LOCUS       gnlProkkaKOAMHLGD_528   2983 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOAMHLGD_528.
ACCESSION   gnlProkkaKOAMHLGD_528
VERSION     gnlProkkaKOAMHLGD_528
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 23:03:04
            Original ID  :: gnl|Prokka|KOAMHLGD_528
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2983
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..2983
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[707:2015]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      708..2015
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..2983
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..2983
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             2..430
                     /locus_tag="ctg528_1"
                     /transl_table=11
                     /translation="MFYKMDNLCKLGYVAAGYLLKDTNYRPEEIGIILANASASLDTDC
                     RHQAIINKEGDKAASPAVFVYTLPNVVLGEICIRHKIQGENTFFVCQQSDTASLEDYAR
                     IVMAKSKLRTCIIGWCELLDGHYQAEFKQLNNISTIYE"
     CDS             423..704
                     /NRPS_PKS="Domain: PP-binding (22-68). E-value: 5.7e-11.
                     Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg528_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg528_2"
                     /sec_met_domain="PP-binding (E-value: 4.1e-12, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLDQTKRELMDEVKGKLIEELNLEEITPEDIDDEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVCTLTDYIIANRKA"
     aSDomain        489..626
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_2_PP-binding.1"
                     /evalue="5.70E-11"
                     /label="ctg528_2_PP-binding.1"
                     /locus_tag="ctg528_2"
                     /protein_end="68"
                     /protein_start="22"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     E"
     CDS             708..2015
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (152-423). E-value:
                     1.2e-38. Score: 125.0. Matches aSDomain:
                     nrpspksdomains_ctg528_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 253.5; E-value:
                     6.3e-77)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg528_3"
                     /sec_met_domain="APE_KS2 (E-value: 9.7e-114, bitscore:
                     368.4, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALQQGKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLLSLPPQRTVSRTALLGMIAAKEAMEDAGLNLRISSNQPKNQLPNQ
                     SVTSQKDQQPLRIGFISATSVGGMDLSERFYESFKKNPKQGRLREVISHDCGASTELIA
                     SYLGINDFITTISTACSSAANAIMLGARLIKHGQLNAVIVGGTDALCRFTLNGFNSLMI
                     LDKIHCRPFDRSRSGLNLGEGAGYLVLQSESSLQRVPYCELSGYANTNEAYHQTGSSPE
                     GDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKA
                     FIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEPMPETELLSETGVKSETGLIPETSF
                     QEGVPIRHVLSNSFGFGGNDSSLLFSATNFPKRTNL"
     aSDomain        1164..1976
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg528_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="1.20E-38"
                     /label="ctg528_3_PKS_KS.1"
                     /locus_tag="ctg528_3"
                     /protein_end="423"
                     /protein_start="152"
                     /score="125.0"
                     /tool="antismash"
                     /translation="HDCGASTELIASYLGINDFITTISTACSSAANAIMLGARLIKHGQ
                     LNAVIVGGTDALCRFTLNGFNSLMILDKIHCRPFDRSRSGLNLGEGAGYLVLQSESSLQ
                     RVPYCELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISPEDIDYINVHGTGTPG
                     NDASEGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTE
                     PMPETELLSETGVKSETGLIPETSFQEGVPIRHVLSNSFGFGGNDSSLL"
     CDS             2028..2981
                     /locus_tag="ctg528_4"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQENNPKVNDSLDVAANRPFLQACEPD
