LOCUS       c00016_gnlPro..        13437 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBMANACO_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:22:58
            Original ID  :: gnl|Prokka|OBMANACO_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 13767
            Orig. end    :: 27204
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13437
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[23767:27136]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13369
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13437
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13437
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1041..2012
                     /locus_tag="ctg16_19"
                     /transl_table=11
                     /translation="MENRICILTLFVFLFLLSGESRAMVAMPDAWIRMMIGVNQKDWSL
                     LRERVQTDLHVPDREDVLMLIDYHRDDRMKCENLLRRLNGGEAYRYIMNKILPLLYVYR
                     EHSPVPIPDDKAAGVFLSTANVLPRVKFVHPQPVVPEEGKIETPVIIEQRTVLALKNNL
                     LYDLALAPNIEVEIPLNRRWSVNAEYKCPWWLNSSREFCYQLLSGGVEGRCWLGNRKRR
                     NRLAGHFIGAYAEGGIYDFQFKGDGYQGRYYAASGLTYGYAKQIARHLSFEFSLGIGYL
                     TTEYKKYTPYEGDLVWKSSARYNFIGPTKAKVSLVWLITTRR"
     CDS             2019..2960
                     /locus_tag="ctg16_20"
                     /transl_table=11
                     /translation="MKDITRLLCMVLLSFLVVAGCSRRDILDDYPVSGVEVRLDWNGVT
                     EKLPEGVRIIFYPKGDNGRKVDTYLPVKGGHVGVPPGIYSVVVYNYDTETVLVRGDESY
                     ETIETYTGLCNFGIAGTEKMVWGPEDFYTTCVDELMVEKSDESLILKLSPKLVVKTYHF
                     SIKVTGIKNISQVFGSVVGMADHYLLGKSFSLCDGCPIYFDVVRGKDTIEGSFTTFGIS
                     QIVRTRAENTEVSLNLLLLKVDDTVQEVKVDVTEVIHKSEAGGETDKPEIDVPIEDEIK
                     VDDVETPPDGNGGMNGDVDDWEDETDIVIPVE"
     CDS             complement(2990..3244)
                     /locus_tag="ctg16_21"
                     /transl_table=11
                     /translation="MFFANVPVPITSLPVLYAYTVNPLVFNTSKFTDVALVVLLTTLLN
                     PISAVFAAFSISSFCEQPVIANAATAANKIFFIIVCFIN"
     CDS             3447..4022
                     /locus_tag="ctg16_22"
                     /transl_table=11
                     /translation="LVAKANDLTKTDATVNFIFSHALTQVNFSIKSKVNDGLTYEVTDI
                     SISEVGNKATYNYGTGWSEPTATTSYTYPISTTATDNQVAGDASTVKILDTSNLMMLLP
                     QTLSNKVKILVKYKVMDKNGDTVYDDALTTGKEIVIGDGTTKWGMGKKVRYTLALTNNA
                     TSIGWAVTSVDEWTKDNEEDKGVETPAE"
     CDS             4185..5003
                     /locus_tag="ctg16_23"
                     /transl_table=11
                     /translation="MMCQNCKKSVPNAIFHVYHRRGFHYPAQKCEENFILFLIKGEMLV
                     NSREYAGTMLKAGEFMLQPISSKIEMLAMTDVECIYYQFNQPELFCDIRYNRIMKETDP
                     PLIPSPLPIIPELQHFLESARTYLSEKKICRDLLSLKRKELAFILGYFYSDYDLASLVH
                     PLSKYTSSFECFVYQNYKKVKTVEEFAKLGGYSQTTFRRIFDHVFHEPVYEWMLSRRKE
                     EIIYELQNTEATISEICYKFGFESLPHFSNFCKKSFGTSPRSIRLKRSSE"
     CDS             5151..7553
                     /locus_tag="ctg16_24"
                     /transl_table=11
                     /translation="LYRVALFCLFSMLSAVFMHAGEQQQQSKGIVTGRIVDQQKQPYYP
