LOCUS       c00026_gnlPro..        14441 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDLNHNHA_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:10:55
            Original ID  :: gnl|Prokka|FDLNHNHA_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14441
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14441
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2412:4441]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2413..4441
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..14441
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14441
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             181..549
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="MRDLEKVCIQPKYNYCTGEERFTFIKLPKCLVEDEGFVELSMDAK
                     LLYALFLDRVSLSIKNGWIDNQGRVFIYYSIKNICVDLNCGTQKACKLLDELEKVGALE
                     RKRQGLGRPNKLYLKKMF"
     CDS             591..1403
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MSLRISAEDKEQIEEKERKNGLTTSEYIRRCALGRKLPCYGETSL
                     LKEYSMQLGKIGSNLNQIAKHLNSGGSYFSVYSDVKEAVKELLDLKFKILPALEDVACG
                     KKHRRMGYTEEKIKSIRYKMSLYDEFMEEYNCRKRNSNKIEKSKEISYRKDRGGKYLHK
                     LSPVRIINRGRNDNGKWCYIFPAIDIFPADFVIAFFSFTVVIQMIPLPNHFLKIRNTSC
                     RIFHSLQSNGLYITFQKSSVRMLIFTEVRQFLLFCMVYLSVIPALYIK"
     CDS             1848..2039
                     /locus_tag="ctg26_3"
                     /transl_table=11
                     /translation="MEWYQMDAGKCLEFSKKMAVLRKLVRLGLISENEYIRAKNRIMSS
                     YHILESEYFKSGTGKRVA"
     CDS             2032..2181
                     /locus_tag="ctg26_4"
                     /transl_table=11
                     /translation="LLSKEGLIMADQTLPLNVSDEMKSDDERQNCVGMENDEELCSSSA
                     TDKL"
     CDS             2413..3879
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_5"
                     /sec_met_domain="gallic_acid (E-value: 4.1e-228, bitscore:
                     748.5, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVNDLRSALEVLKQMDVQLVETDIEVDPEAELAGVYRHVGAGGT
                     VMRPTKIDGPAMIFNNIKNHKDARVLIGLLASRERVAKLMDCKKEELGKLLCRAALNPI
                     EPVVSEEKAPCQEVIHKVTDPDFDLFKLFPAPTNTPVDAGPYITMGMCYATHPDTGCSD
                     VTIHRMCIQSKDELSIFLQPGSRHIGVMAERATELGQPLPISISIGVDPAIEVGSCFEP
                     PTTPLGYNELSIAGAIRKTPVVLAPCVSIKENAIANAEYVIEGEIQPGIRVVEDQNTHT
                     GYAMPEFPGYNGLASHECWLIKVKAVTHRKNPIMQTVIGPSEEHVNLAGIPTEASIYNM
                     LEKALPGKVTNVYAHPSGGGKYMAVLQCRKTVHTDEGKQRQAALLAFSAFPELKHVILV
                     DEDVDIFDTRDVLWAMNTRFQGDRDIITIPGVRCHPLDPSSDPAYSQSISDKGISCKTI
                     FDCTVPFELKDKFARAKFMDIDEEKWKDFI"
     CDS             3881..4441
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_6"
                     /sec_met_domain="Flavoprotein (E-value: 1.4e-26, bitscore:
                     84.6, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKILVGISGASGAPIAIRLLKRLREMADVETHLIMTKGAELTIA
                     QETDCTVEQVKALADVVYDVSSLGECPASGSFKMDAMIIVPCSMKTAAGIASGYSDNLL
                     LRAADVTLKEARQLVLVARESPLSPVHLRNLHELSSMGVRVVPPMISFYQKYTTIEAWT
                     DNFAERLLEILGLHNTMQSWSGM"
     CDS             4470..4814
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="LINLIEKQIVLLDRSVQVSVCRTECGIQVLIAGGDRPHIGAVSIV
