LOCUS       c00107_gnlPro..        11086 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBMANACO_107.
ACCESSION   c00107_gnlPro..
VERSION     c00107_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:22:58
            Original ID  :: gnl|Prokka|OBMANACO_107
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11086
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11086
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[170:6772]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      171..6772
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11086
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11086
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..119
                     /locus_tag="ctg107_1"
                     /transl_table=11
                     /translation="DRSVSRGLGDVYKRQRRGDSIKSVRKVMYVFVQIEDMI"
     CDS             171..1973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg107_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-217, bitscore:
                     712.2, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKEQLGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKKEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGELDGQHLDLID
                     AMIKSADESVSDEEVSKIENRACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ANRTQLFKDAAKLIVENTYKYYRDGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAIAHEAEADFKMDDIDMLSRKSPCLCKVAPNTQKYHIQDVNRAGGIMGIMGQLAKAG
                     LIDTSVVRIDGMTLGEAIDKYDITSPNVCEEAIKKYKSAAAGKFNLVLGSQDVYYKELD
                     TDRAEGCIRDIEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACNGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGNIGKIKDGDIIEINIPERTINVRLTDEELAARPMTPVTRERY
                     VPKSLKAYASMVSSADKGAVRLID"
     CDS             2029..3726
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg107_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.1e-48, bitscore:
                     151.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDIISGGEALMRSLEYHGVKTIFGYPGGSIMPVFDALYDHRET
                     LNHILVRHEQGAAHAAQGFARASGEVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTAFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVPWAVARAFYIAKSGRPGPVVLD
                     FAKNAQVEKAEYMPAKLDFIRSYVPVPETDPEAVKAAAELINGAERPLVLVGQGVELGN
                     AQQELRAFIEKADMPAGCTLLGLSALPTEHPLNKGMLGMHGNLGPNMNTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEINKNVHADVAVLGNCKETLSAVTALLQPNE
                     HKEWLDSFLPYEQVEEEKVIRPELHPMGDTLSMGEVVRAVSDATNHEAILVTDVGQNQM
                     MSARYFKYSKDRSMITSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIIVLNNNFLGNVRQWQAMFFNRKYSFTPMLNPDYIKIASAYDIPAKRVF
                     TREELADAIDEMIATDGPFLLEACVIEEGNVLPMTPPGGSVNQMLLEC"
     CDS             3740..4300
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg107_4"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-19, bitscore: 58.4,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTLYTLIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVVKQIEKKIDVLQAHYFTEDEIYFHEIALYKVSMPEFQSQPE