                     VAVAIEGVYIGGYTNENGVYHINDVPAGSQTIVVSGIGVKTKKVPIHVTAGKVNRIPDI
                     EIDTQAEELEEVQVIGKSEARRQQEQAYAISVLDIKKAYNSAAPLNKLLNNVSSVRIRE
                     EGGMGSNYNFSLNGFSGNQVKFFLDGIPMDNFGSSFNLANISANMAERVEVYKGVLPVN
                     LGADALGGAVNIVSRRDANYLDATYSFGSFNTHKVSVNGAYTHLKTGFTVRANAFYNYS
                     DNDYKVFVPIIDLATNKKIDERWVKRFNDAYRSGGIRLETGITNKPYADYLLAGIILSK
                     NDKDVQTGATMDAVYGGVKMKSESVIPSIRYKKDDLFLDGLSLSLYGTYNSVNTFNVDT
                     IARRYNWLGESVPSTSAGEGYYTDSKIKNREWLGNGNISYVIDGHQSLILNHVVSAMRR
                     TMNDKVRPDDENNNVPQQLTKNITGLGWQIRYDRWNANVFGKMYKLYSSTYKRLDEYTE
                     NARWEKVRDHKTNFGYGAAATYYILPSLQAKFSYEHAYRLPESIEMFGDGLIQQRNPDL
                     KPESSRNLNLGLSFIQTFGAHQLSADGNFIYRYTTDFILKGVSLTSNPTTGYENLGKVL
                     TKGVEAAVRYNYKDLFHTGAGFTYQDITDRQRYEKTKDSFVGEGITENITYKERLPNIP
                     YLFANADAGVRFHDLIWKNSVLTFDYNLNYIHSYYLSFPGLGAKSSKKVIPEQFSHDLA
                     LGYSMDNGKYSVVVECTNLTNQKLYDNYRLQKPGRAFNVKLRYFFSK"
     CDS             7563..8783
                     /locus_tag="ctg16_25"
                     /transl_table=11
                     /translation="MITMYRIYMYLLAACLLLGVTACEEEGLGNEETPFAPYVLSLGIN
                     SNGTTTYYVVTAPELMSGTINAVAKGIEQNGYRDYEQAGQTVFSIGGLGLTSATGIVRD
                     ANGYLTERGDFVFNSSLNAFTQMDGQNMIGLELPANKESGDQMTLYTVNISDVSITSQV
                     KAPVFPLNQLEWPSITGMCYSEGNVYVTYFPMNPSTFETLYTDTTFVAVYSYPDMQFKT
                     LMKDTRTGPAGSWNAFNGIFKVESGDMYIMSNSAIANGFSQSTKNAAFLRIPKGETYFD
                     DYYFDFETVSGGLKPAHIKYIGNGLVFAEVSTISPQTSADRWGDKSLKCCIIDLNNKTV
                     RDIKEIPVHNGDGGRRFAALVDGGYVYRPVTTSEGTYIYQVDPQAATAVRGAKVSTTFV
                     GGFFRLD"
     CDS             8790..9920
                     /locus_tag="ctg16_26"
                     /transl_table=11
                     /translation="MNKTFRKACAKLHLWLGLLSGIVVFIVCITGCMYAFKDEITDATQ
                     PWRFVAPLEKEFLPPSRLLAIADSVMGGASATAITYGERSDAAWVDYYQPEAGMSTVFI
                     NPYSGQVLKSVVNHNGDFDFFRLVLSGHRTLWLPREIGSPIVGYSVLIFLITLITGVIL
                     WWPRSRTRKALVQRLTLKRPFTFSRLNFDLHNVAGFYAALVLAVLCFTGLIFSLNWFSR
                     GVYSITSGGEELKPYVLPVSDTLQVVNRVTNPLDRLYTHLRLEEPAAKTFYFALPGQAD
                     GVYRVSVVHKRGSYYRTDNLFFDRYTLVSLKGAGSYAGKYTEASPADKFRRMNLEIHDG
                     RIWGLPGKIIMFLASLTGASLPVTGFIIWYRKRRKR"
     CDS             complement(10001..10639)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 61.6; E-value: 2.2e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_27"
                     /sec_met_domain="Fer4_7 (E-value: 2e-12, bitscore: 38.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.1e-19, bitscore: 61.6,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 8.7e-07, bitscore: 20.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDILNEQIINDGGEPIVFDHDCREGICGMCSLYINGHPHGPATG
                     ATTCQMYMRRFKDGDTITVEPWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSVNTGAPQD
                     ANAILISKDIADEAMDAAACIGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKVEAARR
                     AKAMLSKMDELGFGNCTNTRACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10786..12729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 197.1; E-value:
                     1.8e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_28"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.5e-61, bitscore:
                     197.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.6e-38,
                     bitscore: 121.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGQLAEKWSNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFARDYGGTLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQVQKGTVKLYTRYEMLDLVVIEGRARGIIARNLVTGEIERFAAHA
                     VVIGTGGYGNAFFLSTNAMGSNGSVAIQCYKKGAYFANPCFAQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKIEDAKALQAGTKKPTEIPDEDRDFYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEITDENPYK
                     TPMMIFPAIHYTMGGIWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQIQVPRFSTDLPEFAAAEKEVKDKIQKIKAVNGKHSVDSIHKKLGHI
                     MWDFVGMARTKESLQKALTGIEEVKKDFWTNVRIPGDVNELNVELEKALRLIDFIEVGM
                     LMARDGLNREESCGGHFRTEYQTPEGEALRDDKNFSYVACWKYTGENSEPELIKEDLNY
                     QFVKVQTRNYKS"
     CDS             complement(12767..13369)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_29"
                     /sec_met_domain="SucD_FumR (E-value: 3.2e-121, bitscore:
                     393.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLVAIISAEGYNLVCEFLGANWYALVATLGLAALFVIHIIYAFW
                     LTIQNRAARGSERYAVVDKPKTVEWASQNMLVLGIIVILGLGLHLFNFWAKMQLPELVH
                     NMGGVADTTYAADGVYHIMNTFSNPVYVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKI
                     WINRWKCISNIYSTIVVVCFALVVVVFFVKSLACGAC"
     CDS             complement(13341..13436)
                     /locus_tag="ctg16_30"
                     /transl_table=11
                     /translation="RKESGDERYRYRPCPVSNVSHGDEPCCDHLG"
ORIGIN
        1 agtgatgcta ctattgtggt ggagtctgcc gctaaaggcg gttcgctgat tacagcggat
       61 attgccggaa gctatcatcg cgattgtttt gcttttcccg ggcgggtcac ggacgaatat
      121 tcaaagggat gcaaccagtt gatacaagat aacaaagctg ttttgttgga gtctgcatcg
      181 gactttgtga aagcaatggg ctgggacagc gatttgaaaa gtgtcaagcc ggaaaccgta
      241 cagcgaaacc tctttccgga tctgtctgcc gaggaactga gaattgtcga tattctcgga
      301 aagctgggcg atctgcaaat aaacgcattg atggttcagg ccgatattcc cattaataag
      361 atcagtgcta ttctgtttga acttgaaatg aaaggcgtta ttcgggttct ggcaggagga
      421 gtttaccagt tactcagata aaaaaggcaa aaaaaaagga gtcacgcctg actccaacct
      481 tttgttaacc ttaaatctaa tactatgaaa aaaatcactg tacaaatgta ggtttctctt
      541 atctattatc caaatattct tcttaatatt ggctctcttt gagtttcttt tactgttttt
      601 tactgttctc ttttacaagt gggctaaaca tcggcaataa ctcttttgct tttaacctcc
      661 cttcactttc cttgaaaagc tttcttcatt aggttcccac tcttcatagt ctgacatggg
      721 gatgtcggga ggtttaacat gggggtgtcg gacggtctga cacccccatg tcggacaacg
      781 tatgtcgtag agacagatct attttcttgc cgggataagt aagtcaggtg gtaagtaaga
      841 agatttaagc aacggcagta cccactttta gaggccgaca ttggccggaa agctacccaa
      901 gtgcgggggt gcttcaccgc caaacttgca aattcctttc aatcgtttca cagaagcatt
