LOCUS       c00173_gnlPro..         9644 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ODKKLADI_173.
ACCESSION   c00173_gnlPro..
VERSION     c00173_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 00:41:26
            Original ID  :: gnl|Prokka|ODKKLADI_173
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9644
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9644
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2552:7412]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2553..7412
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..9644
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9644
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(197..1333)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 57.1; E-value: 4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg173_1"
                     /sec_met_domain="AMP-binding (E-value: 5.2e-19, bitscore:
                     57.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRKQQRLLLEGKEYTFEDISRLIAGGAEAHSPASWDLYLFLN
                     EWFNDSPVIIVHTSGSTGTPKELIVRKDQMMQSARLTCEFLDLKKGETALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKEPLRFVAMVPLQVYNTLQVPEEKERLKQTD
                     ILIIGGGAIDEALEAEIKHLPTAVYSTYGMTETLSHIALRRLNGTLASEHYYPFSSVKL
                     SLSVENTLIIDAPLVCDEILQTNDIARIYPDGSFMILGRKDNVINSGGIKIQAEEMEKL
                     LRSFIPVPFVITSVPDQRLGQAVTLLLEGQPELLEGQPDTKEIGNKLQEILEPYYRPKY
                     IWTTDCIPQTENGKVNRAKCRILAKQMLTTFYTHTLTP"
     CDS             complement(1355..2380)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg173_2"
                     /sec_met_domain="MR_MLE_C (E-value: 1.3e-28, bitscore:
                     89.1, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNCKIEIIPRLLHFKQPAGTSRGTYTTRKVWYLHFTSPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILVKVCRKVEREQGRLDMDGLCDYPSILFGLETAIRHFF
                     AGNWALCDTAFSRGEVGIPINGLIWMGDFQNMLSQIEKKMEAGFRCIKLKIGAINFEEE
                     LTLLRHIRTHFSSKEIELRVDANGAFSPVDAMEKLKRLSEFDLHSIEQPICAGQWEEMA
                     RLAAESPLAIALDEELIGCNTLERKQELLSTIRPQYIVIKPSLHGGICGGDEWITEAEK
                     QQIGWWITSALESNIGLNAIAQWCATFSNPLPQGLGTGALFTDNVEVPLEIRKDCLWFC
                     K"
     CDS             complement(2553..3377)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg173_3"
                     /sec_met_domain="ECH_1 (E-value: 7.3e-83, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             complement(3381..5048)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg173_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7e-08, bitscore:
                     21.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYPVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVIISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINVPISEPLFQFTVDSLPEVRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMN
                     LIYLFEKRYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKVGQMVPELLIT
                     YGGHVVSKRLKKFLRQHPPKEHWHVSPDGEVVDLYGSLTTVIEMDPFEFLEKIASLLDN