                     ASKVIRRYNARIVEVNPVFAIVEKNGISEEITSLYEELSALNCVLQFVRSGRVAITTSC
                     FERVNEFLADRETKYNLSKKEEK"
     CDS             4301..5044
                     /locus_tag="ctg107_5"
                     /transl_table=11
                     /translation="MSDDKKIGSYKFIAEPFHVDFNGRLTMGVLGNHLLNCAGFHASER
                     GFGIATLNEDNYTWVLSRLAIDLEEMPYQYEEFTVQTWVENVYRLFTDRNFAIIDKDGK
                     KIGYARSVWAMINLNTRKPADLLTLHGGSIVDYVCDEPCPIEKPSRIKVATDQPCAKLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIDLYKSKRIQRFEMAYVAESYYGDELSFFEEEV
                     SENEYHVEIKKNGSEVVCRAKVKFV"
     CDS             5062..5646
                     /locus_tag="ctg107_6"
                     /transl_table=11
                     /translation="MKKIVFLLLLCVACCMNAQEFHLIPKVGLNLANTTGEVDSKVRPG
                     LNIGLGGDVMLTERFGIETGVYYSMQGSKYKGGGVSYTDKLDYINVPVYAKEFIYKGLY
                     VFGGPQFSFNVNSENKSSSDYGTTVIGMNVIRKFDCGVGLGAGYQFERGLLISLNYNIG
                     LINVNKSWASDSNPKANNSVVQLNVGWRFAL"
     CDS             5729..6772
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg107_7"
                     /sec_met_domain="IlvN (E-value: 7.2e-46, bitscore: 145.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 7.3e-41, bitscore: 129.1,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVTENVVTREEFPLEKAREVLKNETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACEKGTIIMCLLSDAAVMS
                     VWPTIKPYLTAGKALYFSHGFAITWSDRTGVVPQKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAIYQDATGRAMERTIALGIGVGSGYLFETTFVREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVQKLYNSVKTGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             6974..8893
                     /locus_tag="ctg107_8"
                     /transl_table=11
                     /translation="MKNRIYTMKGMLATLLGAFLLGYAVTGCIDEKDHYKPDDKTSGVP
                     NSFDFATTQDVQLDLKYDVPVKDYQVLFELYFENPLTTDAEGQVVKRTDITPKVVRMTD
                     GTGKYRAKETVPAYGEEVYIYTSSVGVPMLYKTKIVGNTITADINWDTAAEESVQTRAE
                     GEYQTVPQGFYTLGSWNVKGRPNYLDSEGVIELTPSFYQTINQTIPEGGNCPPKYRQSA
                     DIVINDELGAEVKVRFVGGTSSAYSAFGYYCYPEGAAKKQIENAKKYVVFPNTKTGVGI
                     KGGECVKLHYIDENGEDQGTTFPKGTKIGWFISNNAFTKQGEKVGSVGKGLGMFYSTTA
                     LNSDGRTHTAAFKINDFIVLSFEDWNSQDYNDVMFNIWSNPIEAIAPDVPSVDPIDPDD
                     ASVAYRMTYKGILAFEDNWPSKGDYDLNDVIVKYSSILEFNTKNQVLSAEDTFTAMWSG
                     ALFKNGFAYQLNTDRSNVECSILEGKSGWDKQGLDKDLEQATISVFANAIEETGENTKT
                     STFKIQNKFKQPVDHETFGVAPYNPFIFLHQNTDKNRTEVHLVNHGPTSKENMDLFNTQ
                     QDLSDKDKGIYYVSDQNYPFAIHLSDVESFSTTEKEAIDKSYPRFASWAQSGGTTDKDW
                     YLKK"
     CDS             complement(9006..10910)
                     /locus_tag="ctg107_9"
                     /transl_table=11
                     /translation="MNDNKIKSSSPLSDLQHQQLLLRMEYEYEKEEFRRQTETMGIARK
