttcgtccgc attacccaac aatccgcatg ctcgggatgc cacgcacagt ctatgtgctc
     9481 ggcatccgag aaaaaggata agatcattga ggtacccgat cggtcgggac ggtttcacgt
     9541 aaacgaggta gtgataatat gcggacaaaa ttccatggga cttcaggccg tattgctagc
     9601 atttgtcatt cctttggtga tagtcgtggg ggccatcgta atcgggacga atctacaatg
     9661 ggacgagacc acgagcgggt taaccggttt atcgctttta ctgccttatt actgtatact
     9721 atacttaatg cgtgacaaac taaaaagacg atttatattt actttgaaaa aacttaattg
     9781 ataatatatc atgattttaa ttgccgttat ttcattagga gcaatcgggg cggtcggagc
     9841 ggttttcctc tacgctgctt ccaagaaatt tgaagtctac gaagatcctc gcatcgcaca
     9901 agtacaggaa gtccttcccg gggcgaactg tggaggttgc ggttatccgg gttgcgccgg
     9961 attcgcaggc gcttgcgtaa aagctgactc attagacgga ttgctctgcc ccgttggtgg
    10021 tggcccggtc atggccaagg tcgctacaat actgggtaaa gaggcgggta cagccgaacc
    10081 catggtagcc gttgtccgtt gcaacggaac ttgtcaggcc cgcccacgta caaactctta
    10141 tgatggaacg aaaagttgcg ccatcgcctc taccctttac ggaggcgaga cgaattgttc
    10201 tttcggttgc ctaggttatg gcgactgcgt gaacgcctgc gctttcgacg ccatccacat
    10261 caacccggct acgggaatcg ccgaggtaga cgaggaaaaa tgtacttcct gtggtgcttg
    10321 tgtgaaggct tgcccgaaga atatcatcga gctaagaaag aaaggaccta aatcacgccg
    10381 gatttacgtg tcttgcgtaa ataaggacaa gggagccgcc gctcgcaagg cttgtgccaa
    10441 cgcttgtatc ggctgtggca aatgtgccaa ggaatgtccg ttcgaggcaa tcaccgtaac
    10501 aaataacgta gcttatatcg attatacgaa gtgtcgttta tgccgcaaat gcgtggctgt
    10561 atgtccgaca ggagctattc atgagctgaa tttccctcct cgcaaggaag ccgctcccgc
    10621 tccgaaagcg gagaccgtga aaccggcgcc aaaggcagag gctaccgtga aaccggaagc
    10681 cgctccgaaa gctacaagtg aagaaaaaac aaatctaaat taaaatctaa tagtatgcta
    10741 aggacatttc gaatcggagg tatacatccc cccgagaata aactgtctgc cggtaagaaa
    10801 attacggctc tcgctacgcc taaacaggtg attatccccc tcagccagca tatcggtgcc
    10861 ccagcgcagg ccgtggtgaa gaaaggggat ctggtaaagg tgggtacatt gctagccaag
    10921 gcgggtggtt tcgtatcagc gaacatccac tcttccgtat ccggcaaagt gaacaagata
    10981 gataacgctc tcgacgctag cggatacaaa cgtcccgcta tctatataga tgtggaaggt
    11041 gatgaatggg aagagacgat cgaccgcagc gagaccttag tgaaggagtg cacgctgtct
    11101 tccaaggaaa tcgtggataa gatcgccgct tccggtatcg tcggtctggg tggagcgact
    11161 ttccctacgc aggtgaaatt gatgccgcct cccggaaaca aggcagagat cgtaatcatc
    11221 aacgccgtgg agtgtgagcc ttatcttact tccgaccatt cgttgatgct ggagaaaggc
    11281 gagcaaatcc tagtcggtgt cacgatccta atgaaagcgg tcaacgtgaa caaggccgtg
    11341 atcggtatcg agaataacaa gccggacgct atcgcccatc tgcaaaagtt ggcggtaaat