                     RTPEYPRVWENYCKIIPEPEFAYSEMSAVGTLLKALPESCALHLANSSVVRYAQLYSIP
                     STIEVCCNRGTNGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNVNVRSNLRV
                     LLLNNGGGEIFHTLPGLDMSGTSHKFIAAVHKTSAKGWAEERGFLYLQAQNDEELAEAM
                     KTFTQPEAMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             complement(5068..6183)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg173_5"
                     /sec_met_domain="Chorismate_bind (E-value: 3.3e-58,
                     bitscore: 186.3, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVRL
                     IYDLKELNGQRGFVIAPFQVSESCPVVLIQPDQWGQPLPVDDDTEEDREIALRLQGQES
                     FLTSSTEEYAACFHTFINALRDRTFDKLVLSRHLTVDKVADFSPLSIFRAACKRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWHTVALAGTQPLQDGRLPQVWDEKNRKEQDYV
                     ASYIRRQLLSLDIHSTENGPYPAYAGALSHLKTDFRFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYQFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMHIEDKQLTLYAGGGL
                     LASSELNDEWLETEKKLQTIKRLIAVPPLKS"
     CDS             complement(6180..7412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg173_6"
                     /sec_met_domain="HBT (E-value: 1.2e-18, bitscore: 56.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNG
                     FALFTYHDDTIITDSPENEHIQNEARLNNLQIIKEEEFSAAVDFAPCKCMLVSDDEEAL
                     VGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLDVKREEVIAVGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKACADYVTASNEEDGVAVAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALAETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(7497..7859)
                     /locus_tag="ctg173_7"
                     /transl_table=11
                     /translation="MIQVRIKRVYDDFSETDGYRVLVDKLWPRGMKKEWLKYDYWAKDI
                     TPSSTLRRWFHEDIPGHWEDFVIQYQKELDASSSMADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMRLKE"
     CDS             complement(7925..9643)
                     /locus_tag="ctg173_8"
                     /transl_table=11
                     /translation="DQPRSRGLGDVYKRQLYTEKYIRNIYIPEPRRALQLLDEAENRKT
                     IPLRVVNELRSLSYSNMYMNKLAFMYARKAYLLDSLYQKDPKHMLKMTVHLAEFSAMMS
                     KYNESMRYALDGIRQAQELGNREAKARLFFCMGENNWRLSFKDKAYDYFNRTIELLRGS
                     KEKREMMLLSYYYGAEMSFLMNDSRIEEALKVGFEREKQIERLKAVPQISEDYIDGQYS
                     YLYAKLAYIYCMEKKYEKAEQYYQKYLSKKESHTPDGKMYSVPYLVLSGQYEKVIDNCR
                     GFKELMRTQQDTLNEQYLTVLRQEVKAYLGMHKYKEAAEIRETILTITDSINTRDRNNA
                     ALELNAMYGVSEKEEYIAEQAFQLKIRNITLCFLACIVVLTLFVVWRLWHFNHIVEYKN
                     RMLARLINEKFANRKDGNQLSEVYEQLAVVSEIEPERISPEELEELANDTDKESGEEEE
                     NKKIFQELNDIVIRKQLYLSSELSREDLAQIVHLNNARFARMIRECTGTNFNGYINELR
                     INYAIELMKKHPNYTIRAIADEAGFNSTPILYNLFKKKTGMTPYEFKKAQDSLQN"
ORIGIN
        1 tctacaccta ttaagtcgtc ggcagcgtca gatgtgtata agagacagaa agtaagcaac
