LOCUS       gnlProkkaOBMANACO_82   13210 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBMANACO_82.
ACCESSION   gnlProkkaOBMANACO_82
VERSION     gnlProkkaOBMANACO_82
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 19:16:37
            Original ID  :: gnl|Prokka|OBMANACO_82
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13210
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13210
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[9862:12292]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9863..12292
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..13210
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13210
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             260..1429
                     /gene_functions="other (smcogs) SMCOG1054:hypothetical
                     protein (Score: 219.1; E-value: 2.2e-66)"
                     /gene_kind="other"
                     /locus_tag="ctg82_1"
                     /transl_table=11
                     /translation="MAVKILSVDDELDLEVLLTQYFRRQIRKGEYEFAFAHNGLEALQK
                     LLETPDFDIILSDINMPEMDGLTLLAKVNELKNPAMKCIMVSAYGDMDNIRSAMNKGAF
                     DFATKPIDLDDLSRTIEKAIEQVRYIRESQQEHNQLESIKNDLAIAGEIQQTILPRSFP
                     PFPELTEVVDIYASMTPAKDVGGDFYDFFQIDDERIGLVIADVSGKGVPASLFMAVSRT
                     LLRATALRGVSSAECLTYANKLLCKESLDSMFVTVFYGIYHYKTGMMDYTNAGHNPPYL
                     LRGGRTVECLPVASNFVVGVFDDIEFESNTLTFGIGDTLLLYTDGVTEAFNDKREQFSE
                     SNLQDILASMHESSSAKEVVTSVLQSVKTFSGDYPQSDDITLLSLQRIK"
     CDS             1448..1753
                     /locus_tag="ctg82_2"
                     /transl_table=11
                     /translation="MEKYEIHFVGSVLDSNTSGDEQAKIVALIEQGHSVALNLSGCSYV
                     SSAGLRVMLYAFKLAKAKSRDVCLVGVSQEVKDVMHMTGFDKFFRFYQTLDELSQP"
     CDS             1768..2196
                     /locus_tag="ctg82_3"
                     /transl_table=11
                     /translation="MTLLQFRPVDGRLDEILSMLMHSREVASHPSLSYAIRLVSEEIIV
                     NILNYAYPQQAEGYLTLCLWDEDGEITLEFIDGGIPFNPLDKADPDISLPLEQREIGGL
                     GIFLVREMMDDVAYTYVNKENRLTIKKKYLQPTDEPVS"
     CDS             2193..3794
                     /locus_tag="ctg82_4"
                     /transl_table=11
                     /translation="MIKLNENIIRWIIAVPCILLTVCLVLYRAYRHSASDRERLALSLE
                     EFRDKEKKSVLIQRVSQQMEEIAYQQKDISEKRRQEAVAQTQKANRMQQQAELARERAL
                     AAQLEAEKAYRMADEQKNLAMERQLQAEQSKRVADTLAFLALGRSLGTLSVTQYRSGNM
                     ELASLLAYTAWWFTKRYDGDVYHPAVFNALSLSCRQDQLWFGHKGAVTGIKLLSGGEEK
                     ARAGRNPLPGLVTVGKYGEMIRWKSENGQTYTSELLLNDPCYDFRDVLLRSDSQMYALS
                     YCGQLISTDSAGIVTRFLPKGEYRQLISIASNLVLAVSTTGIYSFDCVNHEIQPYFQPE
                     HSITCVGQMEGYLYVFFKNGTVALLSSDGTFLRFIDSLPENSVVTAFCPLTNERYAIGC
                     REGVILICDKNGNIRQKLIGHQAAVTAISRKGNKLFSSSYDCTLRLWDLRKGKTESAVI
                     VTSPGWIHTFCFHPDGTSVFIGDEQGRLYRVPVSPDHMATVVRQGLQRDFTREEWEYYI
                     GKQIPFESYYLKTYQP"
     CDS             3791..6628
                     /locus_tag="ctg82_5"
                     /transl_table=11
                     /translation="MKKIVFLIMCLCSVYANSQEGIPFFVNYPASVYQAHNRNFDVVCD
