LOCUS       c00098_gnlPro..        12858 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BCAEIECC_98.
ACCESSION   c00098_gnlPro..
VERSION     c00098_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:28:58
            Original ID  :: gnl|Prokka|BCAEIECC_98
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12858
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12858
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[210:6196]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      211..6196
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12858
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12858
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(211..1257)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_1"
                     /sec_met_domain="IlvN (E-value: 9.8e-49, bitscore: 154.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRKGGKTWEKAVADGWVPGETLFDIEEACEKATIIQYLLSDAAQI
                     EVWPRIKKYLTPGKALYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQG
                     RGLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQG
                     LLLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWM
                     GPFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVV
                     RKLRPENN"
     CDS             complement(1299..2030)
                     /locus_tag="ctg98_2"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSPG
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(2067..2621)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_3"
                     /sec_met_domain="ALS_ss_C (E-value: 9e-19, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLHEKHV"
     CDS             complement(2634..4334)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNKCDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(4361..6196)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg98_5"
                     /sec_met_domain="ILVD_EDD (E-value: 1.3e-218, bitscore:
                     715.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAYRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             complement(6567..8030)
                     /locus_tag="ctg98_6"
                     /transl_table=11
                     /translation="MKKQYIYFLSLFVMCLAACSNPVDPTALNLDSANINRLIPFRGEL
                     NNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDYMAEMIVSVNRMGDGEETELV
                     LSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKIGKPGKQDDFNVYLYSLEVTR
                     PETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQSGEPLAYEDAVNNFDVDRFA
                     RTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTKRDLVADLSDALGKYGIRLIL
                     YYHVGHGDKEWWDKQHYTRDNAGDLFTNVEKIVGEISQRYGNRLAGLWMDDGIGYYPNG
                     ASFEKIAKAAKSGNKELAICFNSWILPKLTDFQDYYAGELGLSLASAGVNDPSLPLDGD
                     GLFHGGPQDGLQATFSGTLEPGDWTHIYKDSIIGDPVLSIDELTQVVKESNKRKNLPMI
                     NVRIYQDGTISPKSYALLKELNNRISKGE"
     CDS             complement(8103..9545)
                     /locus_tag="ctg98_7"