                     VKRGLCWYPVGTGRSFYNSLNQLVIEIERKEDKDIEHVFEFGRPVCFFEQGYDGKIHYF
                     NSICTVSYADEERMVVAVPGAGSLLEIQGAERLGVQLYFDETSYRTMFEALEDVIRAKG
                     NRLAELRDILLSKQPSRWRETYPVRFPWLNSTQEAAVNKVLCAKDVAIVHGPPGTGKTT
                     TLVEAIYETLHRENQVLVCAQSNTAVDWIAEKLVDRGVPVLRIGNPSRVNDKMFSFTYE
                     RRFEEHPAYTELWGIRKSIREMGNRMRKSSYSEREAARSRINHLRERATELEIQINEDL
                     FSGARVIASTLVSSNHRILTGRRFTTLFIDEAAQALEAACWIAIRKADRVIFAGDHCQL
                     PPTIKCIEAARNGLEQTLMEKVAANKQETVSLLKVQYRMHQSIMQFSSEWFYQDELQAA
                     PEVTNRGILDLDLPMSWIDTSEMEFHEEFVGESFGRINKPEANLLLQELEAYIRKIGEK
                     RVLEERIDFGLISPYKAQVQYLRGKLKGCLFFRPFRSQITIHTVDGFQGQERDVIFISL
                     VRANEDGQIGFLNDLRRMNVAITRARMKLVILGDAVTMSKHAFYKKLIGYIRHISQGL"
ORIGIN
        1 gagatcgctc agtgtctcgt gggctcggag atgtgtataa gagacagcgt cgtggtgatt
       61 ccatcaagag cgtgagaaag gttatgtatg tattcgtaca gatagaagat atgatttaga
      121 gcctttctca ctacagtggg gaaggctctt tacttaaaag gaatattgaa atgaaaaagc
      181 agttacgcag ttcgttcagc acacagggtc gccgcatggc aggcgcccgg gcactttggg
      241 cagccaatgg tatgaaaaaa gagcaattag gcaaacctat cattgccatc gtcaattcgt
      301 ttactcagtt tgttccggga catgtacatc tacatgaaat aggtcagctg gtgaaaaaag
      361 aaattgagaa gctgggatgc tttgctgcgg aattcaatac gattgccatt gatgatggca
      421 ttgccatggg acatgatgga atgctttatt cccttccttc ccgggatatc attgccgata
      481 gtgtggaata tatggtgaat gcccataaag cggatgccat ggtatgtatc agcaattgtg
      541 acaaaatcac tccggggatg ttgatggcgg ctatgagact gaatattcct actgtatttg
      601 tatccggagg cccgatggaa gccggtgaac tggatggaca gcatttggac ctgattgatg
      661 cgatgattaa gtcggccgac gaaagtgtga gtgatgaaga agtctccaag atcgagaatc
      721 gggcctgtcc cacttgcgga tgttgttcgg gaatgtttac cgccaattcg atgaactgcc
      781 tgaacgaagc gatcggtctg gctcttcccg gaaacggaac gattgtggcg acccatgcca
      841 accgtaccca attgttcaaa gatgctgcga aactgattgt agaaaatacc tataaatatt
      901 atcgggacgg tgatgaaagc gtacttcccc ggagcattgc cacccgtgag gcattcctga
      961 atgccatgac gctggacatc gcgatgggag gatctaccaa tacggtactt cacctgctgg
     1021 cgatagccca tgaagcggag gcggacttta aaatggacga tatcgatatg ctttcacgca
     1081 agagcccatg cttgtgtaag gtggcgccga atacacagaa gtatcatatt caggatgtaa
     1141 accgtgccgg aggtatcatg gggattatgg gacaacttgc caaagccgga ttgatcgata
     1201 cgtctgtagt gcgtatcgac gggatgacat tgggtgaggc gatagataaa tatgatataa
     1261 ctagcccgaa cgtatgtgaa gaggctatta aaaagtataa gagtgcggct gccggaaagt
     1321 tcaatctggt gctcggctct caggacgtct attataaaga gctggatacg gaccgtgccg
     1381 aagggtgcat tcgagacata gagcacgcat atagcaaaga cggaggactg gccgtactga
     1441 aaggaaatat tgcccaggat ggttgtgtgg tgaaaacggc cggagtggac gagagcatct
     1501 ggaagtttac cggtccggca aaggtgttcg attcacagga agcagcctgc aatgggatac
     1561 tcggaggaaa agttgtcagc ggagatgtag tcgtcatcac gcacgagggt ccgaagggag
     1621 gtcccggtat gcaggaaatg ctttatccta cctcttatat caaatcgcgc cacttgggca
