LOCUS       c00010_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PPLACMOB_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 01:24:24
            Original ID  :: gnl|Prokka|PPLACMOB_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 68096
            Orig. end    :: 81785
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[78096:81586]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(337..1044)
                     /locus_tag="ctg10_57"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
     CDS             1167..2777
                     /locus_tag="ctg10_58"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2841..3359
                     /locus_tag="ctg10_59"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMKKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLAEPDEDGAHPGA
                     LRENEEAGQ"
     CDS             3304..4233
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_60"
                     /sec_met_domain="adh_short_C2 (E-value: 1.1e-74, bitscore:
                     243.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRTPVHSGKMKRPDSSPPPRFSPLFFHSRHALSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVAHRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4257..5462
                     /locus_tag="ctg10_61"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             5476..5676
                     /locus_tag="ctg10_62"
                     /transl_table=11
                     /translation="MIIALRTEQSADHAETEHVTREALWNYFVPGCNEHYLLHIMRVSP
                     SFISELDTVAVHGSRIVGKHR"
     CDS             5729..6166
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_63"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3e-08, bitscore:
                     26.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPIAVLPEYQRRGIGRRMIGYTRNRAREMGFRAIFLYGDPDYSS
                     HCGFVPAETLGIRTADNRYAAALQVCALQRGSLSGLKGRYVEAAVYHMDEKRAAEFDRH
                     FPVKKKLSGIASQKRFQQIAAMRRKPDTAPCPRKSRTFRRA"
     CDS             complement(6268..7008)
                     /locus_tag="ctg10_64"
                     /transl_table=11
                     /translation="MKKTLTLLIAMGSFAVSSEAATVFNYYTPGTDNCNSTIHGFYLSL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMGLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPSDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7303..8010
                     /locus_tag="ctg10_65"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSDLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg10_66"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg10_67"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg10_68"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_69"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_70"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.8e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12723..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_71"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.5e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 gaagaacatc gctatcctcg ccatcgccgg cgccgcttgc ctggtcgctt cctgctccca
       61 gcagcagcag caacagcaaa ccaccgctcc tgctcccgct ccggttgtgc aggccaaggg
      121 caagtaagtt tgcagcgggg ttttgccctg caacactagc aaattatcca attaatccgc
      181 actcggtgta cgcactgagt gcgtttttat ttgccctgag tccggattcc ctccgccatt
      241 tgccgattcg ccgggatttt ccttaaaaac ggcggatacc gcaaaccgcc gcggcgcagc
      301 accgtgtgcc ggttcctgcc ggatcaggct tcccctttat tcagcggccg ccttcgcctc
      361 attctgctga tcggactgaa atatccgctg aaccagcatg gggcgtttcc tggcccaccc
