LOCUS       gnlProkkaODKKLADI_39   22445 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODKKLADI_39.
ACCESSION   gnlProkkaODKKLADI_39
VERSION     gnlProkkaODKKLADI_39
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 22:56:39
            Original ID  :: gnl|Prokka|ODKKLADI_39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22445
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22445
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[2:2445]"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3..2445
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(APE_KS1 or APE_KS2)"
                     /neighbourhood="20000"
                     /product="arylpolyene"
                     /protocluster_number="1"
     cand_cluster    1..22445
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(APE_KS1 or APE_KS2)"
                     /kind="single"
                     /product="arylpolyene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22445
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="arylpolyene"
                     /region_number="1"
                     /rules="(APE_KS1 or APE_KS2)"
                     /tool="antismash"
     CDS             3..860
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_1"
                     /sec_met_domain="APE_KS2 (E-value: 1.6e-21, bitscore: 67.2,
                     seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNSLKPYFGHTLGASGIIETILCIEQLKEGIYYGTLGYETLGVP
                     MPITVYSTHQPMPMKCCIKTASGFGGCNAALVLSLPDAHLKQKTDSPASCKAAVESANI
                     VTIKPGVLENQGTATVNSPETDFAPFIREAYKHLGENNMKFYKMDNLCKLGYVAAGYLL
                     KDTNYRPKEIGIILANASSSLDTDCKHQAIINKEGDKAASPAVFVYTLPNVVLGEICIR
                     HKIQGENTFFVCQQSNVASLEDYARIVMAKGKLRTCIIGWCELLDGHYQAEFKQLNNIS
                     TIYE"
     CDS             853..1134
                     /NRPS_PKS="Domain: PP-binding (22-68). E-value: 5.7e-11.
                     Score: 34.7. Matches aSDomain:
                     nrpspksdomains_ctg39_2_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_2"
                     /sec_met_domain="PP-binding (E-value: 2.3e-11, bitscore:
                     34.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLDQTKRELMDEVKGKLIEELNLEEITPEDIDDEAPLFGDEGL
                     GLDSIDALEIILILEREYGIKIENPSEGKQIFYSVCTLTDYIIANRKA"
     aSDomain        919..1056
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_2_PP-binding.1"
                     /evalue="5.70E-11"
                     /label="ctg39_2_PP-binding.1"
                     /locus_tag="ctg39_2"
                     /protein_end="68"
                     /protein_start="22"
                     /score="34.7"
                     /tool="antismash"
                     /translation="LNLEEITPEDIDDEAPLFGDEGLGLDSIDALEIILILEREYGIKI
                     E"
     CDS             1138..2445
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (156-423). E-value:
                     8.1e-39. Score: 125.5. Matches aSDomain:
                     nrpspksdomains_ctg39_3_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     arylpolyene: APE_KS2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 251.8; E-value:
                     2.1e-76)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_3"
                     /sec_met_domain="APE_KS2 (E-value: 9.1e-114, bitscore:
                     370.9, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIYVTGLGVVSGIGIGVSENIEALQQGKHGIGKVTLFPTALDVP
                     VSEVKRSNEELKQLLSLPPQRTVSRTALLGMIAAKEAMEDAGLNLRISSNQPKNQLLNQ
                     PVTSQKDQQPLRIGFISATSVGGMDLSERFYESFKKNPKQGRLREVISHDCGASTELIA
                     SYLGINDFITTISTACSSAANAIMLGARLIKHGQLDAAIVGGTDALCRFTLNGFNSLMI
                     LDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSPQRVPYCELSGYANTNEAYHQTGSSPE
                     GDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDASEGMALRRIFGEHVPPFSSVKA
                     FIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEAMPETELMSETGVKSETGLIPETSF
                     QEGLPIRHVLSNSFGFGGNDSSLLFSATNFPKRTNL"
     aSDomain        1606..2406
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_3_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="8.10E-39"
                     /label="ctg39_3_PKS_KS.1"
                     /locus_tag="ctg39_3"
                     /protein_end="423"
                     /protein_start="156"
                     /score="125.5"
                     /tool="antismash"
                     /translation="ASTELIASYLGINDFITTISTACSSAANAIMLGARLIKHGQLDAA
                     IVGGTDALCRFTLNGFNSLMILDKIHCRPFDRSRTGLNLGEGAGYLVLQSESSPQRVPY
                     CELSGYANTNEAYHQTGSSPEGDGAFLSMSEAIASSGISPEDIDYINVHGTGTPGNDAS
                     EGMALRRIFGEHVPPFSSVKAFIGHTLGASEGIEAVYSVLSIDKGMIYPNLNFTEAMPE
                     TELMSETGVKSETGLIPETSFQEGLPIRHVLSNSFGFGGNDSSLL"
     CDS             2458..3483
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="MQPVYIQRIASIHPQGNHSQGNNPKVNDSPDVSANRPFLQACEPD
                     YKDIIANATLRRRMSRIVKMGVACGLECMGELSPEKIGGIITATGLGCLVDTEKFLNNL
                     LDNEERMLNPTPFIQSTFNTIGAQIALIHQIHAYNMTYVHRGLSFESALLDAMMKIEEG
                     SENILVGAMDEMTETSYIIQQRLGLLKGIEAGEGAQFFLLSREAGEHPLAEIRGLETFT
                     GQHTTEEISSRIIRFLQRNGLECQDIQWLVTGKNKKQSLQGDYHEQITNSIYEELETNL
                     FPESIHLSFKDECGEYPTASSYAVWKAVKTSINCTTPTNILIYNHHHSINHSLILIRKS
                     V"
     CDS             3480..4160
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235:polysaccharide deacetylase (Score: 127.2;
                     E-value: 1.3e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_5"
                     /transl_table=11
                     /translation="MMIVCLLLCLFLILSFLVYASYSIQSGIYLRSFCKKRTTEKVVAL
                     TFDDGPDPIQTPKVLKVLKEYQATACFFCIGHKIKGNEALLKSMVTEGHLIGNHSYSHS
                     GLFPLYGLSKMKKDLQTCQCELERVTSQPVTLFRPPFGVTNPTIAKAVRQLGYTSIGWS
                     IRTLDTQQSAPDKILARIRKRLKPGAIILLHDRMPGSDQLVKQILDLLKEQGYTVVRPD