                     /transl_table=11
                     /translation="MKRMKTLIKNILLAVPVILSASCSDWLEEDPKTFISPSSFYQTVE
                     DFDGALKGLYPQGQNLNLTEVFADYNDKPESAEQVGDIWANNPGYGFYAFRNAWSGPYS
                     TIKNANMILESIEDKDFTAETKNRIIGEAKCLRAWSYFTLVQFFGDVPLRDKVVTSDAD
                     VAIDRMPQADIYQFIFDDILDAEQKLPEEAQDMGRVNKWVVKAIMARIYLTSAGFPMNQ
                     KENYAKAKEKALEVINSGQYSLMPTFDKVFKTERYTAETIWAQLFSAPDSYSGMHNESS
                     PIGSQTALYLPTDAFIASFDKGDMRKEWGIKPEYVNVKGNKVIARTYYNKYINEEYLEQ
                     ELPASNTNILTWQTQLIRLAEMYLIAAEAENEINGPAGAYQYINAIRKRARVDQNDPTN
                     VPDLSGLSQDQFREAVLLERQHELYEEGFAWYDLKRTQTFDKVQKARGSRLNVPIGAYN
                     NTWLIPDTEILNNNIPQNPDYR"
     CDS             complement(9551..12799)
                     /locus_tag="ctg98_8"
                     /transl_table=11
                     /translation="LFITALSSISLFSYAQHQQVRLTGSNVTLKTAFKQIEQQTKLFVD
                     YNTQEVNDSRVLTKLPKNSNVKEVMEQLLEGSGCSITFSNGHIIINKQARTVSSTKNIS
                     GVVKDETGEPVIGANVVVKGTTNGTVTDMNGRYSLEVPEGGVLQISYIGYNTQEVKVGS
                     GDVVNVSLREDSEALDEVVVIGYGTVKKSDLTGAVGSVQMKDVSQVGITSADRALQGQI
                     AGVQVNARTGQPGESMMIRVRGSNSLAGGNEPLYVIDGMPVEKMNSDINPEDILSMEVL
                     KDASSTAIYGSRGANGVVMITTKRGRTGDTVLEYNGYVGVSSLRKKLDLLGKDDYIAMV
                     NEVSQNDGNGIAITPEQAAMLPNNDWQDLAYQTALTHSHQVSVSGGTDKTKLYSSLNYM
                     NQEGIIKGSDYNRFALRINGDQKLARNLSLNASIAYSYGTQNTANSNADGWGAIAYTAM
                     VMAPIQEIRDADGKYTNFSGTPWGGTNPVGMAELYKNKTVNSRLLANMSLIYEIIDGLT
                     FRVNAGAEVNAGSSDRYIPIGLSAGGKLDGDASKSKSNYYTIINENILTYDKRFNKNHA
                     LNLMGGVTFQTYQYNDLGGSGTGFLRDVYETNNLGVASTPGTPSSGYSDYRMASFLGRA
                     NYNLMERYLLTVTARYDGSSKFSKNHKFAFFPSAALAWRLSEENFMQDIDWLSNLKLRA
                     SIGQTGNQSISPYQTFARLGTSGPIFGDGKDIGFGLSSMANDDLKWETTTQTDIGVDFG
                     FFSNRLNIGFDYYWKQTRDLLYNATLPPSSGYSSMLRNLGRIDNKGFEISINTINMKGK
                     VNWTTNLNITSNRSIVKDLGSDVYGNKIQRIDAPIGGGNWFPLFVGKAPFQLYGYEIEG
                     IYQTDEEARLNGEATKKAGDYRYKDTDGKAGITTGDKTIIANTQPKFTFGLTNIINWNN
                     FELSFLLIGSVGGDIVNEFNKSITNIGGTWNIRKDVWENHWTPENPNAKYARASVATKD
                     YLAFGDPSSVWVENGSYLRFKDIKLAYTLPSQWFAGSRKPNISVYLSGQNLITITSYSH
                     YDPEASWTSSAVNGWDRGVYPSAKSFTLGLQVKF"
ORIGIN
        1 attttaacca ccatttaatt gattttttta tctaaaatcc acattcaaac aatgacatac
       61 atattgggat gaaaaatcaa taacagttgc aatcaaaaac attttttaac cattaacgca
      121 ttacataaac cataaaaaaa cggcaacccg aaaagccgga ttgccgtttt tatatcacaa
      181 aatgtttaac tattaatgta tcaccattta ttagttgttt tcaggacgaa gtttacgaac
      241 aacagcacct gcacgccaca tttcactttc gcgaagagca gccagttctt tttccagacc
      301 ttcacgatag tcaggcttgc tgtttgtgtc gatagaacgc tgtgcttcgt taccgcaggc
      361 aacttcgcta tacaacttct ggaacaccgg ttttgtagca tcgtggaacg ggcccatcca
      421 gtccaaagca ccacgctgtg cagttgttga acagtttgca tacatccagt ccataccgtt
      481 ttctgcgaac aacggcatca atgactgagt cagttcttct actgtttcat tgaatgcttc
      541 agaaggttcg tgaccgtttt cacgcaaagt ttcgtactga gccaacagta atccctggat