       61 aactttcaaa agatgaaact tattctactg aaataaaatg tcttaccctg aattttgttg
      121 actctaataa gtctcaacta aaactagggt aagacaatta gaggcccctg aaacgttgat
      181 gaataaagga tttcaatcaa ggtgtgagag tgtgagtgta aaacgtcgtc aacatttgtt
      241 tggctaaaat acgacacttc gcacgattaa ccttgccgtt ttctgtttgc ggaatacaat
      301 ctgtcgtcca tatgtacttg ggacgataat aaggttccaa tatttcctgt agtttgtttc
      361 cgatttcttt agtgtccggc tgaccttcca ataattctgg ctgaccttcc aatagtaagg
      421 ttacagcctg ccctaaacgc tggtccggaa ctgaagtaat aacaaatggc acaggaataa
      481 aagaacgaag caatttctcc atttcctccg cctgaatctt aattcctcca ctatttatca
      541 cattgtcttt ccgacccaaa atcataaaac ttccatcggg atagatgcgt gcaatgtcat
      601 tggtttgcaa tatttcatca cataccaaag gggcatcaat aattaacgta ttctctacag
      661 ataaagacag ttttactgaa gaaaacggat aataatgttc cgaagccaat gttccgttca
      721 gccgacgaag agcaatatga gataaagttt cagtcatgcc ataggtagaa tagacggcag
      781 tcggaagatg tttgatctcc gcctctaaag cctcatcaat agctccacca cctataatca
      841 aaatatccgt ctgtttcaat cgttctttct cttcgggaac ttgcaacgta ttataaactt
      901 gcaggggaac cattgccaca aatctcaaag gctcttttat atccgctaaa ggatgaccgg
      961 aagcaggacg tacaatcaaa ttcaagcctg caaccaacga acgcacgacc accatcattg
     1021 caccaatata acgaagattc atacaaagta atgccgtctc tcctttcttc aaatccagaa
     1081 actcacaagt cagacgcgca ctttgcatca tctggtcttt acgtacaatc aactctttag
     1141 gtgtacccgt agagcctgat gtatgaacaa tgatgacagg agaatcgtta aaccattcgt
     1201 tcaggaaaag atataaatcc caactagcag gagaatgagc ctccgctcct cctgctatta
     1261 atcggcttat atcctcaaaa gtatattctt ttccttccag taacaagcgt tgttgttttc
     1321 gatcgaatat catcggaata tcctttaaat actatcattt acaaaaccat aaacaatctt
     1381 ttcttatttc aagaggcact tccacgttgt ctgtaaagag cgcccctgtt cccagtccct
     1441 gtggcaacgg attgctgaat gttgcacacc actgggcaat ggcgtttagc ccaatgtttg
     1501 attccagagc ggaagttatc caccagccga tctgttgttt ttcagcttcg gtaatccatt
     1561 cgtctcctcc gcatattcct ccatgaagag aaggtttaat aacgatatat tgcggacgaa
     1621 ttgttgaaag cagctcctgt ttcctttcca gcgtattgca tcctatcagt tcttcatcca
     1681 aagcaatcgc taatggagat tcggcagcaa gccgagccat ttcctcccat tgtccggcac
     1741 agattggctg ttcgatagaa tgtaaatcaa actcggacag acgtttcagt ttttccattg
     1801 cgtccacggg tgagaaagca ccatttgcat ctacacgcaa ctctatttct ttagaagaga
     1861 aatgcgtacg aatatggcgc aacaatgtca gttcttcttc gaaattgatg gcacctatct
     1921 ttaacttgat acaacgaaat ccggcttcca tctttttctc aatctgggat aacatgttct
     1981 gaaaatctcc catccaaata aggccgttaa tcggaatacc aacttctcca cgtgagaaag
     2041 ccgtatcaca taaagcccag tttcctgcaa agaaatgccg gatggccgtt tccagaccaa
     2101 ataaaattga aggatagtca cacaagccat ccatatccaa tctgccttgt tccctctcta
     2161 ctttccggca gactttcact aatatatctt cgtaatcagg aagatcgtca caacttaaag
     2221 cgggcaaagg tgcacactcc cctattccca ctctgccagg gaagtcagga gaggtaaaat
     2281 gaagatacca aactttacgc gtagtatatg ttcctctgga agtcccggca ggttgcttga
     2341 aatggagcaa tcggggaata atttctattt tacaattcat cgtgaataat ttttcaattc
     2401 accacagaat aacacagagc ctcacgaagt tttaataagt tatatctctt gcagttctcc
