LOCUS       c00144_gnlPro..        10018 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBJAAMNO_144.
ACCESSION   c00144_gnlPro..
VERSION     c00144_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:38:25
            Original ID  :: gnl|Prokka|HBJAAMNO_144
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10018
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10018
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2871:7728]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2872..7728
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..10018
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10018
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             197..766
                     /locus_tag="ctg144_1"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(740..1846)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.6e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg144_2"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-17, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFL
                     NEWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYI
                     GAMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQT
                     EILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVE
                     LFLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIER
                     LLQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNH
                     IPQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(1843..2868)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg144_3"
                     /sec_met_domain="MR_MLE_C (E-value: 3.3e-30, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(2872..3696)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg144_4"
                     /sec_met_domain="ECH_1 (E-value: 1.6e-82, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(3700..5367)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg144_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.4e-09, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(5387..6499)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg144_6"
                     /sec_met_domain="Chorismate_bind (E-value: 2.4e-58,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(6496..7728)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg144_7"
                     /sec_met_domain="HBT (E-value: 1.6e-17, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEILPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(7813..8175)
                     /locus_tag="ctg144_8"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(8246..10018)
                     /locus_tag="ctg144_9"
                     /transl_table=11
                     /translation="STPIKSSAASDVYKRQVFNQLLFADKTIENDSLYTSEYISRIYMA
                     EPERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPK
                     HLLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFK
                     EEAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKD
                     IAKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAI
                     PYLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRES
                     IISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILF
