LOCUS       c00332_gnlPro..         4902 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HBJAAMNO_332.
ACCESSION   c00332_gnlPro..
VERSION     c00332_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 05:38:25
            Original ID  :: gnl|Prokka|HBJAAMNO_332
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4902
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4902
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[761:4891]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      762..4891
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4902
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4902
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(19..762)
                     /locus_tag="ctg332_1"
                     /transl_table=11
                     /translation="MSEENKIGTYQFVAEPFHVDFNGRLTMGVLGNHLLNCAGFHASDR
                     GFGIATLNEDNYTWVLSRLAIELDEMPYQYEKFSVQTWVENVYRLFTDRNFAVIDKDGK
                     KIGYARSVWAMINLNTRKPADLLALHGGSIVDYICDEPCPIEKPSRIKVTSNQPVATLT
                     AKYSDIDINGHVNSIRYIEHILDLFPIELYQTKRIRRFEMAYVAESYFGDELSFFCDEA
                     NENEFHVEVKKNGSEVVCRSKVIFE"
     CDS             complement(762..1325)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_2"
                     /sec_met_domain="ALS_ss_C (E-value: 2.2e-20, bitscore:
                     60.9, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDKTLYTIIVHSENIAGLLNQVTAVFTRRQINIESLNVSASSIK
                     GVHKYTITAWTDKDTIEKVVKQIEKKIDVIQAHYFTEDEIYFHEIALYKVSTPAFQETP
                     EASKVIRRYNARIVEVNPVFSIVEKNGMSEEITSLYEELRALKCVLQFVRSGRVAITTS
                     CFERVNEFLDGQEAKYKQSKKEQE"
     CDS             complement(1344..3041)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-48, bitscore:
                     152.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDLITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNT
                     LNHILVRHEQGAAHAAQGYARVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAG
                     QVGTGFLGTDAFQEVDLVGITQPIAKWSYQIRRAEDVAWAIARAFYIASSGRPGPVVLD
                     FAKNAQVEKTKYEPTKQEFIRSYVPVPDTDEESVKAAAELINNAERPLVLVGQGVELGS
                     AQEELRTFIEKADMPAGCTLLGLSALPTDHPLNKGMLGMHGNLGPNINTNKCDVLIAVG
                     MRFDDRVTGNLATYAKQAKVIHFDIDPAEVNKNVKVDIAVLGDCKKTLAAVTGLLKKNR
                     HTEWVDSFKEYEAVEEEKVIRPELHPATDSLSMGEVVRAVSEATRHEAILVTDVGQNQM
                     ISARYFKYTKERSIVTSGGLGTMGFGLPAAIGATFGRPDRTVCVFMGDGGLQMNIQELG
                     TIMEQKAPVKIICLNNNYLGNVRQWQAMFFNRRYSFTPMLNPDYMKIASAYDIPSKRVF
                     SREELKAAIDEMLSTDGPFLLEACVVEEGNVLPMTPPGGSVNQMLLEC"
     CDS             complement(3089..4891)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg332_4"
                     /sec_met_domain="ILVD_EDD (E-value: 1.5e-218, bitscore:
                     714.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQLRSSFSTQGRRMAGARALWAANGMKKNQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQLVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADDSVSDQEVANIEQNACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRTKLFEDAAKLIVENAMKYYEEGDESVLPRSIATRQAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGVDFKMDDIDMLSRKTPCLCKVAPNTQKYHIQDVNRAGGIIAILAELAKGG