      961 cagagcttgt atttagcttt gattaaatta ttatgtatcg atttgaactt ctatatttgt
     1021 attgcacaaa cagacaaatt atggaaaacc gtatctgcat actgaccctt tttgtttttc
     1081 tctttctgct ttcgggagaa agccgggcca tggtagcaat gccggatgcc tggatcagaa
     1141 tgatgattgg tgtaaaccag aaggattggt cactgttacg tgaaagagtg cagactgacc
     1201 tccacgttcc ggatcgtgag gatgtgctga tgttgatcga ttatcaccgc gatgaccgga
     1261 tgaaatgtga gaatttatta cgcaggttga acggtggaga agcataccgc tatattatga
     1321 ataaaatctt accgctttta tatgtataca gagaacattc acctgtaccc ataccggatg
     1381 ataaagctgc cggtgtgttt ttgagtacgg cgaatgtatt gccccgagtg aaattcgtac
     1441 atcctcagcc ggtggtcccg gaagagggaa aaatagaaac accagtaata atagaacaga
     1501 gaacagtgct tgcactgaaa aacaacctgc tatacgacct ggcattggca ccgaatatag
     1561 aggtggaaat accattgaac agacgctggt cggtcaatgc cgagtataaa tgtccgtggt
     1621 ggctcaatag tagccgggag ttttgctatc aattgctttc gggaggcgtt gaaggtcgtt
     1681 gctggttggg caaccggaag cggaggaacc gcttggcggg acatttcatt ggagcttatg
     1741 ccgaaggggg aatttatgat ttccagttta aaggagacgg ctatcaagga agatattatg
     1801 cagcttcagg gctgacttat ggatatgcaa agcagattgc acggcatctc tcgtttgaat
     1861 tcagcctggg cataggttat ctgactacgg agtacaagaa gtacactcct tatgagggag
     1921 acttggtttg gaaaagtagt gcacgctata acttcatagg ccctaccaag gcaaaagtat
     1981 ctttggtgtg gcttataaca acaaggagat gataatgaat gaaagatata acaaggttgc
     2041 tttgcatggt tctcctctcg tttctggtgg tagcgggatg cagccggcga gatattctgg
     2101 acgattatcc ggtgagtggt gtggaagtgc ggctggattg gaacggagtg acggagaagt
     2161 tgccggaagg agttcggatt attttctatc cgaaagggga caacggacgt aaagtagaca
     2221 cctatctgcc tgtgaaagga gggcatgtag gagttccccc tggtatctat tccgtggtag
     2281 tctacaatta tgatacggaa accgtattgg tccggggtga tgagtcatac gagacgattg
     2341 aaacttatac cggtctttgt aattttggaa ttgccggtac agagaagatg gtttgggggc
     2401 ctgaggactt ttatacgact tgtgtggacg agttgatggt ggaaaaaagc gatgaatctt
     2461 tgatactgaa actatctccg aagctggtag tgaaaactta ccacttcagc attaaagtaa
     2521 ccgggattaa aaatatatcc caagtctttg gcagtgtagt ggggatggcc gatcattatt
     2581 tgttaggcaa aagttttagt ttgtgtgacg gctgtccgat ctattttgat gtagttaggg
     2641 gaaaagatac aatcgaggga agttttacga cttttggaat ctctcagatc gtacgtactc
     2701 gtgccgagaa tacggaagta tctttgaatt tgctactgct gaaggtggat gatacagtgc
     2761 aggaagtgaa ggttgatgta accgaagtga tacacaaatc ggaggctggt ggagaaactg
     2821 ataaaccgga aattgatgtt cctatcgaag atgaaataaa agtagatgat gtggaaactc
     2881 ctccggatgg taacggtggt atgaatgggg atgtggatga ttgggaggat gaaactgata
     2941 tagtgatacc ggtggaatga caccggtagg cagataaaag agataattat taatttataa
     3001 aacatactat tatgaaaaag attttatttg cggcagttgc tgcattggca atcacaggtt
     3061 gctcacagaa tgaggagatt gagaaggcgg cgaaaactgc ggagattggg ttcaatagcg
     3121 tagtcagtaa aacgacaaga gctacatcag taaatttaga tgtattgaaa accaatggat
     3181 ttacggtata tgcatataat actggtaatg atgtaatggg tactggtaca ttggcgaaaa
     3241 acattataga taaagagcct attacatgga atggtacaga cagctggctt gggagtaaaa
     3301 cctattattg gcctaacagt gataaaatac aattttttgc atattcctca aagaatgtta
     3361 cggggttaac tgctcaatct agtgatgttt atcctacaat agtcgattat gaagtgcttg
     3421 ctgatgctac aaagcaagaa gatctgttgg ttgcaaaagc taatgattta actaaaactg