                     KLLA"
     CDS             4238..4807
                     /locus_tag="ctg39_6"
                     /transl_table=11
                     /translation="MKKMVQKTEFENRLAKEAQTVKSIESDFTQVKYLDVFDEKVTSKG
                     KFYYQKSNKICMEYFRPMNYLIVINGSKLKIVSDGKKSIMNLSSNKMMAQMQDMLTACM
                     IGDLSKMSSNYQLEYFEDARYYLVKIKPTNKAVQAYIAGIEIYLDKKDMSVHKLRLSET
                     ATNYTEYEFYNKKFNSLKNETKFAIR"
     CDS             4782..5342
                     /locus_tag="ctg39_7"
                     /transl_table=11
                     /translation="MRRSLRFVSLTVLLFLGIQVQTSCSPRISGEGSTVPPVIELTQGE
                     ESQKYNIQLDFMKHHMSGMLIVRRMPDNEIRIVASTYFGLSLFDFSLHDDQFNVNSCIE
                     PMKKEKVLKLLEMDFRRLFLNGKDVRVKATKDNATQKRTSGKGFGKSVVYITDDTPGDP
                     AQIKIKHPWIRLTIRLDKLSKEI"
     CDS             5346..5825
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MLLDNFYTILSSESSDSTTWTIQIELNPDHTVYQGHFPEHPVVPG
                     VCLLQLIKECAENIRQQKLQITQVSSCKFLSAINPIETPRIAIVLSLKETEEGKLQLQA
                     EGTVKEKTVNKSIVKEDIAKEEIVKENTGKESIIKEENIKDECFIKLKAALTPKA"
     CDS             5822..7012
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 84; E-value: 2.2e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-29, bitscore:
                     93.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEQISTAYWHEKLKQLGIIVIIPSYNNGKTLAEVIASVRFYAPE
                     ILVVNDGSTDETPEILNQEANLHIITHPVNQGKGVALKHGLSFAKKQGFRYAITIDSDG
                     QHFASDIPVLIEAIEKEPDTLLVGSRNLASDNMPGKNTFANKFSNFWFTLETGIKLQDT
                     QSGYRLYPIQRMNVDKWYYTAKYEFELEALVFAAWGGNPVKNIPVHVYYPPQEERVSHF
                     RPFRDFTRISILNTVLVLVTFLWIVPRNFFRKLTWKNCKQFFSNHITHSPESNLRITAA
                     IMFGVFMGIVPAWGYQMLITLFLAHLFRLNKVIAIVAANISIPPMIPFLLYGSYVTGCK
                     VLGEPVNLHLNELSFENVKSVIEQYLIGSVIFAVVCSILAGTIAFILLTACRKKKI"
     CDS             7009..10875
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     45.2; E-value: 6.4e-14)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_10"
                     /transl_table=11
                     /translation="MTQFFIGLYDYFERHKILFYLSLISCVLLMGFFALQVRFEENITQ
                     FFPDTKDSQNTIKVFDNLKIKDKIIIMLSSADTCHQVEPDSLIEAAGQLQQTLTEKAGG
                     TLIKGIFAQVDQSLIGGATDFVYEHLPLFLTDTDYQRFDSLLTEKGIQATMQKNYTNLL
                     SPAGIALRSYILRDPLGLGSEALKHLQDFQLEANYEIYDEHIFSKDGSTLLMFITPVFS
                     TGSTGKNDELIKILEEELQHVQGESPTIRAEYFGGPSVGVYNARQIKKDTILTSSLALL
                     IIIVFISLVFKRKRSIPLIITPVLFGGLFALFLIFFIKGSISAIAVGAGSAVMGIALSY
                     SIHMLAHQNHVSTVQQLIKEIAYPLTVGSFTTIGAFMGLIFTSSDLLRDFGLFASLALV
                     GTTLFCLIYLPHFLKGQADVKQGRVLRIIEKINAYSYEKNKWLVGGILLITIICLFTSQ
                     KVGFNNDMMSLNYEPQHLKQSEEKLMQLFDSDEKTVLFVSVGKDMNQATETYAITNQKL
                     STLKDQGLIKDYASASQFLISPQEQQLRLKRWKDYWTDEKQQQIRKQLETAATEYRFRP
                     GSFDPFYQWLNQPFGEYHYTAQEDDLSGKLLNEWQTSADSITMLISQIRISDQNKETVY
                     QNFSKTQDVVIFDRSYFANKWVSAINDDFYLILYISSFLIFFALWFSYGRIELTLMSFL
                     PMLVSWVIILGLMGILGIEFNIINIILSTFIFGIGDDFSIFIMDGLQNKYRTGQKVLNS
                     HKTAIFFSAFTTVVGMGALVFAKHPALQSISLISILGMIAVVLVAYTIQPLIFRFFIAG
                     PASKGLPPYTLIGLIRTVLLFLLFFIGCIFLRVLIAVLYLVPVRKSSKQRLVCRLIQIT
                     CKGILLLATAVKKEHINKANERFQHPAIIIANHQSFIDILVLLSLSSKILMVTNHWVWH
                     SPFFGAIIRYVDFYYIGEGYEQYMERMRKKVKEGYSIAIFPEGTRTYNGKMKRFHKGAF
                     YLAETLQLDILPILLYGNNKIIAKAQPFNIRKGIIYTEILPRIPADDLSFGTTYQERTK
                     RISAYMKEGYAHICREKNTTDNPAFYEALIQNYIYKGPVVEWYIRIKVKMERNYRLFNR
                     LIPAQGQITDIGCGFGPLCYMLSLLSEDREILGIDYDEDKIALAQHGWLRNEYLQFRHG
                     NALEYPLPESDVFILNDMLHYMSYEHQRTLLLKCADRLRSQGMIIIRDGNSANTSKHRL
                     TRFTELLSTRIFNFNRTTGELYFTTETQLREIAVTCGMNVEIIPNDKYTSNTIYIFRKP
                     NEHE"
     CDS             10868..12358
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 160.4; E-value: 1.4e-48)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_11"
                     /sec_met_domain="DAO (E-value: 1.3e-09, bitscore: 28.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKYDIIIIGSGLGGLECGAILSKEGFNVCVVEKNTQFGGCFQTY
                     RRKGHLFDTGIHYVGSLDEGQVMNQYFRYFGIMDKLKLKRLDDEAFDTIYYKGKTYDYA
                     MGYPQFIETICRSFPHEKENLKRYAEQLQTVGNLISVDHLKQGTLALEGMKYFCTSAAG
                     LIADITPDPTLQNVLAGSALLYGGLKDVSTFYEHAMINHSYIEGAYRFVDGSMQVSLGL
                     INVIRANGGTVLNNSEATRIIVENEKVQGVIINGKERLESDYVISNMHPQRTLEILDKN
                     RSIKNAYISRIRSLENTYGIFTLYLVMKKKSTPYQNRNLYLHGDHKVWYDKQLYPGRTT
                     NCMISMQASSEDSQYASVISILTPMYMDELSAWKDTTPEHRGESYRSFKQEKTEQLLRF
                     IRSHGIDFSDNIEEIHTTTPLSYRDYTGTVDGSAYGIIKDYKCPQIGFVSTRSRLGNLF
                     LTGQNLNVHGALGVTLTSMLTCAEFVGQEYLAKKVGNA"
     CDS             12351..14087
                     /locus_tag="ctg39_12"
                     /transl_table=11
                     /translation="MHKTIKKIFKYTSCVLLSLLVILIAGVCYLYFSADMRTPKHEPSI
                     IMTKVSHAGTTTMVPAEVLYNDTLDLRYYDGNFLRHSESGLWELFVKGDAFQRGEAIGK
                     LSSDLLHYQEKVFVDQIREIVPSDSYLKFLRFFIVLFNRHLGENVLEEYRNEIYGISLS
                     CTHEYDFIGTPYERQLNYHSAHDLGHAMQDYMLVGCSSFATWGTQSADSSLLIGRNFDF
                     YVGDAFAENKQVAFYTPDQGYKFASVGWPGMIGVLSGMNETGLTVTINAAKSAVPTGSA
                     TPISILTREILQYASTIDEAFAIAKKRKTFVSESILIGSAKDGKAAIIEKSPEKTVLFK
                     GKESDRLISTNHYQSEEFSKDERNMENIRTSDSPYRFARLEELINENMPIDASKAASIL
                     RNHKGLQDADLGLANEMAINQFIAHHSVIFQPEKRLMWVSTSPWQCGKYVAYDLNKIFN
                     DTINLQHEIYSSNLTIPADEFTETPEFQHLLTYKKLTPLLLKKIRKKEKIEEHVLKTYE
                     ASNPSLYYVYEVMGDYYEAMQQPQQAIAYWQKALKKPIPKLQEKERIQQKIQKQSKDGK
                     ES"
     CDS             14071..15366
                     /NRPS_PKS="Domain: AMP-binding (56-290). E-value: 7.2e-14.