                     SCGNVYFANFEGILHYDYNRWETIYTPGFSRVTRLFRDSEGRIWVGGYNVFGRIERDGR
                     GCITLRTLLSDLDTDSLGELEDMAEIDKRIYLKATSGRYYTVQSDSILTPVQVLPAQLQ
                     EKWRNQSSVSMNRAFSLPGGETISINSAHGLIMDDSGKKERFSVTERNGLCSNAVSGIA
                     ADGRGNLWGATDNGVFHVFIPSLFSRYTSGEGLKGEVISAVSYKGMIYIGTLQGLYVLK
                     QNTFVPVQGISQACWQLCLSPQGELYAASGDGVYVIRDYNHSEKLTDMAAYSLAFIGHT
                     NLLMGTMDGIYQYSADEERIKKISDVEKVVRLEVKKDRSVWAKTLYGEIYLREEGESSF
                     VLQDRESEEVMTEYTDNDGCHWQTNLKGKEVQVHHSQIDTEKFNQCLYAIRNYVVRVIY
                     IEEDRAAWFGGDFGLIRMDLEKARTFTPVAPCIYLREVCLNRDSVYWGGDLPEESGGAD
                     WQINSTVPRLGNDVRSIRFSFATDAPCFTGSNEYRYRLVGYDPEWSSWDSGTVKEYANL
                     SSGTYTFCVRARDIYGTESEMKQFRFSLLPPFYLQWYCLILYTVAFGMLLFLLFKWRMR
                     SLLKEKERLEALVGQRTKQLVQQKNEIEEKSLKLEKALKELGQAQDELVRQEKMATVGK
                     LTQGLIDRILNPLNYINNFSHLTSGLLKDLYQNLESVKELLDEDTYLDSVDVINMMRDN
                     LEKIEEHGSNTTRVLKAMEEILRDRNRQLEKTELIGLCRKDMELLSSYYQKEITAMHIA
                     VRTSLPDNPLFIDGNAEQLGKTIMSLLNNGMYAIAKKYGKKAYPAEIGLALESKDGQAV
                     IRLYDNGVGIEQSILDKIFDPFFTTKTTGEAAGIGLYLSKEIILNHHGQIAVRSEKDEL
                     TEFTITLPLWEEKSV"
     CDS             6651..7487
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 136.3; E-value: 3e-41)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg82_6"
                     /transl_table=11
                     /translation="MGKNISQEKRIEELEARLKEQEKLGSLGLLSAGIAHEIQNPLNFV
                     INFSKLSGQLLADLADRVDEAKARIPEAELEDIKDILSGLRENVDKIKEHGDRAISIIR
                     GILLYSRGKEDEFMPTQIQKLTKEYVWLAYHAMRANYKNFNIAIREDYAKDIPSIRLIP
                     QDFSRAVLNVMNNACYAVWKKWQNAPEGYSPEIMVTLEKLDKRIVLSIRDNGEGMGPEV
                     KRKLFDSFFTTKPVGQGTGLGMAIVRDIIENKHHGKVLFDSVLHEYTCFRFIIPIA"
     CDS             7484..9850
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 170.2; E-value: 1.7e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg82_7"
                     /transl_table=11
                     /translation="MKRCLLYILCCFGVVQLSAQPADNIRNSFVKAETFYKSGDIDEAC
                     RILEENLSSFQGTMHTEACRLAALCCLALDRFPEAEKYVSLLLKDEPYYYISLQDPERF
                     ADMVRKHRETKVTLVTASQQVETPEEAPVPVTLITEEMIRAIHARCLRDVLIAYVPGIS
                     GLSSNEEMNLAMRGVYSPEQENILIMQDGQRLNSYITNAVSPDYGISLAKVKQIEVLRG
                     PASSLYGSVALTAVINIVTKDGVDVRNGSISVSAGNRGQLAADLLLGKHDMNMDFMAWF
                     SLYRATGESVFVPAEKQYALYPRDGFIRLDNYSGFPAMDGGIKLQRGNLLFSFSMNYAK
                     KRQPYSMWLFSSPYSYERFRTFDGSGPGYSRWSAREQAVYSRTWQRITFSTAFYTDWNK
                     NVHYETSGDTLQDYPIFPNYDYQPIIYPTRGAFQYIRWMDFNVGFNGRVNYAYDWGKLG
                     KGNMLGGVEWNRYTLYDSEYLEGMNFKEIVRTWIEKRLYTGHEMNTDAFLQIKHNLHQN
                     WIVNAGIRYDYKRRSNKRTLQAFSPRLSLIYLRNGLNIKASYSRAFVDAPYYYRNNEMD
                     TYSGGENLQAEYLSSYQVTCAYHHSPSHIDVECNLFYNRASHFLFTQPETRVYENAGSL
                     DMGGVEVVARYKADRLSLDGNLCFQKVLDYTNFFVTDGSVNNVPGFSMNLVANYFLLKK
                     KVQSWSAHLKLNCSSHCYTQVSVLEDGLNGDATNYTVRLPGYAVFSFTTRYKYKRVEGS
                     LGIENLFNNRYECGGATVPIRQKGRWISASILYNF"
     CDS             9863..12292
                     /NRPS_PKS="Domain: AMP-binding (16-401). E-value: 1.2e-82.