      601 agctcccatc aaagtaccac gttcgccggt caggtcagaa taaacttctt tcttgaatgt
      661 tgtttcaaac aagtaaccag aaccaacacc gatacccagt gcaatcacgc gatcccatgc
      721 tttgcctgtt gcatcctgga agattgcgta gcttgagttc agaccacgac cctgcaagaa
      781 catacggcgc agtgaagtac ctgaaccttt cggagcaacc aggattacgt ctacatcagc
      841 aggagggatg atgtttgtac gttctttgta agtgataccg aatccgtgag agaaatacaa
      901 agccttaccc ggagtcaggt attttttgat gcgcggccaa acttcaatct gagcagcatc
      961 tgaaagcaga tactggatga tagttgcttt ttcgcatgct tcttcgatat cgaacagtgt
     1021 ttcgcccggt acccaaccgt cagcaacggc cttttcccag gtcttaccac ctttacgttg
     1081 tcctacaatt acgttaaaac cattgtcgcg caggttcagg ctctggccag gaccttgtac
     1141 gccgtaacct attacagcga ttgtttcgtc tttcaatact tctcttgcct tttccaacgg
     1201 aaattcttcg cgggttacta cgttttcgtc aacgccgcca aaattcatta ctgccatttt
     1261 ctttttacta ttaaaatgta tataaaataa tttgtttttc agatccaggt aacggcagcg
     1321 cggctgatgg ctttgccgtc gttacagatt gccatattat atttaccggg ggatacttcc
     1381 tggttatgga gagtcagctc catcccatac tttccttcgg actgataagc tatttcgaaa
     1441 cggcttatct ctttttctcg gaacaggctg atatcgaaca agtcgagcag gtgttccatg
     1501 tatttgatac tgttcaggtg gccgtttacg tccaggtcac tgtacttcac acggtaaggt
     1561 tcgccggaag tgttgttttc caccggagca attttacccg gtttttcaat cggacaggga
     1621 cggtcggtga tataagcact caggccctcc acatcgagca aggtcgggcg gcgggtttcc
     1681 atatcgatag ccgcccagat agagcgggca aagccaaagg tcttgccttc accgttcacc
     1741 agttcaaagc aacggctggt aaacaactta ccgacctcat ccacccaggt atataaagtt
     1801 acggattcag acatggcagg ataagaagtc atctcgatag ccagacggga aagaacccag
     1861 gcggtatgcc tttcggtcat atcgttatat ccgaatccac ggtcggcggc atggcaagaa
     1921 gcagcatgca acaaataagt tccgatcata gggattgtaa tacgtccccg gaagtccatc
     1981 agataagact ctgttacgaa atgaaattct cctactttgt tcttctccat aatttacttt
     2041 atttacaaaa tgtttccttg ttgttctcag acatgttttt catgcaactt cttttccatt
     2101 gcagataaca tgtcgctcag acgttctacc ttactcttcg ttatagcaac gcgtccggaa
     2161 cggataaatt gcaggacacc gatcgtctca ctcaattctt taaacaaagc ctgtgtctca
     2221 tcataatgac cactcttttc caacaccaca caatcctcat tcatttcaag gatacgggca
     2281 ttgtacttac ggatcagatc ctcaaccgtc cccatcttga taaagagttc ggtactcagt
     2341 ttataaagag caatttcctg gtaaaccagg tcttcatccg tattataata ggctttcagg
     2401 atatccacac gcttgtcgat ctgttttacg accttgtcga tcgtatcctc gtcggcaaag
     2461 gtagtaattg taaacttatg tattcccttt atagcagagg gagaaacaga aagcgtctca
     2521 atgttcagtt gccggcgcgt aaagataaca gttatctgat tcagaagacc aacagtgttt
     2581 tccgaaaaga taataacggt atataattgt tttgtattca tagtttctcc tccttactta
     2641 tcacccaaaa tcatgtttgt cacgcttcct ccggccggaa ccatcggata taccatacca
     2701 caagtttcca cattggcaac caacatatag gcaccatcgt gattcaacat ttcagcaatc
     2761 gcctcatcca agtcttcccg tttatctacc gcacgggaag caataccaaa agccttggct
     2821 atcgctacaa aatccggatt cttcatgatg gtattcgaat accgttcgtt gaagaacagc
     2881 tcctgccact ggcgtaccat tcccaggaaa ttgttgttaa gaacgatgat ctttacattc
     2941 agattttcct gcatgatagt tcccaactcc tggatagtca tctggatacc accgtcgccg
     3001 gtaaagaaac agaccgtacg gtcaggcgct cccagcttcg ctccaatggc ggcgggaagg