                     DEKSNLISHVFEGHKDYVISDRWAVKLYEHFLVPMVVSAGIHYDEITPDGIKTVIEEME
                     KLLEEVMAYE"
     CDS             complement(4861..5787)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     63.9; E-value: 3.2e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="LysR_substrate (E-value: 1.9e-30,
                     bitscore: 97.3, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.3e-20, bitscore: 63.9,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTENLKEFIVLAETKNFWEASERLYMNQSTLSKHIKSLENDLGV
                     ALFTRTTRRVELTNYGEIFLPYAKSVTRSEFEGISAIQRMLNIENGLLTIGTIPSMPQY
                     HITQFLSQFQKLYPETTVRITEDDPVNLMPYLENEKCELIFNREDKVTFEKNFLNDHHI
                     LRIPYMSDHLVALIPLSHPLASSSSITLQQLKNDRFCFIKEGSLMYQMSMDACQNAGFI
                     PDIVFTSHRIDSILDMVTNQNCVALLMNVHLQLPENGPKQTGAPWCAVPITPVISSQLS
                     LCYRCDKPLSKTAQLFVNLCNDKLFKS"
     CDS             5906..7216
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_2"
                     /gene_functions="transport (smcogs) SMCOG1005:MFS sugar
                     transport protein (Score: 256.8; E-value: 9.4e-79)"
                     /gene_kind="transport"
                     /locus_tag="ctg26_9"
                     /sec_met_domain="MFS_2 (E-value: 6.8e-79, bitscore: 256.8,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENRKKVPLKNKLAYGIGTGGGNVFSQIAAAFLLNYYTDTALIGA
                     GAIATMFLVCRVFDGITDLLMGGIVDKTSTKLGKARPWLIASAPLSFLGIVLLMNVPMG
                     LGENGKLVYAYITYIFMSCIVYTIYGISNTALLPLMTHDKDDSTMLATFSALGNNIIGL
                     IAGSLITPLVLNLGWKTSSIILGFAACVLILISGLLNKEMGNDEDTKKMAGIPMSQQLP
                     ATLKNKYFWLLLLLGAFSLIMNANAIGAQIYYCNMVLGKPMFMSALMTAGQLPGIFILF
                     LMPAVSKKWNKKTFLLMGAVLIIVGFVITGIAGGNTTLIVIGTVIRSLGVGPILSAVFA
                     LVPDVVQYGNWKYGIRSEGLISSAQSIGSKIGIGIGSALTGWILASVGYNPAAEPTAAV
                     INAVKFDYTWMGAILGVVILVIVLLLDVEKYADQYNS"
     CDS             7237..8715
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MYDLKFDPEKYEIKTCELQNRSVTYRAFENIVYCAKPVSSVQKLN
                     IYVPEAYYQGKTINGYDLKTAPVFAPNTVGGYMEGPAMEVGIDPFNHKPNTAFEALLHG
                     YVVLCAGIRGRNTGMDSQEFFVGGSGKENTGKEEKLTGCAPAIIVDMKAAIRYMRYNAD
                     VIPGDVEKIITNGTSAGGALSALAGASGNAKEYEPYLKAIGAADERDDIFAASCYCPIH
                     NLENADAAYEWLFQKESVFHMMKFEMSPEGPKMIPVAGALDEEQRKLSKELKAEFPDYV
                     NSLHLKDDNGNELTLDKEGEGSFKDYVMSFVLASATKERADLDSQNKLKGLAVPGSEIA
                     EQNYITYTGNEATGIDMEAYVAKITRMKPTPAFDSLSLNSPENEEFGDENVFARHFTRF
                     SAEHSKVHGEMADADRIRLLNPTRFIGTCDTTKNWRIRHGAFDRDTSIAIPVILAAMLK
                     NKHYNVDFALPWGLPHSGDYDLEELFAWIDGLGK"
     CDS             8785..9255
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_11"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.1e-16,
                     bitscore: 51.3, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFIYKTATHQDIDILVTTRIEVLRAANKLADQVDMSEVAAQSRD
                     YYEKALKDGSHTAILVYDKDQIIGAGGISYFRVMPTYHNPTGRKAYIMNMYTNPAYRRK
                     GIAYQTLNLLVADAKNKGIDAISLEATEMGRPLYEKFGFTGMNDEMELKKSV"
     CDS             9380..9658
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="MTIKQRIFRTNSLMVLFSLVILLLIGGSMISIFKDRFLGWYSDNS
                     KISEKYVDAYQKIENMDFSAGDWEQYAKAVQPYDFHLIVRDENGKEL"
     CDS             10030..10758