      421 gggccagacc aggtgatgtt ccatgccgta ggaatggccc tccggaaagg ccttggaaac
      481 aaatggttcc cgccagtcct cctcccattt gccgccttcc cggtccttct gggtcagcgt
      541 caccagatgc ccgcagttct tccaggcatc cagaacaatg gagccctgca atcccttccc
      601 cgcggcattg acatacacgc aactgtgctc cctgcccgtt ccacggtctc gaatcgtcag
      661 ccctatgcgg aaatacttca cggggcggcg gcgcaggtcc cggtacaaat cctgctggac
      721 ctgccagcac agccccctgt cgcgcaggtt ggaattgacc agaatattgt tcagccagcc
      781 aaacagcaca gtcctgttgt cccgggcaat cgctgcggac tggaccacgg ccgtgtccgc
      841 cagccacctg gcctccgctc cggcagcggg aagagaggcc tgatccggcg gcagcagcgc
      901 caggaaggca ttagccagcc cggacatttg ctgctgcacg taaggttgtt gtatataatc
      961 ctccgccgga ggagtacagc aggaactcca tccgcacaaa agggcggcag caagcaaaag
     1021 cctgaatgtc tgcgtggtcg gcatggcgcg ccaaggctag cagactacgc gtaaaaatcc
     1081 agtaaagctt tcaaaaatgc ctgcctccgc cctgacggct cttgccttcc cctttccatc
     1141 ccggtagaat acatcctctc ttcaccatgc tgacgatcaa aaatctcaca aaatcccacg
     1201 ccggacggac cttgttcagg gaaacggaaa tgaccattaa ctggggggaa cgggtggctc
     1261 tggttggccc caacggagca ggcaaatcca ccctgttccg catgattctg ggagaagaca
     1321 cgccggacga aggctccatc agcatggatg aatacgccat cgtgggctat cttccccagg
     1381 aagccagcga accgaaggat gaaaccgttc tggaaatcgc cctgggcatc acgccggaaa
     1441 tggaacaggc catccacacc atccggacgg cggaaaacgc caacaaaacg gatacgccgg
     1501 aatacgcgga agccattgac accttcaacg ccgccaacgg ttaccagctg gagcccaaag
     1561 ccaagaaaat tctcaaaggg ctggcctttc gggaaagcga cttccaccgc cccgcccggg
     1621 aaatgtccgg cggctggatc atgcgcgcgt acctggccaa gctccttgtc ctggagccgg
     1681 acctcctgat gctggacgaa cctaccaacc acctggacct cctgtccctg ctgtggctcc
     1741 agcgatacct gaaaaactac cccggagcca tcctgatgat ttcccacgac cgggatttca
     1801 tggatgagct ggtggaaagc gtgtacgaca tcgacaacga agaactggtg gaataccgcg
     1861 gcaattactc ggacttcctc caacaaaagg acgtgcgctt cgagcagctt caggcggcct
     1921 accgcaacca gcagaaggaa atagcgcaca ttcaggaatt tattgaccgt ttccgctcca
     1981 tcaattccaa agccgggcaa gtccagagcc gcatcaagca gctggaaaag atgaaaatca
     2041 ttcaaaaacc ggtagcccgc aggaaagtat ttaaattcaa cttcccccag cctccgcgca
     2101 gcacccagaa agtcattgag ctggaaaaag tctgccaatc ctatggcgac cgcagggttt
     2161 atgaaaacct ggacctgctg gtggaacgcg gggagcgcac tgttcttgta ggcccgaacg
     2221 gcgcgggcaa atccactctt ctcaaaatcc tggcgggcat catccccatt gactccggac
     2281 aacgcactcc cggtaccacg acgcgcatcg gctacttctc ccaggcgcga acggaaaacc
     2341 tgaatccgga aaataccgtg ctggaggaaa tcatgaaatg cagcgctgaa atccgggagg
     2401 aagaagcgcg ttccatcctg ggttccttcc tgttccggag gctggatgtg gaaaaacgcg
     2461 tcagcgttct ttccggcggg gaaaaatcgc ggctcagctt ggtcaaattc ctggtggatc
     2521 cgcccaacct cctgctgatg gacgagccga ccacccacct ggaccttttg tccgtagaag
     2581 ccctggtgca ggctctgaag cattatgaag gaacactggt cttcatctcc cacgatgtgc
     2641 acttcatccg ttccctggca caaaaaaccc tgcatgtgaa ccgggggacc atcaccgcct
     2701 acgcaggcgg atatgactac tatctggaaa agtcaggcat tctggacgat gaaaaaggcg
     2761 gcatcacggc ggaataaggc tcttttttca gtttcccctt tttccttgcc gtggatttca
     2821 tcctgcctta aaagaacagg atgaaggctt ttcttgttcc tctcttatat tctgcgcttc
     2881 tgtccggagc ctctcttgca tttggtgaaa cggccgccgg aacggcttcc cccgcagcag
     2941 cggctccggc ggaaaaaatt ccttccgcgg aatccctgat caaccaggcc ttttcctttg
     3001 ccatcaatat ccagcagacg ttggcaggcg ttcaggacaa ggaaagcgcg gacaacgccg
     3061 tcaaaacgct gcaggacatt cagaaggaca tccggcattt cctccagctt caggataaat
     3121 tgaacgatgc ggaaaaggag aaagaagacg ccttgataga aaaaatgaaa aaacgaatgg
     3181 aaatgctgga caaccgctgc aggcaggaag gcaaacgcct gtttgaggcc cgctattacg
     3241 gttccgccgc cttaaaggac attttggaaa attcggatga attcagcgac ctggcagaac