                     Score: 269.6. Matches aSDomain:
                     nrpspksdomains_ctg82_8_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (509-568). E-value: 2.7e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg82_8_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     255.5; E-value: 1.4e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg82_8"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-88, bitscore:
                     284.2, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 4.3e-11, bitscore:
                     32.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNIQENLSRSLFIWGDKPAVVAKDGTVSYQMLERYSANIAQSI
                     RQRLSVTDPSGLRNICIGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAEN
                     ADMVLLLTDSSNEVGGIPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNP
                     KGVRISYRNLDTFTRNLVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLIL
                     AGEDERRDISLLDELIRREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNR
                     LKQQPYRLMNVYGPTENTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGAT
                     GELCLGGPQVSLGYIGSVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVK
                     IRGFRIELTEIAERLNRDPDVERAHVVVVERNGRQLLGAYLQPSVSGNFHPEEVKERLR
                     AELPYYMIPNLWQVVDHFQRTINDKIDVRALPAFTSLELKYVPPVHPGEVILCGILKEM
                     LGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPINVSAVYTARNLRRLLLVPRQEP
                     IYWYRQQNLKKPVIILVCGSAYFNHLYFNLADRLYPKYDFLVVDAIYDHFNKVATDIPE
                     LLEYYVRTVQPMIRERTVYALTGFCMGAELAVGLAEMLHRFMGIMPKVFALDGQAWQNP
                     ALWQNYPLLVFPGDTDEMVRERNEIINIYFRTTPNLIYQGEVIVLLSGLFHQQAGLSPE
                     ESWTEESYRIFRTEYDNCERLWNKYYPNAPVLRLPTDHWHFLEGESLEQLITVFLK"
     aSDomain        9911..11065
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg82_8_AMP-binding.1"
                     /evalue="1.20E-82"
                     /label="ctg82_8_AMP-binding.1"
                     /locus_tag="ctg82_8"
                     /protein_end="401"
                     /protein_start="16"
                     /score="269.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="GDKPAVVAKDGTVSYQMLERYSANIAQSIRQRLSVTDPSGLRNIC
                     IGVCMERNKTLVPAILAIFRLGATYLPIDPSLPDNRKRYMAENADMVLLLTDSSNEVGG
                     IPSVRQLYLNGEQLSEPVVGDYTEVLPNDCAYIIYTSGTTGNPKGVRISYRNLDTFTRN
                     LVDKKLYHLSDPANRYLAFASISFDASILELMMCIPVGGTLILAGEDERRDISLLDELI
                     RREKVNIAFFPPSLLGMFADLDFPSFKTLLFGAEAIGEKLFNRLKQQPYRLMNVYGPTE
                     NTVLSTIRIVGKDTSYDDIGYPLKGTVCYVLSENLQQTTLGATGELCLGGPQVSLGYIG
                     SVQLNEKSFISYDGERLYRTGDLVQQQPDGSIRFIGRKDTQVKIR"
     aSModule        9911..11566
                     /complete
                     /domains="nrpspksdomains_ctg82_8_AMP-binding.1"
                     /domains="nrpspksdomains_ctg82_8_PP-binding.1"
                     /locus_tags="ctg82_8"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       10091..10132
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg82_8_0001"
                     /evalue="3.50E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg82_8"
                     /protein_end="90"
                     /protein_start="76"
                     /score="11.0"
                     /tool="antismash"
                     /translation="LAIFRLGATYLPID"
     CDS_motif       10313..10369
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg82_8_0002"
                     /evalue="1.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg82_8"
                     /protein_end="169"
                     /protein_start="150"
                     /score="26.8"