                     /locus_tag="ctg26_13"
                     /transl_table=11
                     /translation="MRIIIVRHGDPNYELDTLTKTGWREAELAAEYLAKLQIKAFYVSP
                     LGRAQDTAGCTLKKMNRTAETLDWLREFEAHIDRPDVKNEKSICWDWLPQDMEKDLDLY
                     DRERWNKTDIMRKGNVEEAYRWVCDGLDALLKRHGYERDDMYYRVNEPNHDTIVLFCHF
                     GVECVMLSHLLNVSPMVLWHGLCAAPSSITSIYTEERRKGIAGFRVNEFGSTAHLYVAG
                     EKPSFAARFCECYGDGDRQD"
     CDS             10986..11924
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.9; E-value: 2.3e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_14"
                     /sec_met_domain="Peripla_BP_3 (E-value: 1.6e-33, bitscore:
                     107.9, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPNEAARNLKKGITDTSQKVWYLDVLMTRMGNLETDPFFSELLRV
                     IESEIHRQGCILMHIFHQPLFSNDRKCRTENIDKVIAQMEPDGDIRSDGLIIIGKCNDN
                     VLKKLSAKYKSIVSVNRNSTNYLVDEVICDGKRIAAMAVEYLIGLGHRKIGYVGDCHNE
                     SRYKGYQDTLFQYGIDIDISFVIEAEHTEAEGYAVMERLIQRGDAPTAIYCANDMIAIG
                     MLKCLNKYKNRYYVPSIISSDDIEEAQYTRPMLTTVRIPKEEMGKFALYLLIDRLGGGH
                     KGIVRTELEGKLMIRESCTLVENANRMEYYI"
     CDS             12613..13674
                     /locus_tag="ctg26_15"
                     /transl_table=11
                     /translation="MYIELKDINKTFGNYKASDHVEFGIEKGKLVALLGPSGSGKTTIL
                     RMIAGLEHQDSGDIYIDGTCVNELLVRERGIGFVFQNYALFPYMTVFDNVAYGLKVRKE
                     DKKVIEKRVKELLELVDLKGLEKRYPTQLSGGQRQRVAFARALAPNPQVLLLDEPFAAI
                     DAKVRKELRNWLKDMIGKIGITSIFVTHDQDEAVEVADEIIVTNQGRVEQMGTPTEIYK
                     NPKTPFVAQFIGESAVITDYDRLKGFHLYQGCDRAIIRPEFVKAVRFGTEKRFQSLYAE
                     GIVEQVAFRGNCLELQINVNGILLKTIQSFAEEPFQKGEKVEVIVYRLYAVDEKEAHLI
                     QNEGLQENEMFYI"
ORIGIN
        1 atctttatga ggaagattca aagaagaaaa agtgatttta tggtaaagcg tcagcgtggc
       61 tctgcggttt atccgcagtt caaggggatt ggggcattcc ccaacaagca aaaatgcgcc
      121 gggtatatac cggagcactg cttgccaatt tgtaaaaaga gaaaagaaag gattaagttt
      181 atgagagatt tagaaaaggt atgtattcaa ccgaagtata actattgcac cggtgaggag
      241 cgttttactt tcatcaagct gccaaaatgt ctggtagagg atgaaggctt tgttgaactg
      301 tcaatggatg caaagctttt atacgcactc tttttagatc gagtttcatt gtcaataaaa
      361 aatggatgga ttgacaacca agggagggtg tttatctatt attcaataaa aaatatttgc
      421 gtggatttga attgtggaac tcaaaaggca tgcaagttat tggatgaatt ggaaaaggtg
      481 ggagcacttg aacggaagag acagggattg ggaagaccta acaagctgta ccttaagaaa
      541 atgttttgag aaatagccat acagataaaa agaaagataa caaggttctt atgtccttgc
      601 gtatatccgc agaggataag gaacagatag aggaaaaaga aaggaaaaac ggacttacta
      661 cgtcggaata tatcagaaga tgtgctctgg gaagaaagct tccatgctac ggagagacaa
      721 gtctgttaaa ggagtattcc atgcagcttg gaaagattgg ttccaatcta aatcagatag
      781 cgaaacatct gaatagtggc ggttcctatt ttagtgttta cagcgatgtg aaagaggcag
      841 tgaaggaatt gctggattta aagtttaaga tacttccggc attggaggat gttgcatgtg
      901 gaaaaaagca cagacgtatg ggatatacag aagaaaagat aaagagtatt cggtataaga
      961 tgtccttgta tgatgaattt atggaagaat acaattgcag gaaacgaaac agtaacaaaa
     1021 tagaaaaaag taaagagatt agttacagaa aagatagggg aggaaaatac cttcataagc
     1081 tgtcaccagt aagaataatc aataggggca ggaatgacaa tggcaagtgg tgctacatct
     1141 ttcctgctat cgatattttc cctgccgatt tcgtgatagc gttcttttca ttcacggttg