     1681 aggagtgtgc gctgataacc gacggccgtt tcagcggagg tacatcggga ctcagcatcg
     1741 ggcatatctc tcccgaagca gcagccggag gtaatatcgg aaagattaag gatggtgata
     1801 tcatcgaaat caatatcccc gaacggacta tcaacgtgcg actgaccgat gaagaactgg
     1861 ctgcacgtcc gatgactccg gtcactcgtg aacgctatgt gcctaaaagt cttaaagcgt
     1921 atgccagcat ggtaagctct gccgataaag gagcggtgag actgattgat taaccacaga
     1981 gttgtttcaa tcgtaaattg taaatcgtaa aatcgtaaat tttagtacat gagtaaagat
     2041 ataatttcag gcggtgaagc attaatgcgt tctttggaat atcatggtgt aaagacgatc
     2101 tttggttatc ccggaggatc tatcatgccc gtattcgatg ccttatacga tcatagagag
     2161 actttgaatc atattttggt tcgccacgaa caaggggcgg cacatgcggc tcagggattt
     2221 gcccgtgctt cgggtgaggt cggagtttgc ctggtgacga gcggccccgg tgctaccaat
     2281 accataaccg gtattgcaga tgcaatgatc gacagtacac cgattgtagt cattgccgga
     2341 caggtgggaa cagctttttt ggggacagat gcttttcagg aggtcgactt ggtaggcatc
     2401 acgcagccaa ttacaaaatg gagttatcag atccgtcgtg ccgaagatgt gccatgggcg
     2461 gtggcccgcg ccttttatat agcgaaaagc ggacgcccgg gaccggtagt gctcgacttt
     2521 gcaaaaaatg cccaggtaga gaaagccgaa tatatgcctg cgaaactcga tttcatacgc
     2581 agttacgtgc ctgtacccga gactgacccg gaggccgtga aagcggctgc cgaattaatt
     2641 aacggtgcag agcgcccgtt ggtattggtg gggcaaggtg tggaactggg caacgcacaa
     2701 caggaattgc gtgctttcat cgaaaaggca gatatgcccg ccggatgtac gttgttggga
     2761 ctgtcggctt tgccaaccga gcatcctttg aacaaaggta tgctgggaat gcacggtaat
     2821 ctcggaccga atatgaacac caataaatgt gatgtcctga ttgctgtcgg catgcgtttt
     2881 gacgaccgtg tgaccggaaa cctggctacg tacgccaagc aggcgaaagt gattcatttt
     2941 gatatcgatc cggctgaaat taataagaat gtacatgcag atgtagcggt tctgggtaac
     3001 tgtaaagaga cgctctctgc tgttacggca ttgctgcagc ccaacgagca taaagaatgg
     3061 ctggatagtt tcctgcctta tgaacaggtg gaagaagaaa aggtaatccg tccagaattg
     3121 catccgatgg gagatacgct ttcgatgggg gaagtggtgc gtgcggtaag cgatgcgacc
     3181 aatcatgaag cgatattggt gaccgatgtc ggtcaaaacc agatgatgtc tgcccgatac
     3241 tttaaatatt caaaagaccg gagcatgatt acttccggag gacttggtac catgggattc
     3301 gggttgccgg ctgctatcgg tgcaaccttt ggccgaccgg accgtacggt ttgtgtattt
     3361 atgggtgacg gtggtctgca aatgaacatt caggagttgg gaaccattat ggaacagaag
     3421 gcaccggtta aaattatcgt attaaacaat aatttcctgg gcaatgtacg ccaatggcag
     3481 gcaatgttct tcaaccgtaa atactcgttt acacccatgc tgaatcccga ttatattaag
     3541 attgcttctg cttatgatat accggccaaa agagtcttta cccgtgaaga actggctgat
     3601 gcgattgacg agatgattgc gacagacggt ccgttcctgt tggaagcttg tgtgattgaa
     3661 gagggaaatg tgttgccgat gacccctccg ggaggttcag ttaaccagat gttgttggaa
     3721 tgctaataag ttaggaatta tggataagac attatataca ttaattgttc attcagagaa
     3781 ctttgccgga ttgctgaatc aggttacggc agtatttacc cgtcggcaga ttaatataga
     3841 aagcctgaat gtttcggctt catctatcaa gggggtgcat aaatatacta ttacggcttg
     3901 gaccgataaa gatacgatag agaaggttgt caaacagatt gagaagaaga tcgatgtgct
     3961 tcaggcacat tatttcactg aagatgaaat ctattttcat gaaatagctc tttataaggt