                     /tool="antismash"
                     /translation="AYIIYTSGTTGNPKGVRIS"
     CDS_motif       10871..10957
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg82_8_0003"
                     /evalue="1.20E-08"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg82_8"
                     /protein_end="365"
                     /protein_start="336"
                     /score="27.3"
                     /tool="antismash"
                     /translation="LGATGELCLGGPQVSLGYIGSVQLNEKSF"
     CDS_motif       11030..11092
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg82_8_0004"
                     /evalue="1.50E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg82_8"
                     /protein_end="410"
                     /protein_start="389"
                     /score="36.2"
                     /tool="antismash"
                     /translation="FIGRKDTQVKIRGFRIELTEI"
     aSDomain        11390..11566
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg82_8_PP-binding.1"
                     /evalue="2.70E-10"
                     /label="ctg82_8_PP-binding.1"
                     /locus_tag="ctg82_8"
                     /protein_end="568"
                     /protein_start="509"
                     /score="32.6"
                     /tool="antismash"
                     /translation="LCGILKEMLGLPQVSVEADLIDDLGLTSLDMLRLVTEANKKGCPI
                     NVSAVYTARNLRRL"
     CDS             12297..13187
                     /locus_tag="ctg82_9"
                     /transl_table=11
                     /translation="MQTENFTLGKKELLILLGLTLVLPFPINWALIELNPLTLMAGADD
                     VPTWIGFGGSYIGGIIGGIISIMILNKTLQQTGVLHHDLKLLQLDTIIYTQQQDWFTGF
                     KQELAENLKSIDLYVLNTVVSSISMKNYAYAKEVLTEINKGLEYQMVAASFSFTSTHLS
                     SEEKKYMNLVRRVQTEYSSFIKDILYYIPLAETISSRKKLNYDQLMDYTLSQYDYLQGQ
                     EGESTASGAIIPRVMEIDPSDDIRKELERIMEERLTGRTYLYHLKSDLAEATHQLIIYE
                     ENRINSILHLSLIHI"
ORIGIN
        1 tacacgcgta agatcgtcgg cagcgtcaga tgtgtataag agacaggaat agtttctttc
       61 aggagtgtaa atcaatcttt caggtgctgt cttctaaggc acgaaagcaa tataactgta
      121 tgcttataag acaatatcat ccattcggaa aaacattttt cctgtttaaa atataaaatt
      181 gtaaccgggg cggtcacgct ctatttttgc catcataaac gtcagaacaa acggttgaaa
      241 ttcataaata acaatagata tggcagtaaa aatattgagt gtagatgatg aactcgattt
      301 agaagtatta cttacccagt acttcaggcg acaaatacga aaaggtgaat acgagttcgc
      361 ttttgcccat aacgggttgg aagctttaca gaaacttctg gaaactcccg atttcgatat
      421 catcctgagt gatattaata tgccggagat ggatgggttg accctattgg ctaaggtcaa
      481 tgaactgaaa aatccggcaa tgaagtgtat aatggtctct gcttatggag acatggataa
      541 catacgttct gctatgaaca agggagcgtt tgattttgca accaaaccga tcgatttgga
      601 tgatctgtcg cggactattg aaaaggcgat cgaacaggtt cgctatatcc gtgagtcaca
      661 gcaggagcac aaccaactgg aatctatcaa aaatgacctg gccattgcgg gagaaatcca
      721 gcaaacgatt cttccccgtt cctttcctcc ttttccggaa ctgacggaag tggttgatat
      781 ttatgcttcc atgactccgg caaaagatgt aggtggcgat ttttatgatt tcttccagat
      841 tgacgatgaa cgtatcgggc tggtgattgc tgacgtatcc gggaaagggg tgccggcatc
      901 cttgttcatg gcggttagtc ggaccctgct ccgtgcaact gctcttcggg gtgtttcgtc
      961 ggcagaatgc cttacttatg ccaataagtt actgtgtaaa gagagcctgg actctatgtt
     1021 tgttacggtc ttttatggga tttatcatta taaaaccggc atgatggact ataccaatgc
     1081 cgggcataat cccccttatc tccttcgcgg cggacggact gttgaatgct tgcctgtcgc
     1141 ttctaatttt gtggtaggcg tattcgatga tattgaattt gagagtaata cattgacgtt
     1201 cggcatcggt gacactttac ttctgtatac ggatggtgtc acagaggctt ttaacgacaa
     1261 gcgggaacaa ttctcggaaa gtaacttaca ggatatattg gcgtctatgc acgaaagtag
     1321 ttccgcaaaa gaggttgtta cgagtgtatt gcagtctgtt aagactttct ccggagacta