                     LIDTSVLRVDGMSLAEAIDQYSITSPNVTEKAMSKYSSAAGNRFNLVLGSQGAYYQELD
                     KDRANGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQEA
                     ACEGILGGRVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIVDGDIIEIDIPARTINVRLTDEELAARPMTPVTRDRY
                     VPKSLKAYASMVSSADKGAVRLID"
ORIGIN
        1 taagagacag actctatatt attcaaatat cactttggaa cggcatacta cctcgctgcc
       61 gtttttcttc acctctacat gaaactcgtt ttcattcgcc tcatcacaga agaaagagag
      121 ttcatctccg aaataacttt cagccacata cgccatttca aaccggcgga tacgtttcgt
      181 ctgatacagt tctatcggaa acaagtcaag tatgtgctcg atataacgaa tactgtttac
      241 gtgtccgtta atatcgatat cactgtattt tgccgtcagc gtcgcaacag gctgattgct
      301 tgtcaccttg atacgcgaag gcttttctat cgggcagggt tcatcgcata tataatcgac
      361 gatgcttcct ccatgcaatg ccaacagatc ggcaggctta cgggtattca gattgatcat
      421 cgcccatacg gaacgggcat agccgatctt ctttccatcc ttgtcaatga cggcaaagtt
      481 acggtcggta aagagacgat agacattctc cacccatgtc tgaaccgaga acttctcgta
      541 ctggtaaggc atctcatcca gctcgatagc caggcgggaa agcacccatg tgtaattgtc
      601 ctcgttcagc gtagcaatac caaatccacg gtcgctggca tgaaaacctg cgcaattcag
      661 cagatgattt cccagcacgc ccatggtcag gcggccgtta aaatctacgt gaaacggctc
      721 tgccacaaac tgataagtcc ctattttatt ttcttcactc attactcctg ttccttttta
      781 ctttgcttat acttcgcttc ctgtccgtcc aggaactcat tcacacgttc gaaacagctg
      841 gtagtaatag ccacacggcc cgaacggaca aactgcagca cacatttcaa agcccgaagt
      901 tcttcgtaaa gggaagtaat ctcttcactc atgccgttct tctcgacgat agagaatacc
      961 ggattcacct ctacaatgcg ggcattatat ctgcggatca ctttagatgc ttccggagtc
     1021 tcctgaaaag caggagtaga taccttatat aaggctatct catggaaata aatctcgtct
     1081 tccgtaaaat agtgcgcctg aatcacatca atcttctttt cgatctgctt caccaccttt
     1141 tcgatagtgt ccttatcagt ccacgctgta atcgtatatt tatgtactcc tttaatggaa
     1201 gaagcagaaa cgttcaaact ctcgatgttt atttgccgac gggtaaatac agcggtcacc
     1261 tgattcagca atccggctat attttcagaa tgaactataa tcgtatataa tgtcttatca
     1321 ctcataactt tctaaattaa ggattaacat tccagcaaca tctgattgac tgaaccgccc
     1381 ggaggggtca tcggcaggac attgccttct tctaccacac aggcttcgag caggaacggc
     1441 ccgtctgtcg aaagcatttc gtcgatagcc gctttcaatt cttcccgtga aaagacacgt
     1501 ttggaaggaa tatcgtaggc ggaagcgatt ttcatgtaat ccggattcag catcggagta
     1561 aatgaataac ggcgattaaa gaacatggcc tgccattggc gcacgttgcc gagataattg
     1621 ttgttcaggc agataatctt caccggagct ttctgttcca tgatcgtacc cagctcctga
     1681 atgttcattt gcaatccgcc gtcacccata aatacgcata ccgtgcggtc gggacggccg
     1741 aaagtagctc cgatagctgc cggaaggcca aaacccatcg tgccgagtcc acccgaagta
     1801 acgatactac gttccttggt atatttaaag tagcgggcag agatcatctg attctgacct
     1861 acatctgtca ccaatatggc ttcgtgacgg gtcgcttcgc ttaccgcacg caccacttcg
     1921 cccatactca gtgaatccgt tgcaggatga agttcgggac gaatgacttt ttcttcctct
     1981 accgcttcat attccttgaa actatcgacc cactcggtgt gccggttctt tttcagcagt
     2041 ccggtcacag cagccagcgt ttttttgcag tcgcccaaaa cggcaatgtc tacctttaca
     2101 ttcttattta cttccgccgg atcaatgtca aaatggatca ctttcgcttg tttggcgtaa
     2161 gtagccagat taccggtcac acggtcgtcg aaacgcatac cgacagcaat cagtacatca
     2221 catttgttag tattgatatt cggtcccaga tttccgtgca tacccagcat tcctttattc
     2281 aacggatggt cggtaggcaa tgcggaaagt ccgagcaagg tacaacctgc gggcatatcc