                     Score: 43.0. Matches aSDomain:
                     nrpspksdomains_ctg39_13_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_13"
                     /sec_met_domain="AMP-binding (E-value: 8e-13, bitscore:
                     38.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNPEIQFRSPEEIKCYQEEKLAQTLTYLQAHSKFYQRMFEEHH
                     IDINQIKKIEDLQQIPVTTKTDLQLHNDDFICVDKEQIIDYVTTSGTLGDPVTFVLTSE
                     DLDRLSYNEYLSFTTTGCSKKDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVGNGIP
                     ELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHIDHNACSMQKCICIGEALRNQEFQLN
                     TLGQKIHDKWSALQLYSTYASTEMQSSFTECSEFHGGHLQPELIIVEFLDDNNRPVAEG
                     EAGEVTITTLGVEGMPLLRFKTGDICYHHTEPCACGRNTIRLSSILGRKGQMIKYKGTT
                     LYPPALFDILDNIPSVKNYIIEVYTNELGTDEILIRIGSENRSEGFAKEIKDLFRSKVR
                     VAPSINFESAEYIAKIQMPPMSRKTIKFIDLR"
     aSDomain        14239..14940
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg39_13_AMP-binding.1"
                     /evalue="7.20E-14"
                     /label="ctg39_13_AMP-binding.1"
                     /locus_tag="ctg39_13"
                     /protein_end="290"
                     /protein_start="56"
                     /score="43.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LQQIPVTTKTDLQLHNDDFICVDKEQIIDYVTTSGTLGDPVTFVL
                     TSEDLDRLSYNEYLSFTTTGCSKKDILQLMTTIDRRFMAGLAYYMGARELGMGVIRVGN
                     GIPELQWDTIRRIHPTCGMVVPSFLIKLIEFAEKNHIDHNACSMQKCICIGEALRNQEF
                     QLNTLGQKIHDKWSALQLYSTYASTEMQSSFTECSEFHGGHLQPELIIVEFLDDNNRPV
                     AEGEAGEVTITT"
     CDS             15493..15993
                     /locus_tag="ctg39_14"
                     /transl_table=11
                     /translation="MKDIQSIKFYGVDYSQAKVFGADESPIQFKDAFRRINELFITEAK
                     KYNVGKQLKKEVTEISLDAVNQVNENINLAELMTTKREYSLSKEQIKAAIEALPIQKTP
                     GVGMVFIAQFLDKSNNRGTYEVVFFNTETKEIIEEWITDGKARGFGLRNYWAGSVYSAL
                     KKL"
     CDS             16013..16753
                     /locus_tag="ctg39_15"
                     /transl_table=11
                     /translation="MRKLLLLLTLLLSISTYVAAQNYTEVVYLKNGSIIKGVIIEQVPN
                     VSLKIKTSDGSLIICQMSDVEKITKEERYTRDYRKEANNRKAARNTLKGYKGFVDFAYI
                     GDVSDYNASKIELSTSHGYQFNNYFFVGGGVALNYYTDADLVAAPIYANFRANFINKRV
                     TPFADVKTGYAVGDIEGAYASIGVGVRFSLKGKKALNLALMYNFQDYEISTDYGYSSGG
                     YYYHSSYDDTWELHGVGVRFGFEF"
     CDS             16763..17425
                     /locus_tag="ctg39_16"
                     /transl_table=11
                     /translation="MSVPFNNKQTINQIRTMKKTITTLLLLSCITAFSFAQSIVMTSGT
                     IDFIKDQQVIQFTFSYDEMLVGKLTESEYVDKKSSEYNAKEEGKGDQWKAAWYGDRKER
                     FEPKFLELFDKYMSEVGITAGTEGAQYRIEINTDFTEPGWNVGVMRQNASVDLSCKVKK
                     IETGEQVASIRIRNASANNFWGTDFTSGYRVQETYAKAGRELAKFFIKKAKLHKIKD"
     CDS             complement(17375..17575)
                     /locus_tag="ctg39_17"
                     /transl_table=11
                     /translation="MQILYLQRICRRYLQRSNYLSASVLRAFCCRWQILLCFFNFIVGK
                     CGSSQLVFYLVQLRLFDKELG"
     CDS             complement(18063..18827)
                     /locus_tag="ctg39_18"
                     /transl_table=11
                     /translation="MSARWKVESPQKGIIHKYASIPRLYQGTQSVSLIEIDPGAGLKVD
                     IAVSGEMKETSRIASEHRGIAAINGSYFDMKRGNSVCFLKVGNQVVDTTTLSECKLRVT
                     GAMHVHKGKIKLIPWSRQIEKEYKGETGIVLASGPLMLKDGQICDWNSCGTNFIRTKHP
                     RSAVATTKEGKILLITVDGRFPEQAEGVNIPELAHLIRILGGEDALNLDGGGSTTLWLS
                     GASDDGVVNYPCDNGRFDHAGERKVPNILYIH"
     CDS             19085..20836
                     /locus_tag="ctg39_19"
                     /transl_table=11
                     /translation="MRTEKEKTIYKMNHKWNYRPITPEQAETSQTLAQELGISPILGQL
                     LVQRGITKAADAKKFFRPQLPDLHDPFLMKDMDIAVERLNRAMGKKERILIYGDYDVDG
                     TTAVALVYKFIQQFYSNLDYYIPDRYNEGYGISKKGVDYAAETGVGLIIVLDCGIKAVE
                     EITYAKEKGIDFIICDHHVPDDILPPAVAILNAKRLDNTYPYTHLSGCGVGFKFMQAFA
                     ISNGIEFHHLIPLLDIVAVSIASDIVPIMGENRILAYHGLKQLNSNPSIGMKAIIDVCG
                     LSEKEITVSDIVFKIGPRINASGRIQNGKEAVDLLTEKDFSVALEKAGQINQYNETRKD
                     LDKSMTEEANNIVANLEGLADRRSIVLYNEEWHKGVIGIVASRLTEVYYRPAVVLTRTD
                     DMATGSARSVSGFDVYKAIEHCRDLLENFGGHTYAAGLSMKVENVDAFTKRFEDYVSRH
                     ILPEQTSAVIEIDAEIDFRDISSKFFNDLKKFNPFGPDNTKPIFCTHHVYDYGTSKVVG
                     RDQEHIKLELVDNKSNNVMNGIAFGQSSHVRYIKTKRSFDICYTIEENTHKRGEVQLQI
                     EDIKPIE"
ORIGIN
        1 ttccggtgaa tagccttaag ccttatttcg ggcatacatt aggagcttcg ggcattattg
       61 aaaccatact ttgcatagag caactaaaag aaggaatata ctacggaact ttaggatatg
      121 agacactagg tgttcccatg cctatcaccg tttatagcac tcatcagccg atgccgatga
      181 aatgttgtat caaaaccgct tctggtttcg gaggctgtaa tgctgcactg gtattatctc
      241 tcccagatgc tcatttgaaa cagaaaaccg attctccggc atcctgtaaa gctgccgtag
      301 aatcagccaa tatagtcacg atcaaaccgg gagtgctaga aaaccaagga acagctacag
      361 tcaattctcc ggagactgac tttgcgccgt ttatccggga agcatacaag catctgggag
      421 aaaacaatat gaagttctac aagatggata acctttgtaa gctgggatat gtagctgccg
      481 gatatttatt gaaagatacc aactaccgac cgaaagagat tggaatcatt ctagccaatg
      541 catcttcctc tttggatacg gactgcaaac atcaagctat catcaataaa gaaggagata
      601 aagccgccag tcctgccgtg tttgtctaca ctctccccaa tgtagtattg ggagaaatct