     3481 atgccacagt aaactttata ttctcacatg ctcttactca ggttaacttt tcaataaagt
     3541 ctaaggttaa tgatgggttg acttatgagg taacagatat ttctattagc gaggtcggta
     3601 ataaagcaac ttataattat ggtactggct ggagtgagcc aactgctact acttcttata
     3661 cttatccaat aagtacaact gctactgata accaagtggc tggagatgcg agtactgtga
     3721 aaatcttaga tacttctaat ttgatgatgt tgttgccaca gactttgtct aataaagtaa
     3781 agatacttgt gaagtataaa gtaatggata agaatggtga tactgtttac gatgatgctc
     3841 ttactactgg caaagaaatt gtgattggcg atggaactac taaatgggga atgggtaaga
     3901 aagtacgtta tacattggcg ttgactaaca atgctacttc cataggttgg gctgtgacaa
     3961 gtgttgatga atggacaaaa gataatgagg aggataaggg tgtcgagact cctgctgagt
     4021 gaattttgta aaactataga gcattaaaat gatattcctt ggaaacttaa gttaattaag
     4081 ttttcaggga atatttttta tatttaaata attctcttac atttgtcgta aacatacaaa
     4141 caaacacacc cgtatatatg cccagctccg tttgtggaga tcccatgatg tgtcagaact
     4201 gcaaaaagtc agttcctaat gccattttcc atgtttacca tagacgtggt ttccattatc
     4261 ctgcacaaaa atgtgaggag aatttcattt tgttccttat caagggagaa atgctggtga
     4321 atagtcggga gtatgccgga acgatgctta aggccggaga atttatgctt cagcccatca
     4381 gttcgaaaat agaaatgctg gccatgaccg atgtggaatg tatctattat cagtttaatc
     4441 aacctgaatt gttttgtgat atccggtata atcgtatcat gaaggagact gatcctccgt
     4501 taattccctc acccttaccc attattcccg aacttcaaca ttttcttgag tctgcacgta
     4561 cttatctgag cgaaaagaag atttgtcggg atctcttatc attaaagcgg aaagagcttg
     4621 ctttcatact cggttatttt tattcggatt atgacctggc ttccctggta catcctctct
     4681 caaaatatac ctcttcgttt gagtgctttg tatatcagaa ctataagaag gtgaagactg
     4741 ttgaagagtt tgctaaactt ggaggatata gtcagactac attcaggagg attttcgatc
     4801 atgtttttca tgagccggtg tatgagtgga tgcttagtcg ccgcaaagag gagatcattt
     4861 acgaacttca gaatacagag gctaccatct ctgaaatctg ttataaattc gggttcgaat
     4921 ctttaccgca tttctcaaac ttctgtaaaa agtcatttgg tacctcgcca cgcagcattc
     4981 gattgaagcg ttcatccgaa tgagacaggc ctctggaaga gagatttttt tatcattgta
     5041 tttaggtatc ggagtttcgg tgaataccta aatatggtga ttgtcgtccg gtgtcgatat
     5101 acgtaccttt gcggactaat taaacagagt gattaatgaa ccacaaagtg ttgtacagag
     5161 tagctttatt ctgtcttttt tctatgctgt cagccgtttt tatgcatgcc ggcgaacagc
     5221 aacaacaaag taaaggtata gtgacaggtc gaatcgtcga ccaacagaag caaccttact
     5281 atccggttgc agttgccatt gaaggtgttt atattggcgg atataccaac gagaatggag
     5341 tttatcatat caatgatgtg ccggcgggca gtcagacgat agttgtatcg ggcataggag
     5401 tgaaaactaa aaaggtgccg atacatgtga ctgccggaaa agtgaaccgg attccagaca
     5461 tagagatcga tacccaggcg gaagagctgg aagaagtaca ggtgattgga aaatctgaag
     5521 ctcgccggca gcaggagcag gcgtatgcca tatcggtact cgacatcaag aaagcgtata
     5581 atagcgctgc acctctcaac aaattattga acaatgtgtc gagtgtccgt atccgtgagg
     5641 aaggtggtat ggggtctaac tataatttca gcctgaacgg attttcgggc aatcaggtga
     5701 aattcttttt ggacggaata ccgatggata atttcggatc gtcttttaac ctcgctaata
     5761 tctcggctaa catggctgag cgtgtagagg tatataaagg ggtattacct gtaaatctgg
     5821 gtgccgatgc cttgggagga gcggtgaata tcgtcagccg tagagatgcc aattatctgg
     5881 atgcgaccta ttcttttggc tctttcaata ctcataaagt ctcggtgaat ggagcctata