     4021 gtctatgccc gaatttcagt cacagccgga ggcttcgaag gtgattcgtc gctataatgc
     4081 acggattgtg gaagtgaatc cggtatttgc catcgtcgag aaaaatggaa tcagtgaaga
     4141 aattacttct ctctacgaag agttgagtgc attgaattgt gtgttgcaat ttgtgcgttc
     4201 gggacgtgtg gcaatcacta ccagttgctt tgaacgtgtg aacgagtttc tggcagatcg
     4261 tgagaccaaa tataacttaa gcaagaaaga ggaaaagtga atgagtgacg ataagaagat
     4321 agggagttat aagtttattg cggagccttt tcatgtagac ttcaacggac gtttgacaat
     4381 gggggtgctt ggtaaccatc tgttgaactg tgccggcttt catgccagtg aacgcggctt
     4441 tggaatcgct acattgaatg aggacaatta tacatgggta ttgtctcgtc tggccatcga
     4501 tctggaagag atgccttatc aatatgagga gtttactgta cagacatggg tggagaatgt
     4561 atatcgtctt tttactgatc gtaattttgc cattatagac aaggacggca agaagatcgg
     4621 atatgcccgt tcggtatggg ccatgattaa tttaaatacc cgcaagccgg ctgatttgct
     4681 gacgttgcat ggcggtagta ttgtggacta tgtatgtgac gaaccttgtc cgatcgaaaa
     4741 gccttcgcgt atcaaagtgg ctactgacca accttgtgct aagttgacag ctaaatacag
     4801 cgatatcgac atcaatggtc atgtgaacag cattcgttat atagaacata tcctcgattt
     4861 gtttccgatc gatttgtata aatcgaaacg gattcagcga tttgaaatgg cctatgtggc
     4921 agaaagttat tatggcgacg agctttcttt ttttgaagag gaagtaagtg agaatgaata
     4981 tcacgtcgag attaagaaaa acggcagtga agttgtatgc cgggcaaaag tgaagtttgt
     5041 gtagtttaaa atgtgattaa aatgaagaag attgtttttc ttttgctgct ctgtgttgct
     5101 tgctgcatga atgcacagga gtttcatctg attccgaagg tcggtttgaa tctggcaaat
     5161 actaccggag aggtggattc taaagtgcgt cccggactca atatcggtct gggaggtgat
     5221 gtcatgctga ccgaacgctt tggaatagaa acaggagtgt attactccat gcagggaagc
     5281 aaatataaag ggggcggagt ctcttatacg gataaactgg attatatcaa tgttccggta
     5341 tatgcgaaag aatttatata taaggggctg tatgtgtttg gagggccgca gttcagtttc
     5401 aatgtgaact cagagaacaa atcatcctct gactatggta ccacagtcat aggcatgaat
     5461 gtgattcgca agtttgattg tggagtgggg cttggagccg gttatcagtt tgaacgtggt
     5521 ctgctgatct ctctaaacta taacatcgga ctgattaacg taaacaaatc ttgggcaagc
     5581 gactctaatc ctaaagcaaa caatagtgtg gtccagctaa atgtcggttg gcgttttgca
     5641 ctgtaagata aagaatataa gtttaattat taataatcgg ttttgttttc gtccgaacgg
     5701 aacaagactt ttaaaacaaa aaagaaaaat ggcacaattg aattttggcg gtgttacgga
     5761 aaatgtagta acccgtgaag aatttccttt ggaaaaagct cgtgaggtat tgaagaatga
     5821 aacaatcgct gttatcggtt acggtgtgca gggaccgggt caatcactga acctgcgcga
     5881 taatggcttc aatgtaatcg ttggtcagcg tccgggaaaa acatatgaaa aagcagtggc
     5941 agacggctgg gttccgggtg aaacactgtt cggcatcgaa gaggcatgcg agaaaggtac
     6001 tattattatg tgtctgttgt cagatgcagc cgtaatgtct gtatggccta ctatcaaacc
     6061 ttacctgact gccgggaaag cactctattt ctctcacggt ttcgcaatta catggagcga
     6121 tcgcaccggt gttgttccac agaaagatat cgatgtcatt atggtcgctc cgaagggttc
     6181 gggtacttca ctccgtacga tgttccttga aggtcgcgga ctgaactctt cgtatgccat
     6241 ctatcaggat gctaccggca gagctatgga gagaaccatc gcattgggta tcggcgtagg
     6301 ttccggatat ctgtttgaaa cgacttttgt ccgtgaagct acttccgacc tgacaggtga