      661 gtatacgaca caaaattcag ggagaaaata cattctttgt ctgccagcaa tccaacgttg
      721 cttccttaga ggattacgca agaattgtga tggcgaaagg taagttacgc acatgcatca
      781 taggctggtg cgaactactg gacggacatt accaagcaga atttaaacaa cttaataata
      841 tatcaacgat ttatgaataa tttagatcaa accaaaagag aactgatgga cgaagtgaaa
      901 ggtaaactaa tcgaagagtt gaaccttgaa gaaatcactc cggaagatat tgacgatgaa
      961 gcccctctgt ttggcgacga aggtcttggc cttgactcca ttgacgcact cgaaatcatc
     1021 ctgattttgg aacgtgaata tggcattaaa atagagaatc ctagtgaagg aaaacaaatc
     1081 ttctactcgg tatgtacact gactgactac atcattgcta atcggaaagc ttaacttatg
     1141 aagatttacg tcaccggatt gggagttgtt tcgggcatcg gcatcggagt ttccgaaaat
     1201 atagaggcac tacaacaagg gaagcatggc atcggaaagg taactctttt cccgactgct
     1261 ctcgatgtac ccgtatctga agtgaaacgt agcaatgaag aacttaaaca actattatct
     1321 ttacctccgc agcgtacagt atcacgcaca gcattgctag gcatgatagc cgccaaagaa
     1381 gcgatggaag atgcaggact aaacttgcgt atatcatcca atcagccaaa aaatcagtta
     1441 ctgaatcagc cagtaacctc gcaaaaagac cagcaaccgt tacgtattgg ttttatttcc
     1501 gccacttctg tcggcggtat ggacttaagc gagcgtttct atgaatcgtt caagaaaaac
     1561 ccgaaacaag gacgattgcg ggaagtgatt tcacacgact gcggagccag taccgaatta
     1621 atagcttcgt atttaggtat caatgatttt ataaccacca tcagtactgc ctgttcatcg
     1681 gcagccaatg ctattatgtt gggagcgaga ctgataaaac acggacaact ggatgctgct
     1741 atcgtcggag gtacggatgc actttgccgg tttacgctca atgggttcaa ctctctcatg
     1801 attttggaca aaatacattg tcgtcctttt gaccgttcgc gtaccggatt aaatttggga
     1861 gaaggcgcgg gttatttagt gcttcaatca gaaagttcac cccaaagagt tccttactgt
     1921 gaactaagcg gttatgctaa tacaaatgaa gcttatcatc aaacaggaag ttctcccgaa
     1981 ggagatggcg cctttctatc aatgagtgaa gccatcgctt ccagtggcat ttctcctgaa
     2041 gatattgatt atatcaacgt acatgggaca ggtactcccg gtaatgacgc atcggaaggt
     2101 atggcattgc gaagaatctt cggagaacat gttccaccgt ttagttcggt aaaagctttt
     2161 atcggacaca ccttaggagc ttccgaagga attgaagctg tttattccgt tctttccata
     2221 gataaaggca tgatttatcc gaatctgaat ttcacggagg ctatgccgga aacagagctg
     2281 atgtcagaaa caggagtaaa atcagaaaca ggattgatac cggaaacgtc tttccaggaa
     2341 ggattgccga tccgccatgt attatccaat tctttcggct ttgggggaaa cgactcgtcg
     2401 ctcctctttt ccgcaacgaa ttttccaaaa cgaacgaacc tttaagtttt tgagcctatg
     2461 cagccagttt atattcaacg catcgcttct atccatccac aaggaaatca ttcacaagga
     2521 aataatccga aagtaaatga ttcgcccgat gtttcagcaa accgtccttt tcttcaggct
     2581 tgtgaacccg attataagga tattattgcc aatgcaactt tgcgcaggcg catgagccgt
     2641 attgtcaaaa tgggagtagc ttgcggattg gaatgtatgg gcgaactatc tcccgagaag
     2701 atagggggaa ttatcacagc cacagggttg ggctgcctgg ttgatacgga aaagtttctg
     2761 aacaacctgt tagataatga agagcggatg ctgaatccta ctccttttat tcagtcgaca
     2821 ttcaatacaa ttggtgcaca aatagcttta attcatcaaa tacatgccta caacatgact
     2881 tatgttcacc ggggactaag ttttgaaagc gctttgctgg atgccatgat gaaaatagaa
     2941 gaaggaagcg agaacatact ggtgggagct atggacgaaa tgacagaaac cagttacatc
     3001 attcagcaac gcctgggact actgaaagga atagaagccg gagaaggtgc tcaattcttc
     3061 ctattaagcc gggaagccgg agagcatccg ttagcagaaa tacgaggact tgaaactttc
     3121 acgggacaac atacgacaga agaaatcagt tcccgaatta ttcgtttttt acaacgaaac
     3181 ggattagagt gtcaggatat tcaatggtta gttaccggaa agaacaaaaa acaatccctt
     3241 caaggtgatt accacgagca aatcactaac tcaatctatg aagagcttga aaccaacctt
     3301 ttcccggaaa gtattcatct tagttttaag gacgaatgtg gagaatatcc taccgcctca
     3361 tcgtatgccg tatggaaagc agtaaagaca tcaataaact gcactacccc taccaatata
     3421 ttgatttata atcatcacca ctccatcaat cactcattga ttctaattcg gaaaagcgta
     3481 tgatgattgt ttgcctcctt ctatgtttat tcttgatact gtcctttctc gtttatgctt
     3541 cctatagcat tcagtcggga atttatctac gatcgttttg caaaaaacgt actacggaaa
     3601 aagttgtcgc cctgactttt gacgacggtc ccgatcccat tcaaacgccc aaagtattga
     3661 aggtactaaa agaatatcag gcaactgcct gttttttctg tatcggacac aagataaaag
     3721 gaaatgaagc cttattgaaa agtatggtaa cagaaggtca tctaattggg aatcattcat
     3781 atagccattc cggtttattt ccgctatatg gactctctaa aatgaaaaaa gacctgcaaa
     3841 cttgtcagtg tgaactagaa cgagtaactt cgcagccggt tactttgttt cgtccgccat
     3901 tcggtgtcac taatcctacg attgcgaaag ctgtccgaca gttaggatac acctcaatag
     3961 gatggagcat ccgtacatta gatacgcaac agtcagctcc ggacaaaata cttgccagga
     4021 ttcggaaacg tcttaaaccg ggagccatca ttctgttgca cgaccggatg cccggcagcg
     4081 accagttagt gaaacaaata ctggatttac taaaagaaca aggatatacc gttgtccgtc
     4141 cggacaaact attggcataa aataaaaatg tatgagaact ttattactat acttatcgct
     4201 tttcttcttg tctatcgcca ccgtccatgc acagagcatg aaaaagatgg tgcaaaagac
     4261 cgagtttgaa aaccgcctgg caaaggaggc acaaaccgtg aagtccatcg aaagcgattt
     4321 tacccaagtg aaatatctcg atgtattcga cgaaaaggtt acttccaaag ggaagttcta
     4381 ctaccaaaag agcaataaaa tctgtatgga atacttccgc ccaatgaatt atctcatcgt
     4441 gataaacggg agtaagctca aaatcgtatc ggatggcaag aaaagtatta tgaacctaag
     4501 ttcgaacaaa atgatggcac agatgcagga tatgctaact gcgtgtatga taggcgacct
     4561 gtctaagatg tcatccaact accagctaga atattttgaa gacgcacgat attatttggt
     4621 taaaattaag ccgactaaca aagcagtaca agcctatatt gccggtatcg aaatttattt
     4681 ggacaagaaa gatatgtcgg tgcacaaact ccgtctgtcc gaaacagcta caaactacac
     4741 agaatacgaa ttctataata aaaagttcaa ctctctgaag aatgagacga agtttgcgat
     4801 tcgttagcct gacggttctg ttattcttgg gaatacaggt tcaaacgtcc tgctctccac
     4861 gaataagcgg ggaaggcagt actgtgcctc ctgttatcga actgacacaa ggggaagaat
     4921 cacaaaaata caatatccaa ctggatttca tgaaacatca catgagtggt atgctgatag
     4981 tacgccgtat gcctgataac gaaatccgga tcgtggcgtc tacctacttc gggttaagcc