     1201 tcatccagat gatcccattg cctaatcatt tcctcaaaat cagaaatact tcttgccgca
     1261 tcttccattc gcttcagagc aatggcttgt atatcacgtt tcaaaagagt tctgtcagga
     1321 tgctcatatt cacagaagtc cggcaattcc tgttgttttg tatggtttat ttatctgtaa
     1381 tacctgcctt atacataaaa taatcagagt tcatcagaag cttacttttt gcaagaaatc
     1441 tgattttttc aaaaacgctt ctaaatctcc tataagtgag agagtaatct ttttaaatat
     1501 aaaaatatta cttcaaacat taaagcgtga agtgattcat acaatcagta tagcataaaa
     1561 caaacgcatg ttctacaact atttaataaa aatcgaatat ttgtttggta atggttactg
     1621 ttcacaggta ggcattttct gaactgaaaa tgccgtatga tacagtggtg gtagcagatt
     1681 ttgccgattt ggaatgcgaa gcatcggcaa aatccgttac tggaacgagg tacgagtgaa
     1741 cagtaactgg taatgctggc ggagtggtgt gaatagcaat tgtaagtgta tgtgagactg
     1801 gttgtttgta attcgtgaaa agctgtattt tgagaggagg ttttgctatg gagtggtatc
     1861 agatggatgc aggaaagtgt ctggaattca gcaagaaaat ggcggtgctt agaaaactgg
     1921 ttcgccttgg cctgatttcg gaaaatgaat atattcgggc aaagaatagg attatgagtt
     1981 catatcacat tctggagtca gaatatttca agtccggtac aggaaaaaga gttgcttagc
     2041 aaggaaggct tgattatggc tgatcagact ttaccattga atgttagtga tgagatgaaa
     2101 tcagacgatg aaagacagaa ttgtgtagga atggagaatg acgaagaatt gtgttcttct
     2161 tcggcaaccg acaaattgtg agaccgtgtg cctgctgggt agatgaaaag gaagcaaggt
     2221 aaaaagctgt tgttggaaca gaaaacaaac atcacaagtt ttttataaaa aagattaatg
     2281 aaatccaaca tttcctcaca ttaagtcaca aaccgaatta atatccccct tattttgaat
     2341 ttttctatag caggatgtct actataataa agttatcaat cgattattta aaataaggag
     2401 atgatatcaa ttatggtagt gaatgattta agatcagcgc ttgaagtgtt aaagcagatg
     2461 gatgtccaac tggtggagac tgatattgaa gtggatccgg aagcagagct tgcaggggtg
     2521 tacaggcatg tgggagcagg cggtacggtc atgcgtccga cgaaaattga cggaccggct
     2581 atgatattta acaatataaa aaatcataag gatgcgagag tgctgatcgg tctgcttgcc
     2641 agcagggaac gtgttgcgaa acttatggac tgcaagaaag aagaacttgg aaaacttttg
     2701 tgcagggcgg ctttaaaccc gatcgaacct gttgtctcag aggaaaaggc accatgtcag
     2761 gaagtgatac ataaagtaac ggatcctgat tttgatttat tcaaattatt cccggcaccg
     2821 acgaacactc cggtggacgc aggtccatat atcacaatgg ggatgtgcta cgcaacacac
     2881 ccggatactg gatgctcgga tgtgacgatc cacaggatgt gcattcagtc aaaggatgaa
     2941 ttatccatat ttctacagcc gggaagcaga catatcggtg tgatggcaga aagggcgaca
     3001 gaactcggtc agccgcttcc gatttctatt tcgatcggtg ttgatccggc gatagaagtt
     3061 ggttcctgct ttgaaccgcc aaccacaccg cttgggtata acgaactttc gattgcgggt
     3121 gccatcagaa agactccggt ggtactggca ccatgtgttt ccataaaaga aaatgcaatc
     3181 gcaaatgctg aatatgtgat tgaaggagaa atccagccgg gaatcagagt ggttgaggat
     3241 cagaatacac atacgggata tgcgatgccg gaattcccag gatataatgg actggcaagt
     3301 catgagtgct ggcttataaa ggtaaaggcg gttacgcata gaaagaatcc aatcatgcag
     3361 acggtgatcg gaccaagcga agagcatgtg aatctggcgg gaattccaac agaggccagt
     3421 atttataata tgcttgagaa ggcattgccg gggaaggtaa cgaatgttta tgcgcatccg
     3481 tcgggtggag gaaaatatat ggcagttctc cagtgcagaa agaccgtgca tacggatgaa
     3541 ggaaagcaga gacaggcagc gctgctggcg ttcagtgcgt ttccggagtt gaaacatgtg
     3601 atcctcgtag atgaggacgt ggatattttt gatacgcgcg atgttttgtg ggcgatgaat
     3661 acgcgatttc agggagatcg ggatatcatt acaattccag gggtaaggtg tcatccgctt
     3721 gacccgagtt ccgatccggc ttacagccag agcatttccg ataagggaat cagctgcaag
     3781 acgatttttg actgtacagt accatttgaa ctgaaggata aatttgcacg ggcgaaattt