     6361 acgtggttcg ctgatgggag ctatacaagg tttgctgttg gctcagtatg aggttttgcg
     6421 tgagaacggt catactccat ctgaggcatt taacgaaacg gttgaggagt taactcagtc
     6481 attgatgccg ctgtttgcta agaatggtat ggactggatg tatgccaact gctcgactac
     6541 ggctcagcgt ggtgctcttg actggatggg cccgttccac gatgctatta aacccgttgt
     6601 tcagaaatta tataatagtg taaagaccgg taacgaggca cagatctcta tcgactctaa
     6661 ttcaaaaccg gattatcgcg agaaactgga ggccgaactg aaggcattgc gtgaaagcga
     6721 aatgtggcag acagctgtaa ccgttcgtaa acttcgtccg gagaataatt gatctgaata
     6781 gattatacaa cttatgataa aaggaggaaa ctgctgtttc ctccttttat tttgcttgta
     6841 attagtgttt tgtgtctgag ttgttagaat ggtatgttgt agaatatgaa aaatagatag
     6901 attgtttgga tagataaatc aagttaaata tatatctttg tgccctgatc aaacaacaaa
     6961 caatattatc aatatgaaaa atcgtattta tacaatgaaa gggatgctgg ctacattact
     7021 gggtgctttt ttactagggt atgcagtaac aggttgtatt gatgaaaaag atcattataa
     7081 accggacgat aaaacatcag gagtgcctaa ctcttttgat tttgcgacta ctcaggatgt
     7141 ccaattggat ctaaagtatg atgttcctgt gaaagattat caggttttgt ttgaactcta
     7201 ttttgaaaat ccgttgacga cagatgccga agggcaggtg gtgaaacgta ctgatatcac
     7261 tcccaaggtt gtgagaatga ctgatggaac cggaaaatat cgtgccaagg agacggtacc
     7321 ggcctatggg gaggaggttt atatctatac ttcttctgtc ggagtgccga tgttgtataa
     7381 gactaaaatt gtagggaata cgattacagc cgatataaat tgggatacgg cggcagagga
     7441 gtctgttcag acacgtgccg aaggcgagta tcagacagtg cctcagggat tttatacttt
     7501 aggcagttgg aacgtgaagg gacggcctaa ttatctggat agtgaagggg taatagaatt
     7561 gactccttcg ttttatcaga cgattaatca aacaattccg gaaggtggaa attgtcctcc
     7621 gaaatatcgg caatcggctg acattgtcat caacgatgaa ttgggagccg aagtaaaggt
     7681 acgttttgtc ggaggtacaa gttctgcgta cagtgctttc ggatattatt gttatccgga
     7741 aggagcggct aaaaaacaga tagagaatgc taagaaatat gtggtctttc ccaatacgaa
     7801 aaccggagtc ggcataaaag gcggagagtg tgtgaagctg cattatatcg atgaaaatgg
     7861 cgaagaccaa gggactactt ttccaaaagg aaccaagatc ggttggttta tcagtaataa
     7921 tgcatttacg aaacagggtg aaaaggtcgg tagtgttggt aaaggactcg gaatgtttta
     7981 ttcgaccact gccttgaatt cggatggtcg tacccatacg gctgcattca agatcaatga
     8041 ttttatagtt ttatcatttg aagattggaa cagtcaggat tacaatgatg tgatgtttaa
     8101 catctggtct aatccgattg aagctattgc tccggatgta ccttcggtag atccgataga
     8161 tccggatgat gcgtcggttg cttatcgcat gacttataaa ggtattttgg cttttgaaga
     8221 caattggcct tctaagggtg attacgattt gaacgatgta attgtgaaat atagctctat
     8281 attagagttc aataccaaga atcaggtgct ttccgctgaa gatacgttta cggcaatgtg
     8341 gtccggagct ctctttaaga atggctttgc ctatcagttg aataccgata gaagcaatgt
     8401 ggaatgcagc atattggaag gaaagtcggg atgggacaaa caaggattag acaaagactt
     8461 ggagcaggcc accatttcgg tgtttgccaa tgcgattgaa gagacgggag agaacactaa
     8521 gacttctact tttaagattc agaacaaatt taaacagcca gtcgatcatg aaactttcgg
     8581 agtggcaccc tacaatcctt ttatcttctt gcatcagaat acggacaaga accgtacaga
     8641 ggtgcatttg gtaaatcacg gaccaacctc taaagaaaat atggatctgt tcaataccca
     8701 gcaggatttg tcggataaag ataaaggcat ctattatgtg tccgatcaga attatccgtt