     5041 ttttcgattt ttctctgcat gacgatcaat ttaatgtcaa cagctgcatt gaacccatga
     5101 aaaaagaaaa ggtattgaaa ctgttagaga tggatttcag gcgtttgttc ttaaatggaa
     5161 aagacgtccg tgtgaaagcc accaaagaca atgctaccca aaaaagaacc agtggaaaag
     5221 gctttggaaa atcagtggtc tacattaccg acgacactcc gggtgatccg gcacaaataa
     5281 aaatcaaaca tccgtggata cggttaacga tccgtctgga taaactatct aaagaaattt
     5341 aatatatgct acttgataac ttctatacta tcctttcctc cgagtcatcg gattcaacca
     5401 cctggactat tcagatagag ttgaatcctg accacactgt ttatcaggga cattttcctg
     5461 aacatccggt agttcccgga gtttgtctat tgcaacttat caaggaatgt gcagaaaata
     5521 ttcgtcagca aaagttgcaa ataacacaag tatcttcctg caaatttctt tcggctatca
     5581 atcctataga aacgcctcgg atagcaatcg tactgagtct caaagagaca gaagaaggca
     5641 aactccagtt acaggcggaa ggtactgtaa aggaaaagac tgtaaataaa agcattgtga
     5701 aagaggatat tgcaaaagaa gaaattgtaa aggagaacac aggaaaagaa agcattataa
     5761 aggaagaaaa tataaaagac gaatgtttca ttaaactaaa agctgcactt accccaaaag
     5821 catgaaggag caaataagta cagcctattg gcacgaaaag ttgaaacaat tagggatcat
     5881 cgtcatcatc ccgagttaca acaatggcaa gacactggca gaagtcatag caagtgtacg
     5941 tttttatgca ccggaaatcc ttgttgtcaa tgacggttca acggatgaaa cacctgaaat
     6001 actgaatcag gaagctaatc ttcacatcat cacccaccct gtcaatcaag gaaaaggggt
     6061 agctttgaaa catggactat ctttcgcaaa gaagcaagga ttccgatatg ccatcaccat
     6121 tgattccgac ggacagcatt tcgcttcgga cattcccgta ttgattgaag ccatagaaaa
     6181 ggaaccggac acgttactgg taggctcccg taatctggcc tcggacaata tgccgggaaa
     6241 gaacaccttt gctaataagt tttccaactt ttggttcacc ctcgaaaccg gtatcaaact
     6301 acaagatacg caatccggct accgcctcta ccctatccaa cgaatgaatg tggacaagtg
     6361 gtattacact gccaaatatg agttcgaact ggaagcactt gtttttgcag catggggagg
     6421 caatcccgtt aaaaacattc cggtacacgt ttattatccg ccacaggaag aacgggtttc
     6481 tcatttccgc ccgttccgtg atttcacccg tatcagtatt ctgaatacgg tactggtact
     6541 cgtcactttc ctttggatcg taccacgaaa ctttttccgt aaactgacct ggaagaattg
     6601 caagcagttt ttctccaacc acatcaccca ctcccccgaa tctaacctgc ggattacggc
     6661 agccatcatg ttcggcgtat ttatgggcat cgttccggca tggggatatc aaatgctgat
     6721 tacgttgttt ttggcgcatt tgttccgatt aaacaaagtc atagctattg tagcagccaa
     6781 catcagcatc cctccgatga taccattttt actgtacgga agttatgtaa ccggctgtaa
     6841 agtactggga gaacctgtaa acctgcactt aaacgaactt tcttttgaaa atgtaaaatc
     6901 agtcatagag caatatttaa taggaagtgt tatctttgca gtcgtatgca gcatactggc
     6961 aggaaccatc gcgttcattc tgctcacggc gtgtaggaaa aaaaagatat gacccagttt
     7021 tttatcggac tatatgatta ttttgagagg cacaagattc tgttctattt gtcactcatc
     7081 agttgtgtcc tgttgatggg gttctttgcc ctgcaagtaa gattcgaaga gaacatcaca
     7141 caatttttcc ccgacaccaa agactcccaa aacacaatca aggtattcga caatctcaaa
     7201 atcaaggata agattatcat tatgctatcc tcggcagata cctgtcacca ggtagaacct
     7261 gattccctga tagaagctgc cggacaactg caacaaaccc tgactgaaaa agccggagga
     7321 accctgatta agggaatttt cgcacaggta gaccaaagcc tcatcggagg agccacagac
     7381 tttgtctacg agcatctccc gcttttcctg acagatacgg attatcaacg attcgattcc
     7441 ctattgacag agaagggtat acaagctacc atgcagaaga actataccaa tctcctctct
     7501 cctgccggaa tcgcattaag aagttatatt ctccgggacc cgctcggact gggaagtgaa
     7561 gccctgaaac atctgcagga tttccagttg gaagccaact acgagattta tgacgaacac
     7621 atcttttcca aagacggttc caccttgctt atgttcatta ccccggtatt cagcacaggc
     7681 agtaccggaa agaatgacga actgataaaa atactcgaag aagaactcca acacgtacag
     7741 ggagaatctc ctaccattcg agccgaatat ttcggcggtc cctccgtagg agtctacaac
     7801 gcccgtcaga tcaagaaaga cacgattctg acttcttccc tggcactgct tatcatcata
     7861 gtatttatct cactcgtgtt taaacggaag cgatcgatac cactgattat tactccggta
     7921 ctcttcggag gattgttcgc cctgtttctg attttcttta tcaaaggaag catctcggcc
     7981 attgccgtgg gagccggttc ggcagtgatg ggtattgcgc taagctattc catccacatg
     8041 ttggcacatc agaaccatgt ttccaccgtg caacaactga ttaaagagat agcctatccg
     8101 cttacagtag gtagtttcac cactatcggc gcatttatgg gattgatatt caccagttcc
     8161 gatctgttac gcgatttcgg gttgttcgct tccctggcat tggtgggtac tactcttttt
     8221 tgcctcattt acctgcctca tttcctgaaa ggacaggcag acgtcaaaca gggacgcgta
     8281 ttacgcatca tcgagaaaat aaacgcatat tcttacgaaa agaataaatg gttggtaggc
     8341 ggtattctcc tcattacaat tatctgtttg tttacctcac aaaaggtcgg cttcaacaac
     8401 gacatgatga gcctcaatta tgaacctcaa catctcaaac aatcggaaga gaaattaatg
     8461 cagctcttcg acagcgacga aaagacagtg ctttttgtca gcgtaggcaa agacatgaat
     8521 caggctaccg aaacttatgc aataaccaat cagaagttat cgacactgaa ggatcaggga
     8581 ctgattaaag attatgcttc cgcctcacag tttctgattt ctccacaaga gcaacagcta
     8641 cgcctgaaaa gatggaaaga ctactggaca gatgaaaaac aacagcaaat ccgtaaacaa
     8701 ctggaaacag ctgccactga ataccgtttc cgtccgggaa gcttcgatcc cttttatcaa
     8761 tggctaaacc aacctttcgg tgaatatcac tacaccgcac aagaagacga tttatccggc
     8821 aagctactga acgaatggca aacttctgcc gattccatca ccatgcttat cagccagata
     8881 cggattagcg accagaataa ggaaaccgtg tatcagaact tcagcaaaac ccaggatgta
     8941 gtcatcttcg accgttccta ctttgccaat aaatgggtat ctgccatcaa tgacgacttt
     9001 tacctgattc tgtatatctc ttctttcctg atattcttcg cattatggtt ctcatacgga
     9061 cgtatcgaac ttaccttgat gagttttctc ccgatgctgg tcagctgggt aatcatcttg
     9121 ggattgatgg gaattttggg gattgagttc aacatcatca acattatcct gtccaccttt
     9181 atctttggca ttggagacga tttcagtatc ttcattatgg acgggctaca aaacaaatac
     9241 cgtacaggtc agaaggtact gaattctcac aaaacagcca tcttcttctc tgctttcacc
     9301 acagttgtcg gtatgggagc acttgttttt gccaagcatc cggctttgca atccatttca