     3061 ccaaagccca tcgttcccaa acctcctgaa gtaactacgc tgcgtgtttg tttatatttg
     3121 aaatagcgaa cacccatcat ctggttctga cctacatccg taaccagaat cgcatcatta
     3181 tcggttgctt cggaaacctt acggactact tcgcccattt ttagttggcc ttcggtagga
     3241 tagagttctt tttctattac cttattatat tcctcttttt catccggttc gaattcagca
     3301 ttccattccg gacgcttccg ttcttccagt aaagccgtaa tcatcggaat cgtatgcttg
     3361 gcatttccca gcactttcac gtcgaccggc acattctttc cgatctccga attgtcgata
     3421 tccaggtgga taatctttgc ctgcttggca taagtcttca ggtcgccggt tacacggtca
     3481 tcgaaacgca taccgatagc aatcagcacg tcacatttgt ttgtcttgcg gttcggtccg
     3541 acatttccat gcatccccaa cataccttta tttaatggga agtccgaagg taatgcagac
     3601 aagcccaata cggtagaacc ggctggtata tcgtttttca acaagaattc tttcagttct
     3661 tcttcagctc ctcccaggat aaccccctgc cctaccagac agaatggctt tttggcatta
     3721 tttatcaatg aagcagccgc ctcgatacgt tcctccctga tatccggttc aggctggtaa
     3781 ctacgaacat aatccacttt ctgatactca taatctacca aacccacctg tgcatctttc
     3841 gccaaatcca gtaccacagg tcccgggcga ccggtcgatg cgatatagaa agcacgggaa
     3901 acggcccaag caatttcttc cgggcggcgt atctggtaag cccatttggt aatcggttgt
     3961 gtgataccaa ttacatcaac ttcctggaaa gcatctgttc caagcagcgg agacggaacc
     4021 tggccggcaa tcaccaccat cggtgtactg tccatcagcg catcggcaat accagtgatg
     4081 gtattggttg ccccgggacc cgaagtaacc accgttactc ccacttttcc ggaaacacgg
     4141 gcatatccct gtgcagcatg tgttgcacct tgttcgtggc gcaccagaat atgttttaac
     4201 tgatctctgt aatcgtataa actatcgtaa attggtatcg cctgcccacc cggataaccg
     4261 aagatagtat ctactccttc agcgatcagc gctttcagca aagcttccga accggttatc
     4321 ttttgtttgt ccatctctaa aatatagtat ttggtgttta ttaatcttct actattcgta
     4381 caccgccctt atcggccgaa gcaaccatct ttgcatatgc tttcagtgct ttcgataccg
     4441 tacgttggcg gaaaggaggt gtaaaggctt ttgttccgcg agcttcttcc gcttcacggc
     4501 gtttggccag ttcttcgtct gtcaccttta catgtatggt tctttcggga atattaattt
     4561 cgataatatc gccgtctttc actaagccaa tcgctccgcc tgcagccgct tcgggagaaa
     4621 tatgtccgat tgacaaaccc gatgttccac cgctgaagcg tccgtctgtg attagcgcac
     4681 attctttacc caggtgttta ctctttatat aagaagtagg atacaacatt tcctgcatac
     4741 ccggaccacc cttaggacct tcataggtga taacgacgac atcgccggag acgactttat
     4801 ctttcaggat accttcgcaa gcggcatcct gcgaatcgaa tactttggca gggccggcaa
     4861 aacggaagat actttcatct accccggctg ttttaaccac acaaccgtcc tgtgcaatat
     4921 ttccatacag aacagccaga ccgccgtctt tcacataagc atgttccaca tcgcggatac
     4981 atccggttgc acggtcggta tccagttctt tataataact ttcctgcgat ccgagcacca
     5041 ggttgaaacg gtaggccgga gcacttttat aaatattgat tgcttcttcc gttacattta
     5101 cagaggtaat gcagtattgg tcgatagcct cattcaaagt cagaccatcc gcacgtttca
     5161 cggagccgtc caccagaccg gcttttacca gctcattcat aataccgatg atacctccgg
     5221 cacggttcac atcttccacg tgataagaac aactcggagc cactttacag ataaccggtg
     5281 ttttgcgtga aagcatatcg atgtctttca ttgtaaaatc gacttccgct tcatgagcca
     5341 cggccaacag gtgaaggact gtattcgtcg atccccccat ggcaatatcc agcgacatag
     5401 cattcagaaa ggcctgccgg gtggcaatac tgcgaggcaa tacggaatca tcgccgtcac
     5461 gataatattt aaaggcatta tcaacaatca tcttcgccgc ttttttgaac aggcgggtac