     3301 cggatgaaga cggggcgcac cccggtgcac tccgggaaaa tgaagaggcc ggacagtagc
     3361 cccccgcccc gtttctcccc cctctttttt cattcccggc acgccctttc cccgtatggg
     3421 ttcctgcgcg gccaagtcca tttcaagctt gccggaaccg tgaaaaacgg gtttactgtg
     3481 ggcagcatgc aaaagttagc aggtaaaaca gccatcgtta ccggcgcggg ccgcggaatc
     3541 ggcaatgccg tcgcgcaccg cttcgcttcg gaaggagcca gggtcatcct gatcagccgc
     3601 agtccatcca gctgcggggg ggccgcagaa gaaatcaaca aggaatttcc ggattcctgc
     3661 aaggcctacc cctgcgacgt agcggattac gcggccgttc aggaaaccat ggccgccatt
     3721 ttgaaagact tcccgcagat tgacatcctg gtgaacaacg ccggcatcac gcgggactcc
     3781 ctgatgctcc gcatgaaaga ggaagactgg gatgccgttc tggacaccaa cctgaaaagc
     3841 gcgttcaata cggtcaaggc cctccagcgc gttctcatga aatccccggc cgggcgtatc
     3901 atcaacatga gctccgtcat cggtctcgtc ggcaacatcg gccaggccaa ttacgccgct
     3961 tccaaggcgg gcctcatcgg tttcaccaaa tcactggctc aggaattcgc tccgcgcaaa
     4021 gtcacgtgca acgccattgc tcccggcttc atctccacgg aaatgtccaa tgccattccc
     4081 gacaatctca aggaagaaat cgttaagaaa atacctttga aagaacaagg ttccgtggaa
     4141 gatatcgccg ccctgacggc cttccttgcc tctgacgatg cccgttacat caccgggcag
     4201 gtcattgcct gcgacggagg catgacgatg tagggcattc cggttttcac cattccatgc
     4261 gcggcatttt ccttgtttcc tgctttctgg gaggaagcgt cctgctggcc gggtgccggg
     4321 aagaaaataa ttccccccgc ccggccacgg aagatgccgc gcgcattacc agcgcacgcc
     4381 aatggggaga aagccgatcc gcgctgcaaa aacgggaact ggaccgcgct gccggtcctg
     4441 cccttcccat tccggatgac ctgccgtccc gggagctggt cggcacgacg cgccaaatcc
     4501 atcagctcat tgaagcttcc ggaaatccgg cacgttttga atcctacacg gaaacggttc
     4561 ccgcggcggg agcttccctg cgcatggtcg ccataccggg aggaacgttc ctcatgggga
     4621 gtcccgcgga agagccgcac cggaaaccgg acgaaggacc gcagcataaa gtgagcatct
     4681 ctcccttctg gatctcggaa acggaaatcc cctgggaact ttatacggcc ttcatggaaa
     4741 acgggcgtcc gcgcgccaag gacggtcagc ttctggagga acagccggat gacgaactgt
     4801 gggactccgt tacgcagcct accgccccct acaccgccat gaacctgggc atgggccacg
     4861 gctatgaaca cggtctgccc gccatctcca tgtcccacca cgccgccagc aaattctgcg
     4921 aatggctgag cgcccagacc gggcattact accgcctgcc cacggaggcg gaatgggaat
     4981 acgcctgccg ggccggctcc cccggcgcct attcttacgg aaacggggaa gcctctctgg
     5041 accagtacgc ctggtactgg aacaactcca atgaccgcta ccagaaaaca ggctctaaaa
     5101 aaccaaataa gtggggactc cgggacatgc acggaaatgt ggcggaatgg gttttggact
     5161 cttacgttcc ggatgcctac ggcaaacgga gcggcttgcc cgcgaaagac cccttggtca
     5221 tcatccccgg cgcccctcac atcgttcgcg gcggttcgtg ggaagacgac ccggacagcc
     5281 tgagaagcgc tgcgcgccgc gccagcaccc ccgcctggaa ccgtcaggat cctcaaaacc
     5341 ctaaaagcat ctggtacctg acggacggag gcatgatcgg gttccgcgtg gtgcgcccca
     5401 tgaacattcc ggacgttatg acgatgcacc gcctctggaa tttctccaag ggggagccgt
     5461 aaagaacaac ccttcatgat cattgcatta agaacggaac aatccgcaga ccatgccgaa
     5521 acggaacatg tcacgagaga agcgctctgg aactatttcg tccccggctg caatgaacat
     5581 tacctgctcc atatcatgcg cgtcagtcct tccttcatct cggagctgga tacagtcgcc
     5641 gtccacggca gccgcatcgt cgggaaacat cgttgatgca acgtccgtca tcagggcaga
     5701 cgatggaaaa gaatatgaag tgctgggcat ggggcccatt gccgttcttc cggaatacca
     5761 gcgccgggga ataggacggc ggatgatcgg ctacaccagg aaccgggcgc gtgaaatggg
     5821 cttccgtgcc attttcctgt acggcgaccc ggactactct tcacactgtg gattcgttcc
     5881 cgcggaaacg ctgggcatca gaacggcgga taataggtat gcggcggccc tccaggtctg
     5941 tgcgctgcaa aggggttccc tatccggcct gaaaggccgc tatgtggaag ctgccgtgta
     6001 ccatatggac gaaaagcgcg ctgccgaatt tgaccggcat tttccggtaa agaaaaagct
     6061 ttccggtatt gcgtctcaaa aacgtttcca gcaaattgcc gccatgcgga gaaaaccgga