                     VLWRIWRHMIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFS
                     EKDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFA
                     RMIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTG
                     MTPYEFKKTQESLG"
ORIGIN
        1 tgcaattaca ctaatagtac aactgaggta atcgaaaagg gacaggtata acatactttt
       61 ttttatttta ttttttaagc tatcttattt tccacagctt cataccaaaa acaaaaaaag
      121 aaagaaaatt ttaggaaatg ctgattttct tattatatat ttgcagtaaa atgaaaaact
      181 acagaatctc aaaataatga aaatatcttt ttccagacag actaaagaaa gagctttcaa
      241 acaactttac gaggattatt atgccccttt ctgcctgtat gcaaaaagat ttgtagatga
      301 taaagaagtc cgcgaggaca ttgtttcgga tgtattcacc tccctatggg acaagttgga
      361 taccgactct ttcgatttgc aatcagagac agcattggga tatataaaaa tgtgtgtaaa
      421 aaacagctgt ttgaactttc tgaaacatca ggagtatgaa tggagttatg ccgaaaatat
      481 ccaaaagaaa gctcctctat atgaaacaga aacagatagt gtatatacac ttgatgagtt
      541 ataccgaatg ctatacgaaa cattaaataa gcttccggaa aactatcgca ccgtatttat
      601 gaaaagtttc tttgaaggca aaacacatgc ggaaattgcc gaagaaatga atctcagcgt
      661 aaaatccatt aatcggtata aacaaaaaac aatggaactc ctgcggaacg agttgaaaga
      721 ttacctcccg ctgtttttat tattcctgtc tcccgagcaa ctgtaagctc tctgctaaaa
      781 cacggcactc tttacgatta atcttcccat ttcccgtttg aggaatatga tttaccgtat
      841 aaatatattt aggacgataa taagatgcta agactgattc caatttagtc cctagcgcac
      901 ttatctccat ctgcccttct atcaataaag taacagcctg ccccaaacgc cgatccggaa
      961 cggaagtgat cacaaacggt acagggatag acgactgaag taacctttcg atctcttctg
     1021 cctgcacttt aattcctccg ctattgatta cattatcctt tcttcccaga atcgtaaaac
     1081 taccgtccgg ataaatgcgg gcaatatcat ttgtctgcag agtatcatcg caaacaagcg
     1141 gagcattaat catcaaagta ttttctgaag acaaaaacaa ctctacggat gaaaaaggat
     1201 aataacgatc ggatgctgct gcgccattca gacggcgaag agcgatgtga gaaagggttt
     1261 ccgtcatccc gtaagttgaa taaacagcat tggacagatt tctgattttt tcctctaaag
     1321 ccttgtcaac tgctccgcct cctataatta aaatctccgt ttgctttaat ttctctttct
     1381 cttcgggtat ctgaaatgta ttatacacct gcaaaggcac catagccgca aaccttaaag
     1441 gagtgtccac atctgccaat ggatgaccgg aagcccgacg tactataaga ttcaacccgg
     1501 caatcaaaga acggacgact accatcatcg ccccgatata gcgaaggttc atacacaata
     1561 atgccgtttc accctgcttt aaatccagaa actcacaagt caggcgtgca ctctgtatca
     1621 tctgatcttt gcgaacaagc aattctttag gtgcccccgt agaaccggaa gtatgtacag
     1681 tgatcacagg atcatcatta aaccattcgt ttagaaaaag atacaagtcc catatagcag
     1741 aagggtggtt tccctcacct tctgctacaa ggctatgtat atcgcccgga gtatattcct
     1801 ttccctccag caacaaacgc tgtttttgtc ggtcgaatat catcatttac aaaaccacaa
     1861 acaatctttt ctgatttcaa gaggcatctc tacattatct gtaaagagta acccggtgcc
     1921 taacccttgc ggcaatggat tctgaaaagt agcacaccat tgagcgatag cattcagacc
     1981 gatattagac tccagagcag aagttatcca ccaaccgata ttcagtttct ccgcttctgc
     2041 aatccactcc tcgccaccgg ctaatccgcc atgaagagaa ggtttgataa taatatattg
     2101 cggacggata gccgaaagta atctttgctt ttcttcccag gtattatagc ctatcagttc
     2161 ctcatccaaa gctatcggca aaggagattc ggaagtaaga cgtgccattt cttcccattg
     2221 tccggcacga atgggctgtt ctatcgaatg taagtccagt tcggacaagc gtttcaattt
     2281 ctccatcgca tctgttggtg agaatgctcc gttggcatct acacgcaatt ctatttcttt