     3841 atggatattg atgaggaaaa gtggaaggat tttatttgat atgaaaaaaa ttctggtagg
     3901 gataagtggg gcatccggag ctccgatcgc gatcagactg ttgaaacggc tgagagagat
     3961 ggctgatgtc gagacacatc tgatcatgac aaaaggggca gaacttacca ttgcccagga
     4021 aacggattgt acagtagagc aggtaaaggc acttgcagat gtggtgtatg atgtgtcttc
     4081 acttggcgaa tgtcctgcgt cagggagttt taaaatggac gcaatgatca ttgttccatg
     4141 ttcaatgaaa acagctgcgg gaattgcttc cggttacagt gataatctgc tcctgcgtgc
     4201 agcagatgtg acgttgaaag aagcaagaca gttagtactt gtggcaagag aatcgcccct
     4261 tagtccggtt catctcagga atcttcatga gctgagttcc atgggagtcc gcgttgtacc
     4321 gccaatgatc agtttttatc aaaaatatac gacgattgaa gcgtggacgg ataattttgc
     4381 ggaacggttg ttggaaatat tgggattaca taatacaatg caatcctgga gcggaatgta
     4441 gagggacgca tcagagcagg tggtgtaaat tgataaattt gattgaaaaa cagattgtac
     4501 tgttagacag gagtgtacag gtatccgtct gcaggacgga atgtgggata caggtgctga
     4561 tcgcaggcgg ggacaggcca catataggcg ctgtgagcat tgtagatgaa aaatctaatt
     4621 tgatctcgca tgtttttgaa ggacataagg attatgtgat cagtgacagg tgggcagtta
     4681 agctgtatga acatttttta gttccgatgg tggtatctgc tgggattcat tacgatgaaa
     4741 ttacgccgga tgggataaag acagtgattg aagaaatgga aaaactgtta gaagaggtaa
     4801 tggcgtacga ataaaaaagg cggaaaaggt gtgattcatc ttttctgcct tttttgtggg
     4861 tcaggatttg aacaatttat cgttgcataa atttacaaat aactgtgctg tttttgaaag
     4921 aggcttgtcg cagcggtagc ataatgaaag ctgtgatgaa ataacaggcg tgataggaac
     4981 agcacaccat ggagcaccgg tttgttttgg accattttcc ggaagctgaa gatgaacgtt
     5041 catcagcaga gcgacacagt tttggttggt taccatgtct aaaatggaat caattctgtg
     5101 gctggtaaaa acgatatctg gaataaaacc tgcattctgg catgcatcca ttgacatctg
     5161 gtacatcagg gaaccttctt ttataaaaca gaaacgatca tttttaagtt gctgcagggt
     5221 aatagacgaa gaagacgcca gagggtggct gagtggaatc agtgcaacca gatgatcact
     5281 catgtaaggg atcctcaaaa tgtgatggtc attgagaaag tttttttcaa aagtaacttt
     5341 atcttcacgg ttaaagatca gctcacattt ttcattttcc agatatggca ttaaatttac
     5401 aggatcatct tctgtaatcc gtacagtagt ttctgggtat aatttctgaa attgtgaaag
     5461 aaactgagtg atgtgatact gtggcataga aggaatcgta ccgatggtga gaagaccatt
     5521 ttcgatatta agcattctct ggatggcaga aattccttca aattcggaac gggtaacgga
     5581 ttttgcgtaa ggcagaaaaa tttctccata gtttgtgagt tctacccgtc ttgtggtgcg
     5641 tgtaaataaa gccacaccga ggtcattttc cagacttttg atatgttttg ataacgtgga
     5701 ctggttcata tagagccgtt cagaggcttc ccaaaagttt tttgtttcag caaggacaat
     5761 aaactccttt aaattctcag tattcatgca tccgttctcc tttaagtctg tttctgactt
     5821 aattctatcg gaacccgaat tgtttgtcaa cgcggggcaa aatataatag aaatatcaaa
     5881 aaaatatatc ttttgggagg taaatatgga gaacagaaaa aaagtgccgc ttaaaaataa
     5941 gctggcgtac ggtattggaa caggcggggg aaatgtgttc agtcagatcg cggcggcatt
     6001 tcttctcaat tactacacgg acacagcact gataggtgca ggtgccattg ctacgatgtt
     6061 tctggtgtgc agggtttttg atggtattac ggatctgctc atgggtggca ttgtggataa
     6121 gacatctaca aaactaggca aagcaagacc atggctcatt gcttcggcgc cgctttcatt
     6181 cttgggaatt gttcttttga tgaatgttcc aatgggactt ggagagaatg gaaaacttgt
     6241 atacgcttac attacatata ttttcatgag ctgtattgta tacactattt atggaatctc
     6301 caatacagcc cttctgccac tcatgacaca tgataaggac gattctacaa tgcttgcaac
     6361 attttctgct ctgggaaata atatcatagg tctgatcgca ggctccctga ttacgccgct
     6421 tgtattaaat cttgggtgga agacatcaag catcatttta ggttttgctg cgtgtgtcct