     1381 tcctcagtcc gatgacataa ccctgctttc tcttcaacga atcaaataat attaaaataa
     1441 aagaacgatg gaaaagtatg aaattcattt tgtaggttcc gtcttggatt caaatacaag
     1501 cggtgacgaa caagcaaaaa ttgtagctct tatcgagcaa ggacattctg ttgcattaaa
     1561 tctcagcggc tgttcttatg tatccagtgc cggattgaga gtcatgcttt atgcctttaa
     1621 gctggcgaaa gctaaaagta gagatgtttg ccttgtcggt gtgtcacaag aggttaaaga
     1681 cgtgatgcac atgaccggat tcgataaatt ctttcgtttt tatcagactc tcgatgaatt
     1741 atcacaaccc taaaaattac ctgagcaatg acgttacttc agtttcgccc tgtcgatggg
     1801 aggttagatg aaattcttag tatgctgatg catagtcgtg aagttgcttc acatccttcc
     1861 ctgtcttatg ccatccgttt ggtcagtgaa gagatcattg tcaatattct caattacgct
     1921 tatccgcagc aggcagaagg ttatctgact ctgtgcttat gggatgaaga cggagagatt
     1981 actttggagt ttatagatgg tggtattcca ttcaatcctt tggataaagc cgatcctgat
     2041 atttcattac cgttagaaca acgtgaaata ggaggattgg gcattttctt ggtacgtgaa
     2101 atgatggatg acgtagcgta tacgtacgtg aataaggaga atcggttgac cattaaaaag
     2161 aaatatctgc aacccactga tgaacctgta tcatgatcaa gttaaacgaa aatataatcc
     2221 gttggatcat tgccgttcct tgtatacttt tgacagtatg tctggtccta taccgggcat
     2281 atcgtcattc ggcatcggac agggagcgtc ttgctctgtc tctggaggaa ttccgggata
     2341 aagaaaagaa atcggttctt atacaacggg tcagtcaaca aatggaggag attgcttatc
     2401 aacaaaagga tatttccgaa aagagaagac aagaagccgt tgcgcaaact caaaaggcca
     2461 accgaatgca acagcaggca gagttggcac gggaaagagc gcttgctgca caattggagg
     2521 ctgagaaagc gtatcggatg gcagatgaac aaaagaatct ggcgatggaa cggcaactac
     2581 aggccgaaca gtcgaagagg gttgccgata cattggcttt tctggctttg ggacgttcat
     2641 tggggacact ttctgttact caatatcggt cgggcaacat ggaattagct tctctgttgg
     2701 catataccgc ctggtggttt accaagcgat atgatggcga tgtatatcat ccggctgttt
     2761 tcaatgcatt gtctttgtct tgcaggcaag atcagctttg gttcgggcat aaaggagctg
     2821 ttaccgggat caaactgtta tccggaggcg aggaaaaagc aagagccggt cggaatcctc
     2881 tgccgggatt ggtcactgtc ggcaagtacg gtgagatgat acgttggaaa tcggaaaatg
     2941 ggcagaccta tacctccgaa ttactgttga atgatccctg ttatgatttt cgggatgtgc
     3001 tgttgcggtc cgattcacag atgtatgcct tgtcatactg cgggcagctt atctccacgg
     3061 attccgccgg tatcgttacc cgctttttgc ctaaaggaga atatcggcaa ttgatttcga
     3121 ttgcctctaa cttggtattg gcggtttcca caacaggtat ttattctttt gactgtgtca
     3181 accatgagat acaaccttat tttcagccgg aacattcgat aacttgtgtc ggtcaaatgg
     3241 aaggctatct ctatgttttt tttaagaatg ggacagtagc tttactttcg tcggatggta
     3301 catttctcag atttatagac agcttgcccg agaatagtgt ggttactgca ttctgtcctc
     3361 ttaccaatga aagatatgcc attggctgtc gtgaaggagt catcctgatt tgtgataaga
     3421 atggaaatat ccggcagaag ttgatagggc atcaggctgc ggttactgct atttcccgga
     3481 aagggaacaa actgttttcg agtagttacg attgtacgct gcgtctgtgg gatcttcgta
     3541 aaggaaagac cgagtcggcc gttattgtga caagccccgg ttggatccat actttttgct
     3601 ttcatccgga cggtacatct gtctttatag gagacgaaca ggggcggttg tatcgggtgc
     3661 ctgtttcacc cgatcacatg gctactgttg tccgtcaggg gttacagcgt gattttactc
     3721 gagaagaatg ggagtattat atcggtaagc aaattccatt tgaatcctat tacctaaaaa
     3781 cgtatcagcc atgaaaaaga tagtcttttt gataatgtgt ctttgctcgg tatatgcaaa
     3841 ttcacaagaa ggtatcccat tttttgtaaa ctatccggct tcggtttatc aggcgcacaa
     3901 tcgtaatttc gatgtcgttt gcgacagttg tggaaatgtc tattttgcta atttcgaagg
     3961 tatccttcat tatgactata accgttggga aactatttat acaccgggtt tttcccgtgt
     4021 cacccgtttg tttcgtgatt cggaaggtag gatatgggtg ggaggatata acgtgttcgg
     4081 acggatagag cgtgatggac gcggatgtat tacgttgaga acccttcttt ccgatctgga
     4141 cacagactct ttgggcgaat tggaagatat ggcagaaata gataaacgca tttatctgaa
     4201 agctacatca ggaagatatt atacggttca gtcagattcc attttgacac cggttcaggt
     4261 acttccggcc caattgcagg aaaagtggag aaatcaatcc tcagtctcaa tgaatcgggc