     2341 agaagaatag tgagagcgga tatgttggag taaagccagt tcttcttcaa agttgatggc
     2401 accgatcttc aactttatac agcggaatcc cgcctccatc ttcttctcta tctgagcaag
     2461 cattctattg aagtcaccca tccagataag cccgtttatc ggaatacctg cttccccacg
     2521 tgagaagggt gtatcccaca aagcccagct tccttcaaaa aagtgacgaa tggctgtctc
     2581 caagccaaaa aggatggaag ggtacttgca tagagcttcc atgtccagct tacctccctg
     2641 attctctacc tgccggcaga ttttagccag cacttcctcg taatcgggaa gatcatcaca
     2701 gctaagattt ggcagaggag cgcactcccc gatccctacc caattgggaa attcgggagc
     2761 agtaaaatga agataccaga cttttcgcgt tgtgtatgtg cctcgtgaag ttccggccgg
     2821 ctgcttgaaa tgaagcaccc gcggaataat gtctattttg caatccattg tttaagggaa
     2881 cttcggatat ttcttaaagt taggtttacg tttctccaga aatgcattct ttccttcctg
     2941 agcctcatcc gtcagatagt aaagcaaggt cgcatcccct gccagctcct gaatacctgc
     3001 ctggccgtcc agttcggcat tcaatccggc tttaatcatc cgcaaggcca acggactgag
     3061 cagcatcatt tcttccgccc attgcacata ctcatcctcc agttgctcca atggaactac
     3121 tttattcacc aatcccatat ccaacgcttc ctgcgcattg tatttccggc aaaggaacca
     3181 tatctcacgt gccttcttct gaccgacgac acgagccaga taagaggctc cgaaacctgc
     3241 atcaaagcta cctacgcgag gaccggtctg tccgaagatc gcattctccg aagcaatcga
     3301 taaatcgcaa actacatgaa gcacgtgtcc gccaccaatg gcaaatccat ttacggcagc
     3361 aattaccggt ttcggaatgc tgcggatttg tttctgtaca tccagaacac tcagacgggg
     3421 aacaccgtcc ttgccgatat agccgccacg ccctttcaca ttctggtcac cgcccgaaca
     3481 gaaagccttg tcaccagctc ccgtaatcac gatcacatca atatccgctt cttcccggca
     3541 aatgcgcaat gcgtcactca tttcagccgt tgtagtcgga gtaaatgcat ttcgatagcg
     3601 ttcacggtta atggtgatgc gggcaatccc attatagtaa tcaaagagga tatcttcgta
     3661 ttctctgatg gttgtccatt ctctttgtgt tgacataatc tatttttgtt ttagttgatg
     3721 ataataatct ttcagtatac gtgcatcttt atttttattg ctgaatactt ccatcagaac
     3781 cggttgttcc atggcttccg gttgtgtgaa ggttttcatc gcttcggcaa gctgttcttc
     3841 attctctacc cgttgataaa ggaatccgcg ttcttccgcc catcctttgg cagatgtctt
     3901 gtgaacggct gtaatatact tgtgcgatgt acccgacata tccagtccgg gtaatgtatg
     3961 gaaaatctcc cctcctccgt tattcagcaa aagaatgcgt agattgggac ggacattgat
     4021 gttccacaaa gcattcatat cataaaagaa actaaggtca cctataacta taaaatttag
     4081 tttatccgaa ccggcggcat atcccactgc cgtggacaac gagccttcga tgccgcttgt
     4141 accccgatta cagcatacct caatcgtaga aggaacctgg tataactgag catagcggat
     4201 aacagaacta tttgccagat gcaatgcaca tgattccggc aatgctttta tcaaagcacc
     4261 gatagccgac atttccgaat atccgaactc cggttcggga atggtcttgc aataattctc
     4321 ccatacacgg ggatactccg gcacgcggtt atccagcaat ggagctattt tctccagaaa
     4381 ctcaaacggg tccatttcga tgacggtagt cagagaaccg taaaggtcaa ccacttctcc
     4441 atcagcagac acatgccaat gttctttagg cggatgctgc cgaagatatt ttttcaaccg
     4501 cttggaaacc acatgtccgc cataagtaat caataactcg ggagtcatct ggccggtttt
     4561 ctcttcgggc atcgcataaa gcgccgcatc aaaattcttc actggaatac cgggtactgt
     4621 ctgattaccg atatgctcgg tcagccacac gaaatgttta tataacaatt tggtatgccg
     4681 tttctcaaac aagtaaatca agttcatctg tccgacaata atcatccgct tctgatatct
     4741 gttcaagcgt tcgatcaggt cattgtaatc ccggtcgtat acattcagcc cctgatagcg
     4801 cgtaatgaca cgtacttcgg gaagcgactc caccgtaaac tggaacaaag gttcggatat