     6481 tattctgatt tcaggattgc tcaataaaga aatgggcaat gatgaggata caaagaaaat
     6541 ggcaggcatt ccgatgagcc agcagctccc ggcaacttta aagaataaat atttctggtt
     6601 attattgctg ctcggcgcat tttcacttat tatgaatgca aatgcgattg gagcacagat
     6661 ttactactgt aatatggttt taggaaaacc gatgtttatg tcagccctta tgacagcagg
     6721 acagcttcca ggtattttta ttctgtttct tatgccggcc gtttcaaaga aatggaataa
     6781 aaagacgttc ctgcttatgg gagcagtact gatcattgtg ggatttgtca ttacaggtat
     6841 tgccggtgga aatacaacgc ttatcgtgat aggaaccgtg atccgctcac ttggtgttgg
     6901 accgatcctc tcagcggtat ttgcacttgt cccggatgta gtgcaatatg gaaactggaa
     6961 atatggtatc cgttccgagg gacttatttc atccgcacag tccatcggtt ctaaaattgg
     7021 tatcggtatt ggcagtgcac tgacgggctg gatccttgca tcggtaggat ataacccggc
     7081 ggcggagccg actgcagcag tgatcaatgc agtaaaattt gactatacat ggatgggggc
     7141 tatcctcgga gttgtaattc ttgttattgt attattactt gatgtagaaa aatatgctga
     7201 tcagtataat tcgtaaggaa agaggtatgg gataatatgt acgatttgaa atttgatccg
     7261 gagaaatatg agataaaaac ctgtgaactt caaaacagga gtgttactta cagggcattt
     7321 gaaaatatcg tttattgtgc aaagccggta agcagtgtac agaaattaaa tatttatgtg
     7381 ccggaagcgt attatcaggg aaaaacgatc aatggatacg atttaaagac agcaccggtt
     7441 tttgctccga atacagtagg aggatatatg gaaggtcctg caatggaggt tgggatagat
     7501 ccgtttaatc ataaacctaa tacagcattt gaagcgctgc tgcacggata tgtagtattg
     7561 tgtgcgggga tcaggggacg taataccggt atggattccc aggaattttt tgtgggcggt
     7621 tccggaaaag agaataccgg gaaagaggaa aagttgacag gatgtgcacc tgctattatt
     7681 gttgatatga aagctgcaat cagatatatg agatataatg cggacgtgat cccgggagat
     7741 gtggaaaaga tcattacaaa tggaacatcg gcaggaggtg cactttctgc actggctggg
     7801 gcttccggta atgcgaagga gtatgagcct tatctaaaag cgatcggtgc ggcagatgag
     7861 agagatgata tctttgctgc aagctgttat tgtccgatcc ataatcttga aaatgcagat
     7921 gctgcgtatg aatggctctt tcagaaagaa tccgtatttc atatgatgaa attcgagatg
     7981 agtccggaag gtccgaaaat gatccctgtt gcaggggcac tggatgagga gcagagaaaa
     8041 ttatccaaag agctgaaagc agagtttcct gattatgtaa acagcctgca tcttaaggat
     8101 gataatggga atgaacttac tcttgataaa gaaggtgaag gttcctttaa agattatgta
     8161 atgagttttg ttcttgcatc agccacaaaa gagagggcag atcttgattc acaaaacaag
     8221 ttaaaaggac ttgctgttcc aggaagtgag attgcagaac aaaattatat cacctatacc
     8281 ggaaatgagg caaccggtat agacatggag gcatatgtgg caaagattac ccggatgaag
     8341 ccgacaccgg catttgattc attgtcctta aacagtccgg agaatgaaga atttggcgat
     8401 gaaaatgtat ttgcaagaca ttttaccaga ttttcggcag aacattccaa ggttcatgga
     8461 gagatggcag acgcagacag aatccgtctg ctcaatccta cccggtttat cggaacatgt
     8521 gatactacaa agaactggcg gatcagacat ggtgcatttg acagagatac ttcgattgca
     8581 atccctgtta ttttagctgc catgctcaaa aataaacact acaatgttga ttttgccctg
     8641 ccgtggggac tgccgcacag cggtgattat gatctggaag aattgtttgc atggatcgac
     8701 ggtctgggaa aataaaggtc tgcaattctg ttgccaattg attagaacat cggtataatc
     8761 ataggcagag aggacggaat atttatgaat ttcatctaca aaacagccac ccaccaggat
     8821 atagacattt tagttaccac caggatcgaa gttttaagag ccgcaaacaa attagccgat
     8881 caggtggaca tgtccgaagt tgcggcacag tcgagagact attatgaaaa agccttaaaa
     8941 gacggcagcc ataccgcaat actggtctat gacaaagacc agatcatcgg cgcgggcggt
     9001 atcagttatt tcagggtcat gccgacctat cacaacccga ccggaaggaa agcttatatt
     9061 atgaatatgt atacaaatcc ggcataccgg cgaaaaggga ttgcatacca gacgctgaat