     4321 gttttctcta cccggaggag aaacaatctc gataaactct gcccatggat taataatgga
     4381 tgacagtggg aaaaaagaac ggttttccgt aactgagaga aatggcttat gcagtaacgc
     4441 tgtttcgggt attgcggccg atgggcgtgg caatctctgg ggagctacgg ataacggtgt
     4501 gtttcatgtt tttattccct ctttgttcag ccgttatacc tctggtgaag gtctgaaggg
     4561 agaggtaata tcggctgtct cttacaaagg aatgatatat atcgggacct tacagggatt
     4621 atacgtattg aagcaaaaca cttttgttcc tgttcaggga atttcgcaag catgttggca
     4681 actgtgtctt tctccacaag gagaattata tgcagcgtcc ggcgatggtg tgtatgtgat
     4741 ccgggattat aatcattcgg aaaaactcac agatatggca gcttattcat tggcattcat
     4801 tgggcatacg aaccttctga tgggcactat ggatgggatt tatcaatatt cggcagatga
     4861 ggaacggata aagaaaattt ccgatgtcga aaaagtcgtt cgtctggaag tgaagaaaga
     4921 tcgttctgta tgggctaaaa cgttgtacgg agaaatctat ttgcgggaag agggcgaaag
     4981 ctcttttgta cttcaagaca gagagagtga agaagtaatg accgagtata cggacaacga
     5041 tggctgtcat tggcagacaa atctgaaagg aaaagaggta caggtacatc attcgcaaat
     5101 tgatacggag aaattcaacc aatgcctgta tgccattcgg aattatgtcg tgagggtgat
     5161 ttatattgaa gaagacaggg cggcatggtt cggcggtgat tttggtttaa ttcggatgga
     5221 ccttgaaaag gcccggacat ttactccggt tgctccctgc atctatcttc gtgaagtttg
     5281 tctgaaccgt gattctgtct attggggagg agatctgccg gaagagtccg ggggagcgga
     5341 ctggcagata aatagtacag tacctcgttt ggggaatgat gtacgttcca ttcgtttttc
     5401 atttgctacc gatgcgccct gtttcaccgg ttccaatgag tatagatatc gcctggtcgg
     5461 ttatgatccg gaatggagtt cgtgggattc cgggactgtg aaagagtatg ccaacctttc
     5521 gtcgggtacg tatacgtttt gtgtccgggc ccgtgatatt tacggcacag agagtgaaat
     5581 gaaacaattc cgcttttcgt tattgcctcc tttttatttg caatggtatt gtctgatcct
     5641 atataccgtt gcttttggaa tgctgttgtt cttattgttt aaatggagaa tgcgcagttt
     5701 gctgaaagag aaggagaggt tagaggccct tgtcggccaa cgtaccaaac agttggtaca
     5761 acaaaaaaat gaaattgagg aaaagtcctt aaaattggaa aaagcattga aggagctggg
     5821 ccaggcacaa gatgaattgg ttcgacaaga aaaaatggct actgtaggta aactgactca
     5881 agggttgatt gaccgtattc tgaatccgtt gaattacatt aataattttt cccacttgac
     5941 ctcaggatta ctgaaggacc tatatcagaa tctggagagt gtaaaagaac ttttggatga
     6001 agatacctac ttggattcgg tagatgtcat caacatgatg agagataatc tggaaaagat
     6061 tgaggaacat ggaagtaaca ccactcgtgt actgaaggcc atggaagaaa tcctgagaga
     6121 ccgtaacagg caactggaaa aaacagaatt aatcggttta tgccggaaag acatggagct
     6181 attgagcagt tattatcaga aggagattac ggctatgcac attgcggttc gtacttcctt
     6241 gcccgataat ccgttgttta ttgacgggaa tgccgaacaa ctgggaaaaa ccattatgag
     6301 tcttcttaac aatggtatgt atgccatagc caaaaaatat ggtaagaaag cctatccggc
     6361 agagattggc ctggcattgg aaagtaagga cggacaggca gtcattcgcc tatatgacaa
     6421 tggagtgggg atcgagcaga gtattctgga taaaatcttc gatccgttct ttactaccaa
     6481 aacaaccgga gaggcagcag gtatcggttt gtatctgagt aaggaaatca tattaaatca
     6541 ccatgggcag atagcagtac gttctgaaaa agatgaattg acagaattca ctatcactct
     6601 gccattgtgg gaggaaaagt cagtataaat aaacatagaa cagattgatt atgggaaaaa
     6661 acatttcaca agagaaacga attgaagagt tggaagcacg gctcaaagag caggaaaagc
     6721 tgggatcatt gggtttgttg agtgcaggca ttgcacacga gatacagaat cctttgaatt
     6781 ttgtcatcaa tttcagtaaa ctgtccggtc aattgttggc cgacctggcc gatagggtgg
     6841 atgaagcaaa agctcgtatt ccggaagcgg aactggaaga tatcaaagat atactttccg
     6901 ggctgagaga gaatgtggac aaaatcaaag agcatggtga tcgggctatc agcattattc
     6961 gtggtatttt gctttactcc agggggaaag aagacgaatt catgcctaca caaatacaaa
     7021 aattgactaa agaatatgtg tggctggctt atcatgccat gcgggccaat tataagaatt
     7081 tcaatattgc tatccgtgaa gattatgcta aagatatccc ctcgatccgg ctgatcccgc
     7141 aggatttcag tcgggcagtc ttgaatgtga tgaataatgc ctgctatgca gtatggaaaa
     7201 aatggcagaa tgctcccgaa ggatattccc ccgagataat ggtgacctta gaaaagttgg
     7261 ataaaagaat tgtactttct attcgtgata acggagaggg catggggccg gaggtcaaac