    11401 tataaaggta tagagatcat gccgcttaag gtacaatatc cgcaaggagg cgagaaacaa
    11461 ttgatcgacg ccgttattcg ccgtcaggta aaaagtggtg cgcttcctat ctcggcgggt
    11521 gccgtggtac agaacgtagg aactgcttat gccgtttacg aggcggtaca aaagaataaa
    11581 ccgttgttcg agcgtgtggt gacgatcacg ggtaaggcgg tagctaatcc ttccaatttc
    11641 ttggttcgta tgggaacacc gatcagttgc ttgatcgagg ccgcaggtgg cctgcccgag
    11701 aatacgggta agattatcgg tggcggaccg atgatgggta aagcgttgat cagcgccgag
    11761 gtgccggttt gcaaaggaag ctccggtgtt ttattactga caacggagga atctgtccgc
    11821 aagccgatcc gggattgcat ccgttgcgcc aaatgcgtag gtgtctgccc gatgggattg
    11881 aaccctaccc tattgatgaa cgccacggaa ttccagaatt gggaattggc ggagaagaac
    11941 tatatcaccg actgtatcga gtgcgggtcg tgtagttata cctgtccggc caaccgtccg
    12001 ttgctggatc agatccggtt gggtaaagga aaagttatgg gtattatccg gtctagaaag
    12061 tcataaaaca agagcaacat ggaaaataat ttatacgtat cgccctcgcc ccacatccat
    12121 ggaggcgaca gcataagcaa aaatatgtat ggtgtactga ttgcccttat cccggctttc
    12181 ttggtatccc tttatttctt cggtctggga gcgttgatcg ttacggtcgt atcggttctg
    12241 gcctgtatga tattcgagta tttgatccag cgattcctga tgaaaaagga accgaccctt
    12301 tgcgatggct ccgctatcct gacgggcgta ttgctggcct tcaacctacc ttccaacctt
    12361 ccggtctgga tcattatcat cggagcgttg gcggcgatcg gcatcggcaa gatgtctttc
    12421 ggtggattag gtaataatat tttcaatccg gcgttggtcg gacgtgtatt cttattgatc
    12481 tccttcccgg cgcagatgac gacttggccg gtagtagatg ccttgaacgt tttcccgatg
    12541 acttatacgg acgcccagac cggcgcgacg gtactgtcgt tgatgaacga gggcgtgacc
    12601 gagcttccgt cttacgggaa tatgcttgta ggggctatgg gaggtagtct cggtgaagtg
    12661 agcgccgtgg ccttgatcct cggtctttta ttcatgctat ggaaaaagat catcacttgg
    12721 cagatcccgg tatccatctt ggctaccgta ttcgtattca cgggcatcat gcacttggtg
    12781 aatccggtac aatacgccag cccgttcgtt catttattat ccggtggttt gttattaggc
    12841 tccatcttta tggcgaccga ctacgtaacc tcgccgatga gcaagaacgg aatgcttgtc
    12901 tacggcgtgg gaatcggaat ccttaccacg gtgatccgtt tgttcgggtc ttacccggaa
    12961 ggtatgtcgt tcgctatcct gatcatgaac gcatttactc cgctaatcaa cagctatatc
    13021 aaacctaaac atttcggagg aaagtaagca tggcaaaatt aaaatcaaca ttacccaata
    13081 tgctcctttc actaacaggc atttgcttgg tagcaggggc gatcctagcc ggagtgaacc
    13141 agtttaccgc cggccctata gcggtagcca aagcgaccgc cttggaggaa gcgattaaag
    13201 ccgttgctcc cgagttcgac aacaaaccga ctgaggacgt ctatatggcc gtctcctccg
    13261 atggtgattc cctcaagatt tatcctgcca agaaaggcgg acaagtcgtt ggcggagctg
    13321 tagagagtaa tacgaaaaaa ggctttagcg gtgagatacg ggttatcgta ggtttcgata