     2461 taccattctc tcctccacag tcttgctttg cagaaaatcg ggcttaaacg caggaaaagc
     2521 aaactctgtg gtactctgtg gcaaagccga ttttaaggga atttcggata ttgtttgaag
     2581 ttcggtttac gtttctccag aaacgcattc tttccttcct gtgcttcatc agtcaggtaa
     2641 tagagcaacg ttgcgtcacc tgccaattcc tgaatacctg cttgaccatc cagttcggca
     2701 ttcaatcctg ctttaatcat gcgcaaagcc aacggactaa gcagcatcat ttcttctgcc
     2761 cactgcacat attcatcttc caactgctcc aagggaacta ctttattcac taatcccata
     2821 tccaatgctt cttgtgcatt atacttccgg cagaggaacc agatttcgcg tgctttcttc
     2881 tgaccgacca cacgtgccag ataagacgca ccgaatccag catcaaagct acctacacga
     2941 ggacccgtct gaccgaaaat agcattttcc gacgcaatgg acaaatcaca taccacatga
     3001 agcacatgtc cgccaccaat agcaaaaccg ttcacggcag caatcaccgg tttcgggatg
     3061 ctgcgaatct gcttttgcac atccaatacg ctaagacgag gcacaccgtc ttttccgata
     3121 tatccgccac gtcctttcac attctggtcg ccgcccgaac aaaatgcctt atcaccggct
     3181 ccggtaatca caatcacatc aatatccgct tcttcacggc agatgcgcaa tgcgtcactc
     3241 atttcagcag tagttgtcgg agtaaacgca ttccgatagc gttcacggtt gatcgtgata
     3301 cgggcaattc cattataata atcaaaaaga atatcgtcgt attctctaat ggttgtccac
     3361 tctctttgtg ttgacataat ctatttttgt tttaattgat gataataatt cttcaacatg
     3421 cgcgcgtcct tgtttttgtt ggtaaacacc tccaagagca caggctgttc catagcttcc
     3481 ggttgagtga aagttttcat cgcttcagcc agttcttcgt cattttgtgc ttgcagatag
     3541 aggaatccac gttcctccgc ccaacctttg gccgacgttt tatggactgc cgcaataaat
     3601 ttatgtgagg tacccgacat atccaatccc ggcaaggtat ggaaaatctc tcctcctcca
     3661 ttatttaaca gaagaacacg cagattggag cgaacattga cattccacaa tgcattcata
     3721 tcatagaaaa agctcaaatc tccgatagct ataaagttca gtttgtcgga agctgccgca
     3781 taaccgacag ccgtagacag tgagccttca atgccgtttg tcccccggtt gcaacaaact
     3841 tcaatcgtag aaggaatgga gtataattgc gcataacgca ccaccgaact gtttgccaga
     3901 tgcaacgcac atgactccgg caaggctttc aataacgtac cgacggcaga catttccgaa
     3961 taagcaaact ccggttcggg aatgatcttg caatagtttt cccacacacg gggatattca
     4021 ggagtccgat tgtccagcaa actggctatc ttctccagaa actcgaacgg gtccatttcg
     4081 atcaccgtag ttaatgagcc gtacaaatcg accacctcac catccggcga tacgtgccaa
     4141 tgttctttag gcggatgctg acggagaaac ttcttcagcc gtttggaaac gacatgtcct
     4201 ccataagtaa tcaacaactc cggaaccatc tggccgacct tctcttcggg catggcataa
     4261 agcgccgcat caaagttctt taccggaata ccgggaactg tctggttgcc gatatgttca
     4321 gtcaaccagg caaaatgttt atataataac ttgatatatc ttttttcaaa caggtagata
     4381 agattcatct gaccgatgat aatcattcgc ttctggtatt tattcatccg atcgaccaaa
     4441 tcattataat cacgatcgta gacgttcaac ccctgataac gggtaatgac acgcacttca
     4501 ggaagcgaat caaccgtaaa ctggaacaac ggttcagaaa tagggacatt aatatgtacc
     4561 ggtccttttc catgatggtt cgtttccagc aaagcttcat tcaccagacg attgcaatac
     4621 cattcatctt cttccgtatg aatctccgga aggtttactg acttcttaac caatgtctga
     4681 aatacgcctg gttgtggtac tgtctgtcca tccatctgcc cgatccaggc agcgggacga
     4741 tccgcagaaa taatgaccag aggaacattt tgataaaatg cttctgccac agccggatga
     4801 aggtttaata atgcagtacc ggaagtgcaa cagacagctg cgggcttacc accattcaac