     7321 gaaaactatt tgactctttt ttcacaacaa aaccggtggg gcaggggaca ggccttggta
     7381 tggcaatcgt tcgtgatatt atagaaaaca aacaccatgg aaaagtattg tttgattcgg
     7441 tcctgcatga atatacttgt ttccggttta tcattcctat cgcatgaaac gctgtctgct
     7501 atatatcctt tgctgctttg gggttgtgca actgtcagct cagccggcgg ataacatccg
     7561 taattcgttt gtaaaggcgg aaacatttta taagagcgga gatatcgatg aagcttgtcg
     7621 tatcttggag gagaatctgt cgtcttttca aggtacgatg cataccgagg cgtgccgttt
     7681 ggctgcatta tgctgtttag ctttagaccg cttcccggaa gcggaaaagt atgtttcgct
     7741 gttattgaaa gacgaacctt attattatat ctcgcttcaa gatccggaac gctttgcgga
     7801 tatggtaagg aaacacaggg agactaaagt aactctggtc acagcctcac aacaggtaga
     7861 gaccccggaa gaagctccgg tgcctgttac tttaattacg gaggagatga tacgggctat
     7921 ccatgcccgg tgcctgcggg atgtactgat agcttatgtg cccggtatat ccggtttgtc
     7981 ttccaatgaa gagatgaatc tggctatgcg cggggtatat tctcccgaac aggagaacat
     8041 attgattatg caggatggac aacgtctgaa cagttatatt actaatgctg tttcgccgga
     8101 ttatggtatt agtctggcaa aagtcaaaca aatagaggtg ctgcgcggac cggcttcttc
     8161 gctttatggc agtgtggctt tgacagccgt gattaatata gttactaaag acggggtgga
     8221 tgttcgtaat ggttccatat ctgtcagtgc cggtaatcgg ggccagttgg ctgctgacct
     8281 gctattggga aagcacgaca tgaacatgga ctttatggca tggttctcct tgtaccgtgc
     8341 aacgggagaa tcggtttttg tcccggccga aaaacaatat gctctttacc ctagggacgg
     8401 attcatccgt ctggacaatt attcgggatt tcctgccatg gatggaggaa ttaaattgca
     8461 acgtggaaat ttgcttttta gtttcagtat gaattacgcg aagaaaaggc aaccttatag
     8521 catgtggctc ttttcttctc catattctta tgagcggttt cgtacttttg acggttccgg
     8581 cccgggatat tccagatggt cggcaagaga acaggctgtt tatagccgca cgtggcagcg
     8641 gatcactttc agtaccgcat tttataccga ttggaataaa aacgtacatt atgaaacctc
     8701 gggagatact ttacaagact atcctatttt tcctaactat gattatcagc ctattattta
     8761 tccgactcgc ggagcatttc aatacatccg ctggatggat tttaacgtag gctttaatgg
     8821 tcgtgtaaac tatgcctatg attgggggaa gctggggaaa ggcaatatgc ttggcggtgt
     8881 ggaatggaat cggtatacgc tttatgattc cgagtatttg gaaggtatga attttaaaga
     8941 gatcgtcagg acgtggatcg aaaaacgact ttacacggga cacgagatga acacggatgc
     9001 ctttcttcag attaaacaca acctgcatca aaattggatt gtcaatgccg gcatcaggta
     9061 tgactataaa cggcgaagta ataagcggac attacaggct ttttctcccc gtctgtcact
     9121 gatttatctc aggaacggat taaatatcaa agccagttat tccagagcat ttgtcgatgc
     9181 gccctattat tacagaaaca atgaaatgga tacctattcg ggtggcgaaa atctgcaagc
     9241 tgaatatcta agttcatatc aggtgacttg tgcttatcat cattcacctt cacatataga
     9301 tgtagagtgt aatttatttt ataatcgggc gtcccatttc ctgttcacac agccggaaac
     9361 acgtgtttat gaaaatgccg gttctctgga tatgggaggt gtcgaggtcg ttgcccgtta
     9421 taaggcagac cgactgagcc tggatggaaa cctgtgtttt cagaaagtat tggattatac
     9481 caattttttt gttaccgatg gatctgtgaa taacgtaccc ggcttttcta tgaatcttgt
     9541 agcaaactac tttttactta aaaagaaagt acagagctgg tctgcccatt taaaattgaa
     9601 ttgcagtagc cactgctaca ctcaggtaag tgtattggaa gatggactca atggagatgc
     9661 gacgaattac acagtccgtt tgcccggtta tgctgtcttt tctttcacta ccagatataa
     9721 gtataaaagg gtagaaggca gtctgggcat tgagaatctt ttcaataacc gatatgaatg
     9781 cggaggagcg actgttccta tccgccagaa aggaaggtgg atttccgcca gtatattgta
     9841 taatttctaa atcaaactaa taatgaaaac aaacattcaa gaaaatcttt ctcgatcact
     9901 ctttatttgg ggtgacaaac cggcggtcgt tgcaaaagac ggtaccgttt cttatcaaat
     9961 gctggaacgt tactctgcca atatagcaca atctatccgt caacgtttat cggtaactga
    10021 tccgtccgga cttcggaata tctgtatcgg agtttgtatg gaacgaaaca aaactttagt
    10081 acctgccatt ctggctattt tccggttagg ggcaacttat ttaccgatag atccctcgct
    10141 gccggataat cgtaaacggt atatggctga aaatgcggat atggttttgt tgttgaccga
    10201 ttcatcgaat gaagtaggtg gaattccgtc cgtccgccaa ctttacctga atggggagca