    13381 tggatggcaa gatcttgaac tattccgtat tgcaacacgc cgagactccg ggcttgggag
    13441 ccaagatgca agaatggttc cgtgcggaca agaacaagca aagtgtcttg ggacgtacga
    13501 ttccggacgg aggcttaaaa gtaacaaaag atggtggcga tgtggacgct atcacggcag
    13561 cgacaatctc cagccgtgcg ttcctcgatg ccgtgaaccg tgcgtatagc gcattcgctg
    13621 gcgtagacgg actaacgggt gccacttcaa ctgataacaa ataaaaaggg aggacagaac
    13681 aatgagtaat ctaaaaatat tgatgaatgg tatcatcacg gagaacccga catttgtatt
    13741 actgttaggt atgtgtccta ccttgggaac gacctcttcg gccatcaacg gcatgagtat
    13801 gggattggct acgatgttcg tattgatttg ctcgaatatc gtgatttccg ccttgaaaaa
    13861 cgtaatcccc gacttggtgc gtatcccggg atatatcgtt gtgatcgcga cgttcgtgac
    13921 cgtagtgcag atgtgcatgg aagcgttcgt cccggcttta tacgctagct tgggattatt
    13981 tatcccgttg atcgtggtaa actgtatcgt actaggacgt gccgaggctt tcgctgcgaa
    14041 gaacggcgta gtcccatccg ctttcgacgg aatcggtatc ggactgggct ttacgatggc
    14101 tcttacgctg ctgggcgctt gccgtgagtt cttgggaacc ggtaagttat tcaacgtaac
    14161 cttgatgccc gaggaatatg gttcgctgat cttcgtattg gctccgggag cgtttatcgc
    14221 cttgggttat ctggtagcaa tagtaaacaa actgcgtaaa gcataataaa cggatcatat
    14281 ggaatatata ttgatattta tcgccgccgt attcgttaat aacgttgtac tggcacagtt
    14341 cttgggaatt tgtccgttct tgggggtatc taagaaagtg gagactgccg caggcatggg
    14401 agccgccgtt acgttcgtgc ttacgatcgc tacgattgtt acattcctcg tgcaaaaata
    14461 catattggac gctttcggat tagggttcat gcagacgatc agtttcatct tgatcatcgc
    14521 cgccttggtt cagatggtgg aaatcatatt gaagaaggtc tctcccgccc tttaccaggc
    14581 gttgggcgta ttccttccgt tgatcaccac gaactgctgt atcttgggtg tggcgatcct
    14641 tgtaatccaa aaagagtata atttattaga atctgtggta tatgctatct cgaccgctat
    14701 tggatttgcg ctagctttga ttatcttcgc gggtattcgg gagcaactag ccatgacgca
    14761 tgttccggaa ggcatgaaag gcactcctat cgccttgata acggccggtt tgctagctat
    14821 ggcttttatg ggattctcgg gtatcgtata acaaacttat ctaaatgaac actagaatga
    14881 aaaagaagat tttagtagcg ggcggaaccg gttatatcgg ctcacacacc acagtagaat
    14941 tgcagaacgc cggatatgag gtagtcatta tcgacgattt gtcaaactcg aatatcgagg
    15001 tgctcgatgg tatcgagaaa atcacgggca tccgtccgga gtttatccaa ttggatctaa
    15061 aggataagga aggtactcgc aaggcattgg aagctcatcc gggcatcaaa ggcattatct
    15121 tgttcgccgc tagcaaggcg gtaggagaat ccgtacagca gcctttgaag tattatcgca
    15181 ataatattgt cactttggtg aacttgttgg agatgatgcc tgaattcaat atcgaaggta
    15241 tcgtattctc ttcctcttgt acggtatacg gacaaccgga tccggagaac ttgccggtaa
    15301 ccgagaatgc cccgatcaaa cccgctatgt ctccttatgg aaacacgaag cagat
//
