LOCUS       c00154_gnlPro..         5438 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKPBAAHO_154.
ACCESSION   c00154_gnlPro..
VERSION     c00154_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:14:00
            Original ID  :: gnl|Prokka|FKPBAAHO_154
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5438
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5438
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:5436]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..5436
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5438
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5438
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..1493
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_1"
                     /sec_met_domain="ILVD_EDD (E-value: 8.5e-185, bitscore:
                     603.5, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPM
                     EAGEWNGQHLDLIDAMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAI
                     GLALPGNGTIVATHENRTKLFEDAAKLIVENAMKYYEVGDESLLPRSIATRQAFLNAMT
                     LDIAMGGSTNTVLHLLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRA
                     GGIIAILAELAKGGLIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFN
                     LVLGSQGAYYQELDKDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIW
                     KFTGPAKVFDSQEAACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLG
                     KECALITDGRFSGGTSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEE
                     LAARPMTPVTRDRYVPKSLKAYASMVSSADKGAVRLID"
     CDS             1541..3238
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-47, bitscore:
                     148.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRIFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTRERSIVTSGGLGTMGFGLPAAIGATFGRPDRIVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGAFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             3257..3820
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.7e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             3820..4563
                     /locus_tag="ctg154_4"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEV
                     SENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             4627..5436
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg154_5"
                     /sec_met_domain="IlvN (E-value: 8.3e-48, bitscore: 150.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.3e-25, bitscore: 76.2,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGTVENVVIRDEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     ALNLRDNGFNVIVGQRQGKTYDKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPPADIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGNAMDRTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCST"
ORIGIN
        1 gcgtagaata tatggtcaat gcgcacaagg cggatgcaat ggtatgtatc agcaactgcg
       61 ataagattac cccagggatg ctgatggctg ccatgcgcct gaatatccct accgtatttg
      121 tatccggcgg accgatggaa gccggagagt ggaacggtca gcatctggac ttgatcgatg
      181 ccatgattaa atcggcggac gacagtgtaa gcgatcagga agtagcgaat atcgaacaga
      241 atgcctgtcc tacctgtgga tgttgttccg gaatgtttac ggcaaactcg atgaactgtc