    10261 actatccgaa ccggttgttg gtgactatac tgaagttctt cccaatgatt gcgcctatat
    10321 tatatatact tccggaacaa caggcaatcc caaaggtgta cgtattagtt atcggaatct
    10381 ggatacattt acgaggaatc tggtagataa gaaattgtat catttgtctg atccggcaaa
    10441 caggtatctg gcgtttgcga gtatcagttt tgatgcttcc atattagaac tgatgatgtg
    10501 tattccggtc ggaggaacat tgatcctggc cggtgaggac gaacgcagag atatttcttt
    10561 actagacgaa ctgatcaggc gcgagaaggt gaatattgct tttttccctc cttcgttgct
    10621 gggcatgttt gccgaccttg actttccatc ctttaagact ctgctctttg gtgcggaggc
    10681 tattggtgaa aagttattta acaggctgaa acagcagcct taccggttga tgaatgtata
    10741 tggaccgaca gagaataccg tactcagtac catacggatt gtaggcaaag atacgtcgta
    10801 tgacgatatt ggctatccgc tcaagggaac tgtctgttat gttttgtctg aaaacctcca
    10861 acagacaact cttggggcta caggagaact ttgcttggga ggacctcagg tttcgctggg
    10921 atatattggg agtgttcagc tgaatgaaaa atcattcatc tcgtacgatg gagaacggtt
    10981 gtacaggaca ggtgacttgg tacagcagca accggacggt tcgatacggt ttatcgggcg
    11041 aaaagatact caggtcaaga tacgtggttt tcgtatcgaa ttgactgaaa tagcagaacg
    11101 attgaataga gatccggacg tggagagagc ccacgtagta gttgttgagc ggaatgggcg
    11161 tcaattattg ggagcttatt tgcaaccctc agtctccggt aactttcatc cggaagaggt
    11221 caaagagcgt ttgcgtgcag aacttcctta ctacatgata cccaatttat ggcaggtggt
    11281 agatcatttt cagcgtacta taaatgataa gattgatgtc cgggcgctcc cggcttttac
    11341 ttcattggag ttgaagtatg ttcctcctgt tcatccgggg gaggttatct tatgtggaat
    11401 tttgaaggaa atgttaggtt tgcctcaagt cagtgttgag gccgatttga ttgatgatct
    11461 gggattaact tcgctggata tgttgaggct tgttaccgag gccaataaaa aaggatgtcc
    11521 catcaacgta tctgcagttt atactgcccg taatctgcgc cgattattgc tcgttccgcg
    11581 gcaagaacct atctattggt acaggcagca aaacctgaag aaacccgtaa tcattctggt
    11641 ttgtggatct gcctatttta atcatttgta ctttaatttg gccgaccgcc tttatcccaa
    11701 atatgacttt ctagttgtag atgctatcta cgatcatttt aataaagtgg ctacggatat
    11761 tccggaactg ttggaatatt atgtccggac ggttcagcca atgatccggg agcgtaccgt
    11821 ctatgcgctt accggctttt gtatgggagc tgaactggct gtcggcctgg ccgaaatgtt
    11881 acatcgcttc atggggataa tgccaaaagt ttttgctctg gatggacagg cttggcaaaa
    11941 tccggctctc tggcaaaatt atcctttgtt ggtatttccc ggagatacag atgaaatggt
    12001 acgtgaacgg aacgaaatca taaatattta ttttcgaacc actcctaatc tgatttatca
    12061 gggagaggtt attgttttgc tgtccggatt gttccatcaa caggcgggat tgtctcctga
    12121 agagtcgtgg acggaggaaa gctatcgtat attccggaca gaatatgaca attgcgaaag
    12181 attatggaat aaatattatc cgaacgctcc tgttttgcga ttgccgacag atcattggca
    12241 ctttttagaa ggggaatcat tggaacaatt aataactgtg tttttgaagt agatttatgc
    12301 agactgaaaa cttcacttta ggtaagaaag agcttcttat tttgcttggc ttgactcttg
    12361 tactgccttt tccaatcaat tgggcattaa tcgaactgaa tccgttgact ctgatggcgg
    12421 gtgcagacga tgtgcccacc tggattggtt tcggcggcag ttatattgga ggaatcatcg
    12481 gagggatcat ctcgattatg attctgaaca agacacttca gcagacaggt gtacttcatc
    12541 acgatttgaa actcctgcag ttagatacca taatttatac tcagcaacaa gattggttta
    12601 ccggtttcaa acaagaactg gcagagaatc tcaaatctat tgatttgtat gtgttgaata
    12661 cggttgtttc gtctatatcc atgaaaaact atgcatatgc caaagaggtg ttgacagaaa
    12721 tcaataaagg gctcgaatat cagatggttg ccgcatcctt ttctttcact tctacgcatt
    12781 tatcatccga agaaaaaaag tatatgaatc tggtacgccg cgtacagact gaatatagct
    12841 cttttatcaa ggatattctt tactatattc ctttggcaga aacgatatct tccaggaaaa
    12901 aactaaacta tgatcagctg atggactata ctttgtccca atatgattat ttgcaaggtc
    12961 aggaagggga gtctacagct tcgggagcca tcataccgcg tgttatggaa atcgatccat
    13021 ctgatgatat acggaaagaa ctagaacgga taatggaaga aagattaacc gggcgtacct
    13081 atttgtatca cctgaagtca gatcttgcag aggctacgca tcaattaatt atttatgaag
    13141 agaaccgtat aaactctatt ctgcatctgt ctcttataca catctgacgc tgccgacgat
    13201 cttacgcgtg
//