     9361 ctgatttcca ttctcggcat gatagcagtg gtgttggtag cctataccat tcagccactc
     9421 attttccggt tcttcattgc aggacccgct tccaaaggat tgccgcctta tacgcttatc
     9481 gggctgatac ggaccgtatt gctcttcctg cttttcttta tcggttgtat cttcctccgt
     9541 gtactgatcg ctgtccttta tttggtgcct gtgcggaaaa gcagcaaaca acgtttggta
     9601 tgccgactga tacaaatcac ctgcaaaggg attctgttgt tagccactgc cgtcaaaaaa
     9661 gaacatatca acaaggccaa cgagcgtttc cagcatccgg caattattat cgccaaccac
     9721 cagtcgttca tcgatattct ggtattgctg tctctttcgt ctaaaatcct gatggtaacc
     9781 aaccattggg tatggcattc tcctttcttc ggagcaatca tccgctatgt cgatttctat
     9841 tacataggcg aaggctacga acaatatatg gaacggatgc ggaaaaaagt aaaagagggc
     9901 tactccatcg ctatcttccc cgaaggtaca cgcacttaca acggaaagat gaagcgtttc
     9961 cacaaaggag ctttctacct ggcagaaaca ttgcaactgg atattcttcc gatcctcctc
    10021 tacggcaaca acaaaatcat tgcaaaggca cagcctttca atatccgcaa aggaatcatc
    10081 tacacggaaa tacttccccg tataccggcc gacgaccttt ctttcggaac cacctaccag
    10141 gaacgcacca aacgcatatc cgcctatatg aaggaaggtt acgcccatat ctgccgggaa
    10201 aagaacacga cggacaatcc tgccttctac gaagctctga tccaaaacta tatctacaaa
    10261 ggaccagtcg tagaatggta tatccgtatc aaggtgaaga tggaaagaaa ctaccggctg
    10321 ttcaaccgac tgattcccgc ccaagggcaa attacagaca tcggctgcgg cttcggtccg
    10381 ctctgttata tgttgtctct gctttccgaa gaccgggaaa ttttaggaat tgattacgat
    10441 gaggataaaa tagctttggc acaacacgga tggttacgca acgaatatct ccagttcagg
    10501 cacggcaacg cattggaata tccgctaccg gaaagcgatg tttttatcct gaacgatatg
    10561 cttcactata tgagctatga acatcaacgg actttgctgt tgaaatgcgc tgaccggctg
    10621 cgttcgcagg gaatgattat catacgggac ggaaactcgg caaatacgtc caaacacagg
    10681 ctgacccggt tcacggaatt actatccacc cgtatcttca atttcaaccg gactaccgga
    10741 gaattgtatt tcaccacaga aacccaacta cgggaaatag cagtcacctg cggaatgaat
    10801 gtagaaatca ttcctaatga caaatatacc tcgaacacta tttatatatt cagaaaaccg
    10861 aacgaacatg agtaaatacg atatcatcat tatcggaagc ggccttggcg gactggaatg
    10921 tggagcgatt cttagtaaag aaggattcaa tgtatgcgtc gtagagaaaa acacgcaatt
    10981 cggcggatgc tttcaaacct accggcgaaa aggacactta ttcgatacag gcattcatta
    11041 tgtaggaagt ctggatgaag gtcaagtgat gaatcagtat ttccgctatt tcggcatcat
    11101 ggacaaacta aagctgaaac gtttggacga cgaggctttc gatacaatct actataaagg
    11161 aaaaacatac gattacgcaa tggggtatcc gcaattcatc gaaacgatct gccggtcctt
    11221 cccgcacgaa aaagaaaacc tgaaacgtta tgccgaacag cttcagactg ttggtaactt
    11281 gattagcgta gaccatctga aacagggcac acttgccctg gaaggaatga aatacttctg
    11341 cacctccgcc gcaggactga ttgcggatat tactccggac cctactttac aaaatgtact
    11401 ggcaggctcg gccttgctct acggaggctt gaaagatgtc tccaccttct acgaacatgc
    11461 catgattaac cattcctata tcgaaggagc ttatcgtttt gtggacggca gtatgcaagt
    11521 cagcctggga ttgattaacg tgatccgggc gaatggaggg acagtactta acaacagtga
    11581 agccacccgt atcatcgttg aaaacgaaaa agtacaggga gtcatcatca acggcaaaga
    11641 gcggttggaa agcgactatg taatttccaa catgcaccct caacgaaccc tggagatact
    11701 ggataaaaac cgtagtatca agaacgccta catatcccgc atccgttcgc tcgaaaacac
    11761 atacggcatc ttcacgcttt atctggtaat gaaaaagaag agcactccgt accaaaaccg
    11821 taacctctat ctgcatggag atcacaaagt gtggtatgac aagcagctct atccgggacg
    11881 gaccaccaac tgcatgattt cgatgcaagc ctcttccgaa gacagtcaat acgccagtgt
    11941 tatttcgatt ctgacaccga tgtatatgga cgaactctct gcatggaaag acaccactcc
    12001 cgaacatcgg ggagaaagct accggtcctt caagcaggaa aagacggaac agttgcttcg
    12061 ctttattcgg agccatggca ttgatttctc cgacaacata gaagagattc acaccaccac
    12121 tccgttgagt tatcgcgact ataccggaac ggtggacggt tccgcatacg gaattatcaa
    12181 agattataaa tgtccgcaaa tcggttttgt gtctacacga agccggttgg gtaatctctt
    12241 tctcacaggt caaaacctga atgtgcacgg cgcactgggg gtaacgctga cttccatgct
    12301 cacttgtgcg gaatttgtgg gacaagaata cctggctaaa aaagtaggaa atgcataaaa
    12361 caatcaaaaa gatattcaag tacacgagct gcgttctttt gtcgctcctt gtgatattga
    12421 tagccggagt ctgttatctc tacttttcag cagatatgcg aacaccgaaa catgaaccca
    12481 gtatcatcat gacaaaagtg tctcatgcag gtactactac catggttccg gcagaggtgc
    12541 tctacaatga tacgctcgat ctccgatatt atgacggcaa cttcctgcgc cacagcgaaa
    12601 gcggattgtg ggagttgttt gtgaaaggag atgcctttca aagaggagaa gccatcggca
    12661 aactgtcttc cgatttgctt cattatcagg agaaagtatt tgtcgatcaa attcgtgaga
    12721 ttgttccttc agacagttat ctgaagttcc tccggttctt tattgtatta ttcaaccgtc
    12781 atttgggtga gaacgttctc gaagaatacc gcaacgagat ctacggaatc tcgctatcgt
    12841 gtacccatga atacgacttt atcggcactc cttacgaacg tcagttgaat taccattcgg
    12901 cacacgacct gggacatgcc atgcaagatt atatgttagt gggatgcagt tcgtttgcca
    12961 cttggggaac acaaagcgcc gattcgtctc tactaatcgg acgcaacttc gatttctatg
    13021 tgggagatgc cttcgcagaa aataaacaag tggcttttta tacaccggat caaggttata
    13081 aattcgcttc cgtaggatgg cccggtatga taggcgtact atccggcatg aacgaaacgg
    13141 ggctgaccgt cacgatcaat gccgccaagt ctgctgttcc aacaggttcc gccactccta
    13201 tttccattct gaccagagaa atcctgcaat atgcgtcaac gattgatgag gcttttgcca
    13261 ttgctaagaa acggaagaca ttcgtctccg aatccatctt gataggttct gccaaagatg
    13321 gcaaagccgc tatcattgaa aaatccccag agaagacagt gctctttaaa gggaaagaat
    13381 ccgaccgact catcagcacc aatcattacc aatcggagga attcagtaag gatgaacgaa
    13441 atatggaaaa tatccgtact tcggacagtc cataccgttt tgcacgattg gaagaactca
    13501 tcaatgaaaa tatgccgata gacgcctcca aggccgcctc tatcctgcgc aaccacaagg
    13561 gtttgcaaga tgcggacttg ggactggcta acgaaatggc tatcaatcaa ttcattgctc
    13621 atcattccgt tatcttccaa ccggagaaac gattgatgtg ggtatctacc tctccctggc
    13681 aatgtggaaa gtatgtagct tatgacctga acaagatatt taacgacacg attaacttgc