     6121 tacggccccc tgcccccgga aatcccgtac cttccggagg gcatgaatcc cgcatgcgga
     6181 tgagtaattc ttcctctctg gatataaaaa acaagagctg ttccgcaaga acagctctca
     6241 tccgccgatt tttcgccatc aggaagctca agccctgcgg cggcgcatca tcagcgcggc
     6301 cagtcccagc aggcccaggg aaaccgtggc tggttccggc accatttccc ctcggatttc
     6361 cgtgaaaatc ggagataata agctgaaagt attggttccg ttggctcccg taataacaac
     6421 agaatcacta ggcgctccct cggcgtcata atggccgcgg atgccgggag cagtcaatcc
     6481 gccgctgatc gttacggtat ctccttccgt gttagcagta ggggcggctg ttccccccgc
     6541 agcatataaa tacgttttag acgtatcctg catcaagccc atcacggact ggctcacggc
     6601 caggaagcgg tatgtcaatg ccgcgtcaag aagcagggga gaaccatcca gggaagaaaa
     6661 actgaacgtc agattaatcc ctgctgcagt agttcccgta ttggtgctcc agccgatgac
     6721 cgaattgtcg gagccattca gcaccaggaa gccgtaagtg acattagcgc ccaaattgtt
     6781 ggcggctccg cgcagcgtaa aactgtccag tctgatctct ccggacaggg aggagggaga
     6841 agaggaatcg gaaggagcca gggaagaaga ccccaggcta agataaaacc catggatggt
     6901 actattgcaa ttatccgtac cgggagtgta ataattaaaa acggtcgctg cctccgagga
     6961 aacagcaaag cttcccatcg cgattaaaag tgtcagtgtt ttcttcatat ttattattcc
     7021 ttttggatgg caacttgtag cgaatttgga attccccaat cggatttgga atccgtcaag
     7081 taatgaaaaa gaggccaaat caatcatgaa accaatgaat aacaaagact gacccgtcat
     7141 cttgacaaaa ggaccagaga tattaaaaaa tcattatttt caatgaatta taaacacaat
     7201 atactaactc ttaatatttt taattgcttg cggattccaa attcgttatt caagcacaag
     7261 tacatacatt gaatcttgca tcattttatt aagatactga ccatgaataa attattatcc
     7321 accctgattc tttcggccgg catgagccta agcgctaccg cggctaccgc tctgctggat
     7381 agctccatcg tgggatattc ggactttgcc tcccaaacgg cggatttcgg cacccggaaa
     7441 gattccgttt ccatcacgtc tgacgacagc aatctgacgt tatccgggat aaccttcaac
     7501 ggatacggtg ccaacaaccg cgacgttatg tctgtgacga tggttcttga cctgtccaaa
     7561 atcaacactc cggacgccta taccgctctg tttaacgcca aaaacagcag tgtaagctgg
     7621 ggcgtgggcc tgaacacgga ccggaaactc cagggattat ggaacaacac ctcatacaac
     7681 gggcccgtcg ttgacacccc gctgggcacg gaaggttccc tgaccatttc cgtagtcacc
     7741 ggagatcttg gcacccgcat ctattttgga gacagcgcta cgtactattc caacagcgac
     7801 ctgaaattcg gcaaccagca aattgatcag attctcatgg acgcaggact ggctgaatcc
     7861 attgaacagc tctacattca cgactccctc ctttcccagg aacaagttgg tcaactgatg
     7921 agtgaaatcg ccagcatccc ggaacccgcc acggcttccc tgggcctgct gggactggcc
     7981 gcgctgatga tgcgccgccg cagggcataa gcctgtaccg tccgcctccc tatattcaaa
     8041 ggccggctca caaaatcgtg agccggcctt ttccttatcc gttcaaacat ctgccggaaa
     8101 aaacaggggg ggaagaagct tccatttgct gcggtaccct cacggccagc acttgacggg
     8161 gaaatggcat tcaggctccc ccgggagggt catttcaaga gcttccggcc ccgccccact
     8221 tccgtacacg cccctttttc ccatgccggg acagccggaa ccggagcatg caaagcccgg
     8281 cttccctcag catccggaac agcccatcct ttcagcaatc catttccccg cacggtccgg
     8341 atcgctgcgg tttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttccctt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcggccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgttggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggt tgcaacgtca ctgccgccta caaagcctac aagcgtggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaaaggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaagaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggttgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcttggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gatggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggcttcggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagca
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga gaccgtactt ggaaatgccg
    13681 gacgaaacc
//