      301 tgaatgaagc tatcggcttg gctcttccgg gaaacggcac aatcgtggct acgcacgaaa
      361 atcgtacgaa actgtttgaa gatgctgcca aactgattgt ggaaaatgca atgaaatatt
      421 atgaagtagg tgacgaaagt ctacttcccc gcagcatagc tacccgtcag gcattcctca
      481 atgccatgac gctggatatt gcgatgggcg gttctaccaa tacggtgctt cacctgttgg
      541 ccgtggcaca tgaggcagga gtcgatttca agatggacga catcgatatg ctgtcacgca
      601 agacaccctg cctgtgtaaa gtcgctccga atactcaaaa atatcatatt caggacgtta
      661 accgtgcggg tggcatcatt gctatcctgg cagagttggc aaaaggcggt ctgattgata
      721 cttccgttct ccgtgtggat ggcatgtcgc tggcggaagc gatcgatcaa tattcaatta
      781 ccagcccgaa cgttacggaa aaagcaatga gcaaatattc aagtgcggca ggaaacagat
      841 tcaatctcgt acttggttct cagggagctt attatcagga attagataaa gatcgcgcga
      901 acggatgtat ccgtgatctg gagcacgcct atagcaagga cggaggcctg gcggtactga
      961 aaggaaatat cgctcaggat ggttgcgtag taaaaacggc gggtgtagac gaaagcatct
     1021 ggaagtttac cggacctgcc aaagtattcg actcacaaga agcagcctgt gaaggcatcc
     1081 tcggaggccg agtcgtcagc ggcgacgttg tcgtcatcac gcacgaaggt ccgaagggcg
     1141 gtcccggtat gcaggaaatg ctttacccga cttcttatat caaatcccgt cacctcggca
     1201 aagaatgtgc cttgattacc gatggacgtt tcagtggtgg aacttccgga ttgagtatcg
     1261 gacacgtttc tcccgaagcc gccgccggag gtaatatagg aaaaatagta gatggagata
     1321 tcatcgaaat cgacattccc gcccgaacga ttaacgtgcg actaacagat gaagaactgg
     1381 ctgcccgccc gatgactccc gtgacccgtg accgttacgt gccgaagagc ctgaaagcat
     1441 acgccagcat ggtaagctct gccgataagg gagcagtgag attaatagac tgatccactt
     1501 cattatccat tatgaatcat ccattatcca ttaaagaact atgagtaagg acttaataac
     1561 aggcgcagag gcaatgatgc gctctctgga acatcaggga gtgactacca ttttcggtta
     1621 tcccggcggg tccatcatgc ctacgttcga tgccctgtac gaccatcaaa atacattgaa
     1681 ccatatcttg gttcgccatg aacagggagc tgcccatgcg gcacaaggct acgcccgtgt
     1741 atcgggtaaa gtcggtgttt gcttggtgac aagcggcccc ggagcaacca atacgatcac
     1801 aggtattgca gatgcaatga tagacagtac gcctatcgtt gtcattgcag gacaggtggg
     1861 aacaggcttt cttggaacag acgcttttca ggaagtcgat ctcgtaggta tcactcagcc
     1921 aatcgctaaa tggagctatc agattcgccg tgccgaagac gtagcctggg cgatagcacg
     1981 tgctttctac attgccagta gtggtcgtcc cggtccggtg gtactcgact ttgccaagaa
     2041 tgcgcaggtt gaaaaaacga aatacgagcc gacaaagcag gagtttatcc gcagctatgt
     2101 tccggttccc gatacagacg aagaatcggt aaaggctgcc gccgaactga tcaataacgc
     2161 cgaacgcccg cttgtcttgg taggacaggg agtggaactg ggaagcgctc aggaagaact
     2221 gcgtatcttt atcgaaaagg cggatatgcc cgcaggttgt accttgctcg gactttccgc
     2281 attgcctacc gatcatccgt tgaataaagg aatgctgggt atgcacggaa atctgggacc
     2341 gaatatcaat actaacaaat gtgatgtact gattgctgtc ggtatgcgtt tcgacgaccg
     2401 tgtgaccggt aatctggcta cttacgccaa acaagcgaaa gtgatccatt ttgacattga
     2461 tccggcggaa gtaaataaga atgtaaaggt agatattgcc gttttgggcg actgcaaaaa
     2521 gacgctggct gctgtgaccg gactgttgaa aaagaaccgg cacaccgagt gggtcgatag
     2581 tttcaaggaa tatgaagcgg tagaggaaga aaaagtcatt cgtcctgaac ttcatcctgc
     2641 aacggattca ctgagtatgg gcgaagtggt gcgtgcggta agcgaagcga cccgtcacga
     2701 agccatattg gtgacagatg taggtcagaa tcagatgatc tctgcccgct actttaaata
     2761 taccagggaa cgtagtatcg ttacttcggg tggactcggc acgatgggtt ttggccttcc
     2821 ggcagctatc ggagctactt tcggccgtcc tgaccgcatt gtatgtgtat ttatgggtga