     8761 tgccattcat ctgtctgatg tcgagtcatt cagtacaacg gagaaagaag ctattgataa
     8821 gtcgtatcct cgttttgctt catgggcaca atccggcgga acgacagata aggattggta
     8881 tttgaagaaa taagttgatg tcgtttttat gctatagaac aaggggctgt ccgaaaatcc
     8941 gacagcccct tgttttatgg ttttaaatgg aaacagaagt tacgactgaa ataaggagat
     9001 cggcatcaga gtccttggct gatgtgccgg atatatccga tcaatttctt atagaaagca
     9061 tgcttgctca ttgtgaccgc atctcctaat ataaccagtt tcattcgggc gcgggtgatg
     9121 gctacgttca ttcggcgcaa gtcgttgaga aaaccgattt gtccatcttc gttagcgcgg
     9181 acgaggctga tgaaaatgac atcacgctcc tgtccctgaa aaccatctac tgtatggatg
     9241 gtgatctggc tacggaaggg gcggaagaat aaacagcctt tgagttttcc tctcagatac
     9301 tgtacctgcg ctttgtaagg ggagataagg ccgaagtcta tacgctcttc caatacacgc
     9361 ttctcgccga ttttgcggat gtatgcttca agttcttgca acaataagtt tgcttccggt
     9421 ttattgatgc ggccgaagct ttctcctaca aattcttcgt ggaactccat ttcggaggtg
     9481 tcaatccaac tcatgggcag gtccagatcg agtatccccc ggttggtcac ttcgggggcg
     9541 gcttgtagtt cgtcttggta gaaccattcg gaggagaatt gcataataga ctgatgcatg
     9601 cggtactgaa ctttcaggag tgagaccgtt tcctgcttgt tggctgctac tttttccatt
     9661 aatgtttgtt ccaacccgtt ccgggccgct tctatgcatt ttattgtggg aggcaactga
     9721 caatggtctc cggcaaagat gacgcggtct gcttttcgga tggctatcca acaggcagcc
     9781 tcaagggctt gtgctgcctc gtcgataaag agtgtggtaa atcgccggcc ggtcaggata
     9841 cggtggttac tgctgaccaa tgtggaagcg atgacccgtg cccccgaaaa cagatcttca
     9901 ttgatttgta tttccagctc cgtggcacgc tccctcagat gattgatgcg gctgcgtgca
     9961 gcttcccgtt ccgagtaact gcttttgcgc atccggtttc ccatttcccg gatcgattta
    10021 cgtattcccc agagttcggt ataggccgga tgctcctcga aacggcgttc gtaagtaaat
    10081 gaaaacatct tgtcatttac ccggctcgga ttgccaatac gcaatacagg tactccgcgg
    10141 tctaccagct tctcggcaat ccagtcgacg gccgtgttgc tttgtgcaca gaccaggact
    10201 tgattttcgc ggtgcagggt ctcgtagatg gcttctacaa gagtggtggt ctttccggtc
    10261 cccggaggac cgtgaacgat ggctacgtct ttggcgcaaa gtactttgtt gactgctgct
    10321 tcctgagtgc tgttcaacca agggaaacgg accggatagg tttccctcca gcgggagggt
    10381 tgcttgctta gcaatatatc acgtagttcg gcaaggcggt tgcctttggc gcgaatcaca
    10441 tcttccagcg cttcgaacat ggtacgatag gaggtttcat caaaatagag ttgtactccc
    10501 agacgttctg ctccttgtat ttcaagtaga gatccggcac cgggtacggc tactaccata
    10561 cgctcttcgt cggcataact gactgtacag atggaattga aataatgtat ttttccgtca
    10621 tatccctgtt cgaaaaagca aaccggacgt ccgaattcga atacatgttc gatgtcttta
    10681 tcttctttcc tttctatttc gatgaccaat tggttcagtg aattgtagaa actccgtcct
    10741 gtcccgaccg gataccagca gagccctcgt tttactttcc gtgcaatgcc catcgtctct
    10801 gtctgccggc ggaattcttc tttctcgtat tcatattcca tgcgtagcaa aagttgctga
    10861 tgctgaagat cactgagtgg agaagaagac tttattttat tatcattcat cttgcttggc
    10921 tgtaagttat atgctaagaa ctatagttat ggaatgacta caaattacga aatttatgca
    10981 gaacctgtca cagtcatttg tagcttgtag catctgattt gtagcagcta tacttatagc
    11041 ctgtctctta tacacatctc cgagcccacg agacactgag cgatct
//