     9121 ttactggtgg cggatgcaaa gaacaaagga attgatgcga tttctttgga ggcgaccgag
     9181 atgggacgcc cgctgtatga aaaattcggg tttaccggga tgaatgatga aatggaactg
     9241 aaaaaatcag tttaagattt gtttataaaa gacacctttt gtatttacat ttagacgtta
     9301 tcatgatgta atgagtgaaa gtaatgagac atgcttacag gaatgataaa taacaaatgt
     9361 agaacaaaag gtgtttttta tgacgataaa acagaggatt ttccggacaa attcacttat
     9421 ggttctgttt tcccttgtaa tcctgctttt gatcggtgga agtatgataa gtatttttaa
     9481 agaccggttt ttagggtggt atagtgataa ttctaaaata tcagaaaagt atgtggatgc
     9541 gtatcagaag atagaaaata tggatttttc tgcaggggac tgggagcagt acgctaaggc
     9601 ggtgcagcca tatgactttc atctgatcgt ccgggatgaa aatggaaaag agctttaaga
     9661 ctggcggtaa gcagtttttc cgtgctgttt cctgctggat gtagtatttt tatcagcttt
     9721 tcccaaacgt tcctcaggca tatttttgcg cagaaaatca taagcttcat tgatctcctg
     9781 tgcagtaaaa tcataggctc tggtagaaaa tgcttccgtg tcaggatgta cccggtgcat
     9841 cagctgtcgg tatttctttt tgatatccgt aagagctgtt ccagaggtga ttcccaggat
     9901 tttgtacgcc attgcttttg tcataaatcg agtatatcat aaaagagaaa aaggttgtgg
     9961 gaaaaattta gacatattaa aaaccacctt ttgcccctaa atcttcatgg aaaatcagga
    10021 ggaacacaca tgagaatcat aatcgtaaga catggcgatc caaattacga actggacaca
    10081 ttgacaaaaa ccggatggag agaggcagaa cttgcagcgg aatacctggc aaaactgcag
    10141 ataaaggcat tttatgtatc accattggga cgggcacagg ataccgctgg atgcacctta
    10201 aaaaaaatga accggacggc agagacacta gactggctcc gtgagtttga agcacacatt
    10261 gacaggccgg atgtgaaaaa tgaaaagtcg atctgctggg actggcttcc acaggacatg
    10321 gaaaaggatc tggatcttta tgacagggag cgctggaata agacagacat catgcgaaaa
    10381 ggaaatgtgg aagaagctta tcggtgggtc tgcgatggtc tggatgcatt actgaaaagg
    10441 catggttatg agcgggatga tatgtattac cgcgtgaatg agccaaatca tgacacgatc
    10501 gttctgttct gtcatttcgg ggtagagtgt gtgatgttaa gccatctgtt aaatgtatct
    10561 ccaatggttt tgtggcatgg gctgtgtgcg gcgccgagct cgatcaccag tatttatacg
    10621 gaagagcgca gaaaagggat cgcaggtttt cgtgtgaatg aatttggcag cacggcgcat
    10681 ctgtatgtag caggggaaaa accatccttt gcagcgcggt tttgtgagtg ttatggggac
    10741 ggggacagac aggattaaaa ttttgaatag ctattgacaa aaacttcccc ttgctttatc
    10801 atccacttaa catatggaaa tagtaggaaa taaaacgggg tgaggttttg tctattaaga
    10861 aaattgcaaa ggaagcggga gtttccacag cgacagtctc gcgggtgttg aacaatcccg
    10921 ggtataaatg ttcttcggag gaattgcggg agcggatctg gaagattgcc agagaactca
    10981 attacatgcc aaatgaggcg gcgagaaatt taaaaaaggg aattacggat accagtcaga
    11041 aagtgtggta tcttgatgtg ctgatgacaa gaatgggcaa tcttgagaca gatccgtttt
    11101 tcagtgagct gctgcgtgtc attgagagtg agatccacag gcagggatgc atactgatgc
    11161 atatttttca tcagccgttg ttttcgaatg acagaaaatg ccggacggaa aatattgata
    11221 aggtcattgc gcagatggag ccggatgggg acatccgcag tgatggactg atcatcattg
    11281 gaaaatgtaa tgataatgta ctcaaaaagt tatcggcaaa gtataaaagt attgtttctg
    11341 tcaaccgaaa ttcaaccaat tatctggtgg atgaggtcat ctgtgatgga aagcggatcg
    11401 cagcgatggc ggtggaatat ctgatcggtt tagggcatcg gaagatcggc tatgtgggag
    11461 actgccacaa tgagtcgcgc tataagggat atcaggatac gttgtttcag tatggaattg
    11521 atatagatat cagttttgtg atcgaggcag agcacaccga ggcagaaggt tatgctgtga
    11581 tggaacgcct gatccagaga ggagatgcgc cgactgccat ttactgtgca aatgatatga
    11641 tcgctatcgg catgttaaaa tgcctgaaca aatataagaa ccgttattac gttccatcca
    11701 ttatttccag tgacgatatt gaggaggcac agtataccag accgatgctt actacggtgc
    11761 gtattccaaa ggaagagatg ggaaaatttg ctctttatct tctgatcgac cgccttggcg