                     YKDIIANATLRRRMSRIVKMGVACGLECMGELSPEKIGGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQGIQWLVTGKNKKQSLQGDYHEQITGYKKSTINEGK
                     STNQRSIINGESIINEKDIIIKEIMMNESNSIYEELE"
ORIGIN
        1 gaagttctac aagatggata atctttgtaa gcttggatat gtagctgccg gatatttatt
       61 gaaagatacc aactaccgtc cagaagagat tggaatcatt ctagccaatg cttccgcctc
      121 tttggatacg gactgcagac atcaagctat catcaataaa gaaggagaca aagccgccag
      181 tcctgccgta tttgtctaca ctctccccaa tgtagtattg ggagaaatct gtatacgaca
      241 caaaattcag ggagaaaata cattctttgt ctgtcagcaa tccgacactg cttccttaga
      301 ggattacgca agaattgtga tggcgaaaag taagttacgc acatgcatca taggctggtg
      361 cgaactactg gacggacatt atcaagcaga atttaaacaa cttaataata tatcaacgat
      421 ttatgaataa tttagatcaa accaaaagag aactgatgga cgaagtgaaa ggtaaactaa
      481 tcgaagagtt gaaccttgaa gaaatcactc cggaagatat tgacgatgaa gcccctctgt
      541 ttggcgacga aggtcttggc cttgactcca ttgacgcact cgaaatcatc ctgattttgg
      601 aacgtgaata tggcattaaa atagagaatc ctagtgaagg aaaacaaatc ttctactcgg
      661 tatgtacact gactgactac atcattgcta atcggaaagc ttaacttatg aagatttacg
      721 tcaccggatt gggagttgtt tcgggcatcg gcatcggagt ttccgaaaat atagaggcac
      781 tacaacaagg aaagcatggt atcggaaagg taactctttt cccgactgct ctcgatgtac
      841 ccgtatctga agtgaaacgt agcaatgaag aacttaaaca actattatct ttacctccgc
      901 agcgtacagt atcacgcaca gcattgctag gcatgatagc cgccaaagaa gcgatggaag
      961 atgcaggact aaacttgcgt atatcatcca atcagccaaa aaatcaatta ccaaatcagt
     1021 cagtaacctc gcaaaaagac cagcaaccgt tacgtattgg ttttatttcc gccacctctg
     1081 tcggcggtat ggatttaagc gagcgtttct atgaatcttt caagaaaaac ccgaaacagg
     1141 gacgattgcg ggaagtgatt tcacacgact gcggagccag taccgaatta atagcttcgt
     1201 atttaggtat caatgatttt ataaccacca tcagtacagc ctgttcatcg gcagccaatg
     1261 ctattatgtt gggagcgaga ctgattaaac atggacaact gaatgctgtt atcgtcggag
     1321 gtacggatgc actttgccgg tttacgctca atgggttcaa ctctctcatg attttggaca
     1381 aaatacattg tcgtcctttt gaccgttcac gttccggatt aaatttggga gaaggcgcgg
     1441 gttatttagt gcttcaatca gaaagttcac tccaaagagt tccttactgt gaactaagcg
     1501 gttatgctaa tacaaatgaa gcttatcatc aaacaggaag ttctcccgaa ggagatggcg
     1561 cctttctatc aatgagtgaa gccatcgctt ccagtggcat ttctcctgaa gatattgatt
     1621 atatcaacgt acatgggaca ggtactcccg gtaatgacgc atcggaagga atggcactac
     1681 gaagaatctt cggagaacat gttccaccgt ttagttcggt aaaagctttt atcggacaca
     1741 ctttaggagc ttccgaagga attgaagctg tttattccgt tctttccata gataaaggca
     1801 tgatttatcc gaatctgaat ttcacggagc ctatgccgga aacagaactg ttgtcagaaa
     1861 caggagtaaa atcagaaaca ggattgatac cggaaacatc tttccaggaa ggagtgccga
     1921 tccgccatgt attatccaat tctttcggct tcggaggaaa cgactcgtcg ctcctctttt
     1981 ccgcaacgaa ttttcccaaa cgaacgaacc tttaagtttt tgagcctatg cagccagttt
     2041 atattcaacg catcgcttct atccatccac aaggaaatca ttcacaagaa aataatccga
     2101 aagtaaatga ttcgctcgat gttgcagcaa accgtccttt tcttcaggct tgtgaacccg
     2161 attataagga tattattgcc aatgcaactt tgcgcaggcg catgagccgt attgtgaaaa
     2221 tgggagtggc ttgcggattg gaatgtatgg gcgaactatc tcccgagaag atagggggaa
     2281 ttatcacagc cacagggctg ggctgcctgg ttgatacgga aaagtttctg aacaacctgt
     2341 tagataatga agagcggatg ctgaatccta ctccttttat tcagtcgaca ttcaatacaa
     2401 ttggtgcaca aatagcactg attcatcaaa tacatgccta taacatgact tatgttcacc
     2461 ggggactaag ttttgaaagc gctttgctgg atgccatgat gaaaatagaa gaaggaagcg
     2521 agaatatact ggtgggagcc atggacgaaa tgacagaaac cagttacatc attcagcaac
     2581 gcttgggact gctgaaagga atagaagccg gagaaggcgc tcaattcttc ctattaagcc
     2641 gggaagccgg agagcatccg ttagcagaaa tacgaggact tgaaactttc acgggacaac
     2701 atacgacaga agaaatcagt tcccgaatta ttcgtttttt acaacgaaac ggattagagt
     2761 gtcagggtat tcaatggtta gttaccggaa agaacaaaaa acaatccctt caaggtgatt
     2821 accacgagca aatcactggt tataagaaga gtactataaa tgaagggaaa agtacgaatc
     2881 agagaagtat tataaacggg gagagtatca taaatgaaaa agatataata attaaggaga
     2941 ttatgatgaa tgaaagcaat tctatctatg aagagcttga aac
//