     5521 ggttggcatg tgttgcaaca actgttccgt tgccgggaag agccaatcca atcgcttcgt
     5581 tcagacagtt catagagtta gccgtgaaca taccagaaca gcaaccgcag gtcgggcaag
     5641 cggaacgttc caccttttct acttgttcat cgctgataga atcgtcagcc gcttcaatca
     5701 tggcgtcgat caaatcgagt gcacgtccgt ccagattacc ggcttccatc ggaccgccgg
     5761 atacaaagat tgtcggaata ttcagacgca tactggccat cagcataccc ggagtaatct
     5821 tgtcgcagtt actgatacaa accattgcat cagccttatg cgcattcacc atatattcca
     5881 cactgtcagc aatgatgtcg cgggaaggca gagaataaag cattccgtcg tgtcccatag
     5941 caataccgtc atcaatagcg atcgtattaa attctgcggc aaagcaaccg agcttttcga
     6001 tttccgcttt tacctgctgt ccgatctcgt gtagatgcac atggcccggt acaaactggg
     6061 taaatgaatt cacaatggca atgatcggtt taccgaactg ttcttctttc atgccgttgg
     6121 cacgccataa tgcacgggct ccggccatac gtctgccttc tgtgctatag gagcttctta
     6181 acggattctt catcatatct gtttttatct tttagtcaat aaaaaagccc ttctctatat
     6241 ggagaaaggc ttaagaaata tcttttacga cttcacaact tcttacacac ctttctcctt
     6301 acctactaat gactagaagg accaccacga gaataatatg taatacattg ttcatcatct
     6361 tttcttatcg tctttatttt gtttgacgct gcaaatgtag aataataatt tgtacgagca
     6421 aaggatttaa aagaaaaatc ttactttttc tttcatttat caagaaaaga gggcggttca
     6481 tcttgcattt taacagataa ccagccctca atcaattgaa ttcttatttc tgagcctcca
     6541 ttcgcttcat attcgataat ttccggtcat tctcctttac tgatacgatt gttcagttct
     6601 ttcaacaaag catacgattt cggagaaatc gttccatcct gataaatccg gacattaatc
     6661 atcggaagat tttttcgttt gttagattct ttcactacct gcgtcaattc gtcaatggaa
     6721 agaacaggat caccgataat ggaatcttta taaatgtgcg tccagtcacc cggctccaat
     6781 gttccggaga aagtcgcctg taagccatcc tgagggccac cgtgaaacaa tccgtcccca
     6841 tccaacggaa gagaaggatc gttaacaccg gcactggcca aagacaaacc cagttcgcca
     6901 gcataataat cctgaaagtc cgtcagtttc ggcaatatcc aggaattaaa acaaatcgcc
     6961 aactccttat ttccactttt ggcggcttta gcaatctttt caaacgaagc gccgttagga
     7021 taataaccga taccgtcatc catccacaaa ccggccagac gatttccata ccgctggcta
     7081 atctctccca ctatcttttc cacatttgta aacaaatctc ctgcattatc acgtgtataa
     7141 tgctgcttgt cccaccattc tttatctcca tgaccgacat ggtaatacag aatcagacga
     7201 atgccgtatt tacccaacgc atcagataaa tcagccacta aatctctctt tgtggtacgc
     7261 cccggcaaaa tagaatcgat tgcctgtatc ggagccggga aataatattc cgcccacgac
     7321 gttgtaaaaa atatcaactt cccgccacat tcgtaaacag ttcgtgcaaa gcggtccaca
     7381 tcaaagttat tgaccgcatc ctcataggct aacggctctc ctgactgagg catactcttt
     7441 gaattccagt ggaagaaaaa gccataaggc aaatccgcca tccaggatgt attactgcga
     7501 agtgatgtag cttccgcccg cagctgctca taagtctccg gccgggtgac ttccaacgag
     7561 tacagataca cattaaaatc atcctgctta ccgggtttgc caatctttaa agataaaacg
     7621 gaagtcccct tattaaaatg taaaggacgg gggaaccggc aacgctgcca tccggttgta
     7681 tttatccggc aaataacact gtccgttcca ttggataata ccaactccgt ttcttcccca
     7741 tctcccatcc ggttgacaga aacgatcatt tcagccatgt agtcttcacc gtccgtattg
     7801 actttccagg atattgactg ctcgggagtt ttccagttct ccgcccagaa tgctttataa
     7861 ggttcttccg gataaagttg tttcacacca ttattcagtt ctccacgaaa aggaatcaac
     7921 cggtttatgt tcgccgaatc caggtttaat gccgtcggat caaccggatt actgcaagcg