     4861 aggaatatta atatgtaccg gaccttttcc atgatggttg gtttccagca aggcttcatt
     4921 caccaagcgg ttacagtacc attcatcctc ttctgtctga atctccggaa ggtttaccga
     4981 cttcttcacc aatgtctgaa aaacaccggg ctgcggcaat gtctgtcccg ccatctgtcc
     5041 aatccaggca gcaggccgat cggcagagat aacaactaaa ggtatattct gataatacgc
     5101 ttctgccaca gcaggatgaa gattgagcaa cgctgtaccg gaagtacagc aaacggcagc
     5161 aggatgcccg ccattcagcg caagaccaat cgcaaaataa ccggcactcc gttcatccgt
     5221 catagcataa caagtaaaac ccggatgagt agacagcgta tgcacaatag gtgcattacg
     5281 gctaccggga cataacacta ctttcgtaat tccatgcgcc tcaagcagcg cgaccaactg
     5341 gagtatattt ttcttgtccg aatacatatt gatagtgatt agcttgttag tgattcatca
     5401 ttattggagc agacacaaga atacgcctca tggtctgcaa tttcttttcc gtttcctgcc
     5461 attcatcatt caactctgaa gaggctaaca atccgccacc ggcatacagt gtcaattgct
     5521 cgtcttcaat gtgcatgcaa cgcagattca catacaaatc tgtgcgtccc tccggatcga
     5581 gccaaccgat aaaaccggaa taatacttac gatcgtaccc ttcattttcc aaaatgaacc
     5641 ggtaggcttc ttctttaggc agtccgcaca cggcaggagt cggatgcagg actttcagaa
     5701 ggtctcccag atttttatta tctttcaaag agaaatggaa atcagttttc agatgtgaca
     5761 aggcaccggc ataagccgga taaggtccgc tctctgtgga gcgaatgccc agcgaaagaa
     5821 gctgccgacg gatataggac gccacataat cctgctcctg acggtttttg tcatcccata
     5881 cttgcggaag tttaccattc tgcaaaggtt gagttcctgc cagggcaact gtgttccatt
     5941 catttttttc gcccgacaat ataatttcgg gggtacttcc cagccacacg cccgtctgag
     6001 gagtataaca cagatagata taggaatgaa tataacgttg acaagctgca cgaaaaacag
     6061 ctgaagggga aaactccgga ttctttccaa tagtgagact acgggaaagc accagtttat
     6121 caaaggtagc atcacgcaag gcttcaataa atgtatgaaa acaggtcgca tacttcccag
     6181 tacaaagggt atgaaaagat tcctccggat aactttgcaa gtcctgctct tcctctgcca
     6241 cgatttccat aggcaacggt tgtccagtcc tgtcggactg tatcaacaca atcggacatg
     6301 acttatctat acggaacgga gcaatcacaa atcctctttg tccattcagt tctttcaaat
     6361 cgaaaatcaa gcggacagct ccgacatctt ctgtcaacag acgaggatac ttctccccgg
     6421 gaacacgata aacagcaaag ggctgtttcc gctgaataag tgcatcaata gttgtcaagt
     6481 tacttttttc gtcaatcatc tttttttcat cacactgttg accacccgta tagaggacac
     6541 cagtttattg gttgaagtaa aaacgtccac attccataca tgggaggaac gtcctttgtg
     6601 tacaatcgtc gctactgcac gtactgtatc accttcgtgc gcagaagata tatgatttcc
     6661 gctgacctgc attcctacca caatttcatc cggctgacag agaatcatcg agccgagtcc
     6721 ggcaactgtt tctcccaatg caagcgtagc tccaccgtgc aaaataccga acggctgacg
     6781 ggtacggtga tctaccggca tcgtcgcctc tacacggtct tcgtcggcat atgtatattg
     6841 gatacccaga ttacccatca atgcgtgacg cgcctgtgca ttcaactggt ccaaaggaat
     6901 ctctgcagcg cgaacttccg ctattatcgc cttttcgaca gccagagcca ctccgtcttc
     6961 ctcattggaa gctgtcacat aatccgcaca gacctttacc gaatcctgcg aatgccccat
     7021 cgccactccc agtcctgcca gctgaatcat cgttacatcg cacacaccgt ctcctatagc
     7081 gatgacttct tcacgcttca catccagttc ttccaataaa gctcccaatg tgttggcttt
     7141 atcaatcgca cacggcacta cttccagaaa ataaggttcg gaacggaaaa catccaaagc
     7201 tccgttcaac cgtctcttcc agtgtccttc cagactaacc aacgcttcct cgtcatcgct
     7261 gacaagcata cacttacacg gagcaaagtc aattgctaca gaaaattcct cttccttgat
     7321 cactttcaaa ttattcaagc gagcttcatt ctggatatgt tcattctccg gagtgtcagt
     7381 aatgatcgta tcatcatggt aagtgaacag tgcgaaatta ttttttcttg ccttcttttc