     5941 cccatctgaa aacaggtttc acggtgcgtg ccaatgcttt ctataactat tccgacaatg
     6001 attataaagt gtttgtgccc atcatcgatc tggctaccaa taagaagata gacgagcggt
     6061 gggtaaagcg ctttaatgat gcctaccggt caggaggtat ccgcctggag acgggaataa
     6121 ccaataagcc ttatgccgac tatctgcttg caggcattat tctttcgaag aatgataaag
     6181 atgtacagac tggtgctacg atggatgccg tttacggtgg cgtaaaaatg aagagtgaat
     6241 ctgtgatccc ttctattcgt tataagaaag acgatctgtt tcttgacgga ctttcgctgt
     6301 cactttacgg aacgtataat tctgtaaata ctttcaatgt ggataccatc gcccgccgtt
     6361 acaactggtt gggagaatcc gttccgtcta cttctgcagg agaagggtat tatacggatt
     6421 ccaagataaa gaaccgcgaa tggttaggaa acggaaacat cagttacgtg atcgacggtc
     6481 accaatcatt gatactgaac cacgtggttt ctgctatgcg gagaaccatg aatgataaag
     6541 tacggccgga tgatgaaaac aacaatgtac ctcagcaact gactaagaat atcacaggct
     6601 tgggatggca gatccgctat gatcgttgga atgccaatgt attcggaaag atgtataagt
     6661 tgtacagttc tacctataag cggttggatg aatatacaga gaatgcccgt tgggaaaaag
     6721 tgcgggatca taaaaccaat ttcggatacg gtgcggcggc tacttattat atcttaccct
     6781 ctttgcaggc taagttctct tacgagcatg cctatcgttt gccggaaagt atcgaaatgt
     6841 ttggggacgg gttgattcag cagcggaatc cggatttaaa accggaaagc agccggaatt
     6901 tgaatctggg gttgagcttc attcaaactt tcggggccca tcaactttcg gctgatggaa
     6961 acttcattta tcgttatacg acagacttta tcctgaaagg ggtcagcctg accagtaatc
     7021 cgactaccgg ttacgagaat ctgggtaagg tgttgacaaa gggtgttgag gctgctgtca
     7081 gatataacta taaagatctg ttccatacgg gagccggttt tacttaccag gacattaccg
     7141 accggcagcg atatgagaag acaaaggaca gctttgtcgg cgaaggtatc acagagaata
     7201 ttacctataa agagcgtttg ccgaacatcc cttatttgtt tgctaatgcc gatgcagggg
     7261 ttcgttttca cgatttgatt tggaaaaact ctgtgctgac atttgactat aatcttaatt
     7321 atattcattc gtattatctt tcgttcccgg gcttgggtgc aaaaagctct aaaaaagtaa
     7381 tccccgaaca gttctcacac gatctggcat tggggtattc aatggacaac ggaaagtata
     7441 gtgtggttgt ggagtgtacc aatctgacca atcaaaagct gtatgataac taccgcttgc
     7501 agaaacccgg gcgtgccttt aatgtgaaac tgagatattt ctttagtaaa taaaaaagtc
     7561 tgatgattac aatgtatcga atttatatgt atctccttgc tgcctgcctt ttattgggtg
     7621 tcacggcatg tgaagaagaa ggattgggaa atgaggaaac tccttttgct ccctatgtac
     7681 tcagcctggg tatcaattcc aatgggacta ccacttatta tgtggttact gcacccgaat
     7741 taatgtccgg aacaatcaac gcggtggcca aaggtatcga acaaaacgga tatcgtgatt
     7801 atgaacaggc cggacaaacg gtgttcagta ttggcggact gggactgacc agtgcaaccg
     7861 gaattgtacg tgatgcaaac ggctatctga cggagcgtgg agactttgtc tttaacagtt
     7921 cgctgaatgc gtttacacaa atggacgggc agaacatgat cggccttgaa cttccggcta
     7981 ataaggagag tggggaccaa atgaccttat ataccgtaaa tatcagtgat gtttctatca
     8041 cttctcaggt caaagctccg gtatttccgc tgaatcaact cgaatggccg agtatcacgg
     8101 gtatgtgtta tagtgaaggt aatgtgtacg ttacttattt tccgatgaac ccttccactt
     8161 ttgagacttt atataccgat actacttttg ttgcggtata ctcttatccg gatatgcagt
     8221 ttaaaacatt gatgaaagat acgcgtaccg gtcctgccgg ttcgtggaat gcatttaacg
     8281 gtatttttaa ggtagagtcc ggcgatatgt acatcatgtc taattctgcc attgccaacg
     8341 ggttttcaca aagtaccaag aatgctgctt tccttcgtat ccctaaaggt gagacgtatt
     8401 ttgatgacta ctattttgac tttgagacgg tttcgggagg attgaaacct gcccatatca