     4861 gcaagaccga tggcaaaata gccggcactc cgttcatccg tcaccggata gcaggtaaaa
     4921 ttcggatggt tagacaaagt atgtactatg ggcgtattac gactacccgg acacaataca
     4981 accttagtaa tcccatgcgc ctcgagcaac gcaaccaact ggagtatgtt cttcttgtct
     5041 gtatacatga tgataattat tagtagttta tgattttaaa ggaggcactg caatcagccg
     5101 tttgatggtt tgcaacttct tctccgtttc cagccattcg tcattcaatt ccgaagaggc
     5161 caataatcca ccgccggcat aaagagtaag ttgtttatct tcgatatgca tacagcgtaa
     5221 gtttacatag atgtctgttc gtccttccgg atcgagccat ccgataaagc cggagtaata
     5281 gcggcggtcg taaccttcat tctgcaaaat aaactgatag gcttcttcct tcggcaagcc
     5341 gcatacggca ggtgtcggat gcaaaacttt cagaaggtct cccaaacctt tattatcttt
     5401 caaagaaaaa cggaaatcag tttttaaatg tgacaaagca ccggcataag caggatatgg
     5461 cccgttttcc gtagaatgaa tatccagtga aagaagctgc cgacggatat aagaagcaac
     5521 ataatcttgt tctttccggt tcttttcatc ccatacttgc ggcaatctgc catcttgcaa
     5581 aggctgtgtt ccggctagtg caaccgtatg ccattcgtct ttctcacctg ataaaatgat
     5641 ttcgggagta cttcccagcc agatgcccgt ctgcggagta taacataagt aaatatacga
     5701 atgaatataa cgtttacaag ccgcccgaaa gatggacaaa ggagaaaaat ccgcaacttt
     5761 atcaactgta agatgacggg aaagcactag tttatcaaac gtcctgtcac gtaacgcatt
     5821 tataaaggta tgaaagcatg ccgcatattc ttccgtagaa gaagtcagaa atgattcttg
     5881 tccttgcagg cgcaaggcta tctcccgatc ttcttccgta tcatcatcca cgggtaaagg
     5941 ctgcccccac tgatcgggtt gaatcaacac aaccggacat gactcactca cctgaaacgg
     6001 agcaattaca aatcctctct gtccattcag ttctttcaaa tcgtatatca aacggaccgc
     6061 tccttccgcc tgcgtcaaca gacggggaac tttctctccg ggaatacggt aaacagcaaa
     6121 cggctgcttc cgctgaataa atgcatcaat agttgtcaag ttacttattt cttcgtcggt
     6181 catctctttt tcatcacact gttgactacc cgtatggaag acaccagttt gtttgttgaa
     6241 gtaaacacgt ctacattcca tacgtgggag gaacgtcctt tatgtacaac tgttcctact
     6301 gcacgcacgg tatctccttc atgtgcagaa gatatatggt ttccgctgac ctgcattcct
     6361 actacaatct cgtccggctg gcaaagaatc atcgaaccga gtccggcaac tgtttccgcc
     6421 aacgcaagag tagctccacc atgcaaaatg ccaaaaggct gacgggtacg atggtctacc
     6481 ggcatcgttg cttccacacg atcttcgtcg gcgtatgtat attgaattcc caagtttccc
     6541 attaatgcgt ggcgtgcctg cgcattcagt tggtcaaggg gaatttcggc tgcacgcact
     6601 tcggctatga tagctttctc cactgcaacg gccactccgt cttcctcatt cgaagcagtc
     6661 acatagtcgg cacaggcttt gaccgagtct tgtgaatgtc ccatagctac acccagcccg
     6721 gccaactgaa tcattgttac atcacacaca ccgtcgccca cagcaatcac ttcctcacgc
     6781 ttcacatcca gcacctccag caaagcaccc aaagaattgg ctttgtcgat ggcgcaggga
     6841 actacttcca gaaaatatgg ctccgaacgg aatacgtcca acgctccgtt caatcgtctc
     6901 ttccagtgat cttccagacc aaccagtgct tcttcgtcat cgctcaccag catacactta
     6961 caaggagcaa aatcaacggc agcagaaaat tcttcttctt taattatttg caggttattc
     7021 aaccgggctt cattttggat atgttcattt tcaggagaat ccgttatgat cgtatcatca
     7081 tgataagtga ataaggcaaa accgttttta cgggctttct tttccagata cggcaacatt
     7141 tcgggattaa tccgacgttc aaacagaatt tccccgtttt gtgcattgat aatctgacag
     7201 ccattatagg aaaggataaa acctccatag tttccaagtt caagcatctt ggccagcggc