     7441 cagataaggc aatatttccg gattaatcct ccgctcaaac agtatttctc cgttttgagc
     7501 attaattatc tggcaaccat tataagaaag gatataacct ccataatttc cgagttctag
     7561 ggatttggct aaaggcatca gaccgtaagt cggtcggccg gatgccaaca cgatacgtac
     7621 tcccatctgc tgaactttca gcaaagcagc caatgtacgt ttactaattt cttttgcatc
     7681 attgagaagc gttccgtcta catcaagaac taataattta tacttcatgg acacacgatt
     7741 ttgatttaga ttacaaaggt aggaaattga gtgaacgact gaaagcggaa agagataaaa
     7801 attactttaa tttcactctt tcagatgcat ttccaaataa tcacgaagga ttcgggcatg
     7861 attataaacc ggttctttgg atgcataaag caaagtgatc accggatgag gtttgataag
     7921 agtcagaaaa tcggcaacag cttgagaagc ttccagttcc ttctgataca ttacgacaaa
     7981 atcattccag tgacccggaa tatcttcatg aaaccatctg cgcagtgctg cggaaggcgt
     8041 tatatctttt gcccagtaat catatttcaa ccattctttt ttgattccac gtggccagag
     8101 tttatctacc agcacccgat atccgtcggt ctctgaaaag tcttcgtaca ctcgctttat
     8161 cctaacttgc accatttccg tttatattta gttatcataa gaataaaccg ataaaacgga
     8221 aaattgttta tcgaaaaagc caaaatcaac ctaaggattc ctgcgttttt ttaaattcgt
     8281 aaggagtcat accagtcttt ttcttgaaca tactgtacag aataggcgta ctattaaatc
     8341 cggcttcatc agctatcgca cgaatggtat aattgggatg ttgcttcaat aactgaatcg
     8401 catagttaat acgaagttca ttaatatacc cgttgaaatt agttccggtg ttttccttga
     8461 tcatccgggc gaaacgcgca ttattcaaat gtacaatctg agccagatcc tctctcgaca
     8521 attccggaga cagatataac tgatcctgaa caacaatacg attcagttct ttgaaaattt
     8581 tcttattctc atcctcttcc tccctactct ccactacttc atccggagat aaatcgtctt
     8641 tttcggaaaa gccagtttcc ggttccaagt ccaatggaac agctatcgga tcttccgcat
     8701 ctccatctat gaataattgt ttgttctcta cttttccagc cagtttctca ttgataaact
     8761 ttgccagcat tttgttttta tatttaacaa taatcatatg acgccaaatc cgccatagca
     8821 caaataaaat gagacaagtg acacatccca aaaaagcaag tgatatgttt ctgattctta
     8881 actgtaaagt ctgttcggca atatattctt cctgctcgtc agctttatga atagcattta
     8941 attccaaagc cgcattctgc ttatccttgc tgttaatacc atcaataata gaaataatag
     9001 actcacgtaa tgctgctact ttttcaaaat ccttcaagcc tttataagct ttcacctctt
     9061 tctgaaggat actaatatac tgcaagttga cagtatcctg ctcttgcatc aatttcttaa
     9121 aatcctgaca ttgatcaacg actttctgat attgtttaga cactagcaga taaggtatcg
     9181 cataggtttt tccatccggt gtctgtgaat tctctgttga caaatattgt tgataatatt
     9241 tttccgcctg atcatacttt ccttccagat agcagatata cgacattttt gcatacaagt
     9301 aagtatattg cagatcaaga aagccttttg ttttttccgg taatttagct atatctttaa
     9361 gtagcttttc gcgcttcaac ccaacctcca atgcttcttt actacgggaa tcattgagca
     9421 gataatccat tttcatccca taaaagtatg aaagcatagc catttccaat ttggaacttg
     9481 taccttgaag caatttgata gctttgtcaa aatagtcata tgcctcctct ttgaaagaca
     9541 attgccattt attttcacca atgcaaaaca acagcttact ttcagcccct ttatcctttt
     9601 ctttttgtgc tagcttgata ccatcaagag catacctcat actctcttta tggtcactca
     9661 taagcactgc taattctgcc aggtcgacag tcatggtcaa caagtgctta ggatctttct
     9721 gagaaacgga atccagcaaa taagactttt tggcatacaa aaaagccagt ttagtcatat
     9781 acatattacg ataaaccctg ctgcgtaatt catgtataat acgcagaggg atagtcttct
     9841 tactttcagc tccatccaac aaacttaaag cccgttcagg ttctgccata taaattcgac
     9901 ttatatactc actggtatat agcgaatcat tctctatagt tttgtcggcg aaaaggagct
     9961 ggttaaacac ctgtctctta tacacatctg acgctgccga cgacttaata ggtgtaga
//