     2341 gccttttcga taaaggtacg cagttcttcc tgagcgctcc ccagttccac tccctgtcct
     2401 accaagacaa gcgggcgttc ggcgttattg atcagttcgg cggcagcctt taccgattct
     2461 tcgtctgtat cgggaaccgg aacatagctg cggataaact cctgctttgt cggctcgtat
     2521 ttcgtttttt caacctgcgc attcttggca aagtcgagta ccaccggacc gggacggcca
     2581 ctactggcaa tgtagaaagc acgtgctatt gcccaggcta cgtcttcggc acggcgaatc
     2641 tgatagctcc atttagcgat tggctgagtg atacctacga gatcgacttc ctgaaaagcg
     2701 tctgttccaa ggaagcctgt tcccacctgt cctgcaatga caacgatagg cgtactgtct
     2761 atcattgcat ctgcaatacc tgtgatcgta ttggttgctc cggggccgct tgttaccaag
     2821 caaacaccga ctttacccga tacacgggcg tagccttgtg ccgcatgggc agctccctgt
     2881 tcatggcgaa ccaagatatg gttcaatgta ttttgatggt cgtacagggc atcgaacgta
     2941 ggcatgatgg aaccgccggg ataaccgaaa atggtagtca ctccctgatg ttccagagag
     3001 cgcatcattg cctctgcgcc tgttattaag tccttactca tagttcttta atggataatg
     3061 gataattcat aatggataat gaagtggatc agtctattaa tctcactgct cccttatcgg
     3121 cagagcttac catgctggcg tatgctttca ggctcttcgg cacgtaacga tcacgggtga
     3181 cgggagtcat cgggcgggca gccagttctt catctgttaa tcgcacgtta atcgttcggg
     3241 cgggaatgtc gatttcgatg atatctccat ctactatttt tcctatatta cctccggcag
     3301 cggcttcggg agaaacgtgt ccgatactca atccggaagt tccaccactg aaacgtccgt
     3361 cggtaatcaa ggcacattct ttgccgaggt gacgggattt gatataagaa gtcgggtaaa
     3421 gcatttcctg cataccggga ccacccttcg gaccttcgtg cgtgatgacg acaacgtcgc
     3481 cactgacgac tcggcctccg aggatgcctt cacaggctgc ttcttgtgag tcgaatactt
     3541 tggcaggtcc ggtaaacttc cagatgcttt cgtctacacc cgccgttttt actacgcaac
     3601 cgtcctgagc gatatttcct ttcagtaccg ccaggcctcc gtccttgcta taggcgtgct
     3661 ccagatcacg gatacatccg ttcgcgcgat ctttatctaa ttcctgataa taagctccct
     3721 gagaaccaag tacgagattg aatctgtttc ctgccgcact tgaatatttg ctcattgctt
     3781 tttctgttac gttcgggctg gtaattgaat attgatcgat cgcttccgcc agcgacatgc
     3841 catccacacg gagaacggaa gtatcaatca gaccgccttt tgccaactca gccaggatag
     3901 caatgatgcc acccgcacgg ttaacgtcct gaatatgata tttttgagta ttcggagcga
     3961 ctttacacag gcagggtgtc ttgcgtgaca gcatatcgat gtcgtccatc ttgaaatcga
     4021 ctcctgcctc atgtgccacg gccaacaggt gaagcaccgt attggtagaa ccgcccatcg
     4081 caatatccag cgtcatggca ttgaggaatg cctgacgggt agctatgctg cggggaagta
     4141 cactttcgtc accttcttca taatatttca ttgcattttc cacaatcagt ttggcagcgt
     4201 cttcaaacag tttcgtacga ttttcgtgcg tagccacaat tgtgccgttt cccggaagcg
     4261 ccaagccgat agcttcattc agacagttca tcgagtttgc cgtaaacatt ccggaacaac
     4321 atccgcaggt aggacaggca ttctgttcta tattcgctac ttcctgatcg cttacactgt
     4381 cgtccgctga tttaatcata gcatcgatca agtccagatg ctggccgttc cactctccgg
     4441 cttccattgg tccgccggat acgaatacgg tagggatatt caggcgcatg gcagccatca
     4501 acattcccgg ggtgatctta tcacagttgc tgatacatac cattgcatcc gccttgtgcg
     4561 cattgaccat atattctacg ctgtccgcta tgatatcacg ggaaggaagc gagtaaagca
     4621 ttccgtcatg tcccatagcg ataccgtcat caatagcaat cgtattaaat tccgcagcga
     4681 agcatcccag cttctcaatt tccgccttca ccaactgccc gatttcatgc aggtgcacgt
     4741 gtcccggaac aaattgtgta aacgaattga cgatagcgat aatgggtttt cccatctgat
     4801 ttttcttcat gccgttggct gcccataatg cgcgggctcc cgccatgcga cggccttgtg
     4861 tactaaacga actgcgtaat tgctttttca tttcaatcta tc
//