     7981 gccagacaca taacaaacaa agacaaaaaa taaatatatt gctttttcat tcgtatttta
     8041 cggatatagg aagggccaat ccaataataa ctcagaccgg cccttcatat attctacatt
     8101 aattatctgt aatccggatt ctgaggtatg ttgttattca gaatttcggt atcaggaatc
     8161 aaccaagtat tgttgtaagc accgataggg acattcaatc tgctgccacg cgctttctgt
     8221 accttatcga atgtctgggt acgtttcaaa tcgtaccagg caaaaccctc ttcatacaat
     8281 tcatgctgac gttccagcag aacggcttca cggaactggt cctgagaaag tccgctcaag
     8341 tcaggcacgt ttgtcgggtc gttctggtcg acacgggcac gtttacggat agcattgata
     8401 tattgataag caccggccgg tccgtttatc tcattttcag cttcggcggc aatcagatac
     8461 atttcagcca aacgaatcaa ttgagtctgc caggtcaaaa tattggtatt agatgctggc
     8521 aactcctgtt ccagatactc ttcattgata tacttattat aatatgtacg cgcgatgact
     8581 ttatttcctt tcacatttac atactcaggt ttaattcccc attctttacg catgtcacct
     8641 ttatcgaagc tggcgataaa agcatctgtc ggaagataca aggctgtctg gctgccaatc
     8701 ggtgaagatt cattatgcat accgctatag ctatcgggag cggagaacaa ctgagcccag
     8761 atagtttcag ccgtataacg ttccgtctta aatactttat cgaaggtagg catcaaagaa
     8821 tactgaccgc tgttgattac ttcaagcgct ttctctttgg ctttcgcata attttctttc
     8881 tgattcatcg ggaaaccggc agaagtcaga tagatacgtg ccataatcgc ttttacgacc
     8941 catttattta cacgtcccat atcctgcgct tcttccggaa gtttttgttc cgcatccaga
     9001 atatcgtcaa aaataaactg atagatatca gcctgcggca tacggtctat tgccacgtcg
     9061 gcatcactgg tcacgacttt atcccgcaaa gggacatctc caaagaactg gaccaatgta
     9121 aaataagacc aggcacgcaa acatttcgcc tcaccgataa tacgattctt ggtttcggct
     9181 gtaaaatcct tatcttctat cgactccaat atcatatttg cattctttat cgtactgtat
     9241 ggtccggacc aggcatttct aaaggcataa aaaccatatc ccggattatt tgcccagata
     9301 tccccgacct gttcagccga ttcaggctta tcgttatagt cggcaaaaac ttccgtcaga
     9361 ttcagatttt gtccctgagg atataaccct ttcaaagctc cgtcaaaatc ttccaccgtt
     9421 tgatagaagg aagagggaga aataaatgtt ttcgggtctt cttccagcca atcggagcaa
     9481 gaagcagaca gaataaccgg tacagccagc aatatatttt taatcagtgt tttcattctt
     9541 ttcatacgta ttaaaattta acctgtaaac ccaaagtaaa tgatttcgca gacgggtaaa
     9601 cccctctgtc ccatccgttc acggcagaag acgtccagga tgcttccggg tcataatgag
     9661 aatagcttgt aatcgtaatc agattctgtc cgctcagata aaccgagata ttaggtttac
     9721 gggaacctgc gaaccattga gacggcaacg tataagccag tttgatatct ttgaatcgca
     9781 gatacgaacc gttttccacc caaaccgaac tcgggtcacc gaaggccaga taatccttgg
     9841 tcgcaacaga agcacgtgca tatttggcat tcggattttc aggagtccaa tggttttccc
     9901 agacatcttt gcggatattc catgtgccgc cgatattagt gatactttta ttaaattcat
     9961 taacgatatc accaccaaca ctacctatta acaggaatga taactcgaag ttattccaat
    10021 tgataatatt cgtcagaccg aaagtaaact taggctgcgt atttgcaata atcgttttat
    10081 cacctgttgt aataccagct ttcccgtccg tgtctttata ccggtaatca cctgctttct
    10141 tggttgcttc gccattcaaa cgagcttctt catccgtctg ataaatacct tctatttcgt
    10201 agccatacaa ttggaacgga gctttaccga caaacagagg gaaccagttt ccgccaccga
    10261 taggagcatc tatccgctga atcttatttc catacacatc cgaacccaaa tctttcacga
    10321 ttgatctatt ggatgtaata ttcaaattag tcgtccagtt cacttttcct ttcatattga
    10381 ttgtattgat agatatttca aaacctttat tatcaatacg tcctaagttt ctcaacatag