     8461 aatatatcgg taatggtctg gtatttgccg aggtcagcac catcagtccg cagacatccg
     8521 ccgaccgttg gggagataag agtttgaaat gctgcattat cgatcttaat aataaaacgg
     8581 tacgtgacat taaagagatt ccggtgcata acggagatgg cggacggcgt tttgccgctc
     8641 tggtagacgg aggttatgtt tatcgtccgg tcactacttc agagggtact tacatttatc
     8701 aggtagatcc tcaggcggct actgcggtca ggggagctaa agtttcaacc acgtttgtcg
     8761 gcggtttctt ccgtctggat tgataagaga tgaataagac ttttcggaag gcttgtgcga
     8821 aacttcattt atggcttgga ttgctttcgg gtattgtggt attcatagtc tgcatcaccg
     8881 gctgcatgta tgcatttaaa gacgaaatta ccgatgccac acaaccttgg cgctttgtag
     8941 ctccattgga gaaagagttt ttgccgcctt cccgcttact tgcgatagcg gattctgtca
     9001 tgggaggagc ttcggccaca gccatcactt acggtgaaag atcggatgcg gcctgggtgg
     9061 actactatca gccggaagca gggatgagta ctgtttttat caatccgtat agcggacagg
     9121 tattgaagtc ggtagtgaat cataacggtg atttcgattt cttccggttg gtgcttagcg
     9181 ggcatcgcac tttatggctc cccagggaga tcgggagtcc gattgttggt tacagtgtat
     9241 tgattttcct catcaccctg ataacgggag tgatactttg gtggcccaga agcaggacac
     9301 gcaaggcact tgtgcaacgg ttgactctga aacgcccctt taccttttca aggcttaact
     9361 tcgacctgca taatgttgcg ggtttttatg ctgcattggt gctggccgta ttatgtttta
     9421 ccggattgat atttagcctg aattggttta gcagaggcgt gtacagcatc acttcgggtg
     9481 gtgaagagtt gaagccctac gttttaccgg tatccgatac attgcaggtt gtcaatcgtg
     9541 tgacaaaccc tttggacaga ctttatactc atctacggct tgaagaacct gctgccaaga
     9601 ccttttattt tgctttaccc ggacaagccg atggtgttta ccgggtcagt gttgtacata
     9661 aaagagggtc ttactaccgt accgataatt tgttttttga ccggtataca ctggtttctt
     9721 tgaaaggagc cggttcttat gccggtaaat ataccgaggc ctctcccgcc gataagttcc
     9781 gtcgtatgaa tctggagatt catgacgggc gcatctgggg gcttcccggt aaaattataa
     9841 tgttccttgc gagcctgacg ggtgcttcac ttcctgtgac cggctttatc atttggtatc
     9901 gtaagcgccg taagagataa cactgctctc catatacaaa aattccccac cgataccggt
     9961 ggggaatttt cctacttatt aatcaaatgc taagttgtgc ttagtctttc agttttgcga
    10021 tgatgaaatc gcggttcaaa cgagcgatgt tgctgattga aatgttcttc ggacactctg
    10081 cttcacaagc acgtgtgttt gtacagttac cgaatcccag ttcgtccatc ttagaaagca
    10141 tagcttttgc acggcgtgct gcttctactt ttccttgtgg aaggaggttc agctggctga
    10201 ccttagctga tacgaacaac atggcagaac cattcttaca agcagctaca caagcaccgc
    10261 aaccgataca tgcagcggca tccatagcct cgtcggcgat atccttagag ataaggatag
    10321 cgttggcatc ctgaggagca cctgtgttta cgcttacgta accaccggcc tgcatgatct
    10381 tgtcataagc cgaacggtca accatcaagt cacggattac cgggaaaccg gcagaacgcc
    10441 aaggttcaac tgtgatggtg tctccatctt tgaagcgacg catatacatc tggcaggtag
    10501 tagcacctgt cgcaggtccg tgcgggtgtc cgttgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcagtcatgg tcgaatacga taggttcgcc accgtcatta ataatctgtt
    10621 cgttcaggat atccagcatt tcgaggaacg acgtatcgcc cgggatatct ttcatttgat
    10681 atgtttcaaa agcacctttt gctttcgggc ctttctggcg ccataccttc agtgtgaatg
    10741 atatattttt atccattttt gttttccttt aattgattag ccgaattatg acttgtagtt
    10801 acgagtctga acttttacga actggtagtt caaatcttct ttgatcaact ccggttctga
    10861 attttcaccg gtgtatttcc agcaagctac gtatgagaag ttcttatcgt cacgtaacgc