     2881 cggcggactg caaatgaaca ttcaggaact gggtacgatc atggaacaga aagctccggt
     2941 gaagattatc tgcctgaaca acaattatct cggcaacgtg cgccaatggc aggctatgtt
     3001 ctttaatcgc cgttattcat ttactccgat gctgaatccg gattacatga aaatcgcttc
     3061 cgcctacgat attccttcca aacgtgtctt ttcacgggaa gaattgaaag cggccatcga
     3121 cgaaatgctc tcgacagacg gggcgttcct gctcgaagcc tgtgtggtag aagaaggcaa
     3181 tgtcctcccg atgacccctc cgggcggttc agtcaatcag atgttgctgg aatgttaatc
     3241 cttaatttag aaagttatga gtgataagac attatatacg attatagttc attctgaaaa
     3301 tatagccgga ttgctgaatc aggtgaccgc tgtatttacc cgtcggcaaa taaacatcga
     3361 gagtttgaac gtttctgctt cttccattaa aggagtacat aaatatacga tcacagcgtg
     3421 gactgataag gacactattg aaaaggtggt gaagcagatc gaaaagaaga ttgatgtgat
     3481 tcaggcgcac tattttactg aagacgagat ttatttccat gagatagcct tatataaggt
     3541 atctactcct gcttttcagg agactccgga agcatctaaa gtgatccgca gatataatgc
     3601 ccgcattgta gaggtgaatc cggtattctc tatcgtcgag aagaacggca tgagtgaaga
     3661 gattacttcc ctttacgaag aacttcgggc tttgaaatgt gtgctgcaat ttgtccgttc
     3721 gggtcgtgtg gctattacta ccagctgttt cgaacgtgtg aatgagttcc tggacggaca
     3781 ggaagcgaag tataagcaaa gtaaaaagga acaggagtaa tgagtgaaga aaataaaata
     3841 gggacttatc agtttgtggc agagccgttt cacgtagatt ttaacggccg cctgaccatg
     3901 ggcgtgctgg gaaatcatct gttgaattgc gcaggttttc atgccagcga ccgtggattt
     3961 ggtattgcta cgctgaacga ggacaattac acatgggtgc tttcccgcct ggctatcgag
     4021 ctggatgaga tgccttacca gtacgagaag ttctcggttc agacatgggt ggagaatgtc
     4081 tatcgtctct ttaccgaccg taactttgcc gtcattgaca aggatggaaa gaagatcggc
     4141 tatgcccgtt ccgtatgggc gatgatcaat ctgaataccc gtaagcctgc cgatctgttg
     4201 gcattgcatg gaggaagcat cgtcgattat atatgcgatg aaccctgccc gatagaaaag
     4261 ccttcgcgta tcaaggtgac aagcaatcag cctgttgcga cgctgacggc aaaatacagt
     4321 gatatcgata ttaacggaca cgtaaacagt attcgttata tcgagcacat acttgacttg
     4381 tttccgatag aactgtatca gacgaaacgt atccgccggt ttgaaatggc gtatgtggct
     4441 gaaagttatt tcggagatga actctctttc ttctgtgatg aggtgagtga aaacgagttt
     4501 catgtagagg tgaagaaaaa cggcagcgag gtagtatgcc gttccaaagt gatatttgaa
     4561 taatatagag tataaaatca attaataaca gatggcgcaa gtcatcaaaa caaaaaaaca
     4621 aaaaaaatgg cacagttgaa ttttggcgga actgtagaaa atgtagttat ccgtgatgaa
     4681 tttccattgg aaaaagctcg tgaagtattg aaaaatgaaa caatcgctgt aatcggttat
     4741 ggcgtacaag gtcccggaca ggctctgaac cttcgtgata acggtttcaa tgtaatcgtt
     4801 ggtcaacgcc agggaaagac atatgacaaa gcggttgctg acggatgggt tccgggtgaa
     4861 actttgttcg gtattgaaga agcttgcgaa aaaggtacga tcattatgtg cctgttgtct
     4921 gatgcagcag taatgtctgt atggcctact atcaagcctt acctgactgc aggaaaagct
     4981 ctttatttct ctcatggttt tgctattaca tggagtgacc gcacaggtgt agttcctcct
     5041 gcagatatcg acgtaatcat ggttgctcct aaaggttcgg gtacatcctt gcgtactatg
     5101 ttccttgaag gtcgcgggtt gaactcttca tacgctatct atcaggatgc aacaggcaac
     5161 gctatggaca gaacaatcgc attgggtatc ggtatcggtt caggttattt gttcgaaaca
     5221 actttcatcc gcgaagctac ttccgacctg acaggcgaac gtggttcatt gatgggagct
     5281 atccagggtc tgttgctggc acaatacgaa gtgttgcgtg aaaacggtca cactccttcc
     5341 gaagcattca acgaaactgt agaagagctg actcagtcat tgatgccgtt gtttgcaaag
     5401 aacggtatgg actggatgta tgctaactgc tctactac
//