    13741 aacacgaaat atacagttct aacctgacca ttccggcaga tgaattcacc gaaacaccgg
    13801 agttccagca tcttcttact tataagaagc tgactccgct cctattgaag aagatcagaa
    13861 aaaaggagaa gatagaagag catgttttaa aaacatacga agcctccaat ccttctctat
    13921 attatgtata tgaagtgatg ggagattatt acgaggctat gcagcaaccg caacaagcca
    13981 ttgcgtactg gcaaaaagca ttgaagaaac cgattcccaa gttgcaagag aaagaacgta
    14041 tccaacagaa aattcaaaaa caatccaaag atggaaaaga atcctgaaat tcagttccgc
    14101 tcaccggaag agatcaaatg ctatcaggaa gaaaagttag ctcaaacgtt gacctacctg
    14161 caagcacact ccaagttcta ccaacgaatg ttcgaagaac accacattga catcaatcag
    14221 ataaagaaga ttgaagactt gcaacaaata cctgtcacca ccaagacaga cttgcaactt
    14281 cataacgacg acttcatctg tgtagacaag gagcaaatca tcgactatgt aacgacttcc
    14341 ggcacactgg gagatccggt gactttcgtt ctcacttccg aggacctgga ccgtttatct
    14401 tacaacgagt acctgtcttt caccaccacc ggatgcagta aaaaggatat tctgcaactc
    14461 atgactacca tcgaccgccg cttcatggcc ggacttgcct attacatggg agcacgcgaa
    14521 ctcggcatgg gagtgatccg tgtaggtaac ggcatccccg aactgcaatg ggacacgatt
    14581 cgccggattc atccgacttg tggaatggtc gttccttctt tccttatcaa actgatagag
    14641 tttgccgaga agaatcatat cgaccataat gcgtgctcaa tgcagaaatg tatctgtatc
    14701 ggtgaggctt tgcgcaatca ggagtttcag ttaaatacgc tcggacaaaa gatacatgac
    14761 aaatggtctg ccttacagct atattccacc tatgcttcca ccgaaatgca gtcgtctttt
    14821 accgaatgta gcgaattcca cggcgggcat ttgcaaccgg aacttatcat cgtagagttt
    14881 ttggatgaca acaatcgtcc tgtcgcagag ggagaagctg gcgaagtgac gatcacgacg
    14941 ctcggagtag aaggtatgcc gctgctccgc ttcaagacag gtgatatttg ttaccatcat
    15001 accgaacctt gtgcctgcgg aagaaatacg attcgcctta gttccatcct cggacgaaaa
    15061 gggcaaatga ttaaatacaa agggactact ttgtatccgc ctgcattgtt cgacatactg
    15121 gacaatattc cttcggtaaa gaattacatc attgaagttt acaccaacga attgggaacg
    15181 gatgaaattc tgatccgtat cggaagtgaa aaccgtagcg aaggttttgc caaggagata
    15241 aaagacctgt tccgttcgaa agtaagagta gctccaagca ttaattttga gtcggcagaa
    15301 tacatcgcaa aaattcaaat gcctccaatg agtcgaaaaa cgataaaatt cattgattta
    15361 cgataattat tttctacttt tggaagttag taaaccaact atatcacttt aacattaacg
    15421 tatatgaaaa aacttattct attcttattc ttaagtacga gcctgttctg tttcggacaa
    15481 ggcaagagtg cattgaaaga catccagtct atcaagttct atggagtgga ctactcccaa
    15541 gctaaagttt tcggtgcaga tgaatcaccg atacaattca aagatgcttt cagacgtatc
    15601 aatgagctgt ttatcacaga agcaaagaag tataacgtag gaaaacagtt gaaaaaagaa
    15661 gtaacggaaa tctcactgga tgcagtcaat caagtgaacg aaaacattaa cttggccgag
    15721 ctgatgacta ccaaaagaga atatagcctt agtaaagaac aaatcaaagc ggctatcgaa
    15781 gcattaccta ttcagaaaac gccgggcgta ggtatggtat ttatcgcaca gttcctggat
    15841 aaatcaaaca acagaggtac gtatgaagtc gtattcttca atactgaaac aaaggagatc
    15901 attgaagaat ggataacaga tggaaaagca cgtggtttcg gattgcgcaa ctactgggca
    15961 ggatctgttt atagcgcact aaagaaatta taaaccaata atatatataa acatgagaaa
    16021 actactatta ttgctgactt tactgttaag tatcagtact tatgtcgcag cacaaaatta
    16081 cacagaagta gtgtatttaa agaatggcag cattatcaaa ggggttatca ttgagcaagt
    16141 gcccaatgtt tccttaaaaa ttaaaacaag tgatggcagc ctcatcatct gtcagatgag
    16201 tgatgtggag aaaatcacta aagaagaacg gtatacaaga gattaccgca aagaggccaa
    16261 caaccgcaaa gccgcaagaa atacattaaa aggctataaa ggtttcgtgg actttgcata
    16321 catcggtgat gtcagcgact acaatgcctc caaaattgaa ttatcaacct cacacggtta
    16381 tcaattcaat aattatttct tcgttggtgg tggtgttgct ctcaactact atacagatgc
    16441 agatcttgtt gctgcgccaa tctatgctaa cttcagggct aacttcatca acaaaagagt
    16501 gacgcctttt gccgatgtaa aaaccggata tgctgtagga gacatagaag gagcgtatgc
    16561 ttcgatagga gtaggagtac gtttttcttt aaaagggaaa aaggccttga atttagcttt
    16621 gatgtataac ttccaggatt atgagatctc aacagattat ggttacagtt ccggaggtta
    16681 ttattaccat tccagttatg acgatacatg ggagttacac ggagtagggg tcagattcgg
    16741 ttttgaattc taaatctact gtttgtctgt accttttaac aacaaacaaa caataaatca
    16801 aattcgaacc atgaagaaga ctatcacaac acttctacta ttgagctgca ttactgcatt
    16861 ttcatttgcg caaagcattg ttatgacttc aggaactatc gacttcatca aggaccaaca
    16921 agtgatacaa ttcactttct cttatgatga aatgctggta ggaaaactaa cagaaagcga
    16981 atatgtagat aaaaagagct ccgaatataa tgcaaaagaa gagggcaaag gagatcaatg
    17041 gaaagctgcc tggtatggcg accgtaaaga acgatttgag ccaaagttct tggaactttt
    17101 cgataaatat atgagcgaag ttggtatcac agcaggtacg gaaggcgctc aatatcgaat
    17161 cgaaatcaat acagacttca ccgagccggg ttggaatgtg ggtgtcatgc gtcagaatgc
    17221 atctgtcgac ctaagctgca aagtgaagaa gattgaaacg ggtgagcaag tagcctctat
    17281 cagaatccgt aatgcttctg ccaacaactt ttggggtact gatttcactt ccgggtatcg
    17341 cgttcaggaa acgtatgcca aagcaggaag agaattagcc aagttcttta tcaaaaaggc
    17401 gaagttgcac aagataaaag actaactggc ttgaaccaca tttgcctact ataaagttga
    17461 aaaaacatag aagtatctgc cacctgcaac aaaaagcgcg taatacacta gctgacaaat
    17521 agttggagcg ttgcagatac ctgcggcaga tacgttgcag ataaagtatc tgcaacgcgt
    17581 tatataacca aagaaaaccg cttggtttct atatgtaaag ctataagata gttttggtat
    17641 ccagacggag aaacggcagt ttccatacat aggaactgtc gtttcctgcc ttggaaacgc
    17701 tcgtttccta ccgtggaaac tacagtttct aataccggaa actccagttc cccgcctgga
    17761 aactggagtt taatgcattt aataaacttt cgtactcata ggaaataggt ttatgtatgg
    17821 attatacagt gtggcagata ctctatctgc aacgcatctg caacaggtat ctgcaacgct
    17881 acaactagtt gtaaactaat atattatacg cgttttgttg caggtggcag atacttcaat
    17941 gttttttcaa ctttatggag gaaggaatat atcacaatta tgctcataac tgtaaaacag
    18001 ttggatgaag cactctccca tccgttattg agctaaataa atactctcat taaagagtag
    18061 tattaatgaa tataaagaat attaggcacc ttacgctccc cagcatggtc aaaccgccca