    11821 gcggacataa ggggatcgtc cggacggagt tagaaggaaa actgatgatc cgggagagct
    11881 gtacgttagt ggagaatgca aaccggatgg aatattatat ctgagagaaa acaggtcatg
    11941 gacctttttt aattcatagg attcgggtgt caaaaggtgg ttgcaatttg ccagccacta
    12001 agttgtgagc caccttttga catccgaatc tttgcaggca cttgtagata ccggaaatgc
    12061 ttttgaagtg gtactttctt ttcacaatga ggaaaaagag atgatatttt tataaaacac
    12121 agagaactct ttctgtatgg tttaaaaccg tcaggaggag ttctttttta attcatagga
    12181 aattacgtcc tatgaattaa aaagccctcc gggcgggatg cgcatctcgc ggagtagaag
    12241 ttagctgtaa acagcaccgc tcgagcgcga aagagtcgca agcgactctt tgttccttta
    12301 aggtatgtaa acgtttgcag gaaaataaaa ataattggaa aattatgaat aaaaacatac
    12361 ataaaaaacg aaacaaacag tggaaaaaag acagtgtata cgttttcgcg aaaactgaaa
    12421 aacaataaac ccaaacaggg aaggacagaa gaaaaacagc tgtttttact ggaaaaataa
    12481 ggaaaacacc accatccatg caaacgatta cacaatcagt cgtggaatct tatacaaaac
    12541 tggtatataa atacatcaag caagacgtcg aagcagaaaa caatcacaca gcaaaaggaa
    12601 aggagatcgg atatgtatat cgaattaaaa gacataaaca aaacatttgg aaattataaa
    12661 gcatccgatc atgtagagtt tggcattgaa aaaggaaagc tggttgccct gttaggaccg
    12721 agtggcagcg gaaaaacgac gattctccgc atgattgcag gactggaaca tcaggacagt
    12781 ggagatattt acatcgatgg aacatgtgtc aatgaacttc tggtaagaga gcgcgggatc
    12841 ggatttgtgt ttcagaatta tgcactgttt ccttatatga cggtatttga caatgtggca
    12901 tatggactta aggtccgcaa ggaagataaa aaagtcattg agaagagggt aaaagaactt
    12961 ttagagcttg tggatctgaa aggactcgaa aaacgttatc cgacgcagtt gtccggcgga
    13021 cagagacagc gtgtggcatt tgcgagggca cttgcaccga atccgcaggt actgctctta
    13081 gatgagccgt ttgcggcgat cgatgccaaa gtaagaaagg agctgcggaa ctggttaaaa
    13141 gatatgatcg gaaagattgg tatcacgagt atttttgtaa cacatgatca ggatgaagcc
    13201 gttgaggtgg cggatgagat cattgtcacc aatcagggaa gagtagagca gatgggaacg
    13261 ccgacggaga tctataaaaa tccgaaaaca ccgtttgtcg cacagtttat cggggaatcg
    13321 gcggtgatta cagattatga caggctgaaa ggttttcatt tatatcaggg atgtgacagg
    13381 gcgattatcc gtccggagtt tgtaaaggca gtccggttcg gaaccgaaaa aagattccag
    13441 agtctgtatg cggaaggtat tgtggagcag gttgcgtttc gcggaaactg cttagaactt
    13501 cagatcaatg tcaatggcat tttattaaaa acgatacagt cctttgcgga agaaccgttc
    13561 cagaaagggg aaaaggtaga ggtcattgta taccggcttt atgcggtgga tgagaaagaa
    13621 gcgcacctga tacaaaatga gggcttacag gaaaatgaaa tgttttacat ttagcgaggg
    13681 aggattcgtg atgaagaaag aaaaaagaat catacaggta attgtaaaaa gtggtctgat
    13741 cacatgggtt ctgctgcttt tgatctggca gatcggttcc ctgttttaca gtgatgattt
    13801 tctgccggga cctttcacaa cctttgcagg ggcaggaaaa ttagtggcga gcggagatct
    13861 tttccgggat attctgatca gtatgcagcg tgtattaaaa ggctggctac tagggatttt
    13921 gtttgcgatt ccggcgggac tctgcatcgg gcactttaaa aagatcgggg cgatttttga
    13981 accattttta aactttttcc ggttcgttcc ggcgatcggc tttatcacac tgtttctgat
    14041 gtggttcgga gtcggcgaaa aatcaaaggt ggcactgatc ttttatgcag tgatctttcc
    14101 ggtaatgatc aatacgatcg caggtgtacg gacggtggat gatgcactga tcgaggcttc
    14161 ggaatcgctt ggtgcagacg gagcgaaaac tttttttacg gtgatcatcc cgtctgcagt
    14221 tccaaatatt tttaccggtg tgcgtttagg attaagcggt gcgatcatct gcatcgtggc
    14281 ggcagaaatg ttagcagcct ccgaaggaat cggttatctg atctatacat caagacttta
    14341 ttataaaaca gactggatct ttatcggtat ttttacactg ggtatcatcg gctttctcgc
    14401 agacagactg ttacagtttg tgggaagaaa agcattgaaa a
//