     7261 atcaggccat aagtaggtct gccggatgcc agcacaatac gtactcccat ttgctgaacc
     7321 ttcaacaggg cagccaatgt acgcttacta atttctttcg catcattgag gagtgttccg
     7381 tctacatcaa gaaccaataa tttatacttc atgattacac gattttgatt tagattacaa
     7441 aggtaggaaa ttgagtgaac gacagaaagc gtaaacagat aaaaattact ttaatttcac
     7501 tctttcaaac gcatttccag ataatcgcgg aggatacggg catgattata caccggttct
     7561 ttggaagcgt aaagcaatgt tatcaccgga tgcggcttga taagagtcag aaaatcagcc
     7621 attgaggaag aagcgtcaag ttctttctga tactgtatga cgaagtcttc ccagtgtccg
     7681 ggaatatctt cgtgaaacca tctacgcaat gtggaagacg gtgtgatgtc ttttgcccaa
     7741 taatcgtact taagccattc tttcttcatt ccacgtggcc ataatttatc taccagtacc
     7801 cggtagccat ctgtttctga aaaatcgtcg taaacccgct ttatccttac ctgtatcatt
     7861 tctattaata gttaattata aatagataaa ccggaaaatg cgaaaattgt ttagcagaat
     7921 ccactcaatt ctgtaacgaa tcctgtgctt ttttaaattc gtaaggagtc attcccgtct
     7981 ttttcttaaa aagattgtat aaaatcgggg tgctattaaa tccggcctca tccgcaatgg
     8041 cacgtatcgt ataattagga tgctttttca tcagttcaat ggcataatta atgcgcaatt
     8101 cattgatata tccattaaaa ttggttccgg tacattctct tatcatcctc gcaaaacgtg
     8161 cgttattcag atgtacgatt tgtgccagat cttctctcga caattctgaa gaaagatata
     8221 actgtttccg aataacgata tcattcagtt cctgaaatat cttcttattc tcttcttctt
     8281 ccccactttc tttatctgta tcgttagcaa gttcttccaa ttcttcgggt gaaatacgtt
     8341 ccggttcaat ctccgacaca acagccagtt gttcgtatac ttccgatagc tggttcccat
     8401 cttttctatt agcaaatttc tcgtttataa gcctggcaag catcctgttc ttatactcga
     8461 ctatatgatt gaaatgccac aaacgccaaa cgacaaacag agtcagtaca acaatacatg
     8521 caagaaaaca gagggtaata ttccttattt ttaattgaaa agcctgttcg gcaatatatt
     8581 cttctttttc agagacgccg tacattgcat tcaattccaa tgcagcattg tttctatccc
     8641 gggtattgat actatctgtt atagttaaaa tcgtttcacg tatctcggca gcttctttgt
     8701 atttatgcat acccaaatat gccttcactt cctgtcgaag gacagtcaga tactgttcat
     8761 tcaaagtatc ctgctgggtt ctcatcaatt ccttgaaccc cctgcaatta tcaataacct
     8821 tttcatattg tccggaaagc actaaataag gaaccgagta catttttccg tcgggagtat
     8881 gagattcttt ctttgataag tatttctgat aatattgctc cgccttctca tatttcttct
     8941 ccatgcaata gatgtaggct aatttggcat ataaataact atattgaccg tctatataat
     9001 cttcagagat ttgaggtact gccttaagcc gttcaatttg cttttcacgc tcaaaaccca
     9061 ctttcaatgc ctcttcaatt cgagaatcat tcattaaaaa gctcatttct gctccatagt
     9121 aataagagag caacatcatt tcccgcttct cctttgagcc ccgcaaaagc tcaatagtcc
     9181 ggttaaaata atcgtatgct ttatctttaa aagataatct ccaattattc tctcccatac
     9241 agaaaaataa cctggctttg gcttccctgt tccctaactc ttgcgcctgc ctgattccat
     9301 ctaatgcata acgcatactt tcattatatt tgctcatcat tgccgaaaat tcagccaaat
     9361 gtactgtcat tttcagcatg tgtttcggat ctttttgata tagggaatca agcaaataag
     9421 ctttccttgc atacataaat gctagtttat tcatatacat attactatat gataaactac
     9481 gcaattcatt tacaacccgc aaaggaatcg ttttcctgtt ctccgcttcg tccagtaatt
     9541 gcagagcacg cctaggttcg ggaatataaa tattcctgat atatttctcc gtatacagct
     9601 gtctcttata cacatctccg agcccacgag accgaggctg atct
//