    18121 ttatcacaag gataattgac gactccatca tccgatgcac cggacagcca aagggtagta
    18181 gacccgcctc catccaaatt taacgcatcc tcacctccta aaatacgaat caaatgtgcc
    18241 agttccggaa tattcactcc ttcggcttgc tccgggaaac gtccgtctac ggttatcaac
    18301 aatattttcc cctccttagt ggtggcaaca gcactacgag gatgcttggt tcggataaaa
    18361 ttcgtgccac atgaattcca atcgcaaatc tgtccgtctt tcagcattag cggaccggaa
    18421 gcaagtacta tacctgtttc ccctttgtat tctttttcta tctgcctgct ccagggaatt
    18481 aactttatct tccctttatg tacatgcata gctcctgtga cacgcagttt acattcgctc
    18541 aaagtggttg tgtcaacaac ctgattgccc actttcagga aacaaaccga atttccccgc
    18601 ttcatatcaa agtaggaacc attaattgct gcaataccac gatgttctga agcaatccgg
    18661 ctcgtctctt tcatctcacc cgaaacggca atatcgactt tcaaacctgc gccggggtct
    18721 atttctatca gactaacaga ctgggtccct tgatataatc gagggataga agcatactta
    18781 tgaattattc ctttttgagg actttccact ttccatcggg cagacatgat cgccagtgaa
    18841 tccgacacag tttgcccttt tattattccg atagaacata aaatcaggat agcgattaac
    18901 aagtttcttt ttatcataaa cagagaaatc tcacaaattt aattctttgc actttttaca
    18961 aagataggca aaagaaatca gcctccaaaa agtcagcctt gaaatatttt cgtcttatct
    19021 actatacact tccgcttttt ttcgtacttt taccccttgt tgggaagaag tgcctttcca
    19081 acccttgaga acagaaaaag aaaaaacaat atataaaatg aatcacaaat ggaattatcg
    19141 acccattaca cccgaacagg cagagacaag ccagacattg gcccaggaat tagggattag
    19201 cccgattctt ggacaacttt tggtacagcg gggaattacg aaggcagcag atgccaagaa
    19261 gtttttccgc ccgcagttgc ccgacctgca cgatccgttc ctgatgaagg atatggatat
    19321 tgcagtagaa cgtctgaaca gggcgatggg aaagaaagaa cgtattctaa tttatggaga
    19381 ttatgacgta gacggtacta ctgccgtggc attggtctac aagtttattc aacagttcta
    19441 ttcgaacctt gattactaca tacccgaccg ctacaacgaa gggtatggca tttctaaaaa
    19501 aggagtggac tacgccgctg aaaccggtgt gggactgatt attgtactcg attgcggaat
    19561 aaaagcagta gaggaaatca cgtatgccaa agaaaaaggg attgacttta tcatttgcga
    19621 ccatcacgtg ccggatgata ttctcccgcc tgccgtagct atattgaacg ccaaacgcct
    19681 ggacaacacg tacccgtaca cccacctttc cggttgtgga gtcggtttca agtttatgca
    19741 ggcgttcgcc attagtaacg gtatcgaatt ccatcatctg attccgttgc tcgacatcgt
    19801 agccgtgagt atcgcatcgg acatcgttcc gattatgggt gaaaaccgta ttctcgccta
    19861 ccacggtctg aaacaactga acagtaaccc gagtatcggt atgaaggcca ttatcgatgt
    19921 atgcggactt tctgaaaaag aaatcactgt cagcgatatt gtgtttaaaa tcggaccgcg
    19981 catcaatgcg tcgggacgta tccagaacgg aaaagaagca gtagacctgc tgacggaaaa
    20041 agacttctcg gtggcacttg agaaagccgg acaaatcaac cagtacaacg aaacccggaa
    20101 agacctcgac aagagtatga cggaggaagc aaacaacatc gttgccaatc tggaaggatt
    20161 agccgaccgc cgctctattg tgctctacaa cgaagaatgg cacaaaggag tgatcggcat
    20221 cgtagcttcc cgtctgacgg aagtgtatta ccgccctgcc gtggtattga cacgaacgga
    20281 tgacatggcg acaggttccg cacgttctgt ttccggcttc gacgtatata aagcaatcga
    20341 gcattgccgc gacctgttgg agaacttcgg aggacataca tacgccgccg gactatcaat
    20401 gaaagtggag aatgtggatg cttttaccaa acggttcgaa gactacgttt cacggcatat
    20461 cctgccggaa caaaccagtg ccgtcatcga aattgatgct gaaatcgact tcagggatat
    20521 ttcttccaag ttcttcaacg acctgaaaaa gtttaatcct ttcggccccg acaacacgaa
    20581 acccattttc tgcactcatc acgtctatga ttatggaacg agtaaagtag tgggacgcga
    20641 ccaggaacat atcaagctcg aactggttga taataaatcg aataatgtaa tgaacggtat
    20701 cgcgttcgga cagagttcgc acgtgcgcta tatcaaaacg aaacgttcgt tcgacatctg
    20761 ttacaccatt gaagaaaaca cgcacaagcg tggcgaagtt caacttcaaa tcgaggatat
    20821 aaagccgatt gaataagtat caggagatat taaaacaata ttggggatat gactccttcc
    20881 gcgacttgca ggaggagatc atcaccagta tcggcgaagg caaagataca ctggggctca
    20941 tgcctacggg aggcggtaag tccatcacct ttcaagtgcc tgctctcgcc caggaaggga
    21001 tttgcattgt catcactccg ctcatcgccc tgatgaaaga ccaggtgcag aacctccgca
    21061 aacgcggtat caaagccctt gccgtatatt ccggcatgac gcggcaggaa attctcactg
    21121 cacttgaaaa ctgcatcttc ggtgattaca aattcctcta tatttctccg gaacgtctgg
    21181 acacggacat attccgcacc aaactgcggt cgatgaaagt ctctatgatt acggttgacg
    21241 aaagtcactg tatctcacaa tggggatatg acttccgccc cgcttacctg aaaattgccg
    21301 agatacgggc gctgttaccg ggaattccgg tactggcact gaccgccacc gccactccgg
    21361 aagtggtgaa agatattcaa gctcgcttgg atttccgtga agagaatgtt ttccgcatga
    21421 gtttcgagcg gaaaaacctg gcgtatatgg tacggcaaac ggataacaag actcaagaac
    21481 tgttgcatat cttacgaaag gtaccgggca gcgccattat ctatgtccgc aacagacgac
    21541 ggaccaaaga aatcaccgaa ttactggtaa atgaagatat caccgccgac ttttatcacg
    21601 ccggactgga taatgccgta aaggacctcc gtcaaaaacg ctggcaaagc ggagaagttc
    21661 gcgtgatggt agctaccaat gcctttggca tggggatcga taagcctgat gtgcgtatcg
    21721 tattacatct tgacctccct gattctctcg aagcctactt tcaggaagcc ggacgtgcag
    21781 gaagagacgg tgagaaagcg tatgccgtaa tcttatatac taaaacggac agaacgacgt
    21841 tacacaggcg tgtagtggat acttttcccg ataaagaata tatcctcaat gtgtacgagc
    21901 atctgcaata ttactatcag atggcaatgg gcgacggttt ccaatgtgta cgtgaattta
    21961 acctggaaga gttttgccgg aagttcaaat acttcccggt tccggtagac agtgcgctga
    22021 agatactgac tcaagcaggt tatctggaat atacggacga acaggacaac gcttcccgta
    22081 ttctttttac gattcgccgg gacgaactgt acaaactgcg ggaaatggga acggaagcgg
    22141 aagctctgat acagatgatt ctccgttctt acaccggagt gttcaccgat tatgcctata
    22201 tcagcgaagc caccctgtcc gtacgtaccg gactgacccg cgaacagatt tataacatat
    22261 tggtcacgct taccaaacgt cgcatcgtag attatattcc gcacaaaaag actccttata
    22321 ttatatatac acgcgaacgg caggaacttc gttttgtgca catcccccct gctgtctacg
    22381 aagagcgtaa agcccggtat gaagctcgca tcaaggcgat ggaagaatat gtcatttcgg
    22441 agaat
//