    10921 ttcaccttcc ggggtctggt attcggtacg gaagtgtcca ccgcaagatt cttcacggtt
    10981 caaaccgtcg cgagccatca acatgcctac ttcaatgaag tcgatcagac gaagtgcttt
    11041 ttccagttct acgttcagtt cgtttacatc acccgggatg cgaacgttgg tccagaaatc
    11101 tttcttcacc tcttcaatgc ctgtcagggc tttctgcaga gattcttttg tacgggccat
    11161 acctacgaag tcccacatga tgtgacccag tttcttgtgg atagagtcaa cagagtgttt
    11221 tccgtttacg gctttgatct tctggatctt atctttcact tccttttcgg ctgcagcaaa
    11281 ttccggcagg tcggtagaga agcgcggaac ctgaatctga tcggccaggt agttctggat
    11341 ggtgtaaggc aatacgaagt atccgtcagc cagaccctgc atcaatgcag atgcacccaa
    11401 gcggttagca ccgtggtcgg agaagttggc ttcaccgata gcgaacagac ccgggataga
    11461 agtcatcaat tcataatcaa cccagatacc acccatggtg tagtggatag cggggaatat
    11521 catcatcgga gtcttgtacg ggttctcgtc agtgatttct tcgtacatgt cgaagaggtt
    11581 accataacgg gcacgaacca cgtcctcacc cagacgatcg atagcatatt tgaaatcgag
    11641 gaagacggcc aaaccggtat tgttcacacc gaaaccggca tcacaacgtt ctttggctgc
    11701 acgtgaagca acgtcacgcg gaacaaggtt accgaatgcc gggtaacggc gttccaaata
    11761 gaagtcacgg tcttcatcag gaatttcggt cggcttttta gtgcctgcct gcaatgcttt
    11821 ggcatcttca atcttcttcg gaacccagat gcgaccgtcg ttacgaagtg attcagacat
    11881 caatgtcagc ttagactgct tgtcaccgtg tacggggata caagtcgggt gaatctgagc
    11941 gaaacaagga ttggcaaaat aagcaccttt cttatagcac tggatggcaa ctgaaccgtt
    12001 ggaacccata gcgttggtag aaaggaagaa tgcgtttccg taaccacctg taccgataac
    12061 tacagcgtga gcagcgaaac gttcgatttc accggttacg aggttacggg caatgatacc
    12121 gcgcgcacgt ccttcaatta caacgaggtc gagcatttcg taacgagtgt aaagtttaac
    12181 agtacctttt tgtacctgac ggctcaatgc tgaataagcg cccagcaaca gctgctgtcc
    12241 ggtctggccg cgggcataga acgtacggga tacctgtgca ccaccgaatg aacggttgtc
    12301 aagtgtgcca ccgtaatcgc gtgcgaaagg tacaccctgt gctacgcatt ggtcgatgat
    12361 agcgtttgat acctcagcca gacggtaaac gttggcttcg cgtgcacggt agtcaccgcc
    12421 tttgattgta tcgtagaaaa gacggtaaac cgagtcacca tcattttgat agtttttagc
    12481 tgcgttgata ccaccctgtg ctgcaataga gtgagcacgg cggggtgaat cctgaataca
    12541 gaaattgaat actctgaaac ccatttcgcc cagagaagcg gcagcagatg ctccggcaag
    12601 tccggtacct acaacgataa tgtcaaggcg acgtttgttg gcagggttaa caagtttttg
    12661 atgagcctta tagttactcc atttttcggc gagctggcct tcaggaattt ttgaatctat
    12721 cttagtcata atgctattta caatttaatc atttacaatt tacaatttag caagcaccgc
    12781 atgccaacga tttaacgaag aatacgacta ctaccagagc aaagcataca acaacgatgg
    12841 ttgaatagat gttggagatg catttccagc ggttgatcca aatcttgttg ttccagccca
    12901 aagattgcat agagctccag aaaccatgag tcaggtggaa ccaaagggcg cccagccaaa
    12961 cgaggtacag cactacatat acagggttag agaaagtgtt catgatgtga taaacaccat
    13021 cagcagcata agttgtgtct gctactcctc ccatgttgtg caccaattct ggtaactgca
    13081 ttttagccca gaagttaaag aggtgaaggc ccaaacctaa gataacgatg atacccagca
    13141 ccaacatgtt ttgtgatgcc cattccacgg ttttaggttt gtcaactacg gcgtaacgtt
    13201 cgctaccacg tgctgcgcga ttctgtattg tcagccagaa agcgtagata atgtgaatca
    13261 cgaagagggc agccaggccc agcgtagcta ccaacgcata ccagtttgct cccaggaact
    13321 cacaaaccaa gttgtaaccc tcagccgaga tgatcgcaac aaggttcatc gccatgtgaa
    13381 acgttagaaa caggacaagg gcgataccgg taacgctcat caccactttc cttccta
//