    10441 aagaatatcc ggaagacggg ggaagagtcg cattatacag caaatcacgc gtttgtttcc
    10501 aataatagtc aaaaccgata ttcaggcggt tggaaaagaa tccgaagtcg acacctatat
    10561 ccgtttgtgt agttgtttcc catttcaagt cgtcgtttgc catggaggac aaaccgaaac
    10621 caatatcttt tccatcaccg aaaataggac cggaagttcc cagacgggcg aaagtctgat
    10681 acgggctaat agattgatta ccggtctgtc cgatactggc acgcagtttc agattgctca
    10741 gccaatcaat atcttgcata aaattctctt ccgacaaacg ccaggccaat gcggcggaag
    10801 ggaagaaagc gaatttatgg ttcttactga atttagacga accgtcatat cgtgcggtga
    10861 cagtcaacag atatctttcc atcaggttat aattggcacg tcccaggaaa gaagccatcc
    10921 ggtaatcgct gtaaccggaa gacggagttc cgggtgtaga ggctactccc aaattattcg
    10981 tttcatagac atcgcgcaga aatcctgtac ctgagccgcc caaatcatta tactgatagg
    11041 tctggaaagt aacaccaccc atcaggttca atgcatgatt cttattgaac cgcttgtcgt
    11101 aggtcaaaat attctcatta ataatagtat aataattaga ttttgactta gatgcatcac
    11161 catccaattt acctccggca gacaaaccaa tcggaatgta ccgatcggaa ctacccgcat
    11221 tgacttcagc accggcattc acccggaaag tcaatccgtc gataatctca tagataagcg
    11281 acatattcgc cagtaagcgg gaattaacgg ttttattctt atacaattca gccataccga
    11341 cagggtttgt tcctccccag ggagttcccg agaaattggt gtacttgcca tcggcatctc
    11401 ttatttcctg tatcggagcc atgaccattg ccgtataagc aatcgctccc cagccatccg
    11461 cattactgtt cgctgtattc tgagttccgt atgaataagc aatactggca ttcaacgaca
    11521 aatttctcgc cagcttctgg tcgccattaa tacgcaatgc aaaacggtta taatcagaac
    11581 ctttgataat accttcctgg ttcatatagt tcagagagga gtacaacttc gttttatccg
    11641 taccgcccga gacagacacc tgatgactat gcgtcaaggc agtctgataa gccaggtcct
    11701 gccagtcatt gttcggcagc atagctgctt gctccggtgt gatggcaata ccgttcccgt
    11761 cattttggga aacttcattt accatggcga tataatcatc ttttcccagt aaatccagtt
    11821 tctttcttaa agaagaaaca ccgacatatc cattatattc aaggaccgta tcgccggtac
    11881 gtcctctttt cgtcgtaatc ataacgacac cgttcgcacc acgtgaaccg tagatagccg
    11941 tagaagatgc atctttcaat acttccatcg acagaatgtc ttccgggtta atatccgaat
    12001 tcatcttttc taccggcata ccgtcaatga cataaagcgg ttcgttacca cctgccaggg
    12061 agttacttcc acggacacga atcatcatcg attcacccgg ctgaccagtt ctggcattaa
    12121 cctgcacacc ggctatttgc ccctgcaacg cacggtcggc actggttata cccacctggc
    12181 tcacgtcctt catctgcacg gaaccgacag ctcccgtcaa gtcgctcttc tttaccgtac
    12241 cataaccgat aaccacaacc tcatccaagg cttcggaatc ctcgcgaagt gaaacattaa
    12301 cgacatctcc gcttccaacc tttacttcct gggtgttgta accaatataa gatatctgca
    12361 acacaccacc ttccgggact tccagactat accgtccgtt catatccgta actgtcccgt
    12421 tcgttgttcc ctttacgact acattcgcac caataacggg ttcaccggtt tcatccttca
    12481 caactcctga tatatttttc gttgaagaaa cagtacgggc ttgcttgttg ataataatat
    12541 gtccgttact gaacgttatc gaacaaccgg aaccttccag caactgttcc ataacctctt
    12601 tcacattact gttctttggt aactttgtca ggacgcgaga atcgtttact tcctgcgtgt
    12661 tataatcgac aaacagtttg gtctgttgct cgatttgttt gaaggctgtc ttcagtgtta
    12721 cattgcttcc ggtcaggcgc acttgttgat gttgcgcata agaaaataaa ctgatggaag
    12781 ataaagctgt aataaacaac agcctggata cactttttcc gttatttata cgtattagat
    12841 ctgtctctta tacacatc
//
